Publications by authors named "Ji Hong Lim"

56Publications

Molecular Targeting of VEGF with a Suramin Fragment-DOCA Conjugate by Mimicking the Action of Low Molecular Weight Heparins.

Authors:
Jooho Park Tae-Bong Kang Ji-Hong Lim Hyung-Sik Won

Biomolecules 2020 Dec 31;11(1). Epub 2020 Dec 31.

Department of Biotechnology, College of Biomedical & Health Science, Konkuk University, Chungju 27478, Korea.

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December 2020

Cinobufagin Suppresses Melanoma Cell Growth by Inhibiting LEF1.

Authors:
Geon-Hee Kim Xue-Quan Fang Woo-Jin Lim Jooho Park Tae-Bong Kang Ji Hyung Kim Ji-Hong Lim

Int J Mol Sci 2020 Sep 13;21(18). Epub 2020 Sep 13.

Department of Biomedical Chemistry, College of Biomedical & Health Science, Konkuk University, Chungju 27478, Korea.

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September 2020

Ursolic Acid Suppresses Cholesterol Biosynthesis and Exerts Anti-Cancer Effects in Hepatocellular Carcinoma Cells.

Authors:
Geon-Hee Kim Sang-Yeon Kan Hyeji Kang Sujin Lee Hyun Myung Ko Ji Hyung Kim Ji-Hong Lim

Int J Mol Sci 2019 Sep 26;20(19). Epub 2019 Sep 26.

Department of Applied Life Science, Graduate School of Konkuk University, College of Biomedical & Health Science, Konkuk University, Chungju 27478, Korea.

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September 2019

HSF1 Regulates Mevalonate and Cholesterol Biosynthesis Pathways.

Authors:
Hyeji Kang Taerim Oh Young Yil Bahk Geon-Hee Kim Sang-Yeon Kan Dong Hoon Shin Ji Hyung Kim Ji-Hong Lim

Cancers (Basel) 2019 Sep 13;11(9). Epub 2019 Sep 13.

Department of Applied Life Sciences, Graduate School of Konkuk University, College of Biomedical & Health Science, Konkuk University, Chungju 27478, Chungbuk, Korea.

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September 2019

IDH1 Causes Resistance to HDAC Inhibitors by Increasing NANOG in Glioblastoma Cells.

Authors:
Geon-Hee Kim So Young Choi Taek-In Oh Sang-Yeon Kan Hyeji Kang Sujin Lee Taerim Oh Hyun Myung Ko Ji-Hong Lim

Int J Mol Sci 2019 May 31;20(11). Epub 2019 May 31.

Department of Applied Life Science, Graduate School of Konkuk University, College of Biomedical & Health Science, Konkuk University, Chungju 27478, Chungbuk, Korea.

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May 2019

Thymoquinone Selectively Kills Hypoxic Renal Cancer Cells by Suppressing HIF-1α-Mediated Glycolysis.

Authors:
Yoon-Mi Lee Geon-Hee Kim Eun-Ji Park Taek-In Oh Sujin Lee Sang-Yeon Kan Hyeji Kang Byeong Mo Kim Ji Hyung Kim Ji-Hong Lim

Int J Mol Sci 2019 Mar 3;20(5). Epub 2019 Mar 3.

Department of Biomedical Chemistry, College of Biomedical & Health Science, Konkuk University, Chungju 27478, Korea.

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March 2019

Acquired diffuse slate-grey facial dyspigmentation due to henna: an unrecognized cause of pigment contact dermatitis in Korean patients.

Authors:
Yu Ri Woo Jong Sic Kim Ji Hong Lim Jin Young Choi Miri Kim Dong Soo Yu Young Min Park Hyun Jeong Park

Eur J Dermatol 2018 Oct;28(5):644-648

Department of Dermatology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

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October 2018

Zerumbone, a Tropical Ginger Sesquiterpene of Roscoe, Attenuates α-MSH-Induced Melanogenesis in B16F10 Cells.

Authors:
Taek-In Oh Hye-Jeong Jung Yoon-Mi Lee Sujin Lee Geon-Hee Kim Sang-Yeon Kan Hyeji Kang Taerim Oh Hyun Myung Ko Keun-Chang Kwak Ji-Hong Lim

Int J Mol Sci 2018 Oct 13;19(10). Epub 2018 Oct 13.

Department of Biomedical Chemistry, College of Biomedical & Health Science, Konkuk University, Chungju 27478, Chungbuk, Korea.

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October 2018

Emodin Sensitizes Hepatocellular Carcinoma Cells to the Anti-Cancer Effect of Sorafenib through Suppression of Cholesterol Metabolism.

Authors:
Young-Seon Kim Yoon-Mi Lee Taek-In Oh Dong Hoon Shin Geon-Hee Kim Sang-Yeon Kan Hyeji Kang Ji Hyung Kim Byeong Mo Kim Woo Jong Yim Ji-Hong Lim

Int J Mol Sci 2018 Oct 12;19(10). Epub 2018 Oct 12.

Department of Biomedical Chemistry, College of Biomedical & Health Science, Konkuk University, Chungju 27478, Chungbuk, Korea.

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October 2018

A Case of Stevens-Johnson Syndrome Probably Induced by Herbal Medicine.

Authors:
Ji Hong Lim Sang Hyun Cho Jeong Deuk Lee Hei Sung Kim

Ann Dermatol 2018 Aug 27;30(4):481-483. Epub 2018 Jun 27.

Department of Dermatology, The Catholic University of Korea, Incheon St. Mary's Hospital, Seoul, Korea.

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August 2018

The Effects of Aronia melanocarpa 'Viking' Extracts in Attenuating RANKL-Induced Osteoclastic Differentiation by Inhibiting ROS Generation and c-FOS/NFATc1 Signaling.

Authors:
Mithun Ghosh In Sook Kim Young Min Lee Seong Min Hong Taek Hwan Lee Ji Hong Lim Trishna Debnath Beong Ou Lim

Molecules 2018 Mar 8;23(3). Epub 2018 Mar 8.

Department of Applied Life Science, College of Biomedical & Health Science, Konkuk University, Chungju-si, Chungcheongbuk-do 27478, Korea.

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March 2018

Fascaplysin Sensitizes Anti-Cancer Effects of Drugs Targeting AKT and AMPK.

Authors:
Taek-In Oh Jun Ho Lee Seongman Kim Taek-Jin Nam Young-Seon Kim Byeong Mo Kim Woo Jong Yim Ji-Hong Lim

Molecules 2017 Dec 24;23(1). Epub 2017 Dec 24.

Department of Biomedical Chemistry, College of Biomedical & Health Science, Konkuk University, Chungju 27478, Chungbuk, Korea.

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December 2017

Caspase-4 is essential for saikosaponin a-induced apoptosis acting upstream of caspase-2 and γ-H2AX in colon cancer cells.

Authors:
Su Jin Kang Young Joon Lee Sung Gu Kang Soyoung Cho Wonsuck Yoon Ji Hong Lim Sang-Hyun Min Tae Ho Lee Byeong Mo Kim

Oncotarget 2017 Nov 1;8(59):100433-100448. Epub 2017 Nov 1.

Severance Integrative Research Institute for Cerebral & Cardiovascular Diseases (SIRIC), Yonsei University College of Medicine, Seodaemun-gu, Seoul 03722, Republic of Korea.

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November 2017

Prevalence and clinicopathologic characteristics of multiple myeloma with cutaneous involvement: A case series from Korea.

Authors:
Yu Ri Woo Jong Sic Kim Ji Hong Lim Sewon Hwang Miri Kim Jung Min Bae Young Min Park Chang-Ki Min Dong-Wook Kim Hyun Jeong Park

J Am Acad Dermatol 2018 03 6;78(3):471-478.e4. Epub 2017 Nov 6.

Department of Dermatology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. Electronic address:

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March 2018

Fascaplysin Exerts Anti-Cancer Effects through the Downregulation of Survivin and HIF-1α and Inhibition of VEGFR2 and TRKA.

Authors:
Taek-In Oh Yoon-Mi Lee Taek-Jin Nam Young-San Ko Shinmee Mah Jinhee Kim Younghoon Kim Rallabandi Harikrishna Reddy Young Jun Kim Sungwoo Hong Ji-Hong Lim

Int J Mol Sci 2017 Sep 29;18(10). Epub 2017 Sep 29.

Department of Biomedical Chemistry, College of Biomedical & Health Science, Konkuk University, Chungju 27478, Chungbuk, Korea.

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September 2017

Role of Protein Kinases and Their Inhibitors in Radiation Response of Tumor Cells.

Authors:
Byeong Mo Kim Wonsuck Yoon Jung-Hyun Shim Haiyoung Jung Ji Hong Lim Hyun-Jung Choi MiRan Seo Tae Ho Lee Sang-Hyun Min

Curr Pharm Des 2017 11;23(29):4259-4280

New Drug Development Center, DGMIF, 80 Chumbok-ro, Dong-gu, Daegu 41061, Korea.

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November 2017

Inhibition of NAT10 Suppresses Melanogenesis and Melanoma Growth by Attenuating Microphthalmia-Associated Transcription Factor (MITF) Expression.

Authors:
Taek-In Oh Yoon-Mi Lee Beong-Ou Lim Ji-Hong Lim

Int J Mol Sci 2017 Sep 7;18(9). Epub 2017 Sep 7.

Department of Biomedical Chemistry, College of Biomedical & Health Science, Konkuk University, Chungju 27478, Chungbuk, Korea.

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September 2017

Analysis of apoptosis-associated molecules Erythroid differentiation regulator 1, bcl-2 and p53 in actinic keratosis after treatment with ingenol mebutate.

Authors:
Yu Ri Woo Ji Hong Lim Seo-Won Jeong Dae Ho Cho Hyun Jeong Park

Exp Dermatol 2017 11 3;26(11):1012-1017. Epub 2017 Jul 3.

Department of Dermatology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

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November 2017

Vanillin Suppresses Cell Motility by Inhibiting STAT3-Mediated HIF-1α mRNA Expression in Malignant Melanoma Cells.

Authors:
Eun-Ji Park Yoon-Mi Lee Taek-In Oh Byeong Mo Kim Beong-Ou Lim Ji-Hong Lim

Int J Mol Sci 2017 Mar 1;18(3). Epub 2017 Mar 1.

Department of Biomedical Chemistry, College of Biomedical & Health Science, Konkuk University, Chungju 380-701, Korea.

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March 2017

Plumbagin Suppresses α-MSH-Induced Melanogenesis in B16F10 Mouse Melanoma Cells by Inhibiting Tyrosinase Activity.

Authors:
Taek-In Oh Jeong-Mi Yun Eun-Ji Park Young-Seon Kim Yoon-Mi Lee Ji-Hong Lim

Int J Mol Sci 2017 Feb 3;18(2). Epub 2017 Feb 3.

Department of Biomedical Chemistry, College of Biomedical and Health Science, Konkuk University, Chungju 380-701, Korea.

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February 2017

Rosacea: Molecular Mechanisms and Management of a Chronic Cutaneous Inflammatory Condition.

Authors:
Yu Ri Woo Ji Hong Lim Dae Ho Cho Hyun Jeong Park

Int J Mol Sci 2016 Sep 15;17(9). Epub 2016 Sep 15.

Department of Dermatology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 07345, Korea.

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September 2016

A PGC1α-mediated transcriptional axis suppresses melanoma metastasis.

Authors:
Chi Luo Ji-Hong Lim Yoonjin Lee Scott R Granter Ajith Thomas Francisca Vazquez Hans R Widlund Pere Puigserver

Nature 2016 09 31;537(7620):422-426. Epub 2016 Aug 31.

Department of Cancer Biology, Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.

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September 2016

Linear acanthosis nigricans on the anterior neck: Koebner phenomenon observed in a patient with acanthosis nigricans.

Authors:
Yu Ri Woo Ji Hong Lim Miri Kim Hyun Jeong Park

J Dermatol 2017 Jul 29;44(7):843-845. Epub 2016 Aug 29.

Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.

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July 2017

Preventive and therapeutic effects of blueberry (Vaccinium corymbosum) extract against DSS-induced ulcerative colitis by regulation of antioxidant and inflammatory mediators.

Authors:
Mehnaz Pervin Md Abul Hasnat Ji-Hong Lim Yoon-Mi Lee Eun Ok Kim Byung-Hun Um Beong Ou Lim

J Nutr Biochem 2016 Feb 26;28:103-13. Epub 2015 Oct 26.

College of Biomedical & Health Science, Department of Life Science, Konkuk University, Chungju, 380-701, Republic of Korea. Electronic address:

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February 2016

Small-molecule inhibitors of USP7 induce apoptosis through oxidative and endoplasmic reticulum stress in cancer cells.

Authors:
Gibok Lee Taek-In Oh Ki Bum Um Hyeshin Yoon Jaekyoung Son Byeong Mo Kim Hong-Il Kim Hackyoung Kim Young Jun Kim Chang-Soo Lee Ji-Hong Lim

Biochem Biophys Res Commun 2016 Jan 6;470(1):181-186. Epub 2016 Jan 6.

Department of Biomedical Chemistry, College of Biomedical & Health Science, Konkuk University, Chungju 380-701, Chungbuk, Republic of Korea. Electronic address:

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January 2016

Oxidative Dimerization of PHD2 is Responsible for its Inactivation and Contributes to Metabolic Reprogramming via HIF-1α Activation.

Authors:
Gibok Lee Hyung-Sik Won Yoon-Mi Lee Jae-Wan Choi Taek-In Oh Jeong-Hwa Jang Dong-Kug Choi Beong-Ou Lim Young Jun Kim Jong-Wan Park Pere Puigserver Ji-Hong Lim

Sci Rep 2016 Jan 7;6:18928. Epub 2016 Jan 7.

Department of Biomedical Chemistry, College of Biomedical &Health Science, Konkuk University, Chungju 380-701, Chungbuk, Republic of Korea.

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January 2016

A potential therapeutic effect of saikosaponin C as a novel dual-target anti-Alzheimer agent.

Authors:
Tae Ho Lee Sungha Park Mi-Hyeon You Ji-Hong Lim Sang-Hyun Min Byeong Mo Kim

J Neurochem 2016 Mar 21;136(6):1232-1245. Epub 2016 Jan 21.

Severance Integrative Research Institute for Cerebral & Cardiovascular Diseases (SIRIC), Yonsei University College of Medicine, Seoul, Korea.

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March 2016

Apigenin Attenuates Melanoma Cell Migration by Inducing Anoikis through Integrin and Focal Adhesion Kinase Inhibition.

Authors:
Md Abul Hasnat Mehnaz Pervin Ji Hong Lim Beong Ou Lim

Molecules 2015 Nov 27;20(12):21157-66. Epub 2015 Nov 27.

Department of Life Sciences, College of Biomedical & Health Science, Konkuk University, Chungju 380-701, Korea.

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November 2015

Inhibition of glutamine utilization sensitizes lung cancer cells to apigenin-induced apoptosis resulting from metabolic and oxidative stress.

Authors:
Yoon-Mi Lee Gibok Lee Taek-In Oh Byeong Mo Kim Do-Wan Shim Kwang-Ho Lee Young Jun Kim Beong Ou Lim Ji-Hong Lim

Int J Oncol 2016 Jan 11;48(1):399-408. Epub 2015 Nov 11.

Department of Biomedical Chemistry, College of Biomedical and Health Science, Konkuk University, Chungbuk, Chungju 380-701, Republic of Korea.

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January 2016

Therapeutic Implications for Overcoming Radiation Resistance in Cancer Therapy.

Authors:
Byeong Mo Kim Yunkyung Hong Seunghoon Lee Pengda Liu Ji Hong Lim Yong Heon Lee Tae Ho Lee Kyu Tae Chang Yonggeun Hong

Int J Mol Sci 2015 Nov 10;16(11):26880-913. Epub 2015 Nov 10.

Department of Physical Therapy, College of Biomedical Science & Engineering, Inje University, Gimhae 50834, Korea.

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November 2015

Differential regulation of HIF-3α in LPS-induced BV-2 microglial cells: Comparison and characterization with HIF-1α.

Authors:
Hemant Kumar Ji-Hong Lim In-Su Kim Dong-Kug Choi

Brain Res 2015 Jun 3;1610:33-41. Epub 2015 Apr 3.

(a)Department of Biotechnology, Konkuk University, Chungju-si 380-701, Republic of Korea. Electronic address:

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June 2015

Attenuation of inflammatory-mediated neurotoxicity by Saururus chinensis extract in LPS-induced BV-2 microglia cells via regulation of NF-κB signaling and anti-oxidant properties.

Authors:
Byung-Wook Kim Sushruta Koppula Shin-Young Park Jin-Woo Hwang Pyo-Jam Park Ji-Hong Lim Dong-Kug Choi

BMC Complement Altern Med 2014 Dec 16;14:502. Epub 2014 Dec 16.

Department of Biotechnology, Konkuk University, Chungju, Korea.

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December 2014

Attenuation of neuroinflammatory responses and behavioral deficits by Ligusticum officinale (Makino) Kitag in stimulated microglia and MPTP-induced mouse model of Parkinson's disease.

Authors:
Byung-Wook Kim Sushruta Koppula Shin-Young Park Yon-Suk Kim Pyo-Jam Park Ji-Hong Lim In-Su Kim Dong-Kug Choi

J Ethnopharmacol 2015 Apr 11;164:388-97. Epub 2014 Nov 11.

Department of Biotechnology, Konkuk University, Chungju, Korea. Electronic address:

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April 2015

Inhibition of the Interleukin-11-STAT3 Axis Attenuates Hypoxia-Induced Migration and Invasion in MDA-MB-231 Breast Cancer Cells.

Authors:
Ji-Hong Lim

Korean J Physiol Pharmacol 2014 Oct 17;18(5):391-6. Epub 2014 Oct 17.

Department of Biomedical Chemistry, College of Biomedical & Health Science, Konkuk University, Chungju 380-701, Korea.

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October 2014

PRMT5 is essential for the eIF4E-mediated 5'-cap dependent translation.

Authors:
Ji-Hong Lim Yoon-Mi Lee Gibok Lee Yong-Joon Choi Beong-Ou Lim Young Jun Kim Dong-Kug Choi Jong-Wan Park

Biochem Biophys Res Commun 2014 Oct 16;452(4):1016-21. Epub 2014 Sep 16.

Departments of Pharmacology and Biomedical Science, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul 110-799, Republic of Korea. Electronic address:

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October 2014

Anticancer activity of hispidin via reactive oxygen species-mediated apoptosis in colon cancer cells.

Authors:
Ji-Hong Lim Yoon-Mi Lee Sa Ra Park Da Hye Kim Beong Ou Lim

Anticancer Res 2014 Aug;34(8):4087-93

Department of Applied Biochemistry, College of Biomedical & Health Science, Research Institute of Inflammatory Disease, Konkuk University, Chungju, South Korea

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August 2014

Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression.

Authors:
Yoonjin Lee John E Dominy Yoon Jong Choi Michael Jurczak Nicola Tolliday Joao Paulo Camporez Helen Chim Ji-Hong Lim Hai-Bin Ruan Xiaoyong Yang Francisca Vazquez Piotr Sicinski Gerald I Shulman Pere Puigserver

Nature 2014 Jun 25;510(7506):547-51. Epub 2014 May 25.

1] Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA [2] Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.

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June 2014

Zinc finger and BTB domain-containing protein 3 is essential for the growth of cancer cells.

Authors:
Ji-Hong Lim

BMB Rep 2014 Jul;47(7):405-10

Department of Biomedical Chemistry, College of Biomedical and Health Science, Konkuk University, Chungju 380-701, Korea.

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July 2014

Targeting mitochondrial oxidative metabolism in melanoma causes metabolic compensation through glucose and glutamine utilization.

Authors:
Ji-Hong Lim Chi Luo Francisca Vazquez Pere Puigserver

Cancer Res 2014 Jul 8;74(13):3535-45. Epub 2014 May 8.

Authors' Affiliations: Department of Cancer Biology, Dana-Farber Cancer Institute; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts; and

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July 2014

PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress.

Authors:
Francisca Vazquez Ji-Hong Lim Helen Chim Kavita Bhalla Geoff Girnun Kerry Pierce Clary B Clish Scott R Granter Hans R Widlund Bruce M Spiegelman Pere Puigserver

Cancer Cell 2013 Mar 14;23(3):287-301. Epub 2013 Feb 14.

Department of Cancer Biology, Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.

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March 2013

Oleic acid stimulates complete oxidation of fatty acids through protein kinase A-dependent activation of SIRT1-PGC1α complex.

Authors:
Ji-Hong Lim Zachary Gerhart-Hines John E Dominy Yoonjin Lee Sungjin Kim Mitsuhisa Tabata Yang K Xiang Pere Puigserver

J Biol Chem 2013 Mar 17;288(10):7117-26. Epub 2013 Jan 17.

Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.

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March 2013

Protein arginine methyltransferase 5 is an essential component of the hypoxia-inducible factor 1 signaling pathway.

Authors:
Ji-Hong Lim Yong-Joon Choi Chung-Hyun Cho Jong-Wan Park

Biochem Biophys Res Commun 2012 Feb 9;418(2):254-9. Epub 2012 Jan 9.

Department of Pharmacology, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul 110-799, Republic of Korea.

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February 2012

The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD(+).

Authors:
Zachary Gerhart-Hines John E Dominy Sharon M Blättler Mark P Jedrychowski Alexander S Banks Ji-Hong Lim Helen Chim Steven P Gygi Pere Puigserver

Mol Cell 2011 Dec;44(6):851-63

Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.

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December 2011

CITED2 controls the hypoxic signaling by snatching p300 from the two distinct activation domains of HIF-1α.

Authors:
Haejin Yoon Ji-Hong Lim Chung-Hyun Cho L Eric Huang Jong-Wan Park

Biochim Biophys Acta 2011 Dec 8;1813(12):2008-16. Epub 2011 Sep 8.

Department of Pharmacology, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Chongno-gu, Seoul, Republic of Korea.

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December 2011

von Hippel-Lindau protein adjusts oxygen sensing of the FIH asparaginyl hydroxylase.

Authors:
Shan Hua Li Yang-Sook Chun Ji-Hong Lim L Eric Huang Jong-Wan Park

Int J Biochem Cell Biol 2011 May 21;43(5):795-804. Epub 2011 Feb 21.

Department of Pharmacology, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul 110-799, Republic of Korea.

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May 2011

Antihepatoma activity of chaetocin due to deregulated splicing of hypoxia-inducible factor 1α pre-mRNA in mice and in vitro.

Authors:
Yoon-Mi Lee Ji-Hong Lim Haejin Yoon Yang-Sook Chun Jong-Wan Park

Hepatology 2011 Jan 7;53(1):171-80. Epub 2010 Dec 7.

Department of Pharmacology, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, Korea.

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January 2011

CAML promotes prolactin-dependent proliferation of breast cancer cells by facilitating prolactin receptor signaling pathways.

Authors:
Ji-hong Lim Tae-you Kim Woo-ho Kim Jong-wan Park

Breast Cancer Res Treat 2011 Nov 3;130(1):19-27. Epub 2010 Dec 3.

Department of Pharmacology, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, 110-799, Korea.

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November 2011

Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha.

Authors:
Ji-Hong Lim Yoon-Mi Lee Yang-Sook Chun Junjie Chen Ja-Eun Kim Jong-Wan Park

Mol Cell 2010 Jun;38(6):864-78

Department of Pharmacology, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul 110-799, Korea.

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June 2010

Nutlin-3, an Hdm2 antagonist, inhibits tumor adaptation to hypoxia by stimulating the FIH-mediated inactivation of HIF-1alpha.

Authors:
Yoon-Mi Lee Ji-Hong Lim Yang-Sook Chun Hyo-Eun Moon Myung Kyu Lee L Eric Huang Jong-Wan Park

Carcinogenesis 2009 Oct 20;30(10):1768-75. Epub 2009 Aug 20.

Department of Pharmacology, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, Korea.

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October 2009

Reactive oxygen species-mediated cyclin D1 degradation mediates tumor growth retardation in hypoxia, independently of p21cip1 and hypoxia-inducible factor.

Authors:
Ji-Hong Lim Yoon-Mi Lee Yang-Sook Chun Jong-Wan Park

Cancer Sci 2008 Sep 4;99(9):1798-805. Epub 2008 Jul 4.

Department of Pharmacology, Seoul National University College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul 110-799, Korea.

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September 2008

Hypoxia-inducible factor-1alpha obstructs a Wnt signaling pathway by inhibiting the hARD1-mediated activation of beta-catenin.

Authors:
Ji-Hong Lim Yang-Sook Chun Jong-Wan Park

Cancer Res 2008 Jul;68(13):5177-84

Department of Pharmacology, Seoul National University College of Medicine, Chongno-gu, Seoul, Korea.

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July 2008

The high contrast ratio and fast response time of a liquid crystal display lit by a carbon nanotube field emission backlight unit.

Authors:
Young Chul Choi Ji Won Lee Su Kyung Lee Mun Seok Kang Chang Soo Lee Kyu Won Jung Ji Hong Lim Jong Woon Moon Myung Ick Hwang Il Hwan Kim Yun Hee Kim Byong Gon Lee Hyung Rae Seon Sang Jin Lee Jong Hwan Park Yong C Kim Hun Soo Kim

Nanotechnology 2008 Jun 6;19(23):235306. Epub 2008 May 6.

Display Laboratory 3 Group, Corporate R&D Center, Samsung SDI, 428-5, Gongse-dong, Giheung-gu, Yongin, Gyeonggi 446-577, Republic of Korea.

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June 2008

ATP6V0C competes with von Hippel-Lindau protein in hypoxia-inducible factor 1alpha (HIF-1alpha) binding and mediates HIF-1alpha expression by bafilomycin A1.

Authors:
Ji-Hong Lim Jong-Wan Park Sung Joon Kim Myung-Suk Kim Sang-Ki Park Randall S Johnson Yang-Sook Chun

Mol Pharmacol 2007 Mar 18;71(3):942-8. Epub 2006 Dec 18.

Cancer Research Institute, Seoul National University College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul 110-799, Korea.

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March 2007

Human arrest defective 1 acetylates and activates beta-catenin, promoting lung cancer cell proliferation.

Authors:
Ji-Hong Lim Jong-Wan Park Yang-Sook Chun

Cancer Res 2006 Nov;66(22):10677-82

Cancer Research Institute and Departments of Pharmacology and Physiology, Seoul National University College of Medicine, Seoul, Korea.

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November 2006

Bafilomycin induces the p21-mediated growth inhibition of cancer cells under hypoxic conditions by expressing hypoxia-inducible factor-1alpha.

Authors:
Ji-Hong Lim Jong-Wan Park Myung-Suk Kim Sang-Ki Park Randall S Johnson Yang-Sook Chun

Mol Pharmacol 2006 Dec 28;70(6):1856-65. Epub 2006 Aug 28.

Cancer Research Institute, Seoul National University College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul 110-799, Korea.

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December 2006

Ras-dependent induction of HIF-1alpha785 via the Raf/MEK/ERK pathway: a novel mechanism of Ras-mediated tumor promotion.

Authors:
Ji-Hong Lim Eun-Seo Lee Ho-Jin You Jung Weon Lee Jong-Wan Park Yang-Sook Chun

Oncogene 2004 Dec;23(58):9427-31

Human Genome Research Institute and Cancer Research Institute, Seoul National University College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul 110-799, Korea.

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December 2004