Jin Hee Ahn

Jin Hee Ahn

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Jin Hee Ahn

Publications by authors named "Jin Hee Ahn"

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Protective effect of a novel selective 11β-HSD1 inhibitor on eye ischemia-reperfusion induced glaucoma.

Biochem Pharmacol 2019 Nov 5;169:113632. Epub 2019 Sep 5.

Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, P.O. Box 107, Yuseong-gu, Daejeon 34114, Republic of Korea; Graduate School of New Drug Discovery and Development, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon 34134, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2019.113632DOI Listing
November 2019

Identification of new aryl hydrocarbon receptor (AhR) antagonists using a zebrafish model.

Bioorg Med Chem 2019 Oct 18;27(19):115014. Epub 2019 Jul 18.

Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2019.07.030DOI Listing
October 2019

Is asymptomatic surveillance beneficial after standard treatment? A 10-year survival analysis of recurrent BC patients by detection method of recurrence.

Breast J 2019 Sep 17. Epub 2019 Sep 17.

Department of Surgery, Division of breast surgery, College of Medicine, Asan Medical Center, University of Ulsan, Seoul, Korea.

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http://dx.doi.org/10.1111/tbj.13603DOI Listing
September 2019

Dopamine neuron induction and the neuroprotective effects of thyroid hormone derivatives.

Sci Rep 2019 Sep 20;9(1):13659. Epub 2019 Sep 20.

Hanyang Biomedical Research Institute, Hanyang University, Seoul, 04763, Korea.

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http://dx.doi.org/10.1038/s41598-019-49876-6DOI Listing
September 2019

Clinical outcomes of angiosarcoma: a single institution experience.

Cancer Commun (Lond) 2019 Aug 6;39(1):44. Epub 2019 Aug 6.

Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea.

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http://dx.doi.org/10.1186/s40880-019-0389-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685159PMC
August 2019

Model-based pharmacokinetic and pharmacodynamic analysis for acute effects of a small molecule inhibitor of diacylglycerol acyltransferase-1 in the TallyHo/JngJ polygenic mouse.

Xenobiotica 2019 Jul 5;49(7):823-832. Epub 2018 Sep 5.

e Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology , Chungbuk , Republic of Korea.

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http://dx.doi.org/10.1080/00498254.2018.1496303DOI Listing
July 2019

Clinical Implication of HER2 Status in Hormone Receptor-Positive Mucinous Breast Cancer.

Ann Surg Oncol 2019 Jul 11;26(7):2166-2174. Epub 2019 Apr 11.

Department of Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.

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http://dx.doi.org/10.1245/s10434-019-07332-9DOI Listing
July 2019

Effects of neuromuscular blockade reversal on bispectral index and frontal electromyogram during steady-state desflurane anesthesia: a randomized trial.

Sci Rep 2019 Jul 19;9(1):10486. Epub 2019 Jul 19.

Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1038/s41598-019-47047-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642209PMC
July 2019

Total Intravenous Anesthesia Maintained the Degree of Pre-Existing Mitral Regurgitation Better than Isoflurane Anesthesia in Cardiac Surgery: A Randomized Controlled Trial.

J Clin Med 2019 Jul 25;8(8). Epub 2019 Jul 25.

Department of Anesthesiology and Pain Medicine, College of Medicine, Kyung Hee, University, Seoul 02447, Korea.

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http://dx.doi.org/10.3390/jcm8081104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723839PMC
July 2019

Characteristics of metastatic brachial plexopathy in patients with breast cancer.

Support Care Cancer 2019 Jul 30. Epub 2019 Jul 30.

Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.

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http://dx.doi.org/10.1007/s00520-019-04997-6DOI Listing
July 2019

Intrinsic Prognostic Impact of Tumor-infiltrating Lymphocytes in Systemically Untreated Patients With Early-stage Triple-negative Breast Cancer.

Anticancer Res 2019 Jun;39(6):3111-3119

Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

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http://dx.doi.org/10.21873/anticanres.13447DOI Listing
June 2019

Effects of lowering inspiratory oxygen fraction during microvascular decompression on postoperative gas exchange: A pre-post study.

PLoS One 2018 14;13(11):e0206371. Epub 2018 Nov 14.

Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0206371PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235305PMC
April 2019

Comparison between linear and focal ablation of complex fractionated atrial electrograms in patients with non-paroxysmal atrial fibrillation: a prospective randomized trial.

Europace 2019 Apr;21(4):598-606

Division of Cardiology, Department of Internal Medicine, Korea University Medical Center, 73 Inchon-ro, Seongbuk-gu, Seoul, Republic of Korea.

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http://dx.doi.org/10.1093/europace/euy313DOI Listing
April 2019

Anti-inflammatory effect of a novel synthetic compound 1-((4-fluorophenyl)thio)isoquinoline in RAW264.7 macrophages and a zebrafish model.

Fish Shellfish Immunol 2019 Apr 25;87:395-400. Epub 2019 Jan 25.

Bio Platform Technology Research Center, Korea Research Institute of Chemical Technology, Daejeon, 34114, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.fsi.2019.01.030DOI Listing
April 2019

The angle range of leg abduction with external hip rotation which can minimize femoral artery and vein overlap in pediatric patients.

Paediatr Anaesth 2019 04 21;29(4):361-367. Epub 2019 Mar 21.

Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1111/pan.13603DOI Listing
April 2019

A Method for Estimating Time-Dependent Corrosion Depth of Carbon and Weathering Steel Using an Atmospheric Corrosion Monitor Sensor.

Sensors (Basel) 2019 Mar 22;19(6). Epub 2019 Mar 22.

Steel Structure Research Group, 100 Songdogwahak-ro, Yeonsu-gu, Incheon 21985, Korea.

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http://dx.doi.org/10.3390/s19061416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471583PMC
March 2019

Improvement of laryngoscopic view by hand-assisted elevation and caudad traction of the shoulder during tracheal intubation in pediatric patients.

Sci Rep 2019 Feb 4;9(1):1174. Epub 2019 Feb 4.

Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1038/s41598-018-37770-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362231PMC
February 2019

ENOblock inhibits the pathology of diet-induced obesity.

Sci Rep 2019 Jan 24;9(1):493. Epub 2019 Jan 24.

New Drug Targets Laboratory, School of Life Sciences, Gwangju Institute of Science and Technology, 1 Oryong-Dong, Buk-Gu, Gwangju, 61005, Republic of Korea.

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http://dx.doi.org/10.1038/s41598-018-36715-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346001PMC
January 2019

Evaluation of Residual Compressive Strength and Behavior of Corrosion-Damaged Carbon Steel Tubular Members.

Materials (Basel) 2018 Jul 20;11(7). Epub 2018 Jul 20.

Department of Civil & Environmental Engineering, Chonnam National University, Yeosu, Jeonnam 59626, Korea.

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http://dx.doi.org/10.3390/ma11071254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073739PMC
July 2018

Elucidating therapeutic molecular targets in premenopausal Asian women with recurrent breast cancers.

NPJ Breast Cancer 2018 26;4:19. Epub 2018 Jul 26.

3Oncology Next-Generation Diagnostics, Novartis Institutes for Biomedical Research, Cambridge, USA.

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http://dx.doi.org/10.1038/s41523-018-0070-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062514PMC
July 2018

How shall we treat early triple-negative breast cancer (TNBC): from the current standard to upcoming immuno-molecular strategies.

ESMO Open 2018 3;3(Suppl 1):e000357. Epub 2018 May 3.

Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Songpa-gu, Seoul, Korea.

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http://dx.doi.org/10.1136/esmoopen-2018-000357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950702PMC
May 2018

Phase III, Randomized, Double-Blind Study Comparing the Efficacy, Safety, and Immunogenicity of SB3 (Trastuzumab Biosimilar) and Reference Trastuzumab in Patients Treated With Neoadjuvant Therapy for Human Epidermal Growth Factor Receptor 2-Positive Early Breast Cancer.

J Clin Oncol 2018 04 26;36(10):968-974. Epub 2018 Jan 26.

Xavier Pivot, University Hospital Jean Minjoz, Institut National de la Santé et de la Recherche Médicale 1098, Besançon, France; Igor Bondarenko, State Institution Dnipropetrovsk Medical, Academy of the Ministry of Health of Ukraine, Communal Institution Dnipropetrovsk City Multifield Clinical Hospital No. 4 of Dnipropetrovsk Regional Council, Dnipropetrovsk; Yuriy Vinnyk, Communal Healthcare Institution Kharkiv, Regional Clinical Oncological Center, Kharkiv; Yaroslav Shparyk, Lviv State Oncological Regional Treatment and Diagnostic Center, Lviv, Ukraine; Zbigniew Nowecki, Centrum Onkologii-Instytutim. M. Sklodowskiej Curie; Tomasz Sarosiek, Magodent, Warsaw; Marek Z. Wojtukiewicz, Comprehensive Cancer Center, Medical University, Bialystok, Poland; Mikhail Dvorkin, BHI of Omsk Region, Clinical Oncology Dispensary, Omsk; Ekaterina Trishkina, SBHI Leningrad Regional Oncology Dispensary; Vladimir Moiseyenko, SBHI Saint Petersburg Scientific and Practical Center of Specialized Methods of Medical Help; Vladimir Semiglazov, FSI Scientific and Research Institution of Oncology n.a. N.N. Petrov of Ministry of Healthcare and SD of RF, St Petersburg, Russia; Jin-Hee Ahn, Asan Medical Center; Seock-Ah Im, Seoul National University Hospital, Seoul; Sujeong Song and Jaeyun Lim, Samsung Bioepis, Incheon, Republic of Korea; Sanjoy Chatterjee, Tata Medical Centre, Kolkata, India; and Maximino Bello III, St Luke's Medical Center, Quezon City, Philippines.

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http://dx.doi.org/10.1200/JCO.2017.74.0126DOI Listing
April 2018

A novel anti-melanogenic agent, KDZ-001, inhibits tyrosinase enzymatic activity.

J Dermatol Sci 2018 Feb 20;89(2):165-171. Epub 2017 Nov 20.

Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon 34114, Republic of Korea; Department of Medical Chemistry and Pharmacology, University of Science & Technology, Daejeon, Republic of Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09231811173097
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http://dx.doi.org/10.1016/j.jdermsci.2017.11.004DOI Listing
February 2018

Design, synthesis and biological evaluation of glutamic acid derivatives as anti-oxidant and anti-inflammatory agents.

Bioorg Med Chem Lett 2018 02 7;28(3):529-532. Epub 2017 Nov 7.

Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2017.11.012DOI Listing
February 2018

Gemcitabine and Docetaxel Combination for Advanced Soft Tissue Sarcoma: A Nationwide Retrospective Study.

Cancer Res Treat 2018 Jan 30;50(1):175-182. Epub 2017 Mar 30.

Division of Oncology/Hematology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4143/crt.2016.535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784639PMC
January 2018

Quality of life on TSU-68: Combination of docetaxel and TSU-68, an oral antiangiogenic agent, in patients with metastatic breast cancer previously treated with anthracycline.

Asia Pac J Clin Oncol 2017 Dec 16;13(6):365-371. Epub 2017 Mar 16.

Department of Medical Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1111/ajco.12681DOI Listing
December 2017

Synthesis and biological evaluation of thiazole derivatives as GPR119 agonists.

Bioorg Med Chem Lett 2017 12 20;27(23):5213-5220. Epub 2017 Oct 20.

Department of Medicinal Chemistry and Pharmacology, University of Science & Technology, Daejeon 34113, Republic of Korea; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon 34114, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2017.10.046DOI Listing
December 2017

Expression of TWIST in the first-trimester trophoblast and decidual tissue of women with recurrent pregnancy losses.

Am J Reprod Immunol 2017 08 24;78(2). Epub 2017 Mar 24.

Reproductive Medicine, Department of Obstetrics and Gynecology, Chicago Medical School at Rosalind Franklin University of Medicine and Science, Vernon Hills, IL, USA.

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http://dx.doi.org/10.1111/aji.12670DOI Listing
August 2017

Minimal pneumothorax with dynamic changes in ST segment similar to myocardial infarction.

Am J Emerg Med 2017 Aug 19;35(8):1210.e1-1210.e4. Epub 2017 Apr 19.

Pusan National University Hospital, Department of Emergency Medicine, 179, Gudeok-ro, Seo-gu, Busan 602-739, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.ajem.2017.04.037DOI Listing
August 2017

Design, synthesis, and biological evaluation of aryl N-methoxyamide derivatives as GPR119 agonists.

Bioorg Med Chem Lett 2017 08 13;27(16):3909-3914. Epub 2017 Jun 13.

Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon 305-600, Republic of Korea; Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2017.06.032DOI Listing
August 2017

PPARγ agonists induce adipocyte differentiation by modulating the expression of Lipin-1, which acts as a PPARγ phosphatase.

Int J Biochem Cell Biol 2016 12 22;81(Pt A):57-66. Epub 2016 Oct 22.

Laboratory of Chemical Biology and Genomics, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, Republic of Korea; University of Science and Technology in Korea, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2016.10.018DOI Listing
December 2016

Effect of thoracic epidural analgesia on recovery of bowel function after major upper abdominal surgery.

J Clin Anesth 2016 Nov 13;34:247-52. Epub 2016 May 13.

Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jclinane.2016.04.042DOI Listing
November 2016

Effect of task-specific training on Eph/ephrin expression after stroke.

BMB Rep 2016 Nov;49(11):635-640

Rehabilitation Medicine, Konkuk University School of Medicine; Center for Neuroscience Research, Institute of Biomedical Science and Technology, Konkuk University, Seoul 05029, Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346325PMC
http://dx.doi.org/10.5483/bmbrep.2016.49.11.172DOI Listing
November 2016

Postoperative Radiotherapy After Limb-sparing Surgery for Soft-tissue Sarcomas of the Distal Extremities.

Anticancer Res 2016 09;36(9):4825-31

Department of Orthopedic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

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http://dx.doi.org/10.21873/anticanres.11044DOI Listing
September 2016

Clinical significance of fatty liver disease induced by tamoxifen and toremifene in breast cancer patients.

Breast 2016 Aug 27;28:67-72. Epub 2016 May 27.

Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43 gil, Songpa-gu, Seoul 05505, Republic of Korea.

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http://dx.doi.org/10.1016/j.breast.2016.04.017DOI Listing
August 2016

Anti-inflammatory effect of a selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor via the stimulation of heme oxygenase-1 in LPS-activated mice and J774.1 murine macrophages.

J Pharmacol Sci 2016 Aug 16;131(4):241-50. Epub 2016 Jul 16.

Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, P.O. Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea; Graduate School of New Drug Discovery and Development, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon 305-764, Republic of Korea; Department of Medicinal Chemistry and Pharmacology, University of Science and Technology, 217 Gajeong-ro, Yuseong-gu, Daejeon 305-333, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jphs.2016.07.003DOI Listing
August 2016

Circulating Plasma Biomarkers for TSU-68, an Oral Antiangiogenic Agent, in Patients with Metastatic Breast Cancer.

Cancer Res Treat 2016 Apr 14;48(2):499-507. Epub 2015 Jul 14.

Department of Medical Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4143/crt.2015.089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843716PMC
April 2016

Prognostic tissue biomarker exploration for patients with metastatic renal cell carcinoma receiving vascular endothelial growth factor receptor tyrosine kinase inhibitors.

Tumour Biol 2016 Apr 3;37(4):4919-27. Epub 2015 Nov 3.

Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, Republic of Korea.

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http://dx.doi.org/10.1007/s13277-015-4339-5DOI Listing
April 2016

Pharmacokinetic characterization of 2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone, a novel 11β-hydroxysteroid dehydrogenase type 1 inhibitor in rats.

Arch Pharm Res 2016 Apr 18;39(4):492-498. Epub 2016 Jan 18.

Drug Discovery Platform Technology Group, Korea Research Institute of Chemical Technology, P.O. Box 107, Yuseong-gu, Daejeon, 305-600, Republic of Korea.

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http://dx.doi.org/10.1007/s12272-015-0702-8DOI Listing
April 2016

Cytoplasmic expression of high mobility group B1 (HMGB1) is associated with tumor-infiltrating lymphocytes (TILs) in breast cancer.

Pathol Int 2016 Apr 27;66(4):202-9. Epub 2016 Feb 27.

Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, South Korea.

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http://dx.doi.org/10.1111/pin.12393DOI Listing
April 2016

Small molecules that allosterically inhibit p21-activated kinase activity by binding to the regulatory p21-binding domain.

Exp Mol Med 2016 Apr 29;48:e229. Epub 2016 Apr 29.

Department of Biochemistry, College of Medicine and Medical Research Center, Chungbuk National University, Cheongju, Korea.

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http://dx.doi.org/10.1038/emm.2016.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855275PMC
April 2016

Expression of FOXM1 and related proteins in breast cancer molecular subtypes.

Int J Exp Pathol 2016 04 9;97(2):170-7. Epub 2016 Jun 9.

Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Songpa-gu, Seoul, Korea.

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http://dx.doi.org/10.1111/iep.12187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926053PMC
April 2016

Long-term outcomes of tyrosine kinase inhibitor discontinuation in patients with metastatic renal cell carcinoma.

Cancer Chemother Pharmacol 2016 Feb 21;77(2):339-47. Epub 2015 Dec 21.

Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, Korea.

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http://dx.doi.org/10.1007/s00280-015-2942-1DOI Listing
February 2016

High mobility group B1 and N1 (HMGB1 and HMGN1) are associated with tumor-infiltrating lymphocytes in HER2-positive breast cancers.

Virchows Arch 2015 Dec 7;467(6):701-709. Epub 2015 Oct 7.

Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.

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http://link.springer.com/content/pdf/10.1007%2Fs00428-015-18
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http://link.springer.com/10.1007/s00428-015-1861-1
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http://dx.doi.org/10.1007/s00428-015-1861-1DOI Listing
December 2015

Comparison Between Phenylephrine and Dopamine in Maintaining Cerebral Oxygen Saturation in Thoracic Surgery: A Randomized Controlled Trial.

Medicine (Baltimore) 2015 Dec;94(49):e2212

From the Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-gu, Seoul, Republic of Korea.

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http://dx.doi.org/10.1097/MD.0000000000002212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008502PMC
December 2015

Clinicopathologic Significance of the Intratumoral Heterogeneity of HER2 Gene Amplification in HER2-Positive Breast Cancer Patients Treated With Adjuvant Trastuzumab.

Am J Clin Pathol 2015 Oct;144(4):570-8

From the Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea;

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http://dx.doi.org/10.1309/AJCP51HCGPOPWSCYDOI Listing
October 2015

A phase 1 study of a heterologous prime-boost vaccination involving a truncated HER2 sequence in patients with HER2-expressing breast cancer.

Mol Ther Methods Clin Dev 2015 30;2:15031. Epub 2015 Sep 30.

Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine , Songpa-Gu, Seoul, Korea.

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http://dx.doi.org/10.1038/mtm.2015.31DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588449PMC
October 2015

Tau and PTEN status as predictive markers for response to trastuzumab and paclitaxel in patients with HER2-positive breast cancer.

Tumour Biol 2015 Aug 1;36(8):5865-71. Epub 2015 Mar 1.

Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, Korea.

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http://dx.doi.org/10.1007/s13277-015-3258-9DOI Listing
August 2015

Pulmonary Metastasectomy Could Prolong Overall Survival in Select Cases of Metastatic Urinary Tract Cancer.

Clin Genitourin Cancer 2015 Aug 2;13(4):e297-e304. Epub 2015 May 2.

Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15587673150009
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http://dx.doi.org/10.1016/j.clgc.2015.04.013DOI Listing
August 2015

Prognostic Significance of Tumor-Infiltrating Lymphocytes and the Tertiary Lymphoid Structures in HER2-Positive Breast Cancer Treated With Adjuvant Trastuzumab.

Am J Clin Pathol 2015 Aug;144(2):278-88

From the Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea;

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http://dx.doi.org/10.1309/AJCPIXUYDVZ0RZ3GDOI Listing
August 2015

Discovery and optimization of adamantane carboxylic acid derivatives as potent diacylglycerol acyltransferase 1 inhibitors for the potential treatment of obesity and diabetes.

Eur J Med Chem 2015 Aug 27;101:716-35. Epub 2015 Jun 27.

Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon 305-600, Republic of Korea; Department of Medicinal and Pharmaceutical Chemistry, University of Science and Technology, 305-333, Republic of Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02235234153011
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http://dx.doi.org/10.1016/j.ejmech.2015.06.043DOI Listing
August 2015

Prognostic and predictive value of NanoString-based immune-related gene signatures in a neoadjuvant setting of triple-negative breast cancer: relationship to tumor-infiltrating lymphocytes.

Breast Cancer Res Treat 2015 Jun 26;151(3):619-27. Epub 2015 May 26.

Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, Korea.

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http://link.springer.com/content/pdf/10.1007/s10549-015-3438
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http://link.springer.com/10.1007/s10549-015-3438-8
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http://dx.doi.org/10.1007/s10549-015-3438-8DOI Listing
June 2015

Vascular endothelial growth factor receptor tyrosine kinase inhibitor (VEGFR-TKI) rechallenge for patients with metastatic renal cell carcinoma after treatment failure using both VEGFR-TKI and mTOR inhibitor.

Cancer Chemother Pharmacol 2015 May 17;75(5):1025-35. Epub 2015 Mar 17.

Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, Korea.

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http://dx.doi.org/10.1007/s00280-015-2725-8DOI Listing
May 2015

Safety and efficacy of a novel, fenestrated aortic arch stent graft with a preloaded catheter for supraaortic arch vessels: an experimental study in Swine.

J Korean Med Sci 2015 Apr 19;30(4):426-34. Epub 2015 Mar 19.

Division of Cardiology, Department of Internal Medicine, College of Medicine, Pusan National University, Medical Research Institute, Pusan National University Hospital, Busan, Korea.

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http://dx.doi.org/10.3346/jkms.2015.30.4.426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366963PMC
April 2015

Correlations between molecular subtypes and pathologic response patterns of breast cancers after neoadjuvant chemotherapy.

Ann Surg Oncol 2015 Feb 6;22(2):392-400. Epub 2014 Sep 6.

Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.

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http://dx.doi.org/10.1245/s10434-014-4054-2DOI Listing
February 2015

Comparable efficacy of silk fibroin with the collagen membranes for guided bone regeneration in rat calvarial defects.

J Adv Prosthodont 2014 Dec 17;6(6):539-46. Epub 2014 Dec 17.

Department of Prosthodontics, Hallym University School of Medicine, Hallym University Sacred Heart Hospital, Anyang, Republic of Korea.

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http://dx.doi.org/10.4047/jap.2014.6.6.539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279054PMC
December 2014

Prognostic significance of the ratio of absolute neutrophil to lymphocyte counts for breast cancer patients with ER/PR-positivity and HER2-negativity in neoadjuvant setting.

Tumour Biol 2014 Oct 2;35(10):9823-30. Epub 2014 Jul 2.

Department of Pathology, Ajou University School of Medicine, Suwon, South Korea.

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http://dx.doi.org/10.1007/s13277-014-2282-5DOI Listing
October 2014

Synthesis and biological evaluation of thienopyrimidine derivatives as GPR119 agonists.

Bioorg Med Chem Lett 2014 Sep 28;24(17):4281-5. Epub 2014 Jul 28.

Drug Discovery Division, Korea Research Institute of Chemical Technology, Republic of Korea; Department of Medicinal and Pharmaceutical Chemistry, University of Science and Technology, 305-333, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2014.07.020DOI Listing
September 2014

Active surveillance for metastatic or recurrent renal cell carcinoma.

J Cancer Res Clin Oncol 2014 Aug 22;140(8):1421-8. Epub 2014 Apr 22.

Department of Oncology, Asan Medical Centre, University of Ulsan College of Medicine, 88 Olympic-Ro 43-Gil, Songpa-gu, Seoul, 138-736, Korea.

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http://dx.doi.org/10.1007/s00432-014-1680-9DOI Listing
August 2014

MET expression is associated with disease-specific survival in breast cancer patients in the neoadjuvant setting.

Pathol Res Pract 2014 Aug 18;210(8):494-500. Epub 2014 Apr 18.

Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 138-736, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.prp.2014.04.002DOI Listing
August 2014

Anti-obesity effects of KR-66195, a synthetic DPP-IV inhibitor, in diet-induced obese mice and obese-diabetic ob/ob mice.

Metabolism 2014 Jun 25;63(6):793-9. Epub 2014 Feb 25.

Department of Internal Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2014.02.011DOI Listing
June 2014

Two histopathologically different diseases: hormone receptor-positive and hormone receptor-negative tumors in HER2-positive breast cancer.

Breast Cancer Res Treat 2014 Jun 13;145(3):615-23. Epub 2014 May 13.

Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, South Korea.

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http://dx.doi.org/10.1007/s10549-014-2983-xDOI Listing
June 2014

Preclinical pharmacokinetic characterization of 2-(4-(4-(5-(2-phenyl-5-(trifluoromethyl)oxazole-4-carboxamido)-1H-benzo[d]imidazol-2-yl)phenyl)cyclohexyl) acetic acid, a novel DGAT-1 inhibitor.

Xenobiotica 2014 May 23;44(5):465-71. Epub 2013 Oct 23.

Drug Discovery Platform Technology Research Group, Division of Bio-organic Science, Korea Research Institute of Chemical Technology , Daejeon , Republic of Korea and.

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http://dx.doi.org/10.3109/00498254.2013.847218DOI Listing
May 2014

Low prognostic implication of fibroblast growth factor family activation in triple-negative breast cancer subsets.

Ann Surg Oncol 2014 May 3;21(5):1561-8. Epub 2014 Jan 3.

Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea,

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http://dx.doi.org/10.1245/s10434-013-3456-xDOI Listing
May 2014

Transport characteristics and transporter-based drug-drug interactions of TM-25659, a novel TAZ modulator.

Biopharm Drug Dispos 2014 Apr 18;35(3):183-94. Epub 2013 Dec 18.

College of Pharmacy, Dankook University, Cheonan, Korea.

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http://dx.doi.org/10.1002/bdd.1883DOI Listing
April 2014

A novel 11β-HSD1 inhibitor improves diabesity and osteoblast differentiation.

J Mol Endocrinol 2014 Apr 6;52(2):191-202. Epub 2014 Mar 6.

Division of Drug Discovery Research, Korea Research Institute of Chemical Technology, PO Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea Division of Life and Pharmaceutical Sciences and Center for Cell Signaling and Drug Discovery Research, College of Pharmacy, Ewha Woman's University, Sedaemoon-gu, Seoul 120-750, Republic of Korea Laboratory of Translational Therapeutics, Korea Research Institute of Chemical Technology, Pharmacology Research Center, PO Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea Department of Toxicology, College of Pharmacy, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon 305-764, Republic of Korea Department of Medicinal and Pharmaceutical Chemistry, University of Science and Technology, 217 Gajeong-ro, Yuseong-gu, Daejeon 305-333, Republic of Korea.

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http://dx.doi.org/10.1530/JME-13-0177DOI Listing
April 2014

KR-62980 suppresses lipid metabolism through inhibition of cytosolic NADP isocitrate dehydrogenase in zebrafish.

Zebrafish 2014 Apr 3;11(2):122-8. Epub 2014 Mar 3.

Drug Discovery Platform Technology Team, Korea Research Institute of Chemical Technology , Daejeon, Republic of Korea.

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http://dx.doi.org/10.1089/zeb.2013.0919DOI Listing
April 2014

Anti-diabetic and anti-inflammatory effect of a novel selective 11β-HSD1 inhibitor in the diet-induced obese mice.

Eur J Pharmacol 2013 Dec 14;721(1-3):70-9. Epub 2013 Oct 14.

Division of Drug Discovery Research, Korea Research Institute of Chemical Technology, P.O.Box 107, Yuseong-gu, Daejeon 305-600, Korea; Department of Toxicology, College of Pharmacy, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon 305-764, Korea.

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http://dx.doi.org/10.1016/j.ejphar.2013.09.052DOI Listing
December 2013