Publications by authors named "Joanne Stempak"

37Publications

Persistent Diarrhea in Patients With Crohn's Disease After Mucosal Healing Is Associated With Lower Diversity of the Intestinal Microbiome and Increased Dysbiosis.

Clin Gastroenterol Hepatol 2020 Mar 24. Epub 2020 Mar 24.

Division of Gastroenterology, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada; Zane Cohen Centre for Digestive Diseases, Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.cgh.2020.03.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511440PMC
March 2020

The Unsolved Link of Genetic Markers and Crohn's Disease Progression: A North American Cohort Experience.

Inflamm Bowel Dis 2019 08;25(9):1541-1549

Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital IBD Group, Division of Gastroenterology, Department of Medicine, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1093/ibd/izz016DOI Listing
August 2019

Stricturing and Fistulizing Crohn's Disease Is Associated with Anti-tumor Necrosis Factor-Induced Psoriasis in Patients with Inflammatory Bowel Disease.

Dig Dis Sci 2018 09 8;63(9):2430-2438. Epub 2018 May 8.

Division of Gastroenterology, Department of Medicine, Mount Sinai Hospital IBD Centre, University of Toronto, 441-600 University Avenue, Toronto, ON, M5G 1X5, Canada.

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http://dx.doi.org/10.1007/s10620-018-5096-2DOI Listing
September 2018

Therapeutic Drug Monitoring to Guide Infliximab Dose Adjustment is Associated with Better Endoscopic Outcomes than Clinical Decision Making Alone in Active Inflammatory Bowel Disease.

Inflamm Bowel Dis 2017 07;23(7):1202-1209

Division of Gastroenterology, Zane Cohen Centre for Digestive Diseases, Division of Gastroenterology, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/MIB.0000000000001126DOI Listing
July 2017

A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GM-CSF.

Gastroenterology 2016 10 1;151(4):710-723.e2. Epub 2016 Jul 1.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York; Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2016.06.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037012PMC
October 2016

TNFRSF1B Is Associated with ANCA in IBD.

Inflamm Bowel Dis 2016 06;22(6):1346-52

*Department of Medicine, F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California; †Mount Sinai Hospital, Toronto, Ontario, Canada; ‡The Susan and Leonard Feinstein IBD Clinical Center, East New York, New York; and §Institute for Translational Genomics and Population Science, Los Angeles Biomedical Research Institute and Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, California.

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http://dx.doi.org/10.1097/MIB.0000000000000771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288902PMC
June 2016

Microbiome Heterogeneity Characterizing Intestinal Tissue and Inflammatory Bowel Disease Phenotype.

Inflamm Bowel Dis 2016 Apr;22(4):807-16

*Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, ON, Canada; †Laboratory Medicine and Pathology, Mount Sinai Hospital, Toronto, ON, Canada; ‡Division of Gastroenterology, Department of Medicine, University of Toronto, Toronto, ON, Canada; and §Institute of Medical Science, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1097/MIB.0000000000000674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812575PMC
April 2016

Predictors of Outcome in Ulcerative Colitis.

Inflamm Bowel Dis 2015 Sep;21(9):2097-105

*Zane Cohen Centre for Digestive Diseases, Division of Gastroenterology, Mount Sinai Hospital, Toronto, ON, Canada; †Department of Gastroenterology, Rambam Health Care Campus, Haifa, Israel; ‡Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Neuroscience Research, Toronto, ON, Canada; §University of Toronto, Toronto, ON, Canada; ||Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada; and ¶Department of Surgery, Mount Sinai Hospital, Toronto, ON, Canada.

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http://dx.doi.org/10.1097/MIB.0000000000000466DOI Listing
September 2015

Higher Rates of Dose Optimisation for Infliximab Responders in Ulcerative Colitis than in Crohn's disease.

J Crohns Colitis 2015 Oct 26;9(10):830-6. Epub 2015 Jun 26.

Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital IBD Group, Toronto, ON, Canada Division of Gastroenterology, Department of Medicine, University of Toronto, Toronto, ON, Canada

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http://dx.doi.org/10.1093/ecco-jcc/jjv115DOI Listing
October 2015

Complex host genetics influence the microbiome in inflammatory bowel disease.

Genome Med 2014 2;6(12):107. Epub 2014 Dec 2.

Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142 USA ; Center for Computational and Integrative Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114 USA ; Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114 USA.

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http://dx.doi.org/10.1186/s13073-014-0107-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292994PMC
January 2015

Downregulation of expression of xenobiotic efflux genes is associated with pelvic pouch inflammation in ulcerative colitis.

Inflamm Bowel Dis 2014 Jul;20(7):1157-64

*Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada; †Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, ON, Canada; and ‡Division of Gastroenterology, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1097/MIB.0000000000000078DOI Listing
July 2014

Attachment, childhood abuse, and IBD-related quality of life and disease activity outcomes.

Inflamm Bowel Dis 2014 May;20(5):909-15

*Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Joseph and Wolf Lebovic Health Complex, Toronto, Canada; †Department of Psychiatry, and ‡Division of Gastroenterology, Mount Sinai Hospital, Toronto, Canada; and §Department of Psychology, Ryerson University, Toronto, Canada.

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http://dx.doi.org/10.1097/MIB.0000000000000015DOI Listing
May 2014

Effect of inflammatory bowel disease therapies on immunogenicity of Mycobacterium paratuberculosis proteins.

Scand J Gastroenterol 2014 Feb 21;49(2):157-63. Epub 2013 Nov 21.

Division of Infectious Diseases, Department of Medicine, University of British Columbia , Vancouver, BC , Canada.

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http://dx.doi.org/10.3109/00365521.2013.857713DOI Listing
February 2014

Serum antibodies associated with complex inflammatory bowel disease.

Inflamm Bowel Dis 2013 Jun;19(7):1499-505

The Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/MIB.0b013e318281f2a1DOI Listing
June 2013

Antimicrobial antibodies are associated with a Crohn's disease-like phenotype after ileal pouch-anal anastomosis.

Clin Gastroenterol Hepatol 2012 May 1;10(5):507-12.e1. Epub 2011 Oct 1.

Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.cgh.2011.09.016DOI Listing
May 2012

Distinct and overlapping genetic loci in Crohn's disease and ulcerative colitis: correlations with pathogenesis.

Inflamm Bowel Dis 2011 Sep 10;17(9):1936-42. Epub 2010 Dec 10.

Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital IBD Group, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/ibd.21579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164287PMC
September 2011

Common variants at five new loci associated with early-onset inflammatory bowel disease.

Authors:
Marcin Imielinski Robert N Baldassano Anne Griffiths Richard K Russell Vito Annese Marla Dubinsky Subra Kugathasan Jonathan P Bradfield Thomas D Walters Patrick Sleiman Cecilia E Kim Aleixo Muise Kai Wang Joseph T Glessner Shehzad Saeed Haitao Zhang Edward C Frackelton Cuiping Hou James H Flory George Otieno Rosetta M Chiavacci Robert Grundmeier Massimo Castro Anna Latiano Bruno Dallapiccola Joanne Stempak Debra J Abrams Kent Taylor Dermot McGovern Gary Silber Iwona Wrobel Antonio Quiros Jeffrey C Barrett Sarah Hansoul Dan L Nicolae Judy H Cho Richard H Duerr John D Rioux Steven R Brant Mark S Silverberg Kent D Taylor M Michael Barmuda Alain Bitton Themistocles Dassopoulos Lisa Wu Datta Todd Green Anne M Griffiths Emily O Kistner Michael T Murtha Miguel D Regueiro Jerome I Rotter L Philip Schumm A Hillary Steinhart Stephen R Targan Ramnik J Xavier Cécile Libioulle Cynthia Sandor Mark Lathrop Jacques Belaiche Olivier Dewit Ivo Gut Simon Heath Debby Laukens Myriam Mni Paul Rutgeerts André Van Gossum Diana Zelenika Denis Franchimont J P Hugot Martine de Vos Severine Vermeire Edouard Louis Lon R Cardon Carl A Anderson Hazel Drummond Elaine Nimmo Tariq Ahmad Natalie J Prescott Clive M Onnie Sheila A Fisher Jonathan Marchini Jilur Ghori Suzannah Bumpstead Rhian Gwillam Mark Tremelling Panos Delukas John Mansfield Derek Jewell Jack Satsangi Christopher G Mathew Miles Parkes Michel Georges Mark J Daly Melvin B Heyman George D Ferry Barbara Kirschner Jessica Lee Jonah Essers Richard Grand Michael Stephens Arie Levine David Piccoli John Van Limbergen Salvatore Cucchiara Dimitri S Monos Stephen L Guthery Lee Denson David C Wilson Straun F A Grant Mark Daly Mark S Silverberg Jack Satsangi Hakon Hakonarson

Nat Genet 2009 Dec 15;41(12):1335-40. Epub 2009 Nov 15.

Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ng.489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267927PMC
December 2009

Novel anti-glycan antibodies related to inflammatory bowel disease diagnosis and phenotype.

Am J Gastroenterol 2009 Jun 21;104(6):1426-34. Epub 2009 Apr 21.

Division of Gastroenterology, Mount Sinai Hospital, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/ajg.2009.79DOI Listing
June 2009

Attitudes toward genetic testing in patients with inflammatory bowel disease.

Eur J Gastroenterol Hepatol 2007 Apr;19(4):321-7

Inflammatory Bowel Disease Centre, Division of Gastroenterology, Mount Sinai Hospital, Toronto, Ontario, Canada.

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https://insights.ovid.com/crossref?an=00042737-200704000-000
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http://dx.doi.org/10.1097/MEG.0b013e328013e9a8DOI Listing
April 2007

Effects of folate deficiency on gene expression in the apoptosis and cancer pathways in colon cancer cells.

Carcinogenesis 2006 May 16;27(5):916-24. Epub 2005 Dec 16.

Institute of Medical Science, Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada M5S 1A8.

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http://dx.doi.org/10.1093/carcin/bgi312DOI Listing
May 2006

Cell and stage of transformation-specific effects of folate deficiency on methionine cycle intermediates and DNA methylation in an in vitro model.

Carcinogenesis 2005 May 3;26(5):981-90. Epub 2005 Feb 3.

Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada, M5S 1A8.

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http://academic.oup.com/carcin/article/26/5/981/2390846/Cell
Publisher Site
http://dx.doi.org/10.1093/carcin/bgi037DOI Listing
May 2005

The effect of dietary folate on genomic and p53-specific DNA methylation in rat colon.

Carcinogenesis 2003 Jan;24(1):81-90

Department of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.

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http://dx.doi.org/10.1093/carcin/24.1.81DOI Listing
January 2003