Jill M Siegfried

Jill M Siegfried

UNVERIFIED PROFILE

Are you Jill M Siegfried?   Register this Author

Register author
Jill M Siegfried

Jill M Siegfried

Publications by authors named "Jill M Siegfried"

Are you Jill M Siegfried?   Register this Author

100Publications

1706Reads

23Profile Views

Inhibiting Pathways Predicted From a Steroid Hormone Gene Signature Yields Synergistic Antitumor Effects in NSCLC.

J Thorac Oncol 2020 Jan 10;15(1):62-79. Epub 2019 Oct 10.

Department of Pharmacology, University of Minnesota, Minneapolis, Minnesota; Department of Pharmacology, University of Minnesota, Minneapolis, Minnesota; Department of Pharmacology & Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtho.2019.09.195DOI Listing
January 2020

Status of Agents Targeting the HGF/c-Met Axis in Lung Cancer.

Cancers (Basel) 2018 Aug 21;10(9). Epub 2018 Aug 21.

Department of Pharmacology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/cancers10090280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162713PMC
August 2018

Preclinical Evidence for Combined Use of Aromatase Inhibitors and NSAIDs as Preventive Agents of Tobacco-Induced Lung Cancer.

J Thorac Oncol 2018 03 9;13(3):399-412. Epub 2017 Dec 9.

Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Pharmacology, University of Minnesota, Minneapolis, Minnesota.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtho.2017.11.126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825271PMC
March 2018

Clinical Utility of Chromosomal Aneusomy in Individuals at High Risk of Lung Cancer.

J Thorac Oncol 2017 10 19;12(10):1512-1523. Epub 2017 Jun 19.

Department of Medicine, Division of Medical Oncology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado; Department of Pathology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtho.2017.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647865PMC
October 2017

Interaction between the estrogen receptor and fibroblast growth factor receptor pathways in non-small cell lung cancer.

Oncotarget 2017 Apr;8(15):24063-24076

Department of Pharmacology & Chemical Biology and University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.16030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421827PMC
April 2017

KRAS and TP53 mutations in bronchoscopy samples from former lung cancer patients.

Mol Carcinog 2017 02 6;56(2):381-388. Epub 2016 Jun 6.

Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mc.22501DOI Listing
February 2017

ATM protein is deficient in over 40% of lung adenocarcinomas.

Oncotarget 2016 09;7(36):57714-57725

Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.9757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295384PMC
September 2016

Lung Cancer Risk Prediction Using Common SNPs Located in GWAS-Identified Susceptibility Regions.

J Thorac Oncol 2015 Nov;10(11):1538-45

Departments of *Epidemiology and †Biostatistics, Graduate School of Public Health, Pittsburgh, Pennsylvania; Departments of ‡Medicine, §Radiology, and ‖Cardiothoracic Surgery, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania; and ¶Department of Pharmacology, School of Medicine, University of Minnesota, Minneapolis, Minnesota.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/JTO.0000000000000666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636453PMC
November 2015

Expression of PAM50 Genes in Lung Cancer: Evidence that Interactions between Hormone Receptors and HER2/HER3 Contribute to Poor Outcome.

Neoplasia 2015 Nov;17(11):817-25

Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15213; University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA 15213. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neo.2015.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681883PMC
November 2015

Functional analyses of ATM, ATR and Fanconi anemia proteins in lung carcinoma : ATM, ATR and FA in lung carcinoma.

BMC Cancer 2015 Oct 5;15:649. Epub 2015 Oct 5.

Department of Radiation Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12885-015-1649-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595318PMC
October 2015

Epigenetic Repression of CCDC37 and MAP1B Links Chronic Obstructive Pulmonary Disease to Lung Cancer.

J Thorac Oncol 2015 Aug;10(8):1181-8

*Lung Cancer Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico; †Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania; ‡Department of Pharmacology, University of Minnesota, Minneapolis, Minnesota; and §COPD Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/JTO.0000000000000592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511946PMC
August 2015

15q12 variants, sputum gene promoter hypermethylation, and lung cancer risk: a GWAS in smokers.

J Natl Cancer Inst 2015 Feb 23;107(5). Epub 2015 Feb 23.

: Lung Cancer Program, Lovelace Respiratory Research Institute, Albuquerque, NM (SL, YL, CLT, MAP, RPW, KCD, XZ, EAB, YT, SAB); Department of Epidemiology, Graduate School of Public Health (JLW) and Department of Medicine (TN, MR), University of Pittsburgh, Pittsburgh, PA; Center for Genomic Medicine, Department of Community and Family Medicine, Geisel School of Medicine, Dartmouth College, Hanover, NH (YH, CIA); Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA (CKE, DVDB, WJG, FDG); Department of Pharmacology & Chemical Biology, Hillman Cancer Center of the University of Pittsburgh Medical Center, Pittsburgh, PA (ALGD, JMS); Department of Internal Medicine, University of New Mexico, Albuquerque, NM (REC, CAS); Department of Pharmacology, University of Minnesota, Minneapolis, MN (JMS).

View Article

Download full-text PDF

Source
http://jnci.oxfordjournals.org/content/107/5/djv035.full.pdf
Web Search
http://jnci.oxfordjournals.org/cgi/doi/10.1093/jnci/djv035
Publisher Site
http://dx.doi.org/10.1093/jnci/djv035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555640PMC
February 2015

Co-targeting c-Met and COX-2 leads to enhanced inhibition of lung tumorigenesis in a murine model with heightened airway HGF.

J Thorac Oncol 2014 Sep;9(9):1285-93

Departments of *Pharmacology and Chemical Biology and †Biostatistics, University of Pittsburgh, Pittsburgh, Pennsylvania; and ‡Department of Pharmacology, University of Minnesota, Minneapolis, Minnesota.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/JTO.0000000000000245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134355PMC
September 2014

Inherited variation in the ATP-binding cassette transporter ABCB1 and survival after chemotherapy for stage III-IV lung cancer.

J Thorac Oncol 2014 Sep;9(9):1264-71

*University of Pittsburgh Cancer Institute and †Department of Epidemiology, University of Pittsburgh Graduate School of Public Health; ‡Division of Hematology/Oncology, Department of Medicine, University of Pittsburgh School of Medicine; §Department of Medicine, University of Pittsburgh School of Medicine; ‖Department of Cardiothoracic Surgery, University of Pittsburgh School of Medicine; ¶Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15560864153067
Publisher Site
http://dx.doi.org/10.1097/JTO.0000000000000262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134100PMC
September 2014

Pan-erbB inhibition potentiates BRAF inhibitors for melanoma treatment.

Melanoma Res 2014 Jun;24(3):207-18

aDepartment of Pharmacology and Chemical Biology, University of Pittsburgh Cancer Institute Departments of bPathology cMedicine, University of Pittsburgh dDepartment of Dermatology, University of Pittsburgh Medical Center eDepartment of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania fDepartment of Internal Medicine, Division of Epidemiology and Biostatistics, University of New Mexico, Albuquerque, New Mexico gDepartment of Pharmacology, University of Minnesota, Minneapolis, Minnesota, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CMR.0000000000000060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394744PMC
June 2014

Erlotinib, erlotinib-sulindac versus placebo: a randomized, double-blind, placebo-controlled window trial in operable head and neck cancer.

Clin Cancer Res 2014 Jun 11;20(12):3289-98. Epub 2014 Apr 11.

Authors' Affiliations: Division of Head and Neck Surgery, Department of Otolaryngology, Oregon Health and Science University, Portland, Oregon; Division of Hematology/Oncology, Department of Internal Medicine; Department of Pharmacology and Chemical Biology;Biostatistics Facility, University of Pittsburgh, University of Pittsburgh Cancer Institute; Departments of Otolaryngology and Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Otolaryngology, University of Kansas Medical Center, Kansas City, Kansas; Women's Health Integrated Research Center, Gynecologic Cancer Center of Excellence, Annandale, Virginia; Division of Hematology/Oncology, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts; and Department of Pharmacology, University of Minnesota, Minneapolis, Minnesota.

View Article

Download full-text PDF

Source
http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
Publisher Site
http://dx.doi.org/10.1158/1078-0432.CCR-13-3360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104657PMC
June 2014

Estrongenic steroid hormones in lung cancer.

Semin Oncol 2014 Feb 12;41(1):5-16. Epub 2013 Dec 12.

Department of Pharmacology & Chemical Biology, University of Pittsburgh, Pittsburgh, PA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00937754130021
Publisher Site
http://dx.doi.org/10.1053/j.seminoncol.2013.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001725PMC
February 2014

RET rearrangements in lung adenocarcinoma and radiation.

J Thorac Oncol 2014 Jan;9(1):118-20

Departments of *Pathology, †Pharmacology, University of Pittsburgh; and 3University of Pittsburgh Cancer Institute, University of Pittsburgh, School of Medicine/Hematology-Oncology, Pittsburgh, Pennsylvania.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15560864153017
Publisher Site
http://dx.doi.org/10.1097/JTO.0000000000000015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836180PMC
January 2014

Smoking out reproductive hormone actions in lung cancer.

Authors:
Jill M Siegfried

Mol Cancer Res 2014 Jan 7;12(1):24-31. Epub 2014 Jan 7.

University of Minnesota, 6-120 Jackson Hall, 321 Church Street SE, Minneapolis, MN 55455-0217.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1541-7786.MCR-13-0580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972805PMC
January 2014

Phase I trial of carboplatin and etoposide in combination with panobinostat in patients with lung cancer.

Anticancer Res 2013 Oct;33(10):4475-81

University of Pittsburgh Cancer Institute, UPMC Cancer Pavilion, 5150 Centre Avenue (555), Pittsburgh, PA 15232, U.S.A.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157617PMC
October 2013

Genetic variation in ESR2 and estrogen receptor-beta expression in lung tumors.

Cancer Epidemiol 2013 Aug 23;37(4):518-22. Epub 2013 Apr 23.

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh and University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canep.2013.03.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684046PMC
August 2013

The prognostic and predictive value of KRAS oncogene substitutions in lung adenocarcinoma.

Cancer 2013 Jun 22;119(12):2268-74. Epub 2013 Mar 22.

University of Pittsburgh Cancer Institute, School of Medicine/Hematology-Oncology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/cncr.28039
Publisher Site
http://dx.doi.org/10.1002/cncr.28039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674175PMC
June 2013

Optimal threshold in CT quantification of emphysema.

Eur Radiol 2013 Apr 1;23(4):975-84. Epub 2012 Nov 1.

Department of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00330-012-2683-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573224PMC
April 2013

Computerized identification of airway wall in CT examinations using a 3D active surface evolution approach.

Med Image Anal 2013 Apr 29;17(3):283-96. Epub 2012 Nov 29.

Department of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.media.2012.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606689PMC
April 2013

c-Src activation mediates erlotinib resistance in head and neck cancer by stimulating c-Met.

Clin Cancer Res 2013 Jan 4;19(2):380-92. Epub 2012 Dec 4.

Departments of Pharmacology & Chemical Biology and Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-12-1555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549019PMC
January 2013

Prevention of tobacco carcinogen-induced lung cancer in female mice using antiestrogens.

Carcinogenesis 2012 Nov 2;33(11):2181-9. Epub 2012 Aug 2.

Department of Pharmacology & Chemical Biology, University of Pittsburgh and University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA.

View Article

Download full-text PDF

Source
https://academic.oup.com/carcin/article-lookup/doi/10.1093/c
Publisher Site
http://dx.doi.org/10.1093/carcin/bgs260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584962PMC
November 2012

Genetic variability in DNA repair and cell cycle control pathway genes and risk of smoking-related lung cancer.

Mol Carcinog 2012 Oct 4;51 Suppl 1:E11-20. Epub 2011 Oct 4.

Center for Clinical Pharmacology, University of Pittsburgh School of Medicine, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mc.20858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289753PMC
October 2012

Automated lobe-based airway labeling.

Int J Biomed Imaging 2012 9;2012:382806. Epub 2012 Oct 9.

Department of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2012/382806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474277PMC
October 2012

Illustration of the obstacles in computerized lung segmentation using examples.

Med Phys 2012 Aug;39(8):4984-91

Department of Structural Biology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1118/1.4737023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416879PMC
August 2012

Anatomic segmentectomy for the solitary pulmonary nodule and early-stage lung cancer.

Ann Thorac Surg 2012 Jun 6;93(6):1780-5; discussion 1786-7. Epub 2012 Apr 6.

Division of Thoracic and Foregut Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15232, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.athoracsur.2011.11.074DOI Listing
June 2012

CT based computerized identification and analysis of human airways: a review.

Med Phys 2012 May;39(5):2603-16

Department of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1118/1.4703901DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344883PMC
May 2012

Combining the multitargeted tyrosine kinase inhibitor vandetanib with the antiestrogen fulvestrant enhances its antitumor effect in non-small cell lung cancer.

J Thorac Oncol 2012 Mar;7(3):485-95

Department of Pharmacology & Chemical Biology, University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/JTO.0b013e31824177eaDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288546PMC
March 2012

Influence of age and IB status after resection of node-negative non-small cell lung cancer.

Ann Thorac Surg 2012 Mar;93(3):929-35; discussion 935-6

Division of Thoracic and Foregut Surgery, Heart, Lung and Esophageal Surgery Institute, University of Pittsburgh Medical Center Health System, Pittsburgh, Pennsylvania 15232, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.athoracsur.2011.09.047DOI Listing
March 2012

Impact of tumor size on outcomes after anatomic lung resection for stage 1A non-small cell lung cancer based on the current staging system.

J Thorac Cardiovasc Surg 2012 Feb 9;143(2):390-7. Epub 2011 Dec 9.

Division of Thoracic and Foregut Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, Pa., USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtcvs.2011.10.023DOI Listing
February 2012

Doubling times and CT screen–detected lung cancers in the Pittsburgh Lung Screening Study.

Am J Respir Crit Care Med 2012 Jan;185(1):85-9

Department of Medicine, Heart, Lung and Esophageal Surgery Institute, University of Pittsuburgh, Pittsburgh, PA 15232, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.201107-1223OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262038PMC
January 2012

Increased levels of tumor-infiltrating lymphocytes are associated with improved recurrence-free survival in stage 1A non-small-cell lung cancer.

J Surg Res 2011 Nov 22;171(1):1-5. Epub 2011 Apr 22.

Division of Thoracic Surgery, Heart, Lung, and Esophageal Surgery Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15232, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jss.2011.03.068DOI Listing
November 2011

K-ras mutations in lung tumors from NNK-treated mice with lipopolysaccharide-elicited lung inflammation.

Anticancer Res 2011 Sep;31(9):2877-82

Environmental and Occupational Health, University of Pittsburgh, 100 Technology Drive, Bridgeside Point, Pittsburgh, PA 15219-3130, USA.

View Article

Download full-text PDF

Source
September 2011

Dual blockade of EGFR and c-Met abrogates redundant signaling and proliferation in head and neck carcinoma cells.

Clin Cancer Res 2011 Jul 27;17(13):4425-38. Epub 2011 May 27.

Department of Pharmacology & Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-10-3339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138116PMC
July 2011

Molecular analysis of plasma DNA for the early detection of lung cancer by quantitative methylation-specific PCR.

Clin Cancer Res 2010 Jul 30;16(13):3463-72. Epub 2010 Jun 30.

Department of Otolaryngology-Head and Neck Cancer Research Division, Johns Hopkins School of Medicine, Baltimore, Maryland 21231, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-09-3304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2899894PMC
July 2010

Early changes in pulmonary gene expression following tobacco exposure shed light on the role of estrogen metabolism in lung carcinogenesis.

Authors:
Jill M Siegfried

Cancer Prev Res (Phila) 2010 Jun 1;3(6):692-5. Epub 2010 Jun 1.

University of Pittsburgh Cancer Institute, Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pennsylvania, USA.

View Article

Download full-text PDF

Source
http://cancerpreventionresearch.aacrjournals.org/cgi/doi/10.
Publisher Site
http://dx.doi.org/10.1158/1940-6207.CAPR-10-0093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881174PMC
June 2010

Estrogen receptor signaling in lung cancer.

Semin Oncol 2009 Dec;36(6):524-31

Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15213, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00937754090018
Publisher Site
http://dx.doi.org/10.1053/j.seminoncol.2009.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818861PMC
December 2009

Fibulin-5 suppresses lung cancer invasion by inhibiting matrix metalloproteinase-7 expression.

Cancer Res 2009 Aug 7;69(15):6339-46. Epub 2009 Jul 7.

Department of Pharmacology and Chemical Biolog, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-09-0398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719681PMC
August 2009

Pilot study of gefitinib and fulvestrant in the treatment of post-menopausal women with advanced non-small cell lung cancer.

Lung Cancer 2009 Apr 12;64(1):51-9. Epub 2008 Aug 12.

University of Wisconsin Paul P. Carbone Comprehensive Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.lungcan.2008.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164240PMC
April 2009

Kinin b2 receptor mediates induction of cyclooxygenase-2 and is overexpressed in head and neck squamous cell carcinomas.

Mol Cancer Res 2008 Dec;6(12):1946-56

Department of Pharmacology and Chemical Biology, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15261, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1541-7786.MCR-07-2197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575100PMC
December 2008

The Pittsburgh Lung Screening Study (PLuSS): outcomes within 3 years of a first computed tomography scan.

Am J Respir Crit Care Med 2008 Nov 17;178(9):956-61. Epub 2008 Jul 17.

Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15232, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.200802-336OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720144PMC
November 2008

Association of radiographic emphysema and airflow obstruction with lung cancer.

Am J Respir Crit Care Med 2008 Oct 19;178(7):738-44. Epub 2008 Jun 19.

Division of Pulmonary Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.200803-435OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556456PMC
October 2008

Nicotine activates cell-signaling pathways through muscle-type and neuronal nicotinic acetylcholine receptors in non-small cell lung cancer cells.

Pulm Pharmacol Ther 2007 18;20(6):629-41. Epub 2006 Aug 18.

Department of Pharmacology, University of Pittsburgh, E1340 Biomedical Science Tower, Pittsburgh, PA 15213, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pupt.2006.07.001DOI Listing
January 2008

Downregulation of Dkk3 activates beta-catenin/TCF-4 signaling in lung cancer.

Carcinogenesis 2008 Jan 28;29(1):84-92. Epub 2007 Nov 28.

Department of Pharmacology.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/carcin/bgm267DOI Listing
January 2008

Signaling pathways involved in cyclooxygenase-2 induction by hepatocyte growth factor in non small-cell lung cancer.

Mol Pharmacol 2007 Sep 5;72(3):769-79. Epub 2007 Jun 5.

Department of Pharmacology, University of Pittsburgh, Pittsburgh, PA 15261, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1124/mol.107.034215DOI Listing
September 2007

Frequent inactivation of RAMP2, EFEMP1 and Dutt1 in lung cancer by promoter hypermethylation.

Clin Cancer Res 2007 Aug;13(15 Pt 1):4336-44

Department of Pharmacology, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-07-0015DOI Listing
August 2007

Association of the EGFR intron 1 CA repeat length with lung cancer risk.

Mol Carcinog 2007 May;46(5):372-80

Department of Pharmacology, University of Pittsburgh Cancer Institute, SPORE in Lung Cancer, University of Pittsburgh, Pittsburgh, Pennsylvania 15213-1863, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mc.20285DOI Listing
May 2007

Gastrin-releasing peptide activates Akt through the epidermal growth factor receptor pathway and abrogates the effect of gefitinib.

Exp Cell Res 2007 Apr 3;313(7):1361-72. Epub 2007 Feb 3.

Department of Pharmacology, University of Pittsburgh Cancer Institute, University of Pittsburgh, Lab 2.7, 5117 Centre Ave., Pittsburgh, PA 15213, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yexcr.2007.01.016DOI Listing
April 2007

Polymorphisms in DNA repair genes XPD and XRCC1 and p53 mutations in lung carcinomas of never-smokers.

Mol Carcinog 2006 Nov;45(11):828-32

Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15219, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mc.20208DOI Listing
November 2006

Mutation and polymorphism in the EGFR-TK domain associated with lung cancer.

J Thorac Oncol 2006 Sep;1(7):635-47

Department of Pharmacology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213-1863, USA.

View Article

Download full-text PDF

Source
September 2006

Transgenic mice overexpressing hepatocyte growth factor in the airways show increased susceptibility to lung cancer.

Carcinogenesis 2006 Aug 2;27(8):1547-55. Epub 2006 Mar 2.

Department of Pharmacology, University of Pittsburgh Cancer Institute, PA 15261, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/carcin/bgl003DOI Listing
August 2006

Non-small-cell lung cancer and breast carcinoma: chemotherapy and beyond.

Lancet Oncol 2006 May;7(5):416-24

Division of Hematology/Oncology, University of California, San Francisco, CA 94115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1470-2045(06)70693-3DOI Listing
May 2006

Hormone replacement therapy and decreased lung cancer survival.

Authors:
Jill M Siegfried

J Clin Oncol 2006 Jan 28;24(1):9-10. Epub 2005 Nov 28.

View Article

Download full-text PDF

Source
http://ascopubs.org/doi/10.1200/JCO.2005.04.2531
Publisher Site
http://dx.doi.org/10.1200/JCO.2005.04.2531DOI Listing
January 2006

Association of polymorphisms in the cyclin D1 and XPD genes and susceptibility to cancers of the upper aero-digestive tract.

Mol Carcinog 2005 Apr;42(4):222-8

Center for Clinical Pharmacology, Department of Medicine, University of Pittsburgh, 100 Technology Drive, Pittsburgh, PA 15219, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mc.20086DOI Listing
April 2005

Gastrin-releasing peptide receptor mediates activation of the epidermal growth factor receptor in lung cancer cells.

Neoplasia 2005 Apr;7(4):426-31

Department of Otolaryngology, University of Pittsburgh Medical Center and University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1501149PMC
http://dx.doi.org/10.1593/neo.04454DOI Listing
April 2005

Regulation of endogenous gene expression in human non-small cell lung cancer cells by estrogen receptor ligands.

Cancer Res 2005 Feb;65(4):1598-605

Department of Pharmacology, University of Pittsburgh and The University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA.

View Article

Download full-text PDF

Source
http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-04-2694DOI Listing
February 2005