Publications by authors named "Joachim Boos"

97Publications

Bioanalysis of doxorubicin aglycone metabolites in human plasma samples-implications for doxorubicin drug monitoring.

Sci Rep 2020 10 29;10(1):18562. Epub 2020 Oct 29.

Department of Paediatric Haematology and Oncology, University Children's Hospital Muenster, Albert-Schweitzer-Campus 1, Building A1, 48149, Muenster, Germany.

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http://dx.doi.org/10.1038/s41598-020-75662-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596548PMC
October 2020

Preclinical Evaluation of Combined Topoisomerase and Proteasome Inhibition Against Pediatric Malignancies.

Anticancer Res 2018 Jul;38(7):3977-3984

Department of Pediatric Hematology and Oncology, University Children's Hospital, Muenster, Germany

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http://dx.doi.org/10.21873/anticanres.12684DOI Listing
July 2018

Population Pharmacokinetics to Model the Time-Varying Clearance of the PEGylated Asparaginase Oncaspar in Children with Acute Lymphoblastic Leukemia.

Eur J Drug Metab Pharmacokinet 2017 12;42(6):955-963

Paediatric Haematology and Oncology, University Hospital Muenster, Albert-Schweitzer-Campus 1, Building A1, 48149, Muenster, Germany.

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http://dx.doi.org/10.1007/s13318-017-0410-5DOI Listing
December 2017

Objectively measured versus self-reported physical activity in children and adolescents with cancer.

PLoS One 2017 16;12(2):e0172216. Epub 2017 Feb 16.

Department of Pediatric Hematology and Oncology, University Children´s Hospital Münster, Münster, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0172216PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312936PMC
August 2017

Pharmacokinetic and pharmacodynamic study of doxorubicin in children with cancer: results of a "European Pediatric Oncology Off-patents Medicines Consortium" trial.

Cancer Chemother Pharmacol 2016 Dec 21;78(6):1175-1184. Epub 2016 Oct 21.

Pediatric Hematology and Oncology, University Hospital Münster, Albert-Schweitzer-Campus 1, Building A1, 48149, Münster, Germany.

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http://dx.doi.org/10.1007/s00280-016-3174-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114325PMC
December 2016

Towards a Model-Based Dose Recommendation for Doxorubicin in Children.

Clin Pharmacokinet 2017 03;56(3):215-223

Paediatric Haematology and Oncology, University Hospital Muenster, Albert-Schweitzer-Campus 1, Building A1, 48149, Münster, Germany.

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http://dx.doi.org/10.1007/s40262-016-0451-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315724PMC
March 2017

Targeting hedgehog signaling pathway in pediatric tumors: in vitro evaluation of SMO and GLI inhibitors.

Cancer Chemother Pharmacol 2016 Mar 19;77(3):495-505. Epub 2016 Jan 19.

Department of Pediatric Hematology and Oncology, University Children's Hospital Muenster, Muenster, Germany.

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http://link.springer.com/10.1007/s00280-016-2962-5
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http://dx.doi.org/10.1007/s00280-016-2962-5DOI Listing
March 2016

One in Four Questioned Children Faces Problems Regarding Reintegration Into Physical Education at School After Treatment for Pediatric Cancer.

Pediatr Blood Cancer 2016 Apr 18;63(4):737-9. Epub 2015 Dec 18.

Department of Pediatric Hematology and Oncology, University Hospital Münster, Münster, Germany.

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http://doi.wiley.com/10.1002/pbc.25852
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http://dx.doi.org/10.1002/pbc.25852DOI Listing
April 2016

Motor Performance After Treatment for Pediatric Bone Tumors.

J Pediatr Hematol Oncol 2015 Oct;37(7):509-14

*Department of Pediatric Hematology and Oncology, University Hospital Münster †Movement Analysis Laboratory, Institute for Experimental Musculoskeletal Medicine, University Hospital Münster, Muenster, Germany.

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http://dx.doi.org/10.1097/MPH.0000000000000396DOI Listing
October 2015

Age-Dependent Pharmacokinetics of Doxorubicin in Children with Cancer.

Clin Pharmacokinet 2015 Nov;54(11):1139-49

Department of Pharmaceutical and Medical Chemistry, Clinical Pharmacy, University of Muenster, Corrensstraße 48, 48149, Muenster, Germany.

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http://dx.doi.org/10.1007/s40262-015-0272-4DOI Listing
November 2015

Motor performance in children and adolescents with cancer at the end of acute treatment phase.

Eur J Pediatr 2015 Jun 28;174(6):791-9. Epub 2014 Nov 28.

Department of Pediatric Hematology and Oncology, University Hospital of Münster, Albert-Schweitzer-Campus 1, A1, 48149, Münster, Germany,

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http://dx.doi.org/10.1007/s00431-014-2460-xDOI Listing
June 2015

Reply: Should we encourage exercise and sports in children and adolescents with cancer?

Pediatr Blood Cancer 2014 Nov 17;61(11):2126. Epub 2014 Aug 17.

Department of Pediatric Hematology and Oncology, University Hospital of Münster, Münster, Germany.

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http://dx.doi.org/10.1002/pbc.25184DOI Listing
November 2014

Predictive performance of a physiologically based pharmacokinetic model of busulfan in children.

Pediatr Hematol Oncol 2014 Nov 9;31(8):731-42. Epub 2014 Jul 9.

1Department of Pharmaceutical and Medical Chemistry - Clinical Pharmacy, University of Münster, Münster, Germany.

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http://dx.doi.org/10.3109/08880018.2014.927945DOI Listing
November 2014

Population pharmacokinetics of intravenous busulfan in children: revised body weight-dependent NONMEM® model to optimize dosing.

Eur J Clin Pharmacol 2014 Jul 9;70(7):839-47. Epub 2014 May 9.

Department of Pharmaceutical and Medical Chemistry - Clinical Pharmacy, University of Münster, Corrensstr. 48, 48149, Münster, Germany.

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http://dx.doi.org/10.1007/s00228-014-1692-zDOI Listing
July 2014

Experience of barriers and motivations for physical activities and exercise during treatment of pediatric patients with cancer.

Pediatr Blood Cancer 2014 Sep 17;61(9):1632-7. Epub 2014 Apr 17.

Department of Pediatric Hematology and Oncology, University Hospital of Muenster, Muenster, Germany.

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http://dx.doi.org/10.1002/pbc.25071DOI Listing
September 2014

Sources of preanalytical error in pharmacokinetic analyses - focus on intravenous drug administration and collection of blood samples.

Expert Opin Drug Metab Toxicol 2014 Jun 16;10(6):825-38. Epub 2014 Apr 16.

University Hospital Muenster, Centre for Clinical Trials (ZKS) , Von-Esmarch-Straße 62, 48149 Muenster , Germany +49 251 83 57104 ; +49 251 57026 ;

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http://www.tandfonline.com/doi/full/10.1517/17425255.2014.90
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http://dx.doi.org/10.1517/17425255.2014.907273DOI Listing
June 2014

Sports in pediatric oncology: the role(s) of physical activity for children with cancer.

J Pediatr Hematol Oncol 2014 Mar;36(2):85-90

Department of Pediatric Hematology and Oncology, University Hospital, Münster Germany.

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http://dx.doi.org/10.1097/MPH.0000000000000101DOI Listing
March 2014

Comparison of self-reported physical activity in children and adolescents before and during cancer treatment.

Pediatr Blood Cancer 2014 Jun 19;61(6):1023-8. Epub 2013 Dec 19.

Department of Pediatric Hematology and Oncology, University Hospital of Muenster, Muenster, Germany.

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http://dx.doi.org/10.1002/pbc.24898DOI Listing
June 2014

Immediate cooling does not prevent the ex vivo hydrolysis of L-asparagine by asparaginase.

Ther Drug Monit 2014 Aug;36(4):549-52

*Department of Pediatric Hematology and Oncology, University Children's Hospital of Muenster, Muenster, Germany; and †Laboratory of Cancer Pharmacology, Department of Oncology, IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.

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http://pdfs.journals.lww.com/drug-monitoring/2014/08000/Imme
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/FTD.0000000000000030DOI Listing
August 2014

Evaluation of effects of busulfan and DMA on SOS in pediatric stem cell recipients.

Pediatr Blood Cancer 2014 Feb 30;61(2):306-11. Epub 2013 Oct 30.

Department of Pediatric Hematology and Oncology, University Childrens Hospital Münster, Muenster, Germany.

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http://doi.wiley.com/10.1002/pbc.24827
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http://dx.doi.org/10.1002/pbc.24827DOI Listing
February 2014

Physiologically based pharmacokinetic modelling of Busulfan: a new approach to describe and predict the pharmacokinetics in adults.

Cancer Chemother Pharmacol 2013 Nov 6;72(5):991-1000. Epub 2013 Sep 6.

Department of Pharmaceutical and Medical Chemistry, Clinical Pharmacy, University of Münster, Corrensstr. 48, 48149, Münster, Germany.

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http://dx.doi.org/10.1007/s00280-013-2275-xDOI Listing
November 2013

Population pharmacokinetics of dimethylacetamide in children during standard and once-daily IV busulfan administration.

Cancer Chemother Pharmacol 2013 Nov 15;72(5):1149-55. Epub 2013 Sep 15.

Department of Pharmaceutical and Medical Chemistry, Clinical Pharmacy, University of Münster, Münster, Germany,

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http://link.springer.com/10.1007/s00280-013-2284-9
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http://dx.doi.org/10.1007/s00280-013-2284-9DOI Listing
November 2013

Population pharmacokinetics of doxorubicin: establishment of a NONMEM model for adults and children older than 3 years.

Cancer Chemother Pharmacol 2013 Mar 13;71(3):749-63. Epub 2013 Jan 13.

Department of Pharmaceutical and Medical Chemistry, Clinical Pharmacy, University of Muenster, Hittorfstraße 58-62, 48149 Muenster, Germany.

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http://dx.doi.org/10.1007/s00280-013-2069-1DOI Listing
March 2013

The effect of individualized exercise interventions during treatment in pediatric patients with a malignant bone tumor.

Support Care Cancer 2013 Jun 5;21(6):1629-36. Epub 2013 Jan 5.

Institute of Experimental Musculoskeletal Medicine (IEMM) Motion Analysis Lab, University Hospital Münster, Münster, Germany.

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http://link.springer.com/10.1007/s00520-012-1707-1
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http://dx.doi.org/10.1007/s00520-012-1707-1DOI Listing
June 2013

No evidence of increased asparagine levels in the bone marrow of patients with acute lymphoblastic leukemia during asparaginase therapy.

Pediatr Blood Cancer 2013 Feb 7;60(2):258-61. Epub 2012 Sep 7.

Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/pbc.24292DOI Listing
February 2013

Population pharmacokinetics of native Escherichia coli asparaginase.

Pediatr Hematol Oncol 2012 Mar;29(2):154-65

Department of Pharmaceutical and Medical Chemistry-Clinical Pharmacy, University of Münster, Münster, Germany.

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http://dx.doi.org/10.3109/08880018.2011.627978DOI Listing
March 2012

Antineoplastic agent busulfan regulates a network of genes related to coagulation and fibrinolysis.

Eur J Clin Pharmacol 2012 Jun;68(6):923-35

Research Center of Pharmacology and Experimental Therapeutics,Department of Pharmacology, Ernst-Moritz-Arndt-Universityof Greifswald,Greifswald, Germany.

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http://dx.doi.org/10.1007/s00228-011-1209-yDOI Listing
June 2012

Minimization of the preanalytical error in plasma samples for pharmacokinetic analyses and therapeutic drug monitoring--using doxorubicin as an example.

Ther Drug Monit 2011 Dec;33(6):766-71

Department of Pharmaceutical and Medical Chemistry, Clinical Pharmacy, University of Muenster, Muenster, Germany.

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http://dx.doi.org/10.1097/FTD.0b013e31823aa8abDOI Listing
December 2011

Oral low-dose chemotherapy: successful treatment of an alveolar rhabdomyosarcoma during pregnancy.

Pediatr Blood Cancer 2012 Jan 16;58(1):104-6. Epub 2011 Jan 16.

Clinic of Pediatric Hematology, Oncology and Clinical Immunology, Heinrich Heine University, Duesseldorf, Germany.

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http://dx.doi.org/10.1002/pbc.22934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138827PMC
January 2012

Population pharmacokinetics of busulfan in children: increased evidence for body surface area and allometric body weight dosing of busulfan in children.

Clin Cancer Res 2011 Nov 14;17(21):6867-77. Epub 2011 Sep 14.

Department of Pharmaceutical and Medical Chemistry-Clinical Pharmacy, Westfälische Wilhelms-Universität Münster, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-0074DOI Listing
November 2011

Drug delivery and formulations.

Handb Exp Pharmacol 2011 ;205:91-107

Institut für Pharmazeutische Technologie und Biopharmazie, Heinrich-Heine-Universität Düsseldorf, Universitätsstraße 1, 40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1007/978-3-642-20195-0_4DOI Listing
February 2012

Physiologically based pharmacokinetic modelling of high- and low-dose etoposide: from adults to children.

Cancer Chemother Pharmacol 2012 Feb 26;69(2):397-405. Epub 2011 Jul 26.

Department of Pharmaceutical and Medical Chemistry, Clinical Pharmacy, University of Münster, Münster, Germany.

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http://dx.doi.org/10.1007/s00280-011-1706-9DOI Listing
February 2012

An in-vitro evaluation of the polo-like kinase inhibitor GW843682X against paediatric malignancies.

Anticancer Drugs 2011 Jul;22(6):531-42

Department of Paediatric Haematology and Oncology, University Children's Hospital, Muenster, Germany.

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http://dx.doi.org/10.1097/CAD.0b013e3283454526DOI Listing
July 2011

Methodological and ethical aspects of randomized controlled clinical trials in minors with malignant diseases.

Pediatr Blood Cancer 2011 Oct 5;57(4):599-605. Epub 2011 May 5.

Department of Pediatric Hematology and Oncology, University Children's Hospital, Muenster, Germany.

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http://dx.doi.org/10.1002/pbc.23171DOI Listing
October 2011

Carboplatin dosing in children: calculation by different formulae.

Onkologie 2011 17;34(1-2):16-22. Epub 2011 Jan 17.

Zentrum für Klinische Studien, Universitätsklinikum Münster, Germany.

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http://dx.doi.org/10.1159/000323369DOI Listing
July 2011

Five-year single-center study of asparaginase therapy within the ALL-BFM 2000 trial.

Pediatr Blood Cancer 2011 Sep 18;57(3):378-84. Epub 2011 Feb 18.

Department of Paediatric Haematology and Oncology, University Hospital Muenster, Muenster, Germany.

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http://dx.doi.org/10.1002/pbc.23041DOI Listing
September 2011

Pediatric patients with a malignant bone tumor: when does functional assessment make sense?

Support Care Cancer 2012 Jan 20;20(1):127-33. Epub 2011 Jan 20.

Department of Orthopedic Surgery, University Hospital Münster, Albert-Schweitzer-Str. 33, 48149, Münster, Germany.

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http://dx.doi.org/10.1007/s00520-010-1077-5DOI Listing
January 2012

Early decrements in bone density after completion of neoadjuvant chemotherapy in pediatric bone sarcoma patients.

BMC Musculoskelet Disord 2010 Dec 29;11:287. Epub 2010 Dec 29.

Motion Analysis Lab, Department of General Orthopedics and Tumororthopedics, University Hospital Münster, Domagkstr, 3, 48149 Münster, Germany.

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http://dx.doi.org/10.1186/1471-2474-11-287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022904PMC
December 2010

Therapeutic drug monitoring of methotrexate in cerebrospinal fluid after systemic high-dose infusion in children: can the burden of intrathecal methotrexate be reduced?

Ther Drug Monit 2010 Aug;32(4):467-75

Department of Pediatric Hematology and Oncology, University Children's Hospital, Münster, Germany.

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http://dx.doi.org/10.1097/FTD.0b013e3181e5c6b3DOI Listing
August 2010

Dichloroacetate metabolically targeted therapy defeats cytotoxicity of standard anticancer drugs.

Cancer Chemother Pharmacol 2011 Mar 26;67(3):647-55. Epub 2010 May 26.

Department of Paediatric Haematology and Oncology, University Children's Hospital, Muenster, Germany.

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http://dx.doi.org/10.1007/s00280-010-1361-6DOI Listing
March 2011

The role of the 'innovative therapies for children with cancer' (ITCC) European consortium.

Cancer Treat Rev 2010 Jun 15;36(4):328-34. Epub 2010 Mar 15.

Dept. of Ped Oncology/Hematology, Erasmus MC/Sophia Children's Hospital, GJ Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ctrv.2010.02.008DOI Listing
June 2010

High Frequency of p53/MDM2/p14ARF Pathway Abnormalities in Relapsed Neuroblastoma.

Clin Cancer Res 2010 Feb 9;16(4):1108-18. Epub 2010 Feb 9.

Department of Cellular Pathology, Northern Institute for Cancer Research, Royal Victoria Infirmary, Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-1865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842933PMC
February 2010

Therapeutic drug monitoring of asparaginase in the ALL-BFM 2000 protocol between 2000 and 2007.

Pediatr Blood Cancer 2010 Jul;54(7):952-8

Department of Paediatric Haematology and Oncology, University Hospital Muenster, Muenster, Germany.

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http://dx.doi.org/10.1002/pbc.22417DOI Listing
July 2010

A population pharmacokinetic model for pegylated-asparaginase in children.

Br J Haematol 2010 Jan 11;148(1):119-25. Epub 2009 Oct 11.

Institut für Pharmazeutische und Medizinische Chemie - Klinische Pharmazie-, Westfälische Wilhelms-Universität Münster, Germany.

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http://dx.doi.org/10.1111/j.1365-2141.2009.07923.xDOI Listing
January 2010

Physical activity and childhood cancer.

Pediatr Blood Cancer 2010 Apr;54(4):501-10

Movement Analysis Lab, Orthopedic Department, University Hospital Muenster, Muenster, Germany.

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http://dx.doi.org/10.1002/pbc.22271DOI Listing
April 2010

Pharmacokinetics of daunorubicin and daunorubicinol in infants with leukemia treated in the interfant 99 protocol.

Pediatr Blood Cancer 2010 Mar;54(3):355-60

Institut für Pharmazeutische und Medizinische Chemie, Klinische Pharmazie, Münster, Germany.

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http://doi.wiley.com/10.1002/pbc.22266
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http://dx.doi.org/10.1002/pbc.22266DOI Listing
March 2010

Level of activity in children undergoing cancer treatment.

Pediatr Blood Cancer 2009 Sep;53(3):438-43

Motion Analysis Laboratory, University Hospital Muenster, Muenster, Germany.

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http://dx.doi.org/10.1002/pbc.22055DOI Listing
September 2009

Flat-fixed dosing versus body surface area based dosing of anticancer drugs: there is a difference.

Oncologist 2007 Aug;12(8):924-6

Institut für Pharmazeutische und Medizinische Chemie -Klinische Pharmazie-Hittorfstr. 58-62, 48149 Münster, Germany.

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http://theoncologist.alphamedpress.org/cgi/doi/10.1634/theon
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http://dx.doi.org/10.1634/theoncologist.12-8-924DOI Listing
August 2007

Cytotoxicity of dimethylacetamide and pharmacokinetics in children receiving intravenous busulfan.

J Clin Oncol 2007 May;25(13):1772-8

Klinik und Poliklinik für Kinder und Jugendmedizin, Pädiatrische Hämatologie/Onkologie, Münster, Germany.

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http://dx.doi.org/10.1200/JCO.2006.08.8807DOI Listing
May 2007

Comment on "determination of treosulfan in plasma and urine by HPLC with refractometric detection; pharmacokinetic studies in children undergoing myeloablative treatment prior to haematopoietic stem cell transplantation" by F.K. Glowka et al. [J. Chromatogr. B 850 (2007) 569-574].

J Chromatogr B Analyt Technol Biomed Life Sci 2007 Jun 24;853(1-2):369-70; discussion 371. Epub 2007 Mar 24.

University of Münster, Institute of Pharmaceutical and Medicinal Chemistry, and Department of Paediatric Haematology and Oncology, Universith Children's Hospital, Münster, Germany.

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http://dx.doi.org/10.1016/j.jchromb.2007.02.060DOI Listing
June 2007

Implementing Good Clinical Practice in two noncommercial phase II studies in children with cancer.

Onkologie 2007 Feb 26;30(1-2):21-6. Epub 2007 Jan 26.

Coordinating Centre for Clinical Trials, University Hospital of Münster, Germany.

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http://dx.doi.org/10.1159/000098424DOI Listing
February 2007

Paediatric and geriatric drug delivery.

Expert Opin Drug Deliv 2007 Jan;4(1):37-45

Heinrich-Heine-University Düsseldorf, Institute of Pharmaceutics and Biopharmaceutics Universitätsstrasse 1, 40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1517/17425247.4.1.37DOI Listing
January 2007

In-vitro toxicity of Ukrain against human Ewing tumor cell lines.

Anticancer Drugs 2006 Oct;17(9):1025-30

Department of Pediatric Hematology and Oncology, University Children's Hospital, Münster, Germany.

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http://dx.doi.org/10.1097/01.cad.0000231467.61911.50DOI Listing
October 2006

Cytotoxicity of treosulfan and busulfan on pediatric tumor cell lines.

Anticancer Drugs 2006 Jul;17(6):657-62

Department of Pediatric Hematology and Oncology, University Children's Hospital, Münster, Germany.

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http://dx.doi.org/10.1097/01.cad.0000215059.93437.89DOI Listing
July 2006

Monitoring of N,N-dimethylacetamide in children during i.v.-busulfan therapy by liquid chromatography-mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci 2006 Jul 24;838(2):129-34. Epub 2006 May 24.

Klinik und Poliklinik für Kinder- und Jugendmedizin, Pädiatrische Hämatologie/Onkologie, Albert-Schweitzer-Str. 33, 48129 Muenster, Germany.

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http://dx.doi.org/10.1016/j.jchromb.2006.04.034DOI Listing
July 2006

Interactions of carboxypeptidase G2 with 6S-leucovorin and 6R-leucovorin in vitro: implications for the application in case of methotrexate intoxications.

Cancer Chemother Pharmacol 2005 Apr 21;55(4):347-353. Epub 2004 Oct 21.

Pädiatrische Hämatologie und Onkologie, Klinik und Poliklinik für Kinder- und Jugendmedizin, Munster, Germany.

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http://dx.doi.org/10.1007/s00280-004-0910-2DOI Listing
April 2005

Toxicity and pharmacokinetics of i.v. busulfan in children before stem cell transplantation.

Anticancer Drugs 2005 Mar;16(3):337-44

Universitätsklinikum Münster, Klinik und Poliklinik für Kinderheilkunde, Pädiatrische Hämatologie/Onkologie, Münster, Germany.

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http://dx.doi.org/10.1097/00001813-200503000-00014DOI Listing
March 2005

Pharmacokinetics of intravenous paracetamol in children and adolescents under major surgery.

Eur J Clin Pharmacol 2005 Feb 21;60(12):883-8. Epub 2005 Jan 21.

Coordinating Centre for Clinical Trials (KKS), University Hospital Muenster, Muenster, Germany.

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http://dx.doi.org/10.1007/s00228-004-0873-6DOI Listing
February 2005

Cytotoxic effects of novel polyoxotungstates and a platinum compound on human cancer cell lines.

Anticancer Drugs 2005 Jan;16(1):101-6

Institute of Inorganic and Analytical Chemistry, Westphalian Wilhelms-University, Muenster, Germany.

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http://dx.doi.org/10.1097/00001813-200501000-00015DOI Listing
January 2005

In vitro toxicity of bisphosphonates on human neuroblastoma cell lines.

Anticancer Drugs 2004 Sep;15(8):795-802

University Children's Hospital, Department of Pediatric Hematology and Oncology, Münster, Germany.

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http://dx.doi.org/10.1097/00001813-200409000-00009DOI Listing
September 2004

The best way to use asparaginase in childhood acute lymphatic leukaemia--still to be defined?

Br J Haematol 2004 Apr;125(2):117-27

Coordination Centre for Clinical Trials (KKS), University Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.1111/j.1365-2141.2004.04863.xDOI Listing
April 2004

The bisphosphonate pamidronate is a potent inhibitor of Ewing's sarcoma cell growth in vitro.

Anticancer Drugs 2003 Oct;14(9):767-71

Labor für Experimentelle Orthopädie/Zellbiologie, Klinik und Poliklinik für Allgemeine Orthopädie, Universitätsklinikum Münster, Germany.

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http://dx.doi.org/10.1097/00001813-200310000-00013DOI Listing
October 2003

Population pharmacokinetics of liposomal daunorubicin in children.

Br J Clin Pharmacol 2003 Oct;56(4):370-7

Institut für Pharmazeutische und Medizinische Chemie, Westfälische Wilhelms-Universität, Hittorfstrasse 58-62, 48149 Münster, Germany.

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http://dx.doi.org/10.1046/j.1365-2125.2003.01886.xDOI Listing
October 2003

Population pharmacokinetics of low-dose paclitaxel in patients with brain tumors.

Anticancer Drugs 2003 Jul;14(6):417-22

Klinik und Poliklinik für Kinderheilkunde (Pädiatrische Hämatologie/Onkologie), Münster, Germany.

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http://dx.doi.org/10.1097/00001813-200307000-00005DOI Listing
July 2003

Population pharmacokinetics of oral busulfan in children.

Cancer Chemother Pharmacol 2003 Sep 17;52(3):209-16. Epub 2003 Jun 17.

Pädiatrische Hämatologie/Onkologie, Klinik und Poliklinik für Kinderheilkunde, Universitätsklinikum Münster, Albert-Schweitzer-Strasse 33, 48129 Münster, Germany.

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http://link.springer.com/10.1007/s00280-003-0631-y
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http://dx.doi.org/10.1007/s00280-003-0631-yDOI Listing
September 2003

Pharmacology of all-trans-retinoic acid in children with acute promyelocytic leukemia.

Med Pediatr Oncol 2003 May;40(5):293-301

University Children's Hospital Muenster, Department of Pediatric Hematology and Oncology, Albert-Schweitzer-Str. 33, Germany.

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http://dx.doi.org/10.1002/mpo.10257DOI Listing
May 2003

Determination of free and liposome-associated daunorubicin and daunorubicinol in plasma by capillary electrophoresis.

J Chromatogr A 2002 Dec;979(1-2):379-88

Klinik und Poliklinik für Kinderheilkunde, Pädiatrische Hämatologie/Onkologie, Universität Münster, Albert-Schweitzer-Strasse 33, 48149 Münster, Germany.

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http://dx.doi.org/10.1016/s0021-9673(02)01440-1DOI Listing
December 2002

Analytical validation of a microplate reader-based method for the therapeutic drug monitoring of L-asparaginase in human serum.

Anal Biochem 2002 Oct;309(1):117-26

Department of Pediatric Hematology and Oncology, University Children's Hospital Muenster, Albert-Schweitzer-Str. 33, 48149 Muenster, Germany.

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http://dx.doi.org/10.1016/s0003-2697(02)00232-4DOI Listing
October 2002

On the origin of EEG-slowing and encephalopathy during induction treatment of acute lymphoblastic leukemia.

Med Pediatr Oncol 2002 Dec;39(6):566-72

Department of Neuropediatrics and Muscular Disorders, Pediatric University Hospital Freiburg, Mathildenstrasse, D-79106 Freiburg, Germany.

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http://dx.doi.org/10.1002/mpo.10189DOI Listing
December 2002

c-KIT-expressing Ewing tumour cells are insensitive to imatinib mesylate (STI571).

Cancer Chemother Pharmacol 2002 Aug 15;50(2):167-9. Epub 2002 Jun 15.

University Children's Hospital Muenster, Department of Pediatric Hematology and Oncology, University of Muenster, Albert-Schweitzer-Str. 33, 48129 Muenster, Germany.

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http://dx.doi.org/10.1007/s00280-002-0477-8DOI Listing
August 2002

Low dose--high dose: what is the right dose? Pharmacokinetic modeling of etoposide.

Cancer Chemother Pharmacol 2002 Apr 30;49(4):303-8. Epub 2002 Jan 30.

University Hospital Münster, Department of Pediatric Hematology and Oncology, 48129 Münster, Germany.

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http://dx.doi.org/10.1007/s00280-001-0418-yDOI Listing
April 2002

Population pharmacokinetics of high-dose etoposide in children receiving different conditioning regimens.

Anticancer Drugs 2002 Jan;13(1):101-10

Department of Pediatric Hematology and Oncology, University Hospital Münster, 48129 Münster, Germany.

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http://dx.doi.org/10.1097/00001813-200201000-00012DOI Listing
January 2002

Peak plasma concentrations of doxorubicin in children with acute lymphoblastic leukemia or non-Hodgkin lymphoma.

Cancer Chemother Pharmacol 2002 Feb 30;49(2):133-41. Epub 2001 Nov 30.

Institut für Pharmazeutische Chemie, Westfälische Wilhems-Universität, Münster, Germany.

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http://link.springer.com/10.1007/s00280-001-0392-4
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http://dx.doi.org/10.1007/s00280-001-0392-4DOI Listing
February 2002