Jochen Genschel

Jochen Genschel

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Jochen Genschel

Jochen Genschel

Publications by authors named "Jochen Genschel"

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11Publications

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Interaction of proliferating cell nuclear antigen with PMS2 is required for MutLα activation and function in mismatch repair.

Proc Natl Acad Sci U S A 2017 05 24;114(19):4930-4935. Epub 2017 Apr 24.

Department of Biochemistry, Duke University Medical Center, Durham, NC 27710;

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http://dx.doi.org/10.1073/pnas.1702561114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441711PMC
May 2017

PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance.

Proc Natl Acad Sci U S A 2010 Jul 12;107(30):13384-9. Epub 2010 Jul 12.

Department of Cell Biology, and Cancer Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1073/pnas.1008589107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922181PMC
July 2010

MutLalpha and proliferating cell nuclear antigen share binding sites on MutSbeta.

J Biol Chem 2010 Apr 12;285(15):11730-9. Epub 2010 Feb 12.

Department of Biochemistry, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1074/jbc.M110.104125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857047PMC
April 2010

Functions of MutLalpha, replication protein A (RPA), and HMGB1 in 5'-directed mismatch repair.

J Biol Chem 2009 Aug 10;284(32):21536-44. Epub 2009 Jun 10.

Department of Biochemistry, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1074/jbc.M109.021287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755878PMC
August 2009

A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair.

Proc Natl Acad Sci U S A 2009 May 6;106(21):8495-500. Epub 2009 May 6.

Department of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1073/pnas.0903654106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677980PMC
May 2009

Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair.

Proc Natl Acad Sci U S A 2008 Nov 29;105(44):16906-11. Epub 2008 Oct 29.

Department of Microbiology, University of California, Davis, CA 95616, USA.

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http://dx.doi.org/10.1073/pnas.0809380105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579351PMC
November 2008

Analysis of the excision step in human DNA mismatch repair.

Methods Enzymol 2006 ;408:273-84

Department of Biochemistry, Duke University Medical Center, Durham, North Carolina, USA.

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http://dx.doi.org/10.1016/S0076-6879(06)08017-7DOI Listing
February 2007

A defined human system that supports bidirectional mismatch-provoked excision.

Mol Cell 2004 Jul;15(1):31-41

Howard Hughes Medical Institute, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.molcel.2004.06.016DOI Listing
July 2004

Mechanism of 5'-directed excision in human mismatch repair.

Mol Cell 2003 Nov;12(5):1077-86

Department of Biochemistry, Box 3711, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/s1097-2765(03)00428-3DOI Listing
November 2003

Human exonuclease I is required for 5' and 3' mismatch repair.

J Biol Chem 2002 Apr 24;277(15):13302-11. Epub 2002 Jan 24.

Department of Biochemistry, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1074/jbc.M111854200DOI Listing
April 2002