Jin-Hee Ahn

Jin-Hee Ahn

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Jin-Hee Ahn

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Model-based pharmacokinetic and pharmacodynamic analysis for acute effects of a small molecule inhibitor of diacylglycerol acyltransferase-1 in the TallyHo/JngJ polygenic mouse.

Xenobiotica 2019 Jul 5;49(7):823-832. Epub 2018 Sep 5.

e Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology , Chungbuk , Republic of Korea.

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http://dx.doi.org/10.1080/00498254.2018.1496303DOI Listing
July 2019

Effects of lowering inspiratory oxygen fraction during microvascular decompression on postoperative gas exchange: A pre-post study.

PLoS One 2018 14;13(11):e0206371. Epub 2018 Nov 14.

Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0206371PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235305PMC
April 2019

Comparison between linear and focal ablation of complex fractionated atrial electrograms in patients with non-paroxysmal atrial fibrillation: a prospective randomized trial.

Europace 2019 Apr;21(4):598-606

Division of Cardiology, Department of Internal Medicine, Korea University Medical Center, 73 Inchon-ro, Seongbuk-gu, Seoul, Republic of Korea.

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http://dx.doi.org/10.1093/europace/euy313DOI Listing
April 2019

Anti-inflammatory effect of a novel synthetic compound 1-((4-fluorophenyl)thio)isoquinoline in RAW264.7 macrophages and a zebrafish model.

Fish Shellfish Immunol 2019 Apr 25;87:395-400. Epub 2019 Jan 25.

Bio Platform Technology Research Center, Korea Research Institute of Chemical Technology, Daejeon, 34114, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.fsi.2019.01.030DOI Listing
April 2019

The angle range of leg abduction with external hip rotation which can minimize femoral artery and vein overlap in pediatric patients.

Paediatr Anaesth 2019 04 21;29(4):361-367. Epub 2019 Mar 21.

Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1111/pan.13603DOI Listing
April 2019

A Method for Estimating Time-Dependent Corrosion Depth of Carbon and Weathering Steel Using an Atmospheric Corrosion Monitor Sensor.

Sensors (Basel) 2019 Mar 22;19(6). Epub 2019 Mar 22.

Steel Structure Research Group, 100 Songdogwahak-ro, Yeonsu-gu, Incheon 21985, Korea.

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http://dx.doi.org/10.3390/s19061416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471583PMC
March 2019

Improvement of laryngoscopic view by hand-assisted elevation and caudad traction of the shoulder during tracheal intubation in pediatric patients.

Sci Rep 2019 Feb 4;9(1):1174. Epub 2019 Feb 4.

Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1038/s41598-018-37770-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362231PMC
February 2019

ENOblock inhibits the pathology of diet-induced obesity.

Sci Rep 2019 Jan 24;9(1):493. Epub 2019 Jan 24.

New Drug Targets Laboratory, School of Life Sciences, Gwangju Institute of Science and Technology, 1 Oryong-Dong, Buk-Gu, Gwangju, 61005, Republic of Korea.

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http://dx.doi.org/10.1038/s41598-018-36715-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346001PMC
January 2019

Evaluation of Residual Compressive Strength and Behavior of Corrosion-Damaged Carbon Steel Tubular Members.

Materials (Basel) 2018 Jul 20;11(7). Epub 2018 Jul 20.

Department of Civil & Environmental Engineering, Chonnam National University, Yeosu, Jeonnam 59626, Korea.

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http://dx.doi.org/10.3390/ma11071254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073739PMC
July 2018

Elucidating therapeutic molecular targets in premenopausal Asian women with recurrent breast cancers.

NPJ Breast Cancer 2018 26;4:19. Epub 2018 Jul 26.

3Oncology Next-Generation Diagnostics, Novartis Institutes for Biomedical Research, Cambridge, USA.

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http://dx.doi.org/10.1038/s41523-018-0070-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062514PMC
July 2018

How shall we treat early triple-negative breast cancer (TNBC): from the current standard to upcoming immuno-molecular strategies.

ESMO Open 2018 3;3(Suppl 1):e000357. Epub 2018 May 3.

Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Songpa-gu, Seoul, Korea.

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http://dx.doi.org/10.1136/esmoopen-2018-000357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950702PMC
May 2018

Phase III, Randomized, Double-Blind Study Comparing the Efficacy, Safety, and Immunogenicity of SB3 (Trastuzumab Biosimilar) and Reference Trastuzumab in Patients Treated With Neoadjuvant Therapy for Human Epidermal Growth Factor Receptor 2-Positive Early Breast Cancer.

J Clin Oncol 2018 Apr 26;36(10):968-974. Epub 2018 Jan 26.

Xavier Pivot, University Hospital Jean Minjoz, Institut National de la Santé et de la Recherche Médicale 1098, Besançon, France; Igor Bondarenko, State Institution Dnipropetrovsk Medical, Academy of the Ministry of Health of Ukraine, Communal Institution Dnipropetrovsk City Multifield Clinical Hospital No. 4 of Dnipropetrovsk Regional Council, Dnipropetrovsk; Yuriy Vinnyk, Communal Healthcare Institution Kharkiv, Regional Clinical Oncological Center, Kharkiv; Yaroslav Shparyk, Lviv State Oncological Regional Treatment and Diagnostic Center, Lviv, Ukraine; Zbigniew Nowecki, Centrum Onkologii-Instytutim. M. Sklodowskiej Curie; Tomasz Sarosiek, Magodent, Warsaw; Marek Z. Wojtukiewicz, Comprehensive Cancer Center, Medical University, Bialystok, Poland; Mikhail Dvorkin, BHI of Omsk Region, Clinical Oncology Dispensary, Omsk; Ekaterina Trishkina, SBHI Leningrad Regional Oncology Dispensary; Vladimir Moiseyenko, SBHI Saint Petersburg Scientific and Practical Center of Specialized Methods of Medical Help; Vladimir Semiglazov, FSI Scientific and Research Institution of Oncology n.a. N.N. Petrov of Ministry of Healthcare and SD of RF, St Petersburg, Russia; Jin-Hee Ahn, Asan Medical Center; Seock-Ah Im, Seoul National University Hospital, Seoul; Sujeong Song and Jaeyun Lim, Samsung Bioepis, Incheon, Republic of Korea; Sanjoy Chatterjee, Tata Medical Centre, Kolkata, India; and Maximino Bello III, St Luke's Medical Center, Quezon City, Philippines.

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http://dx.doi.org/10.1200/JCO.2017.74.0126DOI Listing
April 2018

A novel anti-melanogenic agent, KDZ-001, inhibits tyrosinase enzymatic activity.

J Dermatol Sci 2018 Feb 20;89(2):165-171. Epub 2017 Nov 20.

Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon 34114, Republic of Korea; Department of Medical Chemistry and Pharmacology, University of Science & Technology, Daejeon, Republic of Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09231811173097
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http://dx.doi.org/10.1016/j.jdermsci.2017.11.004DOI Listing
February 2018

Design, synthesis and biological evaluation of glutamic acid derivatives as anti-oxidant and anti-inflammatory agents.

Bioorg Med Chem Lett 2018 02 7;28(3):529-532. Epub 2017 Nov 7.

Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2017.11.012DOI Listing
February 2018

Gemcitabine and Docetaxel Combination for Advanced Soft Tissue Sarcoma: A Nationwide Retrospective Study.

Cancer Res Treat 2018 Jan 30;50(1):175-182. Epub 2017 Mar 30.

Division of Oncology/Hematology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4143/crt.2016.535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784639PMC
January 2018

Quality of life on TSU-68: Combination of docetaxel and TSU-68, an oral antiangiogenic agent, in patients with metastatic breast cancer previously treated with anthracycline.

Asia Pac J Clin Oncol 2017 Dec 16;13(6):365-371. Epub 2017 Mar 16.

Department of Medical Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1111/ajco.12681DOI Listing
December 2017

Synthesis and biological evaluation of thiazole derivatives as GPR119 agonists.

Bioorg Med Chem Lett 2017 12 20;27(23):5213-5220. Epub 2017 Oct 20.

Department of Medicinal Chemistry and Pharmacology, University of Science & Technology, Daejeon 34113, Republic of Korea; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon 34114, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2017.10.046DOI Listing
December 2017

Expression of TWIST in the first-trimester trophoblast and decidual tissue of women with recurrent pregnancy losses.

Am J Reprod Immunol 2017 08 24;78(2). Epub 2017 Mar 24.

Reproductive Medicine, Department of Obstetrics and Gynecology, Chicago Medical School at Rosalind Franklin University of Medicine and Science, Vernon Hills, IL, USA.

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http://dx.doi.org/10.1111/aji.12670DOI Listing
August 2017

Minimal pneumothorax with dynamic changes in ST segment similar to myocardial infarction.

Am J Emerg Med 2017 Aug 19;35(8):1210.e1-1210.e4. Epub 2017 Apr 19.

Pusan National University Hospital, Department of Emergency Medicine, 179, Gudeok-ro, Seo-gu, Busan 602-739, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.ajem.2017.04.037DOI Listing
August 2017

Design, synthesis, and biological evaluation of aryl N-methoxyamide derivatives as GPR119 agonists.

Bioorg Med Chem Lett 2017 08 13;27(16):3909-3914. Epub 2017 Jun 13.

Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon 305-600, Republic of Korea; Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2017.06.032DOI Listing
August 2017

PPARγ agonists induce adipocyte differentiation by modulating the expression of Lipin-1, which acts as a PPARγ phosphatase.

Int J Biochem Cell Biol 2016 12 22;81(Pt A):57-66. Epub 2016 Oct 22.

Laboratory of Chemical Biology and Genomics, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, Republic of Korea; University of Science and Technology in Korea, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2016.10.018DOI Listing
December 2016

Effect of thoracic epidural analgesia on recovery of bowel function after major upper abdominal surgery.

J Clin Anesth 2016 Nov 13;34:247-52. Epub 2016 May 13.

Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jclinane.2016.04.042DOI Listing
November 2016

Effect of task-specific training on Eph/ephrin expression after stroke.

BMB Rep 2016 Nov;49(11):635-640

Rehabilitation Medicine, Konkuk University School of Medicine; Center for Neuroscience Research, Institute of Biomedical Science and Technology, Konkuk University, Seoul 05029, Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346325PMC
November 2016

Postoperative Radiotherapy After Limb-sparing Surgery for Soft-tissue Sarcomas of the Distal Extremities.

Anticancer Res 2016 09;36(9):4825-31

Department of Orthopedic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

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http://dx.doi.org/10.21873/anticanres.11044DOI Listing
September 2016

Clinical significance of fatty liver disease induced by tamoxifen and toremifene in breast cancer patients.

Breast 2016 Aug 27;28:67-72. Epub 2016 May 27.

Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43 gil, Songpa-gu, Seoul 05505, Republic of Korea.

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http://dx.doi.org/10.1016/j.breast.2016.04.017DOI Listing
August 2016

Anti-inflammatory effect of a selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor via the stimulation of heme oxygenase-1 in LPS-activated mice and J774.1 murine macrophages.

J Pharmacol Sci 2016 Aug 16;131(4):241-50. Epub 2016 Jul 16.

Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, P.O. Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea; Graduate School of New Drug Discovery and Development, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon 305-764, Republic of Korea; Department of Medicinal Chemistry and Pharmacology, University of Science and Technology, 217 Gajeong-ro, Yuseong-gu, Daejeon 305-333, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jphs.2016.07.003DOI Listing
August 2016

Circulating Plasma Biomarkers for TSU-68, an Oral Antiangiogenic Agent, in Patients with Metastatic Breast Cancer.

Cancer Res Treat 2016 Apr 14;48(2):499-507. Epub 2015 Jul 14.

Department of Medical Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4143/crt.2015.089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843716PMC
April 2016

Prognostic tissue biomarker exploration for patients with metastatic renal cell carcinoma receiving vascular endothelial growth factor receptor tyrosine kinase inhibitors.

Tumour Biol 2016 Apr 3;37(4):4919-27. Epub 2015 Nov 3.

Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, Republic of Korea.

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http://dx.doi.org/10.1007/s13277-015-4339-5DOI Listing
April 2016

Pharmacokinetic characterization of 2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone, a novel 11β-hydroxysteroid dehydrogenase type 1 inhibitor in rats.

Arch Pharm Res 2016 Apr 18;39(4):492-498. Epub 2016 Jan 18.

Drug Discovery Platform Technology Group, Korea Research Institute of Chemical Technology, P.O. Box 107, Yuseong-gu, Daejeon, 305-600, Republic of Korea.

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http://dx.doi.org/10.1007/s12272-015-0702-8DOI Listing
April 2016

Cytoplasmic expression of high mobility group B1 (HMGB1) is associated with tumor-infiltrating lymphocytes (TILs) in breast cancer.

Pathol Int 2016 Apr 27;66(4):202-9. Epub 2016 Feb 27.

Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, South Korea.

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http://dx.doi.org/10.1111/pin.12393DOI Listing
April 2016

Small molecules that allosterically inhibit p21-activated kinase activity by binding to the regulatory p21-binding domain.

Exp Mol Med 2016 Apr 29;48:e229. Epub 2016 Apr 29.

Department of Biochemistry, College of Medicine and Medical Research Center, Chungbuk National University, Cheongju, Korea.

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http://dx.doi.org/10.1038/emm.2016.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855275PMC
April 2016

Expression of FOXM1 and related proteins in breast cancer molecular subtypes.

Int J Exp Pathol 2016 04 9;97(2):170-7. Epub 2016 Jun 9.

Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Songpa-gu, Seoul, Korea.

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http://dx.doi.org/10.1111/iep.12187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926053PMC
April 2016

Long-term outcomes of tyrosine kinase inhibitor discontinuation in patients with metastatic renal cell carcinoma.

Cancer Chemother Pharmacol 2016 Feb 21;77(2):339-47. Epub 2015 Dec 21.

Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, Korea.

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http://dx.doi.org/10.1007/s00280-015-2942-1DOI Listing
February 2016

High mobility group B1 and N1 (HMGB1 and HMGN1) are associated with tumor-infiltrating lymphocytes in HER2-positive breast cancers.

Virchows Arch 2015 Dec 7;467(6):701-709. Epub 2015 Oct 7.

Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.

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http://link.springer.com/content/pdf/10.1007%2Fs00428-015-18
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http://link.springer.com/10.1007/s00428-015-1861-1
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http://dx.doi.org/10.1007/s00428-015-1861-1DOI Listing
December 2015

Comparison Between Phenylephrine and Dopamine in Maintaining Cerebral Oxygen Saturation in Thoracic Surgery: A Randomized Controlled Trial.

Medicine (Baltimore) 2015 Dec;94(49):e2212

From the Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-gu, Seoul, Republic of Korea.

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http://dx.doi.org/10.1097/MD.0000000000002212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008502PMC
December 2015

Clinicopathologic Significance of the Intratumoral Heterogeneity of HER2 Gene Amplification in HER2-Positive Breast Cancer Patients Treated With Adjuvant Trastuzumab.

Am J Clin Pathol 2015 Oct;144(4):570-8

From the Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea;

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http://dx.doi.org/10.1309/AJCP51HCGPOPWSCYDOI Listing
October 2015

A phase 1 study of a heterologous prime-boost vaccination involving a truncated HER2 sequence in patients with HER2-expressing breast cancer.

Mol Ther Methods Clin Dev 2015 30;2:15031. Epub 2015 Sep 30.

Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine , Songpa-Gu, Seoul, Korea.

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http://dx.doi.org/10.1038/mtm.2015.31DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588449PMC
October 2015

Tau and PTEN status as predictive markers for response to trastuzumab and paclitaxel in patients with HER2-positive breast cancer.

Tumour Biol 2015 Aug 1;36(8):5865-71. Epub 2015 Mar 1.

Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, Korea.

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http://dx.doi.org/10.1007/s13277-015-3258-9DOI Listing
August 2015

Pulmonary Metastasectomy Could Prolong Overall Survival in Select Cases of Metastatic Urinary Tract Cancer.

Clin Genitourin Cancer 2015 Aug 2;13(4):e297-e304. Epub 2015 May 2.

Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15587673150009
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http://dx.doi.org/10.1016/j.clgc.2015.04.013DOI Listing
August 2015

Prognostic Significance of Tumor-Infiltrating Lymphocytes and the Tertiary Lymphoid Structures in HER2-Positive Breast Cancer Treated With Adjuvant Trastuzumab.

Am J Clin Pathol 2015 Aug;144(2):278-88

From the Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea;

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http://dx.doi.org/10.1309/AJCPIXUYDVZ0RZ3GDOI Listing
August 2015

Discovery and optimization of adamantane carboxylic acid derivatives as potent diacylglycerol acyltransferase 1 inhibitors for the potential treatment of obesity and diabetes.

Eur J Med Chem 2015 Aug 27;101:716-35. Epub 2015 Jun 27.

Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon 305-600, Republic of Korea; Department of Medicinal and Pharmaceutical Chemistry, University of Science and Technology, 305-333, Republic of Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02235234153011
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http://dx.doi.org/10.1016/j.ejmech.2015.06.043DOI Listing
August 2015

Prognostic and predictive value of NanoString-based immune-related gene signatures in a neoadjuvant setting of triple-negative breast cancer: relationship to tumor-infiltrating lymphocytes.

Breast Cancer Res Treat 2015 Jun 26;151(3):619-27. Epub 2015 May 26.

Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, Korea.

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http://link.springer.com/content/pdf/10.1007/s10549-015-3438
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http://link.springer.com/10.1007/s10549-015-3438-8
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http://dx.doi.org/10.1007/s10549-015-3438-8DOI Listing
June 2015

Determination of 2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone by liquid chromatography-tandem mass spectrometry.

J Chromatogr Sci 2014 May-Jun;52(5):406-12. Epub 2013 May 14.

1Drug Discovery Platform Technology Research Group, Korea Research Institute of Chemical Technology (KRICT), Yuseong-gu, Daejeon, 305-600, Korea.

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http://dx.doi.org/10.1093/chromsci/bmt050DOI Listing
May 2015

Vascular endothelial growth factor receptor tyrosine kinase inhibitor (VEGFR-TKI) rechallenge for patients with metastatic renal cell carcinoma after treatment failure using both VEGFR-TKI and mTOR inhibitor.

Cancer Chemother Pharmacol 2015 May 17;75(5):1025-35. Epub 2015 Mar 17.

Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, Korea.

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http://dx.doi.org/10.1007/s00280-015-2725-8DOI Listing
May 2015

Safety and efficacy of a novel, fenestrated aortic arch stent graft with a preloaded catheter for supraaortic arch vessels: an experimental study in Swine.

J Korean Med Sci 2015 Apr 19;30(4):426-34. Epub 2015 Mar 19.

Division of Cardiology, Department of Internal Medicine, College of Medicine, Pusan National University, Medical Research Institute, Pusan National University Hospital, Busan, Korea.

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http://dx.doi.org/10.3346/jkms.2015.30.4.426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366963PMC
April 2015

Correlations between molecular subtypes and pathologic response patterns of breast cancers after neoadjuvant chemotherapy.

Ann Surg Oncol 2015 Feb 6;22(2):392-400. Epub 2014 Sep 6.

Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.

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http://dx.doi.org/10.1245/s10434-014-4054-2DOI Listing
February 2015

Comparable efficacy of silk fibroin with the collagen membranes for guided bone regeneration in rat calvarial defects.

J Adv Prosthodont 2014 Dec 17;6(6):539-46. Epub 2014 Dec 17.

Department of Prosthodontics, Hallym University School of Medicine, Hallym University Sacred Heart Hospital, Anyang, Republic of Korea.

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http://dx.doi.org/10.4047/jap.2014.6.6.539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279054PMC
December 2014

Prognostic significance of the ratio of absolute neutrophil to lymphocyte counts for breast cancer patients with ER/PR-positivity and HER2-negativity in neoadjuvant setting.

Tumour Biol 2014 Oct 2;35(10):9823-30. Epub 2014 Jul 2.

Department of Pathology, Ajou University School of Medicine, Suwon, South Korea.

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http://dx.doi.org/10.1007/s13277-014-2282-5DOI Listing
October 2014

Synthesis and biological evaluation of thienopyrimidine derivatives as GPR119 agonists.

Bioorg Med Chem Lett 2014 Sep 28;24(17):4281-5. Epub 2014 Jul 28.

Drug Discovery Division, Korea Research Institute of Chemical Technology, Republic of Korea; Department of Medicinal and Pharmaceutical Chemistry, University of Science and Technology, 305-333, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2014.07.020DOI Listing
September 2014

Active surveillance for metastatic or recurrent renal cell carcinoma.

J Cancer Res Clin Oncol 2014 Aug 22;140(8):1421-8. Epub 2014 Apr 22.

Department of Oncology, Asan Medical Centre, University of Ulsan College of Medicine, 88 Olympic-Ro 43-Gil, Songpa-gu, Seoul, 138-736, Korea.

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http://dx.doi.org/10.1007/s00432-014-1680-9DOI Listing
August 2014

MET expression is associated with disease-specific survival in breast cancer patients in the neoadjuvant setting.

Pathol Res Pract 2014 Aug 18;210(8):494-500. Epub 2014 Apr 18.

Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 138-736, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.prp.2014.04.002DOI Listing
August 2014

Anti-obesity effects of KR-66195, a synthetic DPP-IV inhibitor, in diet-induced obese mice and obese-diabetic ob/ob mice.

Metabolism 2014 Jun 25;63(6):793-9. Epub 2014 Feb 25.

Department of Internal Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2014.02.011DOI Listing
June 2014

Two histopathologically different diseases: hormone receptor-positive and hormone receptor-negative tumors in HER2-positive breast cancer.

Breast Cancer Res Treat 2014 Jun 13;145(3):615-23. Epub 2014 May 13.

Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, South Korea.

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http://dx.doi.org/10.1007/s10549-014-2983-xDOI Listing
June 2014

Preclinical pharmacokinetic characterization of 2-(4-(4-(5-(2-phenyl-5-(trifluoromethyl)oxazole-4-carboxamido)-1H-benzo[d]imidazol-2-yl)phenyl)cyclohexyl) acetic acid, a novel DGAT-1 inhibitor.

Xenobiotica 2014 May 23;44(5):465-71. Epub 2013 Oct 23.

Drug Discovery Platform Technology Research Group, Division of Bio-organic Science, Korea Research Institute of Chemical Technology , Daejeon , Republic of Korea and.

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http://dx.doi.org/10.3109/00498254.2013.847218DOI Listing
May 2014

Low prognostic implication of fibroblast growth factor family activation in triple-negative breast cancer subsets.

Ann Surg Oncol 2014 May 3;21(5):1561-8. Epub 2014 Jan 3.

Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea,

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http://dx.doi.org/10.1245/s10434-013-3456-xDOI Listing
May 2014

Transport characteristics and transporter-based drug-drug interactions of TM-25659, a novel TAZ modulator.

Biopharm Drug Dispos 2014 Apr 18;35(3):183-94. Epub 2013 Dec 18.

College of Pharmacy, Dankook University, Cheonan, Korea.

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http://dx.doi.org/10.1002/bdd.1883DOI Listing
April 2014

A novel 11β-HSD1 inhibitor improves diabesity and osteoblast differentiation.

J Mol Endocrinol 2014 Apr 6;52(2):191-202. Epub 2014 Mar 6.

Division of Drug Discovery Research, Korea Research Institute of Chemical Technology, PO Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea Division of Life and Pharmaceutical Sciences and Center for Cell Signaling and Drug Discovery Research, College of Pharmacy, Ewha Woman's University, Sedaemoon-gu, Seoul 120-750, Republic of Korea Laboratory of Translational Therapeutics, Korea Research Institute of Chemical Technology, Pharmacology Research Center, PO Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea Department of Toxicology, College of Pharmacy, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon 305-764, Republic of Korea Department of Medicinal and Pharmaceutical Chemistry, University of Science and Technology, 217 Gajeong-ro, Yuseong-gu, Daejeon 305-333, Republic of Korea.

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http://dx.doi.org/10.1530/JME-13-0177DOI Listing
April 2014

KR-62980 suppresses lipid metabolism through inhibition of cytosolic NADP isocitrate dehydrogenase in zebrafish.

Zebrafish 2014 Apr 3;11(2):122-8. Epub 2014 Mar 3.

Drug Discovery Platform Technology Team, Korea Research Institute of Chemical Technology , Daejeon, Republic of Korea.

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http://dx.doi.org/10.1089/zeb.2013.0919DOI Listing
April 2014

Determination of a novel diacylglycerol acyltransferase 1 inhibitor, 2-[4-(4-{5-[2-phenyl-5-(trifluoromethyl) oxazole-4-carboxamido]-1H-benzo[d]imidazol-2-yl} phenyl) cyclohexyl] acetic acid (KR-69232) in rat plasma using liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study.

Biomed Chromatogr 2014 Mar 14;28(3):324-6. Epub 2013 Oct 14.

Drug Discovery Platform Technology Group, Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea; College of Pharmacy, Chungbuk National University, Cheongju, Republic of Korea.

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http://doi.wiley.com/10.1002/bmc.3053
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http://dx.doi.org/10.1002/bmc.3053DOI Listing
March 2014

Multicenter phase II study of everolimus in patients with metastatic or recurrent bone and soft-tissue sarcomas after failure of anthracycline and ifosfamide.

Invest New Drugs 2013 Dec 14;31(6):1602-8. Epub 2013 Sep 14.

Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, South Korea, 138-736.

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http://dx.doi.org/10.1007/s10637-013-0028-7DOI Listing
December 2013

Anti-diabetic and anti-inflammatory effect of a novel selective 11β-HSD1 inhibitor in the diet-induced obese mice.

Eur J Pharmacol 2013 Dec 14;721(1-3):70-9. Epub 2013 Oct 14.

Division of Drug Discovery Research, Korea Research Institute of Chemical Technology, P.O.Box 107, Yuseong-gu, Daejeon 305-600, Korea; Department of Toxicology, College of Pharmacy, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon 305-764, Korea.

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http://dx.doi.org/10.1016/j.ejphar.2013.09.052DOI Listing
December 2013

Prognostic factors in patients with proven or possible vasospastic angina who underwent coronary spasm provocation test.

Int J Cardiol 2013 Oct 13;168(3):3044-5. Epub 2013 May 13.

Department of Cardiology, Pusan National University Hospital, Busan, South Korea.

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http://dx.doi.org/10.1016/j.ijcard.2013.04.130DOI Listing
October 2013

Chemotherapy-induced amenorrhea, menopause-specific quality of life, and endocrine profiles in premenopausal women with breast cancer who received adjuvant anthracycline-based chemotherapy: a prospective cohort study.

Cancer Chemother Pharmacol 2013 Sep 11;72(3):565-75. Epub 2013 Jul 11.

Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro, Songpa-gu, Seoul, Korea.

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http://dx.doi.org/10.1007/s00280-013-2227-5DOI Listing
September 2013

Visualization and isolation of Langerhans islets by a fluorescent probe PiY.

Angew Chem Int Ed Engl 2013 Aug 28;52(33):8557-60. Epub 2013 May 28.

Singapore Bioimaging Consortium, Agency for Science, Technology and Research, 138667, Singapore, Singapore.

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http://dx.doi.org/10.1002/anie.201302149DOI Listing
August 2013

Synthesis and biological evaluation of aminobenzimidazole derivatives with a phenylcyclohexyl acetic acid group as anti-obesity and anti-diabetic agents.

Bioorg Med Chem Lett 2013 Aug 4;23(16):4713-8. Epub 2013 Jun 4.

Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon 305-600, Republic of Korea.

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http://dx.doi.org/10.1016/j.bmcl.2013.05.081DOI Listing
August 2013

Clinical features and outcome of leptomeningeal metastasis in patients with breast cancer: a single center experience.

Cancer Chemother Pharmacol 2013 Jul 14;72(1):201-7. Epub 2013 May 14.

Departments of Oncology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, Korea.

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http://dx.doi.org/10.1007/s00280-013-2185-yDOI Listing
July 2013

Expression of Lewis X is associated with poor prognosis in triple-negative breast cancer.

Am J Clin Pathol 2013 Jun;139(6):746-53

Dept of Pathology, University of Ulsan College of Medicine, Asan Medical Center, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 138-736, Korea.

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http://dx.doi.org/10.1309/AJCP2E6QNDIDPTTCDOI Listing
June 2013

Tumor-associated lymphocytes predict response to neoadjuvant chemotherapy in breast cancer patients.

J Breast Cancer 2013 Mar 31;16(1):32-9. Epub 2013 Mar 31.

Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4048/jbc.2013.16.1.32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625767PMC
March 2013