Publications by authors named "Jiaojiao Xue"

3 Publications

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Ginseng in vascular dysfunction: A review of therapeutic potentials and molecular mechanisms.

Phytother Res 2022 Jan 13. Epub 2022 Jan 13.

Jilin Ginseng Academy, Key Laboratory of Active Substances and Biological Mechanisms of Ginseng Efficacy, Ministry of Education, Jilin Provincial Key Laboratory of Bio-Macromolecules of Chinese Medicine, Changchun University of Chinese Medicine, Changchun, China.

Vascular dysfunction can lead to a variety of fatal diseases, including cardiovascular and cerebrovascular diseases, metabolic syndrome, and cancer. Although a large number of studies have reported the therapeutic effects of natural compounds on vascular-related diseases, ginseng is still the focus of research. Ginseng and its active substances have bioactive effects against different diseases with vascular dysfunction. In this review, we summarized the key molecular mechanisms and signaling pathways of ginseng, its different active ingredients or formula in the prevention and treatment of vascular-related diseases, including cardiac-cerebral vascular diseases, hypertension, diabetes complications, and cancer. Moreover, the bidirectional roles of ginseng in promoting or inhibiting angiogenesis have been highlighted. We systematically teased out the relationship between ginseng and vascular dysfunction, which could provide a basis for the clinical application of ginseng in the future.
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January 2022

Deep desulfurization performance of thiophene with deep eutectic solvents loaded carbon nanotube composites.

R Soc Open Sci 2021 Apr 21;8(4):201736. Epub 2021 Apr 21.

Dalian University, Dalian 116622 People's Republic of China.

One source of air pollution is the combustion of sulfur compounds in fuel oil. Reducing sulfur content in fuel oil has become a hot issue demanding timely solutions. Using ionic liquids and deep eutectic solvents (DESs) to remove sulfides in fuel oil has achieved good results presently. However, since DESs are liquid and their transportation and separation are inconvenient, a new way is proposed that the DESs are loaded on the carbon nanotubes (CNTs) with large specific surface area and good chemical stability. A series of composites materials (DESs/CNTs) were prepared. Finally, they are applied to the removal of sulfides in fuel oil. This loading method, which imparts introduced unique physico-chemical properties of the DESs to the carrier materials, preserves both advantages while overcoming some of the problems with DESs. The interaction between DESs and CNTs is mutual promotion. Therefore, this study has important theoretical significance and industrial application value. Under optimal conditions, when the reagent ChCl/p-TsOH (1 : 2) was loaded on multi-walled CNTs (OD = 30-60 nm) to prepare the composite material (ChCl/p-TsOH)/CNTs, the single desulfurization rate of the composite material was 95.8%. Finally, the catalytic/oxidation mechanism was studied systematically and this work would provide a green route for the desulfurization of fuels.
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April 2021

Clinical evaluation of a toothpaste containing lysozyme for removal of extrinsic stains on the tooth surface: An 8-week, double-blind, randomized study.

Am J Dent 2017 Jun;30(3):147-150

Department of Oral Mucosal Diseases, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.

Purpose: To assess the efficacy and safety of application of a toothpaste containing lysozyme to remove extrinsic stains on the tooth surface in an 8-week trial.

Methods: 70 adult participants with extrinsic staining of the tooth surface were recruited to this randomized, parallel-controlled, double-blind clinical trial. Participants were allocated randomly to the test group or the control group and the study procedure and correct usage of the toothpaste were explained to them. Staining, measured by the Lobene stain index, and any side effects, were recorded over the course of the 8 weeks. All data were analyzed using SAS software version 8.0.

Results: 69 participants completed the study. The value of the Lobene stain index was significantly reduced (P< 0.05) in the treatment group compared with the control group after both 4 and 8 weeks. No obvious side effects were observed.

Clinical Significance: The results of this clinical study showed that the toothpaste containing lysozyme was effective in removing extrinsic staining on the tooth surface.
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June 2017