Publications by authors named "Joan Montaner"

100Publications

Blood biomarkers for the diagnosis and differentiation of stroke: A systematic review and meta-analysis.

Int J Stroke 2020 Aug 3:1747493020946157. Epub 2020 Aug 3.

Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.1177/1747493020946157DOI Listing
August 2020

Blood-based biomarkers and stem cell therapy in human stroke: a systematic review.

Mol Biol Rep 2020 Jul 7. Epub 2020 Jul 7.

Neurovascular Research Laboratory, Vall d'Hebron Institute of Research (VHIR), Universitat Autònoma de Barcelona, Pg. Vall d'Hebron, 119-129. Hospital Universitari Vall d'Hebron, 08035, Barcelona, Spain.

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http://dx.doi.org/10.1007/s11033-020-05627-9DOI Listing
July 2020

Natalizumab in acute ischemic stroke (ACTION II): a randomized, placebo-controlled trial.

Neurology 2020 Jun 26. Epub 2020 Jun 26.

Columbia University, New York, NY, USA (Dr. Elkind), Imperial College London, London, UK, and Alfried-Krupp Krankenhaus, Essen, Germany (Dr. Veltkamp); Vall d'Hebron Research Institute (VHIR), Barcelona, Spain, and Institute of Biomedicine of Seville (IBiS) Stroke Programme, Seville, Spain (Dr. Montaner); University of Texas, Austin, TX, USA (Dr. Johnston); Massachusetts General Hospital, Boston, MA, USA (Dr. Singhal); University of Washington, Seattle, WA, USA (Dr. Becker); Stanford University Medical Center, Stanford Stroke Center, Stanford, CA, USA (Dr. Lansberg); Biogen, Cambridge, MA, USA, at the time of the study (Dr. Tang and Dr. Kasliwal); Biogen, Cambridge, MA, USA (Dr. Elkins).

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http://dx.doi.org/10.1212/WNL.0000000000010038DOI Listing
June 2020

Break in the Stroke Chain of Survival due to COVID-19.

Stroke 2020 08 29;51(8):2307-2314. Epub 2020 May 29.

Neurovascular Research Laboratory, Vall d'Hebron Institute of Research (VHIR), Instituto de Biomedicina de Sevilla-IBiS, Barcelona, Spain (J.M., A.G.).

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http://dx.doi.org/10.1161/STROKEAHA.120.030106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282408PMC
August 2020

Prevalence and risk factors of silent brain infarcts in patients with AF detected by 3T-MRI.

J Neurol 2020 Sep 14;267(9):2675-2682. Epub 2020 May 14.

Neurovascular Research Group, Institute of Biomedicine of Seville, IBiS/Hospital Universitario Virgen del Rocío/CSIC, University of Seville, Av. Manuel Siurot s/n, 41013, Seville, Spain.

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http://dx.doi.org/10.1007/s00415-020-09887-0DOI Listing
September 2020

Multilevel omics for the discovery of biomarkers and therapeutic targets for stroke.

Nat Rev Neurol 2020 May 22;16(5):247-264. Epub 2020 Apr 22.

Neurovascular Research Laboratory, Vall d'Hebron Institute of Research, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1038/s41582-020-0350-6DOI Listing
May 2020

Identification of 20 novel loci associated with ischaemic stroke. Epigenome-wide association study.

Epigenetics 2020 Apr 6:1-10. Epub 2020 Apr 6.

Neurovascular Research Group, Department of Neurology of Hospital del Mar-IMIM (Institut Hospital del Mar d'Investigacions Mèdiques), Universitat Autònoma de Barcelona/DCEXS-Universitat Pompeu Fabra, Barcelona, Spain.

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http://dx.doi.org/10.1080/15592294.2020.1746507DOI Listing
April 2020

Inflammatory and stress markers predicting pneumonia, outcome, and etiology in patients with stroke: Biomarkers for predicting pneumonia, functional outcome, and death after stroke.

Neurol Neuroimmunol Neuroinflamm 2020 May 25;7(3). Epub 2020 Feb 25.

From the Charité - Universitätsmedizin Berlin (B.H., S.H., L.U., A.M.), Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Center for Stroke Research Berlin, NeuroCure Clinical Research Center and Department of Neurology, Berlin; Friedrich Loeffler Institute of Medical Microbiology (L.U.), University Medicine Greifswald, Greifswald, Germany; Neurovascular Research Laboratory (J.M., A.B.), Vall d'Hebron Institut de Recerca, Barcelona; Stroke Research Program (J.M.), Institute of Biomedicine of Seville, IBiS/Hospital Universitario Virgen del Rocío/CSIC/University of Seville; Department of Neurology (J.M.), Hospital Universitario Virgen Macarena, Spain; and Department of Medical Immunology (C.M.), Charité University Medicine and Labor Berlin - Charité Vivantes GmbH, Berlin, Germany.

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http://dx.doi.org/10.1212/NXI.0000000000000692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051196PMC
May 2020

Nighttime hypoxia affects global cognition, memory, and executive function in community-dwelling individuals with hypertension.

J Clin Sleep Med 2020 Feb 13;16(2):243-250. Epub 2020 Jan 13.

Neurovascular Research Laboratory, Institut de Recerca Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.5664/jcsm.8174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053040PMC
February 2020

Circulating Aquaporin-4 as A biomarker of early neurological improvement in stroke patients: A pilot study.

Neurosci Lett 2020 01 28;714:134580. Epub 2019 Oct 28.

Neurovascular Research Laboratory, Vall d'Hebron Institute of Research (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain; Stroke Research Program, Institute of Biomedicine of Seville, IBiS/Hospital Universitario Virgen del Rocío/CSIC/University of Seville & Department of Neurology, Hospital Universitario Virgen Macarena, Seville, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neulet.2019.134580DOI Listing
January 2020

Cardioembolic Ischemic Stroke Gene Expression Fingerprint in Blood: a Systematic Review and Verification Analysis.

Transl Stroke Res 2020 Jun 2;11(3):326-336. Epub 2019 Sep 2.

Neurovascular Research Laboratory, Vall d'Hebron Institute of Research (VHIR), Hospital Vall d'Hebron, Universitat Autònoma de Barcelona, Pg. Vall d'Hebron 119-129, 08035, Barcelona, Spain.

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http://dx.doi.org/10.1007/s12975-019-00730-xDOI Listing
June 2020

Application of an Aptamer-Based Proteomics Assay (SOMAscan™) in Rat Cerebrospinal Fluid.

Methods Mol Biol 2019 ;2044:221-231

Neurovascular Research Laboratory, Vall d'Hebron Institute of Research (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1007/978-1-4939-9706-0_13DOI Listing
June 2020

Validation of a clinical-genetics score to predict hemorrhagic transformations after rtPA.

Neurology 2019 08 31;93(9):e851-e863. Epub 2019 Jul 31.

From the Neurovascular Research Laboratory (C.C., A.B.), Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona; Stroke Pharmacogenomics and Genetics (N.C., N.-T.A.) and Stroke Genomics and Genetics (E.M.), Fundació Docència i Recerca Mútua Terrassa; Department of Neuroscience (A.D.), Hospital Germans Trias i Pujol; Stroke Unit (E.L.-C.), Hospital Universitario Central de Asturias; Stroke Unit (M.R., C.A.M.), Hospital Universitari Vall d'Hebron; Stroke Unit, Hospital Universitari Vall d'Hebron; Department of Neurology (E.G.-S., C.S.-T., M.M.-C., J.J.-C., J.R.), Neurovascular Research Group, IMIM-Hospital del Mar; Neurobiology Laboratory (C.V.-B.), Institut d'Investigacio Sanitaria de Palma; Department of Neurology (R.D.N.), Hospital Universitari Son Espases; Department of Neurology (V.O.), Hospital Clínic i Provincial de Barcelona; Department of Neurology (J.F.A.), Hospital Clínico Universitario, University of Valladolid; Department of Neurology (T.S.) and Experimental Research Unit (G.S.-H.), Hospital Universitario de Albacete; Department of Neurology (J.M.-F.), Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau; Department of Neurology (M.F.), Hospital de Basurto; Department of Neurology (J.A.C.), Virgen del Rocío & Macarena Hospitals, IBIS, Spain; Department of Clinical Neuroscience/Neurology (T.T.), Sahlgrenska Academy at University of Gothenburg and Sahlgrenska University Hospital, Sweden; Division of Emergency Medicine (L.H.), Department of Psychiatry (L.I., C.C.), and Department of Neurology (J.-M.L.), Washington University School of Medicine, St. Louis, MO; Department of Neurology (D.S.), Helsinki University Hospital, Finland; Department of Neurology (J.M.), Virgen del Rocío & Macarena Hospitals, IBIS. Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona; and Stroke Pharmacogenomics and Genetics (I.F.-C.), Fundació Docència i Recerca Mútua Terrassa, Hospital Universitari Mútua de Terrassa, Stroke Pharmacogenomics and Genetics, IIB-Sant Pau, Spain.

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http://dx.doi.org/10.1212/WNL.0000000000007997DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745730PMC
August 2019

Comments on: "Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels as a Biomarker of Acute Intracerebral Hemorrhage".

J Stroke Cerebrovasc Dis 2019 09 28;28(9):2585-2586. Epub 2019 Jun 28.

Neurovascular Research Laboratory, Vall d'Hebron Institute of Research (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10523057193028
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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2019.06.014DOI Listing
September 2019

Matrix metalloproteinases and ADAMs in stroke.

Cell Mol Life Sci 2019 Aug 5;76(16):3117-3140. Epub 2019 Jun 5.

Neurovascular Research Laboratory, Vall d'Hebron Institute of Research, Universitat Autònoma de Barcelona, Passeig de la Vall d'Hebron, 119-129, 08035, Barcelona, Spain.

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http://dx.doi.org/10.1007/s00018-019-03175-5DOI Listing
August 2019

Antibiotic Class and Outcome in Post-stroke Infections: An Individual Participant Data Pooled Analysis of VISTA-Acute.

Front Neurol 2019 14;10:504. Epub 2019 May 14.

Department of Neurology, NeuroCure Clinical Research Center, Center for Stroke Research Berlin, Charité Universitaetsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.3389/fneur.2019.00504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527959PMC
May 2019

Neuroprotective Effects of Diets Containing Olive Oil and DHA/EPA in a Mouse Model of Cerebral Ischemia.

Nutrients 2019 May 18;11(5). Epub 2019 May 18.

Neurovascular Research Group, Institute of Biomedicine of Seville, IBiS, Hospital Universitario Virgen del Rocío, Av. Manuel Siurot s/n, 41013 Seville; Spain.

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http://dx.doi.org/10.3390/nu11051109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566717PMC
May 2019

Peripheral administration of human recombinant ApoJ/clusterin modulates brain beta-amyloid levels in APP23 mice.

Alzheimers Res Ther 2019 05 10;11(1):42. Epub 2019 May 10.

Neurovascular Research Laboratory, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, 08035, Barcelona, Spain.

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http://dx.doi.org/10.1186/s13195-019-0498-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511153PMC
May 2019

Venous and arterial TNF-R1 predicts outcome and complications in acute subarachnoid hemorrhage.

Neurocrit Care 2019 08;31(1):107-115

Neurovascular Research Laboratory, Vall d'Hebron Institute of Research (VHIR), Barcelona, Spain.

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http://link.springer.com/10.1007/s12028-019-00669-9
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http://dx.doi.org/10.1007/s12028-019-00669-9DOI Listing
August 2019

Diagnostic accuracy of noncontrast CT imaging markers in cerebral venous thrombosis.

Neurology 2019 02 18;92(8):e841-e851. Epub 2019 Jan 18.

From the Departments of Radiology (P.-J.B., P.D.) and Neurology (R.L.), University Hospitals Leuven, Belgium; Department of Neurology (S.M.Z., J.M.C.), Amsterdam University Medical Centers, Amsterdam, the Netherlands; Department of Neurology (C.-G.E.), John Hunter Hospital, University of Newcastle, Australia; Stroke Department (M.A.B., A.A.), Instituto Nacional de Neurología y Neurocirugía Dr. Manuel Velasco Suárez, México City, México; Department of Head and Neck (P.C.), Neurology Unit, Fondazione Poliambulanza, Brescia, Italy; Departments of Head and Neck (P.C.) and Clinical and Experimental Sciences (A.P.), Neurology Clinic, University of Brescia, Italy; Neurology Department (I.E., J.M.), University Hospitals Virgen del Rocio and Macarena, Seville; Neurovascular Lab (I.E., J.M.), Instituto de Biomedicina de Sevilla, Spain; Department of Neurology (D.R.), Nîmes University Hospital, France; Department of Neurosciences (R.L.), Experimental Neurology and Leuven Institute for Neuroscience and Disease (LIND), KU Leuven-University of Leuven; Laboratory of Neurobiology (R.L.), Center for Brain & Disease Research, VIB, Leuven, Belgium; Departments of Radiology (N.H.) and Neurology (F.F., T.G.), Medical University of Graz, Austria; Department of Neurology (J.J.C., E.G.-S.), Neurovascular Research Group, IMIM-Hospital del Mar, Barcelona; Universitat Autònoma de Barcelona (J.J.C., E.G.-S.), Spain; Department of Neurology (S.H., J.P., T.T.), Helsinki University Hospital, Finland; Department of Neurology (J.M.), Hospital Universitario Virgen Macarena, Seville, Spain; Department of Neurology (C.W.), University Hospital Essen, Germany; The Florey Institute of Neuroscience and Mental Health (L.C.), University of Melbourne; Australia School of Medicine (H.A.), Faculty of Health, Deakin University; Interventional Neuroradiology Service (H.A.), Radiology Department, Austin Health, Melbourne; Interventional Neuroradiology Service (H.A.), Radiology Department, Monash Health, Melbourne, Australia; Department of Clinical Neuroscience/Neurology (T.T.), Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg; Department of Neurology (T.T.), Sahlgrenska University Hospital, Gothenburg, Sweden; Stroke Division, Florey Institute of Neuroscience and Mental Health (V.T.), University of Melbourne, Heidelberg; and Department of Neurology (V.T.), Austin Health, Heidelberg, Australia.

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http://dx.doi.org/10.1212/WNL.0000000000006959DOI Listing
February 2019

Cognitive Impact of Cerebral Small Vessel Disease Changes in Patients With Hypertension.

Hypertension 2019 02;73(2):342-349

From the Neurovascular Research Lab, Vall Hebron Research Institute (J.J.-B., I.R.-L., O.A., E.G., A.P., E.O., O.M., J.M., M.N., O.V., J.P., P.D.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.118.12090DOI Listing
February 2019

PATJ Low Frequency Variants Are Associated With Worse Ischemic Stroke Functional Outcome.

Circ Res 2019 01;124(1):114-120

From the Department of Neurology, Neurovascular Research Group, Hospital del Mar Medical Research Institute, Universitat Autònoma de Barcelona/DCEXS-Universitat Pompeu Fabra (M.M.-C., C.S.-T., E.G.-S., A.R.-C., A.O., E.C.-G., R.M.V.-H., J.R., J.J.-C.).

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.118.31353
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http://dx.doi.org/10.1161/CIRCRESAHA.118.313533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501820PMC
January 2019

Safety of Early Carotid Artery Stenting for Symptomatic Stenosis in Daily Practice.

Eur J Vasc Endovasc Surg 2018 12 31;56(6):776-782. Epub 2018 Aug 31.

Interventional Neuroradiology, Department of Radiology, Hospital Universitario Virgen del Rocío, Sevilla, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.ejvs.2018.07.026DOI Listing
December 2018

Absolute risk and predictors of the growth of acute spontaneous intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data.

Lancet Neurol 2018 10 14;17(10):885-894. Epub 2018 Aug 14.

Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S14744422183025
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http://dx.doi.org/10.1016/S1474-4422(18)30253-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143589PMC
October 2018

Inflammatory molecules might become both biomarkers and therapeutic targets for stroke management.

Ther Adv Neurol Disord 2018 6;11:1756286418789340. Epub 2018 Aug 6.

Neurovascular Research Laboratory, Vall d'Hebron Institute of Research, Pg. Vall d'Hebron 119-129, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.

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http://dx.doi.org/10.1177/1756286418789340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080077PMC
August 2018

Microbiological Etiologies of Pneumonia Complicating Stroke: A Systematic Review.

Stroke 2018 07 18;49(7):1602-1609. Epub 2018 Jun 18.

From the Greater Manchester Comprehensive Stroke Centre, Manchester Academic Health Science Centre, Salford Royal Foundation Trust, United Kingdom (A.K.K., C.J.S.).

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http://dx.doi.org/10.1161/STROKEAHA.117.020250DOI Listing
July 2018

Detection of plasma MMP-9 within minutes. Unveiling some of the clues to develop fast and simple electrochemical magneto-immunosensors.

Biosens Bioelectron 2018 Sep 11;115:45-52. Epub 2018 May 11.

Diagnostic Nanotools Group, Cibbim-Nanomedicine, Vall Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain; CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bios.2018.05.020DOI Listing
September 2018

Characterization of the rat cerebrospinal fluid proteome following acute cerebral ischemia using an aptamer-based proteomic technology.

Sci Rep 2018 05 21;8(1):7899. Epub 2018 May 21.

Neurovascular Research Laboratory, Vall d'Hebron Institute of Research (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1038/s41598-018-26237-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962600PMC
May 2018

Protective Effects of Endothelial Progenitor Cell-Derived Extracellular Mitochondria in Brain Endothelium.

Stem Cells 2018 09 15;36(9):1404-1410. Epub 2018 Jul 15.

Neuroprotection Research Laboratory, Departments of Radiology and Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, USA.

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http://dx.doi.org/10.1002/stem.2856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407639PMC
September 2018

Arterial Stiffness Is Associated With Basal Ganglia Enlarged Perivascular Spaces and Cerebral Small Vessel Disease Load.

Stroke 2018 05 18;49(5):1279-1281. Epub 2018 Apr 18.

From the Neurovascular Laboratory, Vall Hebron's Research Institute, Barcelona, Spain (I.R.-L., J.J.-B., X.C., A.L.-R., J.M., P.D.).

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http://dx.doi.org/10.1161/STROKEAHA.118.020163DOI Listing
May 2018

Endothelial Progenitor Cell Secretome and Oligovascular Repair in a Mouse Model of Prolonged Cerebral Hypoperfusion.

Stroke 2018 04 6;49(4):1003-1010. Epub 2018 Mar 6.

From the Neuroprotection Research Laboratory, Departments of Radiology and Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown (T.M., K.H., H.T., A.C.L., K.W., J.L., E.H.L., K.A.); and Neurovascular Research Laboratory, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Spain (A.M., P.M.-S.S., M.G.-S., E.M.-G., J.M., A.R.).

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http://dx.doi.org/10.1161/STROKEAHA.117.019346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871569PMC
April 2018

Usefulness of ADAMTS13 to predict response to recanalization therapies in acute ischemic stroke.

Neurology 2018 03 14;90(12):e995-e1004. Epub 2018 Feb 14.

From the Neurovascular Research Laboratory (A.B., T.G.-B., A.P., C.B., A.S., J.M.), Institut de Recerca, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Spain; Clinical Proteomics Research Center and Cardio-Neurology Clinic (M.N., E.L.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; and Stroke Unit (J.P., M.R., C.M.), Hospital Universitari Vall d'Hebron, Barcelona, Spain.

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http://dx.doi.org/10.1212/WNL.0000000000005162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874450PMC
March 2018

Using magnetic beads and signal amplifiers to produce short and simple immunoassays: Application to MMP-9 detection in plasma samples.

Anal Chim Acta 2018 Jan 10;999:144-154. Epub 2017 Nov 10.

Diagnostic Nanotools Group, Cibbim-Nanomedicine, Vall Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain; CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Spain. Electronic address:

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http://dx.doi.org/10.1016/j.aca.2017.11.013DOI Listing
January 2018

Selection bias in clinical stroke trials depending on ability to consent.

BMC Neurol 2017 Dec 4;17(1):206. Epub 2017 Dec 4.

Center for Stroke Research Berlin, Charité University Hospital Berlin, Charitéplatz 1, 10115, Berlin, Germany.

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http://dx.doi.org/10.1186/s12883-017-0989-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716230PMC
December 2017

Simvastatin blocks soluble SSAO/VAP-1 release in experimental models of cerebral ischemia: Possible benefits for stroke-induced inflammation control.

Biochim Biophys Acta Mol Basis Dis 2018 Feb 22;1864(2):542-553. Epub 2017 Nov 22.

Biochemistry and Molecular Biology Department, Institute of Neurosciences, Universitat Autònoma de Barcelona, Bellaterra, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2017.11.014DOI Listing
February 2018

is associated with lacunar ischemic stroke and deep ICH: Meta-analyses among 21,500 cases and 40,600 controls.

Neurology 2017 Oct 27;89(17):1829-1839. Epub 2017 Sep 27.

From the Centre for Clinical Brain Sciences (K.R., C.L.M.S.), College of Medicine and Veterinary Medicine (V.S., H.M.), and Institute for Genetics and Molecular Medicine (C.L.M.S.), University of Edinburgh, UK; Institute for Stroke and Dementia Research (R.M., M.D.), Klinikum der Universität München, Munich, Germany; Center for Human Genetic Research (C.D.A., F.R., J.R.) and J. Philip Kistler Stroke Research Center (C.D.A., F.R., N.S.R., J.R.) and Division of Neurocritical Care and Emergency Neurology (C.D.A., F.R., J.R.), Department of Neurology, Massachusetts General Hospital, Boston; Program in Medical and Population Genetics (C.D.A., F.R., J.R.), Broad Institute, Cambridge, MA; Population Health Research Institute (M.C., M.O., G.P.), McMaster University, Hamilton Health Sciences Centre, Ontario, Canada; Department of Medicine (T.D., B.D.M.), University of Maryland School of Medicine, Baltimore; Division of Neurocritical Care and Emergency Neurology (G.J.F.), Department of Neurology, Yale University School of Medicine, New Haven, CT; Stroke Pharmacogenomics and Genetics (I.F.-C.), Fundació Docència i Recerca Mutua Terrassa, Mutua de Terrassa Hospital; Neurovascular Research Unit (J.J.-C.), Department of Neurology, and Program in Inflammation and Cardiovascular Disorders (J.J.-C.), Institut Municipal d'Investigacio´Medica-Hospital del Mar, Universitat Autonoma de Barcelona, Spain; Department of Clinical Sciences Lund (A.L.), Neurology, Lund University; Department of Neurology and Rehabilitation Medicine (A.L., M.S.), Neurology, Skåne University Hospital, Lund, Sweden; Neurovascular Research Laboratory and Neurovascular Unit (J.M.), Institut de Recerca, Hospital Vall d'Hebron, Universitat Autonoma de Barcelona, Spain; HRB Clinical Research Facility (M.O.), NUI Galway, and University Hospital Galway, Ireland; Department of Neurology (A.S.), Jagiellonian University Medical College, Krakow, Poland; Cardiovascular Epidemiology Research Group (M.S.), Department of Clinical Sciences, Lund University, Malmö, Sweden; Department of Clinical Neurosciences (M.T., H.S.M.), University of Cambridge, UK; Department of Neurology (S.L.P.), Brain Centre Rudolf Magnus, University Medical Center Utrecht, the Netherlands; Boston University Schools of Medicine and Public Health (S.S.); Framingham Heart Study (S.S.), Framingham, MA; Departments of Neurology and Public Health Sciences (B.B.W.), University of Virginia, Charlottesville; Department of Neurology (D.W.), University of Cincinnati College of Medicine, OH; Geriatrics Research and Education Clinical Center (B.D.M.), Baltimore Veterans Administration Medical Center, MD; and Munich Cluster for Systems Neurology (SyNergy) (M.D.), Germany.

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http://dx.doi.org/10.1212/WNL.0000000000004560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664302PMC
October 2017

Intravenous treatment with human recombinant ApoA-I Milano reduces beta amyloid cerebral deposition in the APP23-transgenic mouse model of Alzheimer's disease.

Neurobiol Aging 2017 12 5;60:116-128. Epub 2017 Sep 5.

Neurovascular Research Laboratory, Vall d'Hebron Research Insitute, Universitat Autònoma de Barcelona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.08.028DOI Listing
December 2017

Circulating cell-free DNA is a predictor of short-term neurological outcome in stroke patients treated with intravenous thrombolysis.

J Circ Biomark 2016 Jan-Dec;5:1849454416668791. Epub 2016 Sep 26.

Neurovascular Research Laboratory, Institut de Recerca, Hospital Universitari Vall d'Hebron. Universitat Autonoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1177/1849454416668791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548318PMC
September 2016

Systematic Review of Cysteine-Sparing NOTCH3 Missense Mutations in Patients with Clinical Suspicion of CADASIL.

Int J Mol Sci 2017 Sep 13;18(9). Epub 2017 Sep 13.

Stroke Pharmacogenomics and Genetics, Fundació Docència i Recerca Mútua Terrassa, Hospital Mútua de Terrassa, 08221 Terrassa, Spain.

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http://dx.doi.org/10.3390/ijms18091964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618613PMC
September 2017

Sepsis biomarkers reprofiling to predict stroke-associated infections.

J Neuroimmunol 2017 11 26;312:19-23. Epub 2017 Aug 26.

Neurovascular Research Laboratory, Vall d'Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jneuroim.2017.08.012DOI Listing
November 2017

The choroid plexus is a key cerebral invasion route for T cells after stroke.

Acta Neuropathol 2017 12 31;134(6):851-868. Epub 2017 Jul 31.

Institute for Stroke and Dementia Research, Klinikum der Universität München, Feodor-Lynen-Str. 17, 81377, Munich, Germany.

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http://dx.doi.org/10.1007/s00401-017-1758-yDOI Listing
December 2017

Brain hemorrhage recurrence, small vessel disease type, and cerebral microbleeds: A meta-analysis.

Neurology 2017 Aug 26;89(8):820-829. Epub 2017 Jul 26.

From the Stroke Research Centre (A.C., Y.Y., S.M.G., H.R.J., D.J.W.), Department of Brain Repair and Rehabilitation, UCL Institute of Neurology and The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK; Hemorrhagic Stroke Research Program, Department of Neurology (A.C., A.B., E.E.S., A.V., S.M.G.), Massachusetts General Hospital Stroke Research Center, Harvard Medical School, Boston; Department of Neurosurgery (T.I.), Kushiro City General Hospital, Hokkaido, Japan; Degenerative & Vascular Cognitive Disorders (S.M., B.C., C.C.), Univ Lille, Inserm, CHU Lille, France; Centre for Clinical Brain Sciences (N.S., R.A.-S.S.), University of Edinburgh, UK; Department of Neurology (A.P.), Cliniques Universitaires UCL Saint Luc; Department of Neurology (Y.V., P.L.), CHU Dinant Godinne, Université Catholique de Louvain; Institute of Neuroscience (Y.V., P.L.), Université Catholique de Louvain, Brussels, Belgium; Department of Clinical Neurosciences (J.-C.B.), University of Cambridge, Addenbrooke's Hospital, UK; UMR 894 INSERM-Université Paris 5 (J.-C.B.), Sorbonne Paris Cité, Paris, France; Department of Neurology (M.H.-G., J.M.), Hospital Vall d'Hebron, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Spain; Department of Neurology (D.-W.K., J.S.K.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology (H.N.), Hiroshima Prefectural Hospital, Japan; and Hotchkiss Brain Institute (E.E.S.), University of Calgary, Canada.

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http://dx.doi.org/10.1212/WNL.0000000000004259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580863PMC
August 2017

Quinolinyl Nitrone RP19 Induces Neuroprotection after Transient Brain Ischemia.

ACS Chem Neurosci 2017 10 9;8(10):2202-2213. Epub 2017 Aug 9.

Department of Investigation, Hospital Ramón y Cajal, IRYCIS , Madrid 28034, Spain.

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http://pubs.acs.org/doi/10.1021/acschemneuro.7b00126
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http://dx.doi.org/10.1021/acschemneuro.7b00126DOI Listing
October 2017

Blood Biomarkers for the Early Diagnosis of Stroke: The Stroke-Chip Study.

Stroke 2017 09 17;48(9):2419-2425. Epub 2017 Jul 17.

From the Neurovascular Research Laboratory, Vall d'Hebron Institut de Recerca (VHIR), Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Spain (A.B., A.P., D.G., T.G.-B., J.M.); Stroke Unit, Hospital Universitari Germans Trias i Pujol, Barcelona, Spain (E.L.-C., M.H.-P., M.M., A.D.); Gendiag.exe, S.L., Barcelona, Spain (S.P., C.F.-C., E.S.); Cellular and Molecular Neurobiology Research Group, Fundació Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Barcelona, Spain (T.G.); Stroke Unit, Hospital Universitari Vall d'Hebron, Barcelona, Spain (M.R., J.M.); Stroke Unit, Hospital Universitari de Bellvitge, Barcelona, Spain (P.C., L.C., H.Q., F.R.); Stroke Unit, Hospital Universitari Josep Trueta, Girona, Spain (M.T., Y.S., J.S.); Complejo Hospitalario Universitario A Coruña, Spain (M.C.); Stroke Unit, Hospital Universitari Verge de la Cinta de Tortosa, Spain (M.G., S.R., J.J.B.); and Stroke Unit, Hospital Universitari Joan XXIII, Tarragona, Spain (X.U., R.M.).

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http://dx.doi.org/10.1161/STROKEAHA.117.017076DOI Listing
September 2017

Obstructive sleep apnea and silent cerebral infarction in hypertensive individuals.

J Sleep Res 2018 04 20;27(2):232-239. Epub 2017 Jun 20.

CIBER Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.

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http://dx.doi.org/10.1111/jsr.12571DOI Listing
April 2018

GRECOS Project (Genotyping Recurrence Risk of Stroke): The Use of Genetics to Predict the Vascular Recurrence After Stroke.

Stroke 2017 05 14;48(5):1147-1153. Epub 2017 Apr 14.

From the Stroke Pharmacogenomics and Genetics, Fundacio Docència i Recerca MutuaTerrassa, Spain (I.F.-C., E.G., C.G.-F., N.C., E.M.); Neurovascular Research Laboratory and Neurovascular Unit, Neurology and Medicine Departments-Universitat Autònoma de Barcelona (I.F.-C., M.M., D.G., C.N., C.C., S.D.-M., P.D., J.M.) and Neurology Department (M.Ribó, M.Rubiera, J.A.-S., C.A.M.), Vall d'Hebron Hospital, Barcelona, Spain; Neuroepigenetics Research Group, Navarrabiomed, Pamplona, Spain (M.M.); Department of Neurology, Hospital Universitari Dr Josep Trueta, Institut d'Investigació Biomèdica de Girona, Spain (M.C., J.S.); Department of Neurology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain (S.M., J.M.-F.); Department of Neurology, Hospital de Basurto, Bilbao, Spain (M.F.); Department of Neurology, Hospital del Mar and Centre de Regulació Genòmica, Universitat Pompeu Fabra, Barcelona, Spain (J.J.-C., J.R.); Department of Neurology, Hospital de Bellvitge, Hospitalet del Llobregat, Spain (M.A.F., F.R.); Department of Neurology, Hospital Universitari Sagrat Cor, Barcelona, Spain (M.G.O., A.A.); Department of Neurology, Hospital de Mataró, Spain (E.P.); Department of Neurology, Hospital Universitari Germans Trias i Pujol, Badalona, Spain (N.P.d.l.O., A.D.); Department of Neurology, Hospital Donostia, San Sebastián, Spain (M.M.-Z.); Department of Neurology, Hospital Ramón y Cajal, Madrid, Spain (J.M.); Department of Neurology, Hospital Universitario Virgen del Rocío, Sevilla, Spain (F.M.); Department of Neurology, Corporació Sanitària Parc Taulí, Sabadell, Spain (D.C.); Department of Neurology, Hospital Universitario Virgen de las Nieves, Granada, Spain (C.P.); Department of Neurology, Hospital Universitario Arnau De Vilanova, Lleida, Spain (F.P.); Department of Neurology, Hospital de Granollers, Spain (D.C.); Department of Neurology, Hospital Mútua de Terrassa, Spain (I.N., J.K.); Department of Neurology, Hospital Clinico Universitario Lozano Blesa, Zaragoza, Spain (C.T.); Department of Neurology, Hospital De Navarra, Pamplona, Spain (N.A.); Department of Neurology, Hospital Clínico Universitario de Valladolid, Spain (J.F.A.); Department of Biology, Center for Health Disparities, East Carolina University, Greenville, North Carolina (K.K.); Department of Public Health Sciences, Center for Public Health Genomics (W.-M.C.); Departments of Neurology (B.W.), Public Health Sciences (B.W., M.S.), and Biochemistry and Molecular Genetics (M.S.), and Center for Public Health Genomics (M.S.), University of Virginia, Charlottesville.

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.116.014322
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http://dx.doi.org/10.1161/STROKEAHA.116.014322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473776PMC
May 2017

New thrombolytic strategy providing neuroprotection in experimental ischemic stroke: MMP10 alone or in combination with tissue-type plasminogen activator.

Cardiovasc Res 2017 Aug;113(10):1219-1229

Laboratory of Atherothrombosis, Program of Cardiovascular Diseases, CIMA-University of Navarra, IdiSNA, CIMA Building, Av. Pio XII, 55, 31008 Pamplona, Navarra, Spain.

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http://dx.doi.org/10.1093/cvr/cvx069DOI Listing
August 2017

The impact of post-stroke complications on in-hospital mortality depends on stroke severity.

Eur Stroke J 2017 Mar 28;2(1):54-63. Epub 2016 Nov 28.

Neurovascular Research Laboratory, Institut de Recerca, Hospital Universitari Vall d'Hebron-Universitat Autónoma de Barcelona, Spain.

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http://dx.doi.org/10.1177/2396987316681872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453178PMC
March 2017

C-reactive protein in the detection of post-stroke infections: systematic review and individual participant data analysis.

J Neurochem 2017 04 8;141(2):305-314. Epub 2017 Mar 8.

Neurovascular Research Laboratory, Institut de Recerca, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1111/jnc.13973DOI Listing
April 2017

Neuroprotective diets for stroke.

Neurochem Int 2017 Jul 2;107:4-10. Epub 2017 Feb 2.

Neurovascular Research Group, Institute de Biomedicine of Seville, IBiS/Hospital Universitario Virgen del Rocío/CSIC/University of Seville, Av. Manuel Siurot s/n, 41013, Seville, Spain; Department of Neurology, Hospital Universitario Virgen Macarena, Avenida Doctor Fedriani, no. 3, 41007, Seville, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neuint.2017.01.013DOI Listing
July 2017

Blood markers of inflammation and endothelial dysfunction in cardioembolic stroke: systematic review and meta-analysis.

Biomarkers 2017 May - Jun;22(3-4):200-209. Epub 2017 Feb 14.

b Neurovascular Research Laboratory , Vall d'Hebron University Hospital Research Institute (VHIR), Universitat Autònoma de Barcelona , Barcelona , Spain.

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http://dx.doi.org/10.1080/1354750X.2017.1286689DOI Listing
April 2017

N-terminal pro-brain natriuretic peptide and subclinical brain small vessel disease.

Neurology 2016 Dec 9;87(24):2533-2539. Epub 2016 Nov 9.

From the Neurovascular Research Laboratory (A.V.-B., I.R.-L., A.P., J.J.-B., J.M., P.D.), Vall d'Hebron Research Institute, Department of Medicine, Universitat Autònoma de Barcelona; Stroke Unit (J.M.), Neurology Department, Vall d'Hebron Hospital; and Clinical Biochemistry Unit (L.M.C.), Hospital Universitari Vall d'Hebron, Barcelona, Spain.

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http://dx.doi.org/10.1212/WNL.0000000000003423DOI Listing
December 2016

Principles of precision medicine in stroke.

J Neurol Neurosurg Psychiatry 2017 Jan 19;88(1):54-61. Epub 2016 Oct 19.

Department of Neurology, Neurovascular Imaging Research Core and the UCLA Stroke Center, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.

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http://dx.doi.org/10.1136/jnnp-2016-314587DOI Listing
January 2017

Profiling and identification of new proteins involved in brain ischemia using MALDI-imaging-mass-spectrometry.

J Proteomics 2017 01 22;152:243-253. Epub 2016 Nov 22.

Universitat Autònoma de Barcelona, Neurovascular Research Laboratory, Institut de Recerca Vall d'Hebron, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2016.11.014DOI Listing
January 2017

Galectin-3 is not an outcome biomarker in ischemic stroke. Letter concerning the study 'Role of galectin-3 in plasma as a predictive biomarker of outcome after acute intracerebral hemorrhage.

J Neurol Sci 2016 12 17;371:67-68. Epub 2016 Oct 17.

Neurovascular Research Laboratory, Institut de Recerca, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2016.10.023DOI Listing
December 2016