Jochen K Lennerz

Jochen K Lennerz

UNVERIFIED PROFILE

Are you Jochen K Lennerz?   Register this Author

Register author
Jochen K Lennerz

Jochen K Lennerz

Publications by authors named "Jochen K Lennerz"

Are you Jochen K Lennerz?   Register this Author

100Publications

2498Reads

36Profile Views

Tumour budding, poorly differentiated clusters, and T-cell response in colorectal cancer.

EBioMedicine 2020 Jul 8;57:102860. Epub 2020 Jul 8.

Program in MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA; Cancer Immunology and Cancer Epidemiology Programs, Dana-Farber Harvard Cancer Center, Boston, Massachusetts, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ebiom.2020.102860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347996PMC
July 2020

Personalized Diagnostic Workflows: The Next Wave of Precision Medicine in NSCLC.

J Thorac Oncol 2020 Jun;15(6):888-890

Center for Integrated Diagnostics, Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtho.2020.03.019DOI Listing
June 2020

Heparin-Coated Albumin Nanoparticles for Drug Combination in Targeting Inflamed Intestine.

Adv Healthc Mater 2020 Jun 29:e2000536. Epub 2020 Jun 29.

Division of Gastroenterology, Hepatology and Endoscopy, Department of Medicine, Brigham and Women's Hospital, Boston, MA, 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/adhm.202000536DOI Listing
June 2020

Clinicopathologic Characteristics of BRG1-Deficient NSCLC.

J Thorac Oncol 2020 May 24;15(5):766-776. Epub 2020 Jan 24.

Center for Integrated Diagnostics, Massachusetts General Hospital, Boston, Massachusetts. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtho.2020.01.002DOI Listing
May 2020

Response to RET-Specific Therapy in Fusion-Positive Anaplastic Thyroid Carcinoma.

Thyroid 2020 May 19. Epub 2020 May 19.

Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/thy.2019.0477DOI Listing
May 2020

Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group.

NPJ Breast Cancer 2020 12;6:16. Epub 2020 May 12.

74Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41523-020-0154-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217824PMC
May 2020

Computed Tomography Imaging Features and Distribution of Metastases in ROS1-rearranged Non-Small-cell Lung Cancer.

Clin Lung Cancer 2020 03 16;21(2):153-159.e3. Epub 2019 Oct 16.

Massachusetts General Hospital Cancer Center and Department of Medicine, Massachusetts General Hospital, Boston, MA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cllc.2019.10.006DOI Listing
March 2020

Clinicopathologic and Imaging Features of Non-Small-Cell Lung Cancer with Exon 14 Skipping Mutations.

Cancers (Basel) 2019 Dec 17;11(12). Epub 2019 Dec 17.

Massachusetts General Hospital Cancer Center and Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/cancers11122033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966679PMC
December 2019

Treatment with Next-Generation ALK Inhibitors Fuels Plasma Mutation Diversity.

Clin Cancer Res 2019 11 29;25(22):6662-6670. Epub 2019 Jul 29.

Massachusetts General Hospital Cancer Center and Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-19-1436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858956PMC
November 2019

Response to the Combination of Osimertinib and Trametinib in a Patient With EGFR-Mutant NSCLC Harboring an Acquired BRAF Fusion.

J Thorac Oncol 2019 10;14(10):e226-e228

Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtho.2019.05.046DOI Listing
October 2019

PAX8-positive Biphasic Synovial Sarcoma Expressing Hormonal Receptors.

Appl Immunohistochem Mol Morphol 2019 08;27(7):e71-e74

Department of Pathology, Massachusetts General Hospital, Boston.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PAI.0000000000000497DOI Listing
August 2019

Clinical Validation of a Cell-Free DNA Gene Panel.

J Mol Diagn 2019 07 23;21(4):632-645. Epub 2019 Apr 23.

Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmoldx.2019.02.008DOI Listing
July 2019

Ultra-rapid drug delivery in the oral cavity using ultrasound.

J Control Release 2019 06 27;304:1-6. Epub 2019 Apr 27.

Suono Bio, Inc., 501 Massachusetts Avenue, Cambridge, MA 02139, United States of America. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jconrel.2019.04.037DOI Listing
June 2019

Expediting Comprehensive Molecular Analysis to Optimize Initial Treatment of Lung Cancer Patients With Minimal Smoking History.

J Thorac Oncol 2019 05 18;14(5):835-843. Epub 2019 Jan 18.

Massachusetts General Hospital, Center for Integrated Diagnostics, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtho.2018.12.032DOI Listing
May 2019

Molecular Analysis of Plasma From Patients With ROS1-Positive NSCLC.

J Thorac Oncol 2019 05 18;14(5):816-824. Epub 2019 Jan 18.

Massachusetts General Hospital Cancer Center and Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtho.2019.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486857PMC
May 2019

Highly Multiplexed Fluorescence in Situ Hybridization for in Situ Genomics.

J Mol Diagn 2019 05 9;21(3):390-407. Epub 2019 Mar 9.

Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts; Cancer Center, Massachusetts General Hospital, Boston, Massachusetts. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmoldx.2019.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504678PMC
May 2019

Clinicopathological and molecular features of SF3B1-mutated myeloproliferative neoplasms.

Hum Pathol 2019 04 27;86:1-11. Epub 2018 Dec 27.

Department of Pathology, Massachusetts General Hospital, 02114 Boston, MA, USA; Harvard Medical School, 02114 Boston, MA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.humpath.2018.11.022DOI Listing
April 2019

Novel gene fusions in secretory carcinoma of the salivary glands: enlarging the ETV6 family.

Hum Pathol 2019 01 18;83:50-58. Epub 2018 Aug 18.

Department of Pathology, Massachusetts General Hospital, Boston, MA 02114-2696, USA; Department of Pathology, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.humpath.2018.08.011DOI Listing
January 2019

Impact of BRAF Mutation Class on Disease Characteristics and Clinical Outcomes in BRAF-mutant Lung Cancer.

Clin Cancer Res 2019 01 17;25(1):158-165. Epub 2018 Sep 17.

Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute Hospital, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-18-2062DOI Listing
January 2019

MET Amplification in Esophageal Squamous Carcinoma.

Int J Surg Pathol 2018 12 19;26(8):731-732. Epub 2018 Mar 19.

1 Massachusetts General Hospital, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1066896918764301DOI Listing
December 2018

The Amount of Bifidobacterium Genus in Colorectal Carcinoma Tissue in Relation to Tumor Characteristics and Clinical Outcome.

Am J Pathol 2018 12 20;188(12):2839-2852. Epub 2018 Sep 20.

Department of Oncologic Pathology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts; Broad Institute of MIT and Harvard, Cambridge, Massachusetts; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts; Program in MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajpath.2018.08.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284552PMC
December 2018

Recent advances in the histological and molecular classification of endometrial stromal neoplasms.

Virchows Arch 2018 Dec 15;473(6):665-678. Epub 2018 Oct 15.

Department of Pathology, Massachusetts General Hospital, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00428-018-2470-6DOI Listing
December 2018

Performance comparison of two androgen receptor splice variant 7 (AR-V7) detection methods.

BJU Int 2018 08 14;122(2):219-226. Epub 2018 Feb 14.

Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bju.14146DOI Listing
August 2018

Implementing Keytruda/Pembrolizumab Testing in Clinical Practice.

Oncologist 2018 06 9;23(6):647-649. Epub 2018 Mar 9.

Center for Integrated Diagnostics, Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA; Harvard Medical School, Boston, Massachusetts, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1634/theoncologist.2017-0591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067935PMC
June 2018

Food Addiction, High-Glycemic-Index Carbohydrates, and Obesity.

Clin Chem 2018 01 20;64(1):64-71. Epub 2017 Nov 20.

Massachusetts General Hospital, Department of Pathology, Center for Integrated Diagnostics & Harvard Medical School, Boston, MA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1373/clinchem.2017.273532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912158PMC
January 2018

Cost-effectiveness of IDH testing in diffuse gliomas according to the 2016 WHO classification of tumors of the central nervous system recommendations.

Neuro Oncol 2017 Nov;19(12):1640-1650

Department of Pathology; Department of Neurology, Division of Neuro-Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/neuonc/nox120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716163PMC
November 2017

Silencer of Cytokine Signaling 1 gene is not hypermethylated in diffuse large B-cell lymphoma.

Br J Haematol 2017 10 15;179(1):158-160. Epub 2016 Jun 15.

Institute of Pathology, University Ulm, Ulm, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bjh.14188DOI Listing
October 2017

Expression of Kallikrein-Related Peptidase 6 in Primary Mucosal Malignant Melanoma of the Head and Neck.

Head Neck Pathol 2017 Sep 14;11(3):314-320. Epub 2016 Nov 14.

Section Experimental and Translational Head and Neck Oncology, Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Heidelberg, Heidelberg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12105-016-0769-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550389PMC
September 2017

Origins of lymphatic and distant metastases in human colorectal cancer.

Science 2017 Jul;357(6346):55-60

Edwin L. Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.aai8515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536201PMC
July 2017

ROS1 Fusions Rarely Overlap with Other Oncogenic Drivers in Non-Small Cell Lung Cancer.

J Thorac Oncol 2017 05 11;12(5):872-877. Epub 2017 Jan 11.

Massachusetts General Hospital Cancer Center, Boston, Massachusetts; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtho.2017.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403618PMC
May 2017

Case 10-2017 - A 6-Month-Old Boy with Gastrointestinal Bleeding and Abdominal Pain.

N Engl J Med 2017 03;376(13):1269-1277

From the Departments of Emergency Medicine (L.M.A.), Radiology (R.L.), Surgery (A.M.G.), and Pathology (J.K.L.), Massachusetts General Hospital, and the Departments of Emergency Medicine (L.M.A.), Radiology (R.L.), Surgery (A.M.G.), and Pathology (J.K.L.), Harvard Medical School - both in Boston.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMcpc1616020DOI Listing
March 2017

Case 35-2016. A 62-Year-Old Man with Dysphagia.

N Engl J Med 2016 11;375(20):1983-1991

From the Departments of Medicine (E.L.K., D.G.F.), Radiation Oncology (T.S.H.), Radiology (A.K.), and Pathology (J.K.L.), Massachusetts General Hospital, and the Departments of Medicine (E.L.K., D.G.F.), Radiation Oncology (T.S.H.), Radiology (A.K.), and Pathology (J.K.L.), Harvard Medical School - both in Boston.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMcpc1610714DOI Listing
November 2016

ROS1 Rearrangement in Thyroid Cancer.

Thyroid 2016 06;26(6):794-7

1 Department of Pathology, Massachusetts General Hospital/Harvard Medical School , Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/thy.2016.0101DOI Listing
June 2016

Validation of a Manual Protocol for BRAF V600E Mutation-specific Immunohistochemistry.

Appl Immunohistochem Mol Morphol 2015 May-Jun;23(5):382-8

*Division of Molecular Diagnostics, Institute of Pathology, University Ulm, Ulm †Department of Neuropathology and Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Institute of Pathology, Ruprecht-Karls-Universität Heidelberg, Heidelberg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PAI.0000000000000092DOI Listing
February 2016

Identification and clinical relevance of PD-L1 expression in primary mucosal malignant melanoma of the head and neck.

Melanoma Res 2015 Dec;25(6):503-9

aDepartment of Otorhinolaryngology, Head and Neck Surgery bInstitute of Pathology, University Medical Center Ulm, Ulm cDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Essen, Essen dInstitute of Pathology eSection Experimental and Translational Head and Neck Oncology, Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Heidelberg fResearch Group Molecular Mechanisms of Head and Neck Tumors, German Cancer Research Center (DKFZ), Heidelberg gDepartment of Dermatology and Venerology, University Medical Center of Cologne, Cologne, Germany hDepartment of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CMR.0000000000000197DOI Listing
December 2015

ClinGen and Genetic Testing.

N Engl J Med 2015 10;373(14):1377-8

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMc1508700DOI Listing
October 2015

Classical pathology and mutational load of breast cancer - integration of two worlds.

J Pathol Clin Res 2015 Oct 20;1(4):225-38. Epub 2015 Jul 20.

Institute of Pathology, University Hospital HeidelbergHeidelbergGermany; Fellow of the NCT Heidelberg School of Oncology (NCT-HSO)HeidelbergGermany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cjp2.25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939893PMC
October 2015

Basket Trials: Just the End of the First Quarter.

J Clin Oncol 2015 Sep 13;33(25):2823-4. Epub 2015 Jul 13.

Charité University Hospital; Einstein Foundation, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2015.62.1516DOI Listing
September 2015

Allelic ratio of KRAS mutations in pancreatic cancer.

Oncologist 2015 Apr 16;20(4):e8-9. Epub 2015 Mar 16.

Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1634/theoncologist.2014-0408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391769PMC
April 2015

ATA clinical guidelines for telepathology.

Telemed J E Health 2014 Nov;20(11):1049-56

1 Department of Pathology, University of Pittsburgh Medical Center , Pittsburgh, Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/tmj.2014.9976DOI Listing
November 2014

Double-punching PMBL.

Authors:
Jochen K Lennerz

Oncotarget 2014 Nov;5(22):10965-6

Department of Pathology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://www.oncotarget.com/fulltext/2827
Publisher Site
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294352PMC
http://dx.doi.org/10.18632/oncotarget.2827DOI Listing
November 2014

Absence of BRAF and KRAS hotspot mutations in primary mediastinal B-cell lymphoma.

Leuk Lymphoma 2014 Oct 4;55(10):2389-90. Epub 2014 Feb 4.

Institute of Pathology, University Ulm , Ulm , Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/10428194.2013.878461DOI Listing
October 2014

Comparison of MelanA/MART-1 and HMB45 labeling in desmoplastic melanoma.

Mod Pathol 2014 Oct;27(10):1421-3

Institute of Pathology, University Ulm, Ulm, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/modpathol.2014.59DOI Listing
October 2014

Invasion pattern and histologic features of tumor aggressiveness correlate with MMR protein expression, but are independent of activating KRAS and BRAF mutations in CRC.

Virchows Arch 2014 Aug 12;465(2):155-63. Epub 2014 Jun 12.

Bundeswehr Institute of Radiobiology, Neuherbergstrasse 11, 80937, Munich, Germany,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00428-014-1604-8DOI Listing
August 2014

A diagnostic algorithm to distinguish desmoplastic from spindle cell melanoma.

Mod Pathol 2014 Apr 20;27(4):524-34. Epub 2013 Sep 20.

Institute of Pathology, University of Ulm, Ulm, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/modpathol.2013.162DOI Listing
April 2014

Transitory dasatinib-resistant states in KIT(mut) t(8;21) acute myeloid leukemia cells correlate with altered KIT expression.

Exp Hematol 2014 Feb 6;42(2):90-100. Epub 2013 Nov 6.

Department of Pediatrics and Adolescent Medicine, University Medical Center, Ulm, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exphem.2013.10.006DOI Listing
February 2014

Jaundice in resected pancreatic cancer patients.

HPB (Oxford) 2014 Feb;16(2):195

Institute of Pathology, University of Ulm, Ulm, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/hpb.12158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921017PMC
February 2014

Absence of FLICE-inhibitory protein is a novel independent prognostic marker for very short survival in pancreatic ductal adenocarcinoma.

Pancreas 2013 Oct;42(7):1114-9

From the *Department of Pathology, †Comprehensive Cancer Center Ulm, and Departments of ‡General, Visceral and Transplantation Surgery and §Internal Medicine, University Hospital Ulm, Germany; and ∥Institute for Experimental Cancer Research in Pediatrics, Goethe-University Frankfurt, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MPA.0b013e31829655edDOI Listing
October 2013