Publications

Prevalence of lameness and leg lesions of lactating dairy cows housed in southern Brazil: Effects of housing systems.
J Dairy Sci 2018 Mar 21;101(3):2395-2405. Epub 2017 Dec 21.
Laboratório de Etologia Aplicada e Bem-Estar Animal (LETA), Departamento de Zootecnia e Desenvolvimento Rural, Universidade Federal de Santa Catarina, Rod. Admar Gonzaga, 1346, Itacorubi, 88034-001, Florianópolis, SC, Brazil. Electronic address:

The APE1 redox inhibitor E3330 reduces collective cell migration of human breast cancer cells and decreases chemoinvasion and colony formation when combined with docetaxel.
Chem Biol Drug Des 2017 Oct 3;90(4):561-571. Epub 2017 May 3.
Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Lisbon, Portugal.

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).
Redox Biol 2017 Oct 18;13:94-162. Epub 2017 May 18.
Molecular Cardiology, Center for Cardiology, Cardiology 1, University Medical Center Mainz, Mainz, Germany; DZHK (German Centre for Cardiovascular Research), partner site Rhine-Main, Mainz, Germany. Electronic address:

Triplet (FOLFOXIRI) versus doublet (FOLFOX or FOLFIRI) backbone chemotherapy as first-line treatment of metastatic colorectal cancer: A systematic review and meta-analysis.
Crit Rev Oncol Hematol 2017 Oct 25;118:54-62. Epub 2017 Aug 25.
Laboratório de Farmacologia Clínica e Terapêutica, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal; Clinical Pharmacology Unit, Instituto de Medicina Molecular, Lisboa, Portugal; Centro de Estudos de Medicina Baseada na Evidência, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.

Video-Based Surgical Learning: Improving Trainee Education and Preparation for Surgery.
J Surg Educ 2017 Oct 11. Epub 2017 Oct 11.
Surgical Sciences Research Domain, Life and Health Sciences Research Institute, ICVS/3B's, PT Government Associate Laboratory, The Clinic Academic Center, Braga, Association (2CA-Braga), School of Medicine, University of Minho, Braga, Portugal; Department of CUF Urology and Service of Urology, Hospital de Braga, Braga, Portugal.

[Analysis of the Cochrane Review: Omega-3 Fatty Acids for the Treatment of Dementia. Cochrane Database Syst Rev. 2016;4:CD009002.]
Acta Med Port 2017 Oct 31;30(10):671-674. Epub 2017 Oct 31.
Centro de Estudos de Medicina Baseada na Evidência. Faculdade de Medicina. Universidade de Lisboa. Lisboa. Portugal; Instituto de Medicina Preventiva e Saúde Pública. Faculdade de Medicina. Universidade de Lisboa. Lisboa. Portugal; Centro Colaborador Português da Rede Cochrane Iberoamericana. Faculdade de Medicina. Universidade de Lisboa. Lisboa. Portugal.

European Society of Anaesthesiology and European Board of Anaesthesiology guidelines for procedural sedation and analgesia in adults.
Eur J Anaesthesiol 2017 Sep 5. Epub 2017 Sep 5.
aFrom the Department of Anaesthesiology and Intensive Care Medicine, University Hospital of Cologne, Cologne, Germany (JH), Anaesthesiology Institute, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates (ML), Department of Clinical Sciences Malmö, Anaesthesiology and Intensive Care Medicine, Lund University Faculty of Medicine, Malmö, Sweden (JA), Centre for Evidence-Based Medicine, Faculty of Medicine, University of Lisbon, Lisbon, Portugal (JS,JC), Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples 'Federico II', Naples, Italy (EDR), Department of Anaesthesiology and Intensive Care, Hôpitaux Universitaires Paris Nord Val de Sein, Paris, France (DL), Clinical Department of Anaesthesiology and Intensive Care, University Medical Centre, Ljubljana, Slovenia (VNJ), Perioperative Medicine, Pain Therapy, RRS and Intensive Care Department, Anaesthesiology and Intensive Care University of Chieti-Pescara, Chieti, Italy (FP), Department of Anaesthesiology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands (MMRFS), Anesthésie, Hôpital Jeanne de Flandre, Lille (FV), Fuchs-Buder T. Department of Anaesthesiology and Critical Carel, CHRU Nancy, University of Lorraine, Nancy, France (TFB); and Karl Landsteiner Institute for Anaesthesiology and Intensive Care Medicine, Vienna, Austria (RF) *Chairman of the ESA/EBA taskforce for procedural sedation and analgesia guidelines in adults. †Co-chairman of the ESA/EBA taskforce for procedural sedation and analgesia guidelines in adults.

Non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation and valvular heart disease: systematic review and meta-analysis.
Eur Heart J Cardiovasc Pharmacother 2017 Sep 6. Epub 2017 Sep 6.
Cardiology Department, Centro Cardiovascular da Universidade de Lisboa (CCUL), Centro Académico Médico de Lisboa (CAML), Faculdade de Medicina, Universidade de Lisboa, Portugal.

Cost-effectiveness of the 13-valent Pneumococcal Conjugate Vaccine in Children in Portugal.
Pediatr Infect Dis J 2017 Aug;36(8):782-787
From the *Católica Lisbon School of Business and Economics, Universidade Católica Portuguesa, Lisboa, Portugal; †Centro de Estudos de Medicina Baseada na Evidência, Faculdade de Medicina da, Universidade de Lisboa, Lisboa, Portugal; ‡Laboratório de Farmacologia Clínica e Terapêutica, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal; §Unidade de Farmacologia Clínica, Instituto de Medicina Molecular, Lisboa, Portugal; and ¶Unidade de Farmacologia Clínica, Centro Hospitalar Lisboa Central EPE, Lisboa, Portugal.

[Analysis of the Cochrane Review: Anti-vascular Endothelial Growth Factor for Prevention of Postoperative Vitreous Cavity Hemorrhage after Vitrectomy for Proliferative Diabetic Retinopathy. Cochrane Database Syst Rev. 2015;8:CD008214.]
Acta Med Port 2017 Aug 31;30(7-8):513-516. Epub 2017 Aug 31.
Centro de Estudos de Medicina Baseada na Evidência. Faculdade de Medicina. Universidade de Lisboa. Lisboa. Portugal; Cochrane Portugal. Lisboa. Portugal.

Placebo and nocebo responses in restless legs syndrome: A systematic review and meta-analysis.
Neurology 2017 Jun 10;88(23):2216-2224. Epub 2017 May 10.
From the Laboratory of Clinical Pharmacology and Therapeutics (M.A.S., G.S.D., R.C., F.B.R., R.M.F., D.A., J.C., J.J.F.), Portuguese Collaborating Center of the IberoAmerican Cochrane Network, Cochrane Portugal (G.S.D., R.M.F., J.C.), and Center for Evidence-Based Medicine (J.C.), Faculty of Medicine, University of Lisbon; Clinical Pharmacology Unit (M.A.S., G.S.D., R.C., F.B.R., R.M.F., D.A., J.C., J.J.F.), Instituto de Medicina Molecular, Lisbon, Portugal; Huntington's Disease Centre (F.B.R.), Institute of Neurology, University College London, UK; Parkinson's Disease and Movement Disorders Center (T.M.), Division of Neurology, Department of Medicine, The Ottawa Hospital Research Institute, University of Ottawa, Canada; Paracelsus-Elena Klinik (C.T.), Center of Parkinsonism and Movement Disorders, Kassel; and the Department of Neurosurgery (C.T.), University Medical Center, Göttingen, Germany.

Impact of Routine Fractional Flow Reserve on Management Decision and 1-Year Clinical Outcome of Patients With Acute Coronary Syndromes: PRIME-FFR (Insights From the POST-IT [Portuguese Study on the Evaluation of FFR-Guided Treatment of Coronary Disease] and R3F [French FFR Registry] Integrated Multicenter Registries - Implementation of FFR [Fractional Flow Reserve] in Routine Practice).
Circ Cardiovasc Interv 2017 Jun;10(6)
From the Department of Cardiology, University Hospital, Lille, France (E.V.B., F.V.); INSERM U1011, Lille-II-University, France (E.V.B., F.V.); Hospital Fernando da Fonseca, Amadora, Portugal (S.-B.B.); Hospital de Santa Cruz - CHLO, Carnaxide, Portugal (L.R.); Statistical Department, St. Jude Medical Inc, St Paul, MN (J.H.); Hôpital Louis Pradel, Lyon, France (G.R.); INSERM 1060 CARMEN, Claude Bernard University Lyon, France (G.R.); Centro Hospitalar Vila Nova de Gaia, Portugal (L.S.); Clinique Sainte Clotilde, Saint Denis de la Réunion, France (C.P.); Hospital Santa Marta - Centro Hospitalar Lisboa Central, Lisboa, Portugal (R.R.); CHU La Timone, Marseille, France (T.C.); Hospital Garcia de Orta, Almada, Portugal (R.C.); CHU Mondor, Créteil, France (E.T.); Centro Hospitalar Universitário Coimbra, Portugal (E.J.); CH d'Annecy, France (L.B.); Hospital Divino Espirito Santo, Ponta Delgada, Portugal (C.M.); C.H.I.T.S. Hôpital Sainte Musse, Toulon, France (D.B.); Hospital Geral dos Covões - Centro Hospitalar Coimbra, Portugal (M.C.); Centre Hospitalier Haguenau, France (M.H.); Hospital Santa Maria - Centro Hospitalar Lisboa Norte, Portugal (E.O.); Hôpital de la Croix-Rousse, Lyon, France (C.B.); Hospital de Braga, Portugal (J.C.); Institut Pasteur de Lille-INSERM, France (J.D.); Hospital São Teotónio, Viseu, Portugal (J.P.); Hôpital Lariboisière, Paris, France (G.S.); Centro Hospitalar Setúbal, Portugal (N.F.); Centre Hospitalier Valence, France (C.B.); Hospital Santo André - Centro Hospitalar Leiria-Pombal, Portugal (J.G.); Hôpital Albert Schweizer, Colmar, France (N.L.); Hospital Dr. Nélio Mendonça, Funchal, Portugal (B.S.); Centre Hospitalier La Durance, Avignon, France (P.B.); Hospital Geral Santo António - Centro Hospitalar do Porto, Portugal (M.-J.S.); Centre Hospitalier Amiens Sud, Amiens, France (L.L.); Centro Hospitalar São João, Porto, Portugal (J.C.S.); Centro Hospitalar Tâmega e Sousa, Penafiel, Portugal (A.R.); Centro Hospitalar Trás-os-Montes e Alto Douro - Unidade Hospitalar Vila Real, Portugal (L.S.); Hospital Espírito Santo, Évora, Portugal (R.F.); and Hopital Privé d'Antony, France (P.D.).

[Analysis of the Cochrane Review: Pharmacotherapy for Hyperuricemia in Hypertensive Patients. Cochrane Database Syst Rev. 2017;4:CD008652.]
Acta Med Port 2017 May 31;30(5):356-360. Epub 2017 May 31.
Centro de Estudos de Medicina Baseada na Evidência. Faculdade de Medicina. Universidade de Lisboa. Lisboa. Portugal. Centro Colaborador Português da Rede Cochrane Iberoamericana. Lisboa. Portugal.

[Analysis of the Cochrane Review: Topical Treatments for Scalp Psoriasis. Cochrane Database Syst Rev. 2016;2:CD009687].
Acta Med Port 2017 Mar 31;30(3):163-168. Epub 2017 Mar 31.
Centro de Estudos de Medicina Baseada na Evidência. Faculdade de Medicina. Universidade de Lisboa. Lisboa. Portugal. Centro Colaborador Português da Rede Cochrane Iberoamericana. Lisboa. Portugal.

Chemical and structural characterization of Pholiota nameko extracts with biological properties.
Food Chem 2017 Feb 11;216:176-85. Epub 2016 Aug 11.
Universidade Católica Portuguesa, CBQF - Centro de Biotecnologia e Química Fina - Laboratório Associado, Escola Superior de Biotecnologia, Rua Arquitecto Lobão Vital, Apartado 2511, 4202-401 Porto, Portugal.

[Analysis of the Cochrane Review: Non-medical Prescribing versus Medical Prescribing for Acute and Chronic Disease Management in Primary and Secondary Care. Cochrane Database Syst Rev. 2016;11:CD011227.]
Acta Med Port 2017 Jan 31;30(1):7-11. Epub 2017 Jan 31.
Centro de Estudos de Medicina Baseada na Evidência. Faculdade de Medicina. Universidade de Lisboa. Lisboa. Portugal; Centro Colaborador Português da Rede Cochrane Iberoamericana. Lisboa. Portugal.


Room temperature aqueous self-assembly of poly(ethylene glycol)-poly(4-vinyl pyridine) block copolymers: From spherical to worm-like micelles.
Colloids Surf B Biointerfaces 2016 Sep 10;145:447-453. Epub 2016 May 10.
CEMUC-Department of Chemical Engineering, University of Coimbra, Polo II, Rua Sílvio Lima, 3030-790 Coimbra, Portugal. Electronic address:

[Analysis of the Cochrane Review: Portion, Package or Tableware Size for Changing Selection and Consumption of Food, Alcohol and Tobacco. Cochrane Database Syst Rev. 2015;09: CD011045.]
Acta Med Port 2016 Aug 31;29(7-8):421-424. Epub 2016 Aug 31.
Centro de Estudos de Medicina Baseada na Evidência. Faculdade de Medicina. Universidade de Lisboa. Lisboa. Portugal. Centro Colaborador Português da Rede Cochrane Ameroamerica. Lisboa. Portugal. Portugal.

[Pulmonary Embolism in Portugal: Epidemiology and In-Hospital Mortality].
Acta Med Port 2016 Aug 31;29(7-8):432-440. Epub 2016 Aug 31.
Centro de Estudos de Medicina Baseada na Evidência. Faculdade de Medicina. Universidade de Lisboa. Lisboa. Portugal. Laboratório de Farmacologia Clínica e Terapêutica. Faculdade de Medicina. Universidade de Lisboa. Lisboa. Portugal. Unidade de Farmacologia Clínica. Centro Hospitalar Lisboa Central. Lisboa. Portugal. Portugal.

Impact of Routine Fractional Flow Reserve Evaluation During Coronary Angiography on Management Strategy and Clinical Outcome: One-Year Results of the POST-IT.
Circ Cardiovasc Interv 2016 Jul;9(7)
From the Cardiology Department, Hospital Prof. Doutor Fernando Fonseca, Amadora, Portugal (S.B.B.); Cardiology Department, Hospital Santa Cruz, CHLO, Carnaxide, Portugal (L.R.); Cardiology Department, Centro Hospitalar Vila Nova de Gaia, Portugal (L.S.); Cardiology Department, Hospital Santa Marta, Centro Hospitalar Lisboa Central, Portugal (R.R.); Cardiology Department, Hospital Garcia de Orta, Almada, Portugal (R.C.); Cardiology Department, Centro Hospitalar e Universitário de Coimbra, Portugal (E.J.); Cardiology Department, Hospital Divino Espirito Santo, Ponta Delgada, Portugal (C.M.); Unidade de Intervenção Cardiovascular, Hospital Geral do Centro Hospitalar e Universitário de Coimbra, Portugal (M.C.); Cardiology Department, Hospital Santa Maria, Centro Hospitalar Lisboa Norte, Portugal (E.O.); Cardiology Department, Hospital de Braga, Portugal (J.C.); Cardiology Department, Centro Hospitalar Tondela-Viseu, Viseu, Portugal (J.P.); Cardiology Department, Centro Hospitalar Setúbal, Portugal (N.F.); Cardiology Department, Hospital Santo André, Centro Hospitalar Leiria-Pombal, Portugal (J.G.); Cardiology Department, Hospital Dr. Nélio Mendonça, Funchal, Portugal (B.S.); Cardiology Department, Hospital Geral Santo António, Centro Hospitalar do Porto, Portugal (J.S.); Cardiology Department, Centro Hospitalar São João, Porto, Portugal (J.S.); Cardiology Department, Centro Hospitalar Tâmega e Sousa, Penafiel, Portugal (A.R.); Cardiology Department, Centro Hospitalar Trás-os-Montes e Alto Douro, Unidade Hospitalar Vila Real, Portugal (L.S.); and Cardiology Department, Hospital Espírito Santo, Évora, Portugal (R.F.).

Half-dose photodynamic therapy for chronic central serous chorioretinopathy: Efficacy and safety outcomes in real world.
Photodiagnosis Photodyn Ther 2016 Jun 26;14:173-7. Epub 2016 Apr 26.
Consultant Ophthalmologist. Centro Hospitalar Vila Nova de Gaia/Espinho Department of Ophthalmology, Vila Nova de Gaia, Portugal; Head of Department. Centro Hospitalar Vila Nova de Gaia/Espinho Department of Ophthalmology, Vila Nova de Gaia, Portugal.

Stroke and Transient Ischemic Attack in Takayasu's Arteritis: A Systematic Review and Meta-analysis.
J Stroke Cerebrovasc Dis 2016 Apr 13;25(4):781-91. Epub 2016 Jan 13.
Center for Evidence Based Medicine, Faculty of Medicine, University of Lisbon, Lisbon, Portugal; Portuguese Collaborating Center of the IberoAmerican Cochrane Network, Faculty of Medicine, University of Lisbon, Lisbon, Portugal; Clinical Pharmacology Unit, Instituto de Medicina Molecular, Lisbon, Portugal.

Endovascular treatment versus medical care alone for ischaemic stroke: systematic review and meta-analysis.
BMJ 2016 Apr 18;353:i1754. Epub 2016 Apr 18.
Laboratory of Clinical Pharmacology and Therapeutics, Faculty of Medicine, University of Lisbon, Av Prof Egas Moniz 1649-035, Lisbon, Portugal Clinical Pharmacology Unit, Instituto de Medicina Molecular, Lisbon, Portugal Center for Evidence-Based Medicine, Faculty of Medicine, University of Lisbon, Portugal Portuguese Collaborating Center of the IberoAmerican Cochrane Network, Faculty of Medicine, University of Lisbon, Portugal.

Ochratoxin A-induced cytotoxicity, genotoxicity and reactive oxygen species in kidney cells: An integrative approach of complementary endpoints.
Food Chem Toxicol 2016 Jan 2;87:65-76. Epub 2015 Dec 2.
Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Professor Gama Pinto, 1649-003 Lisboa, Portugal.

[Analysis of the Cochrane Review: Incentives for Smoking Cessation. Cochrane Database Syst Rev. 2015;5:CD004307].
Acta Med Port 2016 Jan 29;29(1):12-4. Epub 2016 Jan 29.
Centro de Estudos de Medicina Baseada na Evidência. Faculdade de Medicina. Universidade de Lisboa. Lisboa. Portugal. Cochrane Portugal. Lisboa. Portugal. Laboratório de Farmacologia Clínica e Terapêutica. Faculdade Medicina. Universidade de Lisboa. Portugal.

Cochrane Corner: Colchicine in acute and recurrent pericarditis.
Rev Port Cardiol 2015 Nov 23;34(11):697-9. Epub 2015 Oct 23.
Laboratório de Farmacologia Clínica e Terapêutica, Faculdade de Medicina da Universidade de Lisboa, Portugal; Unidade de Farmacologia Clínica, Instituto de Medicina Molecular, Lisboa, Portugal; Centro de Estudos de Medicina Baseada na Evidência, Faculdade de Medicina da Universidade de Lisboa, Portugal; Centro Colaborador Português da Rede Cochrane Iberoamericana, Lisboa, Portugal.

Technologies that affect the weaning rate in beef cattle production systems.
Trop Anim Health Prod 2015 Oct 6;47(7):1255-60. Epub 2015 Jun 6.
Center for Studies and Research in Agribusiness - CEPAN. Núcleo de Estudos em Sistemas de Produção de Bovinos de Corte e Cadeia Produtiva - NESPRO, Federal University of Rio Grande do Sul - UFRGS, Ave. Bento Gonçalves 7712, 91540-000, Porto Alegre, RS, Brazil.

Non-vitamin K antagonist oral anticoagulants and major bleeding-related fatality in patients with atrial fibrillation and venous thromboembolism: a systematic review and meta-analysis.
Heart 2015 Aug 2;101(15):1204-11. Epub 2015 Jun 2.
Laboratory of Clinical Pharmacology and Therapeutics, Faculty of Medicine, University of Lisbon, Lisbon, Portugal Clinical Pharmacology Unit, Instituto de Medicina Molecular, Lisbon, Portugal Center for Evidence-Based Medicine, Faculty of Medicine, University of Lisbon, Lisbon, Portugal Portuguese Collaborating Center of the IberoAmerican Cochrane Network, Faculty of Medicine, University of Lisbon, Lisbon, Portugal.

A Pragmatic Strategy for the Evaluation and Management of Anterior Canal Benign Positional Vertigo.
Otol Neurotol 2016 08;37(7):e240
*Translational Clinical Physiology Unit, Faculty of Medicine, University of Lisbon †Health Sciences Institute, Portuguese Catholic University ‡Otolaryngology Department, Hospital de Santa Maria, Lisbon, Portugal §Neuro-Otology Department, Instituto de Investigaciones Neurológicas "Raúl Carrea" (FLENI), Buenos Aires, Argentina.

[Analysis of the Cochrane Review: Electronic Cigarettes for Smoking Cessation and Reduction. Cochrane Database Syst Rev. 2014,12: CD010216].
Acta Med Port 2015 Mar-Apr;28(2):145-7. Epub 2015 May 29.
Centro de Estudos de Medicina Baseada na Evidência. Faculdade de Medicina. Universidade de Lisboa. Lisboa. Portugal. Centro Colaborador Português da Rede Cochrane Iberoamericana. Lisboa. Portugal. Laboratório de Farmacologia Clínica e Terapêutica. Faculdade de Medicina. Universidade de Lisboa. Lisboa. Portugal.

The real identity of Leptodiranycthemera Werner, 1901 from Ecuador: a junior synonym of Oxyrhopuspetolarius (Linnaeus, 1758) (Serpentes, Dipsadidae).
Zookeys 2015 1(506):119-25. Epub 2015 Jun 1.
Museu Paraense Emílio Goeldi, Coordenação de Zoologia, Programa de Pós-Graduação em Zoologia, Av. Perimetral, 1901, Bairro Terra Firme, 66077-530, Belém, PA, Brazil ; Museu Paraense Emílio Goeldi, Coordenação de Zoologia, Av. Perimetral, 1901, Bairro Terra Firme, 66077-530, Belém, PA, Brazil.

[Analysis of the Cochrane Review: Interventions for Improving Upper Limb Function after Stroke. Cochrane Database Syst Rev. 2014,11:CD010820].
Acta Med Port 2015 Sep-Oct;28(5):551-3. Epub 2015 Oct 30.
Centro de Estudos de Medicina Baseada na Evidência. Faculdade de Medicina. Universidade de Lisboa. Lisboa. Portugal. Centro Colaborador Português da Rede Cochrane Iberoamericana. Lisboa. Portugal.



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