Jiucun Wang

Jiucun Wang

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Jiucun Wang

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MiR-3606-3p inhibits systemic sclerosis through targeting TGF-β type II receptor.

Cell Cycle 2018 17;17(16):1967-1978. Epub 2018 Sep 17.

a State Key Laboratory of Genetic Engineering, Department of Anthropology and Human Genetics , School of Life Sciences, Fudan University , Shanghai , P. R. China.

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http://dx.doi.org/10.1080/15384101.2018.1509621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224271PMC
December 2019

Increased expression of GAB1 promotes inflammation and fibrosis in systemic sclerosis.

Exp Dermatol 2019 Nov;28(11):1313-1320

Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1111/exd.14033DOI Listing
November 2019

A rare variant of RNF123 in familial ankylosing spondylitis causes dysfunction of osteoclast formation.

Rheumatology (Oxford) 2019 Nov 7. Epub 2019 Nov 7.

State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Shanghai, China.

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http://dx.doi.org/10.1093/rheumatology/kez537DOI Listing
November 2019

Contribution of Mitochondrial DNA Variation to Chronic Disease in East Asian Populations.

Front Mol Biosci 2019 15;6:128. Epub 2019 Nov 15.

State Key Laboratory of Genetic Engineering and Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.3389/fmolb.2019.00128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873657PMC
November 2019

Molecular genealogy of Tusi Lu's family reveals their paternal relationship with Jochi, Genghis Khan's eldest son.

J Hum Genet 2019 Aug 5;64(8):815-820. Epub 2019 Jun 5.

MOE Key Laboratory of Contemporary Anthropology and B&R International Joint Laboratory for Eurasian Anthropology, School of Life Sciences, Fudan University, 200438, Shanghai, China.

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http://dx.doi.org/10.1038/s10038-019-0618-0DOI Listing
August 2019

Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women.

Authors:
Jason Y Y Wong Han Zhang Chao A Hsiung Kouya Shiraishi Kai Yu Keitaro Matsuo Maria Pik Wong Yun-Chul Hong Jiucun Wang Wei Jie Seow Zhaoming Wang Minsun Song Hee Nam Kim I-Shou Chang Nilanjan Chatterjee Wei Hu Chen Wu Tetsuya Mitsudomi Wei Zheng Jin Hee Kim Adeline Seow Neil E Caporaso Min-Ho Shin Lap Ping Chung She-Juan An Ping Wang Yang Yang Hong Zheng Yasushi Yatabe Xu-Chao Zhang Young Tae Kim Qiuyin Cai Zhihua Yin Young-Chul Kim Bryan A Bassig Jiang Chang James Chung Man Ho Bu-Tian Ji Yataro Daigo Hidemi Ito Yukihide Momozawa Kyota Ashikawa Yoichiro Kamatani Takayuki Honda H Dean Hosgood Hiromi Sakamoto Hideo Kunitoh Koji Tsuta Shun-Ichi Watanabe Michiaki Kubo Yohei Miyagi Haruhiko Nakayama Shingo Matsumoto Masahiro Tsuboi Koichi Goto Jianxin Shi Lei Song Xing Hua Atsushi Takahashi Akiteru Goto Yoshihiro Minamiya Kimihiro Shimizu Kazumi Tanaka Fusheng Wei Fumihiko Matsuda Jian Su Yeul Hong Kim In-Jae Oh Fengju Song Wu-Chou Su Yu-Min Chen Gee-Chen Chang Kuan-Yu Chen Ming-Shyan Huang Li-Hsin Chien Yong-Bing Xiang Jae Yong Park Sun-Seog Kweon Chien-Jen Chen Kyoung-Mu Lee Batel Blechter Haixin Li Yu-Tang Gao Biyun Qian Daru Lu Jianjun Liu Hyo-Sung Jeon Chin-Fu Hsiao Jae Sook Sung Ying-Huang Tsai Yoo Jin Jung Huan Guo Zhibin Hu Wen-Chang Wang Charles C Chung Laurie Burdett Meredith Yeager Amy Hutchinson Sonja I Berndt Wei Wu Herbert Pang Yuqing Li Jin Eun Choi Kyong Hwa Park Sook Whan Sung Li Liu C H Kang Meng Zhu Chung-Hsing Chen Tsung-Ying Yang Jun Xu Peng Guan Wen Tan Chih-Liang Wang Michael Hsin Ko-Yung Sit James Ho Ying Chen Yi Young Choi Jen-Yu Hung Jun Suk Kim Ho Il Yoon Chien-Chung Lin In Kyu Park Ping Xu Yuzhuo Wang Qincheng He Reury-Perng Perng Chih-Yi Chen Roel Vermeulen Junjie Wu Wei-Yen Lim Kun-Chieh Chen Yao-Jen Li Jihua Li Hongyan Chen Chong-Jen Yu Li Jin Tzu-Yu Chen Shih-Sheng Jiang Jie Liu Taiki Yamaji Belynda Hicks Kathleen Wyatt Shengchao A Li Juncheng Dai Hongxia Ma Guangfu Jin Bao Song Zhehai Wang Sensen Cheng Xuelian Li Yangwu Ren Ping Cui Motoki Iwasaki Taichi Shimazu Shoichiro Tsugane Junjie Zhu Ying Chen Kaiyun Yang Gening Jiang Ke Fei Guoping Wu Hsien-Chin Lin Hui-Ling Chen Yao-Huei Fang Fang-Yu Tsai Wan-Shan Hsieh Jinming Yu Victoria L Stevens Ite A Laird-Offringa Crystal N Marconett Linda Rieswijk Ann Chao Pan-Chyr Yang Xiao-Ou Shu Tangchun Wu Y L Wu Dongxin Lin Kexin Chen Baosen Zhou Yun-Chao Huang Takashi Kohno Hongbing Shen Stephen J Chanock Nathaniel Rothman Qing Lan

Genomics 2019 Jul 12. Epub 2019 Jul 12.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.ygeno.2019.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954985PMC
July 2019

MICA*049, not MICA*009, is associated with Behçet's disease in a Chinese population.

Sci Rep 2019 Jul 26;9(1):10856. Epub 2019 Jul 26.

Department of Internal Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA.

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http://dx.doi.org/10.1038/s41598-019-47289-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659628PMC
July 2019

Genetic association of non-MHC region with ankylosing spondylitis in a Chinese population.

Ann Rheum Dis 2019 06 14;78(6):852-853. Epub 2018 Dec 14.

State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China

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http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2018-21462
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http://dx.doi.org/10.1136/annrheumdis-2018-214625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579548PMC
June 2019

IgG Galactosylation status combined with MYOM2-rs2294066 precisely predicts anti-TNF response in ankylosing spondylitis.

Mol Med 2019 Jun 13;25(1):25. Epub 2019 Jun 13.

State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1186/s10020-019-0093-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567531PMC
June 2019

Genome-Wide DNA Methylation Profiles Reveal Common Epigenetic Patterns of Interferon-Related Genes in Multiple Autoimmune Diseases.

Front Genet 2019 5;10:223. Epub 2019 Apr 5.

State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.3389/fgene.2019.00223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459983PMC
April 2019

[Expression of calponin-1 and its pathogenic role in systemic sclerosis].

Nan Fang Yi Ke Da Xue Xue Bao 2019 Mar;39(3):279-285

School of Life Sciences, Fudan University, Shanghai 200433, China.

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http://dx.doi.org/10.12122/j.issn.1673-4254.2019.03.04DOI Listing
March 2019

Polymorphism rs3819102 in thymidylate synthase and environmental factors: effects on lung cancer in Chinese population.

Curr Probl Cancer 2019 02 21;43(1):66-74. Epub 2018 Jul 21.

Department of Respiratory and Critical Care Medicine, Navy Military Medical University Affiliated Changhai Hospital, Shanghai, China; State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.currproblcancer.2018.07.005DOI Listing
February 2019

Associations of Multiple Exonic Variants with Systemic Sclerosis.

J Rheumatol 2019 02 15;46(2):184-189. Epub 2018 Nov 15.

From the Division of Rheumatology, Department of Internal Medicine, University of Texas McGovern Medical School; Human Genetics Center, Division of Biostatistics, The University of Texas School of Public Health, Houston, Texas, USA; State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai; Department of Rheumatology, Jiangxi People's Hospital, Nanchang; Department of Rheumatology, Peking University-Shenzhen Hospital, Shenzhen; Life Sciences College, Hubei University, Wuhan, China.

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http://www.jrheum.org/lookup/doi/10.3899/jrheum.180094
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http://dx.doi.org/10.3899/jrheum.180094DOI Listing
February 2019

Salvianolic acid B attenuates experimental skin fibrosis of systemic sclerosis.

Biomed Pharmacother 2019 Feb 7;110:546-553. Epub 2018 Dec 7.

Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China; Institute of Rheumatology, Immunology and Allergy, Fudan University, Shanghai, China; Department of dermatology, Jing'an District Central Hospital, Shanghai, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07533322183766
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http://dx.doi.org/10.1016/j.biopha.2018.12.016DOI Listing
February 2019

HLA class I and II alleles in susceptibility to ankylosing spondylitis.

Ann Rheum Dis 2019 01 19;78(1):66-73. Epub 2018 Oct 19.

Institute of Health and Biomedical Innovation, Queensland University of Technology, Translational Research Institute, Princess Alexandra Hospital, Brisbane, Queensland, Australia.

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http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2018-21377
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http://dx.doi.org/10.1136/annrheumdis-2018-213779DOI Listing
January 2019

Salvianolic acid B attenuates experimental pulmonary inflammation by protecting endothelial cells against oxidative stress injury.

Eur J Pharmacol 2018 Dec 28;840:9-19. Epub 2018 Sep 28.

Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China; Department of Dermatology, Jing'an District Central Hospital, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2018.09.030DOI Listing
December 2018

Bandgap Engineered Polypyrrole-Polydopamine Hybrid with Intrinsic Raman and Photoacoustic Imaging Contrasts.

Nano Lett 2018 12 26;18(12):7485-7493. Epub 2018 Nov 26.

Jiangsu Collaborative Innovation Center of Biomedical Functional Materials , Nanjing Normal University , Nanjing 210046 , China.

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http://dx.doi.org/10.1021/acs.nanolett.8b02901DOI Listing
December 2018

Evaluation of the antifibrotic potency by knocking down SPARC, CCR2 and SMAD3.

EBioMedicine 2018 Dec 20;38:238-247. Epub 2018 Nov 20.

University of Texas-McGovern Medical School, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.11.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306344PMC
December 2018

Anti-SIRT1 autoantibody is elevated in ankylosing spondylitis: a potential disease biomarker.

BMC Immunol 2018 12 17;19(1):38. Epub 2018 Dec 17.

Department of Rheumatology and Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Second Road, Shanghai, 200025, China.

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https://bmcimmunol.biomedcentral.com/articles/10.1186/s12865
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http://dx.doi.org/10.1186/s12865-018-0280-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298004PMC
December 2018

All-Trans Retinoic Acid Induces CD4+CD25+FOXP3+ Regulatory T Cells by Increasing FOXP3 Demethylation in Systemic Sclerosis CD4+ T Cells.

J Immunol Res 2018 30;2018:8658156. Epub 2018 Apr 30.

Department of Dermatology, Second Xiangya Hospital, Central South University, 139 Ren-Min Road, Changsha 410011, China.

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http://dx.doi.org/10.1155/2018/8658156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952589PMC
October 2018

Combination of 5-aminolevulinic acid and iron prevents skin fibrosis in murine sclerodermatous graft-versus-host disease.

Exp Dermatol 2018 10 20;27(10):1104-1111. Epub 2018 Aug 20.

Division of Transplantation Immunology, National Research Institute for Child Health and Development, Tokyo, Japan.

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http://dx.doi.org/10.1111/exd.13730DOI Listing
October 2018

Physiological, hematological and biochemical factors associated with high-altitude headache in young Chinese males following acute exposure at 3700 m.

J Headache Pain 2018 Jul 25;19(1):59. Epub 2018 Jul 25.

State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, 200438, China.

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http://dx.doi.org/10.1186/s10194-018-0878-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060196PMC
July 2018

Hypoxic-stabilized EPAS1 proteins transactivate DNMT1 and cause promoter hypermethylation and transcription inhibition of EPAS1 in non-small cell lung cancer.

FASEB J 2018 Jun 19:fj201700715. Epub 2018 Jun 19.

State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1096/fj.201700715DOI Listing
June 2018

Risk factors of age-related cataract in a Chinese adult population: the Taizhou Eye Study.

Clin Exp Ophthalmol 2018 05 28;46(4):371-379. Epub 2017 Sep 28.

Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China.

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http://dx.doi.org/10.1111/ceo.13040DOI Listing
May 2018

Genome-Wide DNA Methylation Analysis in Systemic Sclerosis Reveals Hypomethylation of IFN-Associated Genes in CD4 and CD8 T Cells.

J Invest Dermatol 2018 05 15;138(5):1069-1077. Epub 2017 Dec 15.

State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China; Institute of Rheumatology, Immunology and Allergy, Fudan University, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2017.12.003DOI Listing
May 2018

Genetic polymorphism of is associated with clinical outcomes of platinum-based chemotherapy in non-small-cell lung cancer patients through modulating microRNA-mediated regulation.

Oncotarget 2018 May 8;9(35):23860-23877. Epub 2018 May 8.

State Key Laboratory of Genetic Engineering and Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.18632/oncotarget.24794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963629PMC
May 2018

Genetic variants in two pathways influence serum urate levels and gout risk: a systematic pathway analysis.

Sci Rep 2018 03 1;8(1):3848. Epub 2018 Mar 1.

State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University Jiangwan Campus, Shanghai, China.

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http://dx.doi.org/10.1038/s41598-018-21858-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832812PMC
March 2018

A standardized fold change method for microarray differential expression analysis used to reveal genes involved in acute rejection in murine allograft models.

FEBS Open Bio 2018 03 25;8(3):481-490. Epub 2018 Jan 25.

State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology Collaborative Innovation Center for Genetics and Development School of Life Sciences and Institutes of Biomedical Sciences Fudan University Shanghai China.

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http://dx.doi.org/10.1002/2211-5463.12343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832988PMC
March 2018

S100A9 aggravates bleomycin-induced dermal fibrosis in mice via activation of ERK1/2 MAPK and NF-κB pathways.

Iran J Basic Med Sci 2018 Feb;21(2):194-201

Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, Jiangsu, China.

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http://dx.doi.org/10.22038/IJBMS.2018.19987.5255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811759PMC
February 2018

Sirtuin1 Protects against Systemic Sclerosis-related Pulmonary Fibrosis by Decreasing Proinflammatory and Profibrotic Processes.

Am J Respir Cell Mol Biol 2018 01;58(1):28-39

1 State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences.

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http://dx.doi.org/10.1165/rcmb.2016-0192OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941307PMC
January 2018

Delayed-onset of progressive pseudorheumatoid dysplasia in a Chinese adult with a novel compound WISP3 mutation: a case report.

BMC Med Genet 2017 12 15;18(1):149. Epub 2017 Dec 15.

Department of Rheumatology and Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.

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http://dx.doi.org/10.1186/s12881-017-0507-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732398PMC
December 2017

Predictive model for inflammation grades of chronic hepatitis B: Large-scale analysis of clinical parameters and gene expressions.

Liver Int 2017 11 19;37(11):1632-1641. Epub 2017 Apr 19.

Department of Digestive Diseases of Huashan Hospital, Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1111/liv.13427DOI Listing
November 2017

Mendelian randomization analysis indicates serum urate has a causal effect on renal function in Chinese women.

Int Urol Nephrol 2017 Nov 30;49(11):2035-2042. Epub 2017 Aug 30.

State Key Laboratory of Genetic Engineering and Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, 2005, Songhu Road, Shanghai, China.

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http://dx.doi.org/10.1007/s11255-017-1686-8DOI Listing
November 2017

Hdac7 promotes lung tumorigenesis by inhibiting Stat3 activation.

Mol Cancer 2017 Nov 10;16(1):170. Epub 2017 Nov 10.

Obstetrics & Gynecology Hospital and State Key Laboratory of Genetic Engineering and Institute of Developmental Biology and Molecular Medicine, Collaborative Innovation Center of Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1186/s12943-017-0736-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681774PMC
November 2017

Elevated serum urate is a potential factor in reduction of total bilirubin: a Mendelian randomization study.

Oncotarget 2017 Nov 24;8(61):103864-103873. Epub 2017 Oct 24.

State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.18632/oncotarget.21977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732772PMC
November 2017

Bagging Nearest-Neighbor Prediction independence Test: an efficient method for nonlinear dependence of two continuous variables.

Sci Rep 2017 10 6;7(1):12736. Epub 2017 Oct 6.

State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1038/s41598-017-12783-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630623PMC
October 2017

DHX15 is associated with poor prognosis in acute myeloid leukemia (AML) and regulates cell apoptosis via the NF-kB signaling pathway.

Oncotarget 2017 Oct 16;8(52):89643-89654. Epub 2017 Aug 16.

Fujian Institute of Hematology, Fujian Provincial Key Laboratory on Hematology, Department of Hematology, Fujian Medical University Union Hospital, Fuzhou, PR China.

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http://dx.doi.org/10.18632/oncotarget.20288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685698PMC
October 2017

Single nucleotide polymorphisms of nucleotide excision repair pathway are significantly associated with outcomes of platinum-based chemotherapy in lung cancer.

Sci Rep 2017 09 18;7(1):11785. Epub 2017 Sep 18.

State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1038/s41598-017-08257-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603542PMC
September 2017

Sirt1 ameliorates systemic sclerosis by targeting the mTOR pathway.

J Dermatol Sci 2017 Aug 3;87(2):149-158. Epub 2017 May 3.

Division of Rheumatology, Huashan Hospital, Fudan University, China; Institute of Rheumatology, Immunology and Allergy, Fudan University, China. Electronic address:

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http://dx.doi.org/10.1016/j.jdermsci.2017.04.013DOI Listing
August 2017

Clinical patterns and characteristics of ankylosing spondylitis in China.

Clin Rheumatol 2017 Jul 27;36(7):1561-1568. Epub 2017 May 27.

State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1007/s10067-017-3660-3DOI Listing
July 2017

Copy number variants of ABCF1, IL17REL, and FCGR3A are associated with the risk of gout.

Protein Cell 2017 06;8(6):467-470

State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, 200433, China.

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http://dx.doi.org/10.1007/s13238-017-0401-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445030PMC
June 2017

Genome-wide screening for highly discriminative SNPs for personal identification and their assessment in world populations.

Forensic Sci Int Genet 2017 05 16;28:118-127. Epub 2017 Feb 16.

MOE Key Laboratory of Contemporary Anthropology and State Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Developmental Biology and School of Life Sciences, Fudan University, Shanghai, 200438, China; Fudan-Taizhou Institute of Health Sciences, Jiangsu, 225300, China. Electronic address:

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http://dx.doi.org/10.1016/j.fsigen.2017.02.005DOI Listing
May 2017

Treatment effects of the traditional Chinese medicine Shenks in bleomycin-induced lung fibrosis through regulation of TGF-beta/Smad3 signaling and oxidative stress.

Sci Rep 2017 05 22;7(1):2252. Epub 2017 May 22.

State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, 2005 Songhu Road, Shanghai, 200438, P. R. China.

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http://dx.doi.org/10.1038/s41598-017-02293-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440393PMC
May 2017

Polymorphisms in nucleotide excision repair genes and risk of primary prostate cancer in Chinese Han populations.

Oncotarget 2017 Apr;8(15):24362-24371

Cancer Institute, Collaborative Innovation Center for Cancer Medicine, Fudan University Shanghai Cancer Center, Shanghai, China.

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http://dx.doi.org/10.18632/oncotarget.13848DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421853PMC
April 2017

A single nucleotide variant in microRNA-1269a promotes the occurrence and process of hepatocellular carcinoma by targeting to oncogenes SPATS2L and LRP6.

Bull Cancer 2017 Apr 9;104(4):311-320. Epub 2017 Jan 9.

Xiamen University, Southeast Hospital, Department of Digestive Diseases, Zhangzhou, Fujian, China. Electronic address:

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http://dx.doi.org/10.1016/j.bulcan.2016.11.021DOI Listing
April 2017

Is there a dose-dependent effect of genetic susceptibility loci for gastric cancer on prognosis of the patients?

Oncotarget 2017 Mar;8(11):18435-18443

Cancer Institute, Collaborative Innovation Center for Cancer Medicine, Fudan University Shanghai Cancer Center, Xuhui, Shanghai, China.

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http://dx.doi.org/10.18632/oncotarget.13123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392341PMC
March 2017

Effects of multiple genetic loci on the pathogenesis from serum urate to gout.

Sci Rep 2017 03 2;7:43614. Epub 2017 Mar 2.

State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University Jiangwan Campus, Shanghai, China.

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http://dx.doi.org/10.1038/srep43614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333621PMC
March 2017

Genetic variants of JNK and p38α pathways and risk of non-small cell lung cancer in an Eastern Chinese population.

Int J Cancer 2017 02 16;140(4):807-817. Epub 2016 Nov 16.

Cancer Institute, Collaborative Innovation Center for Cancer Medicine, Fudan University Shanghai Cancer Center, Shanghai, China.

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http://dx.doi.org/10.1002/ijc.30508DOI Listing
February 2017

Aberrant methylation of can be a diagnostic biomarker for lung adenocarcinoma.

J Cancer 2016 25;7(15):2280-2289. Epub 2016 Nov 25.

State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai 200433, China.

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http://dx.doi.org/10.7150/jca.15758DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166538PMC
November 2016

RICTOR polymorphisms affect efficiency of platinum-based chemotherapy in Chinese non-small-cell lung cancer patients.

Pharmacogenomics 2016 10 27;17(15):1637-1647. Epub 2016 Sep 27.

State Key Laboratory of Genetic Engineering & MOE Key Laboratory of Contemporary Anthropology, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.2217/pgs-2016-0070DOI Listing
October 2016

TNF-α Promoter Polymorphisms Predict the Response to Etanercept More Powerfully than that to Infliximab/Adalimumab in Spondyloarthritis.

Sci Rep 2016 08 31;6:32202. Epub 2016 Aug 31.

State Key Laboratory of Genetic Engineering and Ministry of Education (MOE) Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1038/srep32202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006048PMC
August 2016

Hypermethylation reduces the expression of PNPLA7 in hepatocellular carcinoma.

Oncol Lett 2016 Jul 1;12(1):670-674. Epub 2016 Jun 1.

Department of Digestive Diseases, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China; Department of Immunology of Shanghai Medical School, Institutes of Biomedical Sciences, Collaborative Innovation Center of Genetics and Development, Fudan University, Shanghai 200032, P.R. China.

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http://dx.doi.org/10.3892/ol.2016.4660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907321PMC
July 2016

Common UCP2 variants contribute to serum urate concentrations and the risk of hyperuricemia.

Sci Rep 2016 06 8;6:27279. Epub 2016 Jun 8.

State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1038/srep27279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897637PMC
June 2016

Salvianolic Acid B Attenuates Experimental Pulmonary Fibrosis through Inhibition of the TGF-β Signaling Pathway.

Sci Rep 2016 06 9;6:27610. Epub 2016 Jun 9.

State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1038/srep27610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899783PMC
June 2016

Common MIR146A Polymorphisms in Chinese Ankylosing Spondylitis Subjects and Controls.

PLoS One 2015 14;10(9):e0137770. Epub 2015 Sep 14.

State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, No. 2005 Songhu Road, Shanghai, 200438, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0137770PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569555PMC
May 2016

Copy Number Variation of HLA-DQA1 and APOBEC3A/3B Contribute to the Susceptibility of Systemic Sclerosis in the Chinese Han Population.

J Rheumatol 2016 05 1;43(5):880-6. Epub 2016 Apr 1.

From the State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University; Institute of Rheumatology, Immunology and Allergy, Fudan University; Shanghai Traditional Chinese Medicine (TCM)-Integrated Hospital; Division of Dermatology, and Division of Rheumatology, Huashan Hospital, Fudan University, Shanghai; Yiling Hospital, Shijiazhuang; Division of Rheumatology, Teaching Hospital of Chengdu University of TCM, Chengdu; Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha, China; School of Public Health, and Medical School at Houston, University of Texas, Houston, Texas, USA.S. Guo, PhD, State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, and Institute of Rheumatology, Immunology and Allergy, Fudan University; Y. Li, MS, State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University; Y. Wang, PhD, State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University; H. Chu, PhD, State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University; Y. Chen, PhD, State Key Laboratory o

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http://dx.doi.org/10.3899/jrheum.150945DOI Listing
May 2016

Association of TERT Polymorphisms with Clinical Outcome of Non-Small Cell Lung Cancer Patients.

PLoS One 2015 28;10(5):e0129232. Epub 2015 May 28.

State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0129232PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447454PMC
April 2016

Common Variants in LRP2 and COMT Genes Affect the Susceptibility of Gout in a Chinese Population.

PLoS One 2015 6;10(7):e0131302. Epub 2015 Jul 6.

Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China; Division of Rheumatology, Taixing People's Hospital, Jiangsu Province, China; Institute of Rheumatology, Immunology and Allergy, Fudan University, Shanghai, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0131302PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493088PMC
April 2016

Prevalence of Age-Related Cataract and Cataract Surgery in a Chinese Adult Population: The Taizhou Eye Study.

Invest Ophthalmol Vis Sci 2016 Mar;57(3):1193-200

Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Xuhui District, Shanghai, China 2Myopia Key Laboratory of the Health Ministry and Visual Impairment and Reconstruction Key Laboratory of Shanghai, Shanghai, China.

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http://dx.doi.org/10.1167/iovs.15-18380DOI Listing
March 2016

Association of the HLA-DRB1 with scleroderma in Chinese population.

PLoS One 2014 3;9(9):e106939. Epub 2014 Sep 3.

Division of Rheumatology and Clinical Immunogenetics, the University of Texas Medical School at Houston, Houston, TX, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0106939PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153724PMC
November 2015

Genetic Variants of the MDM2 Gene Are Predictive of Treatment-Related Toxicities and Overall Survival in Patients With Advanced NSCLC.

Clin Lung Cancer 2015 Sep 19;16(5):e37-53. Epub 2015 Feb 19.

State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, Fudan University School of Life Sciences and Fudan Taizhou Institute of Health Sciences, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.cllc.2015.02.001DOI Listing
September 2015

IL1B gene polymorphisms, age and the risk of non-small cell lung cancer in a Chinese population.

Lung Cancer 2015 Sep 23;89(3):232-7. Epub 2015 Jun 23.

National Ministry of Education Key Laboratory of Contemporary Anthropology and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, China. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2015.06.009DOI Listing
September 2015

Involvement of collagen-binding heat shock protein 47 in scleroderma-associated fibrosis.

Protein Cell 2015 Aug 20;6(8):589-598. Epub 2015 Jun 20.

Ministry of Education Key Laboratory of Contemporary Anthropology and State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, 200438 China.

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http://dx.doi.org/10.1007/s13238-015-0171-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506285PMC
August 2015

Prevalence and Causes of Visual Impairment in a Chinese Adult Population: The Taizhou Eye Study.

Ophthalmology 2015 Jul 16;122(7):1480-8. Epub 2015 May 16.

Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China; Myopia Key Laboratory of the Health Ministry, and Visual Impairment and Reconstruction Key Laboratory of Shanghai, Shanghai, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01616420150030
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http://dx.doi.org/10.1016/j.ophtha.2015.03.022DOI Listing
July 2015

FCGR3B copy number loss rather than gain is a risk factor for systemic lupus erythematous and lupus nephritis: a meta-analysis.

Int J Rheum Dis 2015 May 27;18(4):392-7. Epub 2014 Mar 27.

Ministry of Education Key Laboratory of Contemporary Anthropology and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1111/1756-185X.12342DOI Listing
May 2015

Association between a variant in microRNA-646 and the susceptibility to hepatocellular carcinoma in a large-scale population.

ScientificWorldJournal 2014 7;2014:312704. Epub 2014 Aug 7.

Department of Digestive Diseases, Huashan Hospital, Fudan University, 12 Middle Wulumuqi Road, Shanghai 200040, China ; Department of Immunology of Shanghai Medical School and Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.

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http://dx.doi.org/10.1155/2014/312704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142315PMC
May 2015

Association between ABCG2 Q141K polymorphism and gout risk affected by ethnicity and gender: a systematic review and meta-analysis.

Int J Rheum Dis 2015 May 30;18(4):382-91. Epub 2014 Dec 30.

Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China.

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http://doi.wiley.com/10.1111/1756-185X.12519
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http://dx.doi.org/10.1111/1756-185X.12519DOI Listing
May 2015

Pulmonary expression of CYP2A13 and ABCB1 is regulated by FOXA2, and their genetic interaction is associated with lung cancer.

FASEB J 2015 May 9;29(5):1986-98. Epub 2015 Feb 9.

*State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences; Institutes of Biomedical Sciences of Shanghai Medical College, Fudan University, Shanghai, China; Department of Etiology and Carcinogenesis, Cancer Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Department of Cardiothoracic Surgery, Changzheng Hospital of the Second Military Medical University, Shanghai, China; and State Key Laboratory of Proteomics, Beijing Institute of Radiation Medicine, Beijing, China

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http://dx.doi.org/10.1096/fj.14-264580DOI Listing
May 2015

Identification and validation of the methylation biomarkers of non-small cell lung cancer (NSCLC).

Clin Epigenetics 2015 22;7. Epub 2015 Jan 22.

State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University Jiangwan Campus, 2005 Songhu Road, Shanghai, 200438 China ; Fudan-Taizhou Institute of Health Sciences, 1 Yaocheng Road, Taizhou, Jiangsu 225300 China.

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http://dx.doi.org/10.1186/s13148-014-0035-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318209PMC
February 2015

Two functional loci in the promoter of EPAS1 gene involved in high-altitude adaptation of Tibetans.

Sci Rep 2014 Dec 12;4:7465. Epub 2014 Dec 12.

State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University Jiangwan Campus, 2005 Songhu Road, Shanghai 200438, P.R. China.

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http://dx.doi.org/10.1038/srep07465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264014PMC
December 2014

Heterozygote advantage of methylenetetrahydrofolate reductase polymorphisms on clinical outcomes in advanced non-small cell lung cancer (NSCLC) patients treated with platinum-based chemotherapy.

Tumour Biol 2014 Nov 8;35(11):11159-70. Epub 2014 Aug 8.

State Key Laboratory of Genetic Engineering, Fudan-VARI Genetic Epidemiology Center and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, 200433, Shanghai, China.

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http://dx.doi.org/10.1007/s13277-014-2427-6DOI Listing
November 2014

Association study of miR‑149 rs2292832 and miR‑608 rs4919510 and the risk of hepatocellular carcinoma in a large‑scale population.

Mol Med Rep 2014 Nov 4;10(5):2736-44. Epub 2014 Sep 4.

Department of Digestive Diseases, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China.

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http://dx.doi.org/10.3892/mmr.2014.2536DOI Listing
November 2014

Vertical inhibition of PI3K/Akt/mTOR signaling demonstrates in vitro and in vivo anti-fibrotic activity.

J Dermatol Sci 2014 Nov 7;76(2):104-11. Epub 2014 Sep 7.

Division of Rheumatology, Huashan Hospital, Shanghai 200040, China; Institute of Rheumatology, Immunology and Allergy, Fudan University, Shanghai 200040, China. Electronic address:

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http://dx.doi.org/10.1016/j.jdermsci.2014.08.002DOI Listing
November 2014

Hypomethylation and overexpression of ITGAL (CD11a) in CD4(+) T cells in systemic sclerosis.

Clin Epigenetics 2014 11;6(1):25. Epub 2014 Nov 11.

Department of Dermatology, Second Xiangya Hospital, Central South University, 139 Ren-Min Road, Changsha, 410011 China.

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http://dx.doi.org/10.1186/1868-7083-6-25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237764PMC
November 2014

Neanderthal origin of the haplotypes carrying the functional variant Val92Met in the MC1R in modern humans.

Mol Biol Evol 2014 Aug 10;31(8):1994-2003. Epub 2014 Jun 10.

State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, ChinaCAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences (SIBS), Chinese Academy of Sciences (CAS), Shanghai, China

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http://dx.doi.org/10.1093/molbev/msu180DOI Listing
August 2014

Identification of miR-423 and miR-499 polymorphisms on affecting the risk of hepatocellular carcinoma in a large-scale population.

Genet Test Mol Biomarkers 2014 Jul 22;18(7):516-24. Epub 2014 May 22.

1 Ministry of Education Key Laboratory of Contemporary Anthropology, Fudan University , Shanghai, China .

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http://dx.doi.org/10.1089/gtmb.2013.0510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094005PMC
July 2014

Dissection of the mechanism of traditional Chinese medical prescription-Yiqihuoxue formula as an effective anti-fibrotic treatment for systemic sclerosis.

BMC Complement Altern Med 2014 Jul 7;14:224. Epub 2014 Jul 7.

National Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, PR China.

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http://dx.doi.org/10.1186/1472-6882-14-224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226964PMC
July 2014

Significant SNPs have limited prediction ability for thyroid cancer.

Cancer Med 2014 Jun 3;3(3):731-5. Epub 2014 Mar 3.

State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, 200433, China; Human Genetics Center, University of Texas School of Public Health, Houston, Texas, 77030.

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http://dx.doi.org/10.1002/cam4.211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101765PMC
June 2014

Association between HLA-DQA1 gene copy number polymorphisms and susceptibility to rheumatoid arthritis in Chinese Han population.

J Genet 2014 Apr;93(1):215-8

State Key Laboratory of Genetic Engineering and Ministry of Education (MOE) Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai 2000080, People's Republic of China.

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http://dx.doi.org/10.1007/s12041-014-0339-2DOI Listing
April 2014

Quantitative assessment of the diagnostic role of APC promoter methylation in non-small cell lung cancer.

Clin Epigenetics 2014 Mar 24;6(1). Epub 2014 Mar 24.

Ministry of Education Key Laboratory of Contemporary Anthropology and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200433, China.

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http://dx.doi.org/10.1186/1868-7083-6-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997934PMC
March 2014