Publications

Benign extracerebral fluid collection complicated by subdural hematoma and fluid collection: clinical characteristics and management.
Childs Nerv Syst 2018 Feb 9;34(2):235-245. Epub 2017 Sep 9.
Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.

Genomic analysis of synchronous intracranial meningiomas with different histological grades.
J Neurooncol 2018 Feb 8. Epub 2018 Feb 8.
Department of Neurosurgery, Seoul National University College of Medicine, Seoul National University Hospital, 103 Daehak-ro (Yeongeon-dong), Jongno-gu, Seoul, South Korea.

Surgical outcome and predictive factors of epilepsy surgery in pediatric isolated focal cortical dysplasia.
Epilepsy Res 2018 Jan 27;139:54-59. Epub 2017 Nov 27.
Department of Pediatrics, Pediatric Clinical Neuroscience Center, Seoul National University Children's Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:

Extensive brain infarction involving deep structures during an acetazolamide-challenged single-photon emission computed tomography scan in a patient with moyamoya disease.
Childs Nerv Syst 2017 Nov 8;33(11):2029-2033. Epub 2017 Jul 8.
Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.

Repositioning disulfiram as a radiosensitizer against atypical teratoid/rhabdoid tumor.
Neuro Oncol 2017 Aug;19(8):1079-1087
Division of Pediatric Neurosurgery, Pediatric Clinical Neuroscience Center, Seoul National University Children's Hospital, Seoul National University College of Medicine, Seoul, South Korea; Adolescent Cancer Center, Seoul National University Cancer Hospital, Seoul, South Korea; Department of Radiation Oncology, Seoul National University Hospital, Seoul, South Korea; Department of Anatomy, Seoul National University College of Medicine, Seoul, South Korea; Department of Pathology, Seoul National University College of Medicine, Seoul, South Korea; Department of Pediatrics, Seoul National University Children's Hospital, Seoul, South Korea; Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, South Korea; Department of Health Science and Technology, Samsung Advanced Institute for Health Sciences and Technology, SungKyunKwan University, Seoul, South Korea; Department of Anatomy and Cell Biology, SungKyunKwan University School of Medicine, Suwon, South Korea; Single Cell Network Research Center, Sungkyunkwan University School of Medicine, Suwon, South Korea.


Intertumoral Heterogeneity within Medulloblastoma Subgroups.
Cancer Cell 2017 Jun;31(6):737-754.e6
The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A1, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada. Electronic address:

Syringomyelia caused by an arachnoid web in a patient with shunted Dandy-Walker malformation.
Childs Nerv Syst 2017 Apr 7;33(4):665-670. Epub 2016 Nov 7.
Division of Pediatric Neurosurgery, Department of Neurosurgery, Seoul National University Children's Hospital and Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 110-744, Republic of Korea.

A subpopulation of cancer stem cells identifies radiographic characteristics in glioblastoma.
Oncol Lett 2017 Mar 28;13(3):1175-1182. Epub 2016 Dec 28.
Department of Neurosurgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul 110-744, Republic of Korea.

Comparative analysis of bleeding risk by the location and shape of arachnoid cysts: a finite element model analysis.
Childs Nerv Syst 2017 Jan 7;33(1):125-134. Epub 2016 Oct 7.
Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.

A method of posterior fossa dural incision to minimize hemorrhage from the occipital sinus: the "mosquito" method.
Childs Nerv Syst 2016 Dec 21;32(12):2429-2431. Epub 2016 Jul 21.
Division of Pediatric Neurosurgery, Department of Neurosurgery, Seoul National University Children's Hospital & Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 110-744, Republic of Korea.

Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.
J Clin Oncol 2016 Jul 6;34(21):2468-77. Epub 2016 Jun 6.
Vijay Ramaswamy, Stephen C. Mack, Alvaro Lassaletta, Betty Luu, Florence M.G. Cavalli, Uri Tabori, Ute Bartels, Eric Bouffet, Cynthia E. Hawkins, James T. Rutka, Peter Dirks, and Michael D. Taylor, The Hospital for Sick Children; Vijay Ramaswamy, Kenneth Aldape, James T. Rutka, and Michael D. Taylor, University of Toronto; Kenneth Aldape, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario; Christopher Dunham and Juliette Hukin, British Columbia Children's Hospital; Juliette Hukin, University of British Columbia, Vancouver, British Columbia; David D. Eisenstat, Dorcas Fulton, and Frank K.H. van Landeghem, University of Alberta, Edmonton; Jennifer A. Chan, University of Calgary, Calgary, Alberta; Nada Jabado and Kevin Petrecca, McGill University, Montreal, Quebec, Canada; Thomas Hielscher, Kristian W. Pajtler, David T.W. Jones, Marcel Kool, Stefan M. Pfister, and Andrey Korshunov, German Cancer Research Center; Stefan M. Pfister, University Hospital Heidelberg, Heidelberg; Marc Remke, University Hospital Düsseldorf, Düsseldorf; Martin Mynarek, Stefan Rutkowski, and Katja von Hoff, University Medical Center Hamburg-Eppendorf, Hamburg; Ulrich Schüller, Ludwig-Maximilians-Universität, Munich, Germany; Stephen C. Mack, Cleveland Clinic Foundation, Cleveland; Maryam Fouladi, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Tong Lin, Amar Gajjar, Thomas E. Merchant, and David W. Ellison, St Jude Children's Research Hospital, Memphis; Lola B. Chambless, Vanderbilt Medical Center, Nashville, TN; Sridharan Gururangan, Roger E. McLendon, and Eric S. Lipp, Duke University, Durham; Jing Wu, University of North Carolina at Chapel Hill, Chapel Hill, NC; Mariarita Santi, Children's Hospital of Philadelphia; Lyndsey Emery, Hospital of the University of Pennsylvania, Philadelphia; Ronald L. Hamilton and Ian F. Pollack, University of Pittsburgh School of Medicine; Frank Lieberman, University of Pittsburgh Medical Cen

Association between moyamoya syndrome and the RNF213 c.14576G>A variant in patients with neurofibromatosis Type 1.
J Neurosurg Pediatr 2016 Jun 5;17(6):717-22. Epub 2016 Feb 5.
Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul National University College of Medicine;

Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis.
Lancet Oncol 2016 Apr 12;17(4):484-495. Epub 2016 Mar 12.
Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada. Electronic address:

Divergent clonal selection dominates medulloblastoma at recurrence.
Nature 2016 Jan 13;529(7586):351-7. Epub 2016 Jan 13.
Developmental &Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.

Comparison of clinical and radiological manifestations and surgical outcomes of pediatric Chiari I malformations in different age groups.
Childs Nerv Syst 2015 Nov 1;31(11):2091-101. Epub 2015 Aug 1.
Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.

Deregulation of Retinaldehyde Dehydrogenase 2 Leads to Defective Angiogenic Function of Endothelial Colony-Forming Cells in Pediatric Moyamoya Disease.
Arterioscler Thromb Vasc Biol 2015 Jul 28;35(7):1670-7. Epub 2015 May 28.
From the Department of Anatomy (J.Y.L.), Division of Pediatric Neurosurgery, Seoul National University Children's Hospital (J.Y.L., Y.J.M., S.-A.C., K.-C.W., J.W.H., J.H.P., S.-K.K.), and Department of Neurosurgery (H.S.K., J.E.K.), Seoul National University College of Medicine, Seoul, Korea; Samsung Genome Institute, Samsung Medical Center, Seoul, Korea (H.-O.L., J.-G.J., W.-Y.P.); College of Pharmacy, Sunchon National University, Jeonnam, Korea (A.-K.P.); and Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon, Korea (H.-O.L., W.-Y.P.).

Disulfiram modulates stemness and metabolism of brain tumor initiating cells in atypical teratoid/rhabdoid tumors.
Neuro Oncol 2015 Jun 4;17(6):810-21. Epub 2014 Nov 4.
Division of Pediatric Neurosurgery, Pediatric Clinical Neuroscience Center, Seoul National University Children's Hospital, Seoul, Republic of Korea (S.A.C., J.W.C., K.-C.W., J.H.P., J.Y.L., D.E., S.-K.K.); Adolescent Cancer Center, Seoul National University Cancer Hospital, Seoul, Republic of Korea (S.A.C., J.W.C., J.H.P., J.Y.L., K.D.P., D.E., S.-K.K.); Department of Pediatrics, Seoul National University Children's Hospital, Seoul, Republic of Korea (K.D.P.); Department of Pathology, Seoul National University Children's Hospital, Seoul, Republic of Korea (S-H.P.); Department of Radiation Oncology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea (I.H.K.).


Delayed posterior circulation insufficiency in pediatric moyamoya disease.
J Neurol 2014 Dec 12;261(12):2305-13. Epub 2014 Sep 12.
Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 110-744, Republic of Korea.


Regulation of keratinocyte differentiation by O-GlcNAcylation.
J Dermatol Sci 2014 Jul 30;75(1):10-5. Epub 2014 Apr 30.
Department of Dermatology and Research Institute for Medical Sciences, School of Medicine, Chungnam National University, Daejeon, Republic of Korea. Electronic address:

Involuntary movement in pediatric moyamoya disease patients: consideration of pathogenetic mechanism using neuroimaging studies.
Childs Nerv Syst 2014 May 12;30(5):885-90. Epub 2013 Dec 12.
Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul National University College of Medicine, Seoul, South Korea.

Cytogenetic prognostication within medulloblastoma subgroups.
J Clin Oncol 2014 Mar 3;32(9):886-96. Epub 2014 Feb 3.
David J.H. Shih, Marc Remke, Vijay Ramaswamy, Betty Luu, Yuan Yao, Xin Wang, Adrian M. Dubuc, Livia Garzia, John Peacock, Stephen C. Mack, Xiaochong Wu, Adi Rolider, A. Sorana Morrissy, Florence M.G. Cavalli, Claudia C. Faria, Stephen W. Scherer, Uri Tabori, Cynthia E. Hawkins, David Malkin, Eric Bouffet, James T. Rutka, and Michael D. Taylor, Hospital for Sick Children; David J.H. Shih, Marc Remke, Vijay Ramaswamy, Yuan Yao, Xin Wang, Adrian M. Dubuc, John Peacock, Stephen C. Mack, and Michael D. Taylor, University of Toronto, Toronto; Boleslaw Lach, McMaster University, Hamilton, Ontario; Jennifer A. Chan, University of Calgary, Calgary, Alberta; Steffen Albrecht, Adam Fontebasso, and Nada Jabado, McGill University, Montreal, Quebec, Canada; Paul A. Northcott, Andrey Korshunov, Marcel Kool, David T.W. Jones, and Stefan M. Pfister, German Cancer Research Center; Stefan M. Pfister, University Hospital Heidelberg, Heidelberg; Ulrich Schüller, Ludwig-Maximilians-University, Munich; Stefan Rutkowski, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Karel Zitterbart, Masaryk University School of Medicine; Karel Zitterbart and Leos Kren, University Hospital Brno, Brno, Czech Republic; Toshihiro Kumabe and Teiji Tominaga, Tohoku University Graduate School of Medicine, Sendai, Japan; Young Shin Ra, University of Ulsan, Asan Medical Center; Ji-Yeoun Lee, Byung-Kyu Cho, Seung-Ki Kim, and Kyu-Chang Wang, Seoul National University Children's Hospital, Seoul; Shin Jung, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital and Medical School, Chonnam, South Korea; Peter Hauser and Miklós Garami, Semmelweis University, Budapest; László Bognár and Almos Klekner, University of Debrecen, Medical and Health Science Centre, Debrecen, Hungary; Shenandoah Robinson, Boston Children's Hospital; Scott L. Pomeroy, Harvard Medical School, Boston, MA; Ali G. Saad, University of Arkansas for Medical Sciences, Little

Clinical outcome of pediatric choroid plexus tumors: retrospective analysis from a single institute.
Childs Nerv Syst 2014 Feb 14;30(2):217-25. Epub 2013 Jul 14.
Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 110-744, Republic of Korea.

Identification of brain tumour initiating cells using the stem cell marker aldehyde dehydrogenase.
Eur J Cancer 2014 Jan 5;50(1):137-49. Epub 2013 Oct 5.
Division of Pediatric Neurosurgery, Pediatric Clinical Neuroscience Center, Seoul National University Children's Hospital, Republic of Korea; Adolescent Cancer Center, Seoul National University Cancer Hospital, Republic of Korea; Department of Neurosurgery, Seoul National University Hospital, College of Medicine, Seoul, Republic of Korea. Electronic address:

Posterior cerebral artery involvement in moyamoya disease: initial infarction and angle between PCA and basilar artery.
Childs Nerv Syst 2013 Dec 8;29(12):2263-9. Epub 2013 May 8.
Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 110-744, Republic of Korea.

Pathoembryogenesis of terminal myelocystocele: terminal balloon in secondary neurulation of the chick embryo.
Childs Nerv Syst 2013 Sep 19;29(9):1683-8. Epub 2013 Jun 19.
Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 110-769, Republic of Korea.

Atypical teratoid/rhabdoid tumors: the need for more active therapeutic measures in younger patients.
J Neurooncol 2012 Apr 2;107(2):413-9. Epub 2011 Dec 2.
Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 110-744, Republic of Korea.

Human Adipose Tissue-Derived Mesenchymal Stem Cells Target Brain Tumor-Initiating Cells.
PLoS One 2015 15;10(6):e0129292. Epub 2015 Jun 15.
Division of Pediatric Neurosurgery, Pediatric Clinical Neuroscience Center, Seoul National University Children's Hospital, College of Medicine, Seoul, Korea; Adolescent Cancer Center, Seoul National University Cancer Hospital, Seoul, Korea.


Preclinical Biosafety Evaluation of Genetically Modified Human Adipose Tissue-Derived Mesenchymal Stem Cells for Clinical Applications to Brainstem Glioma.
Stem Cells Dev 2016 06 6;25(12):897-908. Epub 2016 Jun 6.
1 Division of Pediatric Neurosurgery, Pediatric Clinical Neuroscience Center, Seoul National University Children's Hospital, Seoul National University College of Medicine , Seoul, Korea.

Chemokine Ligand 5 (CCL5) Derived from Endothelial Colony-Forming Cells (ECFCs) Mediates Recruitment of Smooth Muscle Progenitor Cells (SPCs) toward Critical Vascular Locations in Moyamoya Disease.
PLoS One 2017 10;12(1):e0169714. Epub 2017 Jan 10.
Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.

A Case of Pulmonary Langerhans Cell Sarcoma Simultaneously Diagnosed with Cutaneous Langerhans Cell Histiocytosis Studied by Whole-Exome Sequencing.
Acta Haematol 2017 15;138(1):24-30. Epub 2017 Jun 15.
Department of Thoracic and Cardiovascular Surgery, Chungbuk National University College of Medicine, Cheongju, Republic of Korea.

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