Jill P Smith

Jill P Smith

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Jill P Smith

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ISG15 pathway knockdown reverses pancreatic cancer cell transformation and decreases murine pancreatic tumor growth via downregulation of PDL-1 expression.

Authors:
Julian Burks Alia Fleury Sarah Livingston Jill P Smith

Cancer Immunol Immunother 2019 Dec 11;68(12):2029-2039. Epub 2019 Nov 11.

Department of Medicine, Georgetown University, Washington, DC, 20007, USA.

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http://dx.doi.org/10.1007/s00262-019-02422-9DOI Listing
December 2019

Vaccine against gastrin, a polyclonal antibody stimulator, decreases pancreatic cancer metastases.

Authors:
Nicholas Osborne Rebecca Sundseth Martha D Gay Hong Cao Robin D Tucker Sandeep Nadella Shangzi Wang Xunxian Liu Alexander Kroemer Lynda Sutton Allen Cato Jill P Smith

Am J Physiol Gastrointest Liver Physiol 2019 Nov 21;317(5):G682-G693. Epub 2019 Aug 21.

Department of Medicine, Georgetown University, Washington, District of Columbia.

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http://dx.doi.org/10.1152/ajpgi.00145.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879893PMC
November 2019

Gastrin vaccine improves response to immune checkpoint antibody in murine pancreatic cancer by altering the tumor microenvironment.

Authors:
Nicholas Osborne Rebecca Sundseth Julian Burks Hong Cao Xunxian Liu Alexander H Kroemer Lynda Sutton Allen Cato Jill P Smith

Cancer Immunol Immunother 2019 Oct 24;68(10):1635-1648. Epub 2019 Sep 24.

Department of Medicine, Georgetown University, 4000 Reservoir Rd, NW, Building D, Room 338, Washington, DC, 20007, USA.

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http://dx.doi.org/10.1007/s00262-019-02398-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814262PMC
October 2019

Cholecystokinin Receptor Antagonist Therapy Decreases Inflammation and Fibrosis in Chronic Pancreatitis.

Authors:
Sandeep Nadella Victor Ciofoaia Hong Cao Bhaskar Kallakury Robin D Tucker Jill P Smith

Dig Dis Sci 2019 Oct 9. Epub 2019 Oct 9.

Department of Medicine, Georgetown University, 4000 Reservoir Rd, NW, Building D, Room 338, Washington, DC, 20007, USA.

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http://dx.doi.org/10.1007/s10620-019-05863-5DOI Listing
October 2019

Endogenous Gastrin Collaborates With Mutant KRAS in Pancreatic Carcinogenesis.

Authors:
Sandeep Nadella Julian Burks Matthew Huber Juan Wang Hong Cao Bhaskar Kallakury Robin D Tucker Simina M Boca Ashley Jermusyck Irene Collins Eveline E Vietsch Mariaelena Pierobon K Alex Hodge Waxing Cui Laufey T Amundadottir Emanuel Petricoin Narayan Shivapurkar Jill P Smith

Pancreas 2019 08;48(7):894-903

From the Department of Medicine.

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http://dx.doi.org/10.1097/MPA.0000000000001360DOI Listing
August 2019

A Cholecystokinin Receptor Antagonist Halts Nonalcoholic Steatohepatitis and Prevents Hepatocellular Carcinoma.

Authors:
Robin D Tucker Victor Ciofoaia Sandeep Nadella Martha D Gay Hong Cao Matthew Huber Anita Safronenka Narayan Shivapurkar Bhaskar Kallakury Annie J Kruger Alexander H K Kroemer Jill P Smith

Dig Dis Sci 2019 Jul 11. Epub 2019 Jul 11.

Department of Medicine, Georgetown University, 4000 Reservoir Rd, NW, Building D, Room 338, Washington, DC, 20007, USA.

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http://dx.doi.org/10.1007/s10620-019-05722-3DOI Listing
July 2019

Dietary fat stimulates pancreatic cancer growth and promotes fibrosis of the tumor microenvironment through the cholecystokinin receptor.

Authors:
Sandeep Nadella Julian Burks Abdulhameed Al-Sabban Gloria Inyang Juan Wang Robin D Tucker Marie E Zamanis William Bukowski Narayan Shivapurkar Jill P Smith

Am J Physiol Gastrointest Liver Physiol 2018 11 21;315(5):G699-G712. Epub 2018 Jun 21.

Department of Medicine, Georgetown University , Washington, District of Columbia.

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https://www.physiology.org/doi/10.1152/ajpgi.00123.2018
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http://dx.doi.org/10.1152/ajpgi.00123.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293257PMC
November 2018

Characterising -regulatory variation in the transcriptome of histologically normal and tumour-derived pancreatic tissues.

Authors:
Mingfeng Zhang Soren Lykke-Andersen Bin Zhu Wenming Xiao Jason W Hoskins Xijun Zhang Lauren M Rost Irene Collins Martijn van de Bunt Jinping Jia Hemang Parikh Tongwu Zhang Lei Song Ashley Jermusyk Charles C Chung Bin Zhu Weiyin Zhou Gail L Matters Robert C Kurtz Meredith Yeager Torben Heick Jensen Kevin M Brown Halit Ongen William R Bamlet Bradley A Murray Mark I McCarthy Stephen J Chanock Nilanjan Chatterjee Brian M Wolpin Jill P Smith Sara H Olson Gloria M Petersen Jianxin Shi Laufey Amundadottir

Gut 2018 03 20;67(3):521-533. Epub 2017 Jun 20.

Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1136/gutjnl-2016-313146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762429PMC
March 2018

Cholecystokinin Receptor-Targeted Polyplex Nanoparticle Inhibits Growth and Metastasis of Pancreatic Cancer.

Authors:
Julian Burks Sandeep Nadella Abdullah Mahmud Charoen Mankongpaisarnrung Juan Wang Jong-In Hahm Robin D Tucker Narayan Shivapurkar Stephan T Stern Jill P Smith

Cell Mol Gastroenterol Hepatol 2018 7;6(1):17-32. Epub 2018 Mar 7.

Department of Medicine, Georgetown University, Washington, District of Columbia.

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https://linkinghub.elsevier.com/retrieve/pii/S2352345X183005
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http://dx.doi.org/10.1016/j.jcmgh.2018.02.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008260PMC
March 2018

Cholecystokinin receptor antagonist alters pancreatic cancer microenvironment and increases efficacy of immune checkpoint antibody therapy in mice.

Authors:
Jill P Smith Shangzi Wang Sandeep Nadella Sandra A Jablonski Louis M Weiner

Cancer Immunol Immunother 2018 02 17;67(2):195-207. Epub 2017 Oct 17.

Department of Oncology, Georgetown Lombardi Comprehensive Cancer Center, Georgetown University, Washington DC, USA.

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http://dx.doi.org/10.1007/s00262-017-2077-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801048PMC
February 2018

Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer.

Authors:
Alison P Klein Brian M Wolpin Harvey A Risch Rachael Z Stolzenberg-Solomon Evelina Mocci Mingfeng Zhang Federico Canzian Erica J Childs Jason W Hoskins Ashley Jermusyk Jun Zhong Fei Chen Demetrius Albanes Gabriella Andreotti Alan A Arslan Ana Babic William R Bamlet Laura Beane-Freeman Sonja I Berndt Amanda Blackford Michael Borges Ayelet Borgida Paige M Bracci Lauren Brais Paul Brennan Hermann Brenner Bas Bueno-de-Mesquita Julie Buring Daniele Campa Gabriele Capurso Giulia Martina Cavestro Kari G Chaffee Charles C Chung Sean Cleary Michelle Cotterchio Frederike Dijk Eric J Duell Lenka Foretova Charles Fuchs Niccola Funel Steven Gallinger J Michael M Gaziano Maria Gazouli Graham G Giles Edward Giovannucci Michael Goggins Gary E Goodman Phyllis J Goodman Thilo Hackert Christopher Haiman Patricia Hartge Manal Hasan Peter Hegyi Kathy J Helzlsouer Joseph Herman Ivana Holcatova Elizabeth A Holly Robert Hoover Rayjean J Hung Eric J Jacobs Krzysztof Jamroziak Vladimir Janout Rudolf Kaaks Kay-Tee Khaw Eric A Klein Manolis Kogevinas Charles Kooperberg Matthew H Kulke Juozas Kupcinskas Robert J Kurtz Daniel Laheru Stefano Landi Rita T Lawlor I-Min Lee Loic LeMarchand Lingeng Lu Núria Malats Andrea Mambrini Satu Mannisto Roger L Milne Beatrice Mohelníková-Duchoňová Rachel E Neale John P Neoptolemos Ann L Oberg Sara H Olson Irene Orlow Claudio Pasquali Alpa V Patel Ulrike Peters Raffaele Pezzilli Miquel Porta Francisco X Real Nathaniel Rothman Ghislaine Scelo Howard D Sesso Gianluca Severi Xiao-Ou Shu Debra Silverman Jill P Smith Pavel Soucek Malin Sund Renata Talar-Wojnarowska Francesca Tavano Mark D Thornquist Geoffrey S Tobias Stephen K Van Den Eeden Yogesh Vashist Kala Visvanathan Pavel Vodicka Jean Wactawski-Wende Zhaoming Wang Nicolas Wentzensen Emily White Herbert Yu Kai Yu Anne Zeleniuch-Jacquotte Wei Zheng Peter Kraft Donghui Li Stephen Chanock Ofure Obazee Gloria M Petersen Laufey T Amundadottir

Nat Commun 2018 02 8;9(1):556. Epub 2018 Feb 8.

Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1038/s41467-018-02942-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805680PMC
February 2018

Effect of liver histopathology on islet cell engraftment in the model mimicking autologous islet cell transplantation.

Authors:
Chirag S Desai Khalid M Khan Xiaobo Ma Henghong Li Juan Wang Lijuan Fan Guoling Chen Jill P Smith Wanxing Cui

Islets 2017 11 13;9(6):140-149. Epub 2017 Sep 13.

c Islet Cell Laboratory, Medstar Georgetown University Hospital , Washington DC , USA.

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http://dx.doi.org/10.1080/19382014.2017.1356558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710696PMC
November 2017

Effective encapsulation and biological activity of phosphorylated chemotherapeutics in calcium phosphosilicate nanoparticles for the treatment of pancreatic cancer.

Authors:
Welley S Loc Samuel S Linton Zachary R Wilczynski Gail L Matters Christopher O McGovern Thomas Abraham Todd Fox Christopher M Gigliotti Xiaomeng Tang Amra Tabakovic Jo Ann Martin Gary A Clawson Jill P Smith Peter J Butler Mark Kester James H Adair

Nanomedicine 2017 Oct 1;13(7):2313-2324. Epub 2017 Jul 1.

Department of Materials Science and Engineering, Pennsylvania State University, University Park, PA, USA; Department of Pharmacology, Pennsylvania State University College of Medicine, Hershey, PA, USA; Department of Biomedical Engineering/Bioengineering, Pennsylvania State University, University Park, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2017.06.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625839PMC
October 2017

Gastrin and Gastric Cancer.

Authors:
Jill P Smith Sandeep Nadella Nick Osborne

Cell Mol Gastroenterol Hepatol 2017 Jul 14;4(1):75-83. Epub 2017 Mar 14.

Cato Research, Durham, North Carolina.

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http://dx.doi.org/10.1016/j.jcmgh.2017.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439238PMC
July 2017

A Cholecystokinin B Receptor-Specific DNA Aptamer for Targeting Pancreatic Ductal Adenocarcinoma.

Authors:
Gary A Clawson Thomas Abraham Weihua Pan Xiaomeng Tang Samuel S Linton Christopher O McGovern Welley S Loc Jill P Smith Peter J Butler Mark Kester James H Adair Gail L Matters

Nucleic Acid Ther 2017 Feb 18;27(1):23-35. Epub 2016 Oct 18.

5 Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine , Hershey, Pennsylvania.

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http://dx.doi.org/10.1089/nat.2016.0621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312616PMC
February 2017

The Role of Gastrin and CCK Receptors in Pancreatic Cancer and other Malignancies.

Authors:
Jill P Smith Lionel K Fonkoua Terry W Moody

Int J Biol Sci 2016 28;12(3):283-91. Epub 2016 Jan 28.

3. National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.7150/ijbs.14952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753157PMC
December 2016

Germline Mutation of the CCK Receptor: A Novel Biomarker for Pancreas Cancer.

Authors:
Jelal Alsubai Gail L Matters Christopher O McGovern Jiangang Liao Evan L Gilius Jill P Smith

Clin Transl Gastroenterol 2016 Jan 7;7:e134. Epub 2016 Jan 7.

Department of Medicine, Pennsylvania State University School of Medicine, Hershey, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ctg.2015.61DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737870PMC
January 2016

Distribution of cholecystokinin-B receptor genotype between patients with pancreatic cancer and controls and its impact on survival.

Authors:
Jill P Smith David C Whitcomb Gail L Matters Randall E Brand Jiangang Liao Yu-Jing Huang Marsha L Frazier

Pancreas 2015 Mar;44(2):236-42

From the *Department of Medicine, Georgetown University, Washington, DC; †Department of Medicine, Pennsylvania State University, College of Medicine, Hershey; ‡Department of Medicine, University of Pittsburgh; §University of Pittsburgh Medical Center, Pittsburgh; Departments of ∥Biochemistry and Molecular Biology, and ¶Public Health Sciences, Pennsylvania State University, College of Medicine, Hershey, PA; and #Department of Epidemiology, University of Texas at MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1097/MPA.0000000000000263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326549PMC
March 2015

Cholecystokinin receptor antagonist halts progression of pancreatic cancer precursor lesions and fibrosis in mice.

Authors:
Jill P Smith Timothy K Cooper Christopher O McGovern Evan L Gilius Qing Zhong Jiangang Liao Alfredo A Molinolo J Silvio Gutkind Gail L Matters

Pancreas 2014 Oct;43(7):1050-9

From the *National Institute of Diabetes and Digestive and Kidney Disease, The National Institutes of Health, Bethesda, MD; Departments of †Medicine, ‡Comparative Medicine and Pathology, §Public Health Sciences, and ∥Biochemistry and Molecular Biology, The Pennsylvania State University, College of Medicine, Hershey, PA; and ¶National Institute of Dental and Craniofacial Research, The National Institutes of Health, Bethesda, MD.

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https://insights.ovid.com/crossref?an=00006676-201410000-000
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http://dx.doi.org/10.1097/MPA.0000000000000194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161619PMC
October 2014

Novel strategies for managing pancreatic cancer.

Authors:
Welley S Loc Jill P Smith Gail Matters Mark Kester James H Adair

World J Gastroenterol 2014 Oct;20(40):14717-25

Welley S Loc, Department of Chemistry, The Pennsylvania State University, University Park, PA 16802, United States.

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http://dx.doi.org/10.3748/wjg.v20.i40.14717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209537PMC
October 2014

Cholecystokinin mediates progression and metastasis of pancreatic cancer associated with dietary fat.

Authors:
Gail L Matters Timothy K Cooper Christopher O McGovern Evan L Gilius Jiangang Liao Brian M Barth Mark Kester Jill P Smith

Dig Dis Sci 2014 Jun 11;59(6):1180-91. Epub 2014 May 11.

Department of Biochemistry and Molecular Biology, College of Medicine, The Pennsylvania State University, Hershey, PA, 17033, USA.

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http://dx.doi.org/10.1007/s10620-014-3201-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096234PMC
June 2014

Cholecystokinin and pancreatic cancer: the chicken or the egg?

Authors:
Jill P Smith Travis E Solomon

Am J Physiol Gastrointest Liver Physiol 2014 Jan 31;306(2):G91-G101. Epub 2013 Oct 31.

6707 Democracy Blvd., Rm. 655, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892.

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http://dx.doi.org/10.1152/ajpgi.00301.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073990PMC
January 2014

Pancreatitis-diabetes-pancreatic cancer: summary of an NIDDK-NCI workshop.

Authors:
Dana K Andersen Åke Andren-Sandberg Eric J Duell Michael Goggins Murray Korc Gloria M Petersen Jill P Smith David C Whitcomb

Pancreas 2013 Nov;42(8):1227-37

From the *Division of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD; †Department of Surgery, Karolinska Institute, Stockholm, Sweden; ‡Unit of Nutrition, Environment and Cancer, Catalan Institute of Oncology, Barcelona, Spain; §Departments of Medicine and Pathology, Johns Hopkins University School of Medicine, Baltimore, MD; ∥Departments of Medicine and Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN; ¶Department of Epidemiology, Mayo Graduate School of Medicine, Rochester, MN; and #Departments of Medicine, Cell Biology and Physiology, and Human Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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http://dx.doi.org/10.1097/MPA.0b013e3182a9ad9dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878448PMC
November 2013

Gaps and opportunities in pancreatic disease research.

Authors:
Dana K Andersen Jill P Smith Jose Serrano Stephen P James

Pancreas 2013 May;42(4):555-6

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http://dx.doi.org/10.1097/MPA.0b013e31828db1ceDOI Listing
May 2013

Safety and tolerability of low-dose naltrexone therapy in children with moderate to severe Crohn's disease: a pilot study.

Authors:
Jill P Smith Douglas Field Sandra I Bingaman Robert Evans David T Mauger

J Clin Gastroenterol 2013 Apr;47(4):339-45

Department of Medicine, College of Medicine, Pennsylvania State University, Hershey, PA 17033, USA.

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http://dx.doi.org/10.1097/MCG.0b013e3182702f2bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586944PMC
April 2013

Therapeutic effect of vitamin d supplementation in a pilot study of Crohn's patients.

Authors:
Linlin Yang Veronika Weaver Jill P Smith Sandra Bingaman Terryl J Hartman Margherita T Cantorna

Clin Transl Gastroenterol 2013 Apr 18;4:e33. Epub 2013 Apr 18.

Department of Veterinary and Biomedical Science, Center for Molecular Immunology and Infectious Disease, University Park, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ctg.2013.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636524PMC
April 2013

PhotoImmunoNanoTherapy reveals an anticancer role for sphingosine kinase 2 and dihydrosphingosine-1-phosphate.

Authors:
Brian M Barth Sriram S Shanmugavelandy James M Kaiser Christopher McGovern Erhan İ Altınoğlu Jeremy K Haakenson Jeremy A Hengst Evan L Gilius Sarah A Knupp Todd E Fox Jill P Smith Timothy M Ritty James H Adair Mark Kester

ACS Nano 2013 Mar 14;7(3):2132-44. Epub 2013 Feb 14.

Department of Pharmacology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, United States.

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http://dx.doi.org/10.1021/nn304862bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757127PMC
March 2013

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.

Authors:
David C Whitcomb Jessica LaRusch Alyssa M Krasinskas Lambertus Klei Jill P Smith Randall E Brand John P Neoptolemos Markus M Lerch Matt Tector Bimaljit S Sandhu Nalini M Guda Lidiya Orlichenko Samer Alkaade Stephen T Amann Michelle A Anderson John Baillie Peter A Banks Darwin Conwell Gregory A Coté Peter B Cotton James DiSario Lindsay A Farrer Chris E Forsmark Marianne Johnstone Timothy B Gardner Andres Gelrud William Greenhalf Jonathan L Haines Douglas J Hartman Robert A Hawes Christopher Lawrence Michele Lewis Julia Mayerle Richard Mayeux Nadine M Melhem Mary E Money Thiruvengadam Muniraj Georgios I Papachristou Margaret A Pericak-Vance Joseph Romagnuolo Gerard D Schellenberg Stuart Sherman Peter Simon Vijay P Singh Adam Slivka Donna Stolz Robert Sutton Frank Ulrich Weiss C Mel Wilcox Narcis Octavian Zarnescu Stephen R Wisniewski Michael R O'Connell Michelle L Kienholz Kathryn Roeder M Michael Barmada Dhiraj Yadav Bernie Devlin

Nat Genet 2012 Dec 11;44(12):1349-54. Epub 2012 Nov 11.

Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1038/ng.2466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510344PMC
December 2012

Downregulation of the CCK-B receptor in pancreatic cancer cells blocks proliferation and promotes apoptosis.

Authors:
Kristin K Fino Gail L Matters Christopher O McGovern Evan L Gilius Jill P Smith

Am J Physiol Gastrointest Liver Physiol 2012 Jun 22;302(11):G1244-52. Epub 2012 Mar 22.

Department of Medicine, College of Medicine, Pennsylvania State University, Hershey, 17033, USA.

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http://dx.doi.org/10.1152/ajpgi.00460.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378167PMC
June 2012

Calcium phosphosilicate nanoparticles for imaging and photodynamic therapy of cancer.

Authors:
Diana M Tacelosky Amy E Creecy Sriram S Shanmugavelandy Jill P Smith David F Claxton James H Adair Mark Kester Brian M Barth

Discov Med 2012 Apr;13(71):275-85

Department of Pharmacology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA.

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April 2012

A single nucleotide polymorphism of the cholecystokinin-B receptor predicts risk for pancreatic cancer.

Authors:
Jill P Smith John F Harms Gail L Matters Christopher O McGovern Francesca M Ruggiero Jiangang Liao Kristin K Fino Emily E Ortega Evan L Gilius John A Phillips

Cancer Biol Ther 2012 Feb 1;13(3):164-74. Epub 2012 Feb 1.

Penn State Hershey Medical Center, Medicine, Gastroenterology, Hershey, PA USA.

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http://dx.doi.org/10.4161/cbt.13.3.18698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336072PMC
February 2012

Therapy with the opioid antagonist naltrexone promotes mucosal healing in active Crohn's disease: a randomized placebo-controlled trial.

Authors:
Jill P Smith Sandra I Bingaman Francesca Ruggiero David T Mauger Aparna Mukherjee Christopher O McGovern Ian S Zagon

Dig Dis Sci 2011 Jul 8;56(7):2088-97. Epub 2011 Mar 8.

Department of Medicine, The Pennsylvania State University, College of Medicine, GI Medicine H-045, 500 University Drive, Hershey, PA 17033, USA.

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http://dx.doi.org/10.1007/s10620-011-1653-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381945PMC
July 2011

Role of endogenous cholecystokinin on growth of human pancreatic cancer.

Authors:
Gail L Matters Christopher McGovern John F Harms Kevin Markovic Krystal Anson Calpurnia Jayakumar Melissa Martenis Christina Awad Jill P Smith

Int J Oncol 2011 Mar 24;38(3):593-601. Epub 2010 Dec 24.

Department of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.

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http://dx.doi.org/10.3892/ijo.2010.886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282828PMC
March 2011

Bioconjugation of calcium phosphosilicate composite nanoparticles for selective targeting of human breast and pancreatic cancers in vivo.

Authors:
Brian M Barth Rahul Sharma Erhan I Altinoğlu Thomas T Morgan Sriram S Shanmugavelandy James M Kaiser Christopher McGovern Gail L Matters Jill P Smith Mark Kester James H Adair

ACS Nano 2010 Mar;4(3):1279-87

Department of Materials Science and Engineering, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.

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http://dx.doi.org/10.1021/nn901297qDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894697PMC
March 2010

Opioid growth factor improves clinical benefit and survival in patients with advanced pancreatic cancer.

Authors:
Jill P Smith Sandra I Bingaman David T Mauger Harold H Harvey Laurence M Demers Ian S Zagon

Open Access J Clin Trials 2010 Mar;2010(2):37-48

Department of Medicine, Pennsylvania State University, College of Medicine, Hershey Medical Center, Hershey, PA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947031PMC
http://dx.doi.org/10.2147/oajct.s8270DOI Listing
March 2010

Growth of human pancreatic cancer is inhibited by down-regulation of gastrin gene expression.

Authors:
Gail L Matters John F Harms Christopher O McGovern Calpurnia Jayakumar Keisha Crepin Zachary P Smith Melissa C Nelson Heather Stock Craig W Fenn James Kaiser Mark Kester Jill P Smith

Pancreas 2009 Jul;38(5):e151-61

Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, PA 17011, USA.

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http://dx.doi.org/10.1097/MPA.0b013e3181a66fdcDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704379PMC
July 2009

Surgical management of portal hypertension in Felty's syndrome: A case report and literature review.

Authors:
Heather Stock Zakiyah Kadry Jill P Smith

J Hepatol 2009 Apr 12;50(4):831-5. Epub 2009 Feb 12.

Department of Internal Medicine, Harrisburg Hospital, Harriburg, PA, USA.

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http://dx.doi.org/10.1016/j.jhep.2008.10.035DOI Listing
April 2009

The opioid antagonist naltrexone improves murine inflammatory bowel disease.

Authors:
Gail L Matters John F Harms Christopher McGovern Leo Fitzpatrick Anuj Parikh Nicholas Nilo Jill P Smith

J Immunotoxicol 2008 Apr;5(2):179-87

Departments of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA.

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http://dx.doi.org/10.1080/15476910802131469DOI Listing
April 2008

Low-dose naltrexone therapy improves active Crohn's disease.

Authors:
Jill P Smith Heather Stock Sandra Bingaman David Mauger Moshe Rogosnitzky Ian S Zagon

Am J Gastroenterol 2007 Apr 11;102(4):820-8. Epub 2007 Jan 11.

Department of Medicine, Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA.

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http://dx.doi.org/10.1111/j.1572-0241.2007.01045.xDOI Listing
April 2007

Combination chemotherapy with gemcitabine and biotherapy with opioid growth factor (OGF) enhances the growth inhibition of pancreatic adenocarcinoma.

Authors:
Ian S Zagon Jeffrey R Jaglowski Michael F Verderame Jill P Smith Alphonse E Leure-Dupree Patricia J McLaughlin

Cancer Chemother Pharmacol 2005 Nov 10;56(5):510-20. Epub 2005 Jun 10.

Department of Neural and Behavioral Sciences, H109, Milton S. Hershey Medical Center, The Pennsylvania State University, Hershey, 17033, USA.

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http://dx.doi.org/10.1007/s00280-005-1028-xDOI Listing
November 2005

The functional significance of the cholecystokinin-C (CCK-C) receptor in human pancreatic cancer.

Authors:
Jill P Smith Wayne B Stanley Michael F Verderame Ian S Zagon

Pancreas 2004 Nov;29(4):271-7

Department of Medicine, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.

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http://dx.doi.org/10.1097/00006676-200411000-00005DOI Listing
November 2004

Amantadine therapy for chronic hepatitis C: a dose escalation study.

Authors:
Jill P Smith Thomas R Riley Sandra Bingaman David T Mauger

Am J Gastroenterol 2004 Jun;99(6):1099-104

Department of Medicine, Pennsylvania State University College of Medicine, The M.S. Hershey Medical Center, Hershey, Pennsylvania 17033-0850, USA.

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http://dx.doi.org/10.1111/j.1572-0241.2004.30798.xDOI Listing
June 2004

Amantadine therapy for chronic hepatitis C.

Authors:
Jill P Smith Thomas R Riley Attila Devenyi Sandra I Bingaman Allen Kunselman

J Gen Intern Med 2004 Jun;19(6):662-8

Department of Medicine, Pennsylvania State College of Medicine, The Milton S Hershey Medical Center, Hershey, PA 17033-0850, USA.

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http://dx.doi.org/10.1111/j.1525-1497.2004.30057.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1492374PMC
June 2004

Functional significance of gastrin gene expression in human cancer cells.

Authors:
Jill P Smith Michael F Verderame Elizabeth N Ballard Ian S Zagon

Regul Pept 2004 Mar;117(3):167-73

Department of Medicine, Pennsylvania State University College of Medicine, The Milton S. Hershey Medical Center, Hershey, PA 17033, USA.

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http://dx.doi.org/10.1016/j.regpep.2003.10.013DOI Listing
March 2004

Treatment of advanced pancreatic cancer with opioid growth factor: phase I.

Authors:
Jill P Smith Robert L Conter Sandra I Bingaman Harold A Harvey David T Mauger Mejdi Ahmad Lawrence M Demers Wayne B Stanley Patricia J McLaughlin Ian S Zagon

Anticancer Drugs 2004 Mar;15(3):203-9

Department of Medicine, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.

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http://dx.doi.org/10.1097/00001813-200403000-00003DOI Listing
March 2004

Characterization of the CCK-C (cancer) receptor in human pancreatic cancer.

Authors:
Jill P Smith Michael F Verderame Patricia McLaughlin Melissa Martenis Elizabeth Ballard Ian S Zagon

Int J Mol Med 2002 Dec;10(6):689-94

Department of Medicine, Pennsylvania State University, College of Medicine, Hershey, PA 17033, USA.

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December 2002