Jia-Ren Lin

Jia-Ren Lin

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Jia-Ren Lin

Jia-Ren Lin

Publications by authors named "Jia-Ren Lin"

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24Publications

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Qualifying antibodies for image-based immune profiling and multiplexed tissue imaging.

Nat Protoc 2019 Oct 18;14(10):2900-2930. Epub 2019 Sep 18.

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41596-019-0206-yDOI Listing
October 2019

Determinants of drug-target interactions at the single cell level.

PLoS Comput Biol 2018 12 20;14(12):e1006601. Epub 2018 Dec 20.

Laboratory for Systems Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1006601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319770PMC
December 2018

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations.

Authors:
Alexandra B Keenan Sherry L Jenkins Kathleen M Jagodnik Simon Koplev Edward He Denis Torre Zichen Wang Anders B Dohlman Moshe C Silverstein Alexander Lachmann Maxim V Kuleshov Avi Ma'ayan Vasileios Stathias Raymond Terryn Daniel Cooper Michele Forlin Amar Koleti Dusica Vidovic Caty Chung Stephan C Schürer Jouzas Vasiliauskas Marcin Pilarczyk Behrouz Shamsaei Mehdi Fazel Yan Ren Wen Niu Nicholas A Clark Shana White Naim Mahi Lixia Zhang Michal Kouril John F Reichard Siva Sivaganesan Mario Medvedovic Jaroslaw Meller Rick J Koch Marc R Birtwistle Ravi Iyengar Eric A Sobie Evren U Azeloglu Julia Kaye Jeannette Osterloh Kelly Haston Jaslin Kalra Steve Finkbiener Jonathan Li Pamela Milani Miriam Adam Renan Escalante-Chong Karen Sachs Alex Lenail Divya Ramamoorthy Ernest Fraenkel Gavin Daigle Uzma Hussain Alyssa Coye Jeffrey Rothstein Dhruv Sareen Loren Ornelas Maria Banuelos Berhan Mandefro Ritchie Ho Clive N Svendsen Ryan G Lim Jennifer Stocksdale Malcolm S Casale Terri G Thompson Jie Wu Leslie M Thompson Victoria Dardov Vidya Venkatraman Andrea Matlock Jennifer E Van Eyk Jacob D Jaffe Malvina Papanastasiou Aravind Subramanian Todd R Golub Sean D Erickson Mohammad Fallahi-Sichani Marc Hafner Nathanael S Gray Jia-Ren Lin Caitlin E Mills Jeremy L Muhlich Mario Niepel Caroline E Shamu Elizabeth H Williams David Wrobel Peter K Sorger Laura M Heiser Joe W Gray James E Korkola Gordon B Mills Mark LaBarge Heidi S Feiler Mark A Dane Elmar Bucher Michel Nederlof Damir Sudar Sean Gross David F Kilburn Rebecca Smith Kaylyn Devlin Ron Margolis Leslie Derr Albert Lee Ajay Pillai

Cell Syst 2018 01 29;6(1):13-24. Epub 2017 Nov 29.

NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.cels.2017.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799026PMC
January 2018

Multiplexed Single-Cell Imaging: Past, Present, and Future.

Authors:
Jia-Ren Lin

Assay Drug Dev Technol 2017 Jan 22;15(1):8-10. Epub 2016 Dec 22.

Laboratory of Systems Pharmacology, HMS LINCS Center , Harvard Medical School Boston, Boston, Massachusetts.

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http://dx.doi.org/10.1089/adt.2016.765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248548PMC
January 2017

Cyclic Immunofluorescence (CycIF), A Highly Multiplexed Method for Single-cell Imaging.

Curr Protoc Chem Biol 2016 Dec 7;8(4):251-264. Epub 2016 Dec 7.

HMS LINCS Center, Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/cpch.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233430PMC
December 2016

Highly multiplexed imaging of single cells using a high-throughput cyclic immunofluorescence method.

Nat Commun 2015 Sep 24;6:8390. Epub 2015 Sep 24.

HMS LINCS Center &Laboratory of Systems Pharmacology, Harvard Medical School, Boston, Massachusetts 02115 USA.

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http://dx.doi.org/10.1038/ncomms9390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587398PMC
September 2015

DNA damage-specific deubiquitination regulates Rad18 functions to suppress mutagenesis.

J Cell Biol 2014 Jul 14;206(2):183-97. Epub 2014 Jul 14.

Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305

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http://dx.doi.org/10.1083/jcb.201311063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107794PMC
July 2014

Dosage of Dyrk1a shifts cells within a p21-cyclin D1 signaling map to control the decision to enter the cell cycle.

Mol Cell 2013 Oct;52(1):87-100

Department of Chemical and Systems Biology, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/j.molcel.2013.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039290PMC
October 2013

A two-dimensional ERK-AKT signaling code for an NGF-triggered cell-fate decision.

Mol Cell 2012 Jan 28;45(2):196-209. Epub 2011 Dec 28.

Department of Chemical and Systems Biology, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/j.molcel.2011.11.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897208PMC
January 2012

SHPRH and HLTF act in a damage-specific manner to coordinate different forms of postreplication repair and prevent mutagenesis.

Mol Cell 2011 Apr 10;42(2):237-49. Epub 2011 Mar 10.

Department of Chemical and Systems Biology, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/j.molcel.2011.02.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080461PMC
April 2011

eIF3k regulates apoptosis in epithelial cells by releasing caspase 3 from keratin-containing inclusions.

J Cell Sci 2008 Jul 24;121(Pt 14):2382-93. Epub 2008 Jun 24.

Institute of Biochemical Sciences, National Taiwan University, Taiwan.

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http://dx.doi.org/10.1242/jcs.021394DOI Listing
July 2008

An application of bioinformatics and text mining to the discovery of novel genes related to bone biology.

Bone 2007 May 20;40(5):1378-88. Epub 2007 Jan 20.

Department of Orthopaedic Surgery, UC Davis Medical Center, Orthopaedic Research Laboratory, 4635 2nd Avenue, Room 2000, Sacramento, CA 95817, USA.

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http://dx.doi.org/10.1016/j.bone.2006.12.067DOI Listing
May 2007

[Inhibitory effect of potential metastasis in SGC-7901 cells induced by beta-ionone].

Wei Sheng Yan Jiu 2005 Jul;34(4):435-8

School of Public Health, Harbin Medical University, Harbin 150086, China.

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July 2005

Bidirectional signals transduced by DAPK-ERK interaction promote the apoptotic effect of DAPK.

EMBO J 2005 Jan 16;24(2):294-304. Epub 2004 Dec 16.

Institute of Molecular Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1038/sj.emboj.7600510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC545805PMC
January 2005

Uncoordinated regulation of stress fibers and focal adhesions by DAP kinase.

J Cell Sci 2003 Dec;116(Pt 23):4777-90

Institute of Molecular Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1242/jcs.00794DOI Listing
December 2003