Jiejun Wu

Jiejun Wu

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Jiejun Wu

Jiejun Wu

Publications by authors named "Jiejun Wu"

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Fluoro analogs of bioactive oxy-sterols: Synthesis of an EBI2 agonist with enhanced metabolic stability.

Bioorg Med Chem Lett 2016 10 12;26(20):4888-4891. Epub 2016 Sep 12.

Janssen Research & Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2016.09.029DOI Listing
October 2016

Large-roll growth of 25-inch hexagonal BN monolayer film for self-release buffer layer of free-standing GaN wafer.

Sci Rep 2016 10 19;6:34766. Epub 2016 Oct 19.

Fujian Key Laboratory of Semiconductor Materials and Applications, CI center for OSED, College of Physical Science and Technology, Xiamen University, Xiamen 361005, China.

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http://www.nature.com/articles/srep34766
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http://dx.doi.org/10.1038/srep34766DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069463PMC
October 2016

Phenotyping drug polypharmacology via eicosanoid profiling of blood.

J Lipid Res 2015 Aug 28;56(8):1492-500. Epub 2015 May 28.

Discovery Sciences Janssen Research & Development, LLC, San Diego, CA.

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http://dx.doi.org/10.1194/jlr.M058677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513990PMC
August 2015

Chromatographic separation of bioactive oxycholesterols by GC, HPLC and SFC.

Curr Top Med Chem 2012 ;12(11):1264-70

Community of Research Excellence & Advanced Technology (CREATe), Janssen Pharmaceutical Companies of Johnson and Johnson, Analytical Chemistry, 3210 Merryfield Row, San Diego, CA 92121, USA.

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http://dx.doi.org/10.2174/156802612800672880DOI Listing
March 2013

A highly efficient, high-throughput lipidomics platform for the quantitative detection of eicosanoids in human whole blood.

Anal Biochem 2013 Feb 26;433(2):181-8. Epub 2012 Oct 26.

Immunology Discovery, Janssen Research and Development, La Jolla, CA 92121, USA.

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http://dx.doi.org/10.1016/j.ab.2012.10.022DOI Listing
February 2013

Automatic analysis of quantitative NMR data of pharmaceutical compound libraries.

Anal Chem 2012 Aug 20;84(15):6914-8. Epub 2012 Jul 20.

Janssen Research & Development, 3210 Merryfield Row, San Diego, California 92121-1126, USA.

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http://dx.doi.org/10.1021/ac301544uDOI Listing
August 2012

Study of GPR81, the lactate receptor, from distant species identifies residues and motifs critical for GPR81 functions.

Mol Pharmacol 2011 Nov 23;80(5):848-58. Epub 2011 Aug 23.

Johnson and Johnson Pharmaceutical Research and Development, San Diego, CA 92121, USA.

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http://molpharm.aspetjournals.org/cgi/doi/10.1124/mol.111.07
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http://dx.doi.org/10.1124/mol.111.074500DOI Listing
November 2011

Direct, metal-free amination of heterocyclic amides/ureas with NH-heterocycles and N-substituted anilines in POCl3.

J Org Chem 2011 Oct 7;76(20):8262-9. Epub 2011 Sep 7.

Johnson & Johnson Pharmaceutical Research & Development, LLC, 3210 Merryfield Row, San Diego, California 92121, United States.

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http://dx.doi.org/10.1021/jo201425qDOI Listing
October 2011

Oxysterols direct B-cell migration through EBI2.

Nature 2011 Jul 27;475(7357):519-23. Epub 2011 Jul 27.

Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 3210 Merryfield Row, San Diego, California 92121, USA.

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http://dx.doi.org/10.1038/nature10226DOI Listing
July 2011

Comparing multiple ChIP-sequencing experiments.

J Bioinform Comput Biol 2011 Apr;9(2):269-82

Department of Biomedical Informatics, The Ohio State University , Columbus, OH, 43210, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289603PMC
April 2011

Genome-wide mapping of RNA Pol-II promoter usage in mouse tissues by ChIP-seq.

Nucleic Acids Res 2011 Jan 14;39(1):190-201. Epub 2010 Sep 14.

Center for Systems and Computational Biology, Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1093/nar/gkq775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017616PMC
January 2011

Inference of hierarchical regulatory network of estrogen-dependent breast cancer through ChIP-based data.

BMC Syst Biol 2010 Dec 17;4:170. Epub 2010 Dec 17.

Department of Biomedical Informatics, The Ohio State University, Columbus, USA.

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http://dx.doi.org/10.1186/1752-0509-4-170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012048PMC
December 2010

Comparative study on ChIP-seq data: normalization and binding pattern characterization.

Bioinformatics 2009 Sep 26;25(18):2334-40. Epub 2009 Jun 26.

Department of Molecular Virology, Immunology & Medical Genetics, Ohio State University, Columbus, OH 43210, USA.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btp384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800347PMC
September 2009

Lactate inhibits lipolysis in fat cells through activation of an orphan G-protein-coupled receptor, GPR81.

J Biol Chem 2009 Jan 1;284(5):2811-22. Epub 2008 Dec 1.

Johnson & Johnson Pharmaceutical Research & Development LLC, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1074/jbc.M806409200DOI Listing
January 2009

Thiadiazolopiperazinyl ureas as inhibitors of fatty acid amide hydrolase.

Bioorg Med Chem Lett 2008 Sep 25;18(17):4838-43. Epub 2008 Jul 25.

Johnson & Johnson Pharmaceutical Research and Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/j.bmcl.2008.07.081DOI Listing
September 2008

A Poisson mixture model to identify changes in RNA polymerase II binding quantity using high-throughput sequencing technology.

BMC Genomics 2008 Sep 16;9 Suppl 2:S23. Epub 2008 Sep 16.

Division of Biostatistics, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

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http://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2164-9-S2-S23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2559888PMC
September 2008

Applications of chromatin immunoprecipitation-based epigenomic tools in nutritional studies.

Nutr Rev 2008 Aug;66 Suppl 1:S49-53

The Human Cancer Genetics Program, Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1111/j.1753-4887.2008.00068.xDOI Listing
August 2008

Genome-wide analysis of alternative promoters of human genes using a custom promoter tiling array.

BMC Genomics 2008 Jul 25;9:349. Epub 2008 Jul 25.

Human Cancer Genetics Program, Comprehensive Cancer Center, Department of Molecular Virology, Immunology, and Medical Genetics, The Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.1186/1471-2164-9-349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527337PMC
July 2008

Application of calorimetry, sub-ambient atomic force microscopy and dynamic mechanical analysis to the study of frozen aqueous trehalose solutions.

Pharm Res 2008 Jun;25(6):1396-404

School of Chemical Sciences and Pharmacy, University of East Anglia, Norwich, Norfolk, NR4 7TJ, UK.

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http://dx.doi.org/10.1007/s11095-007-9530-yDOI Listing
June 2008

Synthesis and biological evaluation of diamine-based histamine H3 antagonists with serotonin reuptake inhibitor activity.

Bioorg Med Chem Lett 2007 Jun 15;17(11):3130-5. Epub 2007 Mar 15.

Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/j.bmcl.2007.03.034DOI Listing
June 2007

ChIP-chip comes of age for genome-wide functional analysis.

Cancer Res 2006 Jul;66(14):6899-902

Departments of Molecular Genetics and Molecular Virology, Immunology, and Medical Genetics, Division of Human Cancer Genetics, Comprehensive Cancer Center, Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-0276DOI Listing
July 2006

G-protein-coupled receptor (GPCR)-142 does not contribute to relaxin-3 binding in the mouse brain: further support that relaxin-3 is the physiological ligand for GPCR135.

Neuroendocrinology 2005 13;82(3-4):139-50. Epub 2006 Jan 13.

Johnson & Johnson Pharmaceutical Research & Development, LLC, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1159/000091267DOI Listing
June 2006

Stereoselective synthesis of Z-alpha-aryl-alpha,beta-unsaturated esters.

J Org Chem 2006 Jun;71(13):5039-42

Department of Drug Discovery, Johnson & Johnson Pharmaceutical Research and Development, L.L.C., 3210 Merryfield Row, San Diego, California 92121, USA.

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http://pubs.acs.org/doi/abs/10.1021/jo060586t
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http://dx.doi.org/10.1021/jo060586tDOI Listing
June 2006

INSL5 is a high affinity specific agonist for GPCR142 (GPR100).

J Biol Chem 2005 Jan 2;280(1):292-300. Epub 2004 Nov 2.

Johnson & Johnson Pharmaceutical Research and Development, San Diego, California 92121, USA.

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http://dx.doi.org/10.1074/jbc.M409916200DOI Listing
January 2005

Hold-and-flush, a novel fraction collection method in semi-preparative subcritical and supercritical fluid chromatography.

J Chromatogr A 2004 Jul;1042(1-2):169-72

Drug Discovery, Johnson and Johnson Pharmaceutical Research and Development, LLC, 3210 Merryfield Row, San Diego, CA 92121-1126, USA.

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http://dx.doi.org/10.1016/j.chroma.2004.05.037DOI Listing
July 2004

Exact mass measurement on an electrospray ionization time-of-flight mass spectrometer: error distribution and selective averaging.

J Mass Spectrom 2003 Oct;38(10):1043-53

Drug Discovery, Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121-1126, USA.

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http://doi.wiley.com/10.1002/jms.516
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http://dx.doi.org/10.1002/jms.516DOI Listing
October 2003