Publications by authors named "Joachim Weischenfeldt"

39Publications

Identification of unique and shared mitochondrial DNA mutations in neurodegeneration and cancer by single-cell mitochondrial DNA structural variation sequencing (MitoSV-seq).

EBioMedicine 2020 Jul 3;57:102868. Epub 2020 Jul 3.

Neuroinflammation Unit, Biotech Research and Innovation Centre, Faculty of Health and Medical Sciences, University of Copenhagen, Ole Maaløes Vej 5, DK-2200 Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2020.102868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334819PMC
July 2020

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes.

Nature 2020 02 5;578(7793):102-111. Epub 2020 Feb 5.

The Broad Institute of MIT and Harvard, Cambridge, MA, USA.

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http://dx.doi.org/10.1038/s41586-020-1965-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054214PMC
February 2020

Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability.

J Cell Biol 2019 12 15;218(12):3943-3953. Epub 2019 Oct 15.

Protein Signaling Program, Novo Nordisk Foundation Center for Protein Research, Copenhagen, Denmark

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http://dx.doi.org/10.1083/jcb.201905064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891097PMC
December 2019

Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories.

Cancer Cell 2018 12;34(6):996-1011.e8

Finsen Laboratory, Rigshospitalet, DK-2200, Copenhagen, Denmark; Biotech Research & Innovation Centre (BRIC), University of Copenhagen, DK-2200, Copenhagen, Denmark; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, 69120 Heidelberg, Germany; Charité Universitätsmedizin Berlin, Charitéplatz 1, D-10117 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.10.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444093PMC
December 2018

Author Correction: The landscape of genomic alterations across childhood cancers.

Nature 2018 07;559(7714):E10

Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41586-018-0167-2DOI Listing
July 2018

Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.

Lancet Oncol 2018 06 9;19(6):785-798. Epub 2018 May 9.

Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany; Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany; Hopp Children's Cancer Center at the NCT Heidelberg, Heidelberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14702045183024
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http://dx.doi.org/10.1016/S1470-2045(18)30242-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984248PMC
June 2018

The landscape of genomic alterations across childhood cancers.

Nature 2018 03 28;555(7696):321-327. Epub 2018 Feb 28.

Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature25480DOI Listing
March 2018

The whole-genome landscape of medulloblastoma subtypes.

Nature 2017 07;547(7663):311-317

Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature22973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905700PMC
July 2017

Genomes of early onset prostate cancer.

Curr Opin Urol 2017 Sep;27(5):481-487

aBiotech Research & Innovation Centre (BRIC) and Finsen Laboratory, Rigshospitalet, Copenhagen, Denmark bEuropean Molecular Biology Laboratory (EMBL), Heidelberg, Germany.

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http://dx.doi.org/10.1097/MOU.0000000000000422DOI Listing
September 2017

The aging prostate is never "normal": implications from the genomic characterization of multifocal prostate cancers.

Eur Urol 2015 Sep 22;68(3):348-50. Epub 2015 Apr 22.

Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1016/j.eururo.2015.04.012DOI Listing
September 2015

Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer.

Cell Rep 2014 Aug 24;8(3):798-806. Epub 2014 Jul 24.

Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; The German Cancer Consortium, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.06.053DOI Listing
August 2014

Phenotypic impact of genomic structural variation: insights from and for human disease.

Nat Rev Genet 2013 Feb;14(2):125-38

Genome Biology Unit, European Molecular Biology Laboratory, Meyerhofstrasse 1, Heidelberg, 69117, Germany.

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http://www.nature.com/articles/nrg3373
Publisher Site
http://dx.doi.org/10.1038/nrg3373DOI Listing
February 2013

Dissecting the genomic complexity underlying medulloblastoma.

Nature 2012 Aug;488(7409):100-5

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany.

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http://dx.doi.org/10.1038/nature11284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662966PMC
August 2012

Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patterns.

Genome Biol 2012 May 24;13(5):R35. Epub 2012 May 24.

The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, DK2200 Copenhagen, Denmark.

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http://dx.doi.org/10.1186/gb-2012-13-5-r35DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446288PMC
May 2012

Bone Marrow-Derived Macrophages (BMM): Isolation and Applications.

CSH Protoc 2008 Dec 1;2008:pdb.prot5080. Epub 2008 Dec 1.

The Biotech Research and Innovation Centre, University of Copenhagen, 2200 Copenhagen, Denmark.

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http://dx.doi.org/10.1101/pdb.prot5080DOI Listing
December 2008

Messenger RNA surveillance: neutralizing natural nonsense.

Curr Biol 2005 Jul;15(14):R559-62

Section of Gene Therapy Research, Copenhagen University Hospital, Juliane Mariesvej 20 section 9322, DK-2100 Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.cub.2005.07.002DOI Listing
July 2005