Jianling Wang

ROS-Scavenging Nanomaterials to Treat Periodontitis.

Authors:

Lihua Sui Jianling Wang Zuoxiu Xiao Yuqi Yang Zhichun Yang Kelong Ai

Front Chem 2020 4;8:595530. Epub 2020 Nov 4.

Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, China.

View Article and Find Full Text PDF

November 2020

p53-R273H promotes cancer cell migration via upregulation of neuraminidase-1.

Authors:

Tao Lv Hong Lv Junjie Fei Yajun Xie Daqing Lian Jiang Hu Lizhou Tang Xiaodong Shi Jianling Wang Shibo Zhang Fengtian Li Xianjie Jiang Yong Yi

J Cancer 2020 4;11(23):6874-6882. Epub 2020 Oct 4.

Center of Growth, Metabolism and Aging, and Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China 610064.

View Article and Find Full Text PDF

October 2020

Climate change, vulnerability, and its impacts in rural Pakistan: a review.

Authors:

Shah Fahad Jianling Wang

Environ Sci Pollut Res Int 2020 Jan 5;27(2):1334-1338. Epub 2019 Dec 5.

School of Management, Xi'an Jiaotong University, Xi'an, 710049, Shaanxi, China.

View Article and Find Full Text PDF

January 2020

Cytochrome P450 2E1-deficient MRL+/+ mice are less susceptible to trichloroethene-mediated autoimmunity: Involvement of oxidative stress-responsive signaling pathways.

Authors:

Gangduo Wang Maki Wakamiya Jianling Wang G A Shakeel Ansari M Firoze Khan

Free Radic Biol Med 2019 11 22;143:324-330. Epub 2019 Aug 22.

Department of Pathology, University of Texas Medical Branch, Galveston, TX, 77555, USA. Electronic address:

View Article and Find Full Text PDF

November 2019

In situ biosynthesized gold nanoclusters inhibiting cancer development via the PI3K-AKT signaling pathway.

Authors:

Maonan Wang Zeqian Yu Huan Feng Jianling Wang Lishan Wang Yu Zhang Lihong Yin Ying Du Hui Jiang Xuemei Wang Jiahua Zhou

J Mater Chem B 2019 09;7(35):5336-5344

Department of Hepatic-Biliary-Pancreatic Center, Zhongda Hospital, Southeast University, Nanjing, China. and Department of Hepatobiliary Surgery Research Institute, Southeast University, Nanjing, China.

View Article and Find Full Text PDF

September 2019

miR-4458 regulates cell proliferation and apoptosis through targeting SOCS1 in triple-negative breast cancer.

Authors:

Xiaomeng Liu Jianling Wang Guochao Zhang

J Cell Biochem 2019 08 14;120(8):12943-12948. Epub 2019 Mar 14.

Department of Thyroid and Breast Surgery, Jining No.1 People's Hospital, Jining, Shandong, China.

View Article and Find Full Text PDF

August 2019

Contribution of poly(ADP-ribose)polymerase-1 activation and apoptosis in trichloroethene-mediated autoimmunity.

Authors:

Gangduo Wang Huaxian Ma Jianling Wang M Firoze Khan

Toxicol Appl Pharmacol 2019 01 10;362:28-34. Epub 2018 Oct 10.

Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, United States. Electronic address:

View Article and Find Full Text PDF

January 2019

Simulated microgravity reduces intracellular-free calcium concentration by inhibiting calcium channels in primary mouse osteoblasts.

J Cell Biochem 2019 03 27;120(3):4009-4020. Epub 2018 Sep 27.

Department of Orthopedics, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.

View Article and Find Full Text PDF

March 2019

[Short-term effectiveness of Kirschner wire elastic fixation in treatment of Doyle type and mallet finger].

Authors:

Hao Yan Quanchang Tan Sheng Zhou Junsheng Yang Liyi Li Jianling Wang Xiaocheng Shi Chao Xia Ying Li

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2017 11;31(11):1287-1290

Department of Orthopedics, the 454th Hospital of Chinese PLA, Nanjing Jiangsu, 210001,

View Article and Find Full Text PDF

November 2017

Occurrence, Molecular Characterization, and Assessment of Zoonotic Risk of Cryptosporidium spp., Giardia duodenalis, and Enterocytozoon bieneusi in Pigs in Henan, Central China.

Authors:

Haiyan Wang Yiqi Zhang Yayun Wu Junqiang Li Meng Qi Tingwen Li Jianling Wang Rongjun Wang Sumei Zhang Fuchun Jian Changshen Ning Longxian Zhang

J Eukaryot Microbiol 2018 11 10;65(6):893-901. Epub 2018 Jun 10.

College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450002, Henan, China.

View Article and Find Full Text PDF

November 2018

Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer.

J Med Chem 2018 04 22;61(7):2837-2864. Epub 2018 Mar 22.

Novartis Institutes for BioMedical Research, Inc. , 250 Massachusetts Avenue , Cambridge , Massachusetts 02139 , United States.

View Article and Find Full Text PDF

April 2018

miR-424-5p regulates cell proliferation, migration and invasion by targeting doublecortin-like kinase 1 in basal-like breast cancer.

Authors:

Jianling Wang Shibing Wang Jijun Zhou Qian Qian

Biomed Pharmacother 2018 Jun 22;102:147-152. Epub 2018 Mar 22.

Department of Thyroid and Breast Surgery, Jining No. 1 People's Hospital, No. 6 Jiankang Road, Jining 272011, Shandong, China. Electronic address:

View Article and Find Full Text PDF

June 2018

Exosomes derived from bone marrow stromal cells decrease the sensitivity of leukemic cells to etoposide.

Authors:

Jianling Wang Dong Li Yong Zhuang Jinqiu Fu Xue Li Qing Shi Xiuli Ju

Oncol Lett 2017 Sep 30;14(3):3082-3088. Epub 2017 Jun 30.

Shenzhen Research Institute of Shandong University, Shenzhen, Guangdong 518057, P.R. China.

View Article and Find Full Text PDF

September 2017

Autoimmune potential of perchloroethylene: Role of lipid-derived aldehydes.

Authors:

Gangduo Wang Jianling Wang G A Shakeel Ansari M Firoze Khan

Toxicol Appl Pharmacol 2017 10 14;333:76-83. Epub 2017 Aug 14.

Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA. Electronic address:

View Article and Find Full Text PDF

October 2017

Altered miRNA expression in aniline-mediated cell cycle progression in rat spleen.

Authors:

Gangduo Wang Jianling Wang M Firoze Khan

Toxicol Mech Methods 2017 Sep 6;27(7):511-517. Epub 2017 Jun 6.

a Department of Pathology , University of Texas Medical Branch , Galveston , TX , USA.

View Article and Find Full Text PDF

September 2017

Carborane Derivative Conjugated with Gold Nanoclusters for Targeted Cancer Cell Imaging.

Authors:

Jianling Wang Leifeng Chen Jing Ye Zhiyong Li Hui Jiang Hong Yan Marina Yu Stogniy Igor B Sivaev Vladimir I Bregadze Xuemei Wang

Biomacromolecules 2017 May 4;18(5):1466-1472. Epub 2017 Apr 4.

State Key Laboratory of Bioelectronics (Chien-Shiung Wu Lab), School of Biological Science and Medical Engineering, Southeast University , Nanjing, 210096, China.

View Article and Find Full Text PDF

May 2017

Discovery of an Acrylic Acid Based Tetrahydroisoquinoline as an Orally Bioavailable Selective Estrogen Receptor Degrader for ERα+ Breast Cancer.

J Med Chem 2017 04 15;60(7):2790-2818. Epub 2017 Mar 15.

Novartis Institutes for BioMedical Research , 181 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.

View Article and Find Full Text PDF

April 2017

Dl-3-n-butylphthalide can improve the cognitive function of patients with acute ischemic stroke: a prospective intervention study.

Authors:

Haiqing Yan Zhixin Yan Xiaolu Niu Jianling Wang Yongkun Gui Ping Zhang

Neurol Res 2017 Apr 1;39(4):337-343. Epub 2017 Feb 1.

a Department of Neurology , First Affiliated Hospital of Xinxiang Medical University , Weihui , China.

View Article and Find Full Text PDF

April 2017

[Study of clinical application of manipulations of filiform needles to promote by data mining technique].

Authors:

Xinxin Feng Qingqing Yang Junlei Li Zhanna Tan Boying Li Xueliang Zhu Jing Shi Yanhui Sun Jing Xu Xiaofeng Li Xuanping Zhang Xin Zhang Yuzhu Du Na Bao Qiong Wang Chunsheng Jia Jianling Wang

Zhongguo Zhen Jiu 2016 Jul;36(7):717-722

Department of Public Course Education, Hebei University of CM, Shijiazhang 050200.

View Article and Find Full Text PDF

July 2016

Common occurrence of Cryptosporidium hominis in horses and donkeys.

Authors:

Fuchun Jian Aiqin Liu Rongjun Wang Sumei Zhang Meng Qi Wei Zhao Yadong Shi Jianling Wang Jiujian Wei Longxian Zhang Lihua Xiao

Infect Genet Evol 2016 09 3;43:261-6. Epub 2016 Jun 3.

Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. Electronic address:

View Article and Find Full Text PDF

September 2016

High-performance liquid chromatography - Ultraviolet method for the determination of total specific migration of nine ultraviolet absorbers in food simulants based on 1,1,3,3-Tetramethylguanidine and organic phase anion exchange solid phase extraction to remove glyceride.

Authors:

Jianling Wang Xiaofeng Xiao Tong Chen Tingfei Liu Huaming Tao Jun He

J Chromatogr A 2016 Jun 5;1451:58-66. Epub 2016 May 5.

National Key Laboratory of Testing for Food Contact Materials, Zhejiang Academy of Science and Technology for Inspection and Quarantine Taizhou Branch, Taizhou,China.

View Article and Find Full Text PDF

June 2016

Investigation on the association between inerleukin-10 -592C/A, 819C/T and -1082A/G gene polymorphisms and development of diabetic nephrophathy.

Authors:

Qingfeng Yin Qianqian Zhai Di Wang Jie Hai Meng Cao Jianling Wang Tao Wang

Int J Clin Exp Pathol 2015 1;8(11):15216-21. Epub 2015 Nov 1.

Department of Endocrinology, The First Affiliated Hospital of Xinxiang Medical University Weihui 453100, Henan, China.

View Article and Find Full Text PDF

October 2016

Rapid and accurate tumor-target bio-imaging through specific in vivo biosynthesis of a fluorescent europium complex.

Authors:

Jing Ye Jianling Wang Qiwei Li Xiawei Dong Wei Ge Yun Chen Xuerui Jiang Hongde Liu Hui Jiang Xuemei Wang

Biomater Sci 2016 Apr 26;4(4):652-60. Epub 2016 Jan 26.

State Key Laboratory of Bioelectronics (Chien-Shiung Wu Lab) School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, P. R. China.

View Article and Find Full Text PDF

April 2016

[Simultaneous determination of total specific migration limit of seven benzene polycarbonic acids and their derivatives in food simulants by high performance liquid chromatography-ultraviolet detection].

Authors:

Jianling Wang Xiaofeng Xiao Tong Chen Tingfei Liu Jun He Hongyi Deng Juanjuan Yang

Se Pu 2015 Aug;33(8):856-63

View Article and Find Full Text PDF

August 2015

iNOS null MRL+/+ mice show attenuation of trichloroethene-mediated autoimmunity: contribution of reactive nitrogen species and lipid-derived reactive aldehydes.

Authors:

Gangduo Wang Maki Wakamiya Jianling Wang G A S Ansari M Firoze Khan

Free Radic Biol Med 2015 Dec 4;89:770-6. Epub 2015 Nov 4.

Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555. Electronic address:

View Article and Find Full Text PDF

December 2015

Studies on properties of the xylan‑binding domain and linker sequence of xylanase XynG1‑1 from Paenibacillus campinasensis G1‑1.

Authors:

Yihan Liu Lin Huang Weiguo Li Wei Guo Hongchen Zheng Jianling Wang Fuping Lu

J Ind Microbiol Biotechnol 2015 Dec;42(12):1591-9

View Article and Find Full Text PDF

December 2015

Disorder of G2-M Checkpoint Control in Aniline-Induced Cell Proliferation in Rat Spleen.

Authors:

Jianling Wang Gangduo Wang M Firoze Khan

PLoS One 2015 20;10(7):e0131457. Epub 2015 Jul 20.

Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, United States of America.

View Article and Find Full Text PDF

April 2016

The Effect of Catheter Ablation on Left Atrial Size and Function for Patients with Atrial Fibrillation: An Updated Meta-Analysis.

Authors:

Bin Xiong Dan Li Jianling Wang Laxman Gyawali Jinjin Jing Li Su

PLoS One 2015 6;10(7):e0129274. Epub 2015 Jul 6.

Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, The Chongqing Cardiac Arrhythmias Service Center, Chongqing, China.

View Article and Find Full Text PDF

March 2016

[Levels of autoantibodies against AT1-receptor in hypertensive patients with acute coronary syndromes and its role in coronary artery vasoconstriction].

Authors:

Jingping Wang Yuean Zhang Huixian Wang Xiaoxia Zeng Jinjing Yang Jin Dong Jianling Wang Yan Yang Rijun Wang Xiaojuan Zhang Xiaohong Chai Haozhou Zhang Bao Li

Zhonghua Yi Xue Za Zhi 2015 Feb;95(7):530-2

Department of Cardiology, Shanxi Cardiovascular Hospital, Taiyuan 030024, China. Email:

View Article and Find Full Text PDF

February 2015

[Cardiac protective effect of the autoantibody against β3-adrenoceptor in rats with experimental heart failure].

Authors:

Jingping Wang Xiurui Ma Yue'an Zhang Huixian Wang Jinjing Yang Jin Dong Jianling Wang Yan Yang Bao Li

Zhonghua Xin Xue Guan Bing Za Zhi 2014 May;42(5):424-7

Department of Cardiology, Shanxi Cardiovascular Hospital, Taiyuan 030024, China.

View Article and Find Full Text PDF

May 2014

Design and synthesis of lactam-thiophene carboxylic acids as potent hepatitis C virus polymerase inhibitors.

Authors:

David Barnes-Seeman Carri Boiselle Christina Capacci-Daniel Rajiv Chopra Keith Hoffmaster Christopher T Jones Mitsunori Kato Kai Lin Sue Ma Guoyu Pan Lei Shu Jianling Wang Leah Whiteman Mei Xu Rui Zheng Jiping Fu

Bioorg Med Chem Lett 2014 Aug 20;24(16):3979-85. Epub 2014 Jun 20.

Global Discovery Chemistry, Novartis Institutes for BioMedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, United States. Electronic address:

View Article and Find Full Text PDF

August 2014

A novel approach for improving the yield of Bacillus subtilis transglutaminase in heterologous strains.

Authors:

Yihan Liu Song Lin Xiqing Zhang Xiaoguang Liu Jianling Wang Fuping Lu

J Ind Microbiol Biotechnol 2014 Aug 20;41(8):1227-35. Epub 2014 Jun 20.

Key Laboratory of Industrial Fermentation Microbiology, Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, National Engineering Laboratory for Industrial Enzymes, The College of Biotechnology, Tianjin University of Science and Technology, Tianjin, People's Republic of China.

View Article and Find Full Text PDF

August 2014

Nitrosative stress and nitrated proteins in trichloroethene-mediated autoimmunity.

Authors:

Gangduo Wang Jianling Wang Xuemei Luo G A Shakeel Ansari M Firoze Khan

PLoS One 2014 3;9(6):e98660. Epub 2014 Jun 3.

Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America.

View Article and Find Full Text PDF

January 2015

High-yield phosphatidylserine production via yeast surface display of phospholipase D from Streptomyces chromofuscus on Pichia pastoris.

Authors:

Yihan Liu Tao Zhang Jing Qiao Xiaoguang Liu Jiaxin Bo Jianling Wang Fuping Lu

J Agric Food Chem 2014 Jun 29;62(23):5354-60. Epub 2014 May 29.

Key Laboratory of Industrial Fermentation Microbiology, Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, National Engineering Laboratory for Industrial Enzymes, The College of Biotechnology, Tianjin University of Science and Technology , Tianjin 300457, People's Republic of China.

View Article and Find Full Text PDF

June 2014

A highly active alpha amylase from Bacillus licheniformis: directed evolution, enzyme characterization and structural analysis.

Authors:

Yihan Liu Shuai Fan Xiaoguang Liu Zhimeng Zhang Jianling Wang Zhengxiang Wang Fuping Lu

J Microbiol Biotechnol 2014 Jul;24(7):898-904

Key Laboratory of Industrial Fermentation Microbiology, Ministry of Education, Tianjin 300457, P. R. China , Tianjin Key Laboratory of Industrial Microbiology, Tianjin 300457, P. R. China, National Engineering Laboratory for Industrial Enzymes, Tianjin 300457, P. R. China.

View Article and Find Full Text PDF

July 2014

The Role of HLA Antibodies in HLA Mismatched Allogeneic Hematopoietic Stem Cell Transplantation.

Authors:

Xian Zhang Jianling Wang Zaitong Zhou Yang Zhang Hongxing Liu Chunrong Tong Caoxing Yu Yue Lu Yanli Zhao Min Xiong Jia Rui Zhou Sunrui Juan De Yan Liu Zhijie Wei Jianping Zhang Tong Wu Dao-Pei Lu

Clin Transpl 2014 :245-50

View Article and Find Full Text PDF

September 2015

Improvement of alkali stability and thermostability of Paenibacillus campinasensis Family-11 xylanase by directed evolution and site-directed mutagenesis.

Authors:

Hongchen Zheng Yihan Liu Mingzhe Sun Yang Han Jianling Wang Junshe Sun Fuping Lu

J Ind Microbiol Biotechnol 2014 Jan 9;41(1):153-62. Epub 2013 Nov 9.

Key Laboratory of Industrial Fermentation Microbiology, Education Ministry of China, Tianjin, 300457, China.

View Article and Find Full Text PDF

January 2014

Construction of engineered Arthrobacter simplex with improved performance for cortisone acetate biotransformation.

Authors:

Huitu Zhang Yao Tian Jianling Wang Yonghai Li Haikuan Wang Shuhong Mao Xiaoguang Liu Chunxia Wang Songtao Bie Fuping Lu

Appl Microbiol Biotechnol 2013 Nov 14;97(21):9503-14. Epub 2013 Sep 14.

Key Laboratory of Industrial Fermentation Microbiology, Ministry of Education, College of Bioengineering, Tianjin University of Science & Technology, Tianjin, 300457, People's Republic of China.

View Article and Find Full Text PDF

November 2013

N-Acetylcysteine protects against trichloroethene-mediated autoimmunity by attenuating oxidative stress.

Authors:

Gangduo Wang Jianling Wang Huaxian Ma G A S Ansari M Firoze Khan

Toxicol Appl Pharmacol 2013 Nov 28;273(1):189-95. Epub 2013 Aug 28.

Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.

View Article and Find Full Text PDF

November 2013

Solvothermal synthesis of antimony sulfide dendrites for electrochemical detection of dopamine.

Authors:

Wenguang Tao Jianling Wang Dapeng Wu Jiuli Chang Feng Wang Zhiyong Gao Fang Xu Kai Jiang

Dalton Trans 2013 Aug 2;42(32):11411-7. Epub 2013 Jul 2.

School of Chemistry and Chemical Engineering, Henan Normal University, Henan Xinxiang 453007, PR China.

View Article and Find Full Text PDF

August 2013

Advances in nano-scaled biosensors for biomedical applications.

Authors:

Jianling Wang Guihua Chen Hui Jiang Zhiyong Li Xuemei Wang

Analyst 2013 Aug 10;138(16):4427-35. Epub 2013 Jun 10.

State Key Laboratory of Bioelectronics (Chien-Shiung Wu Lab), School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, PR China.

View Article and Find Full Text PDF

August 2013

Permeability diagnosis model in drug discovery: a diagnostic tool to identify the most influencing properties for gastrointestinal permeability.

Authors:

Jianling Wang Suzanne Skolnik

Curr Top Med Chem 2013 ;13(11):1308-16

Metabolism and Pharmacokinetics, Novartis Institutes for BioMedical Research, 250 Massachusetts Ave., Cambridge, MA 02139, USA.

View Article and Find Full Text PDF

January 2014

[Rapid analysis of 28 primary aromatic amines in aqueous food simulants by high performance liquid chromatography-tandem mass spectrometry].

Authors:

Xiaofeng Xiao Jianling Wang Juanjuan Yang Tingfei Liu Tong Chen Jun He Hongyi Deng Qiyan Gao

Se Pu 2013 Jan;31(1):38-45

Taizhou Entry-Exit Inspection and Quarantine Bureau, Taizhou 318000, China.

View Article and Find Full Text PDF

January 2013

Mononuclear leukocyte infiltrate in extraplacental membranes and preterm delivery.

Authors:

Claudia Holzman Patricia K Senagore Jianling Wang

Am J Epidemiol 2013 May 20;177(10):1053-64. Epub 2013 Feb 20.

Department of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, West Fee Hall, 909 Fee Road, Room B601, East Lansing, MI 48824, USA.

View Article and Find Full Text PDF

May 2013

In vivo self-bio-imaging of tumors through in situ biosynthesized fluorescent gold nanoclusters.

Authors:

Jianling Wang Gen Zhang Qiwei Li Hui Jiang Chongyang Liu Christian Amatore Xuemei Wang

Sci Rep 2013 29;3:1157. Epub 2013 Jan 29.

State Key Laboratory of Bioelectronics-Chien-Shiung Wu Lab, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.

View Article and Find Full Text PDF

July 2013

Induction of base excision repair enzymes NTH1 and APE1 in rat spleen following aniline exposure.

Authors:

Huaxian Ma Jianling Wang Sherif Z Abdel-Rahman Paul J Boor M Firoze Khan

Toxicol Appl Pharmacol 2013 Mar 23;267(3):276-83. Epub 2013 Jan 23.

Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.

View Article and Find Full Text PDF

March 2013

Discovery and mechanism study of SIRT1 activators that promote the deacetylation of fluorophore-labeled substrate.

Authors:

Jiahui Wu Dengyou Zhang Lei Chen Jianneng Li Jianling Wang Chengqing Ning Niefang Yu Fei Zhao Dongying Chen Xiaoyan Chen Kaixian Chen Hualiang Jiang Hong Liu Dongxiang Liu

J Med Chem 2013 Feb 28;56(3):761-80. Epub 2013 Jan 28.

Department of Pharmacology III, Shanghai Institute of Materia Medica , Chinese Academy of Sciences, 555 Zu-Chong-Zhi Road, Shanghai 201203, China.

View Article and Find Full Text PDF

February 2013

Layer-by-layer assembly of graphene, Au and poly(toluidine blue O) films sensor for evaluation of oxidative stress of tumor cells elicited by hydrogen peroxide.

Authors:

Hucheng Chang Xuemei Wang Kowk-Keung Shiu Yanliang Zhu Jianling Wang Qiwei Li Baoan Chen Hui Jiang

Biosens Bioelectron 2013 Mar 9;41:789-94. Epub 2012 Oct 9.

State Key Laboratory of Bioelectronics (Chien-Shiung Wu Laboratory), Southeast University, Nanjing 210096, People's Republic of China.

View Article and Find Full Text PDF

March 2013

Overexpression of a Paenibacillus campinasensis xylanase in Bacillus megaterium and its applications to biobleaching of cotton stalk pulp and saccharification of recycled paper sludge.

Authors:

Hongchen Zheng Yihan Liu Xiaoguang Liu Yang Han Jianling Wang Fuping Lu

Bioresour Technol 2012 Dec 5;125:182-7. Epub 2012 Sep 5.

Key Laboratory of Industrial Fermentation Microbiology, Education Ministry of China, Tianjin 300457, China.

View Article and Find Full Text PDF

December 2012

Photoelectrocatalytic oxidation of glutathione based on porous TiO2-Pt nanowhiskers.

Authors:

Guihua Chen Jianling Wang Changyu Wu Chen-zhong Li Hui Jiang Xuemei Wang

Langmuir 2012 Aug 9;28(33):12393-9. Epub 2012 Aug 9.

State Key Laboratory of Bioelectronics, Southeast University, Nanjing, China.

View Article and Find Full Text PDF

August 2012

Probe ADME and test hypotheses: a PATH beyond clearance in vitro-in vivo correlations in early drug discovery.

Authors:

Leslie C Bell Jianling Wang

Expert Opin Drug Metab Toxicol 2012 Sep 11;8(9):1131-55. Epub 2012 Jun 11.

Novartis Institutes for Biomedical Research, Metabolism and Pharmacokinetics, Cambridge, MA 02139, USA.

View Article and Find Full Text PDF

September 2012

Isolation, purification, and characterization of a thermostable xylanase from a novel strain, Paenibacillus campinasensis G1-1.

Authors:

Hongchen Zheng Yihan Liu Xiaoguang Liu Jianling Wang Ying Han Fuping Lu

J Microbiol Biotechnol 2012 Jul;22(7):930-8

Key Laboratory of Industrial Fermentation Microbiology, Education Ministry of China, 300457 Tianjin, China.

View Article and Find Full Text PDF

July 2012

Imidazolopiperazines: lead optimization of the second-generation antimalarial agents.

J Med Chem 2012 May 23;55(9):4244-73. Epub 2012 Apr 23.

Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, USA.

View Article and Find Full Text PDF

May 2012

Assessment of biliary clearance in early drug discovery using sandwich-cultured hepatocyte model.

Authors:

Guoyu Pan Carri Boiselle Jianling Wang

J Pharm Sci 2012 May 9;101(5):1898-908. Epub 2012 Feb 9.

Center for Drug Safety Evaluation and Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.

View Article and Find Full Text PDF

May 2012

Protein adducts of malondialdehyde and 4-hydroxynonenal contribute to trichloroethene-mediated autoimmunity via activating Th17 cells: dose- and time-response studies in female MRL+/+ mice.

Authors:

Gangduo Wang Jianling Wang Xiuzhen Fan G A S Ansari M Firoze Khan

Toxicology 2012 Feb 9;292(2-3):113-22. Epub 2011 Dec 9.

Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555-0609, USA.

View Article and Find Full Text PDF

February 2012

Mid-pregnancy levels of angiogenic markers as indicators of pathways to preterm delivery.

Authors:

Renée S Mijal Claudia B Holzman Sarosh Rana S Ananth Karumanchi Jianling Wang Alla Sikorskii

J Matern Fetal Neonatal Med 2012 Jul 24;25(7):1135-41. Epub 2011 Oct 24.

Department of Epidemiology, Michigan State University, East Lansing, MI 48824, USA.

View Article and Find Full Text PDF

July 2012

Efficient expression of an alkaline pectate lyase gene from Bacillus subtilis and the characterization of the recombinant protein.

Authors:

Yihan Liu Guanqun Chen Jianling Wang Yujie Hao Ming Li Yu Li Bo Hu Fuping Lu

Biotechnol Lett 2012 Jan 14;34(1):109-15. Epub 2011 Sep 14.

Key Laboratory of Industrial Fermentation Microbiology, Ministry of Education, Tianjin, 300457, People's Republic of China.

View Article and Find Full Text PDF

January 2012

Predicting phospholipidosis: a fluorescence noncell based in vitro assay for the determination of drug-phospholipid complex formation in early drug discovery.

Authors:

Liping Zhou Gina Geraci Sloan Hess Linhong Yang Jianling Wang Upendra Argikar

Anal Chem 2011 Sep 19;83(18):6980-7. Epub 2011 Aug 19.

Chemical and Pharmaceutical Profiling, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States.

View Article and Find Full Text PDF

September 2011

Aniline-induced nitrosative stress in rat spleen: proteomic identification of nitrated proteins.

Authors:

Xiuzhen Fan Jianling Wang Kizhake V Soman G A S Ansari M Firoze Khan

Toxicol Appl Pharmacol 2011 Aug 15;255(1):103-12. Epub 2011 Jun 15.

Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.

View Article and Find Full Text PDF

August 2011

Imidazolopiperazines: hit to lead optimization of new antimalarial agents.

J Med Chem 2011 Jul 23;54(14):5116-30. Epub 2011 Jun 23.

Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, USA.

View Article and Find Full Text PDF

July 2011

Maximizing the outcome of early ADMET models: strategies to win the drug-hunting battles?

Authors:

Jianling Wang Alan Collis

Expert Opin Drug Metab Toxicol 2011 Apr 19;7(4):381-6. Epub 2011 Mar 19.

View Article and Find Full Text PDF

April 2011

Induction of NEIL1 and NEIL2 DNA glycosylases in aniline-induced splenic toxicity.

Authors:

Huaxian Ma Jianling Wang Sherif Z Abdel-Rahman Tapas K Hazra Paul J Boor M Firoze Khan

Toxicol Appl Pharmacol 2011 Feb 9;251(1):1-7. Epub 2010 Dec 9.

Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.

View Article and Find Full Text PDF

February 2011

Midpregnancy levels of angiogenic markers in relation to maternal characteristics.

Authors:

Renée S Mijal Claudia B Holzman Sarosh Rana S Ananth Karumanchi Jianling Wang Alla Sikorskii

Am J Obstet Gynecol 2011 Mar 10;204(3):244.e1-12. Epub 2010 Dec 10.

Department of Epidemiology, Michigan State University, East Lansing, MI, USA.

View Article and Find Full Text PDF

March 2011

Late-preterm birth and its association with cognitive and socioemotional outcomes at 6 years of age.

Authors:

Nicole M Talge Claudia Holzman Jianling Wang Victoria Lucia Joseph Gardiner Naomi Breslau

Pediatrics 2010 Dec 22;126(6):1124-31. Epub 2010 Nov 22.

Department of Epidemiology, Michigan State University, B601 West Fee Hall, East Lansing, MI 48824, USA.

View Article and Find Full Text PDF

December 2010

Enhanced expression of cyclins and cyclin-dependent kinases in aniline-induced cell proliferation in rat spleen.

Authors:

Jianling Wang Gangduo Wang Huaxian Ma M Firoze Khan

Toxicol Appl Pharmacol 2011 Jan 8;250(2):213-20. Epub 2010 Nov 8.

Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.

View Article and Find Full Text PDF

January 2011

Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.

Authors:

Xuena Lin Suzanne Skolnik Xiaohui Chen Jianling Wang

Drug Metab Dispos 2011 Feb 4;39(2):265-74. Epub 2010 Nov 4.

Metabolism and Pharmacokinetics, Novartis Institutes for BioMedical Research, Cambridge, MA 02139, USA.

View Article and Find Full Text PDF

February 2011

[Construction of eukaryotic expression vector of EGFRi-IL-24 recombinant gene].

Authors:

Jianling Wang Xinying Fan Leyuan Bao Lianxiang Du

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 2010 Apr;27(2):395-9

Tianjin Key Lab of Industrial Microbiology, College of Biotechnology, Tianjin University of Science and Technology, Tianjin 300457, China.

View Article and Find Full Text PDF

April 2010

Towards prediction of in vivo intestinal absorption using a 96-well Caco-2 assay.

Authors:

Suzanne Skolnik Xuena Lin Jianling Wang Xiao-Hui Chen Timothy He Bailin Zhang

J Pharm Sci 2010 Jul;99(7):3246-65

Metabolism and Pharmacokinetics Platform, Novartis Institutes for BioMedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.

View Article and Find Full Text PDF

July 2010

Mitigating permeability-mediated risks in drug discovery.

Authors:

Jianling Wang Suzanne Skolnik

Expert Opin Drug Metab Toxicol 2010 Feb;6(2):171-87

Novartis Institutes for Biomedical Research, Metabolism and Pharmacokinetics, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.

View Article and Find Full Text PDF

February 2010

(3,4-Dimeth-oxy-phen-yl)(4-fluoro-phen-yl)methanone.

Authors:

Quanjian Lv Jianling Wang

Acta Crystallogr Sect E Struct Rep Online 2010 Jun 5;66(Pt 7):o1585. Epub 2010 Jun 5.

Department of Quality Detection and Management, Zhengzhou College of Animal Husbandry Engineering, Zhengzhou 450011, People's Republic of China.

View Article and Find Full Text PDF

June 2010

Up-regulation of heme oxygenase-1 in rat spleen after aniline exposure.

Authors:

Jianling Wang Huaxian Ma Paul J Boor V M Sadagopa Ramanujam G A S Ansari M Firoze Khan

Free Radic Biol Med 2010 Feb 4;48(4):513-8. Epub 2009 Dec 4.

Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555-0438, USA.

View Article and Find Full Text PDF

February 2010

Recent advances in physicochemical and ADMET profiling in drug discovery.

Authors:

Jianling Wang Suzanne Skolnik

Chem Biodivers 2009 Nov;6(11):1887-99

ADME Profiling Cambridge, Metabolism and Pharmacokinetics, Novartis Institute for Biomedical Research, 250 Mass Ave, Cambridge, MA 02139, USA.

View Article and Find Full Text PDF

November 2009

High-level expression, purification and characterization of a recombinant medium-temperature alpha-amylase from Bacillus subtilis.

Authors:

Yihan Liu Fuping Lu Guanqun Chen Crystal L Snyder Jing Sun Yu Li Jianling Wang Jing Xiao

Biotechnol Lett 2010 Jan 1;32(1):119-24. Epub 2009 Sep 1.

Key Laboratory of Industrial Microbiology, Ministry of Education, Tianjin, 300457, People's Republic of China.

View Article and Find Full Text PDF

January 2010

[Effect of Panax notoginseng saponins on vascular intima hyperplasia and PCNA expression in rat aorta after balloon angioplasty].

Authors:

Jianling Wang Lu Wu Wei Zhang Changqing Deng

Zhongguo Zhong Yao Za Zhi 2009 Mar;34(6):735-9

School of Integrated Traditional Chinese and Western Medicine, Hunan University of Traditional Chinese Medicine, Changsha 410208, China.

View Article and Find Full Text PDF

March 2009

Comprehensive assessment of ADMET risks in drug discovery.

Authors:

Jianling Wang

Curr Pharm Des 2009 ;15(19):2195-219

ADME Profiling Cambridge, Metabolism and Pharmacokinetics, Novartis Institute for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.

View Article and Find Full Text PDF

September 2009

Increased nitration and carbonylation of proteins in MRL+/+ mice exposed to trichloroethene: potential role of protein oxidation in autoimmunity.

Authors:

Gangduo Wang Jianling Wang Huaxian Ma M Firoze Khan

Toxicol Appl Pharmacol 2009 Jun 28;237(2):188-95. Epub 2009 Mar 28.

Department of Pathology, University of Texas Medical Branch, 2.319 Mary Moody Northen, Galveston, TX 77555-0438, USA.

View Article and Find Full Text PDF

June 2009

Oxidative DNA damage and its repair in rat spleen following subchronic exposure to aniline.

Authors:

Huaxian Ma Jianling Wang Sherif Z Abdel-Rahman Paul J Boor M Firoze Khan

Toxicol Appl Pharmacol 2008 Dec 22;233(2):247-53. Epub 2008 Aug 22.

Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555-0438, USA.

View Article and Find Full Text PDF

December 2008

Evaluation of fluorescence- and mass spectrometry-based CYP inhibition assays for use in drug discovery.

Authors:

Leslie Bell Shari Bickford Phong Hung Nguyen Jianling Wang Timothy He Bailin Zhang Yannick Friche Alfred Zimmerlin Laszlo Urban Dejan Bojanic

J Biomol Screen 2008 Jun 12;13(5):343-53. Epub 2008 May 12.

ADME Profiling Cambridge, Metabolism and Pharmacokinetics, Global Discovery Chemistry, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts 02139, USA.

View Article and Find Full Text PDF

June 2008