Jingshan Shi

Jingshan Shi

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A comprehensive review on fungal endophytes and its dynamics on Orchidaceae plants: current research, challenges, and future possibilities.

Bioengineered 2019 12;10(1):316-334

b Bioresource Institute for Healthy Utilization, Zunyi Medical University , Zunyi , China.

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http://dx.doi.org/10.1080/21655979.2019.1644854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682353PMC
December 2019

Microbial dynamics for lignocellulosic waste bioconversion and its importance with modern circular economy, challenges and future perspectives.

Bioresour Technol 2019 Nov 27;291:121905. Epub 2019 Jul 27.

Key Laboratory of Basic Pharmacology and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi 563003, China.

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http://dx.doi.org/10.1016/j.biortech.2019.121905DOI Listing
November 2019

Induction of Nrf2 pathway by Dendrobium nobile Lindl. alkaloids protects against carbon tetrachloride induced acute liver injury.

Biomed Pharmacother 2019 Sep 15;117:109073. Epub 2019 Jun 15.

Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnocentric of Ministry of Education, Zunyi Medical University, Zunyi, Guizhou, 563003, China. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2019.109073DOI Listing
September 2019

Resveratrol delays 6-hydroxydopamine-induced apoptosis by activating the PI3K/Akt signaling pathway.

Exp Gerontol 2019 Sep 8;124:110653. Epub 2019 Jul 8.

Key Laboratory of Basic Pharmacology and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Guizhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.exger.2019.110653DOI Listing
September 2019

Icariin improves the cognitive function of APP/PS1 mice via suppressing endoplasmic reticulum stress.

Life Sci 2019 Aug 7:116739. Epub 2019 Aug 7.

Key Laboratory of Basic Pharmacology of Ministry of Education, Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, Guizhou, China.

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http://dx.doi.org/10.1016/j.lfs.2019.116739DOI Listing
August 2019

Procyanidin protects against 6-hydroxydopamine-induced dopaminergic neuron damage via the regulation of the PI3K/Akt signalling pathway.

Biomed Pharmacother 2019 Jun 27;114:108789. Epub 2019 Mar 27.

Key Laboratory of Basic Pharmacology and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Guizhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2019.108789DOI Listing
June 2019

Icariin protects rotenone-induced neurotoxicity through induction of SIRT3.

Toxicol Appl Pharmacol 2019 Jun 25;379:114639. Epub 2019 Jun 25.

Joint International Research Laboratory of Ethnomedicine, Zunyi Medical University, Zunyi, Guizhou, China; Key Laboratory of Basic Pharmacology of Ministry of Education, Zunyi Medical University, Zunyi, Guizhou, China; Department of Environmental Health, Indiana University, Bloomington, IN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2019.114639DOI Listing
June 2019

Icariin-mediated activation of autophagy confers protective effect on rotenone induced neurotoxicity in vivo and in vitro.

Toxicol Rep 2019 25;6:637-644. Epub 2019 Jun 25.

Joint International Research Laboratory of Ethnomedicine, Zunyi Medical University, Zunyi, Guizhou, China.

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http://dx.doi.org/10.1016/j.toxrep.2019.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624214PMC
June 2019

Activation of Nrf2 signaling by Icariin protects against 6-OHDA-induced neurotoxicity.

Biotechnol Appl Biochem 2019 May 5;66(3):465-471. Epub 2019 Apr 5.

Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, Guizhou, People's Republic of China.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/bab.1743
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http://dx.doi.org/10.1002/bab.1743DOI Listing
May 2019

Icariside II attenuates lipopolysaccharide-induced neuroinflammation through inhibiting TLR4/MyD88/NF-κB pathway in rats.

Biomed Pharmacother 2019 Mar 24;111:315-324. Epub 2018 Dec 24.

Key Laboratory of Basic Pharmacology of Ministry of Education, Zunyi Medical University, Zunyi, Guizhou, 563000, China; Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, Guizhou, 563003, China. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2018.10.201DOI Listing
March 2019

Management of Diabetes Mellitus with Puerarin, a Natural Isoflavone From Pueraria lobata.

Am J Chin Med 2018 10;46(8):1771-1789. Epub 2018 Dec 10.

* Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi 563003, P. R. China.

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https://www.worldscientific.com/doi/abs/10.1142/S0192415X185
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http://dx.doi.org/10.1142/S0192415X18500891DOI Listing
February 2019

Nuclear accumulation of UBC9 contributes to SUMOylation of lamin A/C and nucleophagy in response to DNA damage.

J Exp Clin Cancer Res 2019 Feb 11;38(1):67. Epub 2019 Feb 11.

College of Pharmacy, Army Medical University, Chongqing, 400038, China.

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http://dx.doi.org/10.1186/s13046-019-1048-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371487PMC
February 2019

CZ2HF mitigates β-amyloid 25-35 fragment-induced learning and memory impairment through inhibition of neuroinflammation and apoptosis in rats.

Int J Mol Med 2019 Jan 24;43(1):557-566. Epub 2018 Oct 24.

Key Laboratory of Basic Pharmacology of Ministry of Education, Department of Pharmacology, Zunyi Medical University, Zunyi, Guizhou 563000, P.R. China.

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http://www.spandidos-publications.com/10.3892/ijmm.2018.3952
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http://dx.doi.org/10.3892/ijmm.2018.3952DOI Listing
January 2019

Lithocarpus polystachyus Rehd. leaves aqueous extract protects against hydrogen peroxide‑induced SH-SY5Y cells injury through activation of Sirt3 signaling pathway.

Int J Mol Med 2018 Dec 5;42(6):3485-3494. Epub 2018 Oct 5.

Department of Pharmacology, Key Laboratory of Basic Pharmacology of Ministry of Education, Zunyi Medical University, Zunyi, Guizhou 563000, P.R. China.

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http://www.spandidos-publications.com/10.3892/ijmm.2018.3916
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http://dx.doi.org/10.3892/ijmm.2018.3916DOI Listing
December 2018

Icariside II, a Phosphodiesterase-5 Inhibitor, Attenuates Beta-Amyloid-Induced Cognitive Deficits via BDNF/TrkB/CREB Signaling.

Cell Physiol Biochem 2018 7;49(3):985. Epub 2018 Sep 7.

Department of Pharmacology, Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, China.

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https://www.karger.com/Article/FullText/493232
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http://dx.doi.org/10.1159/000493232DOI Listing
October 2018

Tetrahydroxystilbene Glucoside Produces Neuroprotection against 6-OHDA-Induced Dopamine Neurotoxicity.

Oxid Med Cell Longev 2018 14;2018:7927568. Epub 2018 Jan 14.

Joint International Research Laboratory of Ethnomedicine of Ministry of Education and Key Laboratory of Basic Pharmacology of Ministry of Education, Zunyi Medical University, Zunyi, Guizhou, China.

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http://dx.doi.org/10.1155/2018/7927568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821944PMC
September 2018

Icariside II alleviates oxygen-glucose deprivation and reoxygenation-induced PC12 cell oxidative injury by activating Nrf2/SIRT3 signaling pathway.

Biomed Pharmacother 2018 Jul 24;103:9-17. Epub 2018 Apr 24.

Department of Pharmacology, Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, Guizhou, 563000, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2018.04.005DOI Listing
July 2018

Trilobatin Protects Against Oxidative Injury in Neuronal PC12 Cells Through Regulating Mitochondrial ROS Homeostasis Mediated by AMPK/Nrf2/Sirt3 Signaling Pathway.

Front Mol Neurosci 2018 30;11:267. Epub 2018 Jul 30.

Department of Pharmacology, Key Laboratory of Basic Pharmacology and Joint International Research Laboratory of Ethnomedicine, Ministry of Education, Zunyi Medical University, Zunyi, China.

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http://dx.doi.org/10.3389/fnmol.2018.00267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077207PMC
July 2018

Dual modulation on glial cells by tetrahydroxystilbene glucoside protects against dopamine neuronal loss.

J Neuroinflammation 2018 May 25;15(1):161. Epub 2018 May 25.

Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, Guizhou, China.

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http://dx.doi.org/10.1186/s12974-018-1194-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970496PMC
May 2018

Combination Treatment of Icariin and L-DOPA Against 6-OHDA-Lesioned Dopamine Neurotoxicity.

Front Mol Neurosci 2018 16;11:155. Epub 2018 May 16.

Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, China.

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http://dx.doi.org/10.3389/fnmol.2018.00155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964195PMC
May 2018

Dihydrotanshinone I, a natural product, ameliorates DSS-induced experimental ulcerative colitis in mice.

Toxicol Appl Pharmacol 2018 04 27;344:35-45. Epub 2018 Feb 27.

Key Lab for Pharmacology of Ministry of Education, Department of Pharmacology, Zunyi Medical College, Zunyi, China; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2018.02.018DOI Listing
April 2018

Autophagy plays a protective role in Mn-induced toxicity in PC12 cells.

Toxicology 2018 02 6;394:45-53. Epub 2017 Dec 6.

Joint International Research Laboratory of Ethnomedicine, and Key Laboratory of Basic Pharmacology of Ministry of Education, Zunyi Medical College, Guizhou, China; Department of Environmental Health, School of Public Health, Indiana University, Bloomington, IN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tox.2017.12.001DOI Listing
February 2018

Icariside II, a PDE5 inhibitor from Epimedium brevicornum, promotes neuron-like pheochromocytoma PC12 cell proliferation via activating NO/cGMP/PKG pathway.

Neurochem Int 2018 01 31;112:18-26. Epub 2017 Oct 31.

Department of Pharmacology, Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, Guizhou 563000, China. Electronic address:

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http://dx.doi.org/10.1016/j.neuint.2017.10.015DOI Listing
January 2018

Stimulatory effect of icariin on the proliferation of neural stem cells from rat hippocampus.

BMC Complement Altern Med 2018 Jan 29;18(1):34. Epub 2018 Jan 29.

Joint International Research Laboratory of Ethnomedicine, Zunyi Medical College, Zunyi, Guizhou, China.

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http://dx.doi.org/10.1186/s12906-018-2095-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789743PMC
January 2018

2,3,4',5-tetrahydroxystilbene-2-O-β-D-glucoside exacerbates acetaminophen-induced hepatotoxicity by inducing hepatic expression of CYP2E1, CYP3A4 and CYP1A2.

Sci Rep 2017 11 28;7(1):16511. Epub 2017 Nov 28.

The MOE Key Laboratory for Standardization of Chinese Medicines, Shanghai Key Laboratory of Compound Chinese Medicines and The SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.

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http://dx.doi.org/10.1038/s41598-017-16688-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705655PMC
November 2017

Pharmacological manipulations of autophagy modulate paraquat-induced cytotoxicity in PC12 cells.

Int J Biochem Mol Biol 2017 15;8(2):13-22. Epub 2017 Jun 15.

Joint International Research Laboratory of Ethnomedicine, Key Laboratory of Basic Pharmacology of Ministry of Education, Zunyi Medical UniversityGuizhou, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498847PMC
June 2017

Icariside II Effectively Reduces Spatial Learning and Memory Impairments in Alzheimer's Disease Model Mice Targeting Beta-Amyloid Production.

Front Pharmacol 2017 8;8:106. Epub 2017 Mar 8.

Department of Pharmacology and Key Laboratory of Basic Pharmacology of Ministry of Education, Zunyi Medical University Zunyi, China.

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http://dx.doi.org/10.3389/fphar.2017.00106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340752PMC
March 2017

Icariside II, a novel phosphodiesterase 5 inhibitor, protects against H O -induced PC12 cells death by inhibiting mitochondria-mediated autophagy.

J Cell Mol Med 2017 02 19;21(2):375-386. Epub 2016 Sep 19.

Department of Pharmacology and Key Laboratory of Basic Pharmacology of Ministry of Education, Zunyi Medical University, Guizhou, China.

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http://dx.doi.org/10.1111/jcmm.12971DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264130PMC
February 2017

Puerarin Improves Diabetic Aorta Injury by Inhibiting NADPH Oxidase-Derived Oxidative Stress in STZ-Induced Diabetic Rats.

J Diabetes Res 2016 6;2016:8541520. Epub 2016 Jan 6.

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau.

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http://dx.doi.org/10.1155/2016/8541520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736809PMC
December 2016

Gastrodin ameliorates subacute phase cerebral ischemia‑reperfusion injury by inhibiting inflammation and apoptosis in rats.

Mol Med Rep 2016 Nov 26;14(5):4144-4152. Epub 2016 Sep 26.

Key Laboratory of Basic Pharmacology of Ministry of Education, Department of Pharmacology, Zunyi Medical University, Zunyi, Guizhou 563000, P.R. China.

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http://dx.doi.org/10.3892/mmr.2016.5785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101922PMC
November 2016

Dihydrotanshinone I Attenuates Atherosclerosis in ApoE-Deficient Mice: Role of NOX4/NF-κB Mediated Lectin-Like Oxidized LDL Receptor-1 (LOX-1) of the Endothelium.

Front Pharmacol 2016 8;7:418. Epub 2016 Nov 8.

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau Macao, China.

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http://dx.doi.org/10.3389/fphar.2016.00418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105322PMC
November 2016

Isofuranodiene, the main volatile constituent of wild celery (Smyrnium olusatrum L.), protects d-galactosamin/lipopolysacchride-induced liver injury in rats.

Nat Prod Res 2016 15;30(10):1162-5. Epub 2015 May 15.

a Key Lab for Pharmacology of Ministry of Education, Department of Pharmacology , Zunyi Medical College , Zunyi , P.R. China.

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http://dx.doi.org/10.1080/14786419.2015.1041139DOI Listing
October 2016

Icariin, a major constituent from Epimedium brevicornum, attenuates ibotenic acid-induced excitotoxicity in rat hippocampus.

Behav Brain Res 2016 10 28;313:111-119. Epub 2016 Jun 28.

Department of Pharmacology and Key Laboratory of Basic Pharmacology of Ministry of Education, Zunyi Medical University, Guizhou 563000, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01664328163041
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http://dx.doi.org/10.1016/j.bbr.2016.06.055DOI Listing
October 2016

Cryptotanshinone inhibits TNF-α-induced LOX-1 expression by suppressing reactive oxygen species (ROS) formation in endothelial cells.

Korean J Physiol Pharmacol 2016 Jul 23;20(4):347-55. Epub 2016 Jun 23.

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau 999078, Macao, China.

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http://dx.doi.org/10.4196/kjpp.2016.20.4.347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930903PMC
July 2016

Icariside II protects against cerebral ischemia-reperfusion injury in rats via nuclear factor-κB inhibition and peroxisome proliferator-activated receptor up-regulation.

Neurochem Int 2016 06 3;96:56-61. Epub 2016 Mar 3.

Department of Pharmacology and the Key Laboratory of Basic Pharmacology of Ministry of Education, Zunyi Medical University, Zunyi, 563000, China. Electronic address:

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http://dx.doi.org/10.1016/j.neuint.2016.02.015DOI Listing
June 2016

Sodium Hydrosulfide Attenuates Beta-Amyloid-Induced Cognitive Deficits and Neuroinflammation via Modulation of MAPK/NF-κB Pathway in Rats.

Curr Alzheimer Res 2015 ;12(7):673-83

201 Da Lian Road, Zunyi City, Guizhou Province, 563000, P. R. China.

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April 2016

Icariin induces synoviolin expression through NFE2L1 to protect neurons from ER stress-induced apoptosis.

PLoS One 2015 25;10(3):e0119955. Epub 2015 Mar 25.

Department of Pathology, Northwestern University Feinberg School of Medicine, 303 E. Chicago Ave, Chicago, IL, 60611, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0119955PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373914PMC
March 2016

Icariin attenuates cerebral ischemia-reperfusion injury through inhibition of inflammatory response mediated by NF-κB, PPARα and PPARγ in rats.

Int Immunopharmacol 2016 Jan 8;30:157-162. Epub 2015 Dec 8.

Department of Pharmacology and Key Laboratory of Basic Pharmacology of Ministry of Education, Zunyi Medical University, Zunyi 563000, China. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2015.11.035DOI Listing
January 2016

Effects of corticotrophin-releasing factor receptor 1 antagonists on amyloid-β and behavior in Tg2576 mice.

Psychopharmacology (Berl) 2014 Dec 27;231(24):4711-22. Epub 2014 May 27.

Department of Psychiatry and Behavioral Sciences, Feinberg School Medicine, Northwestern University, 303 E. Chicago Ave, Chicago, IL, 60611, USA,

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http://link.springer.com/10.1007/s00213-014-3629-8
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http://dx.doi.org/10.1007/s00213-014-3629-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233002PMC
December 2014

Alkaloids enriched extract from Dendrobium nobile Lindl. attenuates tau protein hyperphosphorylation and apoptosis induced by lipopolysaccharide in rat brain.

Phytomedicine 2014 Apr 20;21(5):712-6. Epub 2013 Nov 20.

Department of Pharmacology, Zunyi Medical College, Zunyi, Guizhou 563000, China. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2013.10.026DOI Listing
April 2014

Resveratrol protects cortical neurons against microglia-mediated neuroinflammation.

Phytother Res 2013 Mar 14;27(3):344-9. Epub 2012 May 14.

Department of Pharmacology and Key Lab of Basic Pharmacology of Guizhou, Zunyi Medical College, Zunyi, 563099, PR China.

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http://dx.doi.org/10.1002/ptr.4734DOI Listing
March 2013

Osthole attenuates focal inflammatory reaction following permanent middle cerebral artery occlusion in rats.

Biol Pharm Bull 2012 8;35(10):1686-90. Epub 2012 Aug 8.

School of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.

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http://dx.doi.org/10.1248/bpb.b12-00133DOI Listing
March 2013

Adiponectin: a biomarker for rheumatoid arthritis?

Cytokine Growth Factor Rev 2013 Feb 19;24(1):83-9. Epub 2012 Aug 19.

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.

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http://dx.doi.org/10.1016/j.cytogfr.2012.07.004DOI Listing
February 2013

Resveratrol, a neuroprotective supplement for Alzheimer's disease.

Curr Pharm Des 2012 ;18(1):27-33

School of Traditional Chinese Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.

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http://dx.doi.org/10.2174/138161212798919075DOI Listing
May 2012

Role of cinnabar and realgar of WSHFD in protecting against LPS-induced neurotoxicity.

J Ethnopharmacol 2012 Feb 22;139(3):822-8. Epub 2011 Dec 22.

Department of Pharmacology and Key Lab of Basic Pharmacology of Guizhou, Zunyi Medical College, Zunyi, PR China.

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http://dx.doi.org/10.1016/j.jep.2011.12.026DOI Listing
February 2012

[Safety evaluation of realgar-and cinnabar-containing traditional Chinese medicine].

Zhongguo Zhong Yao Za Zhi 2011 Dec;36(24):3402-5

Shanghai University of Traditional Chinese Medicine, Shanghai 20071, China.

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December 2011

[Apoptosis inducing effect of tanshinone II(A) on human nasopharyngeal carcinoma CNE cells].

Zhongguo Zhong Yao Za Zhi 2011 Aug;36(15):2129-33

Pharmacology Department of Guilin Medical College, Guilin 541004, China.

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August 2011

Inhibitory effects of Dendrobium alkaloids on memory impairment induced by lipopolysaccharide in rats.

Planta Med 2011 Jan 17;77(2):117-21. Epub 2010 Aug 17.

Department of Pharmacology, Zunyi Medical College, Zunyi, PR China.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0030-1250235
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http://dx.doi.org/10.1055/s-0030-1250235DOI Listing
January 2011

[Realgar is active ingredient of Angong Niuhuang pill in protection against LPS-induced neuroinflammation].

Zhongguo Zhong Yao Za Zhi 2010 Dec;35(24):3333-8

Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China.

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December 2010