Joan Merrill

Joan Merrill

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Development and content validity of the Lupus Foundation of America rapid evaluation of activity in lupus (LFA-REAL™): a patient-reported outcome measure for lupus disease activity.

Health Qual Life Outcomes 2019 Jun 7;17(1):99. Epub 2019 Jun 7.

Department of Clinical Pharmacology, Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, OK, 73104, USA.

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http://dx.doi.org/10.1186/s12955-019-1151-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555910PMC
June 2019

Immunologic findings precede rapid lupus flare after transient steroid therapy.

Sci Rep 2019 Jun 13;9(1):8590. Epub 2019 Jun 13.

Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, 73104, USA.

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http://dx.doi.org/10.1038/s41598-019-45135-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565690PMC
June 2019

Osteopontin and Disease Activity in Patients with Recent-onset Systemic Lupus Erythematosus: Results from the SLICC Inception Cohort.

J Rheumatol 2019 May 15;46(5):492-500. Epub 2019 Jan 15.

From the Rheumatology/Division of Neuro and Inflammation Sciences, Department of Clinical and Experimental Medicine, Linköping University, Linköping; Department of Medicine, Unit of Rheumatology, Karolinska Institutet and Karolinska University Hospital, Stockholm; Department of Clinical Sciences Lund, Section of Rheumatology, Lund University, Lund; Unit for Clinical Therapy Research (ClinTRID), Karolinska University, Stockholm, Sweden; Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital and University of Toronto, Toronto, Ontario; Division of Rheumatology, Centre Hospitalier Universitaire (CHU) de Québec - Université Laval, Quebec City, Quebec; Division of Rheumatology, Cumming School of Medicine - University of Calgary, Calgary, Alberta; Division of Rheumatology, Department of Medicine, McGill University Health Centre, Montreal, Quebec; Division of Rheumatology, Department of Medicine and Department of Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia; Department of Medicine and Community Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada; Instituto Nacional de Ciencias Médicas y Nutrición, Mexico City, Mexico; Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea; Rheumatology Research Group, School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham; Centre for Rheumatology Research, University College, London; Lupus Research Unit, The Rayne Institute, St. Thomas' Hospital, King's College London School of Medicine, London; Lanarkshire Centre for Rheumatology, Hairmyres Hospital, East Kilbride, Scotland; Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, The University of Manchester and UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Foundation Trust, Manchester, UK; Cedars-Sinai/David Geffen School of Medicine at University of California at Los Angeles, Los Angeles, California; Department of Clinical Pharmacology, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma; Department of Medicine, State University of New York (SUNY) Downstate Medical Center, Brooklyn, New York; Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, Alabama; Department of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Feinstein Institute for Medical Research, Manhasset, New York; Division of Rheumatology and Immunology, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina; Autoimmunity Institute, Allegheny Health Network, Pittsburgh, Pennsylvania; Northwestern University and Feinberg School of Medicine, Chicago, Illinois; Division of Rheumatology, Emory University School of Medicine, Atlanta, Georgia; University of California San Diego School of Medicine, La Jolla, California; Division of Rheumatology, Medical University of South Carolina, Charleston, South Carolina; Division of Rheumatology, Columbia University Medical Center, New York, New York, USA; Department of Rheumatology, Center for Rheumatology Research Fossvogur Landspitali University Hospital, Reyjkavik, Iceland; Autoimmune Disease Unit, Department of Internal Medicine, Hospital Universitario Cruces, BioCruces Health Research Institute, University of the Basque Country, Barakaldo; Josep Font Autoimmune Diseases Laboratory, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Department of Autoimmune Diseases, Hospital Clínic, Barcelona, Spain; Division of Rheumatology, Department of Internal Medicine, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey; Copenhagen Lupus and Vasculitis Clinic, Centre for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; Department of Rheumatology, Kantousspital, Schaffhausen, Switzerland.

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http://www.jrheum.org/lookup/doi/10.3899/jrheum.180713
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http://dx.doi.org/10.3899/jrheum.180713DOI Listing
May 2019

Measuring disease activity in SLE is an ongoing struggle.

Nat Rev Rheumatol 2019 Apr;15(4):194-195

Department of Clinical Pharmacology, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.

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http://dx.doi.org/10.1038/s41584-019-0190-1DOI Listing
April 2019

Construction of a Frailty Index as a Novel Health Measure in Systemic Lupus Erythematosus.

J Rheumatol 2019 Apr 15. Epub 2019 Apr 15.

From the Divisions of Rheumatology and Geriatric Medicine, Department of Medicine, Dalhousie University; Department of Community Health and Epidemiology, Dalhousie University, Halifax, Nova Scotia; Divisions of Rheumatology and Clinical Epidemiology, Department of Medicine, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire (CHU) de Québec et Université Laval, Quebec City, Quebec; Division of Rheumatology, Cumming School of Medicine, University of Calgary, Calgary, Alberta; Center for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital and University of Toronto, Toronto, Ontario; University of Manitoba, Winnipeg, Manitoba; Division of Rheumatology, Department of Medicine and Department of Pathology, Queen Elizabeth II Health Sciences Center and Dalhousie University, Halifax, Nova Scotia, Canada; Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea; Rheumatology Research Group, School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham; Arthritis Research UK Epidemiology Unit, Faculty of Biology Medicine and Health, Manchester Academic Health Sciences Center, The University of Manchester, and National Institute for Health Research (NIHR) Manchester Musculoskeletal Biomedical Research Centre, Manchester University National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Center, Manchester; Center for Rheumatology, Department of Medicine, University College London, London; Lanarkshire Center for Rheumatology, Hairmyres Hospital, East Kilbride, Scotland; Lupus Research Unit, The Rayne Institute, St Thomas' Hospital, King's College London School of Medicine, London, UK; Instituto Nacional de Ciencias Medicas y Nutrición, Mexico City, Mexico; Cedars-Sinai/David Geffen School of Medicine at University of California Los Angeles (UCLA), Los Angeles, California; Department of Clinical Pharmacology, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma; Department of Medicine, State University of New York (SUNY) Downstate Medical Center, Brooklyn, New York; Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama; Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, North Carolina; Northwestern University and Feinberg School of Medicine, Chicago, Illinois; Lupus Center of Excellence, Allegheny Health Network, Pittsburgh, Pennsylvania; Feinstein Institute for Medical Research, Manhasset, New York; Emory University School of Medicine, Division of Rheumatology, Atlanta, Georgia; Medical University of South Carolina, Charleston, South Carolina; University of California San Diego School of Medicine (UCSD), La Jolla, California; Hospital for Joint Diseases, New York University (NYU), Seligman Center for Advanced Therapeutics, New York, New York, USA; Autoimmune Diseases Research Unit, Department of Internal Medicine, BioCruces Health Research Institute, Hospital Universitario Cruces, University of the Basque Country, Barakaldo; Josep Font Autoimmune Diseases Laboratory, IDIBAPS, Department of Autoimmune Diseases, Hospital Clínic, Barcelona, Spain; Division of Rheumatology, Department of Internal Medicine, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey; Unit for Clinical Therapy Research (ClinTRID), Karolinska Institute, Stockholm; Department of Clinical Sciences Lund, Rheumatology, Lund University, Lund, Sweden; Copenhagen Lupus and Vasculitis Clinic, Section 4242, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. Funding for this work was provided by the Nova Scotia Health Authority Research Fund. Dr. Bae's work was supported in part by NRF-2017M3A9B4050335, Republic of Korea. Dr. Gordon's work was supported by Lupus UK and the NIHR/Wellcome Trust Clinical Research Facility. The Montreal General Hospital Lupus Clinic is partially supported by the Singer Family Fund for Lupus Research. Dr. Clarke holds The Arthritis Society Chair in Rheumatic Diseases at the University of Calgary. Dr. Fortin presently holds a tier 1 Canada Research Chair on Systemic Autoimmune Rheumatic Diseases at Université Laval, and part of this work was done while he was still a Distinguished Senior Investigator of The Arthritis Society. Dr. Bruce is an NIHR Senior Investigator and is supported by Arthritis Research UK, the NIHR Manchester Biomedical Centre, and the NIHR/Wellcome Trust Manchester Clinical Research Facility. The views expressed in this publication are those of the author(s) and not necessarily those of the NHS, the NIHR, or the Department of Health. Dr. Isenberg and Dr. Rahman are supported by the NIHR University College London Hospitals Biomedical Research Center. The Hopkins Lupus Cohort is supported by the US National Institutes of Health (NIH; grant AR43727 and 69572). Dr. Dooley's work was supported by the NIH (grant RR00046). Dr. Ramsey-Goldman's work was supported by the NIH (grants 5UL1TR001422-02, formerly 8UL1TR000150 and UL-1RR-025741, K24-AR-02318, and P60AR064464 formerly P60-AR-48098). Dr. Ruiz-Irastorza is supported by the Department of Education, Universities and Research of the Basque Government. Dr. Jacobsen is supported by the Danish Rheumatism Association (A3865) and the Novo Nordisk Foundation (A05990). Dr. Hanly is supported by the Canadian Institutes of Health Research (grant MOP-88526). A. Legge, MD, Department of Medicine, Division of Rheumatology, Dalhousie University; S. Kirkland, PhD, Department of Community Health and Epidemiology, Dalhousie University; K. Rockwood, MD, Division of Geriatric Medicine, Department of Medicine, Dalhousie University; P. Andreou, PhD, Department of Community Health and Epidemiology, Dalhousie University; S.C. Bae, MD, Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases; C. Gordon, MD, Rheumatology Research Group, School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham; J. Romero-Diaz, MD, Instituto Nacional de Ciencias Medicas y Nutrición; J. Sanchez-Guerrero, MD, Instituto Nacional de Ciencias Medicas y Nutrición; D.J. Wallace, MD, Cedars-Sinai/David Geffen School of Medicine at UCLA; S. Bernatsky, MD, Divisions of Rheumatology and Clinical Epidemiology, Department of Medicine, McGill University; A.E. Clarke, MD, Division of Rheumatology, Cumming School of Medicine, University of Calgary; J.T. Merrill, MD, Department of Clinical Pharmacology, Oklahoma Medical Research Foundation; E.M. Ginzler, MD, Department of Medicine, SUNY Downstate Medical Center; P. Fortin, MD, Division of Rheumatology, CHU de Québec et Université Laval, D.D. Gladman, MD, Center for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital and University of Toronto; M.B. Urowitz, MD, Center for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital and University of Toronto; I.N. Bruce, MD, Arthritis Research UK Epidemiology Unit, Faculty of Biology Medicine and Health, Manchester Academic Health Sciences Center, The University of Manchester, and NIHR Manchester Musculoskeletal Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Center; D.A. Isenberg, MD, Center for Rheumatology, Department of Medicine, University College London; A. Rahman, MD, Center for Rheumatology, Department of Medicine, University College London; G.S. Alarcón, MD, Department of Medicine, University of Alabama at Birmingham; M. Petri, MD, Division of Rheumatology, Johns Hopkins University School of Medicine; M.A. Khamashta, MD, Lupus Research Unit, The Rayne Institute, St Thomas' Hospital, King's College London School of Medicine; M.A. Dooley, MD, Thurston Arthritis Research Center, University of North Carolina; R. Ramsey-Goldman, MD, Northwestern University and Feinberg School of Medicine; S. Manzi, MD, Lupus Center of Excellence, Allegheny Health Network; A.A. Zoma, MD, Lanarkshire Center for Rheumatology, Hairmyres Hospital; C. Aranow, MD, Feinstein Institute for Medical Research; M. Mackay, MD, Feinstein Institute for Medical Research; G. Ruiz-Irastorza, MD, Autoimmune Diseases Research Unit, Department of Internal Medicine, BioCruces Health Research Institute, Hospital Universitario Cruces, University of the Basque Country; S.S. Lim, MD, Emory University School of Medicine, Division of Rheumatology; M. Inanc, MD, Division of Rheumatology, Department of Internal Medicine, Istanbul Medical Faculty, Istanbul University; R.F. van Vollenhoven, MD, ClinTRID, Karolinska Institute; A. Jonsen, MD, Department of Clinical Sciences Lund, Rheumatology, Lund University; O. Nived, MD, Department of Clinical Sciences Lund, Rheumatology, Lund University; M. Ramos-Casals, MD, Josep Font Autoimmune Diseases Laboratory, IDIBAPS, Department of Autoimmune Diseases, Hospital Clínic; D.L. Kamen, MD, Medical University of South Carolina; K.C. Kalunian, MD, UCSD School of Medicine; S. Jacobsen, MD, Copenhagen Lupus and Vasculitis Clinic, Section 4242, Rigshospitalet, Copenhagen University Hospital; C.A. Peschken, MD, University of Maniptoba; A. Askanase, MD, Hospital for Joint Diseases, NYU, Seligman Center for Advanced Therapeutics; J.G. Hanly, MD, Division of Rheumatology, Department of Medicine and Department of Pathology, Queen Elizabeth II Health Sciences Center and Dalhousie University. Address correspondence to Dr. J.G. Hanly, Division of Rheumatology, Nova Scotia Rehabilitation Centre (2nd Floor), 1341 Summer St., Halifax, Nova Scotia B3H 4K4, Canada. E-mail: Accepted for publication March 27, 2019.

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http://www.jrheum.org/lookup/doi/10.3899/jrheum.181338
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http://dx.doi.org/10.3899/jrheum.181338DOI Listing
April 2019

Evaluating duration of response to treatment in systemic lupus erythematosus clinical trials.

Lupus Sci Med 2018 6;5(1):e000266. Epub 2018 Aug 6.

Department of Medicine, New York University School of Medicine, New York City, New York, USA.

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http://dx.doi.org/10.1136/lupus-2018-000266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088344PMC
August 2018

A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus.

Hum Mol Genet 2018 Jul;27(13):2392-2404

Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1093/hmg/ddy140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005081PMC
July 2018

New Trials in Lupus and where Are we Going.

Curr Rheumatol Rep 2018 05 3;20(6):34. Epub 2018 May 3.

Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, 825 NE 13th Street, MS 22, Oklahoma City, OK, 73104, USA.

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http://dx.doi.org/10.1007/s11926-018-0745-1DOI Listing
May 2018

Two-year Efficacy and Safety of Subcutaneous Tocilizumab in Combination with Disease-modifying Antirheumatic Drugs Including Escalation to Weekly Dosing in Rheumatoid Arthritis.

J Rheumatol 2018 04 15;45(4):456-464. Epub 2017 Dec 15.

From the Altoona Center for Clinical Research, Duncansville, Pennsylvania; University of Nevada School of Medicine, Las Vegas, Nevada; Clinical Research Center of Reading, Reading, Pennsylvania; Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma; Genentech, South San Francisco, California, USA; Universidad Autónoma de Chihuahua, Chihuahua; Centro de Investigacion en Enfermedades Reumaticas, Mexicali, Baja California, Mexico; Hospital Virgen Macarena, Servicio de Reumatología, Sevilla, Spain; Universidade Federal do Paraná, Curitiba, Brazil; Roche Pharmaceuticals, Welwyn Garden City, London, UK; St. Joseph's Health Centre, Western University, London, Ontario, Canada.

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http://dx.doi.org/10.3899/jrheum.161539DOI Listing
April 2018

Editorial: Lupus, the Chameleon: Many Disguises Difficult to Capture.

Arthritis Rheumatol 2017 10 10;69(10):1921-1924. Epub 2017 Sep 10.

Oklahoma Medical Research Foundation, Oklahoma City.

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http://dx.doi.org/10.1002/art.40190DOI Listing
October 2017

Transancestral mapping and genetic load in systemic lupus erythematosus.

Authors:
Carl D Langefeld Hannah C Ainsworth Deborah S Cunninghame Graham Jennifer A Kelly Mary E Comeau Miranda C Marion Timothy D Howard Paula S Ramos Jennifer A Croker David L Morris Johanna K Sandling Jonas Carlsson Almlöf Eduardo M Acevedo-Vásquez Graciela S Alarcón Alejandra M Babini Vicente Baca Anders A Bengtsson Guillermo A Berbotto Marc Bijl Elizabeth E Brown Hermine I Brunner Mario H Cardiel Luis Catoggio Ricard Cervera Jorge M Cucho-Venegas Solbritt Rantapää Dahlqvist Sandra D'Alfonso Berta Martins Da Silva Iñigo de la Rúa Figueroa Andrea Doria Jeffrey C Edberg Emőke Endreffy Jorge A Esquivel-Valerio Paul R Fortin Barry I Freedman Johan Frostegård Mercedes A García Ignacio García de la Torre Gary S Gilkeson Dafna D Gladman Iva Gunnarsson Joel M Guthridge Jennifer L Huggins Judith A James Cees G M Kallenberg Diane L Kamen David R Karp Kenneth M Kaufman Leah C Kottyan László Kovács Helle Laustrup Bernard R Lauwerys Quan-Zhen Li Marco A Maradiaga-Ceceña Javier Martín Joseph M McCune David R McWilliams Joan T Merrill Pedro Miranda José F Moctezuma Swapan K Nath Timothy B Niewold Lorena Orozco Norberto Ortego-Centeno Michelle Petri Christian A Pineau Bernardo A Pons-Estel Janet Pope Prithvi Raj Rosalind Ramsey-Goldman John D Reveille Laurie P Russell José M Sabio Carlos A Aguilar-Salinas Hugo R Scherbarth Raffaella Scorza Michael F Seldin Christopher Sjöwall Elisabet Svenungsson Susan D Thompson Sergio M A Toloza Lennart Truedsson Teresa Tusié-Luna Carlos Vasconcelos Luis M Vilá Daniel J Wallace Michael H Weisman Joan E Wither Tushar Bhangale Jorge R Oksenberg John D Rioux Peter K Gregersen Ann-Christine Syvänen Lars Rönnblom Lindsey A Criswell Chaim O Jacob Kathy L Sivils Betty P Tsao Laura E Schanberg Timothy W Behrens Earl D Silverman Marta E Alarcón-Riquelme Robert P Kimberly John B Harley Edward K Wakeland Robert R Graham Patrick M Gaffney Timothy J Vyse

Nat Commun 2017 07 17;8:16021. Epub 2017 Jul 17.

Divisions of Genetics and Molecular Medicine and Immunology, Infection and Inflammatory Diseases, King's College London, Guy's Hospital, London SE1 9RT, UK.

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http://dx.doi.org/10.1038/ncomms16021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520018PMC
July 2017

Pathways of impending disease flare in African-American systemic lupus erythematosus patients.

J Autoimmun 2017 03 2;78:70-78. Epub 2017 Feb 2.

Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, OK, 73104, USA; Departments of Medicine and Pathology, Oklahoma Clinical and Translational Science Institute, University of Oklahoma Health Sciences Center, 940 Stanton L. Young Boulevard, BMSB 451, Oklahoma City, OK, 73104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2016.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340190PMC
March 2017

Why, why, why de-lupus (does so badly in clinical trials).

Expert Rev Clin Immunol 2016 19;12(2):95-8. Epub 2016 Jan 19.

b Clinical Pharmacology Research Program , Oklahoma Medical Research Foundation , Oklahoma City , OK , USA.

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http://dx.doi.org/10.1586/1744666X.2016.1112270DOI Listing
November 2016

Impact of heart rate variability, a marker for cardiac health, on lupus disease activity.

Arthritis Res Ther 2016 09 2;18:197. Epub 2016 Sep 2.

Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, 825 N.E. 13th Street, Oklahoma City, OK, 73104, USA.

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http://dx.doi.org/10.1186/s13075-016-1087-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010705PMC
September 2016

X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome.

Arthritis Rheumatol 2016 05;68(5):1290-1300

College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.

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http://dx.doi.org/10.1002/art.39560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019501PMC
May 2016

DNA methylation patterns in naïve CD4+ T cells identify epigenetic susceptibility loci for malar rash and discoid rash in systemic lupus erythematosus.

Lupus Sci Med 2015 15;2(1):e000101. Epub 2015 Sep 15.

Division of Rheumatology, Department of Internal Medicine , University of Michigan , Ann Arbor, Michigan , USA ; Center for Computational Medicine and Bioinformatics, University of Michigan , Ann Arbor, Michigan , USA.

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http://dx.doi.org/10.1136/lupus-2015-000101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577980PMC
September 2015

Connective tissue diseases: Is SLE many single-organ diseases or an overlapping spectrum?

Authors:
Joan T Merrill

Nat Rev Rheumatol 2015 Jul 5;11(7):385-6. Epub 2015 May 5.

Clinical Pharmacology Research Program, Oklahoma Medical Research Foundation, 825 NE 13th Street, MS 22, Oklahoma City, OK 73104, USA.

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http://dx.doi.org/10.1038/nrrheum.2015.61DOI Listing
July 2015

Renal involvement in lupus is characterized by unique DNA methylation changes in naïve CD4+ T cells.

J Autoimmun 2015 Jul 23;61:29-35. Epub 2015 May 23.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2015.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497927PMC
July 2015

A highlight from the LUPUS 2014 meeting: eight great ideas.

Lupus Sci Med 2015 30;2(1):e000087. Epub 2015 Jun 30.

Departments of Medicine and Immunology , University of Washington , Seattle, Washington , USA.

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http://dx.doi.org/10.1136/lupus-2015-000087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493165PMC
July 2015

Differential expression of the transcription factor ARID3a in lupus patient hematopoietic progenitor cells.

J Immunol 2015 Feb 22;194(3):940-9. Epub 2014 Dec 22.

Immunobiology and Cancer Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104; Microbiology and Immunology Program, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104; Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104

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http://dx.doi.org/10.4049/jimmunol.1401941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297684PMC
February 2015

The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.

Hum Mol Genet 2015 Jan 8;24(2):582-96. Epub 2014 Sep 8.

Division of Rheumatology, Center for Autoimmune Genomics and Etiology and US Department of Veterans Affairs Medical Center, Cincinnati, OH, USA.

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http://dx.doi.org/10.1093/hmg/ddu455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275071PMC
January 2015

How should lupus flares be measured? Deconstruction of the safety of estrogen in lupus erythematosus national assessment-systemic lupus erythematosus disease activity index flare index.

Rheumatology (Oxford) 2014 Dec 11;53(12):2175-81. Epub 2014 Apr 11.

Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Department of Internal Medicine, Section of Rheumatology, University of Oklahoma Health Science Center and Clinical Pharmacology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.

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http://dx.doi.org/10.1093/rheumatology/keu153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542656PMC
December 2014

Disease activity in systemic lupus erythematosus correlates with expression of the transcription factor AT-rich-interactive domain 3A.

Arthritis Rheumatol 2014 Dec;66(12):3404-12

Oklahoma Medical Research Foundation and Oklahoma University Health Sciences Center, Oklahoma City.

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http://dx.doi.org/10.1002/art.38857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245462PMC
December 2014

Which outcome measures in SLE clinical trials best reflect medical judgment?

Lupus Sci Med 2014 1;1(1):e000005. Epub 2014 Apr 1.

Oklahoma Medical Research Foundation , Oklahoma City, Oklahoma , USA.

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http://lupus.bmj.com/lookup/doi/10.1136/lupus-2013-000005
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http://dx.doi.org/10.1136/lupus-2013-000005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225744PMC
November 2014

A 2014 update on the management of patients with systemic lupus erythematosus.

Semin Arthritis Rheum 2014 Oct 30;44(2):e1-2. Epub 2014 Sep 30.

Section of Rheumatology, Department of Medicine, University of Chicago, Chicago, IL.

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https://linkinghub.elsevier.com/retrieve/pii/S00490172140022
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http://dx.doi.org/10.1016/j.semarthrit.2014.09.013DOI Listing
October 2014

American College of Rheumatology criteria at inception, and accrual over 5 years in the SLICC inception cohort.

J Rheumatol 2014 May 1;41(5):875-80. Epub 2014 Apr 1.

From the Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital and University of Toronto, Toronto, Ontario, Canada; Instituto Nacional de Ciencias Medicas y Nutricion, Mexico City, Mexico; Rheumatology Research Group, School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK; Department of Rheumatology, Hospital for Rheumatic Diseases and Hanyang University Medical Center, Seoul, Korea; Divisions of Clinical Immunology/Allergy and Clinical Epidemiology, Montreal General Hospital and McGill University Health Centre, Montreal, Quebec, Canada; Centre Hospitalier Universitaire de Québec et Université Laval, Quebec City, Quebec, Canada; Division of Rheumatology, Department of Medicine and Department of Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada; Centre for Rheumatology Research, University College, London, UK; Cedars-Sinai/David Geffen School of Medicine, University of California, Los Angeles, California, USA; Department of Medicine, State University of New York Downstate Medical Center, Brooklyn, New York, USA; Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK; Department of Clinical Pharmacology, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA; Department of Rheumatology, University Hospital Lund, Lund, Sweden; Division of Rheumatology and Immunology, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA; Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama, Birmingham, Alabama, USA; Center for Rheumatology Research, Landspitali University Hospital, Reyjkavik, Iceland; Northwestern University and Feinber

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http://dx.doi.org/10.3899/jrheum.130704DOI Listing
May 2014

Disease control and safety of belimumab plus standard therapy over 7 years in patients with systemic lupus erythematosus.

J Rheumatol 2014 Feb 1;41(2):300-9. Epub 2013 Nov 1.

From the State University of New York (SUNY) Downstate Medical Center, Brooklyn, New York; Cedars-Sinai Medical Center/David Geffen School of Medicine at the University of California at Los Angeles; Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma; North Shore-Long Island Jewish Health System, Lake Success, New York; Los Angeles County + University of Southern California Medical Center and University of Southern California Keck School of Medicine, Los Angeles, California; University of Alabama at Birmingham, Alabama; MedStar Washington Hospital Center, Washington, DC; Oklahoma Center for Arthritis Therapy and Research, Tulsa, Oklahoma; University of Michigan, Ann Arbor, Michigan; Human Genome Sciences Inc., Rockville; Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://www.jrheum.org/cgi/doi/10.3899/jrheum.121368
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http://dx.doi.org/10.3899/jrheum.121368DOI Listing
February 2014

Treatment of systemic lupus erythematosus: new therapeutic avenues and blind alleys.

Nat Rev Rheumatol 2014 Jan 8;10(1):23-34. Epub 2013 Oct 8.

Clinical Pharmacology Research Program, Oklahoma Medical Research Foundation, 825 NE 13th Street, MS 22, Oklahoma City, OK 73104, USA.

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http://dx.doi.org/10.1038/nrrheum.2013.145DOI Listing
January 2014

Herpes zoster vaccination in SLE: a pilot study of immunogenicity.

J Rheumatol 2013 Nov 15;40(11):1875-80. Epub 2013 Sep 15.

From Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA.

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http://dx.doi.org/10.3899/jrheum.130170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867792PMC
November 2013

Co-stimulatory molecules as targets for treatment of lupus.

Authors:
Joan T Merrill

Clin Immunol 2013 Sep 29;148(3):369-75. Epub 2013 Apr 29.

Clinical Pharmacology Research Program, Oklahoma Medical Research Foundation, University of Oklahoma, 825 NE 13th St, Oklahoma City, OK 73107, USA.

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September 2013