Jesper H Svendsen

Jesper H Svendsen

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Jesper H Svendsen

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Genetic variants on chromosomes 7p31 and 12p12 are associated with abnormal atrial electrical activation in patients with early-onset lone atrial fibrillation.

Ann Noninvasive Electrocardiol 2019 Nov 1;24(6):e12661. Epub 2019 Jun 1.

The Center for Integrative Electrocardiology, Arrhythmia Clinic Skåne University Hospital, Lund University (CIEL), Lund, Sweden.

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http://dx.doi.org/10.1111/anec.12661DOI Listing
November 2019

Relationship between left atrial strain, diastolic dysfunction and subclinical atrial fibrillation in patients with cryptogenic stroke: the SURPRISE echo substudy.

Int J Cardiovasc Imaging 2019 Oct 8. Epub 2019 Oct 8.

Cardiovascular Non-Invasive Imaging Research Laboratory (CIRL), Department of Cardiology, Herlev & Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.

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http://dx.doi.org/10.1007/s10554-019-01700-yDOI Listing
October 2019

Effect of diabetes duration on the relationship between glycaemic control and risk of death in older adults with type 2 diabetes.

Diabetes Obes Metab 2019 Oct 9. Epub 2019 Oct 9.

Laboratory for Molecular Cardiology, Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/dom.13891DOI Listing
October 2019

Risk Models for Prediction of Implantable Cardioverter-Defibrillator Benefit: Insights From the DANISH Trial.

JACC Heart Fail 2019 Aug 10;7(8):717-724. Epub 2019 Jul 10.

Department of Cardiology, Bispebjerg University Hospital, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.jchf.2019.03.019DOI Listing
August 2019

Shortening of paced QRS duration after electrocardiographic optimization of left ventricular pacing vector in patients treated with Cardiac Resynchronization Therapy.

J Electrocardiol 2018 Jul - Aug;51(4):628-633. Epub 2018 Apr 25.

Department of Cardiology, The Heart Centre, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, DK-2100 Copenhagen East, Denmark.

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http://dx.doi.org/10.1016/j.jelectrocard.2018.04.016DOI Listing
May 2019

Primary Prevention of Sudden Cardiac Death With Implantable Cardioverter-Defibrillator Therapy in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy.

Am J Cardiol 2019 Apr 8;123(7):1156-1162. Epub 2019 Jan 8.

Department of Cardiology, The Heart Center, Rigshospitalet, University of Copenhagen, Denmark & Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.amjcard.2018.12.049DOI Listing
April 2019

Exercise-based cardiac rehabilitation for adult patients with an implantable cardioverter defibrillator.

Cochrane Database Syst Rev 2019 02 12;2:CD011828. Epub 2019 Feb 12.

Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, Copenhagen, Denmark, 2100.

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http://doi.wiley.com/10.1002/14651858.CD011828.pub2
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http://dx.doi.org/10.1002/14651858.CD011828.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371011PMC
February 2019

Visit-to-Visit Variability of Hemoglobin A in People Without Diabetes and Risk of Major Adverse Cardiovascular Events and All-Cause Mortality.

Diabetes Care 2019 01 23;42(1):134-141. Epub 2018 Oct 23.

Laboratory of Molecular Cardiology, Department of Cardiology, Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark

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http://care.diabetesjournals.org/lookup/doi/10.2337/dc18-139
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http://dx.doi.org/10.2337/dc18-1396DOI Listing
January 2019

Mortality and Heart Failure Hospitalization in Patients With Conduction Abnormalities After Transcatheter Aortic Valve Replacement.

JACC Cardiovasc Interv 2019 01;12(1):52-61

Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

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https://linkinghub.elsevier.com/retrieve/pii/S19368798183223
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http://dx.doi.org/10.1016/j.jcin.2018.10.053DOI Listing
January 2019

Precision of automated QRS duration measurement in patients treated with cardiac resynchronization therapy.

J Interv Card Electrophysiol 2018 Jun 5;52(1):103-110. Epub 2018 Mar 5.

Department of Cardiology, The Heart Centre, Copenhagen University Hospital Rigshospitalet, Blegdamsvej 9, DK-2100, Copenhagen, Denmark.

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http://link.springer.com/10.1007/s10840-018-0334-2
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http://dx.doi.org/10.1007/s10840-018-0334-2DOI Listing
June 2018

Multi-ethnic genome-wide association study for atrial fibrillation.

Authors:
Carolina Roselli Mark D Chaffin Lu-Chen Weng Stefanie Aeschbacher Gustav Ahlberg Christine M Albert Peter Almgren Alvaro Alonso Christopher D Anderson Krishna G Aragam Dan E Arking John Barnard Traci M Bartz Emelia J Benjamin Nathan A Bihlmeyer Joshua C Bis Heather L Bloom Eric Boerwinkle Erwin B Bottinger Jennifer A Brody Hugh Calkins Archie Campbell Thomas P Cappola John Carlquist Daniel I Chasman Lin Y Chen Yii-Der Ida Chen Eue-Keun Choi Seung Hoan Choi Ingrid E Christophersen Mina K Chung John W Cole David Conen James Cook Harry J Crijns Michael J Cutler Scott M Damrauer Brian R Daniels Dawood Darbar Graciela Delgado Joshua C Denny Martin Dichgans Marcus Dörr Elton A Dudink Samuel C Dudley Nada Esa Tonu Esko Markku Eskola Diane Fatkin Stephan B Felix Ian Ford Oscar H Franco Bastiaan Geelhoed Raji P Grewal Vilmundur Gudnason Xiuqing Guo Namrata Gupta Stefan Gustafsson Rebecca Gutmann Anders Hamsten Tamara B Harris Caroline Hayward Susan R Heckbert Jussi Hernesniemi Lynne J Hocking Albert Hofman Andrea R V R Horimoto Jie Huang Paul L Huang Jennifer Huffman Erik Ingelsson Esra Gucuk Ipek Kaoru Ito Jordi Jimenez-Conde Renee Johnson J Wouter Jukema Stefan Kääb Mika Kähönen Yoichiro Kamatani John P Kane Adnan Kastrati Sekar Kathiresan Petra Katschnig-Winter Maryam Kavousi Thorsten Kessler Bas L Kietselaer Paulus Kirchhof Marcus E Kleber Stacey Knight Jose E Krieger Michiaki Kubo Lenore J Launer Jari Laurikka Terho Lehtimäki Kirsten Leineweber Rozenn N Lemaitre Man Li Hong Euy Lim Henry J Lin Honghuang Lin Lars Lind Cecilia M Lindgren Marja-Liisa Lokki Barry London Ruth J F Loos Siew-Kee Low Yingchang Lu Leo-Pekka Lyytikäinen Peter W Macfarlane Patrik K Magnusson Anubha Mahajan Rainer Malik Alfredo J Mansur Gregory M Marcus Lauren Margolin Kenneth B Margulies Winfried März David D McManus Olle Melander Sanghamitra Mohanty Jay A Montgomery Michael P Morley Andrew P Morris Martina Müller-Nurasyid Andrea Natale Saman Nazarian Benjamin Neumann Christopher Newton-Cheh Maartje N Niemeijer Kjell Nikus Peter Nilsson Raymond Noordam Heidi Oellers Morten S Olesen Marju Orho-Melander Sandosh Padmanabhan Hui-Nam Pak Guillaume Paré Nancy L Pedersen Joanna Pera Alexandre Pereira David Porteous Bruce M Psaty Sara L Pulit Clive R Pullinger Daniel J Rader Lena Refsgaard Marta Ribasés Paul M Ridker Michiel Rienstra Lorenz Risch Dan M Roden Jonathan Rosand Michael A Rosenberg Natalia Rost Jerome I Rotter Samir Saba Roopinder K Sandhu Renate B Schnabel Katharina Schramm Heribert Schunkert Claudia Schurman Stuart A Scott Ilkka Seppälä Christian Shaffer Svati Shah Alaa A Shalaby Jaemin Shim M Benjamin Shoemaker Joylene E Siland Juha Sinisalo Moritz F Sinner Agnieszka Slowik Albert V Smith Blair H Smith J Gustav Smith Jonathan D Smith Nicholas L Smith Elsayed Z Soliman Nona Sotoodehnia Bruno H Stricker Albert Sun Han Sun Jesper H Svendsen Toshihiro Tanaka Kahraman Tanriverdi Kent D Taylor Maris Teder-Laving Alexander Teumer Sébastien Thériault Stella Trompet Nathan R Tucker Arnljot Tveit Andre G Uitterlinden Pim Van Der Harst Isabelle C Van Gelder David R Van Wagoner Niek Verweij Efthymia Vlachopoulou Uwe Völker Biqi Wang Peter E Weeke Bob Weijs Raul Weiss Stefan Weiss Quinn S Wells Kerri L Wiggins Jorge A Wong Daniel Woo Bradford B Worrall Pil-Sung Yang Jie Yao Zachary T Yoneda Tanja Zeller Lingyao Zeng Steven A Lubitz Kathryn L Lunetta Patrick T Ellinor

Nat Genet 2018 06 11;50(9):1225-1233. Epub 2018 Jun 11.

Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.

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http://dx.doi.org/10.1038/s41588-018-0133-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136836PMC
June 2018

Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development.

Am J Hum Genet 2018 01 28;102(1):103-115. Epub 2017 Dec 28.

Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI 48109, USA; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim 7491, Norway; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777936PMC
January 2018

Analysis of 60 706 Exomes Questions the Role of De Novo Variants Previously Implicated in Cardiac Disease.

Circ Cardiovasc Genet 2017 Dec;10(6)

From the Laboratory for Molecular Cardiology, Institute for Biomedical Sciences, University of Copenhagen, Denmark (C.P.-M., G.A., J.G., J.H.S., S.H., M.S.O.); Laboratory for Molecular Cardiology, Department of Cardiology, Heart Centre at Rigshospitalet, Copenhagen University Hospital, Denmark (C.P.-M., G.A., J.G., J.H.S., S.H., M.S.O.); Danish National Research Foundation Centre for Cardiac Arrhythmia, Copenhagen, Denmark (C.P.-M., G.A., J.G., J.H.S., S.H., M.S.O.); and Department of Clinical Medicine, University of Copenhagen, Denmark (J.H.S., S.H.).

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http://dx.doi.org/10.1161/CIRCGENETICS.117.001878DOI Listing
December 2017

The role of common genetic variants in atrial fibrillation.

J Electrocardiol 2016 Nov - Dec;49(6):864-870. Epub 2016 Aug 26.

Danish National Research Foundation Centre for Cardiac Arrhythmia, Copenhagen, Denmark; Laboratory for Molecular Cardiology, The Heart Centre, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.jelectrocard.2016.08.012DOI Listing
November 2017

Deep sequencing of atrial fibrillation patients with mitral valve regurgitation shows no evidence of mosaicism but reveals novel rare germline variants.

Heart Rhythm 2017 10 24;14(10):1531-1538. Epub 2017 May 24.

Danish National Research Foundation Centre for Cardiac Arrhythmia, University of Copenhagen, Copenhagen, Denmark; Laboratory for Molecular Cardiology, Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.hrthm.2017.05.027DOI Listing
October 2017

Chromogranin A in the mammalian heart: expression without secretion.

Biomark Med 2017 Jul 7;11(7):541-545. Epub 2017 Jul 7.

Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.2217/bmm-2017-0052DOI Listing
July 2017

Electrocardiographic Preexcitation and Risk of Cardiovascular Morbidity and Mortality: Results From the Copenhagen ECG Study.

Circ Arrhythm Electrophysiol 2017 Jun;10(6)

From the Laboratory for Molecular Cardiology, The Heart Centre, Rigshospitalet, Copenhagen, Denmark (M.W.S., P.V.R., J.G., M.S.O., S.H., J.H.S., A.G.H., J.B.N.); Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (S.H., L.K., J.H.S.); Department of Health Science and Technology, Aalborg University, Denmark (S.M.H., C.G., C.T.-P.); Copenhagen General Practitioners' Laboratory, Denmark (A.P.); and Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor (J.B.N.).

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http://dx.doi.org/10.1161/CIRCEP.116.004778DOI Listing
June 2017

Screening for Atrial Fibrillation: A Report of the AF-SCREEN International Collaboration.

Circulation 2017 05;135(19):1851-1867

From Heart Research Institute, Charles Perkins Centre, and Concord Hospital Cardiology, University of Sydney, Australia (B.F.); St Georges Hospital, London, UK (J.C.); Johns Hopkins University, Baltimore, MD (H.C.); Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada (J.S.H., D.C.); Karolinska Institute, Stockholm, Sweden (M.R., J.E., L.F., E.S.); The Shanghai Institute of Hypertension, Ruijin Hospital, Jiaotong University School of Medicine, China (J.W.); Brigham and Womens Hospital, Harvard Medical School, Boston, MA (C.M.A.); The George Institute for Global Health, Sydney, Australia (C.S.A.); Barts Health NHS Trust, London, UK (S.A.); National Heart, Lung, and Blood Institute and Boston University's Framingham Heart Study, MA (E.J.B.); University of Modena and Reggio Emilia, Italy (G.B.); Klinikum Coburg, Germany (J.B.); Odense University Hospital, Denmark (A.B.); Cardiovascular Research Centre, National Yang-Ming University, Taipei, Taiwan (T.- F.C.); University Hospital, Basel, Switzerland (D.C.); Université François Rabelais, Tours, France (L.F.); University of Birmingham, UK (D.A.F.); Mayo Clinic College of Medicine, Rochester, MN (B.J.G.); University of Toronto, Ontario, Canada (D.J.G., A.V.); Hackensack University Medical Centre, NJ (T.V.G.); Poche Centre, University of Sydney, Australia (K.G.); University of Western Australia, Perth (G.J.H.); Trinity College, Dublin, Ireland (J.H.); Royal Perth Hospital, University of Western Australia (G.S.H.); StopAfib.org, Dallas, TX (M.T.H.); Weill Cornell Medical College, New York (H.K.); Institute of Cardiovascular Sciences, University of Birmingham, UK (P.K.); SWBH and UHB NHS trusts, Birmingham, UK (P.K.); AFNET, Muenster, Germany (P.K.); Lankenau Institute for Medical Research, Wynnewood, OK (P.R.K.); University Hospital of Zurich, Switzerland (D.K.); Chinese University of Hong Kong (V.W.Y.L., B.P.Y.); University of Linköping, Sweden (L.-A.L.); University of Birmingham, UK; Aalborg University, Denmark (G.Y.H.L.); Arrhythmia Alliance, London, UK (T.L.); Charles Perkins Centre, University of Sydney, Australia (N.L.); Cliniques du Sud Luxembourg, Arlon, Belgium (G.H.M.); Institute for Epidemiology Statistics and Informatics, Frankfurt, Germany (C.M.); Edinburgh Napier University, UK (L.N.); Charles Perkins Centre, University of Sydney, Australia (J.O.); Duke University, Durham, NC (J.P.P.); University of Auckland, New Zealand (K.P.); University of Belgrade, Serbia (T.S.P.); KH der Elisabethinen, Ordensklinikum Linz, Austria (H.P.); University of Groningen, University Medical Centre Groningen, The Netherlands (M.R.); University of Alberta, Edmonton, Canada (R.K.S.); University Heart Centre, Hamburg, Germany (R.B.S.); The University of Hong Kong (C.-W.S.); Scripps Translational Science Institute, San Diego, CA (S.S.); Rigshospitalet, The Heart Centre, University of Copenhagen, Denmark (J.H.S.); Ospedale dell'Angelo Venice-Mestre, Venice, Italy (S.T.); Martini Hospital, Groningen, The Netherlands (R.G.T.); Stanford University, CA (M.P.T.); VA Palo Alto Health Care System, CA (M.P.T.); The Department of Medical Research, Bærum Hospital, Rud, Norway (A.T.); Department of General Practice, Academic Medical Center, Amsterdam, The Netherlands (S.B.U.); University of Groningen, University Medical Centre Groningen, The Netherlands (I.C.V.G.); and University of Göttingen, Germany (R.W.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.026693DOI Listing
May 2017

Exercise-based cardiac rehabilitation for adults with atrial fibrillation.

Cochrane Database Syst Rev 2017 02 9;2:CD011197. Epub 2017 Feb 9.

Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, Copenhagen, Denmark, 2100.

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http://dx.doi.org/10.1002/14651858.CD011197.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464537PMC
February 2017

Analyses of more than 60,000 exomes questions the role of numerous genes previously associated with dilated cardiomyopathy.

Mol Genet Genomic Med 2016 Nov 17;4(6):617-623. Epub 2016 Sep 17.

Laboratory of Molecular Cardiology Department of Cardiology The Heart Centre University Hospital of Copenhagen Rigshospitalet Copenhagen Denmark.

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http://dx.doi.org/10.1002/mgg3.245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118206PMC
November 2016

Association Between Heart Rate at Rest and Incident Atrial Fibrillation (from the Copenhagen Electrocardiographic Study).

Am J Cardiol 2016 09 14;118(5):708-13. Epub 2016 Jun 14.

Laboratory for Molecular Cardiology, Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan.

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http://dx.doi.org/10.1016/j.amjcard.2016.06.013DOI Listing
September 2016

Defibrillator Implantation in Patients with Nonischemic Systolic Heart Failure.

N Engl J Med 2016 09 27;375(13):1221-30. Epub 2016 Aug 27.

From the Department of Cardiology, Rigshospitalet (L.K., J.J.T., F.G., R.V., C.H., J.H.S., D.E.H., S.P.), and the Department of Cardiology, Bispebjerg Hospital (J.J.T.), University of Copenhagen, Copenhagen; the Department of Cardiology, Aarhus University Hospital, Aarhus (J.C.N., H.E.); the Department of Cardiology, Herlev and Gentofte Hospital, University of Copenhagen, Hellerup (J.H., N.E.B.); the Department of Cardiology, Odense University Hospital, Odense (L.V., A.B.); the Department of Cardiology, Aalborg University Hospital (E.K., A.M.T., C.T.-P.), and the Clinical Institute, Aalborg University (N.E.B.), Aalborg; the Department of Cardiology, Zealand University Hospital, Roskilde (G.J.); Frederiksberg Heart Clinic, Frederiksberg (P.H.); the Department of Cardiology, Lillebaelt Hospital, Vejle (F.H.S.); and the Department of Cardiology, Odense University Hospital, Svendborg (K.E.) - all in Denmark.

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http://dx.doi.org/10.1056/NEJMoa1608029DOI Listing
September 2016

Management of patients with Arrhythmogenic Right Ventricular Cardiomyopathy in the Nordic countries.

Scand Cardiovasc J 2015 23;49(6):299-307. Epub 2015 Sep 23.

i Dept. of Cardiology, The Heart Centre, Rigshospitalet, University of Copenhagen, and Danish National Research Foundation Centre for Cardiac Arrhythmia (DARC) , Copenhagen , Denmark and Department of Clinical Medicine , Faculty of Health and Medical Sciences, University of Copenhagen , Copenhagen , Denmark.

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http://dx.doi.org/10.3109/14017431.2015.1086017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616022PMC
July 2016

Electrocardiographic Tpeak-Tend interval and risk of cardiovascular morbidity and mortality: Results from the Copenhagen ECG study.

Heart Rhythm 2016 Apr 18;13(4):915-24. Epub 2015 Dec 18.

Danish National Research Foundation Centre for Cardiac Arrhythmia (DARC), Copenhagen, Denmark; Laboratory for Molecular Cardiology, The Heart Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2015.12.027DOI Listing
April 2016

pH-dependent inhibition of K₂P3.1 prolongs atrial refractoriness in whole hearts.

Pflugers Arch 2016 Apr 5;468(4):643-54. Epub 2016 Jan 5.

Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.

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http://dx.doi.org/10.1007/s00424-015-1779-0DOI Listing
April 2016

Reply to the Editor--Regarding the Role of Advanced Interatrial Block Pattern as a Predictor of Atrial Fibrillation.

Heart Rhythm 2016 Mar 17;13(3):e87-8. Epub 2015 Nov 17.

Laboratory for Molecular Cardiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.hrthm.2015.11.025DOI Listing
March 2016

P-wave duration and the risk of atrial fibrillation: Results from the Copenhagen ECG Study.

Heart Rhythm 2015 Sep 23;12(9):1887-95. Epub 2015 Apr 23.

Danish National Research Foundation Centre for Cardiac Arrhythmia (DARC), Copenhagen, Denmark; Laboratory for Molecular Cardiology, The Heart Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.hrthm.2015.04.026DOI Listing
September 2015

Comprehensive cardiac rehabilitation improves outcome for patients with implantable cardioverter defibrillator. Findings from the COPE-ICD randomised clinical trial.

Eur J Cardiovasc Nurs 2015 Feb 5;14(1):34-44. Epub 2014 Feb 5.

Danish National Research Foundation Centre for Cardiac Arrhythmia (DARC), University of Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1474515114521920DOI Listing
February 2015

Common and rare variants in SCN10A modulate the risk of atrial fibrillation.

Circ Cardiovasc Genet 2015 Feb;8(1):64-73

From the The Danish National Research Foundation Centre for Cardiac Arrhythmia (DARC), Department of Biomedical Sciences (J.J., M.S.O., L.Y., J.B.N., B.L., N.N., M.G., S.H., A.G.H., J.H.S., T.J.), Laboratory for Molecular Cardiology, Department of Cardiology, Rigshospitalet (J.J., M.S.O., J.B.N., S.H., A.G.H., J.H.S.), and Department of Clinical Medicine (S.H., J.H.S.), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, MA (M.V., P.T.E) and Program in Medical and Population Genetics, The Broad Institute of Harvard and MIT, Cambridge, MA (P.T.E); Department of Medical Research, Bærum Hospital, Vestre Viken Hospital Trust, Rud, Norway (I.E.C.); Department of Cardiology, Copenhagen University Hospital of Bispebjerg, Bispebjerg, Denmark (A.S.); and LuCamp, The Lundbeck Foundation Centre for Applied Medical Genomics in Personalized Disease Prediction, Prevention and Care, Copenhagen, Denmark (S.H.).

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http://dx.doi.org/10.1161/HCG.0000000000000022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392342PMC
February 2015

Brugada syndrome risk loci seem protective against atrial fibrillation.

Eur J Hum Genet 2014 Dec 26;22(12):1357-61. Epub 2014 Mar 26.

1] Danish National Research Foundation Centre for Cardiac Arrhythmia, Copenhagen, Denmark [2] Laboratory for Molecular Cardiology, Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/ejhg.2014.46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231412PMC
December 2014

The diagnostic performance of imaging methods in ARVC using the 2010 Task Force criteria.

Eur Heart J Cardiovasc Imaging 2014 Nov 17;15(11):1219-25. Epub 2014 Jun 17.

Arrhythmia Clinic, Lund University, Skane University Hospital, Getingevagen, 221 85 Lund, Sweden.

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http://dx.doi.org/10.1093/ehjci/jeu109DOI Listing
November 2014

Risk prediction of cardiovascular death based on the QTc interval: evaluating age and gender differences in a large primary care population.

Eur Heart J 2014 May 6;35(20):1335-44. Epub 2014 Mar 6.

Danish National Research Foundation Centre for Cardiac Arrhythmia (DARC), Copenhagen, Denmark Laboratory for Molecular Cardiology, The Heart Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1093/eurheartj/ehu081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028611PMC
May 2014

Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada syndrome mutant.

Am J Physiol Heart Circ Physiol 2014 Apr 21;306(8):H1204-12. Epub 2014 Feb 21.

Danish National Research Foundation Centre for Cardiac Arrhythmia (DARC), Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark;

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http://www.physiology.org/doi/10.1152/ajpheart.00405.2013
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http://dx.doi.org/10.1152/ajpheart.00405.2013DOI Listing
April 2014

Atrial fibrillation: the role of common and rare genetic variants.

Eur J Hum Genet 2014 Mar 10;22(3):297-306. Epub 2013 Jul 10.

1] The Danish National Research Foundation Centre for Cardiac Arrhythmia (DARC), Copenhagen, Denmark [2] Laboratory for Molecular Cardiology, The Heart Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark [3] Department of Surgery and Medicine, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/ejhg.2013.139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925267PMC
March 2014

Very early-onset lone atrial fibrillation patients have a high prevalence of rare variants in genes previously associated with atrial fibrillation.

Heart Rhythm 2014 Feb 18;11(2):246-51. Epub 2013 Oct 18.

Danish National Research Foundation Centre for Cardiac Arrhythmia, Copenhagen, Denmark; Laboratory for Molecular Cardiology, The Heart Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

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https://linkinghub.elsevier.com/retrieve/pii/S15475271130120
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http://dx.doi.org/10.1016/j.hrthm.2013.10.034DOI Listing
February 2014

Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis.

J Mol Cell Cardiol 2014 Feb 27;67:69-76. Epub 2013 Dec 27.

Molecular Cardiology Division, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia; Faculty of Medicine, University of New South Wales, Kensington, New South Wales, Australia; Cardiology Department, St Vincent's Hospital, Darlinghurst, New South Wales, Australia.

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http://dx.doi.org/10.1016/j.yjmcc.2013.12.014DOI Listing
February 2014

Genetic modifier of the QTc interval associated with early-onset atrial fibrillation.

Can J Cardiol 2013 Oct;29(10):1234-40

Danish National Research Foundation Centre for Cardiac Arrhythmia, Copenhagen, Denmark; Laboratory for Molecular Cardiology, Rigshospitalet, Copenhagen, Denmark; The Ion Channel Group, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.cjca.2013.06.009DOI Listing
October 2013

Strain echocardiography improves risk prediction of ventricular arrhythmias after myocardial infarction.

JACC Cardiovasc Imaging 2013 Aug 10;6(8):841-50. Epub 2013 Jul 10.

Department of Cardiology, Institute for Surgical Research and Center for Cardiological Innovation, Oslo University Hospital, Rikshospitalet Oslo, Norway.

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http://dx.doi.org/10.1016/j.jcmg.2013.03.005DOI Listing
August 2013

Cardiac symptoms before sudden cardiac death caused by coronary artery disease: a nationwide study among young Danish people.

Heart 2013 Jul 10;99(13):938-43. Epub 2013 Apr 10.

Danish National Research Foundation Centre for Cardiac Arrhythmia (DARC), University of Copenhagen, Rigshospitalet, Juliane Maries Vej 20, 2100 Copenhagen, Denmark.

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http://dx.doi.org/10.1136/heartjnl-2012-303534DOI Listing
July 2013

Genetic variation in KCNA5: impact on the atrial-specific potassium current IKur in patients with lone atrial fibrillation.

Eur Heart J 2013 May 21;34(20):1517-25. Epub 2012 Dec 21.

Danish National Research Foundation Centre for Cardiac Arrhythmia and Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3, Copenhagen N, Denmark.

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http://dx.doi.org/10.1093/eurheartj/ehs442DOI Listing
May 2013

Rare variants in GJA5 are associated with early-onset lone atrial fibrillation.

Can J Cardiol 2013 Jan 2;29(1):111-6. Epub 2012 Oct 2.

Danish National Research Foundation Centre for Cardiac Arrhythmia, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.cjca.2012.08.002DOI Listing
January 2013

A polymorphism associated with increased levels of YKL-40 and the risk of early onset of lone atrial fibrillation.

J Negat Results Biomed 2013 Jan 2;12. Epub 2013 Jan 2.

Department of Cardiology, The Heart Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1186/1477-5751-12-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554423PMC
January 2013

Genetic loci on chromosomes 4q25, 7p31, and 12p12 are associated with onset of lone atrial fibrillation before the age of 40 years.

Can J Cardiol 2012 Mar-Apr;28(2):191-5. Epub 2012 Feb 14.

The Danish National Research Foundation Centre for Cardiac Arrhythmia, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.cjca.2011.11.016DOI Listing
July 2012

Specificity of elevated intercostal space ECG recording for the type 1 Brugada ECG pattern.

Ann Noninvasive Electrocardiol 2012 Apr;17(2):108-12

The Danish National Research Foundation Centre for Cardiac Arrhythmia, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/j.1542-474X.2012.00499.xDOI Listing
April 2012

Usefulness of immunostaining for plakoglobin as a diagnostic marker of arrhythmogenic right ventricular cardiomyopathy.

Am J Cardiol 2012 Jan 28;109(2):272-5. Epub 2011 Oct 28.

Department of Pathology, Rigshospitalet, Copenhagen University Hospital, Denmark.

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http://dx.doi.org/10.1016/j.amjcard.2011.08.044DOI Listing
January 2012

Common polymorphisms in KCNJ5 [corrected] are associated with early-onset lone atrial fibrillation in Caucasians.

Cardiology 2011 9;118(2):116-20. Epub 2011 May 9.

Danish National Research Foundation Centre for Cardiac Arrhythmia (DARC), Heart Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1159/000323840DOI Listing
December 2011

Association of rs2200733 at 4q25 with early onset of lone atrial fibrillation in young patients.

Scand Cardiovasc J 2011 Dec 27;45(6):324-6. Epub 2011 Jul 27.

Department of Cardiology, The Heart Centre, Rigshospitalet, University of Copenhagen, Denmark.

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http://dx.doi.org/10.3109/14017431.2011.594081DOI Listing
December 2011

Abnormal atrial activation is common in patients with arrhythmogenic right ventricular cardiomyopathy.

J Electrocardiol 2011 Mar-Apr;44(2):237-41. Epub 2010 Nov 20.

Department of Cardiology and Center for Integrative Electrocardiology at Lund University, Lund, Sweden.

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http://linkinghub.elsevier.com/retrieve/pii/S002207361000377
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http://dx.doi.org/10.1016/j.jelectrocard.2010.08.008DOI Listing
July 2011

Screening of KCNN3 in patients with early-onset lone atrial fibrillation.

Europace 2011 Jul 11;13(7):963-7. Epub 2011 Mar 11.

The Danish National Research Foundation Centre for Cardiac Arrhythmia (DARC), University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1093/europace/eur007DOI Listing
July 2011

Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation.

Cardiovasc Res 2011 Mar 4;89(4):786-93. Epub 2010 Nov 4.

Danish National Research Foundation Centre for Cardiac Arrhythmia, Copenhagen, Denmark.

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http://dx.doi.org/10.1093/cvr/cvq348DOI Listing
March 2011

Inflammatory single nucleotide polymorphisms and the risk of atrial fibrillation: a case control study.

Inflamm Res 2011 Mar 4;60(3):209-11. Epub 2010 Dec 4.

Department of Cardiology, The Heart Centre, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100 Copenhagen Ø, Denmark.

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http://dx.doi.org/10.1007/s00011-010-0285-2DOI Listing
March 2011

Abnormal atrial activation in young patients with lone atrial fibrillation.

Europace 2011 Feb 23;13(2):188-92. Epub 2010 Sep 23.

Department of Cardiology, Lund University, SE-221 85 Lund, Sweden.

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http://dx.doi.org/10.1093/europace/euq352DOI Listing
February 2011

Whole-genome amplified DNA from stored dried blood spots is reliable in high resolution melting curve and sequencing analysis.

BMC Med Genet 2011 Feb 9;12:22. Epub 2011 Feb 9.

Dept. of Cardiology, Rigshospitalet and Danish National Research Foundation Centre for Cardiac Arrhythmia (DARC), Copenhagen, Denmark.

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http://dx.doi.org/10.1186/1471-2350-12-22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045282PMC
February 2011

Genetic variation in the inwardly rectifying K channel subunits KCNJ3 (GIRK1) and KCNJ5 (GIRK4) in patients with sinus node dysfunction.

Cardiology 2010 29;115(3):176-81. Epub 2010 Jan 29.

Laboratory of Molecular Cardiology, Copenhagen University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.1159/000279319DOI Listing
July 2010

Making post-mortem implantable cardioverter defibrillator explantation safe.

Europace 2009 Oct;11(10):1317-22

Department of Cardiology, 2013, The Heart Centre, Rigshospitalet, 9 Blegdamsvej, DK-2100 Copenhagen, Denmark.

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http://dx.doi.org/10.1093/europace/eup249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751617PMC
October 2009

Recurrence of pulmonary vein conduction and atrial fibrillation after pulmonary vein isolation for atrial fibrillation: a randomized trial of the ostial versus the extraostial ablation strategy.

Am Heart J 2006 Sep;152(3):537.e1-8

Department of Cardiology, The Heart Centre, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.ahj.2006.05.029DOI Listing
September 2006

Effects of amiodarone and thoracic epidural analgesia on atrial fibrillation after coronary artery bypass grafting.

J Cardiothorac Vasc Anesth 2004 Dec;18(6):709-14

Department of Cardiothoracic Anesthesia, National University Hospital, Rigshopitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1053/j.jvca.2004.08.006DOI Listing
December 2004

Prolonged ischemic heart disease and coronary artery bypass - relation to contractile reserve.

Eur J Cardiothorac Surg 2002 Mar;21(3):417-23

Division of Cardiology, Medical Department B, The Heart Center, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/s1010-7940(01)01138-1DOI Listing
March 2002