Dr. Joao Rodrigues, PhD - Centro de Química da Madeira/University of Madeira - Director

Dr. Joao Rodrigues

PhD

Centro de Química da Madeira/University of Madeira

Director

Funchal, Madeira Island | Portugal

ORCID logohttps://orcid.org/0000-0003-4552-1953

Dr. Joao Rodrigues, PhD - Centro de Química da Madeira/University of Madeira - Director

Dr. Joao Rodrigues

PhD
Introduction

Primary Affiliation: Centro de Química da Madeira/University of Madeira - Funchal, Madeira Island , Portugal

Metrics

94

Publications

269

Profile Views

194

Reads

166

PubMed Central Citations

Experience
Centro de Química da Madeira
Scientific Director
Universidade da Madeira
Assistant Professor
Top co-authors
Yulin Li
Yulin Li

The Key Laboratory of Pathobiology

9
Dina Maciel
Dina Maciel

CQM - Centro de Química da Madeira

8
Xiangyang Shi
Xiangyang Shi

State Key Laboratory for Modification of Chemical Fibers and Polymer Materials

8
Jose L Santos
Jose L Santos

Laboratório de Termodinâmica de Proteínas

7
Rita Castro
Rita Castro

Centro de Patogénese Molecular

5
Pedro L Granja
Pedro L Granja

i3S - Instituto de Investigação e Inovação em Saúde

4

Publications

94Publications

194Reads

166PubMed Central Citations

Poly(alkylidenimine) Dendrimers Functionalized with the Organometallic Moiety [Ru(η⁵-C₅H₅)(PPh₃)₂]⁺ as Promising Drugs Against -Resistant Cancer Cells and Human Mesenchymal Stem Cells.

Molecules 2018 Jun 17;23(6). Epub 2018 Jun 17.

CQM-Centro de Química da Madeira, MMRG, Universidade da Madeira, Campus da Penteada, 9000-390 Funchal, Portugal.

View Article
June 2018
8 Reads
2.42 Impact Factor

Present drug-likeness filters in medicinal chemistry during the hit and lead optimization process: how far can they be simplified?

Drug Discov Today 2018 03 9;23(3):605-615. Epub 2018 Jan 9.

Medicinal Chemistry Division, Indian Institute of Integrative Medicine (Council of Scientific and Industrial Research), Canal Road, Jammu 180001, India. Electronic address:

View Article
March 2018
20 Reads
6.69 Impact Factor

Compound high-quality criteria: a new vision to guide the development of drugs, current situation.

Drug Discov Today 2016 Apr 21;21(4):573-84. Epub 2016 Jan 21.

Laboratoire de Chimie de Coordination du CNRS, 205 route de Narbonne, BP 44099, 31077 Toulouse Cedex 4, France; Université de Toulouse, UPS, INPT, 31077 Toulouse Cedex 4, France. Electronic address:

View Article
April 2016
3 Reads
1 PubMed Central Citation(source)
6.69 Impact Factor

Fine tuning of the pH-sensitivity of laponite-doxorubicin nanohybrids by polyelectrolyte multilayer coating.

Mater Sci Eng C Mater Biol Appl 2016 Mar 1;60:348-356. Epub 2015 Dec 1.

CQM - Centro de Química da Madeira, MMRG, Universidade da Madeira, Campus da Penteada, 9000-390 Funchal, Portugal. Electronic address:

View Article
March 2016
2 Reads
1 PubMed Central Citation(source)
3.09 Impact Factor

Self-assembled peptide nanoarchitectures: applications and future aspects.

Curr Top Med Chem 2015 ;15(13):1268-89

Department of Chemistry of Heterocyclic Compounds, State Scientific Institution "Institute for Single Crystals", National Academy of Science of Ukraine, Leninaave. 60, Kharkiv, 61001, Ukraine.

View Article
February 2016
19 Reads
1 PubMed Central Citation(source)
3.40 Impact Factor

Self-assembled organic nanostructures in medicinal chemistry: advances and applications.

Curr Top Med Chem 2015 ;15(13):1161

Centro de Quimica da Madeira, MMRG Universidade da Madeira Campus da Penteada 9020-105 Funchal Portugal.

View Article
February 2016
3.40 Impact Factor

Biodegradable Polymer Nanogels for Drug/Nucleic Acid Delivery.

Chem Rev 2015 Aug 11;115(16):8564-608. Epub 2015 Aug 11.

CQM-Centro de Química da Madeira, MMRG, Universidade da Madeira , Campus da Penteada 9000-390, Funchal, Portugal.

View Article
August 2015
4 Reads
8 PubMed Central Citations(source)
45.66 Impact Factor

PAMAM Dendrimer/pDNA Functionalized-Magnetic Iron Oxide Nanoparticles for Gene Delivery.

J Biomed Nanotechnol 2015 Aug;11(8):1370-84

View Article
August 2015
5 PubMed Central Citations(source)
5.34 Impact Factor

Octadecyl functionalized core-shell magnetic silica nanoparticle as a powerful nanocomposite sorbent to extract urinary volatile organic metabolites.

J Chromatogr A 2015 May 14;1393:18-25. Epub 2015 Mar 14.

CQM, Centro de Química da Madeira, Universidade da Madeira, 9000-390 Funchal, Portugal; Centro de Ciências Exatas e de Engenharia da Universidade da Madeira, Campus Universitário da Penteada, 9000-390 Funchal, Portugal. Electronic address:

View Article
May 2015
4 Reads
4.17 Impact Factor

Synthesis, characterization and solid-state photoluminescence studies of six alkoxy phenylene ethynylene dinuclear palladium(II) rods.

Dalton Trans 2015 Mar;44(9):4003-15

CQM - Centro de Química da Madeira, MMRG, Universidade da Madeira, Campus Universitário da Penteada, 9000-390 Funchal, Portugal.

View Article
March 2015
15 Reads
4.20 Impact Factor

RGD peptide-modified multifunctional dendrimer platform for drug encapsulation and targeted inhibition of cancer cells.

Colloids Surf B Biointerfaces 2015 Jan 11;125:82-9. Epub 2014 Nov 11.

CQM-Centro de Química da Madeira, Universidade da Madeira, Campus da Penteada, 9000-390 Funchal, Portugal; State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, People's Republic of China. Electronic address:

View Article
January 2015
40 Reads
6 PubMed Central Citations(source)
4.15 Impact Factor

Amphiphilic polymer-mediated formation of laponite-based nanohybrids with robust stability and pH sensitivity for anticancer drug delivery.

ACS Appl Mater Interfaces 2014 Oct 15;6(19):16687-95. Epub 2014 Sep 15.

CQM-Centro de Química da Madeira, MMRG, Universidade da Madeira , Campus Universitário da Penteada, 9020-105 Funchal, Portugal.

View Article
October 2014
3 Reads
2 PubMed Central Citations(source)
6.72 Impact Factor

Dendrimer-assisted formation of fluorescent nanogels for drug delivery and intracellular imaging.

Biomacromolecules 2014 Feb 28;15(2):492-9. Epub 2014 Jan 28.

CQM - Centro de Química da Madeira, MMRG, Universidade da Madeira , Campus Universitário da Penteada, 9020-105 Funchal, Portugal.

View Article
February 2014
7 Reads
3 PubMed Central Citations(source)
5.75 Impact Factor

Antitumor efficacy of doxorubicin-loaded laponite/alginate hybrid hydrogels.

Macromol Biosci 2014 Jan 21;14(1):110-20. Epub 2013 Aug 21.

CQM - Centro de Química da Madeira, Universidade da Madeira, Campus Universitário da Penteada, 9020-105, Funchal, Portugal.

View Article
January 2014
5 Reads
3.85 Impact Factor

pH-sensitive Laponite(®)/doxorubicin/alginate nanohybrids with improved anticancer efficacy.

Acta Biomater 2014 Jan 25;10(1):300-7. Epub 2013 Sep 25.

CQM - Centro de Química da Madeira, MMRG, Universidade da Madeira, Campus Universitário da Penteada, 9020-105 Funchal, Portugal.

View Article
January 2014
6 PubMed Central Citations(source)
6.03 Impact Factor

Redox-responsive alginate nanogels with enhanced anticancer cytotoxicity.

Biomacromolecules 2013 Sep 22;14(9):3140-6. Epub 2013 Aug 22.

CQM - Centro de Química da Madeira, MMRG, Universidade da Madeira, Campus Universitário da Penteada, 9020-105 Funchal, Portugal.

View Article
September 2013
1 Read
5 PubMed Central Citations(source)
5.75 Impact Factor

cis,cis,cis-(Acetato-κ(2) O,O')bis-[1,2-bis-(diphenyl-phosphan-yl)ethane-κ(2) P,P']ruthenium(II) 0.75-trifluoro-methane-sulfonate 0.25-chloride.

Acta Crystallogr Sect E Struct Rep Online 2013 Apr 23;69(Pt 4):m226. Epub 2013 Mar 23.

CQM - Centro de Química da Madeira, MMRG, Universidade da Madeira, Campus Universitário da Penteada, 9000-390 Funchal, Portugal.

View Article
April 2013

Insight into the role of N,N-dimethylaminoethyl methacrylate (DMAEMA) conjugation onto poly(ethylenimine): cell viability and gene transfection studies.

J Mater Sci Mater Med 2012 Dec 4;23(12):2967-80. Epub 2012 Sep 4.

CQM-Centro de Química da Madeira, MMRG, Universidade da Madeira, Campus da Penteada, 9000-390, Funchal, Portugal.

View Article
December 2012
4 Reads
2 PubMed Central Citations(source)
2.59 Impact Factor

Calcium phosphate-mediated gene delivery using simulated body fluid (SBF).

Int J Pharm 2012 Sep 1;434(1-2):199-208. Epub 2012 Jun 1.

CQM - Centro de Química da Madeira, MMRG, Universidade da Madeira, Campus Universitário da Penteada, 9000-390 Funchal, Portugal.

View Article
September 2012
2 Reads
5 PubMed Central Citations(source)
3.65 Impact Factor

Gene delivery using biodegradable polyelectrolyte microcapsules prepared through the layer-by-layer technique.

Biotechnol Prog 2012 Jul 20;28(4):1088-94. Epub 2012 Jul 20.

Centro de Química da Madeira (CQM), MMRG, Universidade da Madeira, Campus da Penteada, 9000-390 Funchal, Portugal.

View Article
July 2012
1 Read
1 PubMed Central Citation(source)

Injectable and biodegradable hydrogels: gelation, biodegradation and biomedical applications.

Chem Soc Rev 2012 Mar 24;41(6):2193-221. Epub 2011 Nov 24.

CQM-Centro de Química da Madeira, MMRG, Universidade da Madeira, Campus da Penteada 9020-105 Funchal, Portugal.

View Article
March 2012
23 Reads
67 PubMed Central Citations(source)
33.38 Impact Factor

Injectable hybrid laponite/alginate hydrogels for sustained release of methylene blue.

J Control Release 2011 Nov;152 Suppl 1:e55-7

Centro de Química da Madeira, Universidade da Madeira, Campus da Penteada 9000-390 Funchal, Portugal.

View Article
November 2011
4 Reads
7.70 Impact Factor

Non-viral gene delivery to mesenchymal stem cells: methods, strategies and application in bone tissue engineering and regeneration.

Curr Gene Ther 2011 Feb;11(1):46-57

CQM-Centro de Química da Madeira, MMRG, Universidade da Madeira, Campus Universitário da Penteada, Funchal, Portugal.

View Article
February 2011
2 Reads
19 PubMed Central Citations(source)
2.54 Impact Factor

Gene delivery into mesenchymal stem cells: a biomimetic approach using RGD nanoclusters based on poly(amidoamine) dendrimers.

Biomacromolecules 2011 Feb 6;12(2):472-81. Epub 2011 Jan 6.

CQM-Centro de Química da Madeira, MMRG, Universidade da Madeira, Campus Universitário da Penteada, Funchal, Portugal.

View Article
February 2011
4 Reads
6 PubMed Central Citations(source)
5.75 Impact Factor

How do nitriles compare with isoelectronic alkynyl groups in the electronic communication between iron centers bridged by phenylenebis- and -tris(nitrile) ligands? An electronic and crystal-structure study.

Inorg Chem 2011 Jan 30;50(1):114-24. Epub 2010 Nov 30.

Sciences Chimiques de Rennes, UMR CNRS No. 6226, Université de Rennes 1, 35042 Rennes Cedex, France.

View Article
January 2011
8 Reads
2 PubMed Central Citations(source)
4.76 Impact Factor

Receptor-mediated gene delivery using PAMAM dendrimers conjugated with peptides recognized by mesenchymal stem cells.

Mol Pharm 2010 Jun;7(3):763-74

CQM-Centro de Quimica da Madeira, MMRG, Departamento de Quimica, Universidade da Madeira, Campus Universitario da Penteada, 9000-390 Funchal, Portugal.

View Article
June 2010
4 Reads
9 PubMed Central Citations(source)
4.38 Impact Factor

Functionalization of poly(amidoamine) dendrimers with hydrophobic chains for improved gene delivery in mesenchymal stem cells.

J Control Release 2010 May 6;144(1):55-64. Epub 2010 Feb 6.

CQM - Centro de Química da Madeira, MMRG, Departamento de Química, Universidade da Madeira, Campus Universitário da Penteada, 9000-390 Funchal, Portugal.

View Article
May 2010
2 Reads
11 PubMed Central Citations(source)
7.70 Impact Factor

Visible-light photolytic synthesis of multinuclear and dendritic iron-nitrile cationic complexes.

Inorg Chem 2008 May 21;47(10):4421-8. Epub 2008 Mar 21.

Institut des Sciences Moléculaires, UMR CNRS No 5255, Université Bordeaux 1, 351 Cours de la Libération, 33405 Talence Cedex, France.

View Article
May 2008
7 Reads
1 PubMed Central Citation(source)
4.76 Impact Factor

4,4'-[Thio-phene-2,5-diylbis(ethyne-2,1-di-yl)]dibenzonitrile.

Acta Crystallogr Sect E Struct Rep Online 2008 Mar 29;64(Pt 4):o765-6. Epub 2008 Mar 29.

View Article
March 2008

Three 2,5-dialkoxy-1,4-diethynylbenzene derivatives.

Acta Crystallogr C 2008 Feb 12;64(Pt 2):o33-6. Epub 2008 Jan 12.

Centro de Química da Madeira, LQCMM/MMRG, Departamento de Química da Universidade da Madeira, 9000-390 Funchal, Portugal.

View Article
February 2008
0.33 Impact Factor
Top co-authors
Yulin Li
Yulin Li

The Key Laboratory of Pathobiology

9
Dina Maciel
Dina Maciel

CQM - Centro de Química da Madeira

8
Xiangyang Shi
Xiangyang Shi

State Key Laboratory for Modification of Chemical Fibers and Polymer Materials

8
Jose L Santos
Jose L Santos

Laboratório de Termodinâmica de Proteínas

7
Rita Castro
Rita Castro

Centro de Patogénese Molecular

5
Pedro L Granja
Pedro L Granja

i3S - Instituto de Investigação e Inovação em Saúde

4