Jiri Litzman

Paediatric Immunology Unit, Department of Paediatric Pulmonology, Allergology and Neonatology, Hanover Medical School, Carl-Neuberg Str. 1, 30625, Hannover, Germany.

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February 2019

Clinical Efficacy, Safety and Tolerability of a New Subcutaneous Immunoglobulin 16.5% (Octanorm [Cutaquig®]) in the Treatment of Patients With Primary Immunodeficiencies.

Authors:

Roger H Kobayashi Sudhir Gupta Isaac Melamed J Fernando Mandujano Ai Lan Kobayashi Bruce Ritchie Bob Geng Thomas Prescott Atkinson Syed Rehman Eva Turpel-Kantor Jiří Litzman

Front Immunol 2019 4;10:40. Epub 2019 Feb 4.

Department of Clinical Immunology and Allergology, St Anne's University Hospital in Brno, Faculty of Medicine, Masaryk University, Brno, Czechia.

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December 2019

CVID-Associated Tumors: Czech Nationwide Study Focused on Epidemiology, Immunology, and Genetic Background in a Cohort of Patients With CVID.

Authors:

Pavlina Kralickova Tomas Milota Jiri Litzman Ivana Malkusova Dalibor Jilek Jitka Petanova Jana Vydlakova Alena Zimulova Eva Fronkova Michael Svaton Veronika Kanderova Marketa Bloomfield Zuzana Parackova Adam Klocperk Jiri Haviger Tomas Kalina Anna Sediva

Front Immunol 2018 22;9:3135. Epub 2019 Jan 22.

Department of Immunology, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czechia.

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October 2019

Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group.

J Clin Immunol 2019 01 13;39(1):45-54. Epub 2018 Dec 13.

Paediatric Immunology Unit, Department of Paediatric Pulmonology, Allergology and Neonatology, Hanover Medical School, Carl-Neuberg Str. 1, 30625, Hannover, Germany.

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January 2019

Neutrophil and Granulocytic Myeloid-Derived Suppressor Cell-Mediated T Cell Suppression Significantly Contributes to Immune Dysregulation in Common Variable Immunodeficiency Disorders.

Authors:

Marcela Vlkova Zita Chovancova Jana Nechvatalova Ashley Nicole Connelly Marcus Darrell Davis Peter Slanina Lucie Travnickova Marek Litzman Tereza Grymova Premysl Soucek Tomas Freiberger Jiri Litzman Zdenek Hel

J Immunol 2019 01 28;202(1):93-104. Epub 2018 Nov 28.

Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35249.

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January 2019

Treatment of Hereditary Angioedema Attacks with Icatibant and Recombinant C1 Inhibitor During Pregnancy.

Authors:

Roman Hakl Pavel Kuklínek Irena Krčmová Pavlína Králíčková Tomáš Freiberger Petr Janků Marcela Vlková Jiří Litzman

J Clin Immunol 2018 10 2;38(7):810-815. Epub 2018 Oct 2.

Department of Clinical Immunology and Allergology, St. Anne's University Hospital in Brno, Brno, Czech Republic.

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October 2018

Hyper-IgE in the allergy clinic--when is it primary immunodeficiency?

Authors:

Mark J Ponsford Adam Klocperk Federica Pulvirenti Virgil A S H Dalm Tomas Milota Francesco Cinetto Zita Chovancova Manuel J Rial Anna Sediva Jiri Litzman Carlo Agostini Martin van Hagen Isabella Quinti Stephen Jolles

Allergy 2018 11 2;73(11):2122-2136. Epub 2018 Oct 2.

Immunodeficiency Centre for Wales, Cardiff, UK.

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November 2018

Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects.

Authors:

Charlotte Schwab Annemarie Gabrysch Peter Olbrich Virginia Patiño Klaus Warnatz Daniel Wolff Akihiro Hoshino Masao Kobayashi Kohsuke Imai Masatoshi Takagi Ingunn Dybedal Jamanda A Haddock David M Sansom Jose M Lucena Maximilian Seidl Annette Schmitt-Graeff Veronika Reiser Florian Emmerich Natalie Frede Alla Bulashevska Ulrich Salzer Desirée Schubert Seiichi Hayakawa Satoshi Okada Maria Kanariou Zeynep Yesim Kucuk Hugo Chapdelaine Lenka Petruzelkova Zdenek Sumnik Anna Sediva Mary Slatter Peter D Arkwright Andrew Cant Hanns-Martin Lorenz Thomas Giese Vassilios Lougaris Alessandro Plebani Christina Price Kathleen E Sullivan Michel Moutschen Jiri Litzman Tomas Freiberger Frank L van de Veerdonk Mike Recher Michael H Albert Fabian Hauck Suranjith Seneviratne Jana Pachlopnik Schmid Antonios Kolios Gary Unglik Christian Klemann Carsten Speckmann Stephan Ehl Alan Leichtner Richard Blumberg Andre Franke Scott Snapper Sebastian Zeissig Charlotte Cunningham-Rundles Lisa Giulino-Roth Olivier Elemento Gregor Dückers Tim Niehues Eva Fronkova Veronika Kanderová Craig D Platt Janet Chou Talal A Chatila Raif Geha Elizabeth McDermott Su Bunn Monika Kurzai Ansgar Schulz Laia Alsina Ferran Casals Angela Deyà-Martinez Sophie Hambleton Hirokazu Kanegane Kjetil Taskén Olaf Neth Bodo Grimbacher

J Allergy Clin Immunol 2018 12 4;142(6):1932-1946. Epub 2018 May 4.

Center for Chronic Immunodeficiency (CCI), Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Institute of Immunology and Transplantation, Royal Free Hospital, University College London, London, United Kingdom. Electronic address:

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December 2018

-Mutant Specific Granule Deficiency Correlates With Aberrant Granule Organization and Substantial Proteome Alterations in Neutrophils.

Authors:

Nina K Serwas Jakob Huemer Régis Dieckmann Ester Mejstrikova Wojciech Garncarz Jiri Litzman Birgit Hoeger Ondrej Zapletal Ales Janda Keiryn L Bennett Renate Kain Dontscho Kerjaschky Kaan Boztug

Front Immunol 2018 29;9:588. Epub 2018 Mar 29.

Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Vienna, Austria.

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May 2019

Terminally differentiated memory T cells are increased in patients with common variable immunodeficiency and selective IgA deficiency.

Authors:

Jana Nechvatalova Tomas Pavlik Jiri Litzman Marcela Vlkova

Cent Eur J Immunol 2017 30;42(3):244-251. Epub 2017 Oct 30.

Department of Clinical Immunology and Allergology, St Anne's University Hospital, and Faculty of Medicine, Masaryk University, Brno, Czech Republic.

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October 2017

Selective IgM Deficiency: Clinical and Laboratory Features of 17 Patients and a Review of the Literature.

Authors:

Zita Chovancova Pavlina Kralickova Alena Pejchalova Marketa Bloomfield Jana Nechvatalova Marcela Vlkova Jiri Litzman

J Clin Immunol 2017 Aug 21;37(6):559-574. Epub 2017 Jul 21.

Department of Clinical Immunology and Allergy, St. Anne's University Hospital in Brno, Pekarska 53, 65691, Brno, Czech Republic.

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August 2017

Erratum: Common Variable Immunodeficiency patients with a phenotypic profile of immunosenescence present with thrombocytopenia.

Authors:

Jan Stuchlý Veronika Kanderová Marcela Vlková Ivana Heřmanová Lucie Slámová Ondřej Pelák Eli Taraldsrud Dalibor Jílek Pavlína Králíčková Børre Fevang Marie Trková Ondřej Hrušák Eva Froňková Anna Šedivá Jiří Litzman Tomáš Kalina

Sci Rep 2017 02 27;7:42569. Epub 2017 Feb 27.

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February 2017

Common Variable Immunodeficiency patients with a phenotypic profile of immunosenescence present with thrombocytopenia.

Authors:

Jan Stuchlý Veronika Kanderová Marcela Vlková Ivana Heřmanová Lucie Slámová Ondřej Pelák Eli Taraldsrud Dalibor Jílek Pavlína Králíc Ková Børre Fevang Marie Trková Ondřej Hrušák Eva Froňková Anna Šedivá Jiří Litzman Tomáš Kalina

Sci Rep 2017 01 5;7:39710. Epub 2017 Jan 5.

CLIP - Childhood Leukemia Investigation Prague, Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.

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January 2017

Common variants at PVT1, ATG13-AMBRA1, AHI1 and CLEC16A are associated with selective IgA deficiency.

Authors:

Paola G Bronson Diana Chang Tushar Bhangale Michael F Seldin Ward Ortmann Ricardo C Ferreira Elena Urcelay Luis Fernández Pereira Javier Martin Alessandro Plebani Vassilios Lougaris Vanda Friman Tomáš Freiberger Jiri Litzman Vojtech Thon Qiang Pan-Hammarström Lennart Hammarström Robert R Graham Timothy W Behrens

Nat Genet 2016 11 10;48(11):1425-1429. Epub 2016 Oct 10.

Department of Human Genetics, Genentech, Inc., South San Francisco, California, USA.

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November 2016

Infectious Complications and Immune/Inflammatory Response in Cardiogenic Shock Patients: A Prospective Observational Study.

Authors:

Jiri Parenica Jiri Jarkovsky Jan Malaska Alexandre Mebazaa Jana Gottwaldova Katerina Helanova Jiri Litzman Milan Dastych Josef Tomandl Jindrich Spinar Ludmila Dostalova Petr Lokaj Marie Tomandlova Monika Goldergova Pavkova Pavel Sevcik Matthieu Legrand

Shock 2017 02;47(2):165-174

*Department of Internal Medicine and Cardiology, University Hospital Brno, Brno, Czech Republic †Faculty of Medicine, Masaryk University, Brno, Czech Republic ‡Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Brno, Czech Republic §Department of Anaesthesiology and Intensive Care, University Hospital Brno, Brno, Czech Republic ¶Université Paris Diderot, PRES Sorbonne Paris Cité, France ||Department of Anaesthesiology and Critical Care and Burn unit, APHP, Saint Louis Lariboisière University Hospitals, Paris, France #U 942 INSERM, Paris, France **Department of Biochemistry, University Hospital Brno, Brno, Czech Republic ††Department of Laboratory Methods, Faculty of Medicine, Masaryk University, Brno, Czech Republic ‡‡Department of Clinical Immunology and Allergology, St Anne's University Hospital in Brno, Brno, Czech Republic §§Department of Biochemistry, Faculty of Medicine, Masaryk University, Brno, Czech Republic ¶¶Department of Pathological Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic ||||Department of Anaesthesiology and Intensive Care, University Hospital Ostrava, Ostrava-Poruba, Czech Republic.

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February 2017

Long-term outcomes of 176 patients with X-linked hyper-IgM syndrome treated with or without hematopoietic cell transplantation.

Authors:

M Teresa de la Morena David Leonard Troy R Torgerson Otavio Cabral-Marques Mary Slatter Asghar Aghamohammadi Sharat Chandra Luis Murguia-Favela Francisco A Bonilla Maria Kanariou Rongras Damrongwatanasuk Caroline Y Kuo Christopher C Dvorak Isabelle Meyts Karin Chen Lisa Kobrynski Neena Kapoor Darko Richter Daniela DiGiovanni Fatima Dhalla Evangelia Farmaki Carsten Speckmann Teresa Español Anna Shcherbina Imelda Celine Hanson Jiri Litzman John M Routes Melanie Wong Ramsay Fuleihan Suranjith L Seneviratne Trudy N Small Ales Janda Liliana Bezrodnik Reinhard Seger Andrea Gomez Raccio J David M Edgar Janet Chou Jordan K Abbott Joris van Montfrans Luis Ignacio González-Granado Nancy Bunin Necil Kutukculer Paul Gray Gisela Seminario Srdjan Pasic Victor Aquino Christian Wysocki Hassan Abolhassani Morna Dorsey Charlotte Cunningham-Rundles Alan P Knutsen John Sleasman Beatriz Tavares Costa Carvalho Antonio Condino-Neto Eyal Grunebaum Helen Chapel Hans D Ochs Alexandra Filipovich Mort Cowan Andrew Gennery Andrew Cant Luigi D Notarangelo Chaim M Roifman

J Allergy Clin Immunol 2017 Apr 30;139(4):1282-1292. Epub 2016 Sep 30.

Hospital for Sick Children, Toronto, Ontario, Canada.

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April 2017

Secondary Combined Immunodeficiency in Pediatric Patients after the Fontan Operation: Three Case Reports.

Authors:

Eva Hlavackova Martin Liska Hana Jicinska Jiri Navratil Jiri Litzman

Int Arch Allergy Immunol 2016 30;170(4):251-256. Epub 2016 Sep 30.

Department of Clinical Immunology and Allergology, St. Anne's University Hospital, Brno, Czech Republic.

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February 2017

Prognosis of Good syndrome: mortality and morbidity of thymoma associated immunodeficiency in perspective.

Authors:

Anne Jansen Marcel van Deuren Joanne Miller Jiri Litzman Javier de Gracia Matías Sáenz-Cuesta Anna Szaflarska Timi Martelius Yuichi Takiguchi Smita Patel Siraj Misbah Anna Simon

Clin Immunol 2016 Oct 4;171:12-17. Epub 2016 Aug 4.

Nijmegen Center for Immunodeficiency and Autoinflammation (NCIA), Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.

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October 2016

Role of Flow Cytometry in the Diagnosis of Chronic Granulomatous Disease: the Egyptian Experience.

Authors:

Rabab El Hawary Safa Meshaal Caroline Deswarte Nermeen Galal Mahitab Abdelkawy Radwa Alkady Dalia Abd Elaziz Tomas Freiberger Barbora Ravcukova Jiri Litzman Jacinta Bustamante Jeannette Boutros Taghrid Gaafar Aisha Elmarsafy

J Clin Immunol 2016 08 24;36(6):610-8. Epub 2016 May 24.

Pediatrics Department, Faculty of Medicine, Cairo University, Cairo, Egypt.

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August 2016

Pregnancy Outcome in Patients with Common Variable Immunodeficiency.

Authors:

Pavlina Kralickova Barbora Kurecova Ctirad Andrys Irena Krcmova Dalibor Jilek Marcela Vlkova Jiri Litzman

J Clin Immunol 2015 Aug 18;35(6):531-7. Epub 2015 Aug 18.

Departmant of Clinical Immunology and Allergology, St. Anne's University Hospital, Pekařská 53, 65691, Brno, Czech Republic.

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August 2015

Regulatory B cells in CVID patients fail to suppress multifunctional IFN-γ+ TNF-α+ CD4+ T cells differentiation.

Authors:

Marcela Vlkova Olga Ticha Jana Nechvatalova Tomas Kalina Jiri Litzman Claudia Mauri Paul A Blair

Clin Immunol 2015 Oct 29;160(2):292-300. Epub 2015 Jul 29.

Centre for Rheumatology Research, Division of Medicine, University College London, 5 University Street, London WC1E 6JF, UK.

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October 2015

Successful renal transplantation in a patient with a Wiskott-Aldrich syndrome protein (WASP) gene mutation.

Authors:

Zita Chovancova Milan Kuman Marcela Vlkova Jiri Litzman

Transpl Int 2015 Aug 30;28(8):1005-9. Epub 2015 Apr 30.

Department of Clinical Immunology and Allergy, St. Anne's University Hospital, Brno, Czech Republic.

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August 2015

Detection of impaired IgG antibody formation facilitates the decision on early immunoglobulin replacement in hypogammaglobulinemic patients.

Authors:

Hermann M Wolf Vojtech Thon Jiri Litzman Martha M Eibl

Front Immunol 2015 2;6:32. Epub 2015 Feb 2.

Immunology Outpatient Clinic , Vienna , Austria.

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February 2015

Altered serum cytokine signature in common variable immunodeficiency.

Authors:

Zdenek Hel Richard P H Huijbregts Jun Xu Jana Nechvatalova Marcela Vlkova Jiri Litzman

J Clin Immunol 2014 Nov 23;34(8):971-8. Epub 2014 Sep 23.

Department of Pathology and Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA.

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November 2014

[Dynamics of interleukin 6 levels in the patients with cardiogenic and septic shock and in a control group of patients with uncomplicated AMI].

Authors:

Jiří Pařenica Jan Maláska Jiří Jarkovský Kateřina Helánová Petr Jabandžiev Jaroslav Michálek Zuzana Veselková Simona Littnerová Lenka Kubková Roman Gál Pavel Sevčík Monika Pávková Goldbergová Jiří Litzman Zdena Čermáková Jindřich Špinar

Vnitr Lek 2014 Feb;60(2):114-22

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February 2014

Clinical picture and treatment of 2212 patients with common variable immunodeficiency.

J Allergy Clin Immunol 2014 Jul 28;134(1):116-26. Epub 2014 Feb 28.

Center for Chronic Immunodeficiency (CCI), University Medical Centre Freiburg and University of Freiburg, Freiburg, Germany; UCL Medical School Royal Free Campus and Royal Free Hospital NHS Foundation Trust, London, United Kingdom. Electronic address:

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July 2014

Cytomegalovirus disease in patients with common variable immunodeficiency: three case reports.

Authors:

Pavlina Kralickova Eva Mala Doris Vokurkova Irena Krcmova Lenka Pliskova Vlasta Stepanova Vladimir Bartos Vladimir Koblizek Ilja Tacheci Jan Bures Jan Brozik Jiri Litzman

Int Arch Allergy Immunol 2014 16;163(1):69-74. Epub 2013 Nov 16.

Institute of Clinical Immunology and Allergy, University Hospital Hradec Kralove, Faculty of Medicine, Charles University in Prague, Hradec Kralove, Czech Republic.

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March 2014

New and recurrent gain-of-function STAT1 mutations in patients with chronic mucocutaneous candidiasis from Eastern and Central Europe.

J Med Genet 2013 Sep 24;50(9):567-78. Epub 2013 May 24.

Department of Infectious and Pediatric Immunology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary, EU.

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September 2013

B-lymphocyte subpopulations in patients with selective IgA deficiency.

Authors:

Jana Nechvatalova Zdenka Pikulova Dagmar Stikarovska Sava Pesak Marcela Vlkova Jiri Litzman

J Clin Immunol 2012 Jun 12;32(3):441-8. Epub 2012 Feb 12.

Department of Clinical Immunology and Allergology, St. Anne's University Hospital, Faculty of Medicine, Masaryk University, Pekarska 53, 656 91, Brno, Czech Republic.

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June 2012

Soluble ST2 levels in patients with cardiogenic and septic shock are not predictors of mortality.

Authors:

Jiri Parenica Jan Malaska Jiri Jarkovsky Jolana Lipkova Milan Dastych Katerina Helanova Jiri Litzman Josef Tomandl Simona Littnerova Jana Sevcikova Roman Gal Pavel Sevcik Jindrich Spinar Monika Pavkova Goldbergova

Exp Clin Cardiol 2012 ;17(4):205-9

Department of Internal Cardiology Medicine, University Hospital Brno, Brno, Czech Republic ; Faculty of Medicine, Masaryk University, Brno, Czech Republic ; International Clinical Research Cente, Department of Cardiovascular Disease, University Hospital St Anne's, Brno, Czech Republic.

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April 2013

Soluble BAFF levels inversely correlate with peripheral B cell numbers and the expression of BAFF receptors.

Authors:

Matthias Kreuzaler Melanie Rauch Ulrich Salzer Jennifer Birmelin Marta Rizzi Bodo Grimbacher Alessandro Plebani Vassilios Lougaris Isabella Quinti Vojtech Thon Jiri Litzman Michael Schlesier Klaus Warnatz Jens Thiel Antonius G Rolink Hermann Eibel

J Immunol 2012 Jan 28;188(1):497-503. Epub 2011 Nov 28.

Department of Biomedicine, University of Basel, 4058 Basel, Switzerland.

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January 2012

Antibody forming cells and plasmablasts in peripheral blood in CVID patients after vaccination.

Authors:

Zita Chovancova Marcela Vlkova Jiri Litzman Jindrich Lokaj Vojtech Thon

Vaccine 2011 May 5;29(24):4142-50. Epub 2011 Apr 5.

Department of Clinical Immunology and Allergy, Medical Faculty of Masaryk University, University Centre for Primary Immunodeficiencies, St. Anne's University Hospital, Pekarska 53, CZ-656 91 Brno, Czech Republic.

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May 2011

Recurrent laryngeal papillomatosis: successful treatment with human papillomavirus vaccination.

Authors:

Peter Mudry Martin Vavrina Pavel Mazanek Michaela Machalova Jiri Litzman Jaroslav Sterba

Arch Dis Child 2011 May 10;96(5):476-7. Epub 2011 Jan 10.

Department of Paediatric Oncology, University Children's Hospital Brno, Cernopolni 9, Brno, Czech Republic.

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May 2011

Characterization of lymphocyte subsets in patients with common variable immunodeficiency reveals subsets of naive human B cells marked by CD24 expression.

Authors:

Marcela Vlková Eva Fronková Veronika Kanderová Ales Janda Sárka Ruzicková Jirí Litzman Anna Sedivá Tomás Kalina

J Immunol 2010 Dec 1;185(11):6431-8. Epub 2010 Nov 1.

Department of Clinical Immunology and Allergology, St. Anne's University Hospital and Faculty of Medicine, Masaryk University, Brno, Czech Republic.

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December 2010

Monitoring of CD38high expression in peripheral blood CD8+ lymphocytes in patients after kidney transplantation as a marker of cytomegalovirus infection.

Authors:

Olga Ticha Martina Stouracova Milan Kuman Pavel Studenik Tomas Freiberger Jiri Litzman

Transpl Immunol 2010 Oct 14;24(1):50-6. Epub 2010 Oct 14.

Department of Clinical Immunology and Allergology, St. Anne's Faculty Hospital, Masaryk University, Brno, Czech Republic.

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October 2010

Change in referral diagnoses and diagnostic delay in hypogammaglobulinaemic patients during 28 years in a single referral centre.

Authors:

Jiri Litzman Dagmar Stikarovska Zdenka Pikulova Tomas Pavlik Sava Pesak Vojtech Thon Pavel Kuklinek Jindrich Lokaj

Int Arch Allergy Immunol 2010 1;153(1):95-101. Epub 2010 Apr 1.

Department of Clinical Immunology and Allergology, Faculty of Medicine, Masaryk University, St. Anne's Faculty Hospital, Pekarska, Brno, Czech Republic.

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September 2010

Mutations in STAT3 and diagnostic guidelines for hyper-IgE syndrome.

J Allergy Clin Immunol 2010 Feb;125(2):424-432.e8

Department of Immunology and Molecular Pathology, Royal Free Hospital, University College London, London NW3 2QG, United Kingdom.

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February 2010

Profiling of polychromatic flow cytometry data on B-cells reveals patients' clusters in common variable immunodeficiency.

Authors:

Tomás Kalina Jan Stuchlý Ales Janda Ondrej Hrusák Sárka Růzicková Anna Sedivá Jirí Litzman Marcela Vlková

Cytometry A 2009 Nov;75(11):902-9

Department of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University Prague and University Hospital Motol, Prague, Czech Republic.

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November 2009