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[The importance of socioeconomic factors in obesity studies. Authors reply].

An Pediatr (Barc) 2019 12 19;91(6):424. Epub 2019 Jul 19.

Servicio de Endocrinología, Hospital Infantil Universitario Niño Jesús, Madrid, España; Departamento de Pediatría, Universidad Autónoma de Madrid, Madrid, España; Instituto Madrileño de Estudios Avanzados (IMDEA), Madrid, España.

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http://dx.doi.org/10.1016/j.anpedi.2019.06.007DOI Listing
December 2019

Sex, puberty, and ethnicity have a strong influence on growth and metabolic comorbidities in children and adolescents with obesity: Report on 1300 patients (the Madrid Cohort).

Pediatr Obes 2019 Dec 2;14(12):e12565. Epub 2019 Aug 2.

Department of Endocrinology, Research Institute "La Princesa", Hospital Infantil Universitario Niño Jesús, Avenida Menéndez Pelayo, 65E-28009, Madrid, Spain.

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http://dx.doi.org/10.1111/ijpo.12565DOI Listing
December 2019

New insulin delivery devices and glycemic outcomes in young patients with type 1 diabetes: a protocol for a systematic review and meta-analysis.

Syst Rev 2019 Nov 4;8(1):259. Epub 2019 Nov 4.

Department of Preventive Medicine and Public Health. School of Medicine, Universidad Autónoma de Madrid/IdiPAZ, Madrid, Spain.

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http://dx.doi.org/10.1186/s13643-019-1171-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829915PMC
November 2019

LZTR1: Genotype Expansion in Noonan Syndrome.

Horm Res Paediatr 2019 Sep 18:1-7. Epub 2019 Sep 18.

Departments of Pediatrics and Pediatric Endocrinology, Hospital Infantil Universitario Niño Jesús, Madrid, Spain,

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http://dx.doi.org/10.1159/000502741DOI Listing
September 2019

Genetics of Growth Disorders-Which Patients Require Genetic Testing?

Front Endocrinol (Lausanne) 2019 6;10:602. Epub 2019 Sep 6.

Department of Pediatrics, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.3389/fendo.2019.00602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742727PMC
September 2019

[Influence of neonatal anthropometry on the comorbidities of the obese patient].

An Pediatr (Barc) 2019 Jun 2;90(6):362-369. Epub 2018 Jul 2.

Servicio de Endocrinología, Hospital Infantil Universitario Niño Jesús, Madrid, España; Departamento de Pediatría, Universidad Autónoma de Madrid, Madrid, España; Centro de Investigación Biomédica Red-Fisiopatología de la Obesidad y la Nutrición (CIBERobn), Instituto de Salud Carlos III, Madrid, España. Electronic address:

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http://dx.doi.org/10.1016/j.anpedi.2018.05.017DOI Listing
June 2019

Perinatal free-choice of a high-calorie low-protein diet affects leptin signaling through IRS1 and AMPK dephosphorylation in the hypothalami of female rat offspring in adulthood.

Acta Physiol (Oxf) 2019 Jun 21;226(2):e13244. Epub 2019 Jan 21.

Unidad de Gestión Clínica de Salud Mental, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain.

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http://doi.wiley.com/10.1111/apha.13244
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http://dx.doi.org/10.1111/apha.13244DOI Listing
June 2019

Central precocious puberty, functional and tumor-related.

Best Pract Res Clin Endocrinol Metab 2019 06 22;33(3):101262. Epub 2019 Jan 22.

Department of Pediatrics, Universidad Autónoma de Madrid, Spain; Department of Pediatrics & Pediatric Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa, Madrid, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain; IMDEA Food Institute, CEIUAM+CSIC, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.beem.2019.01.003DOI Listing
June 2019

Improvement in inflammation is associated with the protective effect of Gly-Pro-Glu and cycloprolylglycine against Aβ-induced depletion of the hippocampal somatostatinergic system.

Neuropharmacology 2019 06 11;151:112-126. Epub 2019 Apr 11.

Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación Sanitaria La Princesa, Madrid, Spain; CIBER Fisiopatología Obesidad y Nutrición (CB06/03), Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2019.04.008DOI Listing
June 2019

Sex differences in the peripubertal response to a short-term, high-fat diet intake.

J Neuroendocrinol 2019 Jun 10:e12756. Epub 2019 Jun 10.

Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación la Princesa, Madrid, Spain.

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http://dx.doi.org/10.1111/jne.12756DOI Listing
June 2019

[Thickening of the pituitary stalk in children and adolescents with central diabetes insipidus: Causes and consequences].

An Pediatr (Barc) 2019 May 9;90(5):293-300. Epub 2018 Jun 9.

Servicio de Pediatría y Endocrinología, Hospital Infantil Universitario Niño Jesús, Madrid, España; Departamento de Pediatría, Universidad Autónoma de Madrid, Madrid, España; CIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, España.; IMDEA Instituto de Alimentación, CEI UAM + CSIC, Madrid, España.

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http://dx.doi.org/10.1016/j.anpedi.2018.05.002DOI Listing
May 2019

Neurobiological characteristics underlying metabolic differences between males and females.

Prog Neurobiol 2019 05 5;176:18-32. Epub 2018 Sep 5.

Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación la Princesa, Department of Pediatrics, Universidad Autónoma de Madrid, CIBEROBN (Centro de Investigación Biomédica en Red sobre Fisiopatología de la Obesidad y Nutrición), Instituto de Salud Carlos III. Madrid, Spain; IMDEA Food Institute, CEI UAM + CSIC, Madrid, Spain.

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https://linkinghub.elsevier.com/retrieve/pii/S03010082183008
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http://dx.doi.org/10.1016/j.pneurobio.2018.09.001DOI Listing
May 2019

[Parental obesity is associated with the severity of childhood obesity and its comorbidities].

An Pediatr (Barc) 2019 Apr 24;90(4):224-231. Epub 2018 Jul 24.

Servicio de Endocrinología, Hospital Infantil Universitario Niño Jesús, Madrid, España; Departamento de Pediatría, Universidad Autónoma de Madrid, Madrid, España; Centro de Investigación Biomédica en Red-Fisiopatología de la Obesidad y la Nutrición (CIBERobn), Instituto de Salud Carlos III, Madrid, España. Electronic address:

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http://dx.doi.org/10.1016/j.anpedi.2018.06.013DOI Listing
April 2019

Metabolomics changes in patients with PAPP-A2 deficiency in response to rhIGF1 treatment.

Growth Horm IGF Res 2018 Oct - Dec;42-43:28-31. Epub 2018 Aug 12.

Departments of Pediatrics & Pediatric Endocrinology, Hospital Infantil Universitario Niño Jesús, Madrid, Spain; La Princesa Research Institute, Madrid, Spain; Department of Pediatrics, Universidad Autónoma de Madrid, Madrid, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutriciόn (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain; IMDEA Food Institute, CEI UAM & CSIC, Madrid, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10966374183006
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http://dx.doi.org/10.1016/j.ghir.2018.08.002DOI Listing
March 2019

Heterozygous rare genetic variants in non-syndromic early-onset obesity.

Int J Obes (Lond) 2019 Mar 29. Epub 2019 Mar 29.

Hospital Infantil Universitario Niño Jesús, Department of Endocrinology, Instituto de Investigación La Princesa, Universidad Autónoma de Madrid, Department of Pediatrics, Avenida Menéndez Pelayo, 65, 28009, Madrid, Spain.

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http://dx.doi.org/10.1038/s41366-019-0357-5DOI Listing
March 2019

A novel GLI2 mutation responsible for congenital hypopituitarism and polymalformation syndrome.

Growth Horm IGF Res 2019 02 18;44:17-19. Epub 2018 Dec 18.

Hospital Infantil Universitario Niño Jesús, Departments of Pediatrics & Pediatric Endocrinology, Research Institute "La Princesa", Madrid, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutriciόn (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain; Universidad Autónoma de Madrid, Department of Pediatrics, Madrid, Spain; IMDEA, Food Institute, CEIUAM+CSI, Crta. de Cantoblanco, 8, 28049 Cantoblanco, Madrid, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10966374183008
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http://dx.doi.org/10.1016/j.ghir.2018.12.002DOI Listing
February 2019

[Giant breast fibroadenomas in adolescents: Diagnostic and therapeutic procedures].

An Pediatr (Barc) 2018 Dec 22;89(6):383-385. Epub 2018 May 22.

Servicio de Pediatría, Hospital Infantil Universitario Niño Jesús, Madrid, España; Servicio de Endocrinología, Hospital Infantil Universitario Niño Jesús, Madrid, España; Departamento de Pediatría, Universidad Autónoma de Madrid, Madrid, España; CIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, España; IMDEA Instituto de Alimentación, CEI UAM + CSIC, Madrid, España.

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http://dx.doi.org/10.1016/j.anpedi.2018.01.006DOI Listing
December 2018

[Bilateral pseudoangiomatous stromal hyperplasia of the breast].

An Pediatr (Barc) 2018 Nov 13;89(5):309-311. Epub 2018 Feb 13.

Servicios de Pediatría y Endocrinología, Hospital Infantil Universitario Niño Jesús, Madrid, España; Departamento de Pediatría, Universidad Autónoma de Madrid; CIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, España; IMDEA Instituto de Alimentación, CEI UAM+CSIC, Madrid, España.

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http://dx.doi.org/10.1016/j.anpedi.2017.12.011DOI Listing
November 2018

Nephrotic syndrome associated with severe hypertriglyceridemia in a pediatric patient: Questions.

Pediatr Nephrol 2018 11 12;33(11):2073-2074. Epub 2018 Mar 12.

Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.

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http://dx.doi.org/10.1007/s00467-018-3894-6DOI Listing
November 2018

Nephrotic syndrome associated with severe hypertriglyceridemia in a pediatric patient: Answers.

Pediatr Nephrol 2018 11 12;33(11):2075-2078. Epub 2018 Mar 12.

Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.

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http://dx.doi.org/10.1007/s00467-018-3919-1DOI Listing
November 2018

Frequent and Rare HABP2 Variants Are Not Associated with Increased Susceptibility to Familial Nonmedullary Thyroid Carcinoma in the Spanish Population.

Horm Res Paediatr 2018 12;89(6):397-407. Epub 2018 Jun 12.

Thyroid Molecular Laboratory, Institute for Medical and Molecular Genetics (INGEMM), IdiPAZ, La Paz University Hospital, Universidad Autónoma de Madrid, Madrid, Spain.

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http://dx.doi.org/10.1159/000487395DOI Listing
November 2018

rhIGF-1 Treatment Increases Bone Mineral Density and Trabecular Bone Structure in Children with PAPP-A2 Deficiency.

Horm Res Paediatr 2018 16;89(3):200-204. Epub 2018 Feb 16.

Department of Pediatrics and Pediatric Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa, Madrid, Spain.

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http://dx.doi.org/10.1159/000486336DOI Listing
September 2018

Genetic causes of proportionate short stature.

Best Pract Res Clin Endocrinol Metab 2018 08 6;32(4):499-522. Epub 2018 Jun 6.

Full Professor of Genetics. Genetics Unit, Universitat Pompeu Fabra, Barcelona, Spain, Hospital del Mar Research Institute (IMIM), Barcelona, Spain, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III, Barcelona, Spain, SA Clinical Genetics, Women's and Children's Hospital, North Adelaide, SA, Australia, Clinical Professor, University of Adelaide, SA, Australia.

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http://dx.doi.org/10.1016/j.beem.2018.05.012DOI Listing
August 2018

The increase in fiber size in male rat gastrocnemius after chronic central leptin infusion is related to activation of insulin signaling.

Mol Cell Endocrinol 2018 07 27;470:48-59. Epub 2017 Sep 27.

Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa, E-28009, Madrid, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, E-28009, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2017.09.029DOI Listing
July 2018

[Hypophosphatasia: Clinical manifestations, diagnostic recommendations and therapeutic options].

An Pediatr (Barc) 2018 Jun 16;88(6):356.e1-356.e11. Epub 2017 Jul 16.

Servicio de Endocrinología, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación Sanitaria La Princesa, Departamento de Pediatría, Universidad Autónoma de Madrid, CIBERobn, Instituto de Salud Carlos III, Madrid, España; Instituto de Alimentación IMDEA, CEI UAM+CSIC, Madrid, España.

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http://dx.doi.org/10.1016/j.anpedi.2017.06.004DOI Listing
June 2018

Letter to the Editor: History and clinical implications of PAPP-A2 in human growth: When reflecting on idiopathic short stature leads to a specific and new diagnosis: Understanding the concept of "low IGF-I availability".

Growth Horm IGF Res 2018 06 5;40:17-19. Epub 2018 Apr 5.

Genetics Unit, Universitat Pompeu Fabra, Barcelona, Spain; Hospital del Mar Research Institute (IMIM), Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III, Barcelona, Spain; SA Clinical Genetics, Women's and Children's Hospital, University of Adelaide, Adelaide, South Australia, Australia.

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http://dx.doi.org/10.1016/j.ghir.2018.04.001DOI Listing
June 2018

[Karyptype 48,XXXY/49,XXXXY and proximal radioulnar synostosis].

An Pediatr (Barc) 2018 May 24;88(5):282-284. Epub 2017 Jul 24.

Servicio de Endocrinología, Hospital Infantil Universitario Niño Jesús, Madrid, España; Departamento de Pediatría, Universidad Autónoma de Madrid, Madrid, España; CIBEROBN Instituto de Salud Carlos III, Madrid, España.

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http://dx.doi.org/10.1016/j.anpedi.2017.05.008DOI Listing
May 2018

Acquired partial lipodystrophy (Barraquer-Simons syndrome) and IgA nephropathy.

Nefrologia 2016 Sep - Oct;36(5):556-558. Epub 2016 May 30.

Departamento de Endocrinología Pediátrica, Hospital Infantil Universitario Niño Jesús, Madrid, España; Departamento de Anatomía Patológica, Hospital Infantil Universitario Niño Jesús, Madrid, España; Instituto de Investigación La Princesa, Madrid, España; Departamento de Pediatría, Universidad Autónoma de Madrid, Madrid, España; CIBEROBN, Instituto de Salud Carlos III, Madrid, España.

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http://dx.doi.org/10.1016/j.nefro.2016.03.003DOI Listing
April 2018

The Protective Effects of IGF-I against β-Amyloid-related Downregulation of Hippocampal Somatostatinergic System Involve Activation of Akt and Protein Kinase A.

Neuroscience 2018 03 3;374:104-118. Epub 2018 Feb 3.

Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación Sanitaria La Princesa, Madrid, Spain; CIBER Fisiopatología Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neuroscience.2018.01.041DOI Listing
March 2018

[Brachydactyly type C due to a nonsense mutation in the GDF5 gene].

An Pediatr (Barc) 2018 Feb 5;88(2):107-109. Epub 2017 Apr 5.

Servicios de Pediatría y Endocrinología, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa, Madrid, España; Universidad Autónoma de Madrid, Departamento de Pediatría, Madrid, España; CIBER Fisiopatología de la obesidad y nutrición, Instituto de Salud Carlos III, Madrid, España. Electronic address:

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http://dx.doi.org/10.1016/j.anpedi.2017.03.001DOI Listing
February 2018

Resveratrol Intake During Pregnancy and Lactation Modulates the Early Metabolic Effects of Maternal Nutrition Differently in Male and Female Offspring.

Endocrinology 2018 02;159(2):810-825

Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa, Madrid, Spain.

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http://dx.doi.org/10.1210/en.2017-00610DOI Listing
February 2018

Sex differences in the neuroendocrine control of metabolism and the implication of astrocytes.

Front Neuroendocrinol 2018 01 25;48:3-12. Epub 2017 May 25.

Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación la Princesa, 28009 Madrid, Spain; CIBEROBN (Centro de Investigación Biomédica en Red: Fisiopatología de la Obesidad y Nutrición), 28009 Madrid, Spain; Department of Pediatrics, Facultad de Medicina, Universidad Autónoma de Madrid, 28009 Madrid, Spain; IMDEA Food Institute, CEI UAM + CSIC, Carretera de Cantoblanco 8., 28049 Madrid, Spain.

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http://dx.doi.org/10.1016/j.yfrne.2017.05.003DOI Listing
January 2018

The Hypothalamic Inflammatory/Gliosis Response to Neonatal Overnutrition Is Sex and Age Dependent.

Endocrinology 2018 01;159(1):368-387

Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación la Princesa, Madrid, Spain.

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http://dx.doi.org/10.1210/en.2017-00539DOI Listing
January 2018

The impact of intrauterine and extrauterine weight gain in premature infants on later body composition.

Pediatr Res 2017 Oct 5;82(4):658-664. Epub 2017 Jul 5.

Department of Neonatology, Hospital Universitario La Paz, Red de Salud Materno Infantil y Desarrollo - SAMID, Universidad Autónoma de Madrid, Madrid, Spain.

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http://www.nature.com/doifinder/10.1038/pr.2017.123
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http://dx.doi.org/10.1038/pr.2017.123DOI Listing
October 2017

One level up: abnormal proteolytic regulation of IGF activity plays a role in human pathophysiology.

EMBO Mol Med 2017 10;9(10):1338-1345

Department of Molecular Biology & Genetics, Aarhus University, Aarhus C, Denmark.

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http://dx.doi.org/10.15252/emmm.201707950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623872PMC
October 2017

[Elevated thyroid hormone levels following low molecular weight heparin administration].

An Pediatr (Barc) 2017 Jul 21;87(1):50-51. Epub 2016 Oct 21.

Servicios de Pediatría y Endocrinología, Hospital Infantil Universitario Niño Jesús, Madrid, España; Departamento de Pediatría, Universidad Autónoma de Madrid, Madrid, España; CIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, España.

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http://dx.doi.org/10.1016/j.anpedi.2016.09.006DOI Listing
July 2017

Ghrelin: A Link Between Energy Homeostasis and the Immune System.

Endocrinology 2017 07;158(7):2077-2081

Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación la Princesa, 28009 Madrid, Spain.

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http://dx.doi.org/10.1210/en.2017-00350DOI Listing
July 2017

Changes in Body Mass Index in Girls with Idiopathic Central Precocious Puberty under Gonadotropin-Releasing Hormone Analogue Therapy: The Spanish Registry.

Horm Res Paediatr 2016 13;86(3):154-160. Epub 2016 Aug 13.

Pediatric Endocrine Department, Corporació Parc Taulí, Sabadell Hospital, Institut Universitari Parc Taulí, Universitat Autònoma de Barcelona (UAB), Cerdanyola del Vallès, Spain.

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http://dx.doi.org/10.1159/000448552DOI Listing
April 2017

Microglial Proliferation in Obesity: When, Where, Why, and What Does It Mean?

Diabetes 2017 04;66(4):804-805

Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación del Hospital de la Princesa, Centro de Investigación Biomédica en Red de Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, Spain.

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http://dx.doi.org/10.2337/dbi16-0073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360305PMC
April 2017

Non-Neuronal Cells in the Hypothalamic Adaptation to Metabolic Signals.

Front Endocrinol (Lausanne) 2017 21;8:51. Epub 2017 Mar 21.

Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación la Princesa, Madrid, Spain; Centro de Investigación Biomédica en Red: Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Madrid, Spain.

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http://dx.doi.org/10.3389/fendo.2017.00051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359311PMC
March 2017

[Persistent Müllerian duct syndrome due to a mutation in the anti-Müllerian hormone receptor gene (AMHR2)].

An Pediatr (Barc) 2017 Feb 22;86(2):94-95. Epub 2016 Jul 22.

Servicio de Pediatría, Hospital Infantil Universitario Niño Jesús, Madrid, España; Servicio de Endocrinología, Hospital Infantil Universitario Niño Jesús, Madrid, España; Departamento de Pediatría, Universidad Autónoma de Madrid, Madrid, España; CIBER Fisiopatología de la obesidad y nutrición, Instituto de Salud Carlos III, Madrid, España. Electronic address:

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http://dx.doi.org/10.1016/j.anpedi.2016.06.011DOI Listing
February 2017

Glial cells and energy balance.

J Mol Endocrinol 2017 01 18;58(1):R59-R71. Epub 2016 Nov 18.

Departments of Pediatrics & Pediatric EndocrinologyHospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa, Department of Pediatrics, Universidad Autónoma de Madrid, CIBEROBN, Instituto de Salud Carlos III, Madrid, Spain

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http://dx.doi.org/10.1530/JME-16-0182DOI Listing
January 2017

Blockage of neonatal leptin signaling induces changes in the hypothalamus associated with delayed pubertal onset and modifications in neuropeptide expression during adulthood in male rats.

Peptides 2016 12 14;86:63-71. Epub 2016 Oct 14.

Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación Sanitaria Princesa (IP), Madrid, Spain; CIBER Fisiopatología de Obesidad y Nutrición, Instituto Carlos III, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.peptides.2016.10.003DOI Listing
December 2016

[Mutation in RET gene: Prophylactic thyroidectomy and postoperative follow-up].

An Pediatr (Barc) 2016 Nov 19;85(5):266-267. Epub 2016 Jan 19.

Servicio de Endocrinología, Hospital Infantil Universitario Niño Jesús, Madrid, España; Departamento de Pediatría, Universidad Autónoma de Madrid, Madrid, España; Centro de Investigación Biomédica en Red sobre Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, España.

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http://dx.doi.org/10.1016/j.anpedi.2015.12.005DOI Listing
November 2016

Treatment With Recombinant Human Insulin-Like Growth Factor-1 Improves Growth in Patients With PAPP-A2 Deficiency.

J Clin Endocrinol Metab 2016 Nov 20;101(11):3879-3883. Epub 2016 Sep 20.

Department of Pediatrics and Pediatric Endocrinology (M.T.M.-C., V.B., J.P., J.A.C., G.A.M.-M., J.A.) Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa, Universidad Autónoma de Madrid, Department of Pediatrics, Centro de Investigación Biomédica en Red (CIBEROBN), Instituto de Salud Carlos III, 28009 Madrid, Spain; Department of Endocrinology (F.H.), Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, 28040 Madrid, Spain; Cincinnati Center for Growth Disorders (A.D.), Division of Endocrinology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229; Centro de Investigaciones Endocrinológicas "Dr. César Bergadá" (CEDIE) (H.M.D.), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), FEI, División de Endocrinología, Hospital de Niños Ricardo Gutiérrez, C1425EFD Buenos Aires, Argentina; Department of Basic Science and Craniofacial Biology (S.Y.), New York University College of Dentistry, New York, New York 10010; Oregon Health and Science University (R.G.R.), Portland, Oregon 97239; Stat5 LLC (R.G.R.), Los Altos, California 94022; Genetics Unit (L.A.P.-J.), Universitat Pompeu Fabra, Hospital del Mar Research Institute (IMIM), and CIBER de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III, 08003 Barcelona, Spain; Department of Molecular Biology and Genetics (C.O.), Aarhus University, 8000 Aarhus, Denmark; and Medical Research Laboratory (J.F.), Department of Clinical Medicine, Faculty of Health, Aarhus University and Department of Endocrinology and Internal Medicine, Aarhus University Hospital, 8000 Aarhus, Denmark.

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http://dx.doi.org/10.1210/jc.2016-2751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393598PMC
November 2016

Challenges in the Management of Short Stature.

Authors:
Jesús Argente

Horm Res Paediatr 2016 10;85(1):2-10. Epub 2015 Dec 10.

Department of Pediatrics and Pediatric Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa, Universidad Autónoma de Madrid, and CIBER de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain.

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http://dx.doi.org/10.1159/000442350DOI Listing
October 2016

The role of astrocytes in the hypothalamic response and adaptation to metabolic signals.

Prog Neurobiol 2016 09 18;144:68-87. Epub 2016 Mar 18.

Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación la Princesa, CIBER de Obesidad Fisiopatología de la Obesidad y Nutrición (CIBEROBN). Instituto de Salud Carlos III, Madrid, Spain; Department of Pediatrics, Universidad Autónoma de Madrid, Madrid, Spain.

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http://dx.doi.org/10.1016/j.pneurobio.2016.03.001DOI Listing
September 2016

Nutritional and Pubertal Disorders.

Endocr Dev 2016 17;29:153-73. Epub 2015 Dec 17.

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http://dx.doi.org/10.1159/000438884DOI Listing
July 2016

[Skeletal dysplasias: New medical treatments].

An Pediatr (Barc) 2016 Jul 23;85(1):1-3. Epub 2016 Apr 23.

Servicio de Pediatría, Hospital Infantil Universitario Niño Jesús, Madrid, España; Servicio de Endocrinología, Hospital Infantil Universitario Niño Jesús, Madrid, España; Departamento de Pediatría, Universidad Autónoma de Madrid, Madrid, España; CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, España.

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http://dx.doi.org/10.1016/j.anpedi.2016.03.015DOI Listing
July 2016

[X-linked hypophosphatemic rickets due to mutations in PHEX: Clinical and evolutionary variability].

An Pediatr (Barc) 2016 Jul 21;85(1):41-3. Epub 2016 May 21.

Servicio de Endocrinología, Hospital Infantil Universitario Niño Jesús, Madrid, España; Departamento de Pediatría, Universidad Autónoma de Madrid, Madrid, España; CIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, España. Electronic address:

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http://dx.doi.org/10.1016/j.anpedi.2016.04.012DOI Listing
July 2016

Increased oxidative stress and apoptosis in the hypothalamus of diabetic male mice in the insulin receptor substrate-2 knockout model.

Dis Model Mech 2016 05 24;9(5):573-83. Epub 2016 Mar 24.

Department of Paediatrics, Universidad Autónoma de Madrid, Av. Menéndez Pelayo, 65, Madrid 28009, Spain Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Av. Menéndez Pelayo, 65, Madrid 28009, Spain Instituto de Investigación Sanitaria Princesa, IIS-IP, Madrid E-28006, Spain Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid E-28029, Spain

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http://dx.doi.org/10.1242/dmm.023515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892662PMC
May 2016

Age and sex dependent effects of early overnutrition on metabolic parameters and the role of neonatal androgens.

Biol Sex Differ 2016 18;7:26. Epub 2016 May 18.

Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa, Avenida Menéndez Pelayo 65, Madrid, 28009 Spain ; Centro de Investigación Biomédica en Red de la Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain.

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http://dx.doi.org/10.1186/s13293-016-0079-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870809PMC
May 2016

Mutations in pregnancy-associated plasma protein A2 cause short stature due to low IGF-I availability.

EMBO Mol Med 2016 04;8(4):363-74

Department of Pediatrics & Pediatric Endocrinology, Hospital Infantil Universitario Niño Jesús Instituto de Investigación La Princesa Universidad Autónoma de Madrid, Madrid, Spain Program of Pediatric Obesity, CIBEROBN Instituto de Salud Carlos III, Madrid, Spain

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http://dx.doi.org/10.15252/emmm.201506106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818753PMC
April 2016

Improvement in glycemia after glucose or insulin overload in leptin-infused rats is associated with insulin-related activation of hepatic glucose metabolism.

Nutr Metab (Lond) 2016 1;13:19. Epub 2016 Mar 1.

Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa, Avda. Menéndez Pelayo, 65, E-28009 Madrid, Spain ; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, E-28009 Spain.

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http://dx.doi.org/10.1186/s12986-016-0079-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774133PMC
March 2016

Ghrelin Regulates Glucose and Glutamate Transporters in Hypothalamic Astrocytes.

Sci Rep 2016 Mar 30;6:23673. Epub 2016 Mar 30.

Hospital Infantil Universitario Niño Jesús, Department of Endocrinology, Instituto de Investigación La Princesa, University Autónoma of Madrid and Centro de Investigación Biomédica en Red (CIBER) de la Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain.

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http://dx.doi.org/10.1038/srep23673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812252PMC
March 2016

Interaction between neonatal maternal deprivation and serum leptin levels on metabolism, pubertal development, and sexual behavior in male and female rats.

Biol Sex Differ 2016 11;7. Epub 2016 Jan 11.

Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación la Princesa, Avenida Menéndez Pelayo, 65, Madrid, 28009 Spain ; CIBEROBN, Instituto Carlos III Madrid, Madrid, Spain.

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http://dx.doi.org/10.1186/s13293-015-0054-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710050PMC
January 2016

Chronic central leptin infusion modulates the glycemia response to insulin administration in male rats through regulation of hepatic glucose metabolism.

Mol Cell Endocrinol 2015 Nov 18;415:157-72. Epub 2015 Aug 18.

Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa, Department of Pediatrics, Universidad Autónoma de Madrid, Madrid, E-28009, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, E-28009, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2015.08.014DOI Listing
November 2015

Blockage of the Neonatal Leptin Surge Affects the Gene Expression of Growth Factors, Glial Proteins, and Neuropeptides Involved in the Control of Metabolism and Reproduction in Peripubertal Male and Female Rats.

Endocrinology 2015 Jul 9;156(7):2571-81. Epub 2015 Apr 9.

Department of Physiology (Animal Physiology II) (V.M., A.B.L.-R., M.-P.V.), Faculty of Biology, Universidad Complutense, 28040 Madrid, Spain; Department of Endocrinology (F.D., J.A., J.A.C.), Hospital Infantil Universitario Niño Jesús, Department of Pediatrics, Universidad Autónoma de Madrid, Instituto de Investigación Sanitaria Princesa, 28009 Madrid, Spain; Centro de Investigación Biomédica en Red (CIBER) Fisiopatología de Obesidad y Nutrición (F.D., M.J.V., J.A., M.T.-S., J.A.C.), Instituto Carlos III, 28903 Madrid, Spain; Department of Cell Biology, Physiology, and Immunology (M.J.V., M.T.-S.), University of Córdoba and Instituto Maimónides de Investigación Biomédica, Hospital Universitario Reina Sofia, 14004 Córdoba, Spain; and The Robert H. Smith Faculty of Agriculture, Food and Environment (A.G.), The Hebrew University of Jerusalem, Rehovot, Israel 76100.

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http://dx.doi.org/10.1210/en.2014-1981DOI Listing
July 2015

A proteomic approach to obesity and type 2 diabetes.

J Cell Mol Med 2015 Jul 9;19(7):1455-70. Epub 2015 May 9.

Departments of Endocrinology and Pediatrics, Hospital Infantil Universitario Niño Jesús, Universidad Autónoma de Madrid, Madrid, Spain.

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http://dx.doi.org/10.1111/jcmm.12600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511345PMC
July 2015

Pathology or normal variant: what constitutes a delay in puberty?

Horm Res Paediatr 2014 7;82(4):213-21. Epub 2014 Jul 7.

Department of Pediatrics and Pediatric Endocrinology, Hospital Infantil Universitario Niño Jesús, Universidad Autónoma de Madrid, Madrid, Spain.

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https://www.karger.com/Article/FullText/362600
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http://dx.doi.org/10.1159/000362600DOI Listing
June 2015

Need to optimize nutritional support in very-low-birth-weight infants.

Neonatology 2015 14;107(1):79-80. Epub 2014 Nov 14.

Department of Neonatology, Hospital Universitario La Paz, Madrid, Spain.

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http://dx.doi.org/10.1159/000367911DOI Listing
May 2015

Increased prepubertal body weight enhances leptin sensitivity in proopiomelanocortin and neuropeptide y neurons before puberty onset in female rats.

Endocrinology 2015 Apr 9;156(4):1272-82. Epub 2015 Jan 9.

Department of Endocrinology (D.C.-G., E.F.-M., P.A.-A., V.B., J.A.C., J.A.), Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa (D.C.-G., E.F.-M., P.A.-A., V.B., J.A.C., J.A.), 3Department of Pediatrics (D.C.-G., E.F.-M., P.A.-A., J.A.), Universidad Autónoma de Madrid, E-28049 Madrid, Spain; Centros de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición (D.C.-G., E.F.-M., M.A.S.-G., P.A.-A., M.T.-S., V.B., J.A.C., J.A.), Instituto de Salud Carlos III, E-28009 Madrid, Spain; and Department of Cell Biology, Physiology and Immunology (M.A.S.-G., M.T.-S.), University of Córdoba, Instituto Maimónides de Investigacion Biomédicas de Córdoba/ Hospital Universitario Reina Sofia, 14004 Córdoba, Spain.

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http://dx.doi.org/10.1210/en.2014-1759DOI Listing
April 2015

Role of non-neuronal cells in body weight and appetite control.

Front Endocrinol (Lausanne) 2015 26;6:42. Epub 2015 Mar 26.

Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa , Madrid , Spain ; Fisiopatología de la Obesidad y Nutrición (CIBERobn), Centros de Investigación Biomédica en Red, Instituto de Salud Carlos III , Madrid , Spain.

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http://dx.doi.org/10.3389/fendo.2015.00042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374626PMC
April 2015

Growth in preterm infants until 36 weeks' postmenstrual age is close to target recommendations.

Neonatology 2014 23;106(1):30-6. Epub 2014 Apr 23.

Department of Neonatology, Hospital Universitario La Paz, Madrid, Spain.

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http://dx.doi.org/10.1159/000358479DOI Listing
March 2015

The absence of GH signaling affects the susceptibility to high-fat diet-induced hypothalamic inflammation in male mice.

Endocrinology 2014 Dec 19;155(12):4856-67. Epub 2014 Sep 19.

Department of Pediatrics (E.B., A.M.R.-L., J.A.C., L.M.F., J.A.), Universidad Autónoma de Madrid; Department of Endocrinology, Hospital Infantil Universitario Niño Jesús 28009, Madrid, Spain; Instituto de Investigación Sanitaria Princesa; and Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, 28009 Madrid, Spain; and The Edison Biotechnology Institute (E.G.S., J.H., E.O.L., J.J.K.) and Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio 45701.

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http://dx.doi.org/10.1210/en.2014-1367DOI Listing
December 2014

Underdiagnosed Beckwith-Wiedemann syndrome among early onset obese children.

Arch Dis Child 2014 Oct 1;99(10):965-7. Epub 2014 Aug 1.

Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa, Madrid, Spain Department of Pediatrics, Universidad Autónoma de Madrid, Madrid, Spain CIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, Spain.

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http://dx.doi.org/10.1136/archdischild-2014-307097DOI Listing
October 2014

The opposing effects of ghrelin on hypothalamic and systemic inflammatory processes are modulated by its acylation status and food intake in male rats.

Endocrinology 2014 Aug 21;155(8):2868-80. Epub 2014 May 21.

Hospital Infantil Universitario Niño Jesús, Department of Endocrinology, Instituto de Investigación La Princesa, Universidad Autónoma de Madrid and Centro de Investigación Biomédica en Red (CIBER) de la Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, 28009 Madrid, Spain.

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http://dx.doi.org/10.1210/en.2014-1074DOI Listing
August 2014

Leptin signaling in astrocytes regulates hypothalamic neuronal circuits and feeding.

Nat Neurosci 2014 Jul 1;17(7):908-10. Epub 2014 Jun 1.

1] Program in Integrative Cell Signaling and Neurobiology of Metabolism, Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut, USA. [2] Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut, USA. [3] Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1038/nn.3725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113214PMC
July 2014

Proteomic analysis allows for early detection of potential markers of metabolic impairment in very young obese children.

Int J Pediatr Endocrinol 2014 10;2014(1). Epub 2014 Jun 10.

Edison Biotechnology Institute, Ohio University, Konneker Research Laboratories, 1 Water Tower Drive, The Ridges, 45701 Athens, Ohio, USA ; Molecular and Cellular Biology Program, Ohio University, Athens, Ohio, USA ; Department of Biomedical Sciences, College of Osteopathic Medicine, Ohio University, Athens, Ohio, USA.

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http://dx.doi.org/10.1186/1687-9856-2014-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063220PMC
June 2014

The "glacier crevice" sign, from image to diagnosis.

J Pediatr 2014 May 22;164(5):1237-1237.e1. Epub 2014 Feb 22.

Department of Pediatrics and Endocrinology, Hospital Infantil Universitario Niño Jesús, Universidad Autónoma de Madrid and CIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, Spain.

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http://dx.doi.org/10.1016/j.jpeds.2014.01.026DOI Listing
May 2014

Principles and pitfalls in the differential diagnosis and management of childhood obesities.

Adv Nutr 2014 May 14;5(3):299S-305S. Epub 2014 May 14.

Department of Pediatrics and Pediatric Endocrinology, Hospital Infantil Universitario Niño Jesús; Instituto de Investigación La Princesa; Department of Pediatrics, Universidad Autónoma de Madrid; CIBER Fisiopatología Obesidad y Nutrición; Instituto de Salud Carlos III, Madrid, Spain

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http://dx.doi.org/10.3945/an.113.004853DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013186PMC
May 2014

Defective minor spliceosome mRNA processing results in isolated familial growth hormone deficiency.

EMBO Mol Med 2014 03 30;6(3):299-306. Epub 2014 Jan 30.

Departments of Endocrinology and Pediatrics, Hospital Infantil Universitario Niño Jesús Universidad Autónoma de Madrid, Madrid, Spain.

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http://dx.doi.org/10.1002/emmm.201303573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958305PMC
March 2014

Adipokines in childhood obesity.

Vitam Horm 2013 ;91:107-42

Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa, Madrid, Spain.

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http://dx.doi.org/10.1016/B978-0-12-407766-9.00006-7DOI Listing
December 2013

Differential effects of GH and GH-releasing peptide-6 on astrocytes.

J Endocrinol 2013 Sep 29;218(3):263-74. Epub 2013 Jul 29.

Department of Pediatrics, Universidad Autónoma de Madrid, Madrid, Spain.

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http://dx.doi.org/10.1530/JOE-13-0053DOI Listing
September 2013

Uncovering novel roles of nonneuronal cells in body weight homeostasis and obesity.

Endocrinology 2013 Sep 24;154(9):3001-7. Epub 2013 Jun 24.

Hospital Infantil Universitario Niño Jesús, Department of Endocrinology, Instituto de Investigación La Princesa, 28009 Madrid, Spain.

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http://dx.doi.org/10.1210/en.2013-1303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749483PMC
September 2013

Hypothalamic inflammation without astrogliosis in response to high sucrose intake is modulated by neonatal nutrition in male rats.

Endocrinology 2013 Jul 13;154(7):2318-30. Epub 2013 May 13.

Hospital Infantil Universitario Niño Jesús, Department of Endocrinology, Instituto de Investigación La Princesa, 28009 Madrid, Spain.

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http://dx.doi.org/10.1210/en.2012-2196DOI Listing
July 2013

Sex differences in adipose tissue: It is not only a question of quantity and distribution.

Adipocyte 2013 Jul 1;2(3):128-34. Epub 2013 Aug 1.

Department of Pediatric Endocrinology; Hospital Infantil Universitario Niño Jesús; Instituto de Investigación La Princesa; Madrid, Spain ; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBERobn); Instituto de Salud Carlos III; Madrid, Spain.

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http://dx.doi.org/10.4161/adip.24075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756100PMC
July 2013

Association between umbilical cord leptin and weight gain according to feeding type in the early postnatal period, a brief report.

Rev Invest Clin 2012 Nov-Dec;64(6 Pt 2):615-9

Departamento de Pediatría, Hospital Universitario Dr. José E. González, Universidad Autónoma de Nuevo León, Monterrey, NL.

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June 2013

Maternal deprivation exacerbates the response to a high fat diet in a sexually dimorphic manner.

PLoS One 2012 7;7(11):e48915. Epub 2012 Nov 7.

Department of Physiology (Animal Physiology II), Faculty of Biology, Universidad Complutense, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0048915PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492147PMC
May 2013