Publications by authors named "Jiu-hong Chen"

9 Publications

  • Page 1 of 1

Corrective effects of maternal extreme flexure and hip abduction combined with contralateral side-lying on persistent foetal occipito-posterior position.

Int J Nurs Pract 2018 Oct 8;24(5):e12663. Epub 2018 Jun 8.

Obstetrical Department, Affiliated Hospital of Jiangsu University, Zhenjiang, China.

Aims: To observe the corrective effects of maternal extreme flexure and hip abduction combined with contralateral side-lying on persistent foetal occipito-posterior position.

Background: Digital rotation and other methods are used for correction of a persistent foetal occipito-posterior position. However, digital rotation readily causes damage to mother and foetus, and the correction rates of other methods are low.

Design: In this observational study, pregnant women were randomly divided into 2 groups according to different postures and their outcomes were compared.

Methods: A total of 238 women with persistent foetal occipito-posterior position gave birth in our hospital between January 2015 and June 2017. Of these 238 cases, 12 women declined to participate. The 226 pregnant women were divided into study group (maternal extreme flexure and hip abduction combined with contralateral side-lying, n = 114) and control group (contralateral side-lying alone, n = 112).

Results: The correction and spontaneous labour rates were higher in the study group than in the control group (P < .05). The duration between initial and successful correction and birth process were shorter in the study group than in the control group (P < .05).

Conclusion: Maternal extreme flexure and hip abduction combined with contralateral side-lying has better correction effect on persistent foetal occipito-posterior position.
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http://dx.doi.org/10.1111/ijn.12663DOI Listing
October 2018

Assessment of pancreatic adenocarcinoma: Use of low-dose whole pancreatic CT perfusion and individualized dual-energy CT scanning.

J Med Imaging Radiat Oncol 2015 Oct 29;59(5):590-8. Epub 2015 Jul 29.

Shandong Provincial Medical Imaging Research Institute, Shandong University, Jinan, China.

Introduction: The objective of this study was to investigate the value of low-dose whole pancreatic computed tomography (CT) perfusion integrated with individualized dual-energy CT (DECT) scanning in the diagnosis of pancreatic adenocarcinoma.

Methods: Twenty patients with pancreatic adenocarcinoma underwent pancreatic CT perfusion as well as individualized dual-phase DECT pancreatic scans. Perfusion characteristics of non-tumourous pancreatic parenchyma and pancreatic adenocarcinoma were analysed. Weighted-average 120 kVp images and the optimal monoenergetic images in dual phase were reconstructed and the contrast noise ratio (CNR) of pancreas-to-tumour were compared.

Results: There were significant difference on blood flow as well as blood volume between pancreatic adenocarcinoma and the non-tumourous pancreatic parenchyma (P < 0.05), whereas no difference on permeability (P > 0.05). CNRs of pancreas-to-tumour in individualized pancreatic phase were significantly higher than those in venous phase (P < 0.05), and CNRs of optimal monoenergetic images were higher than those on weighted-average 120 kVp images (P < 0.05) in both phase. Total effective radiation dose of CT examination was around 9.32-13.75 mSv.

Conclusions: Low-dose whole pancreatic CT perfusion can provide functional information, and the individualized pancreatic phase DECT scan is the optimal method for detecting pancreatic adenocarcinomas. The integration of the two techniques has great value in clinical application.
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http://dx.doi.org/10.1111/1754-9485.12342DOI Listing
October 2015

Diagnostic Value of Prospective Electrocardiogram-triggered Dual-source Computed Tomography Angiography for Infants and Children with Interrupted Aortic Arch.

Chin Med J (Engl) 2015 May;128(9):1184-9

Department of CT, Shandong Medical Imaging Research Institute, Shandong University, Jinan, Shandong 250021, China.

Background: Accurate assessment of intra- as well as extra-cardiac malformations and radiation dosage concerns are especially crucial to infants and children with interrupted aortic arch (IAA). The purpose of this study is to investigate the value of prospective electrocardiogram (ECG)-triggered dual-source computed tomography (DSCT) angiography with low-dosage techniques in the diagnosis of IAA.

Methods: Thirteen patients with suspected IAA underwent prospective ECG-triggered DSCT scan and transthoracic echocardiography (TTE). Surgery was performed on all the patients. A five-point scale was used to assess image quality. The diagnostic accuracy of DSCT angiography and TTE was compared with the surgical findings as the reference standard. A nonparametric Chi-square test was used for comparative analysis. P <0.05 was considered as a significant difference. The mean effective radiation dose (ED) was calculated.

Results: Diagnostic DSCT images were obtained for all the patients. Thirteen IAA cases with 60 separate cardiovascular anomalies were confirmed by surgical findings. The diagnostic accuracy of TTE and DSCT for total cardiovascular malformations was 93.7% and 97.9% (P > 0.05), and that for extra-cardiac vascular malformations was 92.3% and 99.0% (P < 0.05), respectively. The mean score of image quality was 3.77 ± 0.83. The mean ED was 0.30 ± 0.04 mSv (range from 0.23 mSv to 0.39 mSv).

Conclusions: In infants and children with IAA, prospective ECG-triggered DSCT with low radiation exposure and high diagnostic efficiency has higher accuracy compared to TTE in detection of extra-cardiac vascular anomalies.
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http://dx.doi.org/10.4103/0366-6999.156109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831545PMC
May 2015

Low-dose whole organ CT perfusion of the pancreas: preliminary study.

Abdom Imaging 2014 Feb;39(1):40-7

Shandong University Shandong Provincial Medical Imaging Institute, Road jing-wu, No. 324, Jinan, Shandong, 250021, People's Republic of China.

Objectives: To investigate the feasibility of low-dose whole pancreas CT perfusion in the clinical practice.

Methods: Sixty-one patients suspected pancreatic disease underwent low-dose whole pancreas CT perfusion scan (by body weight, group A: 70 kV, 120 mAs; group B: 80 kV, 100 mAs) and the individualized pancreas scan. Forty-six patients were enrolled. Perfusion characteristics, such as, blood flow, blood volume and permeability, were analyzed. The effective radiation dose of the whole pancreas CT perfusion and the total CT scan protocol were recorded. CT findings were histologically confirmed by surgical intervention or diagnostic puncture.

Results: Of the 46 cases, 33 were pancreatic adenocarcinoma, 5 were solid-pseudo-papillary tumors of pancreas, 8 cases of pancreatic endocrine tumors on the perfusion study. There was significant interobserver agreement on the measurement of normal pancreatic CT perfusion parameters of group A (n = 28)and group B (n = 18), respectively (p > 0.05). For the normal pancreas, there was no significant difference on CT perfusion parameters between group A and group B (p > 0.05). There were significant differences on blood flow as well as blood volume between the pancreatic adenocarcinomas and the normal pancreas (p < 0.001), whereas no difference on the permeability (p > 0.05). The time to peak of the normal pancreas is 28.94 ± 4.37 s (range from 24 to 38 s). Different pancreatic tumors had different types of time attenuation curve (TAC). TACs were different between pancreatic adenocarcinomas and normal pancreas. The effective radiation dose of the whole pancreas CT perfusion of Group A and Group B were 3.60 and 4.88 mSv (DLP 246 and 325 mGy cm), respectively, and the total radiation dose was around 8.01-16.22 mSv.

Conclusions: Low-dose whole pancreatic CT perfusion can effectively reduce radiation dose, and provide the best phase for the individualized pancreas scan, which has great value in the clinical practice.
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http://dx.doi.org/10.1007/s00261-013-0045-1DOI Listing
February 2014

Computed tomography coronary angiography with a consistent dose below 2 mSv using double prospectively ECG-triggered high-pitch spiral acquisition in patients with atrial fibrillation: initial experience.

Int J Cardiovasc Imaging 2013 Aug 8;29(6):1341-9. Epub 2013 Mar 8.

Department of Cardiology, Chinese PLA General Hospital, Beijing, 100853, China.

To evaluate the feasibility and imaging quality of double prospectively ECG-triggered high-pitch spiral acquisition mode (double flash mode) for coronary computed tomography angiography (CTCA) in patients with atrial fibrillation (AF). 47 patients (11 women, 36 men; mean age 64.5 ± 12.1 years) were enrolled for CTCA examinations using a dual-source CT with 2 × 128 × 0.6 mm collimation, 0.28 s rotation time and a pitch of 3.4. Double flash mode was prospectively triggered first at 60 % and later at 30 % of the R-R interval within two cardiac cycles. Image quality was evaluated using a four-point scale (1 = excellent, 4 = non-assessable). From 672 coronary artery segments, 77.5 % (521/672) was rated as score of 1, 20.8 % (140/672) as score of 2, 1.2 % (8/672) as score of 3 and 0.4 % (3/672) was rated as 'non-assessable'. The average image quality score was 1.25 ± 0.38 on a per segment basis. Mean dose-length product for CTCA was 92.6 ± 28.2 mGy cm, the effective dose was 1.30 ± 0.39 mSv (0.64-1.97 mSv). In patients with AF, double prospectively ECG-triggered high-pitch spiral acquisition mode could be a feasible and valuable scan mode for CTCA with a consistent dose below 2 mSv as well as diagnostic imaging quality.
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http://dx.doi.org/10.1007/s10554-013-0203-0DOI Listing
August 2013

Prospectively electrocardiogram-gated high-pitch spiral acquisition mode dual-source CT coronary angiography in patients with high heart rates: comparison with retrospective electrocardiogram-gated spiral acquisition mode.

Korean J Radiol 2012 Nov-Dec;13(6):684-93. Epub 2012 Oct 12.

Department of Radiology, Baotou Central Hospital, Inner Mongolia, Baotou 014040, China.

Objective: To assess the image quality and effective radiation dose of prospectively electrocardiogram (ECG)-gated high-pitch spiral acquisition mode (flash mode) of dual-source CT (DSCT) coronary angiography (CTCA) in patients with high heart rates (HRs) as compared with retrospectively ECG-gated spiral acquisition mode.

Materials And Methods: Two hundred and sixty-eight consecutive patients (132 female, mean age: 55 ± 11 years) with mean HR > 65 beats per minute (bpm) were prospectively included in this study. The patients were divided into two groups. Collection was performed in group A CTCA using flash mode setting at 20-30% of the R-R interval, and retrospectively ECG-gated spiral acquisition mode in group B. The image noise, contrast-to-noise ratio (CNR), image quality scores, effective radiation dose and influencing factors on image quality between the two groups were assessed.

Results: There were no significant differences in image quality scores and proportions of non-diagnostic coronary artery segments between two groups (image quality scores: 1.064 ± 0.306 [group A] vs. 1.084 ± 0.327 [group B], p = 0.063; proportion of non-diagnostic coronary artery segments: segment-based analysis 1.52% (group A) vs. 1.74% (group B), p = 0.345; patient-based analysis 7.5% (group A) vs. 6.7% (group B), p = 0.812). The estimated radiation dose was 1.0 ± 0.16 mSv in group A and 7.1 ± 1.05 mSv in group B (p = 0.001).

Conclusion: In conclusion, in patients with HRs > 65 bpm without cardiac arrhythmia, the prospectively high-pitch spiral-acquisition mode with image-acquired timing set at 20-30% of the R-R interval provides a similar image quality and low rate of non-diagnostic coronary segments to the retrospectively ECG-gated low-pitch spiral acquisition mode, with significant reduction of radiation exposure.
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http://dx.doi.org/10.3348/kjr.2012.13.6.684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484288PMC
April 2013

Myocardial bridging on dual-source computed tomography: degree of systolic compression of mural coronary artery correlating with length and depth of the myocardial bridge.

Clin Imaging 2010 Mar-Apr;34(2):83-8

Shandong Medical Imaging Research Institute, Shandong University, Road Jing-Wu, No. 324, Jinan, 250021, PR China.

Objective: To investigate the correlation between the degree of systolic compression of mural coronary artery (MCA) and the length and depth of myocardial bridging (MB) with dual-source computed tomography (DSCT).

Methods: The length and depth of MB were measured from diastolic phase. All datasets were reconstructed in 5% steps of R-R interval. The optimum phases were chosen where the maximal and minimal diameters were shown. The degree of systolic compression of MCA was calculated. The correlation between length and depth of MB and the degree of systolic compression of MCA were analyzed by Pearson test.

Results: The minimal diameters were found in 27 sites (90.0%) from 30% to 35% R-R interval, and the maximal diameters were found in 27 sites (90.0%) from 70% to 80% R-R interval. The correlation between systolic compression of MCA and length of MB was not significant (r=0.096, P=.613); however, the correlation between systolic compression of MCA and the depth of MB was significant (r=0.675, P<.01).

Conclusion: The minimal and maximal diameters of MCA are usually demonstrated in 30-35% and 70-80% R-R reconstruction interval, respectively. The degree of systolic compression of MCA correlates well with the depth of MB.
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http://dx.doi.org/10.1016/j.clinimag.2009.05.010DOI Listing
June 2010

Dose performance and image quality: dual source CT versus single source CT in cardiac CT angiography.

Eur J Radiol 2009 Dec 2;72(3):396-400. Epub 2008 Oct 2.

Shandong University Medical College, Shandong Medical Imaging Research Institute, Jinan, Shandong 250012, PR China.

Objective: To evaluate dose performance and image quality of 64-slice dual source CT (DSCT) in comparison to 64-slice single source CT (SSCT) in cardiac CT angiography (CTA).

Methods: 100 patients examined by DSCT and 60 patients scanned by SSCT were included in this study. Objective indices such as image noise, contrast-to-noise ratio and signal-to-noise ratio were analyzed. Subjective image quality was assessed by two cardiovascular radiologists in consensus using a four-point scale (1=excellent to 4=not acceptable). Estimation of effective dose was performed on the basis of dose length product (DLP).

Results: At low heart rates (<70 bpm), image quality of SSCT was equivalent to that of DSCT (P>0.05), but, at high heart rates (>70 bpm), DSCT provided robust image quality (P<0.05). The average effective dose of SSCT was 9.3+/-0.9 mSv at low heart rates (<70 bpm) while, the average estimated effective doses of DSCT were 9.1+/-1.3 mSv, 8.3+/-1.1 mSv, 7.9+/-1.1 mSv, 6.9+/-0.7 mSv, and 5.9+/-1.3 mSv, corresponding to heart rates of 50-59 bpm, 60-69 bpm, 70-79 bpm, 80-89 bpm, and 90-100 bpm.

Conclusion: For cardiac CTA, both DSCT and SSCT can get good image quality at low heart rates (<70 bpm) with a similar radiation dose, but, at high heart rates (>70 bpm), DSCT is able to provide robust diagnostic image quality at doses far below that of SSCT.
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http://dx.doi.org/10.1016/j.ejrad.2008.08.010DOI Listing
December 2009

Spectrum of functioning islet cell tumor on multislice computed tomography: experience on 70 patients.

Chin Med Sci J 2008 Mar;23(1):1-9

Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730.

Objective: To review experience in preoperative detection of islet cell tumors using multislice computed tomography (MSCT) and summarize various imaging features of functioning islet cell tumors on enhanced MSCT.

Methods: Seventy patients with clinical or pathological diagnosis of functioning pancreatic islet cell tumor between October 2003 and February 2007 were included in this retrospective study. Seventy-four enhanced MSCT scans in these patients were identified. All MSCT scans were interpreted by two experienced radiologists by consensus interpretation. Surgery and pathology reports were used to confirm the diagnosis, localization, and size of tumors.

Results: Totally, 73 functioning islet cell tumors including 65 benign insulinomas, 2 benign glucagonomas, 3 malignant insulinomas, and 3 malignant glucagonomas were pathologically diagnosed. Tumors in only two cases were not found by MSCT. In 67 benign lesions, 32 showed typical enhancement style, 21 showed prolonged enhancement in portal venous phase, 4 showed delayed enhancement, 4 had iso-dense enhancement with normal pancreatic parenchyma, 2 had no enhancement at all in arterial phase and portal venous phase, and 4 had inhomogeneous enhancement with necrosis or cyst-formation. Patchy or spotty calcifications were found in 3 of the 67 tumors. In 6 malignant islet cell tumors, vessel invasion (2/6) and bowel invasion (1/6) were seen. Different enhancement patterns were shown. All hepatic metastases showed hyper-enhancement during their arterial phase.

Conclusions: Pancreatic islet cell tumor may display a wide spectrum of presentations in MSCT. Tumors with unusual appearances often present as diagnostic challenges. Non-contrast and post-contrast multiphase scans are recommended for the localization of functioning islet cell tumors.
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http://dx.doi.org/10.1016/s1001-9294(09)60001-8DOI Listing
March 2008
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