Publications by authors named "Jiehui Deng"

28Publications

Serial single-cell profiling analysis of metastatic TNBC during Nab-paclitaxel and pembrolizumab treatment.

Breast Cancer Res Treat 2020 Sep 19. Epub 2020 Sep 19.

Division of Hematology and Medical Oncology, Laura and Isaac Perlmutter Cancer Center, New York University Langone Medical Center, New York, NY, USA.

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http://dx.doi.org/10.1007/s10549-020-05936-4DOI Listing
September 2020

Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer.

Cell Rep 2019 04;27(3):806-819.e5

Ludwig Collaborative and Swim Across America Laboratory, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Parker Institute for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Weill Cornell Medicine, New York, NY 10065, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247193039
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http://dx.doi.org/10.1016/j.celrep.2019.03.066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719696PMC
April 2019

Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms.

Cancer Discov 2018 03 9;8(3):276-287. Epub 2018 Jan 9.

Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/2159-8290.CD-17-0952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835190PMC
March 2018

Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids.

Cancer Discov 2018 02 3;8(2):196-215. Epub 2017 Nov 3.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1158/2159-8290.CD-17-0833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809290PMC
February 2018

STAT3 in CD8+ T Cells Inhibits Their Tumor Accumulation by Downregulating CXCR3/CXCL10 Axis.

Cancer Immunol Res 2015 Aug 29;3(8):864-870. Epub 2015 May 29.

Department of Cancer Immunotherapeutics and Tumor Immunology, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1158/2326-6066.CIR-15-0014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527884PMC
August 2015

CD8+ T-cell immunosurveillance constrains lymphoid premetastatic myeloid cell accumulation.

Eur J Immunol 2015 Jan 10;45(1):71-81. Epub 2014 Nov 10.

Department of Cancer Immunotherapeutics and Tumor Immunology, Beckman Research Institute and City of Hope Comprehensive Cancer Center, Duarte, CA, USA.

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http://dx.doi.org/10.1002/eji.201444467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293284PMC
January 2015

S1PR1 is crucial for accumulation of regulatory T cells in tumors via STAT3.

Cell Rep 2014 Mar 13;6(6):992-999. Epub 2014 Mar 13.

Department of Cancer Immunotherapeutics and Tumor Immunology, Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247140011
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http://dx.doi.org/10.1016/j.celrep.2014.02.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988983PMC
March 2014

Icaritin inhibits JAK/STAT3 signaling and growth of renal cell carcinoma.

PLoS One 2013 6;8(12):e81657. Epub 2013 Dec 6.

Genetic Engineering International Cooperation Base of Chinese Ministry of Science and Technology, Key Laboratory of Molecular Biophysics of Chinese Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology (HUST), Wuhan, Hubei, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0081657PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855768PMC
September 2014

B cells promote tumor progression via STAT3 regulated-angiogenesis.

PLoS One 2013 29;8(5):e64159. Epub 2013 May 29.

Department of Cancer Immunotherapeutics and Tumor Immunology, Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, California, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0064159PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667024PMC
January 2014

G-protein-coupled receptor agonist BV8/prokineticin-2 and STAT3 protein form a feed-forward loop in both normal and malignant myeloid cells.

J Biol Chem 2013 May 2;288(19):13842-9. Epub 2013 Apr 2.

Departments of Cancer Immunotherapeutics and Tumor Immunology, Beckman Research Institute, City of Hope National Medical Center, Duarte, California 91010, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M113.450049
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http://dx.doi.org/10.1074/jbc.M113.450049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650420PMC
May 2013

Prognostic significance of B-cells and pSTAT3 in patients with ovarian cancer.

PLoS One 2013 10;8(1):e54029. Epub 2013 Jan 10.

Department of Cancer Immunotherapeutics and Tumor Immunology, Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0054029PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542323PMC
July 2013

S1PR1 is an effective target to block STAT3 signaling in activated B cell-like diffuse large B-cell lymphoma.

Blood 2012 Aug 28;120(7):1458-65. Epub 2012 Jun 28.

Departments of Cancer Immunotherapeutics and Tumor Immunology, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1182/blood-2011-12-399030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423784PMC
August 2012

S1PR1-STAT3 signaling is crucial for myeloid cell colonization at future metastatic sites.

Cancer Cell 2012 May;21(5):642-54

Department of Cancer Immunotherapeutics and Tumor Immunology, Beckman Research Institute and City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1016/j.ccr.2012.03.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360884PMC
May 2012

A requirement of STAT3 DNA binding precludes Th-1 immunostimulatory gene expression by NF-κB in tumors.

Cancer Res 2011 Jun 18;71(11):3772-80. Epub 2011 Apr 18.

Department of Cancer Immunotherapeutics and Tumor Immunology, Beckman Research Institute, City of Hope National Medical Center, Duarte, California 91010, USA.

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http://cancerres.aacrjournals.org/content/71/11/3772.full.pd
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
Publisher Site
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107358PMC
http://dx.doi.org/10.1158/0008-5472.CAN-10-3304DOI Listing
June 2011

Targeting STAT3 in adoptively transferred T cells promotes their in vivo expansion and antitumor effects.

Cancer Res 2010 Dec 30;70(23):9599-610. Epub 2010 Nov 30.

Department of Cancer Immunotherapeutics & Tumor Immunology, Beckman Research Institute at City of Hope, Duarte, California, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-10-1293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017475PMC
December 2010

STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors.

Nat Med 2010 Dec 21;16(12):1421-8. Epub 2010 Nov 21.

Department of Cancer Immunotherapeutics and Tumor Immunology, Beckman Research Institute and City of Hope Comprehensive Cancer Center, Duarte, California, USA.

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http://dx.doi.org/10.1038/nm.2250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088498PMC
December 2010

Targeting Stat3 in the myeloid compartment drastically improves the in vivo antitumor functions of adoptively transferred T cells.

Cancer Res 2010 Oct 14;70(19):7455-64. Epub 2010 Sep 14.

Department of Cancer Immunotherapeutics and Tumor Immunology, Beckman Research Institute, City of Hope National Medical Center, Duarte, California 91010-3000, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-0736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058618PMC
October 2010