Joachim Fandrey

Joachim Fandrey

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Joachim Fandrey

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Things get broken: the hypoxia-inducible factor prolyl hydroxylases in ischemic heart disease.

Basic Res Cardiol 2019 03 11;114(3):16. Epub 2019 Mar 11.

Institute of Physiology, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1007/s00395-019-0725-2DOI Listing
March 2019

Fluorescence Lifetime Imaging Microscopy (FLIM) as a Tool to Investigate Hypoxia-Induced Protein-Protein Interaction in Living Cells.

Methods Mol Biol 2018 ;1742:45-53

Institute of Physiology, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1007/978-1-4939-7665-2_5DOI Listing
January 2019

Sphingolipids in inflammatory hypoxia.

Biol Chem 2018 09;399(10):1169-1174

Institut für Physiologie, Universität Duisburg-Essen, D-45122 Essen, Germany.

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http://www.degruyter.com/view/j/bchm.2018.399.issue-10/hsz-2
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http://dx.doi.org/10.1515/hsz-2018-0173DOI Listing
September 2018

Optical analysis of cellular oxygen sensing.

Exp Cell Res 2017 07 8;356(2):122-127. Epub 2017 Mar 8.

Institute of Physiology, University of Duisburg-Essen, Essen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2017.03.009DOI Listing
July 2017

Optical Analysis of Hypoxia Inducible Factor (HIF)-1 Complex Assembly: Imaging of Cellular Oxygen Sensing.

Adv Exp Med Biol 2016 ;903:247-58

Institut für Physiologie, Universität Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1007/978-1-4899-7678-9_17DOI Listing
June 2017

Hypoxia-Dependent HIF-1 Activation Impacts on Tissue Remodeling in Graves' Ophthalmopathy-Implications for Smoking.

J Clin Endocrinol Metab 2016 12 9;101(12):4834-4842. Epub 2016 Sep 9.

Molecular Ophthalmology (G.-E.G., M.H., B.A., A.E., U.B.-P.), Department of Ophthalmology, University of Duisburg-Essen, 45147 Essen, Germany; and Institute of Physiology (B.D.R., J.F.), University of Duisburg-Essen, 45147 Essen, Germany.

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http://dx.doi.org/10.1210/jc.2016-1279DOI Listing
December 2016

Dendritic Cells under Hypoxia: How Oxygen Shortage Affects the Linkage between Innate and Adaptive Immunity.

J Immunol Res 2016 4;2016:5134329. Epub 2016 Feb 4.

Institut für Physiologie, Universität Duisburg-Essen, Hufelandstrasse 55, 45122 Essen, Germany.

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http://dx.doi.org/10.1155/2016/5134329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757696PMC
November 2016

Dose-dependent effects of levetiracetam after hypoxia and hypothermia in the neonatal mouse brain.

Brain Res 2016 09 20;1646:116-124. Epub 2016 May 20.

Department of Pediatrics 1, Neonatology, Un iversity Hospital Essen, University Duisburg, Essen, Germany.

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http://dx.doi.org/10.1016/j.brainres.2016.05.040DOI Listing
September 2016

Mitochondrial DNA: An Endogenous Trigger for Immune Paralysis.

Anesthesiology 2016 Apr;124(4):923-33

From the Klinik für Anästhesiologie und Intensivmedizin, Universität Duisburg-Essen and Universitätsklinikum Essen, Essen, Germany (S.T.S., M.A., A.E., N.S., J.W., J.P.); Institut für molekulare Medizin und experimentelle Immunologie, Universität Bonn, Bonn, Germany (L.F., C.K.); Klinik für Anästhesiologie und operative Intensivmedizin, Knappschaftskrankenhaus Bochum und Ruhruniversität Bochum, Bochum, Germany (M.A.); Institut für Medizinische Mikrobiologie, Immunologie und Parasitologie, Universität Bonn, Bonn, Germany (B.S.); Klinische Epidemiologie, Integriertes Forschungs- und Behandlungszentrum (IFB) Sepsis und Sepsisfolgen - Center for Sepsis Control and Care (CSCC), Universitätsklinikum Jena, Jena, Germany (A.S.); Klinik und Poliklinik für Dermatologie und Allergologie, Universität Bonn, Bonn, Germany (S.K., T.B.); Institut für Pathologie, Universität Duisburg-Essen and Universitätsklinikum Essen, Essen, Germany (H.A.B.); Institut für Medizinische Mikrobiologie, Universität Duisburg-Essen and Universitätsklinikum Essen, Essen, Germany (J.S., A.M.W.); Institut für Physiologie, Universität Duisburg-Essen, Essen, Germany (J.F., S.F.); Klinik und Poliklinik für Anästhesiologie und operative Intensivmedizin, Universitätsklinikum Bonn, Bonn, Germany (S.F.); and Klinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn, Bonn, Germany (A.L.).

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http://dx.doi.org/10.1097/ALN.0000000000001008DOI Listing
April 2016

Oxygen sensing in intestinal mucosal inflammation.

Pflugers Arch 2016 Jan 25;468(1):77-84. Epub 2015 Jul 25.

Institut für Physiologie, Universität Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1007/s00424-015-1722-4DOI Listing
January 2016

Measurement of ROS Levels and Membrane Potential Dynamics in the Intact Carotid Body Ex Vivo.

Adv Exp Med Biol 2015 ;860:55-9

Institute of Physiology, University of Duisburg-Essen, Hufelandstr. 55, 45122, Essen, Germany,

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http://dx.doi.org/10.1007/978-3-319-18440-1_7DOI Listing
January 2016

Potential role of hypoxia in early stages of Hodgkin lymphoma pathogenesis.

Haematologica 2015 Oct 9;100(10):1320-6. Epub 2015 Jul 9.

Institute of Cell Biology (Cancer Research), Medical Faculty, University of Duisburg-Essen, Essen

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http://dx.doi.org/10.3324/haematol.2015.127498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591764PMC
October 2015

Measuring oxygen levels in Caco-2 cultures.

Hypoxia (Auckl) 2015 9;3:53-66. Epub 2015 Oct 9.

Department of Physiological Chemistry, University of Veterinary Medicine Hannover; Research Center for Emerging Infections and Zoonoses (RIZ), University of Veterinary Medicine, Hannover, Germany.

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http://dx.doi.org/10.2147/HP.S85625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045089PMC
October 2015

Hypoxia induced gene expression: the specificity switch!

Cell Cycle 2015 ;14(10):1491

a Institut für Physiologie; Universität Duisburg-Essen ; Essen , Germany.

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http://dx.doi.org/10.1080/15384101.2015.1024587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614514PMC
September 2015

Acupuncture-brain interactions as hypothesized by mood scale recordings.

Med Hypotheses 2015 Sep 22;85(3):371-9. Epub 2015 May 22.

Forschungsinstitut für Notfallmedizin und Gesundheit, Dortmund, Germany.

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http://dx.doi.org/10.1016/j.mehy.2015.05.013DOI Listing
September 2015

Severe blunt muscle trauma in rats: only marginal hypoxia in the injured area.

PLoS One 2014 31;9(10):e111151. Epub 2014 Oct 31.

University of Duisburg-Essen, Institute of Physiological Chemistry, University Hospital Essen, Essen, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111151PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215885PMC
July 2015

Resolution of liver fibrosis requires myeloid cell-driven sinusoidal angiogenesis.

Hepatology 2015 Jun 10;61(6):2042-55. Epub 2015 Mar 10.

Institut National de la Santé et de la Recherche Médicale (INSERM), Unit 970, Paris Cardiovascular Research Center, Paris, France.

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http://dx.doi.org/10.1002/hep.27635DOI Listing
June 2015

Rounding up the usual suspects in O2 sensing: CO, NO, and H2S!

Authors:
Joachim Fandrey

Sci Signal 2015 Apr 21;8(373):fs10. Epub 2015 Apr 21.

Institut für Physiologie, Universität Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1126/scisignal.aab1665DOI Listing
April 2015

Myeloid hypoxia-inducible factor-1α is essential for skeletal muscle regeneration in mice.

J Immunol 2013 Jul 31;191(1):407-14. Epub 2013 May 31.

Institut für Physiologie, Universität Duisburg-Essen, D-45122 Essen, Germany.

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http://dx.doi.org/10.4049/jimmunol.1103779DOI Listing
July 2013

Hypoxia-inducible factor and target gene expression are decreased in patients with sepsis: prospective observational clinical and cellular studies.

Anesthesiology 2013 Jun;118(6):1426-36

Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Essen and Universität Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1097/ALN.0b013e31828baa67DOI Listing
June 2013

Role of hypoxia inducible factor-1α for interferon synthesis in mouse dendritic cells.

Biol Chem 2013 Apr;394(4):495-505

Institut für Physiologie, Universität Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1515/hsz-2012-0320DOI Listing
April 2013

Highlight: sensing hypoxia in the cell and the organism.

Authors:
Joachim Fandrey

Biol Chem 2013 Apr;394(4):433-4

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http://dx.doi.org/10.1515/hsz-2013-0132DOI Listing
April 2013

Why not the liver instead of the kidney?

Authors:
Joachim Fandrey

Blood 2012 Aug;120(9):1760-1

Universität Duisburg-essen.

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http://dx.doi.org/10.1182/blood-2012-06-433201DOI Listing
August 2012

Role of reactive oxygen species in the regulation of HIF-1 by prolyl hydroxylase 2 under mild hypoxia.

Free Radic Res 2012 Jun 3;46(6):705-17. Epub 2012 Apr 3.

Institut für Physiologie, Universität Duisburg-Essen, Germany.

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http://dx.doi.org/10.3109/10715762.2012.669041DOI Listing
June 2012

Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling.

Nucleic Acids Res 2012 Mar 10;40(5):1928-43. Epub 2011 Nov 10.

Institute of Physiology and Zürich Center for Integrative Human Physiology (ZIHP), University of Zürich, 8057 Zürich, Switzerland.

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http://dx.doi.org/10.1093/nar/gkr978DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3300025PMC
March 2012

Multifocal animated imaging of changes in cellular oxygen and calcium concentrations and membrane potential within the intact adult mouse carotid body ex vivo.

Am J Physiol Cell Physiol 2011 Aug 27;301(2):C266-71. Epub 2011 Apr 27.

Department of Physiology, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1152/ajpcell.00508.2010DOI Listing
August 2011

Activation of hypoxia-inducible factor 1 in skeletal muscle cells after exposure to damaged muscle cell debris.

Shock 2011 Jun;35(6):632-8

Institute of Biochemistry I, Goethe-University Frankfurt, Frankfurt, Germany.

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http://dx.doi.org/10.1097/SHK.0b013e3182111f3dDOI Listing
June 2011

Oxygen-regulated expression of the erythropoietin gene in the human renal cell line REPC.

Blood 2011 May 15;117(18):4905-14. Epub 2011 Mar 15.

Institut für Physiologie, Universität Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1182/blood-2010-07-298083DOI Listing
May 2011

Role of N-acetyl-N-nitroso-tryptophan as nitric oxide donor in the modulation of HIF-1-dependent signaling.

Biol Chem 2010 May;391(5):533-40

Institut für Physiologie, Universität Duisburg-Essen, Germany.

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http://dx.doi.org/10.1515/BC.2010.054DOI Listing
May 2010

More insights into the CCN3/Connexin43 interaction complex and its role for signaling.

J Cell Biochem 2010 May;110(1):129-40

Institute of Molecular Biology, University of Duisburg-Essen, Hufelandstrasse 55, D-45122 Essen, Germany.

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http://dx.doi.org/10.1002/jcb.22519DOI Listing
May 2010

Oxygen-sensing under the influence of nitric oxide.

Cell Signal 2010 Mar;22(3):349-56

Institut für Physiologie, Universität Duisburg-Essen, Hufelandstr. 55, 45122 Essen.

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http://dx.doi.org/10.1016/j.cellsig.2009.10.004DOI Listing
March 2010

Nanoscopy of the cellular response to hypoxia by means of fluorescence resonance energy transfer (FRET) and new FRET software.

PMC Biophys 2010 Mar 5;3(1). Epub 2010 Mar 5.

Institut für Physiologie, Universität Duisburg-Essen, D-45122 Essen, Germany.

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http://dx.doi.org/10.1186/1757-5036-3-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846870PMC
March 2010

Monitoring of cellular responses to hypoxia.

Methods Mol Biol 2010 ;591:243-55

Institut für Physiologie, Universität Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1007/978-1-60761-404-3_15DOI Listing
February 2010

Glycine pretreatment ameliorates liver injury after partial hepatectomy in the rat.

J Invest Surg 2010 Feb;23(1):12-20

Department of Surgery and Transplantation, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.3109/08941930903469466DOI Listing
February 2010

Combined analysis of hypoxia-inducible factor 1 alpha and metallothionein indicates an aggressive subtype of colorectal carcinoma.

Int J Colorectal Dis 2009 Nov 16;24(11):1287-96. Epub 2009 Jun 16.

Institute of Pathology and Neuropathology, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45122 Essen, Germany.

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http://dx.doi.org/10.1007/s00384-009-0753-8DOI Listing
November 2009

Molecular imaging: into in vivo interaction of HIF-1alpha and HIF-2alpha with ARNT.

Ann N Y Acad Sci 2009 Oct;1177:74-81

Institute for Physiology, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1111/j.1749-6632.2009.05029.xDOI Listing
October 2009

Hypoxia-inducible factor prolyl-4-hydroxylase PHD2 protein abundance depends on integral membrane anchoring of FKBP38.

J Biol Chem 2009 Aug 22;284(34):23046-58. Epub 2009 Jun 22.

Institute of Physiology and Zürich Center for Integrative Human Physiology (ZIHP), University of Zürich, CH-8057 Zürich, Switzerland.

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http://dx.doi.org/10.1074/jbc.M109.032631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755711PMC
August 2009

Non-hypoxic activation of the negative regulatory feedback loop of prolyl-hydroxylase oxygen sensors.

Biochem Biophys Res Commun 2009 Jul 8;384(4):519-23. Epub 2009 May 8.

Institut für Physiologie, Universität Duisburg-Essen, Hufelandstrasse 55, D-45122 Essen, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2009.05.016DOI Listing
July 2009

Oxygen sensing and the activation of the hypoxia inducible factor 1 (HIF-1)--invited article.

Adv Exp Med Biol 2009 ;648:197-206

Institut fuer Physiologie, Universitaet Duisburg-Essen, Essen, Germany.

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http://www.springerlink.com/index/10.1007/978-90-481-2259-2_
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http://dx.doi.org/10.1007/978-90-481-2259-2_23DOI Listing
July 2009

No evidence for protective erythropoietin alpha signalling in rat hepatocytes.

BMC Gastroenterol 2009 Apr 21;9:26. Epub 2009 Apr 21.

Institut für Physiologische Chemie, Universitätsklinikum Essen, Hufelandstrasse 55, D-45122 Essen, Germany.

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http://dx.doi.org/10.1186/1471-230X-9-26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678141PMC
April 2009

Two-photon imaging of cellular activities in oxygen sensing tissues.

Microsc Microanal 2008 Dec;14(6):519-25

Institut für Physiologie, Universität Duisburg-Essen, Hufelandstrasse 55, D-45122 Essen, Germany.

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http://dx.doi.org/10.1017/S1431927608080847DOI Listing
December 2008

The impact of N-nitrosomelatonin as nitric oxide donor in cell culture experiments.

J Pineal Res 2008 Nov 31;45(4):489-96. Epub 2008 Jul 31.

Institut für Physiologie, Universität Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1111/j.1600-079X.2008.00622.xDOI Listing
November 2008

Nuclear oxygen sensing: induction of endogenous prolyl-hydroxylase 2 activity by hypoxia and nitric oxide.

J Biol Chem 2008 Nov 6;283(46):31745-53. Epub 2008 Sep 6.

Institut für Physiologie, Universität Duisburg-Essen, D-45122 Essen, Germany.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M804390200
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http://dx.doi.org/10.1074/jbc.M804390200DOI Listing
November 2008

Erythropoietin receptors on tumor cells: what do they mean?

Authors:
Joachim Fandrey

Oncologist 2008 ;13 Suppl 3:16-20

Institut für Physiologie, Universität Duisburg-Essen, Hufelandstr. 55, D-45147 Essen, Germany.

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http://dx.doi.org/10.1634/theoncologist.13-S3-16DOI Listing
October 2008

Erythropoiesis--once more HIF!

Authors:
Joachim Fandrey

Blood 2008 Aug;112(4):931-2

Universitát Duisburg-Essen Institut für Physiologie.

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http://dx.doi.org/10.1182/blood-2008-05-158451DOI Listing
August 2008

Thyroid hormone induces hypoxia-inducible factor 1alpha gene expression through thyroid hormone receptor beta/retinoid x receptor alpha-dependent activation of hepatic leukemia factor.

Endocrinology 2008 May 31;149(5):2241-50. Epub 2008 Jan 31.

Institut für Physiologie, Universität Duisburg-Essen, Hufelandstrasse 55, D-45122 Essen, Germany.

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http://dx.doi.org/10.1210/en.2007-1238DOI Listing
May 2008

Regulation of hypoxia-inducible factors during inflammation.

Methods Enzymol 2007 ;435:405-19

Institut für Physiologie, Universität Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1016/S0076-6879(07)35021-0DOI Listing
February 2008

The HIF-1 response to simulated ischemia in mouse skeletal muscle cells neither enhances glycolysis nor prevents myotube cell death.

Am J Physiol Regul Integr Comp Physiol 2007 Oct 18;293(4):R1693-701. Epub 2007 Jul 18.

Institut für Physiologie, Universität Duisburg-Essen, Hufelandstr. 55, D-45122 Essen, Germany.

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http://dx.doi.org/10.1152/ajpregu.00892.2006DOI Listing
October 2007

Optical analysis of the HIF-1 complex in living cells by FRET and FRAP.

FASEB J 2007 Mar 28;21(3):700-7. Epub 2006 Dec 28.

Institut für Physiologie, Universität Duisburg-Essen, Hufelandstrasse 55, D-45122 Essen, Germany.

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http://dx.doi.org/10.1096/fj.06-6280comDOI Listing
March 2007

Nitric oxide modulates oxygen sensing by hypoxia-inducible factor 1-dependent induction of prolyl hydroxylase 2.

J Biol Chem 2007 Jan 23;282(3):1788-96. Epub 2006 Oct 23.

Institut für Physiologie, Universität Duisburg-Essen, Hufelandstrasse 55, D-45122 Essen, Germany.

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http://dx.doi.org/10.1074/jbc.M607065200DOI Listing
January 2007

A cordial affair - erythropoietin and cardioprotection.

Authors:
Joachim Fandrey

Cardiovasc Res 2006 Oct 1;72(1):1-2. Epub 2006 Aug 1.

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http://dx.doi.org/10.1016/j.cardiores.2006.07.024DOI Listing
October 2006

Hypoxia-induced erythropoietin production: a paradigm for oxygen-regulated gene expression.

Clin Exp Pharmacol Physiol 2006 Oct;33(10):968-79

Institut für Physiologie, Universität Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1111/j.1440-1681.2006.04474.xDOI Listing
October 2006

Regulating cellular oxygen sensing by hydroxylation.

Cardiovasc Res 2006 Sep 10;71(4):642-51. Epub 2006 May 10.

Institut für Physiologie, Universität Duisburg-Essen, Hufelandstrasse 55, D-45122 Essen, Germany.

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http://dx.doi.org/10.1016/j.cardiores.2006.05.005DOI Listing
September 2006

Hypoxic pulmonary vasoconstriction is/is not mediated by increased production of reactive oxygen species.

J Appl Physiol (1985) 2006 Sep;101(3):1000; author reply 1004-5

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September 2006

The good, the bad and the ugly in oxygen-sensing: ROS, cytochromes and prolyl-hydroxylases.

Cardiovasc Res 2006 Jul 22;71(2):195-207. Epub 2006 Apr 22.

Neurologisches Institut, Edinger Institut, Klinikum der J.W. Goethe Universität Frankfurt am Main, Deutschordenstr. 46, D-60528 Frankfurt, Germany.

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http://dx.doi.org/10.1016/j.cardiores.2006.04.008DOI Listing
July 2006

Bacterial lipopolysaccharide induces HIF-1 activation in human monocytes via p44/42 MAPK and NF-kappaB.

Biochem J 2006 Jun;396(3):517-27

Institut für Physiologie, Universität Duisburg-Essen Hufelandstrasse 55, D-45122 Essen, Federal Republic of Germany.

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http://dx.doi.org/10.1042/BJ20051839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1482811PMC
June 2006

Thrombopoietin production in wild-type and interleukin-6 knockout mice with acute inflammation.

J Interferon Cytokine Res 2005 Jul;25(7):407-13

Institute of Physiology, University of Luebeck, Luebeck, Germany.

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http://dx.doi.org/10.1089/jir.2005.25.407DOI Listing
July 2005

Effects of recombinant human erythropoietin (rHuEPO) on tumor control in patients with cancer-induced anemia.

Onkologie 2005 Apr 31;28(4):216-21. Epub 2005 Mar 31.

Institut für Physiologie und Pathophysiologie, Universität Mainz, Germany.

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https://www.karger.com/Article/FullText/84033
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http://dx.doi.org/10.1159/000084033DOI Listing
April 2005

Neural substrates for behaviorally conditioned immunosuppression in the rat.

J Neurosci 2005 Mar;25(9):2330-7

Department of Medical Psychology, University Duisburg-Essen, D-45122 Essen, Germany.

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http://dx.doi.org/10.1523/JNEUROSCI.4230-04.2005DOI Listing
March 2005

High-altitude polycythemia.

Authors:
Joachim Fandrey

Haematologica 2005 Jan;90(1)

Institut für Physiologie, Universitätsklinikum Essen, Hufelandstr. 55, 45122 Essen, Germany.

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January 2005

Chelation of cellular calcium modulates hypoxia-inducible gene expression through activation of hypoxia-inducible factor-1alpha.

J Biol Chem 2004 Oct 18;279(43):44976-86. Epub 2004 Aug 18.

Institut für Physiologie, Universität Duisburg-Essen, Hufelandstrasse 55, D-45122 Essen, Germany.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M313995200
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http://dx.doi.org/10.1074/jbc.M313995200DOI Listing
October 2004

Thyroid hormone induces erythropoietin gene expression through augmented accumulation of hypoxia-inducible factor-1.

Am J Physiol Regul Integr Comp Physiol 2004 Sep 20;287(3):R600-7. Epub 2004 May 20.

Institut für Physiologie, Universitätsklinikum Essen, Universität Duisburg-Essen, Hufelandstrasse 55, D-45122 Essen, Germany.

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http://dx.doi.org/10.1152/ajpregu.00115.2004DOI Listing
September 2004

Hypoxia-induced erythropoietin expression in human neuroblastoma requires a methylation free HIF-1 binding site.

J Cell Biochem 2004 Sep;93(1):153-61

Department of Pediatric Hematology, Oncology and Endocrinology, Children's Hospital, 45122 Essen, Germany.

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http://dx.doi.org/10.1002/jcb.20133DOI Listing
September 2004

NCB5OR is a novel soluble NAD(P)H reductase localized in the endoplasmic reticulum.

J Biol Chem 2004 Jul 6;279(29):30316-25. Epub 2004 May 6.

Hematology Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1074/jbc.M402664200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045664PMC
July 2004

Oxygen and the cell.

Authors:
Joachim Fandrey

Biol Chem 2004 Mar-Apr;385(3-4):203-4

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http://dx.doi.org/10.1515/BC.2004.013DOI Listing
June 2004

Oxygen-dependent and tissue-specific regulation of erythropoietin gene expression.

Authors:
Joachim Fandrey

Am J Physiol Regul Integr Comp Physiol 2004 Jun;286(6):R977-88

Institut für Physiologie, Universität Duisburg-Essen, Hufelandstr. 55, D-45147 Essen, Germany.

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http://dx.doi.org/10.1152/ajpregu.00577.2003DOI Listing
June 2004

Altered pulmonary vascular reactivity in mice with excessive erythrocytosis.

Am J Respir Crit Care Med 2004 Apr 30;169(7):829-35. Epub 2003 Dec 30.

Department of Anesthesiology and Critical Care Medicine, University of Lübeck, Lübeck, Germany.

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http://dx.doi.org/10.1164/rccm.200308-1154OCDOI Listing
April 2004

Hepatic erythropoietin gene regulation by GATA-4.

J Biol Chem 2004 Jan 28;279(4):2955-61. Epub 2003 Oct 28.

Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida 32610, USA.

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http://dx.doi.org/10.1074/jbc.M310404200DOI Listing
January 2004

Nitric oxide impairs normoxic degradation of HIF-1alpha by inhibition of prolyl hydroxylases.

Mol Biol Cell 2003 Aug 3;14(8):3470-81. Epub 2003 May 3.

Institute of Physiology, University of Luebeck, Germany.

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http://dx.doi.org/10.1091/mbc.e02-12-0791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC181582PMC
August 2003

Thrombopoietin gene expression in the developing human central nervous system.

Brain Res Dev Brain Res 2003 Jul;143(2):217-23

Department of Neonatology, Children's Hospital, University of Bonn, Bonn, Germany.

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July 2003

Reactive oxygen species modulate HIF-1 mediated PAI-1 expression: involvement of the GTPase Rac1.

Thromb Haemost 2003 May;89(5):926-35

Experimentelle Kinderkardiologie, Deutsches Herzzentrum Müchen and der Technischen Universität Müchen, Munich, Germany.

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May 2003

Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing.

J Cell Sci 2003 Apr;116(Pt 7):1319-26

Institute of Physiology, University of Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, Germany.

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April 2003

NO and TNF-alpha released from activated macrophages stabilize HIF-1alpha in resting tubular LLC-PK1 cells.

Am J Physiol Cell Physiol 2003 Feb 25;284(2):C439-46. Epub 2002 Sep 25.

Department of Cell Biology, Faculty of Biology, University of Kaiserslautern, 67663 Kaiserslautern, Germany.

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http://dx.doi.org/10.1152/ajpcell.00294.2002DOI Listing
February 2003

Developmental changes in the expression of transcription factors GATA-1, -2 and -3 during the onset of human medullary haematopoiesis.

Br J Haematol 2002 Nov;119(2):510-5

Department of Pediatrics, University of Florida, Gainesville 32610-0296, USA.

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November 2002

Oxygen Radicals as Messengers in Oxygen-Dependent Gene Expression.

News Physiol Sci 2000 Aug;15:202-208

Institut für Biochemie und Molekulare Zellbiologie, Humboldtallee 23, 37073 Göttingen, Germany.

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August 2000