Jerry E Chipuk

Jerry E Chipuk

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Jerry E Chipuk

Publications by authors named "Jerry E Chipuk"

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Single-Cell and Population-Level Analyses Using Real-Time Kinetic Labeling Couples Proliferation and Cell Death Mechanisms.

Dev Cell 2019 Sep 25. Epub 2019 Sep 25.

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1130, New York, NY 10029, USA; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA; Department of Dermatology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA; Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2019.08.016DOI Listing
September 2019

Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool.

Cell 2019 Aug;178(5):1102-1114.e17

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, USA; The Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, USA; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.07.050DOI Listing
August 2019

Mitochondrial origins of fractional control in regulated cell death.

Nat Commun 2019 03 21;10(1):1313. Epub 2019 Mar 21.

IBM T.J. Watson Research Center, 1101 Kitchawan Road, Yorktown Heights, NY, 10598, USA.

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http://dx.doi.org/10.1038/s41467-019-09275-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428895PMC
March 2019

Late-onset megaconial myopathy in mice lacking group I Paks.

Skelet Muscle 2019 02 21;9(1). Epub 2019 Feb 21.

Department of Cell, Developmental, and Regenerative Biology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1020, New York, NY, 10029, USA.

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http://dx.doi.org/10.1186/s13395-019-0191-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383276PMC
February 2019

FBXW7 regulates a mitochondrial transcription program by modulating MITF.

Pigment Cell Melanoma Res 2018 09 29;31(5):636-640. Epub 2018 Apr 29.

Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1111/pcmr.12704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192859PMC
September 2018

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Authors:
Lorenzo Galluzzi Ilio Vitale Stuart A Aaronson John M Abrams Dieter Adam Patrizia Agostinis Emad S Alnemri Lucia Altucci Ivano Amelio David W Andrews Margherita Annicchiarico-Petruzzelli Alexey V Antonov Eli Arama Eric H Baehrecke Nickolai A Barlev Nicolas G Bazan Francesca Bernassola Mathieu J M Bertrand Katiuscia Bianchi Mikhail V Blagosklonny Klas Blomgren Christoph Borner Patricia Boya Catherine Brenner Michelangelo Campanella Eleonora Candi Didac Carmona-Gutierrez Francesco Cecconi Francis K-M Chan Navdeep S Chandel Emily H Cheng Jerry E Chipuk John A Cidlowski Aaron Ciechanover Gerald M Cohen Marcus Conrad Juan R Cubillos-Ruiz Peter E Czabotar Vincenzo D'Angiolella Ted M Dawson Valina L Dawson Vincenzo De Laurenzi Ruggero De Maria Klaus-Michael Debatin Ralph J DeBerardinis Mohanish Deshmukh Nicola Di Daniele Francesco Di Virgilio Vishva M Dixit Scott J Dixon Colin S Duckett Brian D Dynlacht Wafik S El-Deiry John W Elrod Gian Maria Fimia Simone Fulda Ana J García-Sáez Abhishek D Garg Carmen Garrido Evripidis Gavathiotis Pierre Golstein Eyal Gottlieb Douglas R Green Lloyd A Greene Hinrich Gronemeyer Atan Gross Gyorgy Hajnoczky J Marie Hardwick Isaac S Harris Michael O Hengartner Claudio Hetz Hidenori Ichijo Marja Jäättelä Bertrand Joseph Philipp J Jost Philippe P Juin William J Kaiser Michael Karin Thomas Kaufmann Oliver Kepp Adi Kimchi Richard N Kitsis Daniel J Klionsky Richard A Knight Sharad Kumar Sam W Lee John J Lemasters Beth Levine Andreas Linkermann Stuart A Lipton Richard A Lockshin Carlos López-Otín Scott W Lowe Tom Luedde Enrico Lugli Marion MacFarlane Frank Madeo Michal Malewicz Walter Malorni Gwenola Manic Jean-Christophe Marine Seamus J Martin Jean-Claude Martinou Jan Paul Medema Patrick Mehlen Pascal Meier Sonia Melino Edward A Miao Jeffery D Molkentin Ute M Moll Cristina Muñoz-Pinedo Shigekazu Nagata Gabriel Nuñez Andrew Oberst Moshe Oren Michael Overholtzer Michele Pagano Theocharis Panaretakis Manolis Pasparakis Josef M Penninger David M Pereira Shazib Pervaiz Marcus E Peter Mauro Piacentini Paolo Pinton Jochen H M Prehn Hamsa Puthalakath Gabriel A Rabinovich Markus Rehm Rosario Rizzuto Cecilia M P Rodrigues David C Rubinsztein Thomas Rudel Kevin M Ryan Emre Sayan Luca Scorrano Feng Shao Yufang Shi John Silke Hans-Uwe Simon Antonella Sistigu Brent R Stockwell Andreas Strasser Gyorgy Szabadkai Stephen W G Tait Daolin Tang Nektarios Tavernarakis Andrew Thorburn Yoshihide Tsujimoto Boris Turk Tom Vanden Berghe Peter Vandenabeele Matthew G Vander Heiden Andreas Villunger Herbert W Virgin Karen H Vousden Domagoj Vucic Erwin F Wagner Henning Walczak David Wallach Ying Wang James A Wells Will Wood Junying Yuan Zahra Zakeri Boris Zhivotovsky Laurence Zitvogel Gerry Melino Guido Kroemer

Cell Death Differ 2018 03 23;25(3):486-541. Epub 2018 Jan 23.

Paris Descartes/Paris V University, Paris, France.

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http://dx.doi.org/10.1038/s41418-017-0012-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864239PMC
March 2018

Mitochondrial Fission in Human Diseases.

Handb Exp Pharmacol 2017 ;240:159-188

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy PLC, New York, NY, 10029, USA.

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http://link.springer.com/10.1007/164_2016_38
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http://dx.doi.org/10.1007/164_2016_38DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388405PMC
December 2017

Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells.

Nature 2017 06 24;546(7656):158-161. Epub 2017 May 24.

Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, New York 10016, USA.

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http://dx.doi.org/10.1038/nature22352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683179PMC
June 2017

Mouse Liver Mitochondria Isolation, Size Fractionation, and Real-time MOMP Measurement.

Bio Protoc 2016 Aug;6(15)

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, USA; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, USA; The Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, USA; Department of Dermatology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, USA; The Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, USA.

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http://dx.doi.org/10.21769/BioProtoc.1892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234469PMC
August 2016

The deadly landscape of pro-apoptotic BCL-2 proteins in the outer mitochondrial membrane.

FEBS J 2016 07 6;283(14):2676-89. Epub 2016 Jan 6.

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1111/febs.13624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907887PMC
July 2016

Special Issue on Cell Death: Murder, mystery (and a little bit of mayhem) in Manhattan.

FEBS J 2016 07;283(14):2565-7

Molecular Cell Biology Laboratory, Department of Genetics, The Smurfit Institute, Trinity College, Dublin 2, Ireland.

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http://dx.doi.org/10.1111/febs.13782DOI Listing
July 2016

Activation of the Mitochondrial Fragmentation Protein DRP1 Correlates with BRAF(V600E) Melanoma.

J Invest Dermatol 2015 Oct 1;135(10):2544-2547. Epub 2015 Jun 1.

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA; Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York, USA; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA; The Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA; The Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA. Electronic address:

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http://dx.doi.org/10.1038/jid.2015.196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567922PMC
October 2015

Pin1-Induced Proline Isomerization in Cytosolic p53 Mediates BAX Activation and Apoptosis.

Mol Cell 2015 Aug 30;59(4):677-84. Epub 2015 Jul 30.

Department of Structural Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA; Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Sciences Center, 920 Court Avenue, Memphis, TN 38163, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2015.06.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546541PMC
August 2015

Mitochondrial division is requisite to RAS-induced transformation and targeted by oncogenic MAPK pathway inhibitors.

Mol Cell 2015 Feb;57(3):521-36

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, USA; Department of Dermatology, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, USA; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, USA; The Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, USA; The Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2015.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320323PMC
February 2015

Mitochondrial shape governs BAX-induced membrane permeabilization and apoptosis.

Mol Cell 2015 Jan 4;57(1):69-82. Epub 2014 Dec 4.

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA; The Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA; The Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA; Department of Dermatology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2014.10.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289414PMC
January 2015

Putting the pieces together: How is the mitochondrial pathway of apoptosis regulated in cancer and chemotherapy?

Cancer Metab 2014 6;2:16. Epub 2014 Oct 6.

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, 1425 Madison Avenue, Box 1130, New York, NY 10029, USA.

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http://dx.doi.org/10.1186/2049-3002-2-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304082PMC
January 2015

B cell lymphoma-2 (BCL-2) homology domain 3 (BH3) mimetics demonstrate differential activities dependent upon the functional repertoire of pro- and anti-apoptotic BCL-2 family proteins.

J Biol Chem 2014 Sep 5;289(38):26481-91. Epub 2014 Aug 5.

From the Departments of Oncological Sciences and The Tisch Cancer Institute, The Graduate School of Biomedical Sciences, and Dermatology, The Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029

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http://dx.doi.org/10.1074/jbc.M114.569632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176207PMC
September 2014

Preclinical pharmacological evaluation of a novel multiple kinase inhibitor, ON123300, in brain tumor models.

Mol Cancer Ther 2014 May 25;13(5):1105-16. Epub 2014 Feb 25.

Authors' Affiliations: Departments of Pharmacology and Systems Therapeutics and Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York; and Department of Pharmaceutical Science, University of South Florida, Tampa, Florida.

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http://dx.doi.org/10.1158/1535-7163.MCT-13-0847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013241PMC
May 2014

Inducible nitric oxide synthase drives mTOR pathway activation and proliferation of human melanoma by reversible nitrosylation of TSC2.

Cancer Res 2014 Feb 7;74(4):1067-78. Epub 2014 Jan 7.

Authors' Affiliations: Departments of Otolaryngology, Dermatology, Immunology, and Oncological Sciences; Division of Hematology and Oncology, Department of Medicine, Department of Otolaryngology, The Tisch Cancer Institute, Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai; The Tisch Cancer Institute; Department of Genetics and Genomic Sciences, One Gustave L. Levy Place, New York, New York; and Departments of Melanoma Medical Oncology and Biostatistics, University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-0588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960077PMC
February 2014

Death upon a kiss: mitochondrial outer membrane composition and organelle communication govern sensitivity to BAK/BAX-dependent apoptosis.

Chem Biol 2014 Jan 21;21(1):114-23. Epub 2013 Nov 21.

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1130, New York, NY 10029, USA; Department of Dermatology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1130, New York, NY 10029, USA; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1130, New York, NY 10029, USA; The Metabolism Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1130, New York, NY 10029, USA; The Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1130, New York, NY 10029, USA. Electronic address:

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http://ac.els-cdn.com/S1074552113003839/1-s2.0-S107455211300
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http://linkinghub.elsevier.com/retrieve/pii/S107455211300383
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http://dx.doi.org/10.1016/j.chembiol.2013.10.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947007PMC
January 2014

How do I kill thee? Let me count the ways: p53 regulates PARP-1 dependent necrosis.

Bioessays 2014 Jan 24;36(1):46-51. Epub 2013 Oct 24.

Icahn School of Medicine at Mount Sinai, Department of Oncological Sciences, New York, NY, USA; Icahn School of Medicine at Mount Sinai, The Tisch Cancer Institute, New York, NY, USA; Icahn School of Medicine at Mount Sinai, The Graduate School of Biomedical Sciences, New York, NY, USA.

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http://dx.doi.org/10.1002/bies.201300117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914234PMC
January 2014

BAK/BAX activation and cytochrome c release assays using isolated mitochondria.

Methods 2013 Jun 6;61(2):146-55. Epub 2013 Apr 6.

Icahn School of Medicine at Mount Sinai, Department of Oncological Sciences, One Gustave L. Levy Place, Box 1130, New York, NY 10029, USA.

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http://dx.doi.org/10.1016/j.ymeth.2013.03.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686896PMC
June 2013

BAK activation is necessary and sufficient to drive ceramide synthase-dependent ceramide accumulation following inhibition of BCL2-like proteins.

Biochem J 2013 May;452(1):111-9

Division of Hematology and Oncology, Department of Medicine, James Graham Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA.

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http://dx.doi.org/10.1042/BJ20130147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642864PMC
May 2013

Getting away with murder: how does the BCL-2 family of proteins kill with immunity?

Ann N Y Acad Sci 2013 May 25;1285:59-79. Epub 2013 Mar 25.

Department of Oncological Sciences, Mount Sinai School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1111/nyas.12045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663908PMC
May 2013

Survival of HER2-Positive Breast Cancer Cells: Receptor Signaling to Apoptotic Control Centers.

Genes Cancer 2013 May;4(5-6):187-95

Department of Biomedical Sciences, Long Island University Post, Brookville, NY, USA.

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http://dx.doi.org/10.1177/1947601913488598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782004PMC
May 2013

Inter-organellar communication with mitochondria regulates both the intrinsic and extrinsic pathways of apoptosis.

Commun Integr Biol 2013 Mar;6(2):e22872

Department of Oncological Sciences; Mount Sinai School of Medicine; New York, NY USA ; The Tisch Cancer Institute; New York, NY USA.

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http://dx.doi.org/10.4161/cib.22872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609836PMC
March 2013

Examining BCL-2 family function with large unilamellar vesicles.

J Vis Exp 2012 Oct 5(68). Epub 2012 Oct 5.

Department of Oncological Sciences, Department of Dermatology, The Tisch Cancer Institute, The Graduate School of Biological Sciences, Mount Sinai School of Medicine.

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http://dx.doi.org/10.3791/4291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490295PMC
October 2012

Born to be alive: a role for the BCL-2 family in melanoma tumor cell survival, apoptosis, and treatment.

Front Oncol 2011 Oct;1(34)

Department of Oncological Sciences, Mount Sinai School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.3389/fonc.2011.00034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260552PMC
October 2011

The Role of BH3-Only Proteins in Tumor Cell Development, Signaling, and Treatment.

Genes Cancer 2011 May;2(5):523-37

Department of Oncological Sciences, Mount Sinai School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1177/1947601911417177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161420PMC
May 2011

BH3 domains other than Bim and Bid can directly activate Bax/Bak.

J Biol Chem 2011 Jan 1;286(1):491-501. Epub 2010 Nov 1.

Department of Pathology, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.1074/jbc.M110.167148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013008PMC
January 2011

PB1-F2 proteins from H5N1 and 20 century pandemic influenza viruses cause immunopathology.

PLoS Pathog 2010 Jul 22;6(7):e1001014. Epub 2010 Jul 22.

Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.

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http://dx.plos.org/10.1371/journal.ppat.1001014
Publisher Site
http://dx.doi.org/10.1371/journal.ppat.1001014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908617PMC
July 2010

The BCL-2 family reunion.

Mol Cell 2010 Feb;37(3):299-310

Department of Immunology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1016/j.molcel.2010.01.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222298PMC
February 2010

PUMA cooperates with direct activator proteins to promote mitochondrial outer membrane permeabilization and apoptosis.

Cell Cycle 2009 Sep 2;8(17):2692-6. Epub 2009 Sep 2.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228357PMC
http://dx.doi.org/10.4161/cc.8.17.9412DOI Listing
September 2009

Mitochondrial outer membrane proteins assist Bid in Bax-mediated lipidic pore formation.

Mol Biol Cell 2009 Apr 25;20(8):2276-85. Epub 2009 Feb 25.

Department of Pathology, University of Iowa Carver College of Medicine, Iowa City, 52242, USA.

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http://dx.doi.org/10.1091/mbc.e08-10-1056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669034PMC
April 2009

Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins.

Proc Natl Acad Sci U S A 2008 Dec 12;105(51):20327-32. Epub 2008 Dec 12.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1073/pnas.0808036105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629294PMC
December 2008

Apoptosis: Stabbed in the BAX.

Nature 2008 Oct;455(7216):1047-9

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http://dx.doi.org/10.1038/4551047aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242476PMC
October 2008

How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

Trends Cell Biol 2008 Apr 7;18(4):157-64. Epub 2008 Mar 7.

St Jude Children's Research Hospital, 332 North Lauderdale Street, Memphis, TN 38105, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S096289240800066
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http://dx.doi.org/10.1016/j.tcb.2008.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242477PMC
April 2008

p53 and metabolism: Inside the TIGAR.

Cell 2006 Jul;126(1):30-2

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1016/j.cell.2006.06.032DOI Listing
July 2006

PUMA couples the nuclear and cytoplasmic proapoptotic function of p53.

Science 2005 Sep;309(5741):1732-5

Division of Cellular Immunology, La Jolla Institute for Allergy and Immunology, 10355 Science Center Drive, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1126/science.1114297DOI Listing
September 2005

Cytoplasmic p53: bax and forward.

Cell Cycle 2004 Apr 1;3(4):429-31. Epub 2004 Apr 1.

La Jolla Institute for Allergy and Immunology, Division of Cellular Immunology, San Diego, California 92121, USA.

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April 2004

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis.

Science 2004 Feb;303(5660):1010-4

Division of Cellular Immunology, La Jolla Institute for Allergy and Immunology, 10355 Science Center Drive, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1126/science.1092734DOI Listing
February 2004

Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription.

Cancer Cell 2003 Nov;4(5):371-81

Division of Cellular Immunology, La Jolla Institute for Allergy and Immunology, San Diego, CA 92121, USA.

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November 2003

p53's believe it or not: lessons on transcription-independent death.

J Clin Immunol 2003 Sep;23(5):355-61

Division of Cellular Immunology, La Jolla Institute for Allergy and Immunology, 10355 Science Center Drive, San Diego, California 92121, USA.

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http://dx.doi.org/10.1023/a:1025365432325DOI Listing
September 2003

p53's believe it or not: lessons on transcription-independent death.

J Clin Immunol 2003 Sep;23(5):355-61

Division of Cellular Immunology, La Jolla Institute for Allergy and Immunology, 10355 Science Center Drive, San Diego, California 92121, USA.

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http://dx.doi.org/10.1023/a:1025365432325DOI Listing
September 2003

The androgen receptor represses transforming growth factor-beta signaling through interaction with Smad3.

J Biol Chem 2002 Jan 13;277(2):1240-8. Epub 2001 Nov 13.

Ireland Cancer Center Research Laboratories, Department of Pharmacology, Case Western Reserve University/University Hospitals of Cleveland, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1074/jbc.M108855200DOI Listing
January 2002