Publications by authors named "Jessica L Mega"

56Publications

Pharmacology of antithrombotic drugs: an assessment of oral antiplatelet and anticoagulant treatments.

Lancet 2015 Jul 14;386(9990):281-91. Epub 2015 Mar 14.

Assistance Publique-Hôpitaux de Paris, Hôpital Saint Antoine, Department of Clinical Pharmacology and Unité de Recherche Clinique (URCEST), Paris, France; Université Pierre et Marie Curie, Paris, France; Institut National de la Santé et de la Recherche Médicale, National Institute of Health and Medical Research, U-698, Paris, France.

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July 2015

Difference or disparity: will big data improve our understanding of sex and cardiovascular disease?

Circ Cardiovasc Qual Outcomes 2015 Mar 24;8(2 Suppl 1):S52-5. Epub 2015 Feb 24.

From the Department of Medicine, Division of Cardiovascular Medicine (K.E.J., J.L.M., M.L.O.), TIMI Study Group (J.L.M., M.L.O.), Brigham and Women's Hospital and Harvard Medical School, Boston, MA; and Office of the Assistant Secretary for Planning and Evaluation, US Department of Health and Human Services, Washington, DC (K.E.J.).

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March 2015

Pharmacogenomics of antiplatelet drugs.

Hematology Am Soc Hematol Educ Program 2014 Dec 18;2014(1):343-7. Epub 2014 Nov 18.

TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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December 2014

Role of oral anticoagulants in patients after an acute coronary syndrome.

Arterioscler Thromb Vasc Biol 2015 Mar 22;35(3):520-4. Epub 2015 Jan 22.

From the TIMI Study Group (J.L.M.), Division of Cardiovascular Medicine (E.T.C., J.L.M.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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March 2015

World heart federation expert consensus statement on antiplatelet therapy in east asian patients with ACS or undergoing PCI.

Glob Heart 2014 Dec 26;9(4):457-67. Epub 2014 Aug 26.

Division of Cardiology, University of North Carolina, Chapel Hill, North Carolina, USA. Electronic address:

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December 2014

Duration of anticoagulation for venous thromboembolic events.

Circulation 2014 Dec;130(25):2343-8

From the Division of Cardiology, Department of Medicine (N.R.S., J.S.B.), Division of Hematology, Department of Medicine (J.S.B.), and Division of Vascular Surgery, Department of Surgery (J.S.B.), New York University School of Medicine, New York, NY; and Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (J.L.M.).

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December 2014

Population and personalized medicine in the modern era.

JAMA 2014 Nov;312(19):1969-70

TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts2American Heart Association, Dallas, Texas.

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November 2014

The effect of rivaroxaban on myocardial infarction in the ATLAS ACS 2 - TIMI 51 trial.

Eur Heart J Acute Cardiovasc Care 2015 Oct 15;4(5):468-74. Epub 2014 Oct 15.

TIMI Study Group, Heart & Vascular Center, Brigham and Women's Hospital and Harvard Medical School, USA

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October 2015

Expert consensus document: World Heart Federation expert consensus statement on antiplatelet therapy in East Asian patients with ACS or undergoing PCI.

Nat Rev Cardiol 2014 Oct 26;11(10):597-606. Epub 2014 Aug 26.

Division of Cardiology, University of North Carolina, 160 Dental Circle, CB 7075, Chapel Hill, NC 27599, USA.

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October 2014

Increases in myocardial workload induced by rapid atrial pacing trigger alterations in global metabolism.

PLoS One 2014 16;9(6):e99058. Epub 2014 Jun 16.

Department of Internal Medicine, Division of Cardiology, Massachusetts General Hospital, Boston, Massachusetts, United States of America.

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October 2015

Dual antiplatelet therapy for heart disease.

Circulation 2014 May;129(21):e506-8

From the Internal Medicine Department (E.T.C.) and TIMI Study Group, Cardiovascular Division (J.L.M.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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May 2014

Genotype-guided dosing of warfarin.

Clin Chem 2014 Jul 1;60(7):920-2. Epub 2014 Apr 1.

Thrombolysis in Myocardial Infarction Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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July 2014

Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study.

Authors:
Michael V Holmes Tabassome Simon Holly J Exeter Lasse Folkersen Folkert W Asselbergs Montse Guardiola Jackie A Cooper Jutta Palmen Jaroslav A Hubacek Kathryn F Carruthers Benjamin D Horne Kimberly D Brunisholz Jessica L Mega Erik P A van Iperen Mingyao Li Maarten Leusink Stella Trompet Jeffrey J W Verschuren G Kees Hovingh Abbas Dehghan Christopher P Nelson Salma Kotti Nicolas Danchin Markus Scholz Christiane L Haase Dietrich Rothenbacher Daniel I Swerdlow Karoline B Kuchenbaecker Eleonora Staines-Urias Anuj Goel Ferdinand van 't Hooft Karl Gertow Ulf de Faire Andrie G Panayiotou Elena Tremoli Damiano Baldassarre Fabrizio Veglia Lesca M Holdt Frank Beutner Ron T Gansevoort Gerjan J Navis Irene Mateo Leach Lutz P Breitling Hermann Brenner Joachim Thiery Dhayana Dallmeier Anders Franco-Cereceda Jolanda M A Boer Jeffrey W Stephens Marten H Hofker Alain Tedgui Albert Hofman André G Uitterlinden Vera Adamkova Jan Pitha N Charlotte Onland-Moret Maarten J Cramer Hendrik M Nathoe Wilko Spiering Olaf H Klungel Meena Kumari Peter H Whincup David A Morrow Peter S Braund Alistair S Hall Anders G Olsson Pieter A Doevendans Mieke D Trip Martin D Tobin Anders Hamsten Hugh Watkins Wolfgang Koenig Andrew N Nicolaides Daniel Teupser Ian N M Day John F Carlquist Tom R Gaunt Ian Ford Naveed Sattar Sotirios Tsimikas Gregory G Schwartz Debbie A Lawlor Richard W Morris Manjinder S Sandhu Rudolf Poledne Anke H Maitland-van der Zee Kay-Tee Khaw Brendan J Keating Pim van der Harst Jackie F Price Shamir R Mehta Salim Yusuf Jaqueline C M Witteman Oscar H Franco J Wouter Jukema Peter de Knijff Anne Tybjaerg-Hansen Daniel J Rader Martin Farrall Nilesh J Samani Mika Kivimaki Keith A A Fox Steve E Humphries Jeffrey L Anderson S Matthijs Boekholdt Tom M Palmer Per Eriksson Guillaume Paré Aroon D Hingorani Marc S Sabatine Ziad Mallat Juan P Casas Philippa J Talmud

J Am Coll Cardiol 2013 Nov 31;62(21):1966-1976. Epub 2013 Jul 31.

Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, London, United Kingdom.

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November 2013

Autoantibodies to phosphorylcholine and cardiovascular outcomes in patients with acute coronary syndromes in the ATLAS ACS-TIMI 46 trial.

J Thromb Thrombolysis 2014 Apr;37(3):310-6

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 350 Longwood Avenue, First Floor, Boston, MA, USA,

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April 2014

Balancing antiplatelet and anticoagulant therapies in patients with cardiovascular disease.

Cardiol Ther 2013 Jun 25;2(1):85-96. Epub 2013 Apr 25.

Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, Boston, MA, 02115, USA,

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June 2013

Comparison of the efficacy and safety of two rivaroxaban doses in acute coronary syndrome (from ATLAS ACS 2-TIMI 51).

Am J Cardiol 2013 Aug 24;112(4):472-8. Epub 2013 May 24.

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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August 2013

Antithrombotic treatment in transcatheter aortic valve implantation: insights for cerebrovascular and bleeding events.

J Am Coll Cardiol 2013 Dec 10;62(25):2349-2359. Epub 2013 Apr 10.

Division of Cardiovascular Medicine, Duke University Medical Center, Durham, North Carolina; Divisions of Cardiology and Hematology, Duke University Medical Center, Durham, North Carolina.

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December 2013

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.

Authors:
Richa Saxena Clara C Elbers Yiran Guo Inga Peter Tom R Gaunt Jessica L Mega Matthew B Lanktree Archana Tare Berta Almoguera Castillo Yun R Li Toby Johnson Marcel Bruinenberg Diane Gilbert-Diamond Ramakrishnan Rajagopalan Benjamin F Voight Ashok Balasubramanyam John Barnard Florianne Bauer Jens Baumert Tushar Bhangale Bernhard O Böhm Peter S Braund Paul R Burton Hareesh R Chandrupatla Robert Clarke Rhonda M Cooper-DeHoff Errol D Crook George Davey-Smith Ian N Day Anthonius de Boer Mark C H de Groot Fotios Drenos Jane Ferguson Caroline S Fox Clement E Furlong Quince Gibson Christian Gieger Lisa A Gilhuijs-Pederson Joseph T Glessner Anuj Goel Yan Gong Struan F A Grant Diederick E Grobbee Claire Hastie Steve E Humphries Cecilia E Kim Mika Kivimaki Marcus Kleber Christa Meisinger Meena Kumari Taimour Y Langaee Debbie A Lawlor Mingyao Li Maximilian T Lobmeyer Anke-Hilse Maitland-van der Zee Matthijs F L Meijs Cliona M Molony David A Morrow Gurunathan Murugesan Solomon K Musani Christopher P Nelson Stephen J Newhouse Jeffery R O'Connell Sandosh Padmanabhan Jutta Palmen Sanjey R Patel Carl J Pepine Mary Pettinger Thomas S Price Suzanne Rafelt Jane Ranchalis Asif Rasheed Elisabeth Rosenthal Ingo Ruczinski Sonia Shah Haiqing Shen Günther Silbernagel Erin N Smith Annemieke W M Spijkerman Alice Stanton Michael W Steffes Barbara Thorand Mieke Trip Pim van der Harst Daphne L van der A Erik P A van Iperen Jessica van Setten Jana V van Vliet-Ostaptchouk Niek Verweij Bruce H R Wolffenbuttel Taylor Young M Hadi Zafarmand Joseph M Zmuda Michael Boehnke David Altshuler Mark McCarthy W H Linda Kao James S Pankow Thomas P Cappola Peter Sever Neil Poulter Mark Caulfield Anna Dominiczak Denis C Shields Deepak L Bhatt Deepak Bhatt Li Zhang Sean P Curtis John Danesh Juan P Casas Yvonne T van der Schouw N Charlotte Onland-Moret Pieter A Doevendans Gerald W Dorn Martin Farrall Garret A FitzGerald Anders Hamsten Robert Hegele Aroon D Hingorani Marten H Hofker Gordon S Huggins Thomas Illig Gail P Jarvik Julie A Johnson Olaf H Klungel William C Knowler Wolfgang Koenig Winfried März James B Meigs Olle Melander Patricia B Munroe Braxton D Mitchell Susan J Bielinski Daniel J Rader Muredach P Reilly Stephen S Rich Jerome I Rotter Danish Saleheen Nilesh J Samani Eric E Schadt Alan R Shuldiner Roy Silverstein Kandice Kottke-Marchant Philippa J Talmud Hugh Watkins Folkert W Asselbergs Folkert Asselbergs Paul I W de Bakker Jeanne McCaffery Cisca Wijmenga Marc S Sabatine James G Wilson Alex Reiner Donald W Bowden Hakon Hakonarson David S Siscovick Brendan J Keating

Am J Hum Genet 2012 Mar 9;90(3):410-25. Epub 2012 Feb 9.

Center for Human Genetic Research, Massachusetts General Hospital, Boston, 02114, USA.

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March 2012

A new era for anticoagulation in atrial fibrillation.

Authors:
Jessica L Mega

N Engl J Med 2011 Sep 27;365(11):1052-4. Epub 2011 Aug 27.

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September 2011

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.

Authors:
Matthew B Lanktree Yiran Guo Muhammed Murtaza Joseph T Glessner Swneke D Bailey N Charlotte Onland-Moret Guillaume Lettre Halit Ongen Ramakrishnan Rajagopalan Toby Johnson Haiqing Shen Christopher P Nelson Norman Klopp Jens Baumert Sandosh Padmanabhan Nathan Pankratz James S Pankow Sonia Shah Kira Taylor John Barnard Bas J Peters Cliona M Maloney Maximilian T Lobmeyer Alice Stanton M Hadi Zafarmand Simon P R Romaine Amar Mehta Erik P A van Iperen Yan Gong Tom S Price Erin N Smith Cecilia E Kim Yun R Li Folkert W Asselbergs Larry D Atwood Kristian M Bailey Deepak Bhatt Florianne Bauer Elijah R Behr Tushar Bhangale Jolanda M A Boer Bernhard O Boehm Jonathan P Bradfield Morris Brown Peter S Braund Paul R Burton Cara Carty Hareesh R Chandrupatla Wei Chen John Connell Chrysoula Dalgeorgou Anthonius de Boer Fotios Drenos Clara C Elbers James C Fang Caroline S Fox Edward C Frackelton Barry Fuchs Clement E Furlong Quince Gibson Christian Gieger Anuj Goel Diederik E Grobbee Claire Hastie Philip J Howard Guan-Hua Huang W Craig Johnson Qing Li Marcus E Kleber Barbara E K Klein Ronald Klein Charles Kooperberg Bonnie Ky Andrea Lacroix Paul Lanken Mark Lathrop Mingyao Li Vanessa Marshall Olle Melander Frank D Mentch Nuala J Meyer Keri L Monda Alexandre Montpetit Gurunathan Murugesan Karen Nakayama Dave Nondahl Abiodun Onipinla Suzanne Rafelt Stephen J Newhouse F George Otieno Sanjey R Patel Mary E Putt Santiago Rodriguez Radwan N Safa Douglas B Sawyer Pamela J Schreiner Claire Simpson Suthesh Sivapalaratnam Sathanur R Srinivasan Christine Suver Gary Swergold Nancy K Sweitzer Kelly A Thomas Barbara Thorand Nicholas J Timpson Sam Tischfield Martin Tobin Maciej Tomaszewski Maciej Tomaszweski W M Monique Verschuren Chris Wallace Bernhard Winkelmann Haitao Zhang Dongling Zheng Li Zhang Joseph M Zmuda Robert Clarke Anthony J Balmforth John Danesh Ian N Day Nicholas J Schork Paul I W de Bakker Christian Delles David Duggan Aroon D Hingorani Joel N Hirschhorn Marten H Hofker Steve E Humphries Mika Kivimaki Debbie A Lawlor Kandice Kottke-Marchant Jessica L Mega Braxton D Mitchell David A Morrow Jutta Palmen Susan Redline Denis C Shields Alan R Shuldiner Patrick M Sleiman George Davey Smith Martin Farrall Yalda Jamshidi David C Christiani Juan P Casas Alistair S Hall Pieter A Doevendans Jason D Christie Gerald S Berenson Sarah S Murray Thomas Illig Gerald W Dorn Thomas P Cappola Eric Boerwinkle Peter Sever Daniel J Rader Muredach P Reilly Mark Caulfield Philippa J Talmud Eric Topol James C Engert Kai Wang Anna Dominiczak Anders Hamsten Sean P Curtis Roy L Silverstein Leslie A Lange Marc S Sabatine Mieke Trip Danish Saleheen John F Peden Karen J Cruickshanks Winfried März Jeffrey R O'Connell Olaf H Klungel Cisca Wijmenga Anke Hilse Maitland-van der Zee Eric E Schadt Julie A Johnson Gail P Jarvik George J Papanicolaou Struan F A Grant Patricia B Munroe Kari E North Nilesh J Samani Wolfgang Koenig Tom R Gaunt Sonia S Anand Yvonne T van der Schouw Nicole Soranzo Garret A Fitzgerald Alex Reiner Robert A Hegele Hakon Hakonarson Brendan J Keating

Am J Hum Genet 2011 Jan 30;88(1):6-18. Epub 2010 Dec 30.

Department of Medicine and Biochemistry, University of Western Ontario, London, Ontario, N6A 5C1, Canada.

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January 2011

Identification of genetic variants associated with response to statin therapy.

Arterioscler Thromb Vasc Biol 2009 Sep 10;29(9):1310-5. Epub 2009 Aug 10.

Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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September 2009

Cytochrome P450 genetic polymorphisms and the response to prasugrel: relationship to pharmacokinetic, pharmacodynamic, and clinical outcomes.

Circulation 2009 May 4;119(19):2553-60. Epub 2009 May 4.

Thrombolysis in Myocardial Infarction Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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May 2009

Interaction between cigarette smoking and clinical benefit of clopidogrel.

J Am Coll Cardiol 2009 Apr;53(15):1273-8

Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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April 2009

Cytochrome p-450 polymorphisms and response to clopidogrel.

N Engl J Med 2009 Jan 22;360(4):354-62. Epub 2008 Dec 22.

Thrombolysis in Myocardial Infarction Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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January 2009

Thrombus precursor protein and clinical outcomes in patients with acute coronary syndromes.

J Am Coll Cardiol 2008 Jun;51(25):2422-9

TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.

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June 2008

Outcomes and optimal antithrombotic therapy in women undergoing fibrinolysis for ST-elevation myocardial infarction.

Circulation 2007 Jun 21;115(22):2822-8. Epub 2007 May 21.

TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital and Department of Medicine, Harvard Medical School, Boston, Mass 02115, USA.

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June 2007

Meta-analysis of cardiovascular outcomes trials comparing intensive versus moderate statin therapy.

J Am Coll Cardiol 2006 Aug 12;48(3):438-45. Epub 2006 Jul 12.

Thrombolysis In Myocardial Infarction Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.

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August 2006

Dynamic aortic obstruction in a patient with acute type B dissection.

Cardiol Rev 2006 May-Jun;14(3):151-4

Brigham and Women's Hospital, Boston, Massachusetts, USA.

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September 2006