Jessica Zucman-Rossi

Jessica Zucman-Rossi

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Jessica Zucman-Rossi

Publications by authors named "Jessica Zucman-Rossi"

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Corrigendum to: "BAP1 mutations define a homogeneous subgroup of hepatocellular carcinoma with fibrolamellar-like features and activated PKA" [J Hepatol (2020) 1-13].

J Hepatol 2020 Jul 29;73(1):225-226. Epub 2020 Apr 29.

Centre de Recherche des Cordeliers, Sorbonne Université, Inserm, Université de Paris, F-75006 Paris, France; Functional Genomics of Solid Tumors laboratory, équipe labellisée Ligue Nationale contre le Cancer, Labex OncoImmunology, F-75006, Paris, France; Hôpital Européen Georges Pompidou, APHP, F-75015 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2020.04.004DOI Listing
July 2020

New insights in the management of Hepatocellular Adenoma.

Liver Int 2020 Jul 11;40(7):1529-1537. Epub 2020 Jun 11.

Department of Surgery, Erasmus MC University Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1111/liv.14547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383747PMC
July 2020

abnormal transcripts result from read-through in liver tumours with high ß-catenin activation and mutations.

Gut 2020 Jun 1;69(6):1152-1153. Epub 2019 Jun 1.

Centre de Recherche des Cordeliers, Inserm, Paris, France.

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http://dx.doi.org/10.1136/gutjnl-2019-319089DOI Listing
June 2020

BAP1 mutations define a homogeneous subgroup of hepatocellular carcinoma with fibrolamellar-like features and activated PKA.

J Hepatol 2020 May 18;72(5):924-936. Epub 2019 Dec 18.

Centre de Recherche des Cordeliers, Sorbonne Université, Inserm, Université de Paris, F-75006 Paris, France; Functional Genomics of Solid Tumors laboratory, équipe labellisée Ligue Nationale contre le Cancer, Labex OncoImmunology, F-75006, Paris, France; Hôpital Européen Georges Pompidou, APHP, F-75015 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2019.12.006DOI Listing
May 2020

Long-term Evolution of Hepatocellular Adenomas at MRI Follow-up.

Radiology 2020 05 17;295(2):361-372. Epub 2020 Mar 17.

From the University of Paris, Paris, France (F.V., M.R., F.C., O.S., D.V., V.P., V.V.); Departments of Radiology (M.R., M.D.B., V.V.), Liver Transplantation and Hepatobiliary Surgery (F.C., S.D., O.S.), and Hepatology (D.V.), and Pathology Department (V.P.), University Hospitals Paris Nord Val de Seine, Beaujon, Clichy, Hauts-de-Seine, France; INSERM, UMR 1149, Paris, France (M.R., F.C., O.S., D.V., M.D.B., V.P., V.V.); Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC (K.R.C.); INSERM, UMR 1162, Génomique Fonctionnelle des Tumeurs Solides, Université Paris Descartes, Université Paris Diderot, Université Paris 13, Labex Immuno-Oncology, Paris, France (J.Z.), Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Palermo, Italy (F.V.).

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http://dx.doi.org/10.1148/radiol.2020191790DOI Listing
May 2020

Genetics of HCC: Novel approaches to explore molecular diversity.

Hepatology 2020 May 28. Epub 2020 May 28.

Centre de Recherche des Cordeliers, INSERM, Sorbonne Université, Université de Paris, Université Paris 13, Functional Genomics of Solid Tumors laboratory, F-75006, Paris, France.

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http://dx.doi.org/10.1002/hep.31394DOI Listing
May 2020

Polyploidy spectrum: a new marker in HCC classification.

Gut 2020 02 12;69(2):355-364. Epub 2019 Apr 12.

Team Proliferation Stress and Liver Physiopathology, Genome and Cancer, Centre de Recherche des Cordeliers, INSERM, Sorbonne Université, USPC, Université Paris Descartes, Université Paris Diderot, Paris, France.

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http://gut.bmj.com/lookup/doi/10.1136/gutjnl-2018-318021
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http://dx.doi.org/10.1136/gutjnl-2018-318021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984053PMC
February 2020

Natural history of liver adenomatosis: A long-term observational study.

J Hepatol 2019 12 13;71(6):1184-1192. Epub 2019 Aug 13.

Department of Hepatology and Gastroenterology, University Hospital of Tours, Tours, France.

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http://dx.doi.org/10.1016/j.jhep.2019.08.004DOI Listing
December 2019

Journal of Hepatology: The Home of Liver Research, 2015-2019.

J Hepatol 2019 12;71(6):1065-1069

Journal of Hepatology, European Association from the Study of the Liver, Geneva, Switzerland.

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http://dx.doi.org/10.1016/j.jhep.2019.09.017DOI Listing
December 2019

Clear-cell Renal Cell Carcinoma: Molecular Characterization of IMDC Risk Groups and Sarcomatoid Tumors.

Clin Genitourin Cancer 2019 10 25;17(5):e981-e994. Epub 2019 May 25.

Department of General Medical Oncology, University Hospitals Leuven, Leuven, Belgium; Laboratory of Experimental Oncology, Department of Oncology, KU Leuven, Leuven, Belgium; Inserm, UMR-1162, Génomique fonctionnelle des tumeurs solides, IUH, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.clgc.2019.05.009DOI Listing
October 2019

Immunogenomics of Metastatic Clear-Cell Renal Cell Carcinoma: Remarkable Response to Nivolumab in a Patient With a Pathogenic Germ Line BRCA1 Mutation.

Clin Genitourin Cancer 2019 10 11;17(5):e909-e912. Epub 2019 Jul 11.

Department of General Medical Oncology, University Hospitals Leuven, Leuven Cancer Institute, KU Leuven, Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.clgc.2019.06.013DOI Listing
October 2019

Analysis of Liver Cancer Cell Lines Identifies Agents With Likely Efficacy Against Hepatocellular Carcinoma and Markers of Response.

Gastroenterology 2019 09 4;157(3):760-776. Epub 2019 May 4.

Centre de Recherche des Cordeliers, Sorbonne Université, Inserm, UMRS-1138, F-75006 Paris, France; Functional Genomics of Solid Tumors, USPC, Université Paris Descartes, Université Paris Diderot, Université Paris 13, Labex Immuno-Oncology, équipe labellisée Ligue Contre le Cancer, F-75000 Paris, France. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.05.001DOI Listing
September 2019

Hepatocellular Carcinomas With Mutational Activation of Beta-Catenin Require Choline and Can Be Detected by Positron Emission Tomography.

Gastroenterology 2019 09 10;157(3):807-822. Epub 2019 Jun 10.

Institut Cochin, Institut National de la Santé et de la Recherche Médicale U1016, Centre National de la Recherche Scientifique, Unité Mixte De Recherché 8104, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France; Centre de Recherche des Cordeliers, Institut National de la Santé et de la Recherche Médicale Unité Mixte De Recherche 1138, Equipe Labellisée Ligue Contre le Cancer, Paris, France. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.05.069DOI Listing
September 2019

Molecular and histological correlations in liver cancer.

J Hepatol 2019 09 10;71(3):616-630. Epub 2019 Jun 10.

INSERM UMR-1162, Génomique Fonctionnelle des Tumeurs Solides, 75010 Paris, France; Université Paris Descartes, Université Paris Diderot, Université Paris 13, F-75010, France; Assistance Publique-Hôpitaux de Paris, Service d'Oncologie Médicale, Hôpital Européen Georges Pompidou, Paris, France.

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http://dx.doi.org/10.1016/j.jhep.2019.06.001DOI Listing
September 2019

The role of telomeres and telomerase in cirrhosis and liver cancer.

Nat Rev Gastroenterol Hepatol 2019 09 28;16(9):544-558. Epub 2019 Jun 28.

Centre de Recherche des Cordeliers, Sorbonne Université, Inserm, USPC, Université Paris Descartes, Université Paris Diderot, Université Paris 13, Functional Genomics of Solid Tumors laboratory, F-75006, Paris, France.

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http://dx.doi.org/10.1038/s41575-019-0165-3DOI Listing
September 2019

Inhibiting Glutamine-Dependent mTORC1 Activation Ameliorates Liver Cancers Driven by β-Catenin Mutations.

Cell Metab 2019 05 31;29(5):1135-1150.e6. Epub 2019 Jan 31.

Division of Experimental Pathology, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Pittsburgh Liver Research Center, University of Pittsburgh Medical Center and University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2019.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506359PMC
May 2019

JHEP Reports: A new EASL open access journal.

JHEP Rep 2019 May 25;1(1). Epub 2019 Mar 25.

Centre de recherche des Cordeliers, Inserm U1138, Université Paris Descartes, Sorbonne Université, Université Paris Diderot, 15 rue de l'école de médecine, 75006 Paris, France.

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http://dx.doi.org/10.1016/j.jhepr.2019.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001529PMC
May 2019

Fibroblast Growth Factor Receptor-2 Polymorphism rs2981582 is Correlated With Progression-free Survival and Overall Survival in Patients With Metastatic Clear-cell Renal Cell Carcinoma Treated With Sunitinib.

Clin Genitourin Cancer 2019 04 16;17(2):e235-e246. Epub 2018 Nov 16.

Department of General Medical Oncology, University Hospitals Leuven, Leuven Cancer Institute, KU Leuven, Leuven, Belgium; Inserm UMR1162 Génomique Fonctionnelle des Tumeurs Solides, Université Paris-5 René Descartes, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.clgc.2018.11.002DOI Listing
April 2019

Intra-tumoral tertiary lymphoid structures are associated with a low risk of early recurrence of hepatocellular carcinoma.

J Hepatol 2019 01 11;70(1):58-65. Epub 2018 Sep 11.

INSERM UMR_S1138, Centre de Recherche des Cordeliers, Equipe cancer et immunité anti-tumorale, 15 rue de l'Ecole de Médecine, F75006 Paris, France; Université Paris Descartes Paris 5, Sorbonne Paris Cite, UPMC Université Paris 6, F-75006 Paris, France.

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http://dx.doi.org/10.1016/j.jhep.2018.09.003DOI Listing
January 2019

Genomic Medicine and Implications for Hepatocellular Carcinoma Prevention and Therapy.

Gastroenterology 2019 01 4;156(2):492-509. Epub 2018 Nov 4.

Institut National de la Santé et de la Recherche Médicale, Unité Mixte De Recherche 1162, Génomique Fonctionnelle des Tumeurs Solides, Université Paris Descartes, Université Paris Diderot, Université Paris 13, Labex Immuno-Oncology, Paris, France; Hôpital Europeen Georges Pompidou, Assistance Publique-Hôpitaux de Paris, Paris, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085183521
Publisher Site
http://dx.doi.org/10.1053/j.gastro.2018.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340723PMC
January 2019

Assessment of signaling pathway inhibitors and identification of predictive biomarkers in malignant pleural mesothelioma.

Lung Cancer 2018 12 16;126:15-24. Epub 2018 Oct 16.

Inserm, UMR-1162, Génomique fonctionnelle des tumeurs solides, F-75010, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Labex Immuno-oncology, F-75000, Paris, France; Université Paris Diderot, Sorbonne Paris Cité, Institut Universitaire d'Hématologie, Paris, F-75010, France; Université Paris 13, Sorbonne Paris Cité, F-93206, Saint-Denis, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01695002183059
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http://dx.doi.org/10.1016/j.lungcan.2018.10.015DOI Listing
December 2018

Dietary exacerbation of metabolic stress leads to accelerated hepatic carcinogenesis in glycogen storage disease type Ia.

J Hepatol 2018 Nov 5;69(5):1074-1087. Epub 2018 Sep 5.

Institut National de la Santé et de la Recherche Médicale, U1213, Lyon F-69008, France; Université de Lyon, Lyon F-69008 France; Université Lyon I, Villeurbanne F-69622 France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01688278183227
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http://dx.doi.org/10.1016/j.jhep.2018.07.017DOI Listing
November 2018

Molecular Subtypes of Clear-cell Renal Cell Carcinoma are Prognostic for Outcome After Complete Metastasectomy.

Eur Urol 2018 10 17;74(4):474-480. Epub 2018 Feb 17.

Laboratory of Experimental Oncology, Department of Oncology, KU Leuven, Leuven, Belgium; Inserm, UMR-1162, Génomique Fonctionnelle des Tumeurs Solides, IUH, Paris, France; Department of General Medical Oncology, University Hospitals Leuven, Leuven Cancer Institute, Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2018.01.042DOI Listing
October 2018

Palimpsest: an R package for studying mutational and structural variant signatures along clonal evolution in cancer.

Bioinformatics 2018 10;34(19):3380-3381

INSERM, UMR-1162, Génomique Fonctionnelle des Tumeurs Solides, Equipe Labellisée Ligue Contre le Cancer, Institut Universitaire d'Hématologie; Faculté de Médecine, Université Paris Descartes, Labex Immuno-Oncology, Sorbonne Paris Cité; Unité de Formation et de Recherche Santé, Médecine, Biologie Humaine, Université Paris 13, Sorbonne Paris Cité, Bobigny, France; Université Paris Diderot, Paris, France.

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http://dx.doi.org/10.1093/bioinformatics/bty388DOI Listing
October 2018

Argininosuccinate synthase 1 and periportal gene expression in sonic hedgehog hepatocellular adenomas.

Hepatology 2018 09 6;68(3):964-976. Epub 2018 Jun 6.

Inserm UMR-1162, Génomique fonctionnelle des Tumeurs solides, Université Paris Descartes, Université Paris Diderot, Université Paris 13, Labex Immuno-Oncology, Paris, France.

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http://dx.doi.org/10.1002/hep.29884DOI Listing
September 2018

From the Editor's desk....: September 2018.

J Hepatol 2018 Sep 15;69(3):559-561. Epub 2018 Aug 15.

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http://dx.doi.org/10.1016/j.jhep.2018.06.006DOI Listing
September 2018

Polymorphisms in the Von Hippel-Lindau Gene Are Associated With Overall Survival in Metastatic Clear-Cell Renal-Cell Carcinoma Patients Treated With VEGFR Tyrosine Kinase Inhibitors.

Clin Genitourin Cancer 2018 08 5;16(4):266-273. Epub 2018 Feb 5.

Laboratory of Experimental Oncology, Department of Oncology, University of Leuven, Leuven, Belgium; Department of General Medical Oncology, University Hospitals Leuven, Leuven Cancer Institute, Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.clgc.2018.01.013DOI Listing
August 2018

Molecular Subtypes of Clear Cell Renal Cell Carcinoma Are Associated With Outcome During Pazopanib Therapy in the Metastatic Setting.

Clin Genitourin Cancer 2018 06 7;16(3):e605-e612. Epub 2017 Nov 7.

Laboratory of Experimental Oncology, Department of Oncology, University of Leuven, Leuven, Belgium; Department of General Medical Oncology, University Hospitals Leuven, Leuven Cancer Institute, Leuven, Belgium; Inserm, UMR-1162, Génomique fonctionnelle des tumeurs solides, Institut Universitaire Hématologie, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.clgc.2017.10.017DOI Listing
June 2018

AXIN deficiency in human and mouse hepatocytes induces hepatocellular carcinoma in the absence of β-catenin activation.

J Hepatol 2018 06 7;68(6):1203-1213. Epub 2018 Mar 7.

INSERM, U1016, Institut Cochin, F-75014 Paris, France; CNRS, UMR8104, F-75014 Paris, France; Université Paris Descartes, F-75014 Paris, France; Equipe labellisée LNCC, France; Centre de Recherche sur l'Inflammation-Inserm UMR 1149-Université Paris Diderot, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2017.12.018DOI Listing
June 2018

Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling.

Cancer Cell 2018 06;33(6):1061-1077.e6

Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, University of California San Diego, School of Medicine, 9500 Gilman Drive, San Diego, CA 92093, USA; Department of Pathology, University of California San Diego, School of Medicine, 9500 Gilman Drive, San Diego, CA 92093, USA; Moores Cancer Center, University of California San Diego, School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093-0723, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005359PMC
June 2018

The clinical implications of G1-G6 transcriptomic signature and 5-gene score in Korean patients with hepatocellular carcinoma.

BMC Cancer 2018 May 18;18(1):571. Epub 2018 May 18.

Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, 88, OLYMPIC-RO 43-GIL, SONGPA-GU, SEOUL, 138-736, South Korea.

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http://dx.doi.org/10.1186/s12885-018-4192-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960090PMC
May 2018

Focal β-catenin mutation identified on formalin-fixed and paraffin-embedded inflammatory hepatocellular adenomas.

Histopathology 2017 Dec 6;71(6):989-993. Epub 2017 Oct 6.

Service de Pathologie, Hôpital Pellegrin, CHU Bordeaux, Bordeaux, France.

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http://dx.doi.org/10.1111/his.13283DOI Listing
December 2017

Reply.

Hepatology 2017 12 6;66(6):2093-2094. Epub 2017 Nov 6.

Inserm UMR-1162 "Functional Genomics of Solid Tumors" Equipe labellisée Ligue Contre le Cancer, Paris, France.

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http://dx.doi.org/10.1002/hep.29563DOI Listing
December 2017

Molecular classification of hepatocellular adenoma in clinical practice.

J Hepatol 2017 11 19;67(5):1074-1083. Epub 2017 Jul 19.

Unité Mixte de Recherche 1162, Génomique fonctionnelle des tumeurs solides, Institut National de la Santé et de la Recherche Médicale, Paris, France; Université Paris Descartes, Labex Immuno-Oncology, Sorbonne Paris Cité, Faculté de Médecine, Paris, France; Assistance Publique-Hôpitaux de Paris, Hopital Europeen Georges Pompidou, F-75015 Paris, France.

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http://dx.doi.org/10.1016/j.jhep.2017.07.009DOI Listing
November 2017

Note of caution: Contaminations of hepatocellular cell lines.

J Hepatol 2017 11 12;67(5):896-897. Epub 2017 Aug 12.

State Key Laboratory of Cell Biology, Excellence Center for Molecular Cell Sciences, Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai 200031, China.

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https://linkinghub.elsevier.com/retrieve/pii/S01688278173220
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http://dx.doi.org/10.1016/j.jhep.2017.08.002DOI Listing
November 2017

Histological subtypes of hepatocellular carcinoma are related to gene mutations and molecular tumour classification.

J Hepatol 2017 10 19;67(4):727-738. Epub 2017 May 19.

Inserm, UMR-1162, Functional Genomics of Solid Tumors, Equipe Labellisée Ligue Contre le Cancer, Université Paris Descartes, Université Paris Diderot, Université Paris 13, F-75010, France; Assistance Publique-Hôpitaux de Paris, Department of Oncology, Hôpital Européen Georges Pompidou, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2017.05.014DOI Listing
October 2017

Proliferation Markers Are Associated with MET Expression in Hepatocellular Carcinoma and Predict Tivantinib Sensitivity .

Clin Cancer Res 2017 Aug 28;23(15):4364-4375. Epub 2017 Feb 28.

Inserm UMR-1162, Génomique Fonctionnelle des Tumeurs Solides, Université Paris Descartes, Université Paris Diderot, Université Paris 13, Labex Immuno-Oncology, Paris, France.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-3118DOI Listing
August 2017

Co-occurring Mutations of Tumor Suppressor Genes, and , in Malignant Pleural Mesothelioma.

Clin Cancer Res 2017 Jun 21;23(12):3191-3202. Epub 2016 Dec 21.

Génomique Fonctionnelle des Tumeurs Solides, INSERM, UMR-1162, Equipe labellisée Ligue Contre le Cancer, Paris, France.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-1971DOI Listing
June 2017

Mutational signature analysis identifies MUTYH deficiency in colorectal cancers and adrenocortical carcinomas.

J Pathol 2017 05 29;242(1):10-15. Epub 2017 Mar 29.

INSERM UMR-S1147, Personalized Medicine, Pharmacogenomics, Therapeutic Optimization, Université Paris Descartes, Paris, France.

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http://dx.doi.org/10.1002/path.4880DOI Listing
May 2017

Malignant transformation of a β-catenin inflammatory adenoma due to an S45 β-catenin-activating mutation present 12 years before.

Hum Pathol 2017 Apr 28;62:122-125. Epub 2016 Oct 28.

Université Bordeaux, Inserm U1053, 33076 Bordeaux Cedex, France. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2016.10.004DOI Listing
April 2017

Germline and somatic DICER1 mutations in familial and sporadic liver tumors.

J Hepatol 2017 04 22;66(4):734-742. Epub 2016 Dec 22.

INSERM, Unité Mixte de Recherche (UMR) 1162, Génomique Fonctionnelle des Tumeurs Solides, Equipe Labellisée Ligue contre le Cancer, Paris, France; Université Paris Descartes, Labex Immuno-Oncology, Sorbonne Paris Cité, Paris, France; Université Paris 13, Sorbonne Paris Cité, Unité de Formation et de Recherche (UFR) Santé, Médecine, Biologie Humaine (SMBH), Bobigny, France; Université Paris Diderot, Institut Universitaire d'Hématologie, Paris, France; AP-HP, Hôpital Européen Georges Pompidou, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2016.12.010DOI Listing
April 2017

Molecular Classification of Hepatocellular Adenoma Associates With Risk Factors, Bleeding, and Malignant Transformation.

Gastroenterology 2017 03 7;152(4):880-894.e6. Epub 2016 Dec 7.

Unité Mixte de Recherche 1162, Génomique Fonctionnelle des Tumeurs Solides, Institut National de la Santé et de la Recherche Médicale, Université Paris Descartes, Université Paris Diderot, Paris, France; Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Département d'Oncologie, Paris, France. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2016.11.042DOI Listing
March 2017

RIPK1 Suppresses a TRAF2-Dependent Pathway to Liver Cancer.

Cancer Cell 2017 01 22;31(1):94-109. Epub 2016 Dec 22.

Department of Medicine III, RWTH Aachen University, 52074 Aachen, Germany; Division of Gastroenterology, Hepatology and Hepatobiliary Oncology, RWTH Aachen University, 52074 Aachen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.11.009DOI Listing
January 2017

Genotype-phenotype correlation of CTNNB1 mutations reveals different ß-catenin activity associated with liver tumor progression.

Hepatology 2016 12 11;64(6):2047-2061. Epub 2016 Jun 11.

Inserm, UMR-1162, Functional Genomics of Solid Tumors, Equipe labellisée Ligue Contre le Cancer, Paris, France.

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http://dx.doi.org/10.1002/hep.28638DOI Listing
December 2016

TGF-β1 promotes linear invadosome formation in hepatocellular carcinoma cells, through DDR1 up-regulation and collagen I cross-linking.

Eur J Cell Biol 2016 Nov 4;95(11):503-512. Epub 2016 Oct 4.

INSERM, U1053 Bordeaux Research In Translational Oncology, BaRITOn, F-33000 Bordeaux, France; Univ. Bordeaux, U1053 Bordeaux Research In Translational Oncology, BaRITOn, F-33000 Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejcb.2016.09.003DOI Listing
November 2016

The liver-specific microRNA-122*, the complementary strand of microRNA-122, acts as a tumor suppressor by modulating the p53/mouse double minute 2 homolog circuitry.

Hepatology 2016 11 25;64(5):1623-1636. Epub 2016 Jul 25.

The Goldyne Savad Institute of Gene and Cell Therapy, Hadassah Hebrew University Hospital, Ein Karem, Jerusalem, Israel.

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http://dx.doi.org/10.1002/hep.28679DOI Listing
November 2016

The transcriptomic G1-G6 signature of hepatocellular carcinoma in an Asian population: Association of G3 with microvascular invasion.

Medicine (Baltimore) 2016 Nov;95(47):e5263

aCentre for Quantitative Medicine, Duke-NUS Graduate Medical School, Singapore, Singapore bINSERM, UMR-1162, Génomique Fonctionnelle des Tumeurs Solides, IUH cUniversité Paris Descartes, Labex Immuno-oncology, Sorbonne Paris Cité, Faculté de Médecine, Paris, France dDepartment of Pathology, Singapore General Hospital, Singapore eDepartment of Surgical Oncology, National Cancer Centre fOffice of Clinical Sciences, Duke-NUS Medical School, Singapore gDepartment of HPB and Transplant Surgery, Singapore General Hospital, Singapore, Singapore.

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http://dx.doi.org/10.1097/MD.0000000000005263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134855PMC
November 2016

Immune Contexture, Immunoscore, and Malignant Cell Molecular Subgroups for Prognostic and Theranostic Classifications of Cancers.

Adv Immunol 2016 29;130:95-190. Epub 2016 Jan 29.

INSERM UMR_S 1138, Cancer, Immune Control and Escape, Cordeliers Research Centre, Paris, France; Université Paris-Descartes, Sorbonne Paris Cité, UMR_S 1338, Cordeliers Research Centre, Paris, France; Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1138, Cordeliers Research Centre, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/bs.ai.2015.12.002DOI Listing
October 2016

Keratin 23 is a stress-inducible marker of mouse and human ductular reaction in liver disease.

J Hepatol 2016 09 2;65(3):552-9. Epub 2016 May 2.

Department of Internal Medicine III, RWTH University Hospital Aachen, Germany; Interdisciplinary Center for Clinical Research (IZKF), RWTH University Hospital Aachen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2016.04.024DOI Listing
September 2016

PNPLA3 gene in liver diseases.

J Hepatol 2016 08 30;65(2):399-412. Epub 2016 Mar 30.

Inserm, UMR-1162, Génomique Fonctionnelle des Tumeurs Solides, Equipe Labellisée Ligue Contre le Cancer, Institut Universitaire d'Hématologie, Paris, France; Université Paris 13, Sorbonne Paris Cité, Unité de Formation et de Recherche Santé, Médecine, Biologie Humaine, Bobigny, France; APHP, Service d'hépatologie, Hôpital Jean Verdier, Hôpitaux Universitaires Paris-Seine-Saint-Denis, Assistance-Publique Hôpitaux de Paris, Bondy, France.

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http://dx.doi.org/10.1016/j.jhep.2016.03.011DOI Listing
August 2016

Hepatocellular adenoma with malignant transformation in a patient with neonatal portal vein thrombosis.

Hepatology 2016 08 27;64(2):675-7. Epub 2016 May 27.

Sorbonne Universités, UPMC, Paris VI, Paris, France.

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http://dx.doi.org/10.1002/hep.28590DOI Listing
August 2016

Translating the molecular diversity of hepatocellular carcinoma into clinical practice.

Mol Cell Oncol 2016 Jul 1;3(4):e1057316. Epub 2015 Sep 1.

Inserm, UMR-1162, Génomique fonctionnelle des Tumeurs solides, Equipe Labellisée Ligue Contre le Cancer, Institut Universitaire d'Hématologie, Paris, France; Université Paris Descartes, Labex Immuno-Oncology, Sorbonne Paris Cité, Faculté de Médecine, Paris, France; Université Paris 13, Bobigny, France; Université Paris Diderot, Paris, France; Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France.

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http://dx.doi.org/10.1080/23723556.2015.1057316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972123PMC
July 2016

Mechanisms of HBV-induced hepatocellular carcinoma.

J Hepatol 2016 Apr;64(1 Suppl):S84-S101

Inserm, UMR-1162, Génomique Fonctionnelle des Tumeurs Solides, Equipe Labellisée Ligue Contre le Cancer, Institut Universitaire d'Hematologie, Paris, France; Université Paris Descartes, Labex Immuno-Oncology, Sorbonne Paris Cité, Faculté de Médecine, Paris, France; Université Paris 13, Sorbonne Paris Cité, Unité de Formation et de Recherche Santé, Médecine, Biologie Humaine, Bobigny, France; Université Paris Diderot, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2016.02.021DOI Listing
April 2016

Hepatocellular carcinoma.

Nat Rev Dis Primers 2016 04 14;2:16018. Epub 2016 Apr 14.

Mayo Clinic, Mayo College of Medicine, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1038/nrdp.2016.18DOI Listing
April 2016

AAV2 and Hepatocellular Carcinoma.

Hum Gene Ther 2016 Mar;27(3):211-3

1 INSERM, UMR-1162, Génomique fonctionnelle des Tumeurs solides, Equipe Labellisée Ligue Contre le Cancer , Paris, France.

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http://dx.doi.org/10.1089/hum.2016.002DOI Listing
March 2016

Adeno-associated virus type 2 as an oncogenic virus in human hepatocellular carcinoma.

Mol Cell Oncol 2016 Mar 19;3(2):e1095271. Epub 2016 Jan 19.

Inserm, UMR-1162, Génomique fonctionnelle des Tumeurs solides, Equipe Labellisée Ligue Contre le Cancer, Paris, F-75010 France; Université Paris Descartes, Labex Immuno-Oncology, Sorbonne Paris Cité, Faculté de Médecine, Paris, France; Université Paris 13, Sorbonne Paris Cité, UFR SMBH, F-93000 Bobigny, France; Université Paris Diderot, F-75013 Paris; Assistance Publique-Hôpitaux de Paris, Hopital Europeen Georges Pompidou, F-75015 Paris, France.

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http://dx.doi.org/10.1080/23723556.2015.1095271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905403PMC
March 2016

TERT promoter mutations in primary liver tumors.

Clin Res Hepatol Gastroenterol 2016 Feb 31;40(1):9-14. Epub 2015 Aug 31.

Inserm, UMR-1162, Génomique fonctionnelle des Tumeurs solides, Équipe Labellisée Ligue Contre le Cancer, 75010 Paris, France; Université Paris Descartes, Labex Immuno-Oncology, Sorbonne Paris Cité, Faculté de Médecine, 75006 Paris, France; Université Paris 13, Sorbonne Paris Cité, UFR SMBH, 93000 Bobigny, France; Université Paris Diderot, 75013 Paris, France; Assistance publique-Hôpitaux de Paris, Hôpital Européen Georges-Pompidou, 75015 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.clinre.2015.07.006DOI Listing
February 2016

Inflammatory hepatocellular adenomas developed in the setting of chronic liver disease and cirrhosis.

Mod Pathol 2016 Jan 30;29(1):43-50. Epub 2015 Oct 30.

Inserm, UMR-1162, Génomique fonctionnelle des Tumeurs solides, Equipe Labellisée Ligue Contre le Cancer, Paris, France.

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http://dx.doi.org/10.1038/modpathol.2015.119DOI Listing
January 2016

Prognostic and theranostic impact of molecular subtypes and immune classifications in renal cell cancer (RCC) and colorectal cancer (CRC).

Oncoimmunology 2015 Dec 7;4(12):e1049804. Epub 2015 Aug 7.

INSERM UMR_S 1138 Cancer; Immune Control and Escape; Cordeliers Research Centre ; Paris, France ; Université Paris Descartes; Sorbonne Paris Cité; UMR_S 1338; Cordeliers Research Centre ; Paris, France ; Sorbonne Universités; UPMC Univ Paris 06; UMR_S 1138; Cordeliers Research Centre ; Paris, France ; Assistance Publique-Hôpitaux de Paris; Hôpital Européen Georges Pompidou, Department of Biology , Paris, France.

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http://dx.doi.org/10.1080/2162402X.2015.1049804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635888PMC
December 2015

Mutations leading to constitutive active gp130/JAK1/STAT3 pathway.

Cytokine Growth Factor Rev 2015 Oct 3;26(5):499-506. Epub 2015 Jul 3.

Inserm, UMR-1162, Génomique fonctionnelle des Tumeurs solides, Equipe Labellisée Ligue Contre le Cancer, Paris F-75010, France; Université Paris Descartes, Labex Immuno-Oncology, Sorbonne Paris Cité, Faculté de Médecine, Paris, France; Université Paris 13, Sorbonne Paris Cité, UFR SMBH, F-93000 Bobigny, France; Université Paris Diderot, F-75013 Paris, France; Assistance Publique-Hôpitaux de Paris, Hopital Europeen Georges Pompidou, F-75015 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.cytogfr.2015.07.010DOI Listing
October 2015

Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas.

Nat Genet 2015 Oct 24;47(10):1187-93. Epub 2015 Aug 24.

INSERM, Unité Mixte de Recherche (UMR) 1162, Génomique Fonctionnelle des Tumeurs Solides, Equipe Labellisée Ligue contre le Cancer, Paris, France.

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http://dx.doi.org/10.1038/ng.3389DOI Listing
October 2015

Kidney cancer: Single nucleotide polymorphisms in mRCC-is their time up?

Nat Rev Urol 2015 Aug 30;12(8):424-6. Epub 2015 Jun 30.

Inserm, UMR-1162, Génomique fonctionnelle des tumeurs solides, Institut Universitaire d'Hématologie (IUH), Rue Juliette Dodu 27, F-75010 Paris, France.

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http://www.nature.com/articles/nrurol.2015.149
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http://dx.doi.org/10.1038/nrurol.2015.149DOI Listing
August 2015