Jiaoti Huang

Jiaoti Huang

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Jiaoti Huang

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Prostate Cancer Detection Rate of Free-hand versus 3D Template Mapping Biopsy Using an MRI/Ultrasound Fusion Device in Biopsy-Naïve Men.

J Urol 2019 Oct 9:101097JU0000000000000587. Epub 2019 Oct 9.

Department of Bioengineering, University of California, Los Angeles.

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http://dx.doi.org/10.1097/JU.0000000000000587DOI Listing
October 2019

Molecular determinants for enzalutamide-induced transcription in prostate cancer.

Nucleic Acids Res 2019 Sep 10. Epub 2019 Sep 10.

Department of Pathology, Duke University School of Medicine, Durham, NC 27710, USA.

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http://dx.doi.org/10.1093/nar/gkz790DOI Listing
September 2019

The size of cell-free mitochondrial DNA in blood is inversely correlated with tumor burden in cancer patients.

Precis Clin Med 2019 Sep 1;2(3):131-139. Epub 2019 Oct 1.

Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1093/pcmedi/pbz014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770274PMC
September 2019

The expanded role of fatty acid metabolism in cancer: new aspects and targets.

Precis Clin Med 2019 Sep 1;2(3):183-191. Epub 2019 Oct 1.

Department of Pathology, Duke University School of Medicine, Duke Cancer Institute, Duke University, Durham, NC 27514, USA.

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http://dx.doi.org/10.1093/pcmedi/pbz017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770278PMC
September 2019

RNA Splicing of the BHC80 Gene Contributes to Neuroendocrine Prostate Cancer Progression.

Eur Urol 2019 Aug 23;76(2):157-166. Epub 2019 Mar 23.

Vancouver Prostate Centre, Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03022838193019
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http://dx.doi.org/10.1016/j.eururo.2019.03.011DOI Listing
August 2019

Therapeutic potential of ReACp53 targeting mutant p53 protein in CRPC.

Prostate Cancer Prostatic Dis 2019 Aug 30. Epub 2019 Aug 30.

Department of Pathology, Duke University Medicine, Durham, NC, USA.

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http://dx.doi.org/10.1038/s41391-019-0172-zDOI Listing
August 2019

Pan-cancer Convergence to a Small-Cell Neuroendocrine Phenotype that Shares Susceptibilities with Hematological Malignancies.

Cancer Cell 2019 Jul;36(1):17-34.e7

Department of Molecular and Medical Pharmacology, UCLA, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, CA 90095, USA; Crump Institute for Molecular Imaging, UCLA, Los Angeles, CA 90095, USA; California NanoSystems Institute, UCLA, Los Angeles, CA 90095, USA; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, UCLA, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703903PMC
July 2019

Making a Tissue Microarray.

Methods Mol Biol 2019 ;1897:313-323

Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

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http://dx.doi.org/10.1007/978-1-4939-8935-5_27DOI Listing
June 2019

Predicting clinical outcome of therapy-resistant prostate cancer.

Authors:
Xin Ma Jiaoti Huang

Proc Natl Acad Sci U S A 2019 Jun 21;116(23):11090-11092. Epub 2019 May 21.

Department of Pathology, Duke University School of Medicine, Durham, NC 27710

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http://dx.doi.org/10.1073/pnas.1906812116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561261PMC
June 2019

Correction to: N-Myc promotes therapeutic resistance development of neuroendocrine prostate cancer by differentially regulating miR-421/ ATM pathway.

Mol Cancer 2019 Jun 19;18(1):107. Epub 2019 Jun 19.

Department of Pathology, Duke Unversity School of Medicine, DUMC box 103864, 905 S. Lasalle Street, Durham, NC, 27710, USA.

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http://dx.doi.org/10.1186/s12943-019-1034-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582568PMC
June 2019

DHX15 is up-regulated in castration-resistant prostate cancer and required for androgen receptor sensitivity to low DHT concentrations.

Prostate 2019 May 3;79(6):657-666. Epub 2019 Feb 3.

Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1002/pros.23773DOI Listing
May 2019

Prostate cancer: molecular and cellular mechanisms and their implications in therapy resistance and disease progression.

Asian J Androl 2019 May-Jun;21(3):213-214

Department of Pathology, Duke University School of Medicine, Durham, NC 27514, USA.

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http://dx.doi.org/10.4103/aja.aja_31_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498730PMC
April 2019

Reply to A. Dalla Volta et al.

J Clin Oncol 2019 Feb 17;37(4):351-352. Epub 2018 Dec 17.

Rahul Aggarwal, MD, University of California San Francisco, San Francisco, CA; Jiaoti Huang, MD, PhD, Duke University, Durham, NC; Joshi Alumkal, MD, Oregon Health Sciences University, Portland, OR; Felix Y. Feng, MD and Li Zhang, PhD, University of California San Francisco, San Francisco, CA; Joshua M. Stuart, PhD, University of California Santa Cruz, Santa Cruz, CA; and Eric J. Small, MD, University of California San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1200/JCO.18.01487DOI Listing
February 2019

SRRM4 gene expression correlates with neuroendocrine prostate cancer.

Prostate 2019 01 28;79(1):96-104. Epub 2018 Aug 28.

Vancouver Prostate Centre, Department of Urologic Sciences, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1002/pros.23715DOI Listing
January 2019

Androgen deprivation-induced ZBTB46-PTGS1 signaling promotes neuroendocrine differentiation of prostate cancer.

Cancer Lett 2019 01 9;440-441:35-46. Epub 2018 Oct 9.

Graduate Institute of Molecular Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan; TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2018.10.004DOI Listing
January 2019

ATM deficiency promotes progression of CRPC by enhancing Warburg effect.

Endocr Relat Cancer 2019 01;26(1):59-71

Department of Pathology, Duke University School of Medicine, Durham, North Carolina, USA.

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https://erc.bioscientifica.com/view/journals/erc/26/1/ERC-18
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http://dx.doi.org/10.1530/ERC-18-0196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226046PMC
January 2019

N-Myc promotes therapeutic resistance development of neuroendocrine prostate cancer by differentially regulating miR-421/ATM pathway.

Mol Cancer 2019 01 18;18(1):11. Epub 2019 Jan 18.

Department of Pathology, Duke Unversity School of Medicine, DUMC box 103864, 905 S. Lasalle Street, Durham, NC, 27710, USA.

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http://dx.doi.org/10.1186/s12943-019-0941-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337850PMC
January 2019

Targeting androgen receptor-independent pathways in therapy-resistant prostate cancer.

Asian J Urol 2019 Jan 28;6(1):91-98. Epub 2018 Nov 28.

Department of Pathology, Duke University School of Medicine, Durham, NC, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S22143882183009
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http://dx.doi.org/10.1016/j.ajur.2018.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363598PMC
January 2019

The promise of immunotherapy in genitourinary malignancies.

Precis Clin Med 2018 Dec 19;1(3):97-101. Epub 2018 Dec 19.

Duke Cancer Institute, Duke University School of Medicine, Durham, NC.

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https://academic.oup.com/pcm/article/1/3/97/5253459
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http://dx.doi.org/10.1093/pcmedi/pby018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333044PMC
December 2018

Receptor activator of NF-κB (RANK)-mediated induction of metastatic spread and association with poor prognosis in renal cell carcinoma.

Urol Oncol 2018 11 28;36(11):502.e15-502.e24. Epub 2018 Aug 28.

Department of Urology, University Medicine at the Ernst-Moritz-Arndt University Greifswald, Greifswald, Germany; Institute of Urologic Oncology, Department of Urology, David Geffen School of Medicine at the University of California, Los Angeles, CA; Institute of Medical Biochemistry and Molecular Medicine, University Medicine at the Ernst-Moritz-Arndt University Greifswald, Greifswald, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.urolonc.2018.07.013DOI Listing
November 2018

Three-dimensional localization and targeting of prostate cancer foci with imaging and histopathologic correlation: establishing a multidisciplinary team for quality improvement.

Curr Opin Urol 2018 11;28(6):506-511

Division of Urological Surgery, Duke University Medical Center, Duke Cancer Institute, Durham, NC.

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http://dx.doi.org/10.1097/MOU.0000000000000554DOI Listing
November 2018

A Human Adult Stem Cell Signature Marks Aggressive Variants across Epithelial Cancers.

Cell Rep 2018 09;24(12):3353-3366.e5

Department of Molecular and Medical Pharmacology, UCLA, Los Angeles, CA 90095, USA; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, UCLA, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, CA 90095, USA; Crump Institute for Molecular Imaging, UCLA, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.08.062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382070PMC
September 2018

Clinical and Genomic Characterization of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer: A Multi-institutional Prospective Study.

J Clin Oncol 2018 08 9;36(24):2492-2503. Epub 2018 Jul 9.

Rahul Aggarwal, Li Zhang, Felix Y. Feng, Paul Lloyd, Jack Youngren, Adam Foye, Denise Playdle, Charles J. Ryan, and Eric J. Small, University of California San Francisco, San Francisco; Alana S. Weinstein, Verena Friedl, Can Zhang, Christopher K. Wong, Vlado Uzunangelov, Artem Sokolov, Yulia Newton, and Joshua M. Stuart, University of California Santa Cruz, Santa Cruz; Owen N. Witte and Matthew Rettig, University of California Los Angeles, Los Angeles; Christopher P. Evans and Primo Lara, University of California Davis, Davis, CA; Jiaoti Huang, Duke University, Durham, NC; Joshi J. Alumkal, George V. Thomas, and Tomasz M. Beer, Oregon Health Sciences University, Portland, OR; Martin Gleave and Kim N. Chi, University of British Columbia, Vancouver, British Columbia, Canada; Lawrence True, University of Washington, Seattle, WA; Himisha Beltran and Mark A. Rubin, Weill Cornell Medicine, New York, NY; and Francesca Demichelis, University of Trento, Trento, Italy.

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http://dx.doi.org/10.1200/JCO.2017.77.6880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366813PMC
August 2018

Multiparametric Prostate MR Imaging: Impact on Clinical Staging and Decision Making.

Urol Clin North Am 2018 Aug;45(3):455-466

Department of Radiology, Duke University Medical Center, DUMC Box 3808, Durham, NC 27710, USA; Division of Urologic Surgery, Department of Surgery, Duke Prostate Center, Duke University Medical Center, DUMC Box 2804, Durham, NC 27710, USA; Duke Cancer Institute, DUMC Box 3917, Durham, NC 27710, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ucl.2018.03.010DOI Listing
August 2018

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.

Cell 2018 07 19;174(3):758-769.e9. Epub 2018 Jul 19.

Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco (UCSF), San Francisco, CA, USA; Division of Hematology and Oncology, Department of Medicine, UCSF, San Francisco, CA, USA; Department of Radiation Oncology, UCSF, San Francisco, CA, USA; Department of Urology, UCSF, San Francisco, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.06.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425931PMC
July 2018

Multiparametric Prostate MR Imaging: Impact on Clinical Staging and Decision Making.

Radiol Clin North Am 2018 Mar 11;56(2):239-250. Epub 2017 Dec 11.

Department of Radiology, Duke University Medical Center, DUMC Box 3808, Durham, NC 27710, USA; Division of Urologic Surgery, Department of Surgery, Duke Prostate Center, Duke University Medical Center, DUMC Box 2804, Durham, NC 27710, USA; Duke Cancer Institute, DUMC Box 3917, Durham, NC 27710, USA. Electronic address:

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http://dx.doi.org/10.1016/j.rcl.2017.10.007DOI Listing
March 2018

Focal Therapy Eligibility Determined by Magnetic Resonance Imaging/Ultrasound Fusion Biopsy.

J Urol 2018 02 19;199(2):453-458. Epub 2017 Aug 19.

Department of Urology, David Geffen School of Medicine, Los Angeles, California; Department of Bioengineering, University of California-Los Angeles, Los Angeles, California. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2017.08.085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780241PMC
February 2018

Value of Tracking Biopsy in Men Undergoing Active Surveillance of Prostate Cancer.

J Urol 2018 01 18;199(1):98-105. Epub 2017 Jul 18.

Department of Urology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2017.07.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760302PMC
January 2018

FOXA2 is a sensitive and specific marker for small cell neuroendocrine carcinoma of the prostate.

Mod Pathol 2017 09 16;30(9):1262-1272. Epub 2017 Jun 16.

Department of Pathology, Duke University School of Medicine, Durham, NC, USA.

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http://dx.doi.org/10.1038/modpathol.2017.44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330177PMC
September 2017

CT-Guided Bone Biopsies in Metastatic Castration-Resistant Prostate Cancer: Factors Predictive of Maximum Tumor Yield.

J Vasc Interv Radiol 2017 Aug 24;28(8):1073-1081.e1. Epub 2017 May 24.

Department of Radiology and Biomedical Imaging, University of California, San Francisco, 513 Parnassus Avenue, S-261, San Francisco, CA 94143-0628.

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http://dx.doi.org/10.1016/j.jvir.2017.04.019DOI Listing
August 2017

Loss of SPDEF and gain of TGFBI activity after androgen deprivation therapy promote EMT and bone metastasis of prostate cancer.

Sci Signal 2017 Aug 15;10(492). Epub 2017 Aug 15.

Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.

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http://dx.doi.org/10.1126/scisignal.aam6826DOI Listing
August 2017

Alternative Splicing of EZH2 pre-mRNA by SF3B3 Contributes to the Tumorigenic Potential of Renal Cancer.

Clin Cancer Res 2017 07 22;23(13):3428-3441. Epub 2016 Nov 22.

Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-2020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440213PMC
July 2017

Multiregional Radiogenomic Assessment of Prostate Microenvironments with Multiparametric MR Imaging and DNA Whole-Exome Sequencing of Prostate Glands with Adenocarcinoma.

Radiology 2017 07 28;284(1):109-119. Epub 2017 Apr 28.

From the Departments of Radiological Sciences (N.J., S.R., M.D.K.) and Urology (R.E.R.), University of California, Los Angeles-David Geffen School of Medicine, 10833 LeConte Ave, Box 951721, CHS 17-135, Los Angeles, CA 90095-1721; Department of Radiology, Weill Cornell Imaging, New York-Presbyterian Hospital, New York, NY (D.J.M.); Department of Pathology, Duke University School of Medicine, Durham, NC (J.H.); and College of Electrical and Computer Engineering, National Chiao Tung University, HsinChu, Taiwan (M.D.K.).

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http://dx.doi.org/10.1148/radiol.2017162827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197054PMC
July 2017

UDP-glucuronosyltransferases and biochemical recurrence in prostate cancer progression.

BMC Cancer 2017 Jul 3;17(1):463. Epub 2017 Jul 3.

Cedars-Sinai Health System, Center for Integrated Research on Cancer and Lifestyle, Cancer Genetics and Prevention Program, Surgery, 8700 Beverly Blvd, Los Angeles, CA, 90048, USA.

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http://dx.doi.org/10.1186/s12885-017-3463-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496250PMC
July 2017

Adrenal Teratoma: a Case Series and Review of the Literature.

Endocr Pathol 2017 Jun;28(2):152-158

Section of Endocrine Surgery, UCLA David Geffen School of Medicine, 10833 Le Conte Ave, 72-228 CHS, Los Angeles, CA, 90095, USA.

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http://dx.doi.org/10.1007/s12022-017-9468-5DOI Listing
June 2017

Targeted Biopsy to Detect Gleason Score Upgrading during Active Surveillance for Men with Low versus Intermediate Risk Prostate Cancer.

J Urol 2017 03 14;197(3 Pt 1):632-639. Epub 2016 Sep 14.

Department of Urology (NN, SN, DSS, LSM), University of California-Los Angeles, Los Angeles, California; Department of Radiology (DJM), University of California-Los Angeles, Los Angeles, California; Department of Biomedical Engineering (SN), University of California-Los Angeles, Los Angeles, California; Department of Pathology, Duke University School of Medicine (JH), Durham, North Carolina. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2016.09.070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315577PMC
March 2017

Magnetic Resonance Imaging Underestimation of Prostate Cancer Geometry: Use of Patient Specific Molds to Correlate Images with Whole Mount Pathology.

J Urol 2017 02 30;197(2):320-326. Epub 2016 Jul 30.

Department of Urology, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2016.07.084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540646PMC
February 2017

Alternative Splicing Provides a Novel Molecular Mechanism for Prostatic Small-cell Neuroendocrine Carcinoma.

Eur Urol 2017 01 29;71(1):79-80. Epub 2016 Jul 29.

Department of Pathology, Duke University School of Medicine, Durham, NC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2016.07.046DOI Listing
January 2017

Epidermal growth factor receptor signaling promotes metastatic prostate cancer through microRNA-96-mediated downregulation of the tumor suppressor ETV6.

Cancer Lett 2017 01 13;384:1-8. Epub 2016 Oct 13.

Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03043835163062
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http://dx.doi.org/10.1016/j.canlet.2016.10.014DOI Listing
January 2017

Molecular Signature to Risk-Stratify Prostate Cancer of Intermediate Risk.

Clin Cancer Res 2017 Jan 1;23(1):6-8. Epub 2016 Nov 1.

Department of Pathology, Duke University School of Medicine, Durham, North Carolina.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-2400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215130PMC
January 2017

Gli Transcription Factors Mediate the Oncogenic Transformation of Prostate Basal Cells Induced by a Kras-Androgen Receptor Axis.

J Biol Chem 2016 Dec 19;291(49):25749-25760. Epub 2016 Oct 19.

From the Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, Georgia 30602,

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http://dx.doi.org/10.1074/jbc.M116.753129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207270PMC
December 2016

Low CD38 Identifies Progenitor-like Inflammation-Associated Luminal Cells that Can Initiate Human Prostate Cancer and Predict Poor Outcome.

Cell Rep 2016 12;17(10):2596-2606

Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA 90095, USA; Urology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367888PMC
December 2016

Synthesis of IR-780 dye-conjugated abiraterone for prostate cancer imaging and therapy.

Int J Oncol 2016 Nov 16;49(5):1911-1920. Epub 2016 Sep 16.

Department of Urology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, P.R. China.

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http://dx.doi.org/10.3892/ijo.2016.3693DOI Listing
November 2016

Activation of Notch1 synergizes with multiple pathways in promoting castration-resistant prostate cancer.

Proc Natl Acad Sci U S A 2016 10 30;113(42):E6457-E6466. Epub 2016 Sep 30.

Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA 90095; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, CA 90095; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, CA 90095; Howard Hughes Medical Institute, University of California, Los Angeles, CA 90095

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http://dx.doi.org/10.1073/pnas.1614529113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081658PMC
October 2016

Carbohydrate Microarrays Identify Blood Group Precursor Cryptic Epitopes as Potential Immunological Targets of Breast Cancer.

J Immunol Res 2015 11;2015:510810. Epub 2015 Oct 11.

Department of Pathology, David Geffen School of Medicine, University of California in Los Angeles, 570 Westwood Plaza, Los Angeles, CA 90095, USA.

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http://downloads.hindawi.com/journals/jir/2015/510810.pdf
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http://www.hindawi.com/journals/jir/2015/510810/
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http://dx.doi.org/10.1155/2015/510810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619957PMC
August 2016

Focal Laser Ablation of Prostate Cancer: Phase I Clinical Trial.

J Urol 2016 07 31;196(1):68-75. Epub 2015 Dec 31.

Department of Urology, University of California, Los Angeles, Los Angeles, California; Center for Advanced Surgical and Interventional Technology, University of California, Los Angeles, Los Angeles, California. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2015.12.083DOI Listing
July 2016

Serial Magnetic Resonance Imaging in Active Surveillance of Prostate Cancer: Incremental Value.

J Urol 2016 May 7;195(5):1421-1427. Epub 2015 Dec 7.

Department of Urology, David Geffen School of Medicine, Los Angeles, California. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2015.11.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900685PMC
May 2016

The Role of CD44 in Glucose Metabolism in Prostatic Small Cell Neuroendocrine Carcinoma.

Mol Cancer Res 2016 Apr 1;14(4):344-53. Epub 2016 Feb 1.

Departments of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California.

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http://dx.doi.org/10.1158/1541-7786.MCR-15-0466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834240PMC
April 2016

Prostate epithelial cell of origin determines cancer differentiation state in an organoid transformation assay.

Proc Natl Acad Sci U S A 2016 Apr 4;113(16):4482-7. Epub 2016 Apr 4.

Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA 90095; Molecular Biology Institute, David Geffen School of Medicine, University of California, Los Angeles, CA 90095; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, CA 90095; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095; Howard Hughes Medical Institute, University of California, Los Angeles, CA 90095

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http://dx.doi.org/10.1073/pnas.1603645113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843433PMC
April 2016

N-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells.

Cancer Cell 2016 Apr 31;29(4):536-547. Epub 2016 Mar 31.

Department of Microbiology, Immunology, and Medical Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA 90095, USA; Howard Hughes Medical Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829466PMC
April 2016

Prostate cancer detection with magnetic resonance-ultrasound fusion biopsy: The role of systematic and targeted biopsies.

Cancer 2016 Mar 7;122(6):884-92. Epub 2016 Jan 7.

Department of Urology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California.

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http://dx.doi.org/10.1002/cncr.29874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777653PMC
March 2016

All-trans retinoic acids induce differentiation and sensitize a radioresistant breast cancer cells to chemotherapy.

BMC Complement Altern Med 2016 Mar 31;16:113. Epub 2016 Mar 31.

Department of Pathology and Laboratory Medicine, University of California, Los Angeles, USA.

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http://dx.doi.org/10.1186/s12906-016-1088-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815257PMC
March 2016

Functional screen identifies kinases driving prostate cancer visceral and bone metastasis.

Proc Natl Acad Sci U S A 2016 Jan 30;113(2):E172-81. Epub 2015 Nov 30.

Molecular Biology Institute, University of California, Los Angeles, CA 90095; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA 90095; Howard Hughes Medical Institute, University of California, Los Angeles, CA 90095; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, CA 90095; David Geffen School of Medicine, University of California, Los Angeles, CA 90095; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, CA 90095

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http://dx.doi.org/10.1073/pnas.1521674112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720329PMC
January 2016

Redefining the Autonomic Nerve Distribution of the Bladder Using 3-Dimensional Image Reconstruction.

J Urol 2015 Dec 21;194(6):1661-7. Epub 2015 May 21.

Department of Urology, University of California-Irvine, Orange, California. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2015.05.077DOI Listing
December 2015

Exploring Glycan Markers for Immunotyping and Precision-targeting of Breast Circulating Tumor Cells.

Arch Med Res 2015 Nov 1;46(8):642-50. Epub 2015 Dec 1.

SRI International Biosciences Division, Menlo Park, California, USA.

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http://dx.doi.org/10.1016/j.arcmed.2015.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729604PMC
November 2015

SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression.

Mol Cell 2015 Sep 3;59(6):917-30. Epub 2015 Sep 3.

Department of Pathology, Cancer Research Institute, Beth Israel Deaconess Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2015.07.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575912PMC
September 2015

Ligand-dependent genomic function of glucocorticoid receptor in triple-negative breast cancer.

Nat Commun 2015 Sep 16;6:8323. Epub 2015 Sep 16.

Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, Ohio State University College of Medicine, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1038/ncomms9323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573460PMC
September 2015

EGF Receptor Promotes Prostate Cancer Bone Metastasis by Downregulating miR-1 and Activating TWIST1.

Cancer Res 2015 Aug 12;75(15):3077-86. Epub 2015 Jun 12.

Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-3380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909124PMC
August 2015

Patients with Biopsy Gleason 9 and 10 Prostate Cancer Have Significantly Worse Outcomes Compared to Patients with Gleason 8 Disease.

J Urol 2015 Jul 24;194(1):91-7. Epub 2015 Jan 24.

Division of Hematology and Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1016/j.juro.2015.01.078DOI Listing
July 2015

Functional expression of sodium-glucose transporters in cancer.

Proc Natl Acad Sci U S A 2015 Jul 13;112(30):E4111-9. Epub 2015 Jul 13.

Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095-1751;

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http://dx.doi.org/10.1073/pnas.1511698112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522748PMC
July 2015

Elevated circulating tissue inhibitor of metalloproteinase 1 (TIMP-1) levels are associated with neuroendocrine differentiation in castration resistant prostate cancer.

Prostate 2015 May 5;75(6):616-27. Epub 2015 Jan 5.

Division of Hematology and Medical Oncology, The Tisch Cancer Institute, Mount Sinai School of Medicine, New York, New York.

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http://dx.doi.org/10.1002/pros.22945DOI Listing
May 2015

Loss of MyD88 leads to more aggressive TRAMP prostate cancer and influences tumor infiltrating lymphocytes.

Prostate 2015 Apr 16;75(5):463-73. Epub 2015 Jan 16.

Molecular Biology Institute, UCLA, Los Angeles, California.

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http://dx.doi.org/10.1002/pros.22932DOI Listing
April 2015

Neuroendocrine differentiation in prostate cancer: a mechanism of radioresistance and treatment failure.

Front Oncol 2015 14;5:90. Epub 2015 Apr 14.

Department of Pathology, David Geffen School of Medicine at UCLA , Los Angeles, CA , USA.

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http://dx.doi.org/10.3389/fonc.2015.00090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396194PMC
April 2015

p53 Mutation Directs AURKA Overexpression via miR-25 and FBXW7 in Prostatic Small Cell Neuroendocrine Carcinoma.

Mol Cancer Res 2015 Mar 15;13(3):584-91. Epub 2014 Dec 15.

Department of Pathology and Urology, Jonsson Comprehensive Cancer Center and Broad Center of Regenerative Medicine and Stem Cell Research, UCLA David Geffen School of Medicine, Los Angeles, California.

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http://dx.doi.org/10.1158/1541-7786.MCR-14-0277-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369163PMC
March 2015

CSF1 receptor targeting in prostate cancer reverses macrophage-mediated resistance to androgen blockade therapy.

Cancer Res 2015 Mar 3;75(6):950-62. Epub 2015 Mar 3.

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California. Department of Urology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.

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http://cancerres.aacrjournals.org/content/early/2015/03/03/0
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http://dx.doi.org/10.1158/0008-5472.CAN-14-0992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359956PMC
March 2015

Agonist and antagonist switch DNA motifs recognized by human androgen receptor in prostate cancer.

EMBO J 2015 Feb 22;34(4):502-16. Epub 2014 Dec 22.

Department of Molecular Virology, Immunology and Medical Genetics and the Comprehensive Cancer Center, The Ohio State University College of Medicine, Columbus, OH, USA

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http://dx.doi.org/10.15252/embj.201490306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331004PMC
February 2015