Jin Y Jin

Jin Y Jin

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Jin Y Jin

Jin Y Jin

Publications by authors named "Jin Y Jin"

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35Publications

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Pharmacokinetics of polatuzumab vedotin in combination with R/G-CHP in patients with B-cell non-Hodgkin lymphoma.

Cancer Chemother Pharmacol 2020 May 28;85(5):831-842. Epub 2020 Mar 28.

Department of Clinical Pharmacology Oncology, Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA.

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http://dx.doi.org/10.1007/s00280-020-04054-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188703PMC
May 2020

Progress and Opportunities to Advance Clinical Cancer Therapeutics Using Tumor Dynamic Models.

Clin Cancer Res 2020 Apr 23;26(8):1787-1795. Epub 2019 Dec 23.

Genentech-Roche, South San Francisco, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-0287DOI Listing
April 2020

Analysis of Longitudinal-Ordered Categorical Data for Muscle Spasm Adverse Event of Vismodegib: Comparison Between Different Pharmacometric Models.

CPT Pharmacometrics Syst Pharmacol 2020 Feb 30;9(2):96-105. Epub 2020 Jan 30.

Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA.

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http://dx.doi.org/10.1002/psp4.12487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020275PMC
February 2020

Tumor Time-Course Predicts Overall Survival in Non-Small Cell Lung Cancer Patients Treated with Atezolizumab: Dependency on Follow-Up Time.

CPT Pharmacometrics Syst Pharmacol 2020 Feb 28;9(2):115-123. Epub 2020 Jan 28.

Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1002/psp4.12489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020300PMC
February 2020

Toward Progress in Quantitative Translational Medicine: A Call to Action.

Clin Pharmacol Ther 2020 Jan 21;107(1):85-88. Epub 2019 Nov 21.

GSK, Collegeville, Pennsylvania, USA.

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http://dx.doi.org/10.1002/cpt.1687DOI Listing
January 2020

Proceedings of a Workshop: US Food and Drug Administration-International Society of Pharmacometrics Model-Informed Drug Development in Oncology.

Clin Pharmacol Ther 2019 07 5;106(1):81-83. Epub 2019 Apr 5.

US Food and Drug Administration, Silver Spring, Maryland, USA.

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http://dx.doi.org/10.1002/cpt.1421DOI Listing
July 2019

Challenges and Opportunities in Dose Finding in Oncology and Immuno-oncology.

Clin Transl Sci 2018 07 1;11(4):345-351. Epub 2018 Feb 1.

Quantitative Clinical Pharmacology, Takeda International Inc., Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1111/cts.12540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039198PMC
July 2018

A Pharmacometric Analysis of Patient-Reported Outcomes in Breast Cancer Patients Through Item Response Theory.

Pharm Res 2018 Apr 19;35(6):122. Epub 2018 Apr 19.

Department of Pharmaceutical Biosciences, Uppsala University, Box 591, SE-75124, Uppsala, Sweden.

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http://dx.doi.org/10.1007/s11095-018-2403-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908825PMC
April 2018

Platform model describing pharmacokinetic properties of vc-MMAE antibody-drug conjugates.

J Pharmacokinet Pharmacodyn 2017 Dec 16;44(6):537-548. Epub 2017 Sep 16.

Clinical Pharmacology, Genentech Inc, 1 DNA Way, South San Francisco, CA, 94080, USA.

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http://link.springer.com/10.1007/s10928-017-9544-y
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http://dx.doi.org/10.1007/s10928-017-9544-yDOI Listing
December 2017

Population pharmacokinetics and dosing implications for cobimetinib in patients with solid tumors.

Cancer Chemother Pharmacol 2015 Nov 13;76(5):917-24. Epub 2015 Sep 13.

Clinical Pharmacology, Genentech Inc, South San Francisco, CA, USA.

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http://dx.doi.org/10.1007/s00280-015-2862-0DOI Listing
November 2015

The American Conference on Pharmacometrics 2015 (ACoP6).

J Pharmacokinet Pharmacodyn 2015 Oct;42 Suppl 1:1-2

University at Buffalo, SUNY, 431 Kapoor Hall, Buffalo, NY, 14214, USA.

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http://dx.doi.org/10.1007/s10928-015-9431-3DOI Listing
October 2015

The use of betaine HCl to enhance dasatinib absorption in healthy volunteers with rabeprazole-induced hypochlorhydria.

AAPS J 2014 Nov 2;16(6):1358-65. Epub 2014 Oct 2.

Department of Bioengineering and Therapeutic Sciences, University of California, 533 Parnassus Avenue, Room U-68, San Francisco, California, 94143-0912, USA.

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http://dx.doi.org/10.1208/s12248-014-9673-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389759PMC
November 2014

Impact of food and the proton pump inhibitor rabeprazole on the pharmacokinetics of GDC-0941 in healthy volunteers: bench to bedside investigation of pH-dependent solubility.

Mol Pharm 2013 Nov 24;10(11):4074-81. Epub 2013 Oct 24.

Small Molecule Clinical Pharmacology, ‡Small Molecule Pharmaceutical Sciences, §Drug Metabolism and Pharmacokinetics, ∥Clinical Project Management, and ⊥Early Clinical Development, Genentech Research and Early Development , 1 DNA Way, South San Francisco, California 94080, United States.

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http://dx.doi.org/10.1021/mp4005595DOI Listing
November 2013

A physiologically based pharmacokinetic (PBPK) approach to evaluate pharmacokinetics in patients with cancer.

Biopharm Drug Dispos 2013 Apr 26;34(3):141-54. Epub 2013 Feb 26.

Department of Clinical Pharmacology, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1002/bdd.1830DOI Listing
April 2013

Application of IVIVE and PBPK modeling in prospective prediction of clinical pharmacokinetics: strategy and approach during the drug discovery phase with four case studies.

Biopharm Drug Dispos 2012 Mar 24;33(2):85-98. Epub 2012 Jan 24.

Department of Drug Metabolism and Pharmacokinetics, Genentech Inc., South San Francisco, USA.

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http://dx.doi.org/10.1002/bdd.1769DOI Listing
March 2012

Absorption barriers in the rat intestinal mucosa: 2. Application of physiologically based mathematical models to quantify mechanisms of drug permeation and metabolism.

J Pharm Sci 2010 Feb;99(2):999-1015

Department of Pharmaceutical Chemistry, University of Kansas, Lawrence, Kansas 45429, USA.

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http://dx.doi.org/10.1002/jps.21965DOI Listing
February 2010

Pharmacodynamics of glucose regulation by methylprednisolone. II. normal rats.

Biopharm Drug Dispos 2009 Jan;30(1):35-48

Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, State University of New York, Buffalo, NY 14260, USA.

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http://doi.wiley.com/10.1002/bdd.642
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http://dx.doi.org/10.1002/bdd.642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712293PMC
January 2009

Pharmacodynamics of glucose regulation by methylprednisolone. I. Adrenalectomized rats.

Biopharm Drug Dispos 2009 Jan;30(1):21-34

Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, State University of New York, Buffalo, NY 14260, USA.

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http://dx.doi.org/10.1002/bdd.643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712292PMC
January 2009

Pharmacogenomic responses of rat liver to methylprednisolone: an approach to mining a rich microarray time series.

AAPS J 2005 Aug 18;7(1):E156-94. Epub 2005 Aug 18.

Department of Pharmaceutical Sciences, State University of New York at Buffalo, Buffalo, NY 14260, USA.

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http://dx.doi.org/10.1208/aapsj070117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607485PMC
August 2005

Temporal profiling of the transcriptional basis for the development of corticosteroid-induced insulin resistance in rat muscle.

J Endocrinol 2005 Jan;184(1):219-32

Department of Biological Sciences, State University of New York at Buffalo, Buffalo, NY 14260, USA.

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http://dx.doi.org/10.1677/joe.1.05953DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2574435PMC
January 2005

Receptor/gene-mediated pharmacodynamic effects of methylprednisolone on phosphoenolpyruvate carboxykinase regulation in rat liver.

J Pharmacol Exp Ther 2004 Apr 13;309(1):328-39. Epub 2004 Jan 13.

Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, State University of New York at Buffalo, Buffalo, NY, USA.

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http://dx.doi.org/10.1124/jpet.103.061515DOI Listing
April 2004

Modeling of corticosteroid pharmacogenomics in rat liver using gene microarrays.

J Pharmacol Exp Ther 2003 Oct 13;307(1):93-109. Epub 2003 Jun 13.

Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, 565 Hochstetter Hall, State University of New York at Buffalo, 14260, USA.

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http://dx.doi.org/10.1124/jpet.103.053256DOI Listing
October 2003