Jochen Herms

Jochen Herms

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Jochen Herms

Publications by authors named "Jochen Herms"

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Loss of fragile X mental retardation protein precedes Lewy pathology in Parkinson's disease.

Acta Neuropathol 2020 Feb 25;139(2):319-345. Epub 2019 Nov 25.

Department of Translational Neurodegeneration, German Centre for Neurodegenerative Diseases (DZNE), Munich, Germany.

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http://dx.doi.org/10.1007/s00401-019-02099-5DOI Listing
February 2020

Early defects in translation elongation factor 1α levels at excitatory synapses in α-synucleinopathy.

Acta Neuropathol 2019 Dec 26;138(6):971-986. Epub 2019 Aug 26.

Center for Neuropathology and Prion Research, Ludwig-Maximilians University, Munich, Germany.

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http://dx.doi.org/10.1007/s00401-019-02063-3DOI Listing
December 2019

Non-invasive prediction of IDH-wildtype genotype in gliomas using dynamic F-FET PET.

Eur J Nucl Med Mol Imaging 2019 Nov 13;46(12):2581-2589. Epub 2019 Aug 13.

Department of Nuclear Medicine, University Hospital, Ludwig Maximilians-University Munich, Munich, Germany.

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http://dx.doi.org/10.1007/s00259-019-04477-3DOI Listing
November 2019

Bevacizumab reduces toxicity of reirradiation in recurrent high-grade glioma.

Radiother Oncol 2019 09 25;138:99-105. Epub 2019 Jun 25.

Department of Radiation Oncology, University Hospital, LMU Munich, Germany; German Cancer Consortium (DKTK), Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.radonc.2019.06.009DOI Listing
September 2019

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.

Authors:
Cyril Pottier Yingxue Ren Ralph B Perkerson Matt Baker Gregory D Jenkins Marka van Blitterswijk Mariely DeJesus-Hernandez Jeroen G J van Rooij Melissa E Murray Elizabeth Christopher Shannon K McDonnell Zachary Fogarty Anthony Batzler Shulan Tian Cristina T Vicente Billie Matchett Anna M Karydas Ging-Yuek Robin Hsiung Harro Seelaar Merel O Mol Elizabeth C Finger Caroline Graff Linn Öijerstedt Manuela Neumann Peter Heutink Matthis Synofzik Carlo Wilke Johannes Prudlo Patrizia Rizzu Javier Simon-Sanchez Dieter Edbauer Sigrun Roeber Janine Diehl-Schmid Bret M Evers Andrew King M Marsel Mesulam Sandra Weintraub Changiz Geula Kevin F Bieniek Leonard Petrucelli Geoffrey L Ahern Eric M Reiman Bryan K Woodruff Richard J Caselli Edward D Huey Martin R Farlow Jordan Grafman Simon Mead Lea T Grinberg Salvatore Spina Murray Grossman David J Irwin Edward B Lee EunRan Suh Julie Snowden David Mann Nilufer Ertekin-Taner Ryan J Uitti Zbigniew K Wszolek Keith A Josephs Joseph E Parisi David S Knopman Ronald C Petersen John R Hodges Olivier Piguet Ethan G Geier Jennifer S Yokoyama Robert A Rissman Ekaterina Rogaeva Julia Keith Lorne Zinman Maria Carmela Tartaglia Nigel J Cairns Carlos Cruchaga Bernardino Ghetti Julia Kofler Oscar L Lopez Thomas G Beach Thomas Arzberger Jochen Herms Lawrence S Honig Jean Paul Vonsattel Glenda M Halliday John B Kwok Charles L White Marla Gearing Jonathan Glass Sara Rollinson Stuart Pickering-Brown Jonathan D Rohrer John Q Trojanowski Vivianna Van Deerlin Eileen H Bigio Claire Troakes Safa Al-Sarraj Yan Asmann Bruce L Miller Neill R Graff-Radford Bradley F Boeve William W Seeley Ian R A Mackenzie John C van Swieten Dennis W Dickson Joanna M Biernacka Rosa Rademakers

Acta Neuropathol 2019 06 9;137(6):879-899. Epub 2019 Feb 9.

Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.

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http://link.springer.com/10.1007/s00401-019-01962-9
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http://dx.doi.org/10.1007/s00401-019-01962-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533145PMC
June 2019

In vivo Ca imaging of astrocytic microdomains reveals a critical role of the amyloid precursor protein for mitochondria.

Glia 2019 05 22;67(5):985-998. Epub 2019 Jan 22.

Division of Translational Brain Research, German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.

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http://dx.doi.org/10.1002/glia.23584DOI Listing
May 2019

Tcf4 regulates dendritic spine density and morphology in the adult brain.

PLoS One 2018 22;13(6):e0199359. Epub 2018 Jun 22.

Center for Neuropathology, Ludwig-Maximilian-University, Munich, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0199359PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014661PMC
April 2019

Translational control in brain pathologies: biological significance and therapeutic opportunities.

Acta Neuropathol 2019 04 9;137(4):535-555. Epub 2019 Feb 9.

Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, BC, V5Z 1L3, Canada.

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http://dx.doi.org/10.1007/s00401-019-01971-8DOI Listing
April 2019

In vivo imaging reveals reduced activity of neuronal circuits in a mouse tauopathy model.

Brain 2019 04;142(4):1051-1062

Department for Translational Brain Research, German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.

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http://dx.doi.org/10.1093/brain/awz035DOI Listing
April 2019

Unbalanced calcium channel activity underlies selective vulnerability of nigrostriatal dopaminergic terminals in Parkinsonian mice.

Sci Rep 2019 Mar 19;9(1):4857. Epub 2019 Mar 19.

Transgenic Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1038/s41598-019-41091-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425036PMC
March 2019

Consequences of Pharmacological BACE Inhibition on Synaptic Structure and Function.

Biol Psychiatry 2018 10 23;84(7):478-487. Epub 2018 Jun 23.

Department for Translational Brain Research, German Center for Neurodegenerative Diseases, Munich, Germany; Munich Cluster for Systems Neurology, Ludwig-Maximilians-University Munich, Munich, Germany; Center for Neuropathology and Prion Research, Ludwig-Maximilians-University Munich, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2018.04.022DOI Listing
October 2018

Label-free 3D-CLEM Using Endogenous Tissue Landmarks.

iScience 2018 Aug 20;6:92-101. Epub 2018 Jul 20.

Department of Biology I, Biocenter Ludwig-Maximilians-University Munich, Planegg-Martinsried 82152, Germany; German Center for Neurodegenerative Diseases (DZNE), Translational Brain Research, Munich 81377, Germany; Center for Neuropathology, Ludwig-Maximilians-University Munich, Munich 81377, Germany; Munich Cluster of Systems Neurology (SyNergy), Munich 81377, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S25890042183010
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http://dx.doi.org/10.1016/j.isci.2018.07.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137285PMC
August 2018

BACE1 Inhibitor MK-8931 Alters Formation but Not Stability of Dendritic Spines.

Front Aging Neurosci 2018 26;10:229. Epub 2018 Jul 26.

Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Helmholtz-Gemeinschaft Deutscher Forschungszentren (HZ)-German Center for Neurodegenerative Diseases, Munich, Germany.

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http://dx.doi.org/10.3389/fnagi.2018.00229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070607PMC
July 2018

BACE1 inhibition more effectively suppresses initiation than progression of β-amyloid pathology.

Acta Neuropathol 2018 05 11;135(5):695-710. Epub 2018 Jan 11.

German Center for Neurodegenerative Diseases (DZNE), Feodor-Lynen Str. 17, 81377, Munich, Germany.

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http://dx.doi.org/10.1007/s00401-017-1804-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904228PMC
May 2018

Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibition Impairs Synaptic Plasticity via Seizure Protein 6.

Biol Psychiatry 2018 03 26;83(5):428-437. Epub 2016 Dec 26.

German Center for Neurodegenerative Diseases, Munich, Germany; Center for Neuropathology and Prion Research, Munich, Germany; Munich Cluster for Systems Neurology, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2016.12.023DOI Listing
March 2018

In Vivo Imaging of Tau Aggregates in the Mouse Retina.

Methods Mol Biol 2017 ;1523:361-368

Department of Translational Brain Research, DZNE - German Centre for Neurodegenerative Diseases, Munich, Germany.

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http://dx.doi.org/10.1007/978-1-4939-6598-4_24DOI Listing
January 2018

Ambient Glutamate Promotes Paroxysmal Hyperactivity in Cortical Pyramidal Neurons at Amyloid Plaques via Presynaptic mGluR1 Receptors.

Cereb Cortex 2017 10;27(10):4733-4749

German Center for Neurodegenerative Diseases (DZNE), Feodor-Lynen-Straße 17, 81377 Munich, Germany.

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http://dx.doi.org/10.1093/cercor/bhw267DOI Listing
October 2017

Neurogenesis from Sox2 expressing cells in the adult cerebellar cortex.

Sci Rep 2017 07 21;7(1):6137. Epub 2017 Jul 21.

Center for Neuropathology, Ludwig-Maximilians-University, Munich, Germany.

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http://dx.doi.org/10.1038/s41598-017-06150-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522437PMC
July 2017

In vivo imaging of retinal neurodegeneration at the single cell level in humans.

Brain 2017 06;140(6):1542-1543

Center for Integrated Protein Science Munich CiPSM and Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität München, Munich, Germany.

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http://dx.doi.org/10.1093/brain/awx100DOI Listing
June 2017

The Role of APP in Structural Spine Plasticity.

Front Mol Neurosci 2017 10;10:136. Epub 2017 May 10.

Department for Translational Brain Research, German Center for Neurodegenerative Diseases (DZNE), Ludwig-Maximilian-University MunichMunich, Germany.

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http://dx.doi.org/10.3389/fnmol.2017.00136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423954PMC
May 2017

High plasticity of axonal pathology in Alzheimer's disease mouse models.

Acta Neuropathol Commun 2017 Feb 7;5(1):14. Epub 2017 Feb 7.

German Center for Neurodegenerative Diseases-Munich site (DZNE-M) and Center for Neuropathology and Prion Research (ZNP), Ludwig-Maximilians University, Munich, Feodor-Lynen-St 23, 81377, Munich, Germany.

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http://dx.doi.org/10.1186/s40478-017-0415-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296955PMC
February 2017

Glial Activation and Glucose Metabolism in a Transgenic Amyloid Mouse Model: A Triple-Tracer PET Study.

J Nucl Med 2016 06 18;57(6):954-60. Epub 2016 Feb 18.

Department of Nuclear Medicine, Ludwig-Maximilians-University of Munich, Munich, Germany SyNergy, Ludwig-Maximilians-University of Munich, Munich, Germany; and

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http://dx.doi.org/10.2967/jnumed.115.167858DOI Listing
June 2016

Dendritic Spine Pathology in Neurodegenerative Diseases.

Annu Rev Pathol 2016 05 22;11:221-50. Epub 2016 Feb 22.

Center for Neuropathology and Prion Research, Ludwig Maximilian University, 81377 Munich, Germany; email:

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http://dx.doi.org/10.1146/annurev-pathol-012615-044216DOI Listing
May 2016

Small-Animal PET Imaging of Tau Pathology with 18F-THK5117 in 2 Transgenic Mouse Models.

J Nucl Med 2016 05 11;57(5):792-8. Epub 2016 Feb 11.

Department of Nuclear Medicine, Ludwig-Maximilians-University of Munich, Munich, Germany Munich Cluster for Systems Neurology (SyNergy), Munich, Germany

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http://dx.doi.org/10.2967/jnumed.115.163493DOI Listing
May 2016

Fibrillar amyloid plaque formation precedes microglial activation.

PLoS One 2015 23;10(3):e0119768. Epub 2015 Mar 23.

Department for Translational Brain Research, German Center for Neurodegenerative Diseases-site Munich (DZNE-M) and Center for Neuropathology and Prion Research (ZNP), Ludwig-Maximilians-University Munich, Munich, Germany; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0119768PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370641PMC
March 2016

Loss of HCN1 enhances disease progression in mouse models of CNG channel-linked retinitis pigmentosa and achromatopsia.

Hum Mol Genet 2016 Mar 5;25(6):1165-75. Epub 2016 Jan 5.

Center for Integrated Protein Science Munich CiPSM at the Department of Pharmacy - Center for Drug Research,

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http://dx.doi.org/10.1093/hmg/ddv639DOI Listing
March 2016

Neuroinflammation impairs adaptive structural plasticity of dendritic spines in a preclinical model of Alzheimer's disease.

Acta Neuropathol 2016 Feb 2;131(2):235-246. Epub 2016 Jan 2.

Department for Translational Brain Research, German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.

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http://dx.doi.org/10.1007/s00401-015-1527-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713725PMC
February 2016

Analyzing dendritic spine pathology in Alzheimer's disease: problems and opportunities.

Acta Neuropathol 2015 Jul 11;130(1):1-19. Epub 2015 Jun 11.

Ludwig-Maximilians University Munich, Center for Neuropathology and Prion Research, Feodor-Lynen-Str. 23, 81377, Munich, Germany.

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http://dx.doi.org/10.1007/s00401-015-1449-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469300PMC
July 2015

Intraneuronal APP and extracellular Aβ independently cause dendritic spine pathology in transgenic mouse models of Alzheimer's disease.

Acta Neuropathol 2015 Jun 11;129(6):909-20. Epub 2015 Apr 11.

Department for Translational Brain Research, German Center for Neurodegeneratione Diseases (DZNE), Ludwig-Maximilians-University Munich, Munich, Germany.

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http://dx.doi.org/10.1007/s00401-015-1421-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436699PMC
June 2015

Pharmacological inhibition of BACE1 impairs synaptic plasticity and cognitive functions.

Biol Psychiatry 2015 Apr 29;77(8):729-39. Epub 2014 Oct 29.

German Center for Neurodegenerative Diseases, Ludwig Maximilian University Munich, Munich, Germany; Center for Neuropathology, Ludwig Maximilian University Munich, Munich, Germany; Munich Cluster of Systems Neurology (SyNergy), Ludwig Maximilian University Munich, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2014.10.013DOI Listing
April 2015

Immunotherapy alleviates amyloid-associated synaptic pathology in an Alzheimer's disease mouse model.

Brain 2014 Dec 3;137(Pt 12):3319-26. Epub 2014 Oct 3.

1 Centre for Neuropathology and Prion Research, Ludwig Maximilian University, Feodor-Lynen-Str. 23, 81377 Munich, Germany 2 Department of Translational Brain Research, German Centre for Neurodegenerative Diseases (DZNE), Feodor-Lynen-Str. 23, 81377 Munich, Germany 5 Munich Cluster of Systems Neurology (SyNergy), Ludwig Maximilian University, Schillerstraße 44, 80336 Munich, Germany

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http://dx.doi.org/10.1093/brain/awu280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240293PMC
December 2014

Neurotrophin receptor p75 mediates the uptake of the amyloid beta (Aβ) peptide, guiding it to lysosomes for degradation in basal forebrain cholinergic neurons.

Brain Struct Funct 2014 Sep 29;219(5):1527-41. Epub 2013 May 29.

International Centre for Neurotherapeutics, Dublin City University, Glasnevin, Dublin 9, Republic of Ireland,

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http://dx.doi.org/10.1007/s00429-013-0583-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675333PMC
September 2014

An assay to image neuronal microtubule dynamics in mice.

Nat Commun 2014 Sep 12;5:4827. Epub 2014 Sep 12.

1] Institute of Neuronal Cell Biology, Technische Universität München, 80802 Munich, Germany [2] German Center for Neurodegenerative Diseases (DZNE), 80336 Munich, Germany [3] Munich Cluster for Systems Neurology (SyNergy), 80336 Munich, Germany [4] Center of Integrated Protein Science (CIPSM), 81377 Munich, Germany.

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http://dx.doi.org/10.1038/ncomms5827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175586PMC
September 2014

Development and implementation of a high-throughput compound screening assay for targeting disrupted ER calcium homeostasis in Alzheimer's disease.

PLoS One 2013 15;8(11):e80645. Epub 2013 Nov 15.

Department of Translational Brain Research, DZNE - German Center for Neurodegenerative Diseases, Munich, Germany ; Center for Neuropathology and Prion Research; Ludwig Maximilian University, Munich, Germany ; Graduate School of Systemic Neurosciences, Ludwig Maximilian University, Munich, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0080645PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829862PMC
August 2014

Molecular stereotactic biopsy technique improves diagnostic accuracy and enables personalized treatment strategies in glioma patients.

Acta Neurochir (Wien) 2014 Aug 3;156(8):1427-40. Epub 2014 May 3.

Center for Neuropathology and Prion Research, University of Munich Medical Center - Grosshadern, Ludwig-Maximilians-University, Marchioninistr. 15, 81377, Munich, Germany.

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http://link.springer.com/10.1007/s00701-014-2073-1
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http://dx.doi.org/10.1007/s00701-014-2073-1DOI Listing
August 2014

Pathological α-synuclein impairs adult-born granule cell development and functional integration in the olfactory bulb.

Nat Commun 2014 May 28;5:3915. Epub 2014 May 28.

1] German Center for Neurodegeneratione Diseases (DZNE), Department for Translational Brain Research, Feodor-Lynen-Strasse 23, Munich 81377, Germany [2] Munich Cluster of Systems Neurology (SyNergy), Ludwig Maximilian University, Feodor-Lynen-Strasse 23, Munich 81377, Germany.

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http://dx.doi.org/10.1038/ncomms4915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050256PMC
May 2014

In memoriam: Hans A. Kretzschmar (1953-2014).

Authors:
Jochen Herms

Brain Pathol 2014 Apr;24(3):311-2

Department of Translational Brain Research, German Center for Neurodegenerative Diseases (DZNE), Ludwig-Maximilians-University Munich, Feodor-Lynen-Str. 23, 81377, München, Germany.

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http://dx.doi.org/10.1111/bpa.12145DOI Listing
April 2014

In vivo imaging reveals sigmoidal growth kinetic of β-amyloid plaques.

Acta Neuropathol Commun 2014 Mar 28;2:30. Epub 2014 Mar 28.

German Center for Neurodegenerative Diseases (DZNE), Ludwig-Maximilians-University Munich, Feodor-Lynen-Str, 23, 81377 Munich, Germany.

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http://dx.doi.org/10.1186/2051-5960-2-30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050984PMC
March 2014

Structural dynamics of dendritic spines are influenced by an environmental enrichment: an in vivo imaging study.

Cereb Cortex 2014 Feb 18;24(2):377-84. Epub 2012 Oct 18.

Department of Translational Brain Research, DZNE-German Center for Neurodegenerative Diseases, Munich, Germany.

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http://dx.doi.org/10.1093/cercor/bhs317DOI Listing
February 2014

A30P α-Synuclein interferes with the stable integration of adult-born neurons into the olfactory network.

Sci Rep 2014 Feb 3;4:3931. Epub 2014 Feb 3.

1] German Center for Neurodegenerative Diseases (DZNE), Munich, Schillerstraße 44, 80336 Munich, Germany [2] Munich Cluster of Systems Neurology (SyNergy), Ludwig Maximilian University Munich, Schillerstraße 44, 80336 Munich, Germany.

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http://dx.doi.org/10.1038/srep03931DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909899PMC
February 2014

FRET-based calcium imaging: a tool for high-throughput/content phenotypic drug screening in Alzheimer disease.

J Biomol Screen 2013 Dec;18(10):1309-20

1Department of Translational Brain Research, DZNE-German Center for Neurodegenerative Diseases, Munich, Germany.

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http://journals.sagepub.com/doi/10.1177/1087057113502672
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http://dx.doi.org/10.1177/1087057113502672DOI Listing
December 2013

Impaired plasticity of cortical dendritic spines in P301S tau transgenic mice.

Acta Neuropathol Commun 2013 Dec 17;1:82. Epub 2013 Dec 17.

Department of Translational Brain Research, German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.

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http://dx.doi.org/10.1186/2051-5960-1-82DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880070PMC
December 2013

Cholinergic neurons-keeping check on amyloid β in the cerebral cortex.

Front Cell Neurosci 2013 11;7:252. Epub 2013 Dec 11.

Department of Translational Brain Research, German Center for Neurodegenerative Diseases (DZNE) Munich, Germany ; Center for Neuropathology and Prion Research, Ludwig Maximilian University Munich, Germany ; Munich Cluster for Systems Neurology (SyNerg) Munich, Germany.

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http://dx.doi.org/10.3389/fncel.2013.00252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858826PMC
December 2013

Drain of the brain: low-affinity p75 neurotrophin receptor affords a molecular sink for clearance of cortical amyloid β by the cholinergic modulator system.

Neurobiol Aging 2013 Nov 5;34(11):2517-24. Epub 2013 Jun 5.

Department of Translational Brain Research, German Center for Neurodegenerative Diseases, DZNE, Munich, Germany.

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http://dx.doi.org/10.1016/j.neurobiolaging.2013.05.005DOI Listing
November 2013

Fluorescent rhodanine-3-acetic acids visualize neurofibrillary tangles in Alzheimer's disease brains.

Bioorg Med Chem 2013 Sep 27;21(17):5139-44. Epub 2013 Jun 27.

Clemens Schöpf-Institute of Chemistry and Biochemistry, Technische Universität Darmstadt, Petersenstrasse 22, Darmstadt 64287, Germany.

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http://dx.doi.org/10.1016/j.bmc.2013.06.039DOI Listing
September 2013

Involvement of presenilin holoprotein upregulation in calcium dyshomeostasis of Alzheimer's disease.

J Cell Mol Med 2013 Feb 5;17(2):293-302. Epub 2013 Feb 5.

Department of Translational Brain Research, DZNE - German Center for Neurodegenerative Diseases, Munich, Germany.

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http://dx.doi.org/10.1111/jcmm.12008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822592PMC
February 2013

Amyloid plaque formation precedes dendritic spine loss.

Acta Neuropathol 2012 Dec 21;124(6):797-807. Epub 2012 Sep 21.

Center for Neuropathology, Ludwig-Maximilians University, Munich, Germany.

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http://dx.doi.org/10.1007/s00401-012-1047-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508278PMC
December 2012

Presenilins: role in calcium homeostasis.

Int J Biochem Cell Biol 2012 Nov 27;44(11):1983-6. Epub 2012 Jul 27.

Department of Translational Brain Research, DZNE - German Center for Neurodegenerative Diseases, Munich, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S135727251200264
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http://dx.doi.org/10.1016/j.biocel.2012.07.019DOI Listing
November 2012

Arc illuminates Alzheimer's pathophysiology.

Nat Neurosci 2012 Oct;15(10):1323-5

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http://dx.doi.org/10.1038/nn.3226DOI Listing
October 2012

A window into metastasis.

Sci Transl Med 2012 Oct;4(158):158fs39

Center for Neuropathology and Prion Research, Ludwig Maximilian University, Munich 81377, Germany.

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http://dx.doi.org/10.1126/scitranslmed.3005053DOI Listing
October 2012

Role of APP for dendritic spine formation and stability.

Exp Brain Res 2012 Apr 18;217(3-4):463-70. Epub 2011 Nov 18.

Center of Neuropathology and Prion Research, Ludwig Maximilians Universität, Feodor-Lynen-Str. 23, 81377 Munich, Germany.

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http://dx.doi.org/10.1007/s00221-011-2939-xDOI Listing
April 2012

Lack of Pur-alpha alters postnatal brain development and causes megalencephaly.

Hum Mol Genet 2012 Feb 18;21(3):473-84. Epub 2011 Oct 18.

Center of Neuropathology and Prion Research, Ludwig-Maximilians-Universität and German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.

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http://dx.doi.org/10.1093/hmg/ddr476DOI Listing
February 2012

Role of presenilin 1 in structural plasticity of cortical dendritic spines in vivo.

J Neurochem 2011 Dec 24;119(5):1064-73. Epub 2011 Oct 24.

Center for Neuropathology and Prion Research, Laboratory of Experimental Neuropathology, Ludwig-Maximilian-University, Munich, Germany.

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http://dx.doi.org/10.1111/j.1471-4159.2011.07503.xDOI Listing
December 2011

Bevacizumab has differential and dose-dependent effects on glioma blood vessels and tumor cells.

Clin Cancer Res 2011 Oct 25;17(19):6192-205. Epub 2011 Jul 25.

Department of Neurology, University Hospital, Ludwig-Maximilians University, Munich, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-1868DOI Listing
October 2011

4D in in vivo 2-photon laser scanning fluorescence microscopy with sample motion in 6 degrees of freedom.

J Neurosci Methods 2011 Aug 23;200(1):47-53. Epub 2011 Jun 23.

Center of Neuropathology and Prion Research, Ludwig-Maximilians-Universität, Feodor-Lynen-Str. 23, D-81377 Munich, Germany.

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http://dx.doi.org/10.1016/j.jneumeth.2011.06.013DOI Listing
August 2011

AMPA-receptor-mediated excitatory synaptic transmission is enhanced by iron-induced α-synuclein oligomers.

J Neurochem 2011 Jun 26;117(5):868-78. Epub 2011 Apr 26.

Center of Neuropathology and Prion Research, Ludwig Maximilians University, Munich, Germany.

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http://dx.doi.org/10.1111/j.1471-4159.2011.07254.xDOI Listing
June 2011

5-Aminolevulinic acid-induced protoporphyrin IX levels in tissue of human malignant brain tumors.

Photochem Photobiol 2010 Nov-Dec;86(6):1373-8. Epub 2010 Sep 20.

Laser-Forschungslabor, University Clinic Großhadern, Munich, Germany.

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http://dx.doi.org/10.1111/j.1751-1097.2010.00799.xDOI Listing
March 2011

In vivo multiphoton imaging reveals gradual growth of newborn amyloid plaques over weeks.

Acta Neuropathol 2011 Mar 7;121(3):327-35. Epub 2010 Dec 7.

Center of Neuropathology and Prion Research, Ludwig Maximilians Universität, Feodor-Lynen-Strasse 23, Munich, Germany.

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http://dx.doi.org/10.1007/s00401-010-0787-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038220PMC
March 2011

Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease.

Nat Neurosci 2010 Apr 21;13(4):411-3. Epub 2010 Mar 21.

Center of Neuropathology and Prion Research, Ludwig-Maximilians-University, Munich, Germany.

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http://dx.doi.org/10.1038/nn.2511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072212PMC
April 2010

Real-time imaging reveals the single steps of brain metastasis formation.

Nat Med 2010 Jan 20;16(1):116-22. Epub 2009 Dec 20.

Department of Neurology, Ludwig-Maximilians University, Munich, Germany.

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http://dx.doi.org/10.1038/nm.2072DOI Listing
January 2010