Jill Richardson

Jill Richardson

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Jill Richardson

Jill Richardson

Publications by authors named "Jill Richardson"

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miR-146a and miR-181a are involved in the progression of mild cognitive impairment to Alzheimer's disease.

Neurobiol Aging 2019 Jun 21;82:102-109. Epub 2019 Jun 21.

Genetics Unit, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy; Faculty of Psychology, eCampus University, Novedrate (Como), Italy.

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.06.005DOI Listing
June 2019

Improving Mouse Models for Dementia. Are All the Effects in Tau Mouse Models Due to Overexpression?

Cold Spring Harb Symp Quant Biol 2018 11;83:151-161. Epub 2019 Feb 11.

Department of Neuroscience, Physiology and Pharmacology, University College London, London, WC1E 6BT, United Kingdom.

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http://dx.doi.org/10.1101/sqb.2018.83.037531DOI Listing
February 2019

Editorial: Combining Forces to Improve Alzheimer's Disease Drug Discovery: The Symptomatic Battle.

CNS Neurol Disord Drug Targets 2016 ;15(7):754-5

Department of Pharmacology, University Lille Nord de France, Lille, France.

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January 2018

Evaluating Atlantic bottlenose dolphin (Tursiops truncatus) leukocyte differential counts comparing the CellaVision DM96 and the manual method.

Vet Clin Pathol 2017 Sep 9;46(3):466-470. Epub 2017 Jun 9.

Division of Comparative Pathology, Department of Pathology & Laboratory Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1111/vcp.12514DOI Listing
September 2017

The Continuing Failure of Bexarotene in Alzheimer's Disease Mice.

J Alzheimers Dis 2015 ;46(2):471-82

Laboratory of Biology of Neurodegenerative Disorders, Department of Neuroscience, IRCCS Mario Negri Institute for Pharmacological Research, Milano, Italy.

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http://dx.doi.org/10.3233/JAD-150029DOI Listing
July 2016

Quantitative μPET Imaging of Cerebral Glucose Metabolism and Amyloidosis in the TASTPM Double Transgenic Mouse Model of Alzheimer's Disease.

Curr Alzheimer Res 2015 ;12(7):694-703

Molecular Imaging Center Antwerp, University of Antwerp, Campus DrieEiken - UC, Universiteitsplein 1, 2610 Wilrijk, Beljium.

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April 2016

Deficits of psychomotor and mnesic functions across aging in mouse lemur primates.

Front Behav Neurosci 2014 9;8:446. Epub 2015 Jan 9.

UMR 7179, Centre National de la Recherche Scientifique, Muséum National d'Histoire Naturelle France Brunoy, France.

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http://dx.doi.org/10.3389/fnbeh.2014.00446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288241PMC
January 2015

Memantine prevents reference and working memory impairment caused by sleep deprivation in both young and aged Octodon degus.

Neuropharmacology 2014 Oct 27;85:206-14. Epub 2014 May 27.

Clinical & Experimental Neuroscience (NiCE) and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Universitat Jaume I, 12071 Castellon, Spain; School of Medicine, Campus Mare Nostrum, University of Murcia, 30100 Murcia, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00283908140019
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http://dx.doi.org/10.1016/j.neuropharm.2014.05.023DOI Listing
October 2014

Octodon degus: a model for the cognitive impairment associated with Alzheimer's disease.

CNS Neurosci Ther 2013 Sep 27;19(9):643-8. Epub 2013 May 27.

Clinical & Experimental Neuroscience (NiCE) and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), School of Health Sciences (Medicine), University Jaume I of Castellon, Castellon de la Plana, Spain.

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http://dx.doi.org/10.1111/cns.12125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493546PMC
September 2013

The age-related gliosis and accompanying deficit in spatial learning are unaffected by dimebon.

Neurochem Res 2013 Jun 26;38(6):1190-5. Epub 2012 Sep 26.

Trinity College Institute of Neuroscience and Physiology Department, Trinity College, Dublin, Ireland.

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http://dx.doi.org/10.1007/s11064-012-0884-0DOI Listing
June 2013

Bone marrow-derived mesenchymal stem cells contribute to the reduction of amyloid-β deposits and the improvement of synaptic transmission in a mouse model of pre-dementia Alzheimer's disease.

Curr Alzheimer Res 2013 Jun;10(5):524-31

Stem Cell Neuroplasticity Research Group, Kyungpook National University, Daegu, Korea.

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June 2013

β amyloid peptide plaques fail to alter evoked neuronal calcium signals in APP/PS1 Alzheimer's disease mice.

Neurobiol Aging 2013 Jun 18;34(6):1632-43. Epub 2013 Jan 18.

Department of Neuroscience, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2012.12.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664639PMC
June 2013

Pro-oxidant diet enhances β/γ secretase-mediated APP processing in APP/PS1 transgenic mice.

Neurobiol Aging 2012 May 17;33(5):960-8. Epub 2010 Aug 17.

Wolfson Centre for Age-Related Diseases, King's College London, London, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2010.07.008DOI Listing
May 2012

The neuroprotective effect of a specific P2X₇ receptor antagonist derives from its ability to inhibit assembly of the NLRP3 inflammasome in glial cells.

Brain Pathol 2012 May 27;22(3):295-306. Epub 2011 Oct 27.

Trinity College Institute for Neuroscience, Physiology Department, Trinity College, Dublin, Ireland.

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http://doi.wiley.com/10.1111/j.1750-3639.2011.00531.x
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http://dx.doi.org/10.1111/j.1750-3639.2011.00531.xDOI Listing
May 2012

Rosiglitazone attenuates the age-related changes in astrocytosis and the deficit in LTP.

Neurobiol Aging 2012 Jan 10;33(1):162-75. Epub 2010 Apr 10.

Trinity College Institute of Neuroscience and Physiology Department, Trinity College, Dublin 2, Ireland.

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http://dx.doi.org/10.1016/j.neurobiolaging.2010.02.002DOI Listing
January 2012

Dynamics of Aβ42 reduction in plasma, CSF and brain of rats treated with the γ-secretase modulator, GSM-10h.

Neurodegener Dis 2011 10;8(6):455-64. Epub 2011 Mar 10.

Neurosciences Centre of Excellence for Drug Discovery, GlaxoSmithKline Research and Development Ltd., New Frontiers Science Park, Harlow, UK.

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http://dx.doi.org/10.1159/000324511DOI Listing
December 2011

Alpha-synuclein release by neurons activates the inflammatory response in a microglial cell line.

Neurosci Res 2011 Apr 19;69(4):337-42. Epub 2011 Jan 19.

Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK.

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http://dx.doi.org/10.1016/j.neures.2010.12.020DOI Listing
April 2011

Validation of an automated intact N-terminal propeptide of type I procollagen (PINP) assay.

Clin Biochem 2010 Dec 12;43(18):1453-7. Epub 2010 Oct 12.

Institute of Diagnostics, Department of Clinical Chemistry, University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1016/j.clinbiochem.2010.09.019DOI Listing
December 2010

Dietary manipulation and caloric restriction in the development of mouse models relevant to neurological diseases.

Biochim Biophys Acta 2010 Oct 25;1802(10):840-6. Epub 2010 May 25.

Neurosciences CEDD, GlaxoSmithKline, New Frontiers Science Park North, Third Avenue, Harlow, Essex CM195AW, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S09254439100008
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http://dx.doi.org/10.1016/j.bbadis.2010.04.007DOI Listing
October 2010

Apoptosis-associated tyrosine kinase and neuronal cell death.

Neurochem Res 2010 Apr 26;35(4):588-97. Epub 2009 Nov 26.

Neurosciences Centre of Excellence for Drug Discovery, GlaxoSmithKline Research and Development Limited, New Frontiers Science Park, Harlow, UK.

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http://dx.doi.org/10.1007/s11064-009-0103-9DOI Listing
April 2010

The thiazolidinedione pioglitazone increases cholesterol biosynthetic gene expression in primary cortical neurons by a PPARgamma-independent mechanism.

J Alzheimers Dis 2010 ;19(2):631-46

Department of Neuroscience, MRC Centre for Neurodegeneration Research, King's College London, Institute of Psychiatry, Denmark Hill, London, UK.

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http://dx.doi.org/10.3233/JAD-2010-1266DOI Listing
April 2010

FTY720 ameliorates MOG-induced experimental autoimmune encephalomyelitis by suppressing both cellular and humoral immune responses.

J Neurosci Res 2010 Feb;88(2):346-59

Department of Cellular and Molecular Neuroscience, Division of Neuroscience, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, London, United Kingdom.

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http://dx.doi.org/10.1002/jnr.22196DOI Listing
February 2010

Oligodendrocytes are a novel source of amyloid peptide generation.

Neurochem Res 2009 Dec;34(12):2243-50

Neurosciences Centre of Excellence for Drug Discovery, GlaxoSmithKline Research and Development Limited, New Frontiers Science Park, Third Avenue, Harlow, Essex CM19 5AW, UK.

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http://dx.doi.org/10.1007/s11064-009-0022-9DOI Listing
December 2009

A PPARdelta agonist reduces amyloid burden and brain inflammation in a transgenic mouse model of Alzheimer's disease.

Curr Alzheimer Res 2009 Oct;6(5):431-7

Department of Anethesiology, University of Illinois, & Jesse Brown Veterans Affairs Hospital, Chicago, IL 60612, USA.

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October 2009

Lymphocytes from P2X7-deficient mice exhibit enhanced P2X7 responses.

J Leukoc Biol 2009 Jun 10;85(6):978-86. Epub 2009 Mar 10.

Division of Medicine, Imperial College, Hammersmith Hospital, Du Cane Rd., London W12 0NN, UK.

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http://dx.doi.org/10.1189/jlb.0408251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698584PMC
June 2009

Autoradiographical imaging of PPARgamma agonist effects on PBR/TSPO binding in TASTPM mice.

Exp Neurol 2009 Apr;216(2):459-70

Neuroscience Centre of Excellence for Drug Discovery, GlaxoSmithKline, Third Avenue, Harlow, Essex, CM19 5AW, UK.

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http://dx.doi.org/10.1016/j.expneurol.2009.01.002DOI Listing
April 2009

Abeta(1-42) reduces synapse number and inhibits neurite outgrowth in primary cortical and hippocampal neurons: a quantitative analysis.

J Neurosci Methods 2008 Oct 9;175(1):96-103. Epub 2008 Aug 9.

Neurosciences Centre of Excellence for Drug Discovery, GlaxoSmithKline Research and Development Limited, New Frontiers Science Park, Essex, United Kingdom.

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http://dx.doi.org/10.1016/j.jneumeth.2008.08.001DOI Listing
October 2008

P2x7 deficiency suppresses development of experimental autoimmune encephalomyelitis.

J Neuroinflammation 2008 Aug 8;5:33. Epub 2008 Aug 8.

Department of Anesthesiology, University of Illinois, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1186/1742-2094-5-33DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518548PMC
August 2008

Emergency care and managing toxicoses in the exotic animal patient.

Vet Clin North Am Exot Anim Pract 2008 May;11(2):211-28, v

Milwaukee Emergency Clinic for Animals and Specialty Services, Milwaukee, WI, USA.

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http://dx.doi.org/10.1016/j.cvex.2008.01.002DOI Listing
May 2008

Neuroprotective actions of noradrenaline: effects on glutathione synthesis and activation of peroxisome proliferator activated receptor delta.

J Neurochem 2007 Dec 13;103(5):2092-101. Epub 2007 Sep 13.

Department of Anesthesiology, University of Illinois & Jesse Brown Veteran's Affairs Hospital, Chicago, Illinois, USA.

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http://doi.wiley.com/10.1111/j.1471-4159.2007.04888.x
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http://dx.doi.org/10.1111/j.1471-4159.2007.04888.xDOI Listing
December 2007

Non-cognitive behaviours in an APP/PS1 transgenic model of Alzheimer's disease.

Behav Brain Res 2007 Mar 16;178(1):18-28. Epub 2007 Jan 16.

Neurology & GI CEDD, GlaxoSmithKline Research and Development Limited, New Frontiers Science Park, Third Avenue, Harlow, Essex CM19 5AW, UK.

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http://dx.doi.org/10.1016/j.bbr.2006.11.044DOI Listing
March 2007

Rosiglitazone induces mitochondrial biogenesis in mouse brain.

J Alzheimers Dis 2007 Mar;11(1):45-51

Department of Quantitative Expression, Division of Genetics Research, GlaxoSmithKline, Research Triangle Park, NC 27278, USA.

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March 2007

Protean agonism of the lysophosphatidic acid receptor-1 with Ki16425 reduces nerve growth factor-induced neurite outgrowth in pheochromocytoma 12 cells.

J Neurochem 2006 Sep;98(6):1920-9

Department of Physiology and Pharmacology, Strathclyde Institute for Biomedical Sciences, University of Strathclyde, Glasgow, UK.

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http://dx.doi.org/10.1111/j.1471-4159.2006.04009.xDOI Listing
September 2006

MAPK-activated protein kinase 2 deficiency in microglia inhibits pro-inflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease.

J Biol Chem 2006 Aug 14;281(33):23658-67. Epub 2006 Jun 14.

Neurology & GI Centre of Excellence for Drug Discovery, GlaxoSmithKline Research and Development Limited, New Frontiers Science Park, Third Avenue, Harlow CM19 5AW, Essex, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M513646200DOI Listing
August 2006

P2X(7) receptors on microglial cells mediate injury to cortical neurons in vitro.

Glia 2006 Aug;54(3):234-42

Neurology and GI Centre of Excellence for Drug Discovery, GlaxoSmithKline Research and Development Limited, New Frontiers Science Park, Third Avenue, Harlow CM19 5AW, Essex, United Kingdom.

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http://dx.doi.org/10.1002/glia.20379DOI Listing
August 2006

Protective effects of a peroxisome proliferator-activated receptor-beta/delta agonist in experimental autoimmune encephalomyelitis.

J Neuroimmunol 2005 Nov 10;168(1-2):65-75. Epub 2005 Aug 10.

Department of Anesthesiology, University of Illinois, & Jesse Brown Veteran's Affairs Research Division, Chicago, IL 60612, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S01655728050027
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http://dx.doi.org/10.1016/j.jneuroim.2005.07.006DOI Listing
November 2005

Synaptic transmission and synchronous activity is disrupted in hippocampal slices taken from aged TAS10 mice.

Hippocampus 2005 ;15(1):110-7

Neurology and GI Centre of Excellence for Drug Discovery, GlaxoSmithKline, Harlow, Essex, United Kingdom.

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http://dx.doi.org/10.1002/hipo.20036DOI Listing
May 2005

Fibre diffraction of hair can provide a screening test for Alzheimer's disease: a human and animal model study.

Med Sci Monit 2005 Feb;11(2):CR53-7

Research School of Chemistry, Australian National University, Canberra and Fiberscan Pty Ltd, Robina, Qld, Australia.

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February 2005

Cognitive correlates of Abeta deposition in male and female mice bearing amyloid precursor protein and presenilin-1 mutant transgenes.

Brain Res 2004 Aug;1017(1-2):130-6

Neurology and GI CEDD, GlaxoSmithKline Research and Development Limited, New Frontiers Science Park, Third Avenue, Harlow, Essex, CM19 5AW, UK.

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http://dx.doi.org/10.1016/j.brainres.2004.05.029DOI Listing
August 2004