Publications by authors named "Jin-Chang Wang"

3 Publications

  • Page 1 of 1

Full-Endoscopic Oblique Lateral Lumbar Interbody Fusion: A Technical Note With 1-Year Follow-Up.

Int J Spine Surg 2021 Jun 7;15(3):504-513. Epub 2021 May 7.

Desert Institute for Spine Care, Phoenix, Arizona; Executive Director International Intradiscal Therapy Society, Phoenix, Arizona.

Background: Oblique lateral lumbar interbody fusion (OLLIF) is a minimally invasive lumbar interbody fusion procedure using a bullet-shaped polyetheretherketone (PEEK) nonexpandable fusion cage modified to diminish risk to the exiting nerve root during posterolateral implantation through the Kambin safe zone under fluoroscopic guidance. The objective of this study was to present feasibility of this procedure and 1-year clinical outcome data.

Methods: The authors present a prospective cohort study of 20 patients who underwent fluoroscopy-guided and full-endoscopic OLLIF in 22 segments allowing protection of the exiting nerve root from January 2018 to March 2019. The foraminoplasty, discectomy, endplate preparation, placement of bone graft and insertion of the fusion cage was done under continuous full-endoscopic visualization. The OLLIF fusion was backed up with bilateral percutaneous posterior supplemental pedicle screw fixation. Primary clinical outcome measures were the visual analog scale (VAS) of low back and leg pain, and Oswestry disability index (ODI) at 1 week, 3 months, 6 months, and 1 year after the operation. At final follow-up, the Macnab score was also evaluated. Secondary outcome measures were computed tomography (CT) assessment fusion using the Mannion classification of spinal fusion and adverse events related to the device as well as magnetic resonance imaging (MRI) assessment of nerve root decompression.

Results: All patients had significant relief of low back pain and leg pain, by VAS and ODI scores that improved significantly ( < .01). There were no complications. Postoperative lumbar MRI of all patients showed sufficient direct nerve decompression. At 1-year follow-up, excellent Macnab outcomes were obtained 13 patients, good in six, and fair in one. Impaired sensation and muscle strength of the involved nerve root significantly recovered in all but 2 patients ( < .05). According to the Mannion CT-based classification of spinal fusion, CT showed complete interbody fusion achieved in all 22 segments.

Conclusions: Full-endoscopic OLLIF is a safe, effective, minimally invasive, economical, practical, and widely applicable minimally invasive interbody fusion technique in the lumbar spine.

Level Of Evidence: 3.
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June 2021

Relationship between granulomatous lobular mastitis and methylene tetrahydrofolate reductase gene polymorphism.

World J Clin Cases 2020 Sep;8(18):4017-4021

Department of Breast, The First People's Hospital of Kunming, Kunming 650031, Yunnan Province, China.

Background: Variations in the methylene tetrahydrofolate reductase () gene have been reported as risk factors for numerous conditions, including cardiovascular disease, thrombophilia, stroke, hypertension and pregnancy-related complications. Moreover, it was reported there is an association between breast cancer and mutations in -C677T. However, whether there is an association between gene polymorphism and granulomatous lobular mastitis or not has been rarely investigated.

Aim: To analyze the association between gene polymorphism and granulomatous lobular mastitis.

Methods: Fifty-one patients with granulomatous lobular mastitis admitted to The First Hospital of Kunming were selected as study samples. Their hospitalization time ranged from February 2018 to February 2019. The 51 patients were included in the experimental group, and another 51 women who underwent physical examination at The First Hospital of Kunming in the same period were included in the control group. Deoxyribonucleic acid and R genetic polymorphism testing were performed in each group. The association between gene polymorphism and granulomatous lobular mastitis was observed.

Results: There were significant differences in genotype frequency and allele frequency of C/C and C/T between the experimental group and the control group (all < 0.05). However, there was no significant difference in frequency of T/T genotype between the two groups ( > 0.05). In addition, there was no significant difference in genotype frequency and allele frequency of A/A, A/C and C/C between the two groups ( > 0.05).

Conclusion: gene C677T locus polymorphism is closely related to granulomatous lobular mastitis.
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September 2020

[Research on the combustion mechanism of asphalt and the composition of harmful gas based on infrared spectral analysis].

Guang Pu Xue Yu Guang Pu Fen Xi 2012 Aug;32(8):2089-94

College of Civil Engineering and Architecture, Zhejiang University, Hangzhou 310027, China.

By using the Rosemount gas analyzer and the test platform of fixed bed built by carbon furnace, the harmful gaseous compositions and the release rules of asphalt and mortar under high temperature rate were analyzed quantitatively based on infrared spectral analysis technology. The results indicated that the combustion process of the asphalt and mortar can be approximately divided into two stages stage of primary volatile combustion, and stage of secondary volatile release combined with fixed carbon combustion in isothermal condition with high heating rate. The major gaseous products are CO2, CO, NO, NO2 and SO2. the volatile content is one of the key factors affecting the release rules of gaseous combustion products in asphalt, and reducing the volatile content in asphalt materials can effectively reduce the generation of gaseous combustion products, especially CO.
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August 2012