Joanne Ryan

Joanne Ryan

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The current status of blood epigenetic biomarkers for dementia.

Crit Rev Clin Lab Sci 2019 Nov 22;56(7):435-457. Epub 2019 Jul 22.

Department of Epidemiology and Preventive Medicine, Monash University , Melbourne , Australia.

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http://dx.doi.org/10.1080/10408363.2019.1639129DOI Listing
November 2019

Genetic resilience to Alzheimer's disease in APOE ε4 homozygotes: A systematic review.

Alzheimers Dement 2019 Sep 7. Epub 2019 Sep 7.

Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1016/j.jalz.2019.05.011DOI Listing
September 2019

Mental health trajectories among women in Australia as they age.

Aging Ment Health 2019 Jul 23;23(7):887-896. Epub 2018 May 23.

a School of Public Health and Preventive Medicine , Monash University , Melbourne , Australia.

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http://dx.doi.org/10.1080/13607863.2018.1474445DOI Listing
July 2019

Genetic and Epigenetic Regulation of the Serotonin Transporter Gene in Late-Life Depression.

J Geriatr Psychiatry Neurol 2019 Jul 21;32(4):175-177. Epub 2019 Apr 21.

2 INSERM, Université de Montpellier, Neuropsychiatry: Epidemiological and Clinical Research, Montpellier, France.

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http://dx.doi.org/10.1177/0891988719841725DOI Listing
July 2019

The epigenetic clock as a predictor of disease and mortality risk: a systematic review and meta-analysis.

Clin Epigenetics 2019 04 11;11(1):62. Epub 2019 Apr 11.

Department of Epidemiology and Preventive Medicine, Monash University, ASPREE, Level 5, The Alfred Centre, 99 Commercial Road, Melbourne, Victoria, 3004, Australia.

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http://dx.doi.org/10.1186/s13148-019-0656-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458841PMC
April 2019

A systematic review and meta-analysis of environmental, lifestyle and health factors associated with DNA methylation age.

J Gerontol A Biol Sci Med Sci 2019 Apr 17. Epub 2019 Apr 17.

School of Public Health and Preventive Medicine, Monash University, Melbourne, 3004, Victoria, Australia.

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https://academic.oup.com/biomedgerontology/advance-article/d
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http://dx.doi.org/10.1093/gerona/glz099DOI Listing
April 2019

Brain-derived neurotrophic factor DNA methylation mediates the association between neighborhood disadvantage and adolescent brain structure.

Psychiatry Res Neuroimaging 2019 Mar 24;285:51-57. Epub 2018 Dec 24.

Melbourne Neuropsychiatry Center, Department of Psychiatry, The University of Melbourne and Melbourne Health, Parkville, Victoria, Australia; Melbourne School of Psychological Sciences, The University of Melbourne, Melbourne, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.pscychresns.2018.12.012DOI Listing
March 2019

Cognitive Impairment, Sexual Activity and Physical Tenderness in Community-Dwelling Older Adults: A Cross-Sectional Exploration.

Gerontology 2018 23;64(6):589-602. Epub 2018 Aug 23.

Department of Epidemiology, Erasmus Medical Centre, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1159/000490560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262681PMC
January 2019

Association between DNA methylation of the KITLG gene and cortisol levels under stress: a replication study.

Stress 2019 01 9;22(1):162-168. Epub 2018 Oct 9.

a Department of Epidemiology and Preventive Medicine , Monash University , Melbourne , Australia.

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https://www.tandfonline.com/doi/full/10.1080/10253890.2018.1
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http://dx.doi.org/10.1080/10253890.2018.1519019DOI Listing
January 2019

Lifetime major depression and grey-matter volume

J Psychiatry Neurosci 2019 Jan;44(1):45-53

From INSERM, Univ Montpellier, Neuropsychiatry: Epidemiological and Clinical Research, Montpellier, France (Ancelin, Carrière, Artero, Ritchie, Ryan, Chaudieu); Monash Alfred Psychiatry Research Centre, Central Clinical School, Monash University and Alfred Hospital, Australia (Maller); Centre for Mental Health Research, Australian National University, Canberra, Australia (Maller, Meslin); General Electric Healthcare, Australia (Maller); Center for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom (Ritchie); and Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia (Ryan).

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http://dx.doi.org/10.1503/jpn.180026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306287PMC
January 2019

Effect of Aspirin on All-Cause Mortality in the Healthy Elderly.

N Engl J Med 2018 10 16;379(16):1519-1528. Epub 2018 Sep 16.

From the Department of Epidemiology and Preventive Medicine, Monash University (J.J.M., M.R.N., R.L.W., J.E.L., R.W., C.M.R., E.S., J.R., A.M.T., S.M.F., S.G.O., R.E.T., C.I.J.), Walter and Eliza Hall Institute of Medical Research (P.G.), and Baker Heart and Diabetes Institute (C.I.J.), Melbourne, and Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville (G.A.D.), VIC, Menzies Institute for Medical Research, University of Tasmania, Hobart (M.R.N.), the School of Public Health, Curtin University (C.M.R.), and the School of Medicine, Royal Perth Hospital, University of Western Australia (L.J.B.), Perth, College of Medicine, Biology, and Environment, Australian National University, Canberra, ACT (W.P.A.), and Discipline of General Practice, University of Adelaide, Adelaide, SA (N.S.) - all in Australia; Berman Center for Outcomes and Clinical Research, Hennepin Healthcare Research Institute (B.K., R.G., A.M.M.), and the Division of Geriatrics, Department of Medicine (A.M.M.), Hennepin Healthcare, HealthPartners Institute (K.L.M.), and the University of Minnesota (A.M.M.) - all in Minneapolis; the Department of Family Medicine and Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago (R.C.S.); the Center for Aging and Population Health, Department of Epidemiology, University of Pittsburgh, Pittsburgh (D.G.I., A.B.N.); Sticht Center on Aging and Alzheimer's Prevention, Section on Gerontology and Geriatric Medicine, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC (J.D.W.); the Department of Pharmacy Practice and Science, College of Pharmacy and Department of Family Medicine, Carver College of Medicine, University of Iowa, Iowa City (M.E.E.); and the Division of Geriatrics and Clinical Gerontology, National Institute on Aging, Bethesda, MD (B.R.).

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http://dx.doi.org/10.1056/NEJMoa1803955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433466PMC
October 2018

Effect of Aspirin on Disability-free Survival in the Healthy Elderly.

N Engl J Med 2018 10 16;379(16):1499-1508. Epub 2018 Sep 16.

From the Department of Epidemiology and Preventive Medicine, Monash University (J.J.M., R.L.W., M.R.N., C.M.R., R.W., E.S., J.E.L., A.M.T., S.M.F., S.G.O., R.E.T., C.I.J., J.R.), the Walter and Eliza Hall Institute of Medical Research (P.G.), and the Baker Heart and Diabetes Institute (C.I.J.), Melbourne, and the Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville (G.A.D.), VIC, Menzies Institute for Medical Research, University of Tasmania, Hobart (M.R.N.), the School of Public Health, Curtin University (C.M.R.), and the School of Medicine, Royal Perth Hospital, University of Western Australia (L.J.B.), Perth, the College of Medicine, Biology, and Environment, Australian National University, Canberra, ACT (W.P.A.), and Discipline of General Practice, University of Adelaide, Adelaide, SA (N.S.) - all in Australia; Berman Center for Outcomes and Clinical Research, Hennepin Healthcare Research Institute, Hennepin Healthcare (B.K., R.G., A.M.M.), HealthPartners Institute (K.L.M.), and the Division of Geriatrics, Department of Medicine, University of Minnesota (A.M.M.) - all in Minneapolis; the Department of Family Medicine and Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago (R.C.S.); the Center for Aging and Population Health, University of Pittsburgh, Pittsburgh (A.B.N.); Sticht Center on Aging and Alzheimer's Prevention, Section on Gerontology and Geriatric Medicine, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC (J.D.W.); the Department of Pharmacy Practice and Science, College of Pharmacy, and the Department of Family Medicine, Carver College of Medicine, University of Iowa, Iowa City (M.E.E.); and the Division of Geriatrics and Clinical Gerontology, National Institute on Aging, Bethesda, MD (B.R.).

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http://www.nejm.org/doi/10.1056/NEJMoa1800722
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http://dx.doi.org/10.1056/NEJMoa1800722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426126PMC
October 2018

Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly.

N Engl J Med 2018 10 16;379(16):1509-1518. Epub 2018 Sep 16.

From the Department of Epidemiology and Preventive Medicine, Monash University (J.J.M., R.W., R.L.W., A.M.T., M.R.N., C.M.R., J.E.L., E.S., S.M.F., S.G.O., R.E.T., C.I.J., J.R., E.M.W., S.E.M.), Baker Heart and Diabetes Institute (C.I.J.), the Department of Cardiology, St. Vincent's Hospital (M.J.), and the Department of Clinical Neurosciences, Central Clinical School, Monash University and Alfred Hospital (G.C.), Melbourne, and Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville (G.A.D.), VIC, Menzies Institute for Medical Research, University of Tasmania, Hobart (M.R.N.), the School of Public Health, Curtin University (C.M.R.), and the School of Medicine, Royal Perth Hospital, University of Western Australia (L.J.B.), Perth, the College of Medicine, Biology and Environment, Australian National University, Canberra, ACT (W.P.A.), and the Discipline of General Practice, University of Adelaide, Adelaide, SA (N.S.) - all in Australia; the Berman Center for Outcomes and Clinical Research, Hennepin Healthcare Research Institute, Hennepin Healthcare (B.K., R.G., A.M.M.), HealthPartners Institute (K.L.M.), and the Division of Geriatrics, Department of Medicine, Hennepin Healthcare and the University of Minnesota (A.M.M.), Minneapolis, and the School of Nursing, Minnesota State University, Mankato (D.B.) - all in Minnesota; the Department of Family Medicine and Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago (R.C.S.); Sticht Center on Aging and Alzheimer's Prevention, Section on Gerontology and Geriatric Medicine, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC (J.D.W.); the Department of Pharmacy Practice and Science, College of Pharmacy and Department of Family Medicine, Carver College of Medicine, University of Iowa, Iowa City (M.E.E.); the Division of Geriatrics and Clinical Gerontology, National Institute on Aging, Bethesda, MD (B.R.); the Department of Cardiovascular Medicine, Vascular Medicine Section, Cleveland Clinic, Cleveland (M.M.); the Center for Primary Care and Prevention, Brown University, Providence, RI (C.B.E.); and the University of Tennessee Health Science Center, Memphis (S.S.).

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http://www.nejm.org/doi/10.1056/NEJMoa1805819
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http://dx.doi.org/10.1056/NEJMoa1805819DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289056PMC
October 2018

Genotype-dependent associations between serotonin transporter gene (SLC6A4) DNA methylation and late-life depression.

BMC Psychiatry 2018 09 4;18(1):282. Epub 2018 Sep 4.

Cancer & Disease Epigenetics, Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, VIC, Australia.

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https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12888-018-1850-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122720PMC
September 2018

Updates on managing advanced breast cancer with palbociclib combination therapy.

Ther Adv Med Oncol 2018 3;10:1758835918793849. Epub 2018 Sep 3.

Pfizer Inc., New York, NY, USA.

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http://dx.doi.org/10.1177/1758835918793849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122240PMC
September 2018

Micro RNA as a potential blood-based epigenetic biomarker for Alzheimer's disease.

Clin Biochem 2018 Aug 6;58:5-14. Epub 2018 Jun 6.

Department of Epidemiology and Preventive Medicine, Monash University, Melbourne 3004, Victoria, Australia; Disease Epigenetics, Murdoch Childrens Research Institute, and The University of Melbourne, Parkville, 3052, Victoria, Australia; INSERM, U1061, Neuropsychiatrie, Recherche Clinique et Epidémiologique, Univ. Montpellier, Montpellier 34000, France.

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http://dx.doi.org/10.1016/j.clinbiochem.2018.05.020DOI Listing
August 2018

Time- and sex-dependent associations between prenatal alcohol exposure and placental global DNA methylation.

Epigenomics 2018 07 29;10(7):981-991. Epub 2018 Jun 29.

Environmental & Genetic Epidemiology Research, Murdoch Children's Research Institute, the Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.2217/epi-2017-0147DOI Listing
July 2018

Phenotypic Heterogeneity in Dementia: A Challenge for Epidemiology and Biomarker Studies.

Front Public Health 2018 19;6:181. Epub 2018 Jun 19.

Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, VIC, Australia.

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http://dx.doi.org/10.3389/fpubh.2018.00181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018385PMC
June 2018

The role of oxytocin receptor gene (OXTR) DNA methylation (DNAm) in human social and emotional functioning: a systematic narrative review.

BMC Psychiatry 2018 05 29;18(1):154. Epub 2018 May 29.

Deakin University Geelong, Centre for Social and Early Emotional Development, Faculty of Health, School of Psychology, 221 Burwood Highway, Burwood, VIC, 3125, Australia.

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http://dx.doi.org/10.1186/s12888-018-1740-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975530PMC
May 2018

DNA methylation and genetic variation of the angiotensin converting enzyme (ACE) in depression.

Psychoneuroendocrinology 2018 02 8;88:1-8. Epub 2017 Nov 8.

Cancer & Disease Epigenetics, Murdoch Children's Research Institute, Royal Children's Hospital & Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia; INSERM, U1061, Neuropsychiatrie, Recherche Clinique et Epidémiologique, Univ. Montpellier, Montpellier, France; Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.psyneuen.2017.11.003DOI Listing
February 2018

Blood DNA methylation as a potential biomarker of dementia: A systematic review.

Alzheimers Dement 2018 01 8;14(1):81-103. Epub 2017 Nov 8.

Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia; Disease Epigenetics, Murdoch Children's Research Institute, The University of Melbourne, Parkville, Victoria, Australia; INSERM, Neuropsychiatry: Epidemiological and Clinical Research, University of Montpellier, Montpellier, France. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2017.10.002DOI Listing
January 2018

Epigenetics: a missing link in understanding psychiatric disorders?

Lancet Psychiatry 2018 01;5(1):8-9

Murdoch Children's Research Institute and Department of Paediatrics, The University of Melbourne, Melbourne, Australia; Centre for Adolescent Health, Royal Children's Hospital, Parkville, Australia.

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http://dx.doi.org/10.1016/S2215-0366(17)30481-9DOI Listing
January 2018

Management of Older Patients With Metastatic Renal Cell Carcinoma Receiving Sunitinib: A Hypothetical, Illustrative Case Scenario.

J Adv Pract Oncol 2018 Jan-Feb;9(1):67-76. Epub 2018 Jan 1.

Duke Prostate Center, Durham, North Carolina.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296420PMC
January 2018

The effect of an adverse psychological environment on salivary cortisol levels in the elderly differs by genotype.

Neurobiol Stress 2017 Dec 22;7:38-46. Epub 2017 Mar 22.

Inserm, U1061, Montpellier, France; University of Montpellier, Montpellier, France; Disease Epigenetics Group, Murdoch Children's Research Institute and Department of Paediatrics, The University of Melbourne, Parkville, Australia; Department of Epidemiology and Preventative Medicine, School of Public Health and Preventative Medicine, Monash University, Prahran, Australia.

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http://dx.doi.org/10.1016/j.ynstr.2017.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369865PMC
December 2017

The Dangers of Direct-to-Consumer Genetic Testing for Alzheimer's Disease : Comment on "Personal Genomic Testing, Genetic Inheritance, and Uncertainty".

J Bioeth Inq 2017 12 13;14(4):585-587. Epub 2017 Nov 13.

School of Public Health & Preventive Medicine, Monash University, Level 5, The Alfred Centre, 99 Commercial Road, Melbourne, Victoria, 3004, Australia.

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http://dx.doi.org/10.1007/s11673-017-9817-6DOI Listing
December 2017

Cannabis use by women during pregnancy does not influence infant DNA methylation of the dopamine receptor DRD4.

Am J Drug Alcohol Abuse 2017 11 27;43(6):671-677. Epub 2017 Apr 27.

a Murdoch Childrens Research Institute, The University of Melbourne , Parkville , Victoria , Australia.

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http://dx.doi.org/10.1080/00952990.2017.1314488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706968PMC
November 2017

Pathogenic variants in the healthy elderly: unique ethical and practical challenges.

J Med Ethics 2017 10 24;43(10):714-722. Epub 2017 Mar 24.

Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, ASPREE - Monash University, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1136/medethics-2016-103967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629947PMC
October 2017

Investigating the epigenetic profile of the inflammatory gene IL-6 in late-life depression.

BMC Psychiatry 2017 10 25;17(1):354. Epub 2017 Oct 25.

Cancer & Disease Epigenetics, Murdoch Childrens Research Institute, Royal Children's Hospital & Department of Paediatrics, University of Melbourne, Parkville, VIC, 3052, Australia.

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http://dx.doi.org/10.1186/s12888-017-1515-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657056PMC
October 2017

Relationships Between Self-Reported and Observed Parenting Behaviour, Adolescent Disordered Eating Attitudes and Behaviours, and the 5-HTTLPR Polymorphism: Data From the Australian Temperament Project.

Eur Eat Disord Rev 2017 09 10;25(5):381-388. Epub 2017 Jul 10.

Psychological Sciences, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Parkville, VIC, Australia.

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http://doi.wiley.com/10.1002/erv.2530
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http://dx.doi.org/10.1002/erv.2530DOI Listing
September 2017

Role of the Advanced Practice Provider in Clinical Trials: Contributions to the Management of Patients Receiving Inotuzumab Ozogamicin.

J Adv Pract Oncol 2017 Sep-Oct;8(6):631-636. Epub 2017 Sep 1.

Dana Farber Cancer Institute, Boston, Massachusetts.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167080PMC
September 2017

Heterogeneity in HPA axis dysregulation and serotonergic vulnerability to depression.

Psychoneuroendocrinology 2017 03 5;77:90-94. Epub 2016 Dec 5.

Inserm, U1061, University Montpellier, Montpellier, France; Disease Epigenetics Group, Murdoch Children's Research Institute, and Department of Paediatrics, The University of Melbourne, Parkville, Australia; Department of Epidemiology and Preventative Medicine, School of Public Health and Preventative Medicine, Monash University, Prahran, Australia.

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http://dx.doi.org/10.1016/j.psyneuen.2016.11.016DOI Listing
March 2017

Does maternal mental well-being in pregnancy impact the early human epigenome?

Epigenomics 2017 03 31;9(3):313-332. Epub 2017 Jan 31.

Department of Cancer & Disease Epigenetics, Murdoch Childrens Research Institute, Royal Childrens Hospital, & Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.2217/epi-2016-0118DOI Listing
March 2017

Biological underpinnings of trauma and post-traumatic stress disorder: focusing on genetics and epigenetics.

Epigenomics 2016 11 30;8(11):1553-1569. Epub 2016 Sep 30.

Cancer & Disease Epigenetics Group, Murdoch Children's Research Institute, Royal Childrens Hospital, Parkville 3052, Victoria, Australia.

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http://dx.doi.org/10.2217/epi-2016-0083DOI Listing
November 2016

Common variants in CACNA1C and MDD susceptibility: A comprehensive meta-analysis.

Am J Med Genet B Neuropsychiatr Genet 2016 09 3;171(6):896-903. Epub 2016 Jun 3.

National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1002/ajmg.b.32466DOI Listing
September 2016

Common variants in FKBP5 gene and major depressive disorder (MDD) susceptibility: a comprehensive meta-analysis.

Sci Rep 2016 09 7;6:32687. Epub 2016 Sep 7.

National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences &Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 10005, China.

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http://dx.doi.org/10.1038/srep32687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013409PMC
September 2016

Palbociclib Plus Letrozole for the Treatment of Metastatic Breast Cancer: An Illustrative Case Scenario.

J Adv Pract Oncol 2016 Jul-Aug;7(5):550-561. Epub 2016 Jul 1.

1Community Hospital Oncology Physicians, Zionsville, Indiana; 2Pfizer Inc, New York, New York; 3Allegheny Health Network Cancer Institute, Pittsburgh, Pennsylvania.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737402PMC
July 2016

Meta-analysis indicates that SNP rs9939609 within FTO is not associated with major depressive disorder (MDD) in Asian population.

J Affect Disord 2016 Mar 31;193:27-30. Epub 2015 Dec 31.

School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2015.12.048DOI Listing
March 2016

GWAS-identified risk variants for major depressive disorder: Preliminary support for an association with late-life depressive symptoms and brain structural alterations.

Eur Neuropsychopharmacol 2016 Jan 9;26(1):113-125. Epub 2015 Sep 9.

Inserm, U1061, Montpellier F-34093; Université Montpellier, Montpellier F-34000, France.

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http://dx.doi.org/10.1016/j.euroneuro.2015.08.022DOI Listing
January 2016

Epigenetics and depressive disorders: a review of current progress and future directions.

Int J Epidemiol 2015 Aug 24;44(4):1364-87. Epub 2015 Feb 24.

Cancer & Disease Epigenetics, Murdoch Childrens Research Institute, & Department of Paediatrics, University of Melbourne, Parkville, VIC, Australia and Inserm U1061, Hopital La Colombiere & Universite Montpellier, Montpellier, France

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http://dx.doi.org/10.1093/ije/dyu273DOI Listing
August 2015

Involvement of GPR50 polymorphisms in depression: independent replication in a prospective elderly cohort.

Brain Behav 2015 Mar 8;5(3):e00313. Epub 2015 Feb 8.

Inserm, U1061 Montpellier, F-34093, France ; Univ Montpellier 1, U1061 Montpellier, France.

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http://dx.doi.org/10.1002/brb3.313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356842PMC
March 2015

A smartphone-enabled communication system to improve hospital communication: usage and perceptions of medical trainees and nurses on general internal medicine wards.

J Hosp Med 2015 Feb 29;10(2):83-9. Epub 2014 Oct 29.

Centre for Innovation in Complex Care, University Health Network, Toronto, Canada; Department of Medicine, University of Toronto, Toronto, Canada; Division of General Internal Medicine, University Health Network, Toronto, Canada.

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http://dx.doi.org/10.1002/jhm.2278DOI Listing
February 2015

Brain volumes in late life: gender, hormone treatment, and estrogen receptor variants.

Neurobiol Aging 2014 Mar 23;35(3):645-54. Epub 2013 Oct 23.

Inserm, U1061, Montpellier F-34093, Université Montpellier 1, Montpellier, France; Cancer & Disease Epigenetics Group, Murdoch Childrens Research Institute, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2013.09.026DOI Listing
March 2014

Postnatal stability, tissue, and time specific effects of AHRR methylation change in response to maternal smoking in pregnancy.

Epigenetics 2014 Mar 22;9(3):377-86. Epub 2013 Nov 22.

Cancer, Disease and Developmental Epigenetics; Murdoch Childrens Research Institute; Royal Children's Hospital; Parkville, VIC Australia; Department of Paediatrics; University of Melbourne; Parkville, VIC Australia.

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http://dx.doi.org/10.4161/epi.27248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053456PMC
March 2014

Estrogen receptor polymorphisms and incident dementia: the prospective 3C study.

Alzheimers Dement 2014 Jan 13;10(1):27-35. Epub 2013 Mar 13.

Inserm, U1061, Neuropsychiatry: Epidemiological and Clinical Research, Montpellier, France; Université Montpellier1, Montpellier, France.

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https://linkinghub.elsevier.com/retrieve/pii/S15525260130001
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http://dx.doi.org/10.1016/j.jalz.2012.12.008DOI Listing
January 2014

Lifelong estrogen exposure and memory in older postmenopausal women.

J Alzheimers Dis 2013 ;34(3):601-8

Primary Care Research Unit, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.

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http://dx.doi.org/10.3233/JAD-122062DOI Listing
December 2013

Prospective analysis of the association between estrogen receptor gene variants and the risk of cognitive decline in elderly women.

Eur Neuropsychopharmacol 2013 Dec 7;23(12):1763-8. Epub 2013 Aug 7.

Inserm, U1061, Neuropsychiatry: Epidemiological and Clinical Research, Montpellier F-34093, France; Université Montpellier1, Montpellier F-34000, France; Cancer & Disease Epigenetics, Murdoch Children's Research Institute, Flemington Road Parkville, 3052 Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.euroneuro.2013.06.003DOI Listing
December 2013

Lifetime endogenous reproductive factors and severe depressive symptoms in postmenopausal women: findings from the E3N cohort.

Menopause 2013 Nov;20(11):1154-63

From the 1U1018, Institut National de la Santé et de la Recherche Médicale, Center for Research in Epidemiology and Population Health, Villejuif Cedex, France; 2U1018, Université Paris-Sud, Villejuif Cedex, France; 3Gustave Roussy, Villejuif Cedex, France; 4U1061, Institut National de la Santé et de la Recherche Médicale, Université Montpellier, Montpellier, France; and 5Cancer and Disease Epigenetics, Murdoch Children's Research Institute, Parkville, Australia.

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http://dx.doi.org/10.1097/GME.0000000000000098DOI Listing
November 2013

Anxiety and mortality risk in community-dwelling elderly people.

Br J Psychiatry 2013 Sep 8;203(3):303-9. Epub 2013 Aug 8.

Isabelle Carrière, PhD, Inserm U1061 and University of Montpellier I, Montpellier, France; Joanne Ryan, PhD, Inserm U1061 and University of Montpellier I, Montpellier, France, and Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia; Joanna Norton, PhD, Jacqueline Scali, MSc, Inserm U1061 and University of Montpellier I, Montpellier, France; Robert Stewart, PhD, Institute of Psychiatry, King's College London, UK; Karen Ritchie, PhD, Inserm U1061 and University of Montpellier I, Montpellier, France, and Faculty of Medicine, Imperial College, St Mary's Hospital, London, UK; Marie Laure Ancelin, PhD, Inserm U1061 and University of Montpellier I, Montpellier, France.

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http://dx.doi.org/10.1192/bjp.bp.112.124685DOI Listing
September 2013

Polymorphisms of estrogen receptors and risk of depression: therapeutic implications.

Drugs 2012 Sep;72(13):1725-38

Inserm U1061, Montpellier, France.

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http://dx.doi.org/10.2165/11635960-000000000-00000DOI Listing
September 2012

Predictors of practice patterns for lymphedema care among oncology advanced practice nurses.

J Adv Pract Oncol 2012 Sep;3(5):307-18

New York University College of Nursing and College of Dentistry, New York, New York.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093356PMC
September 2012

Hormone levels and cognitive function in postmenopausal midlife women.

Neurobiol Aging 2012 Jul;33(7):1138-47

Department of Psychiatry and National Ageing Research Institute, The University of Melbourne, Parkville 3010, Victoria, Australia.

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http://dx.doi.org/10.1016/j.neurobiolaging.2012.04.011DOI Listing
July 2012

Low plasma testosterone and elevated carotid intima-media thickness: importance of low-grade inflammation in elderly men.

Atherosclerosis 2012 Jul 16;223(1):244-9. Epub 2012 May 16.

Center for Research in Epidemiology and Population Health, Hormones and Cardiovascular Disease, University Paris-Sud, UMR-S, Villejuif, France.

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http://dx.doi.org/10.1016/j.atherosclerosis.2012.05.009DOI Listing
July 2012

High level of plasma estradiol as a new predictor of ischemic arterial disease in older postmenopausal women: the three-city cohort study.

J Am Heart Assoc 2012 Jun 22;1(3):e001388. Epub 2012 Jun 22.

Centre for Research in Epidemiology and Population Health, Inserm Unit 1018, Hormones and Cardiovascular Disease, Villejuif, France (V.S., M.C., G.P.-B., P.-Y.S.) ; Université Paris-Sud, UMR-S 1018, Villejuif, France (V.S., M.C., P.D., P.-Y.S.).

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https://www.ahajournals.org/doi/10.1161/JAHA.112.001388
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http://dx.doi.org/10.1161/JAHA.112.001388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487322PMC
June 2012

Hormone levels and cognitive function in postmenopausal midlife women.

Neurobiol Aging 2012 Mar 16;33(3):617.e11-22. Epub 2010 Dec 16.

Department of Psychiatry and National Ageing Research Institute, The University of Melbourne, Parkville 3010, Victoria, Australia; INSERM, U888, Montpellier, F-34093, France; University Montpellier 1, Montpellier, F-34000, France.

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http://dx.doi.org/10.1016/j.neurobiolaging.2010.07.014DOI Listing
March 2012

Estrogen receptor alpha gene variants and major depressive episodes.

J Affect Disord 2012 Feb 3;136(3):1222-6. Epub 2011 Nov 3.

Inserm, U 1061, Hopital La Colombiere, and University Montpellier 1, Montpellier, F-34000 France.

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http://dx.doi.org/10.1016/j.jad.2011.10.010DOI Listing
February 2012

Estrogen receptor gene variants are associated with anxiety disorders in older women.

Psychoneuroendocrinology 2011 Nov 12;36(10):1582-6. Epub 2011 May 12.

Inserm, U1061, Nervous System Pathologies: Epidemiological and Clinical Research, Hôpital La Colombière, Montpellier, France.

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http://dx.doi.org/10.1016/j.psyneuen.2011.04.011DOI Listing
November 2011

Oestrogen receptor polymorphisms and late-life depression.

Br J Psychiatry 2011 Aug;199(2):126-31

Inserm U1061, Hôpital La Colombière, 39 Avenue Charles Flahault, BP 34493, 34093 Montpellier Cedex 5, France.

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http://dx.doi.org/10.1192/bjp.bp.111.091751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623726PMC
August 2011

Executive functions in recently postmenopausal women: absence of strong association with serum gonadal steroids.

Brain Res 2011 Mar 2;1379:199-205. Epub 2010 Nov 2.

Department of Psychiatry, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1016/j.brainres.2010.10.093DOI Listing
March 2011

A prospective study of hormone therapy and depression in community-dwelling elderly women: the Three City Study.

J Clin Psychiatry 2010 Dec 10;71(12):1673-9. Epub 2010 Aug 10.

Institut National de la Santé et de la Recherche Médicale U888, Montpellier, France.

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http://dx.doi.org/10.4088/JCP.09m05188bluDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078521PMC
December 2010

The wnt target jagged-1 mediates the activation of notch signaling by progastrin in human colorectal cancer cells.

Cancer Res 2009 Aug 21;69(15):6065-73. Epub 2009 Jul 21.

Centre National de la Recherche Scientifique UMR5203, Institut National de la Sante et de la Recherche Medicale U661, University of Montpellier I, Montpellier, France.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-2409DOI Listing
August 2009

A prospective study of hormonal treatment and anxiety disorders in community-dwelling elderly women (the Esprit Study).

J Affect Disord 2009 May 11;115(1-2):274-9. Epub 2008 Oct 11.

Inserm, U888, Montpellier, F-34093 France.

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http://dx.doi.org/10.1016/j.jad.2008.09.007DOI Listing
May 2009

Life-time estrogen exposure and cognitive functioning in later life.

Psychoneuroendocrinology 2009 Feb 22;34(2):287-98. Epub 2008 Oct 22.

Inserm, U888, Montpellier F-34093, France.

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http://linkinghub.elsevier.com/retrieve/pii/S030645300800250
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http://dx.doi.org/10.1016/j.psyneuen.2008.09.008DOI Listing
February 2009

Lifetime hormonal factors may predict late-life depression in women.

Int Psychogeriatr 2008 Dec 5;20(6):1203-18. Epub 2008 Jun 5.

Inserm, U888, Montpellier, F-34093 France.

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http://dx.doi.org/10.1017/S1041610208007412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612035PMC
December 2008

New trisubstituted 1,2,4-triazole derivatives as potent ghrelin receptor antagonists. 3. Synthesis and pharmacological in vitro and in vivo evaluations.

J Med Chem 2008 Feb 15;51(3):689-93. Epub 2008 Jan 15.

Institut des Biomolécules Max Mousseron, UMR 5247, CNRS, Universités Montpellier 1, Montpellier 2, Montpellier Cedex 5, France.

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http://dx.doi.org/10.1021/jm701292sDOI Listing
February 2008

Trisubstituted 1,2,4-triazoles as ligands for the ghrelin receptor: on the significance of the orientation and substitution at position 3.

Bioorg Med Chem Lett 2008 Jan 4;18(1):164-8. Epub 2007 Nov 4.

Institut des Biomolécules Max Mousseron, UMR 5247, CNRS-Université Montpellier I, BP 14491, Faculté de Pharmacie, 15 avenue Charles Flahault, 34093 Montpellier Cedex 5, France.

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http://dx.doi.org/10.1016/j.bmcl.2007.10.113DOI Listing
January 2008

Late-life depression and mortality: influence of gender and antidepressant use.

Br J Psychiatry 2008 Jan;192(1):12-8

Institut National de la Santé et de la Recherche Médicale (INSERM) U888, University of Montpellier, France.

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http://dx.doi.org/10.1192/bjp.bp.107.039164DOI Listing
January 2008

Toward potent ghrelin receptor ligands based on trisubstituted 1,2,4-triazole structure. 2. Synthesis and pharmacological in vitro and in vivo evaluations.

J Med Chem 2007 Nov 10;50(23):5790-806. Epub 2007 Oct 10.

Institut des Biomolécules Max Mousseron, UMR 5247, CNRS, Université Montpellier I et Université Montpellier II, BP 14491, Faculté de Pharmacie, 15 Avenue Charles Flahault, 34093 Montpellier Cedex 5, France.

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http://dx.doi.org/10.1021/jm0704550DOI Listing
November 2007

Recent developments in ghrelin receptor ligands.

ChemMedChem 2007 Sep;2(9):1242-59

Institut des Biomolécules Max Mousseron, Faculté de Pharmacie, 15 avenue Charles Flahault, BP 1441, 34093 Montpellier Cedex, France.

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http://dx.doi.org/10.1002/cmdc.200700015DOI Listing
September 2007

Synthesis and pharmacological in vitro and in vivo evaluations of novel triazole derivatives as ligands of the ghrelin receptor. 1.

J Med Chem 2007 Apr 22;50(8):1939-57. Epub 2007 Mar 22.

Institut des Biomolécules Max Mousseron, UMR 5247, CNRS-Universités Montpellier I et II, BP. 14491, Faculté de Pharmacie, 15 avenue Charles Flahault, 34093 Montpellier Cedex 5, France.

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http://dx.doi.org/10.1021/jm070024hDOI Listing
April 2007

DNA-methylation-dependent alterations of claudin-4 expression in human bladder carcinoma.

Carcinogenesis 2007 Feb 8;28(2):246-58. Epub 2006 Jul 8.

CNRS UMR5203, INSERM U661, Université Montpellier I, and Service d'Anatomo-pathologie, CHU Groupe Hospitalisation Carémeau, Nîmes, France.

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http://dx.doi.org/10.1093/carcin/bgl120DOI Listing
February 2007

Regulation of ERK1/2 activity by ghrelin-activated growth hormone secretagogue receptor 1A involves a PLC/PKCvarepsilon pathway.

Br J Pharmacol 2006 Jun;148(3):350-65

Laboratoire des Aminoacides, Peptides et Protéines (LAPP), CNRS UMR-5810, UMI et UMII, UFR Pharmacie, 15 avenue Charles Flahault, Montpellier 34093, Cedex 5, France.

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http://dx.doi.org/10.1038/sj.bjp.0706727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751558PMC
June 2006

Cellular munc18c levels can modulate glucose transport rate and GLUT4 translocation in 3T3L1 cells.

FEBS Lett 2002 Sep;528(1-3):154-60

CSIRO Health Sciences and Nutrition, 343 Royal Parade, Parkville, Vic. 3052, Australia.

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http://dx.doi.org/10.1016/s0014-5793(02)03279-9DOI Listing
September 2002