Publications by authors named "Jochen H Lorch"

50Publications

Histopathologic Features and Clinical Outcome of Anaplastic Thyroid Carcinoma with a Minor Anaplastic Component.

Endocr Pathol 2020 Sep;31(3):283-290

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12022-020-09627-0DOI Listing
September 2020

Histologic Features of BRAF V600E-Mutant Anaplastic Thyroid Carcinoma.

Histopathology 2020 May 19. Epub 2020 May 19.

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/his.14144DOI Listing
May 2020

Long-term outcomes and clinicogenomic correlates in recurrent, metastatic adenoid cystic carcinoma.

Oral Oncol 2020 07 11;106:104690. Epub 2020 Apr 11.

Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA; BC Cancer, Vancouver Centre, 600 West 10th Avenue, Vancouver, BC V5Z 4E6, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.oraloncology.2020.104690DOI Listing
July 2020

Chemotherapy after immune checkpoint blockade in patients with recurrent, metastatic squamous cell carcinoma of the head and neck.

Oral Oncol 2020 06 3;105:104676. Epub 2020 Apr 3.

Dana-Farber Cancer Institute, 450 Brookline Ave, Boston, MA 02215, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.oraloncology.2020.104676DOI Listing
June 2020

The Safety and Efficacy of Checkpoint Inhibitors in Transplant Recipients: A Case Series and Systematic Review of Literature.

Oncologist 2020 Jun 11;25(6):505-514. Epub 2020 Feb 11.

Department of Medical Oncology, Dana Farber Cancer Institute and Brigham and Women's Hospital, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1634/theoncologist.2019-0659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288631PMC
June 2020

A potential diagnostic pitfall for hobnail variant of papillary thyroid carcinoma.

Histopathology 2020 Apr 13;76(5):707-713. Epub 2020 Apr 13.

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/his.14042DOI Listing
April 2020

Treatment of Aggressive Thyroid Cancer.

Surg Pathol Clin 2019 Dec;12(4):943-950

Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, D2136, Boston, MA 02115, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.path.2019.08.004DOI Listing
December 2019

Ketogenic diet combined with antioxidant N-acetylcysteine inhibits tumor growth in a mouse model of anaplastic thyroid cancer.

Surgery 2020 01 12;167(1):87-93. Epub 2019 Sep 12.

Department of Surgery, Brigham and Women's Hospital, Boston, MA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.surg.2019.06.042DOI Listing
January 2020

Prognostic Significance of Extent of Invasion in Poorly Differentiated Thyroid Carcinoma.

Thyroid 2019 09;29(9):1255-1261

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

View Article

Download full-text PDF

Source
https://www.liebertpub.com/doi/10.1089/thy.2019.0263
Publisher Site
http://dx.doi.org/10.1089/thy.2019.0263DOI Listing
September 2019

Clinicopathologic Features of Mismatch Repair-Deficient Anaplastic Thyroid Carcinomas.

Thyroid 2019 05 16;29(5):666-673. Epub 2019 Apr 16.

1 Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/thy.2018.0716DOI Listing
May 2019

Radiologic predictors of immune checkpoint inhibitor response in advanced head and neck squamous cell carcinoma.

Oral Oncol 2018 10 17;85:29-34. Epub 2018 Aug 17.

Department of Radiation Oncology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, Boston, MA 703-389-1895, United States. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S13688375183029
Publisher Site
http://dx.doi.org/10.1016/j.oraloncology.2018.08.005DOI Listing
October 2018

Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids.

Cancer Discov 2018 02 3;8(2):196-215. Epub 2017 Nov 3.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2159-8290.CD-17-0833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809290PMC
February 2018

A case of primary secretory carcinoma of the thyroid with high-grade features.

Histopathology 2017 10 13;71(4):665-669. Epub 2017 Jul 13.

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/his.13268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927591PMC
October 2017

Epstein-Barr virus-specific adoptive immunotherapy for recurrent, metastatic nasopharyngeal carcinoma.

Cancer 2017 Jul 21;123(14):2642-2650. Epub 2017 Feb 21.

Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.30541DOI Listing
July 2017

Exceptional Responders Inspire Change: Lessons for Drug Development From the Bedside to the Bench and Back.

Oncologist 2015 Jul 3;20(7):699-701. Epub 2015 Jun 3.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1634/theoncologist.2014-0476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492235PMC
July 2015

Genomic analysis of metastatic cutaneous squamous cell carcinoma.

Clin Cancer Res 2015 Mar 14;21(6):1447-56. Epub 2015 Jan 14.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts. Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts. Department of Medicine, Harvard Medical School, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-14-1773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359951PMC
March 2015

Response and acquired resistance to everolimus in anaplastic thyroid cancer.

N Engl J Med 2014 Oct;371(15):1426-33

From the Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School (N.W., E.M.V.A., N.G., R.I.H., D.J.K., P.A.J., L.A.G., J.H.L.), the Department of Medicine, Brigham and Women's Hospital and Harvard Medical School (N.W., E.M.V.A., Y.G., R.I.H., D.J.K., P.A.J., L.A.G., J.H.L.), the Departments of Pathology (J.A.B.) and Surgery (S.J.S., D.T.R.), Brigham and Women's Hospital, the Department of Medicine, Beth Israel Deaconess Medical Center (G.J.H.), and Belfer Institute for Applied Cancer Science, Dana-Farber Cancer Institute (P.A.J.) - all in Boston; and Broad Institute of the Massachusetts Institute of Technology (MIT) and Harvard (N.W., E.M.V.A., A.A.-M., A.T.-W., M.R., G.G., D.J.K., S.L.C., D.M.S., L.A.G.), Whitehead Institute for Biomedical Research and the MIT Department of Biology (B.C.G., D.M.S.), and Howard Hughes Medical Institute, MIT (B.C.G., D.M.S.) - all in Cambridge, MA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa1403352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564868PMC
October 2014

Induction chemotherapy for locoregionally advanced head and neck cancer: past, present, future?

Oncologist 2013 26;18(3):288-93. Epub 2013 Feb 26.

Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1634/theoncologist.2012-0286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607525PMC
September 2013

Trastuzumab for the treatment of salivary duct carcinoma.

Oncologist 2013 21;18(3):294-300. Epub 2013 Feb 21.

Department of Medical Oncology, Dana-Farber Cancer Institute/Harvard Medical School, Boston, Massachusetts 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1634/theoncologist.2012-0369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607526PMC
September 2013

Autophagic activation potentiates the antiproliferative effects of tyrosine kinase inhibitors in medullary thyroid cancer.

Surgery 2012 Dec;152(6):1142-9

Department of Surgery, Brigham and Women's Hospital, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.surg.2012.08.016DOI Listing
December 2012

Role of EGF inhibitors in the treatment of recurrent or metastatic squamous cell head and neck cancer.

Authors:
Jochen H Lorch

Cancer Manag Res 2009 Nov 3;1:151-4. Epub 2009 Nov 3.

Dana Farber Cancer Institute, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004660PMC
http://dx.doi.org/10.2147/cmr.s5134DOI Listing
November 2009

Seeking alternative biological therapies: the future of targeted molecular treatment.

Oral Oncol 2009 Apr-May;45(4-5):447-53. Epub 2008 Nov 21.

Dana Farber Cancer Institute, 44 Binney Street, SW430, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.oraloncology.2008.08.009DOI Listing
May 2010

Induction chemotherapy in locally advanced head and neck cancer: a new standard of care?

Hematol Oncol Clin North Am 2008 Dec;22(6):1155-63, viii

Dana Farber Cancer Institute, SW430, 44 Binney Street, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hoc.2008.08.004DOI Listing
December 2008

Bortezomib inhibits cell-cell adhesion and cell migration and enhances epidermal growth factor receptor inhibitor-induced cell death in squamous cell cancer.

Cancer Res 2007 Jan;67(2):727-34

Department of Hematology and Oncology, Martin-Luther University Halle, Halle, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-06-2162DOI Listing
January 2007

Epidermal growth factor receptor inhibition promotes desmosome assembly and strengthens intercellular adhesion in squamous cell carcinoma cells.

J Biol Chem 2004 Aug 16;279(35):37191-200. Epub 2004 Jun 16.

Departments of Pathology and Dermatology, The Robert H. Lurie Cancer Center, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, IL 60611, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M405123200DOI Listing
August 2004