Publications by authors named "Jessie M English"

18Publications

Combination Therapy with NHS-muIL12 and Avelumab (anti-PD-L1) Enhances Antitumor Efficacy in Preclinical Cancer Models.

Clin Cancer Res 2017 Oct 5;23(19):5869-5880. Epub 2017 Jul 5.

Immuno-Oncology Translational Innovation Platform, EMD Serono Research and Development Institute, Billerica, Massachusetts.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-0483DOI Listing
October 2017

Enhanced selectivity profile of pyrazole-urea based DFG-out p38alpha inhibitors.

Bioorg Med Chem Lett 2010 Aug 17;20(16):4885-91. Epub 2010 Jun 17.

Department of Chemistry, Cambridge South Laboratories, Pfizer Inc., 620 Memorial Drive, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.bmcl.2010.06.073DOI Listing
August 2010

Function of activation loop tyrosine phosphorylation in the mechanism of c-Kit auto-activation and its implication in sunitinib resistance.

J Biochem 2010 Apr 10;147(4):601-9. Epub 2010 Feb 10.

Pfizer Research Technology Center, 620 Memorial Drive, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1093/jb/mvq015DOI Listing
April 2010

WNK1 is a novel regulator of Munc18c-syntaxin 4 complex formation in soluble NSF attachment protein receptor (SNARE)-mediated vesicle exocytosis.

J Biol Chem 2007 Nov 11;282(45):32613-22. Epub 2007 Sep 11.

Department of Biochemistry and Molecular Biology, Center for Diabetes Research, Indiana University School of Medicine, 635 Barnhill Drive, Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.1074/jbc.M706591200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423411PMC
November 2007

Mechanisms of drug inhibition of signalling molecules.

Nature 2006 May;441(7092):457-62

Pfizer Global Research and Development, Michigan Laboratories, 2800 Plymouth Road, Ann Arbor, Michigan 48105, USA.

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http://dx.doi.org/10.1038/nature04874DOI Listing
May 2006

WNK1 activates SGK1 to regulate the epithelial sodium channel.

Proc Natl Acad Sci U S A 2005 Jul 8;102(29):10315-20. Epub 2005 Jul 8.

Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9041, USA.

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http://dx.doi.org/10.1073/pnas.0504422102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1177404PMC
July 2005

Analysis of the ERK1,2 transcriptome in mammary epithelial cells.

Biochem J 2004 Aug;381(Pt 3):635-44

Biological Research-Oncology, Schering-Plough Research Institute, Kenilworth, NJ 07033, USA.

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http://dx.doi.org/10.1042/BJ20031688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1133872PMC
August 2004

Inhibitors of farnesyl protein transferase and MEK1,2 induce apoptosis in fibroblasts transformed with farnesylated but not geranylgeranylated H-Ras.

Exp Cell Res 2002 Feb;273(2):138-46

Biotechnology Development, Schering-Plough Research Institute, Union, New Jersey 07083, USA.

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http://dx.doi.org/10.1006/excr.2001.5440DOI Listing
February 2002

Pharmacological inhibitors of MAPK pathways.

Trends Pharmacol Sci 2002 Jan;23(1):40-5

(1) Dept of Biological Research-Oncology, Schering-Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033. (2) Dept of Pharmacology, U.T.Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-9041.

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http://dx.doi.org/10.1016/s0165-6147(00)01865-4DOI Listing
January 2002