Publications by authors named "Joanna I Loizou"

29Publications

Interplay between Cellular Metabolism and the DNA Damage Response in Cancer.

Cancers (Basel) 2020 Jul 25;12(8). Epub 2020 Jul 25.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria.

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http://dx.doi.org/10.3390/cancers12082051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463900PMC
July 2020

Genome-scale CRISPR screens are efficient in non-homologous end-joining deficient cells.

Sci Rep 2019 10 31;9(1):15751. Epub 2019 Oct 31.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, AKH BT 25.3, 1090, Vienna, Austria.

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http://dx.doi.org/10.1038/s41598-019-52078-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823505PMC
October 2019

Synthetic Lethal Interactions for Kinase Deficiencies to DNA Damage Chemotherapeutics.

Cancer Res 2019 Nov 6;79(22):5693-5698. Epub 2019 Aug 6.

CeMM Research Centre for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.

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http://dx.doi.org/10.1158/0008-5472.CAN-19-1364DOI Listing
November 2019

Mapping the Human Kinome in Response to DNA Damage.

Cell Rep 2019 01;26(3):555-563.e6

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, AKH BT 25.3, 1090 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.12.087DOI Listing
January 2019

Validating the concept of mutational signatures with isogenic cell models.

Nat Commun 2018 05 1;9(1):1744. Epub 2018 May 1.

Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, CB10 1SA, UK.

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http://dx.doi.org/10.1038/s41467-018-04052-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931590PMC
May 2018

Repair of UV-Induced DNA Damage Independent of Nucleotide Excision Repair Is Masked by MUTYH.

Mol Cell 2017 Nov;68(4):797-807.e7

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, AKH BT 25.3, 1090 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.10.021DOI Listing
November 2017

Perturbed hematopoiesis in mice lacking ATMIN.

Blood 2016 10 31;128(16):2017-2021. Epub 2016 Aug 31.

Mammalian Genetics Laboratory, The Francis Crick Institute, Lincoln's Inn Fields Laboratory, London, United Kingdom.

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http://dx.doi.org/10.1182/blood-2015-09-672980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147016PMC
October 2016

Programmed DNA breaks in lymphoid cells: repair mechanisms and consequences in human disease.

Immunology 2016 Jan 18;147(1):11-20. Epub 2015 Nov 18.

CeMM Research Centre for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.

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http://dx.doi.org/10.1111/imm.12547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988471PMC
January 2016

DNA replication stress: causes, resolution and disease.

Exp Cell Res 2014 Nov 30;329(1):85-93. Epub 2014 Sep 30.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, AKH BT 25.3, 1090 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2014.09.030DOI Listing
November 2014

ATMIN is required for the ATM-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress.

DNA Repair (Amst) 2014 Dec 26;24:122-130. Epub 2014 Sep 26.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, AKH BT 25.3 1090 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.dnarep.2014.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251980PMC
December 2014

Competition between NBS1 and ATMIN controls ATM signaling pathway choice.

Cell Rep 2012 Dec 6;2(6):1498-504. Epub 2012 Dec 6.

Mammalian Genetics Laboratory, Cancer Research UK, London Research Institute, London, UK.

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http://dx.doi.org/10.1016/j.celrep.2012.11.002DOI Listing
December 2012

Histone acetyltransferase cofactor Trrap is essential for maintaining the hematopoietic stem/progenitor cell pool.

J Immunol 2009 Nov 30;183(10):6422-31. Epub 2009 Oct 30.

International Agency for Research on Cancer (IARC), Lyon, France.

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http://dx.doi.org/10.4049/jimmunol.0901969DOI Listing
November 2009

Epigenetic information in chromatin: the code of entry for DNA repair.

Cell Cycle 2006 Apr 1;5(7):696-701. Epub 2006 Apr 1.

International Agency for Research on Cancer, Lyon, France.

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http://dx.doi.org/10.4161/cc.5.7.2616DOI Listing
April 2006

Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks.

Nat Cell Biol 2006 Jan 11;8(1):91-9. Epub 2005 Dec 11.

International Agency for Research on Cancer (IARC), 150 Cours Albert Thomas, 69008 Lyon, France.

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http://dx.doi.org/10.1038/ncb1343DOI Listing
January 2006

The protein kinase CK2 facilitates repair of chromosomal DNA single-strand breaks.

Cell 2004 Apr;117(1):17-28

Genome Damage and Stability Centre, University of Sussex, Science Park Road, Falmer, Brighton BN1 9RQ, United Kingdom.

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http://dx.doi.org/10.1016/s0092-8674(04)00206-5DOI Listing
April 2004

Interference of papillomavirus E6 protein with single-strand break repair by interaction with XRCC1.

EMBO J 2002 Sep;21(17):4741-8

Sektion Experimentelle Virologie, Universitätsklinikum Tuebingen, Elfriede-Aulhorn Strasse 6, D-72076 Tuebingen, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC126183PMC
http://dx.doi.org/10.1093/emboj/cdf443DOI Listing
September 2002