Jianren Gu

Jianren Gu

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Adiponectin Suppresses Human Pancreatic Cancer Growth through Attenuating the β-Catenin Signaling Pathway.

Int J Biol Sci 2019 1;15(2):253-264. Epub 2019 Jan 1.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, 25/Ln. 2200 Xietu Road, Shanghai 200032, China.

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http://dx.doi.org/10.7150/ijbs.27420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367542PMC
January 2020

Mitochondrial Protein UQCRC1 is Oncogenic and a Potential Therapeutic Target for Pancreatic Cancer.

Theranostics 2020 12;10(5):2141-2157. Epub 2020 Jan 12.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.7150/thno.38704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019160PMC
January 2020

A simple AGED score for risk classification of primary liver cancer: development and validation with long-term prospective HBsAg-positive cohorts in Qidong, China.

Gut 2019 05 2;68(5):948-949. Epub 2018 May 2.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1136/gutjnl-2018-316525DOI Listing
May 2019

A novel, liver-specific long noncoding RNA LINC01093 suppresses HCC progression by interaction with IGF2BP1 to facilitate decay of GLI1 mRNA.

Cancer Lett 2019 05 18;450:98-109. Epub 2019 Feb 18.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200032, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03043835193011
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http://dx.doi.org/10.1016/j.canlet.2019.02.033DOI Listing
May 2019

Exposure to an enriched environment promotes the terminal maturation and proliferation of natural killer cells in mice.

Brain Behav Immun 2019 03 24;77:150-160. Epub 2018 Dec 24.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200032, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2018.12.017DOI Listing
March 2019

Autocrine CTHRC1 activates hepatic stellate cells and promotes liver fibrosis by activating TGF-β signaling.

EBioMedicine 2019 Feb 11;40:43-55. Epub 2019 Jan 11.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412555PMC
February 2019

The Effect of and Mechanism Underlying Autophagy in Hepatocellular Carcinoma Induced by CH12, a Monoclonal Antibody Directed Against Epidermal Growth Factor Receptor Variant III.

Cell Physiol Biochem 2018 21;46(1):226-237. Epub 2018 Mar 21.

State Key Laboratory of Oncogenes & Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1159/000488425DOI Listing
June 2018

Integrated expression profiling of potassium channels identifys KCNN4 as a prognostic biomarker of pancreatic cancer.

Biochem Biophys Res Commun 2017 12 16;494(1-2):113-119. Epub 2017 Oct 16.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200240, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2017.10.072DOI Listing
December 2017

A Fusion Receptor as a Safety Switch, Detection, and Purification Biomarker for Adoptive Transferred T Cells.

Mol Ther 2017 10 3;25(10):2270-2279. Epub 2017 Jul 3.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200032, China; CARsgen Therapeutics, Shanghai 200032, China. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2017.06.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628797PMC
October 2017

Regulator of Calcineurin 1 Gene Isoform 4, Down-regulated in Hepatocellular Carcinoma, Prevents Proliferation, Migration, and Invasive Activity of Cancer Cells and Metastasis of Orthotopic Tumors by Inhibiting Nuclear Translocation of NFAT1.

Gastroenterology 2017 09 2;153(3):799-811.e33. Epub 2017 Jun 2.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.05.045DOI Listing
September 2017

Chronic hepatitis B virus infection status is more prevalent in patients with type 2 diabetes.

J Diabetes Investig 2017 Jul 13;8(4):619-625. Epub 2017 Mar 13.

Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.

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http://dx.doi.org/10.1111/jdi.12609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497041PMC
July 2017

Enriching the Housing Environment for Mice Enhances Their NK Cell Antitumor Immunity via Sympathetic Nerve-Dependent Regulation of NKG2D and CCR5.

Cancer Res 2017 04 12;77(7):1611-1622. Epub 2017 Jan 12.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-2143DOI Listing
April 2017

Anti-angiogenesis through noninvasive to minimally invasive intraocular delivery of the peptide CC12 identified by in vivo-directed evolution.

Biomaterials 2017 01 30;112:218-233. Epub 2016 Sep 30.

Department of Ophthalmology, Shanghai Key Laboratory of Fundus Disease, Shanghai General Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 200080, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2016.09.022DOI Listing
January 2017

EGFR regulates iron homeostasis to promote cancer growth through redistribution of transferrin receptor 1.

Cancer Lett 2016 10 11;381(2):331-40. Epub 2016 Aug 11.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200032, China. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2016.08.006DOI Listing
October 2016

Complex clonal mosaicism within microdissected intestinal metaplastic glands without concurrent gastric cancer.

J Med Genet 2016 09 9;53(9):643-6. Epub 2016 Jun 9.

Bio-ID Center, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, P. R. China State Key Laboratory for Oncogenes and Related Genes, Shanghai Jiao Tong University, Shanghai, P. R. China.

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http://dx.doi.org/10.1136/jmedgenet-2016-103872DOI Listing
September 2016

Combination of an anti-EGFRvIII antibody CH12 with Rapamycin synergistically inhibits the growth of EGFRvIII+PTEN-glioblastoma in vivo.

Oncotarget 2016 Apr;7(17):24752-65

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.18632/oncotarget.8407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029739PMC
April 2016

Enriched environment housing enhances the sensitivity of mouse pancreatic cancer to chemotherapeutic agents.

Biochem Biophys Res Commun 2016 Apr 28;473(2):593-9. Epub 2016 Mar 28.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.03.128DOI Listing
April 2016

Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs.

Nat Commun 2016 Apr 6;7:11215. Epub 2016 Apr 6.

Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China.

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http://dx.doi.org/10.1038/ncomms11215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823868PMC
April 2016

Development of self-assembling peptide nanovesicle with bilayers for enhanced EGFR-targeted drug and gene delivery.

Biomaterials 2016 Mar 29;82:194-207. Epub 2015 Dec 29.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200032, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2015.12.015DOI Listing
March 2016

Synergistic antitumor efficacy against the EGFRvIII+HER2+ breast cancers by combining trastuzumab with anti-EGFRvIII antibody CH12.

Oncotarget 2015 Nov;6(36):38840-53

State Key Laboratory of Oncogenes & Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai,China.

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http://dx.doi.org/10.18632/oncotarget.6111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770741PMC
November 2015

MiR-199a-5p is negatively associated with malignancies and regulates glycolysis and lactate production by targeting hexokinase 2 in liver cancer.

Hepatology 2015 Oct 4;62(4):1132-44. Epub 2015 Jul 4.

Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1002/hep.27929DOI Listing
October 2015

Mineralocorticoid receptor suppresses cancer progression and the Warburg effect by modulating the miR-338-3p-PKLR axis in hepatocellular carcinoma.

Hepatology 2015 Oct 4;62(4):1145-59. Epub 2015 Aug 4.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

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http://dx.doi.org/10.1002/hep.27940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755033PMC
October 2015

LIFR functions as a metastasis suppressor in hepatocellular carcinoma by negatively regulating phosphoinositide 3-kinase/AKT pathway.

Carcinogenesis 2015 Oct 27;36(10):1201-12. Epub 2015 Jul 27.

Department of Pathology, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai 200438, China.

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http://dx.doi.org/10.1093/carcin/bgv108DOI Listing
October 2015

Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis.

Cell Res 2015 Aug 3;25(8):981-4. Epub 2015 Jul 3.

Department of Oncology, Shanghai Cancer Center and Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University; Shanghai 200032, China.

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http://dx.doi.org/10.1038/cr.2015.82DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528056PMC
August 2015

High level of serum protein DKK1 predicts poor prognosis for patients with hepatocellular carcinoma after hepatectomy.

Hepat Oncol 2015 Jul 1;2(3):231-244. Epub 2015 Apr 1.

State Key Laboratory of Oncogenes & Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, No.25/Ln 2200 XieTu Road, Shanghai 200032, China.

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http://dx.doi.org/10.2217/hep.15.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095183PMC
July 2015

Spatially defined microsatellite analysis reveals extensive genetic mosaicism and clonal complexity in intestinal metaplastic glands.

Int J Cancer 2015 Jun 26;136(12):2973-9. Epub 2014 Nov 26.

Bio-ID Center, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, People's Republic of China; State Key Laboratory for Oncogenes & Related Genes, Shanghai Jiao Tong University, Shanghai, People's Republic of China.

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http://dx.doi.org/10.1002/ijc.29340DOI Listing
June 2015

Leptin signaling enhances cell invasion and promotes the metastasis of human pancreatic cancer via increasing MMP-13 production.

Oncotarget 2015 Jun;6(18):16120-34

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599260PMC
http://dx.doi.org/10.18632/oncotarget.3878DOI Listing
June 2015

Hepatic stellate cells activated by acidic tumor microenvironment promote the metastasis of hepatocellular carcinoma via osteopontin.

Cancer Lett 2015 Jan 27;356(2 Pt B):713-20. Epub 2014 Oct 27.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, No. 25/Ln 2200 Xie-Tu Road, Shanghai 200032, China. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2014.10.021DOI Listing
January 2015

Enriched environment inhibits mouse pancreatic cancer growth and down-regulates the expression of mitochondria-related genes in cancer cells.

Sci Rep 2015 Jan 19;5:7856. Epub 2015 Jan 19.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, 25/Ln. 2200 Xietu Road, Shanghai 200032, China.

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http://dx.doi.org/10.1038/srep07856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297951PMC
January 2015

Genome-wide screening identified that miR-134 acts as a metastasis suppressor by targeting integrin β1 in hepatocellular carcinoma.

PLoS One 2014 3;9(2):e87665. Epub 2014 Feb 3.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087665PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912066PMC
December 2014

Novel natural mutations in the hepatitis B virus reverse transcriptase domain associated with hepatocellular carcinoma.

PLoS One 2014 1;9(5):e94864. Epub 2014 May 1.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0094864PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006920PMC
December 2014

Development of T cells redirected to glypican-3 for the treatment of hepatocellular carcinoma.

Clin Cancer Res 2014 Dec 15;20(24):6418-28. Epub 2014 Oct 15.

State Key Laboratory of Oncogenes & Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

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http://clincancerres.aacrjournals.org/content/early/2014/11/
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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-14-1170DOI Listing
December 2014

MiR-525-3p enhances the migration and invasion of liver cancer cells by downregulating ZNF395.

PLoS One 2014 5;9(3):e90867. Epub 2014 Mar 5.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0090867PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944804PMC
November 2014

DNA methylation-mediated silencing of matricellular protein dermatopontin promotes hepatocellular carcinoma metastasis by α3β1 integrin-Rho GTPase signaling.

Oncotarget 2014 Aug;5(16):6701-15

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196157PMC
http://dx.doi.org/10.18632/oncotarget.2239DOI Listing
August 2014

Quantitative implementation of the endogenous molecular-cellular network hypothesis in hepatocellular carcinoma.

Interface Focus 2014 Jun;4(3):20130064

Ministry of Education Key Laboratory of Systems Biomedicine, Shanghai Center for Systems Biomedicine , Shanghai Jiao Tong University , Shanghai 200240 , People's Republic of China ; Department of Physics , Shanghai Jiao Tong University , Shanghai 200240 , People's Republic of China ; State Key Laboratory for Oncogenes and Related Genes, Shanghai Cancer Institute , Shanghai Jiao Tong University School of Medicine , Shanghai 200032 , People's Republic of China.

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http://dx.doi.org/10.1098/rsfs.2013.0064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996582PMC
June 2014

CTHRC1 acts as a prognostic factor and promotes invasiveness of gastrointestinal stromal tumors by activating Wnt/PCP-Rho signaling.

Neoplasia 2014 Mar 13;16(3):265-78, 278.e1-13. Epub 2014 Apr 13.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2014.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094796PMC
March 2014

An EpCAM/CD3 bispecific antibody efficiently eliminates hepatocellular carcinoma cells with limited galectin-1 expression.

Cancer Immunol Immunother 2014 Feb 1;63(2):121-32. Epub 2013 Nov 1.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, No. 25/Ln2200, XieTu Rd, Shanghai, 200032, China.

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http://search.proquest.com/openview/4d1d88ecba3590e8d492f7d7
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http://link.springer.com/10.1007/s00262-013-1497-4
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http://dx.doi.org/10.1007/s00262-013-1497-4DOI Listing
February 2014

Amplification of MPZL1/PZR promotes tumor cell migration through Src-mediated phosphorylation of cortactin in hepatocellular carcinoma.

Cell Res 2014 Feb 3;24(2):204-17. Epub 2013 Dec 3.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200032, China.

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http://dx.doi.org/10.1038/cr.2013.158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915911PMC
February 2014

A novel EGFR isoform confers increased invasiveness to cancer cells.

Cancer Res 2013 Dec 15;73(23):7056-67. Epub 2013 Nov 15.

Authors' Affiliations: State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine; Neurosurgery Department of Huashan Hospital, Fudan University; Shanghai Lung Tumor Clinical Medical Center, Chest Hospital Affiliated to Shanghai Jiao Tong University; Laboratory of Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, PR China; and Department of Dermatology, Duke University Medical Center, Durham, North Carolina.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-0194DOI Listing
December 2013

Acetylcholine acts on androgen receptor to promote the migration and invasion but inhibit the apoptosis of human hepatocarcinoma.

PLoS One 2013 19;8(4):e61678. Epub 2013 Apr 19.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0061678PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631145PMC
November 2013

Identification and impact of hepatitis B virus DNA and antigens in pancreatic cancer tissues and adjacent non-cancerous tissues.

Cancer Lett 2013 Jul 7;335(2):447-54. Epub 2013 Mar 7.

Department of Molecular Diagnostics, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1016/j.canlet.2013.03.001DOI Listing
July 2013

Activation of androgen receptor induces ID1 and promotes hepatocellular carcinoma cell migration and invasion.

Mol Oncol 2012 Oct 5;6(5):507-15. Epub 2012 Jul 5.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai 200032, China.

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http://dx.doi.org/10.1016/j.molonc.2012.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528389PMC
October 2012

Serum DKK1 as a protein biomarker for the diagnosis of hepatocellular carcinoma: a large-scale, multicentre study.

Lancet Oncol 2012 Aug 26;13(8):817-26. Epub 2012 Jun 26.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1016/S1470-2045(12)70233-4DOI Listing
August 2012

Transient mTOR inhibition facilitates continuous growth of liver tumors by modulating the maintenance of CD133+ cell populations.

PLoS One 2011 1;6(12):e28405. Epub 2011 Dec 1.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Renji Hospital, Shanghai Cancer Institute, Shanghai, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0028405PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228748PMC
May 2012

Hepatitis B virus core protein variations differ in tumor and adjacent nontumor tissues from patients with hepatocellular carcinoma.

Intervirology 2012 16;55(1):29-35. Epub 2011 Feb 16.

Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1159/000322832DOI Listing
February 2012

Identification of an exon 4-deletion variant of epidermal growth factor receptor with increased metastasis-promoting capacity.

Neoplasia 2011 May;13(5):461-71

State Key Laboratory of Oncogenes and Related Genes, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Cancer Institute.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084623PMC
http://dx.doi.org/10.1593/neo.101744DOI Listing
May 2011

Growth suppression of human hepatocellular carcinoma xenografts by a monoclonal antibody CH12 directed to epidermal growth factor receptor variant III.

J Biol Chem 2011 Feb 16;286(7):5913-20. Epub 2010 Dec 16.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Medical School of Shanghai Jiaotong University, Shanghai 200032, China.

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http://dx.doi.org/10.1074/jbc.M110.192252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037704PMC
February 2011

MicroRNA-181a modulates gene expression of zinc finger family members by directly targeting their coding regions.

Nucleic Acids Res 2010 Nov 29;38(20):7211-8. Epub 2010 Jun 29.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1093/nar/gkq564DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978345PMC
November 2010

A novel gene delivery system targeting Tie2 for cancer gene therapy.

Anticancer Res 2010 Jun;30(6):1999-2004

Department of Medical Oncology, Cancer Hospital of Fudan University, Department of Oncology, Fudan University, Shanghai, China.

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June 2010

Cancer stem/progenitor cells are highly enriched in CD133+CD44+ population in hepatocellular carcinoma.

Int J Cancer 2010 May;126(9):2067-78

Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1002/ijc.24868DOI Listing
May 2010

Gain of miR-151 on chromosome 8q24.3 facilitates tumour cell migration and spreading through downregulating RhoGDIA.

Nat Cell Biol 2010 Apr 21;12(4):390-9. Epub 2010 Mar 21.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai Jiao Tong University School of Medicine, Shanghai 200032, China.

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http://dx.doi.org/10.1038/ncb2039DOI Listing
April 2010

Synthesis and characterization of stearyl protamine and investigation of their complexes with DNA for gene delivery.

Colloids Surf B Biointerfaces 2009 Oct 4;73(1):36-41. Epub 2009 May 4.

School of Pharmacy, Shanghai Jiaotong University, 800 Dongchuan Road, Shanghai 200240, People's Republic of China.

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http://linkinghub.elsevier.com/retrieve/pii/S092777650900185
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http://dx.doi.org/10.1016/j.colsurfb.2009.04.026DOI Listing
October 2009

A metabonomic study of hepatitis B-induced liver cirrhosis and hepatocellular carcinoma by using RP-LC and HILIC coupled with mass spectrometry.

Mol Biosyst 2009 Aug 17;5(8):868-76. Epub 2009 Jun 17.

CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.

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http://xlink.rsc.org/?DOI=b820224a
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http://dx.doi.org/10.1039/b820224aDOI Listing
August 2009

Meeting report: the 2009 Westlake International Conference on Personalized Medicine.

OMICS 2009 Aug;13(4):285-9

Zhejiang-California Nanosystems Institute, Zhejiang University, Hangzhou 310029, People's Republic of China.

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http://dx.doi.org/10.1089/omi.2009.0MReDOI Listing
August 2009

Small interfering RNA targeting the subunit ATP6L of proton pump V-ATPase overcomes chemoresistance of breast cancer cells.

Cancer Lett 2009 Jul 18;280(1):110-9. Epub 2009 Mar 18.

National Laboratory for Oncogenes and Related Genes, Cancer Institute, Shanghai Jiao Tong University School of Medicine, No. 25/2200 Xietu Road, Shanghai 200032, PR China.

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July 2009

Combination of alpha-1-acid glycoprotein and alpha-fetoprotein as an improved diagnostic tool for hepatocellular carcinoma.

Clin Chim Acta 2009 Jan 30;399(1-2):97-101. Epub 2008 Sep 30.

Mochtar Riady Institute for Nanotechnology, Lippo Karawaci, Banten, Indonesia.

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http://dx.doi.org/10.1016/j.cca.2008.09.024DOI Listing
January 2009

Profiling of endogenous serum phosphorylated peptides by titanium (IV) immobilized mesoporous silica particles enrichment and MALDI-TOFMS detection.

Anal Chem 2009 Jan;81(1):94-104

Key Laboratory of Separation Science for Analytical Chemistry, National Chromatographic R&A Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, China.

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http://pubs.acs.org/doi/abs/10.1021/ac801974f
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January 2009

Analysis of ABCG2 expression and side population identifies intrinsic drug efflux in the HCC cell line MHCC-97L and its modulation by Akt signaling.

Carcinogenesis 2008 Dec 26;29(12):2289-97. Epub 2008 Sep 26.

Department of General Surgery, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, PR China.

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http://carcin.oxfordjournals.org/content/29/12/2289.full.pdf
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http://dx.doi.org/10.1093/carcin/bgn223DOI Listing
December 2008

Diagnostic and prognostic implications of microRNAs in human hepatocellular carcinoma.

Int J Cancer 2008 Oct;123(7):1616-22

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai Jiao Tong University, Shanghai, China.

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http://dx.doi.org/10.1002/ijc.23693DOI Listing
October 2008

Analysis of acetylcholine, choline and butyrobetaine in human liver tissues by hydrophilic interaction liquid chromatography-tandem mass spectrometry.

J Pharm Biomed Anal 2008 Aug 29;47(4-5):870-5. Epub 2008 Feb 29.

National Chromatographic R&A Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, China.

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http://dx.doi.org/10.1016/j.jpba.2008.02.022DOI Listing
August 2008

Upregulation of miR-23a approximately 27a approximately 24 decreases transforming growth factor-beta-induced tumor-suppressive activities in human hepatocellular carcinoma cells.

Int J Cancer 2008 Aug;123(4):972-8

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Medical School of Shanghai Jiaotong University, Shanghai, China.

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http://dx.doi.org/10.1002/ijc.23580DOI Listing
August 2008

Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

Proteomics 2008 Apr;8(7):1346-61

National Chromatographic R&A Center, Dalian Institute of Chemical Physics, The Chinese Academy of Sciences, Dalian, China.

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http://dx.doi.org/10.1002/pmic.200700884DOI Listing
April 2008

Dysfunction of murine dendritic cells induced by incubation with tumor cells.

Cell Mol Immunol 2008 Apr;5(2):133-40

The National Laboratory for Oncogenes and Related Genes, Cancer Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1038/cmi.2008.16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651268PMC
April 2008

Identification and characterization of a novel peptide ligand of Tie2 for targeting gene therapy.

Acta Biochim Biophys Sin (Shanghai) 2008 Mar;40(3):217-25

Department of Medical Oncology, Cancer Hospital of Fudan University, Shanghai 200032, China.

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http://dx.doi.org/10.1111/j.1745-7270.2008.00389.xDOI Listing
March 2008

Choline transporters in human lung adenocarcinoma: expression and functional implications.

Acta Biochim Biophys Sin (Shanghai) 2007 Sep;39(9):668-74

Medical College of Fudan University, Shanghai 200032, China.

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http://dx.doi.org/10.1111/j.1745-7270.2007.00323.xDOI Listing
September 2007

Cloning, expression and characterization of human tissue-specific DNA polymerase lambda2.

Sci China C Life Sci 2007 Aug;50(4):457-65

State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai 200433, China.

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http://dx.doi.org/10.1007/s11427-007-0059-4DOI Listing
August 2007

Real-time imaging nuclear translocation of Akt1 in HCC cells.

Biochem Biophys Res Commun 2007 May 26;356(4):1038-43. Epub 2007 Mar 26.

Shanghai Medical College, Fudan University, Shanghai, and Department of General Surgery, The First Affiliated Hospital, Hangzhou, China.

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http://dx.doi.org/10.1016/j.bbrc.2007.03.092DOI Listing
May 2007

CD133 positive hepatocellular carcinoma cells possess high capacity for tumorigenicity.

Int J Cancer 2007 Apr;120(7):1444-50

Department of General Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, People's Republic of China.

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http://doi.wiley.com/10.1002/ijc.22476
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April 2007

Capillary electrophoresis analysis of poly(ethylene glycol) and ligand-modified polylysine gene delivery vectors.

Anal Biochem 2007 Apr 20;363(2):204-9. Epub 2007 Jan 20.

School of Life Science and Biotechnology, Shanghai Jiao-Tong University, Shanghai 200240, PR China.

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http://linkinghub.elsevier.com/retrieve/pii/S000326970700041
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April 2007

Molecular cloning and characterization of human Aph2 gene, involved in AP-1 regulation by interaction with JAB1.

Biochim Biophys Acta 2006 Nov-Dec;1759(11-12):514-25. Epub 2006 Oct 20.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute and Cancer Institute of Shanghai Jiaotong University, Shanghai 200032, PR China.

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http://dx.doi.org/10.1016/j.bbaexp.2006.10.002DOI Listing
March 2007

BNIPL-2 promotes the invasion and metastasis of human hepatocellular carcinoma cells.

Oncol Rep 2007 Mar;17(3):605-10

National Laboratory for Oncogenes and Related Genes, WHO Collaborating Center for Research on Cancer, Shanghai Cancer Institute, Shanghai Jiao Tong University, Shanghai 200032, P.R. China.

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March 2007

Identification of carboxypeptidase of glutamate like-B as a candidate suppressor in cell growth and metastasis in human hepatocellular carcinoma.

Clin Cancer Res 2006 Nov;12(22):6617-25

National Laboratory for Oncogenes and Related Genes, Cancer Institute of Shanghai, Jiao Tong University, Shanghai, China.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-1307DOI Listing
November 2006

Better gene expression by (-)gene than by (+)gene in phage gene delivery systems.

Biotechnol Prog 2006 May-Jun;22(3):626-30

National Laboratory for Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai Jiao Tong University, Shanghai 200032, P.R. China.

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http://dx.doi.org/10.1021/bp050392jDOI Listing
August 2006

The novel human gene MIP functions as a co-activator of hMafF.

Arch Biochem Biophys 2006 May 6;449(1-2):87-93. Epub 2006 Mar 6.

State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai 200433, China.

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http://dx.doi.org/10.1016/j.abb.2006.02.011DOI Listing
May 2006

High performance liquid chromatography-mass spectrometry for metabonomics: potential biomarkers for acute deterioration of liver function in chronic hepatitis B.

J Proteome Res 2006 Mar;5(3):554-61

National Chromatographic R & A Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 116023 Dalian, China.

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http://dx.doi.org/10.1021/pr050364wDOI Listing
March 2006

Identification and characterization of a novel peptide ligand of epidermal growth factor receptor for targeted delivery of therapeutics.

FASEB J 2005 Dec;19(14):1978-85

National Laboratory for Oncogenes and Related Genes, Shanghai Cancer Institute, Medical College of Shanghai Jiao Tong University, Shanghai, China.

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http://dx.doi.org/10.1096/fj.05-4058comDOI Listing
December 2005

Preparation of peptide-targeted phagemid particles using a protein III-modified helper phage.

Biotechniques 2005 Oct;39(4):493-7

Fudan University, Shanghai, Shanghai, China.

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http://dx.doi.org/10.2144/000112007DOI Listing
October 2005

The growth and metastasis of human hepatocellular carcinoma xenografts are inhibited by small interfering RNA targeting to the subunit ATP6L of proton pump.

Cancer Res 2005 Aug;65(15):6843-9

National Laboratory for Oncogenes and Related Genes, WHO Collaborating Center for Research on Cancer, Shanghai Cancer Institute, Shanghai, People's Republic of China.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-3822DOI Listing
August 2005

Plasma phospholipid metabolic profiling and biomarkers of type 2 diabetes mellitus based on high-performance liquid chromatography/electrospray mass spectrometry and multivariate statistical analysis.

Anal Chem 2005 Jul;77(13):4108-16

National Chromatographic R&A Center, Dalian Institute of Chemical Physics, the Chinese Academy of Sciences, Dalian 116023, China.

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http://dx.doi.org/10.1021/ac0481001DOI Listing
July 2005