Jesse S Boehm

Jesse S Boehm

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Jesse S Boehm

Jesse S Boehm

Publications by authors named "Jesse S Boehm"

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From cell lines to living biosensors: new opportunities to prioritize cancer dependencies using ex vivo tumor cultures.

Curr Opin Genet Dev 2019 02 28;54:33-40. Epub 2019 Mar 28.

Broad Institute of Harvard and MIT, Cambridge, MA, 02142, United States. Electronic address:

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http://dx.doi.org/10.1016/j.gde.2019.02.007DOI Listing
February 2019

Functional Genomic Characterization of Cancer Genomes.

Cold Spring Harb Symp Quant Biol 2016 4;81:237-246. Epub 2016 Nov 4.

Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02215.

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http://dx.doi.org/10.1101/sqb.2016.81.031070DOI Listing
February 2018

Patient-derived xenografts undergo mouse-specific tumor evolution.

Nat Genet 2017 Nov 9;49(11):1567-1575. Epub 2017 Oct 9.

Cancer Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659952PMC
November 2017

Emerging Opportunities for Target Discovery in Rare Cancers.

Cell Chem Biol 2017 Sep;24(9):1075-1091

Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2017.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857178PMC
September 2017

Defining a Cancer Dependency Map.

Cell 2017 Jul;170(3):564-576.e16

Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA, USA; Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, USA; Department of Medicine, Brigham and Women's Hospital, 75 Francis Street, Boston, MA, USA; Harvard Medical School, 25 Shattuck Street, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.06.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667678PMC
July 2017

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

Cell Syst 2016 09;3(3):302-316.e4

Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Avenue, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2016.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455996PMC
September 2016

Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.

Sci Data 2014 30;1:140035. Epub 2014 Sep 30.

Broad Institute of Harvard and MIT, 7 Cambridge Center , Cambridge, Massachusetts 02142, USA ; Department of Medical, Dana-Farber Cancer Institute , 450 Brookline Avenue, Boston, Massachusetts 02215, USA ; Center for Cancer Genome Discovery, Dana-Farber Cancer Institute , 450 Brookline Avenue, Boston, Massachusetts 02215, USA ; Departments of Medicine, Brigham and Women's Hospital, Harvard Medical School , Boston, Massachusetts 02115, USA.

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http://www.nature.com/articles/sdata201435
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http://dx.doi.org/10.1038/sdata.2014.35DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432652PMC
February 2016

An ecosystem of cancer cell line factories to support a cancer dependency map.

Nat Rev Genet 2015 Jul 16;16(7):373-4. Epub 2015 Jun 16.

1] Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, Massachusetts 02142, USA. [2] Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, Massachusetts 02215, USA. [3] Harvard Medical School, 25 Shattuck Street, Boston, Massachusetts 02115, USA. [4] Howard Hughes Medical Institute, 4000 Jones Bridge Road, Chevy Chase, Maryland 20815, USA.

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http://dx.doi.org/10.1038/nrg3967DOI Listing
July 2015

Building the Connectivity Map of epigenetics: chromatin profiling by quantitative targeted mass spectrometry.

Methods 2015 Jan 6;72:57-64. Epub 2014 Nov 6.

The Broad Institute of MIT and Harvard University, 415 Main St., Cambridge, MA 02142, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2014.10.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300274PMC
January 2015

Towards systematic functional characterization of cancer genomes.

Nat Rev Genet 2011 Jun 17;12(7):487-98. Epub 2011 Jun 17.

Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA.

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http://www.nature.com/articles/nrg3013
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http://dx.doi.org/10.1038/nrg3013DOI Listing
June 2011

Functional genomics and cancer drug target discovery.

Curr Opin Mol Ther 2010 Jun;12(3):284-93

Dana-Farber Cancer Institute, Department of Medical Oncology, 44 Binney Street, Boston, MA 02115, USA.

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June 2010

Control of cyclin D1 and breast tumorigenesis by the EglN2 prolyl hydroxylase.

Cancer Cell 2009 Nov;16(5):413-24

Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.ccr.2009.09.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788761PMC
November 2009

Integrative genomic approaches to understanding cancer.

Biochim Biophys Acta 2009 Jun 11;1790(6):478-84. Epub 2009 Feb 11.

Center for Cancer Genome Discovery, Department of Medical Oncology, Dana-Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.bbagen.2009.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692376PMC
June 2009

Cancer genetics: Finding the right mix.

Eur J Hum Genet 2005 Oct;13(10):1099-100

Department of Medical Oncology, Dana-Farber Cancer Institute, 44 Binney St., Dana 710C, Boston, MA 02115-6013, USA.

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http://www.nature.com/articles/5201477
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http://dx.doi.org/10.1038/sj.ejhg.5201477DOI Listing
October 2005

Transformation of human and murine fibroblasts without viral oncoproteins.

Mol Cell Biol 2005 Aug;25(15):6464-74

Department of Medical Oncology, Dana-Farber Cancer Institute, 44 Binney St., Dana 710C, Boston, MA 02115-6013, USA.

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http://dx.doi.org/10.1128/MCB.25.15.6464-6474.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1190359PMC
August 2005

Understanding transformation: progress and gaps.

Curr Opin Genet Dev 2005 Feb;15(1):13-7

Department of Medical Oncology, Dana-Farber Cancer Institute, Departments of Medicine and Pathology, Harvard Medical School, 44 Binney Street, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.gde.2004.11.003DOI Listing
February 2005

Immortalized cells as experimental models to study cancer.

Cytotechnology 2004 Jun;45(1-2):47-59

Department of Medical Oncology, Department of Medicine, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston, MA, 02115, USA.

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http://link.springer.com/10.1007/s10616-004-5125-1
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http://dx.doi.org/10.1007/s10616-004-5125-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449965PMC
June 2004