Jianping Fu

Jianping Fu

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Jianping Fu

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Microengineered human amniotic ectoderm tissue array for high-content developmental phenotyping.

Biomaterials 2019 Sep 7;216:119244. Epub 2019 Jun 7.

Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, 48109, USA; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2019.119244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658735PMC
September 2019

Controlled modelling of human epiblast and amnion development using stem cells.

Nature 2019 Sep 11;573(7774):421-425. Epub 2019 Sep 11.

Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1038/s41586-019-1535-2DOI Listing
September 2019

Genome-Wide Identification of Circular RNAs Revealed the Dominant Intergenic Region Circularization Model in .

Front Genet 2019 2;10:603. Epub 2019 Jul 2.

State Key Laboratory for Quality and Safety of Agro-products, Ningbo University, Ningbo, China.

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http://dx.doi.org/10.3389/fgene.2019.00603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614181PMC
July 2019

Molecular characterization of caspase-8-like and its expression induced by microcystin-LR in grass carp (Ctenopharygodon idella).

Fish Shellfish Immunol 2019 Jun 11;89:727-735. Epub 2019 Apr 11.

College of Bioscience and Bioengineering, Jiangxi Agricultural University, Nanchang, Jiangxi Province, 330045, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.fsi.2019.04.026DOI Listing
June 2019

Intein-mediated expression and purification of common carp IFN-γ and its protective effect against spring viremia of carp virus.

Fish Shellfish Immunol 2019 May 9;88:403-406. Epub 2019 Mar 9.

College of Life Science, Jiangxi Normal University, Nanchang, Jiangxi Province, 330022, China. Electronic address:

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http://dx.doi.org/10.1016/j.fsi.2019.03.022DOI Listing
May 2019

Biophysical phenotypes and determinants of anterior vs. posterior primitive streak cells derived from human pluripotent stem cells.

Acta Biomater 2019 Mar 11;86:125-134. Epub 2019 Jan 11.

Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2019.01.017DOI Listing
March 2019

Back-focal-plane interferometric detection of nanoparticles in spatially confined microfluidic channels.

Rev Sci Instrum 2019 Feb;90(2):023107

Department of Pharmaceutical Sciences, University of Michigan, 428 Church Street, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1063/1.5074194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382495PMC
February 2019

Identification and characterization of the interferon-γ-inducible lysosomal thiol reductase gene in Chinese soft-shelled turtle, Pelodiscus sinensis.

Dev Comp Immunol 2019 01 30;90:55-59. Epub 2018 Aug 30.

College of Life Sciences, Jiangxi Normal University, 99 Ziyang Road, Nanchang, Jiangxi Province, 330022, China. Electronic address:

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http://dx.doi.org/10.1016/j.dci.2018.08.019DOI Listing
January 2019

Functional characterization of two ABC transporters in Sinonovacula constricta gills and their barrier action in response to pathogen infection.

Int J Biol Macromol 2019 Jan 12;121:443-453. Epub 2018 Oct 12.

School of Marine Sciences, Ningbo University, Ningbo 315211, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ijbiomac.2018.10.047DOI Listing
January 2019

Acoustic Actuation of Integrin-Bound Microbubbles for Mechanical Phenotyping during Differentiation and Morphogenesis of Human Embryonic Stem Cells.

Small 2018 12 14;14(50):e1803137. Epub 2018 Nov 14.

Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.

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http://dx.doi.org/10.1002/smll.201803137DOI Listing
December 2018

Magnetothermal heating facilitates the cryogenic recovery of stem cell-laden alginate-FeO nanocomposite hydrogels.

Biomater Sci 2018 Nov;6(12):3139-3151

Department of Electronic Science and Technology, University of Science and Technology of China, Hefei, Anhui 230027, China.

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http://xlink.rsc.org/?DOI=C8BM01004H
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http://dx.doi.org/10.1039/c8bm01004hDOI Listing
November 2018

A systems mechanobiology model to predict cardiac reprogramming outcomes on different biomaterials.

Biomaterials 2018 10 28;181:280-292. Epub 2018 Jul 28.

Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA; Frankel Cardiovascular Center, University of Michigan, Ann Arbor, Michigan, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01429612183052
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http://dx.doi.org/10.1016/j.biomaterials.2018.07.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119647PMC
October 2018

Acoustic Tweezing Cytometry Induces Rapid Initiation of Human Embryonic Stem Cell Differentiation.

Sci Rep 2018 08 28;8(1):12977. Epub 2018 Aug 28.

Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.

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http://dx.doi.org/10.1038/s41598-018-30939-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113316PMC
August 2018

Transcriptome-based identification of the optimal reference genes as internal controls for quantitative RT-PCR in razor clam (Sinonovacula constricta).

Genes Genomics 2018 06 3;40(6):603-613. Epub 2018 Feb 3.

School of Marine Sciences, Ningbo University, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.

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http://dx.doi.org/10.1007/s13258-018-0661-9DOI Listing
June 2018

Highly parallel single-cell force cytometry.

Nat Biomed Eng 2018 02;2(2):60-61

Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1038/s41551-018-0198-xDOI Listing
February 2018

Nanotopography regulates motor neuron differentiation of human pluripotent stem cells.

Nanoscale 2018 Feb;10(7):3556-3565

Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48105, USA.

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http://dx.doi.org/10.1039/c7nr05430kDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815510PMC
February 2018

Transmission of measles among healthcare Workers in Hospital W, Xinjiang Autonomous Region, China, 2016.

BMC Infect Dis 2018 01 12;18(1):36. Epub 2018 Jan 12.

Chinese Center for Disease Control and Prevention, No.27, Nanwei Road, Xicheng District, Beijing, 100050, China.

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http://dx.doi.org/10.1186/s12879-018-2950-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767050PMC
January 2018

Microfluidics for cryopreservation.

Biotechnol Adv 2017 Mar - Apr;35(2):323-336. Epub 2017 Jan 30.

Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Michigan Center for Integrative Research in Critical Care, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1016/j.biotechadv.2017.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236673PMC
December 2017

An apicosome initiates self-organizing morphogenesis of human pluripotent stem cells.

J Cell Biol 2017 12 11;216(12):3981-3990. Epub 2017 Oct 11.

Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI

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http://dx.doi.org/10.1083/jcb.201704085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716285PMC
December 2017

Controlled Tubular Unit Formation from Collagen Film for Modular Tissue Engineering.

ACS Biomater Sci Eng 2017 Nov 10;3(11):2860-2868. Epub 2016 Oct 10.

Department of Mechanical Engineering, University of Michigan, 2350 Hayward Street, Ann Arbor, Michigan 48109, USA.

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http://pubs.acs.org/doi/10.1021/acsbiomaterials.6b00468
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http://dx.doi.org/10.1021/acsbiomaterials.6b00468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516786PMC
November 2017

Capillary assisted deposition of carbon nanotube film for strain sensing.

Appl Phys Lett 2017 Oct 26;111(17):173105. Epub 2017 Oct 26.

Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://aip.scitation.org/doi/10.1063/1.5001754
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http://dx.doi.org/10.1063/1.5001754DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207349PMC
October 2017

Tracking the tumor invasion front using long-term fluidic tumoroid culture.

Sci Rep 2017 09 7;7(1):10784. Epub 2017 Sep 7.

Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.

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http://www.nature.com/articles/s41598-017-10874-1
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http://dx.doi.org/10.1038/s41598-017-10874-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589910PMC
September 2017

A pluripotent stem cell-based model for post-implantation human amniotic sac development.

Nat Commun 2017 08 8;8(1):208. Epub 2017 Aug 8.

Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.

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http://dx.doi.org/10.1038/s41467-017-00236-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547056PMC
August 2017

Acoustic tweezing cytometry enhances osteogenesis of human mesenchymal stem cells through cytoskeletal contractility and YAP activation.

Biomaterials 2017 Jul 22;134:22-30. Epub 2017 Apr 22.

Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2017.04.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506541PMC
July 2017

Effects of substrate stiffness and actomyosin contractility on coupling between force transmission and vinculin-paxillin recruitment at single focal adhesions.

Mol Biol Cell 2017 Jul 3;28(14):1901-1911. Epub 2017 May 3.

Woodruff School of Mechanical Engineering, Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA 30332

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http://dx.doi.org/10.1091/mbc.E17-02-0116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541841PMC
July 2017

Microfluidic-based high-throughput optical trapping of nanoparticles.

Lab Chip 2017 06;17(12):2125-2134

Department of Pharmaceutical Sciences, University of Michigan, 428 church street, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1039/c7lc00286fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533511PMC
June 2017

Centrifugal microfluidics for sorting immune cells from whole blood.

Sens Actuators B Chem 2017 Jun 23;245:1050-1061. Epub 2017 Jan 23.

Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1016/j.snb.2017.01.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619665PMC
June 2017

Notch signaling in regulating angiogenesis in a 3D biomimetic environment.

Lab Chip 2017 05;17(11):1948-1959

Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.

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http://xlink.rsc.org/?DOI=C7LC00186J
Publisher Site
http://dx.doi.org/10.1039/c7lc00186jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223016PMC
May 2017

AC Electroosmosis-Enhanced Nanoplasmofluidic Detection of Ultralow-Concentration Cytokine.

Nano Lett 2017 04 17;17(4):2374-2380. Epub 2017 Mar 17.

Department of Cell and Developmental Biology, University of Michigan Medical School , Ann Arbor, Michigan 48109, United States.

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http://dx.doi.org/10.1021/acs.nanolett.6b05313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487264PMC
April 2017

Mechanotransduction-Induced Reversible Phenotypic Switching in Prostate Cancer Cells.

Biophys J 2017 Mar;112(6):1236-1245

Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan; University of Michigan Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan; Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2017.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376107PMC
March 2017

Mechanosensitive subcellular rheostasis drives emergent single-cell mechanical homeostasis.

Nat Mater 2016 09 30;15(9):961-967. Epub 2016 May 30.

Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1038/nmat4654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996707PMC
September 2016

Accelerated Biofluid Filling in Complex Microfluidic Networks by Vacuum-Pressure Accelerated Movement (V-PAM).

Small 2016 Sep 13;12(33):4521-30. Epub 2016 Jul 13.

Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.

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http://dx.doi.org/10.1002/smll.201601231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215695PMC
September 2016

Surface micromachining of polydimethylsiloxane for microfluidics applications.

Biomicrofluidics 2016 Sep 10;10(5):054114. Epub 2016 Oct 10.

Department of Mechanical and Aerospace Engineering, New York University , Brooklyn, New York 11201, USA.

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http://dx.doi.org/10.1063/1.4964717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065565PMC
September 2016

A Miniaturized Hemoretractometer for Blood Clot Retraction Testing.

Small 2016 Aug 1;12(29):3926-34. Epub 2016 Jun 1.

Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.

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http://dx.doi.org/10.1002/smll.201600274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980575PMC
August 2016

Clot Retraction: A Miniaturized Hemoretractometer for Blood Clot Retraction Testing (Small 29/2016).

Small 2016 Aug;12(29):3925

Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.

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http://dx.doi.org/10.1002/smll.201670144DOI Listing
August 2016

Atomic force microscopy indentation and inverse analysis for non-linear viscoelastic identification of breast cancer cells.

Math Biosci 2016 07 21;277:77-88. Epub 2016 Apr 21.

William E. Boeing Department of Aeronautics and Astronautics, Seattle, WA 98195-2400, United States. Electronic address:

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http://dx.doi.org/10.1016/j.mbs.2016.03.015DOI Listing
July 2016

Multiplexed Nanoplasmonic Temporal Profiling of T-Cell Response under Immunomodulatory Agent Exposure.

ACS Sens 2016 Jul 22;1(7):941-948. Epub 2016 Jun 22.

Department of Mechanical Engineering, Department of Pediatrics and Communicable Diseases, Department of Biomedical Engineering, Department of Cell and Developmental Biology, Michigan Center for Integrative Research in Critical Care, and Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, Michigan 48109, United States; Department of Mechanical Engineering, Department of Pediatrics and Communicable Diseases, Department of Biomedical Engineering, Department of Cell and Developmental Biology, Michigan Center for Integrative Research in Critical Care, and Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, Michigan 48109, United States.

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http://dx.doi.org/10.1021/acssensors.6b00240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960639PMC
July 2016

Supersoft lithography: candy-based fabrication of soft silicone microstructures.

Lab Chip 2015 ;15(18):3760-5

Department of Chemical Engineering, McGill University, 3610 University Street, Montreal, QC H3A 2B2, Canada.

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http://dx.doi.org/10.1039/c5lc00722dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550510PMC
May 2016

Angiogenesis in Liquid Tumors: An In Vitro Assay for Leukemic-Cell-Induced Bone Marrow Angiogenesis.

Adv Healthc Mater 2016 05 29;5(9):1014-24. Epub 2016 Feb 29.

Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.

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http://dx.doi.org/10.1002/adhm.201501007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890157PMC
May 2016

Multiparametric Biomechanical and Biochemical Phenotypic Profiling of Single Cancer Cells Using an Elasticity Microcytometer.

Small 2016 05 1;12(17):2300-11. Epub 2016 Mar 1.

Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.

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http://dx.doi.org/10.1002/smll.201503620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232842PMC
May 2016

Multiplex serum cytokine immunoassay using nanoplasmonic biosensor microarrays.

ACS Nano 2015 23;9(4):4173-81. Epub 2015 Mar 23.

†Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109, United States.

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http://dx.doi.org/10.1021/acsnano.5b00396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447431PMC
February 2016

Environmental application of millimetre-scale sponge iron (s-Fe(0)) particles (III): The effect of surface silver.

J Hazard Mater 2015 Dec 9;299:618-29. Epub 2015 Jul 9.

Environmental Engineering and Science Program, Department of Biomedical, Chemical and Environmental Engineering (DBCEE), University of Cincinnati, Cincinnati, OH 45221-0012, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jhazmat.2015.07.014DOI Listing
December 2015

Desktop aligner for fabrication of multilayer microfluidic devices.

Rev Sci Instrum 2015 Jul;86(7):075008

Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1063/1.4927197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522017PMC
July 2015

On human pluripotent stem cell control: The rise of 3D bioengineering and mechanobiology.

Biomaterials 2015 Jun 21;52:26-43. Epub 2015 Feb 21.

Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01429612150010
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http://dx.doi.org/10.1016/j.biomaterials.2015.01.078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379448PMC
June 2015

Fluorescent porous carbon nanocapsules for two-photon imaging, NIR/pH dual-responsive drug carrier, and photothermal therapy.

Biomaterials 2015 Jun 12;53:117-26. Epub 2015 Mar 12.

Department of Chemistry of College of Staten Island and The Graduate Center, The City University of New York, Staten Island, NY 10314, USA. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2015.02.087DOI Listing
June 2015

Rapid, automated, parallel quantitative immunoassays using highly integrated microfluidics and AlphaLISA.

Sci Rep 2015 Jun 15;5:11339. Epub 2015 Jun 15.

1] Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA [2] Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://me.engin.umich.edu/ibbl/pdf/2015_SciRep_Yu.pdf
Web Search
http://www.nature.com/articles/srep11339
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http://dx.doi.org/10.1038/srep11339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466892PMC
June 2015

Improving survival of disassociated human embryonic stem cells by mechanical stimulation using acoustic tweezing cytometry.

Biophys J 2015 Mar;108(6):1315-1317

Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2015.01.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375556PMC
March 2015

Two-bubble acoustic tweezing cytometry for biomechanical probing and stimulation of cells.

Biophys J 2015 Jan;108(1):32-42

Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2014.11.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286600PMC
January 2015

Nanotopographical Surfaces for Stem Cell Fate Control: Engineering Mechanobiology from the Bottom.

Nano Today 2014 Dec;9(6):759-784

Integrated Biosystems and Biomechanics Laboratory, University of Michigan, Ann Arbor, MI 48109, USA ; Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA ; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1016/j.nantod.2014.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394389PMC
December 2014

Encoding through the host-guest structure: construction of multiplexed fluorescent beads.

Chem Commun (Camb) 2014 Nov;50(90):14041-4

State Key Laboratory of Oncogenes and Related Genes, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, P. R. China.

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http://dx.doi.org/10.1039/c4cc05793gDOI Listing
November 2014

Emerging microengineered tools for functional analysis and phenotyping of blood cells.

Trends Biotechnol 2014 Nov 2;32(11):586-594. Epub 2014 Oct 2.

Integrated Biosystems and Biomechanics Laboratory, University of Michigan, Ann Arbor, MI 48109, USA; Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tibtech.2014.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252757PMC
November 2014

Single-Crystalline, Nanoporous Gallium Nitride Films With Fine Tuning of Pore Size for Stem Cell Engineering.

J Nanotechnol Eng Med 2014 Nov;5(4):0410041-410049

Biomedical Engineering, Yale University , Malone 213 , 55 Prospect Street , New Haven, CT 06511 e-mail: 

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http://dx.doi.org/10.1115/1.4030615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492071PMC
November 2014

Ultrasensitive ELISA using enzyme-loaded nanospherical brushes as labels.

Anal Chem 2014 Oct 10;86(19):9367-71. Epub 2014 Sep 10.

State Key Laboratory of Oncogenes and Related Genes, School of Biomedical Engineering, Shanghai Jiao Tong University , Shanghai 200030, P. R. China.

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http://dx.doi.org/10.1021/ac502522bDOI Listing
October 2014

Harnessing mechanobiology of human pluripotent stem cells for regenerative medicine.

ACS Chem Neurosci 2014 Aug 5;5(8):621-3. Epub 2014 Jun 5.

Department of Mechanical Engineering and ‡Department of Biomedical Engineering, University of Michigan , Ann Arbor, Michigan 48109, United States.

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http://dx.doi.org/10.1021/cn5001155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140584PMC
August 2014

Continuous-flow microfluidic blood cell sorting for unprocessed whole blood using surface-micromachined microfiltration membranes.

Lab Chip 2014 Jul;14(14):2565-75

Integrated Biosystems and Biomechanics Laboratory, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1039/c4lc00350kDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106416PMC
July 2014

Hippo/YAP-mediated rigidity-dependent motor neuron differentiation of human pluripotent stem cells.

Nat Mater 2014 Jun 13;13(6):599-604. Epub 2014 Apr 13.

1] Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA [2] Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.

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June 2014

Microfluidic blood cell sorting: now and beyond.

Small 2014 May 10;10(9):1687-703. Epub 2014 Feb 10.

Integrated Biosystems and Biomechanics Laboratory, University of Michigan, Ann Arbor, Michigan, USA; Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan, USA.

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May 2014

Integrated micro/nanoengineered functional biomaterials for cell mechanics and mechanobiology: a materials perspective.

Adv Mater 2014 Mar 12;26(10):1494-533. Epub 2013 Dec 12.

Integrated Biosystems and Biomechanics Laboratory, Department of Mechanical Engineering, University of Michigan, Ann Arbor, 48109, USA.

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http://doi.wiley.com/10.1002/adma.201304431
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March 2014

Global architecture of the F-actin cytoskeleton regulates cell shape-dependent endothelial mechanotransduction.

Integr Biol (Camb) 2014 Mar 17;6(3):300-11. Epub 2014 Jan 17.

Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1039/c3ib40223aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963173PMC
March 2014

Substrates with engineered step changes in rigidity induce traction force polarity and durotaxis.

Cell Mol Bioeng 2014 Mar 9;7(1):26-34. Epub 2013 Oct 9.

Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1007/s12195-013-0307-6DOI Listing
March 2014

Uniaxial cell stretching device for live-cell imaging of mechanosensitive cellular functions.

Rev Sci Instrum 2013 Nov;84(11):114304

Integrated Biosystems and Biomechanics Laboratory, University of Michigan, Ann Arbor, Michigan 48109, USA.

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November 2013

How vinculin regulates force transmission.

Proc Natl Acad Sci U S A 2013 Jun 28;110(24):9788-93. Epub 2013 May 28.

Woodruff School of Mechanical Engineering, Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA 30332, USA.

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June 2013

Adhesion strength-based, label-free isolation of human pluripotent stem cells.

Nat Methods 2013 May 7;10(5):438-44. Epub 2013 Apr 7.

Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.

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May 2013

Emerging microfluidic tools for functional cellular immunophenotyping: a new potential paradigm for immune status characterization.

Front Oncol 2013 22;3:98. Epub 2013 Apr 22.

Integrated Biosystems and Biomechanics Laboratory, University of Michigan Ann Arbor, MI, USA ; Department of Mechanical Engineering, University of Michigan Ann Arbor, MI, USA.

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http://journal.frontiersin.org/article/10.3389/fonc.2013.000
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April 2013

Forcing stem cells to behave: a biophysical perspective of the cellular microenvironment.

Annu Rev Biophys 2012 23;41:519-42. Epub 2012 Feb 23.

Integrated Biosystems and Biomechanics Laboratory, Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.

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March 2013

Mechanobiology: a new frontier for human pluripotent stem cells.

Integr Biol (Camb) 2013 Mar;5(3):450-7

Integrated Biosystems and Biomechanics Laboratory, University of Michigan, Ann Arbor, MI 48109, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116275PMC
March 2013

Microengineered synthetic cellular microenvironment for stem cells.

Wiley Interdiscip Rev Nanomed Nanobiotechnol 2012 Jul-Aug;4(4):414-27. Epub 2012 May 25.

Department of Mechanical Engineering, Integrated Biosystems and Biomechanics Laboratory, University of Michigan, Ann Arbor, MI, USA.

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January 2013

Microfabricated nanotopological surfaces for study of adhesion-dependent cell mechanosensitivity.

Small 2013 Jan 7;9(1):81-9. Epub 2012 Aug 7.

Integrated Biosystems and Biomechanics Laboratory, Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48105, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113413PMC
January 2013

Nanoroughened surfaces for efficient capture of circulating tumor cells without using capture antibodies.

ACS Nano 2013 Jan 5;7(1):566-75. Epub 2012 Dec 5.

Integrated Biosystems and Biomechanics Laboratory, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962680PMC
January 2013

Live-cell subcellular measurement of cell stiffness using a microengineered stretchable micropost array membrane.

Integr Biol (Camb) 2012 Oct;4(10):1289-98

Integrated Biosystems and Biomechanics Laboratory, University of Michigan, Ann Arbor, MI 48109, USA.

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October 2012

Mechanics regulates fate decisions of human embryonic stem cells.

PLoS One 2012 16;7(5):e37178. Epub 2012 May 16.

Integrated Biosystems and Biomechanics Laboratory, University of Michigan, Ann Arbor, Michigan, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353896PMC
September 2012

UV-modulated substrate rigidity for multiscale study of mechanoresponsive cellular behaviors.

Langmuir 2012 Jul 12;28(29):10789-96. Epub 2012 Jul 12.

Integrated Biosystems and Biomechanics Laboratory, University of Michigan, Ann Arbor, Michigan 48109, United States.

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July 2012

Nanotopography influences adhesion, spreading, and self-renewal of human embryonic stem cells.

ACS Nano 2012 May 16;6(5):4094-103. Epub 2012 Apr 16.

Integrated Biosystems and Biomechanics Laboratory, University of Michigan, Ann Arbor, Michigan 48109, USA.

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May 2012

Elastomeric microposts integrated into microfluidics for flow-mediated endothelial mechanotransduction analysis.

Lab Chip 2012 Apr 21;12(10):1865-73. Epub 2012 Mar 21.

Integrated Biosystems and Biomechanics Laboratory, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1039/c2lc21146gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120067PMC
April 2012

A silicone-based stretchable micropost array membrane for monitoring live-cell subcellular cytoskeletal response.

Lab Chip 2012 Feb 23;12(4):731-40. Epub 2011 Dec 23.

Integrated Biosystems and Biomechanics Laboratory, University of Michigan, Ann Arbor, MI 48105, USA.

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February 2012

In silico experimentation of glioma microenvironment development and anti-tumor therapy.

PLoS Comput Biol 2012 Feb 2;8(2):e1002355. Epub 2012 Feb 2.

Department of Biomedical Engineering, Yale University, New Haven, Connecticut, USA.

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February 2012

Nanofluidic devices for rapid continuous-flow bioseparation.

Authors:
Pan Mao Jianping Fu

Methods Mol Biol 2011 ;790:127-40

Lawrence Berkeley National Laboratory, Berkeley, CA, USA.

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January 2012

Photolithographic surface micromachining of polydimethylsiloxane (PDMS).

Lab Chip 2012 Jan 17;12(2):391-5. Epub 2011 Nov 17.

Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1039/c1lc20721kDOI Listing
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January 2012

Synergistic regulation of cell function by matrix rigidity and adhesive pattern.

Biomaterials 2011 Dec 28;32(36):9584-93. Epub 2011 Sep 28.

Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120063PMC
December 2011

Cell shape and substrate rigidity both regulate cell stiffness.

Biophys J 2011 Mar;100(5):L25-7

Institute for Medicine and Engineering, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1016/j.bpj.2010.12.3744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043219PMC
March 2011

Assaying stem cell mechanobiology on microfabricated elastomeric substrates with geometrically modulated rigidity.

Nat Protoc 2011 Feb 27;6(2):187-213. Epub 2011 Jan 27.

Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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February 2011

Mechanical regulation of cell function with geometrically modulated elastomeric substrates.

Nat Methods 2010 Sep 1;7(9):733-6. Epub 2010 Aug 1.

Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1038/nmeth.1487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069358PMC
September 2010

Continuous-flow bioseparation using microfabricated anisotropic nanofluidic sieving structures.

Nat Protoc 2009 29;4(11):1681-98. Epub 2009 Oct 29.

Research Laboratories of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/nprot.2009.176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896887PMC
February 2010

Rapid quantification of disease-marker proteins using continuous-flow immunoseparation in a nanosieve fluidic device.

Anal Chem 2009 Aug;81(16):7067-74

Research Laboratory of Electronics, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846189PMC
August 2009

Decreasing effective nanofluidic filter size by modulating electrical double layers: separation enhancement in microfabricated nanofluidic filters.

Electrophoresis 2008 Dec;29(23):4646-51

Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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December 2008

A Nanofilter Array Chip for Fast Gel-Free Biomolecule Separation.

Appl Phys Lett 2005 Dec;87(26):263902

Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139.

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December 2005