Jerrold R Turner

Jerrold R Turner

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Jerrold R Turner

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Differential regulation of claudin-2 and claudin-15 expression in children and adults with malabsorptive disease.

Lab Invest 2020 Mar 11;100(3):483-490. Epub 2019 Oct 11.

Laboratory of Mucosal Barrier Pathobiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41374-019-0324-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047618PMC
March 2020

Cumulative Histologic Inflammation Predicts Colorectal Neoplasia in Ulcerative Colitis: A Validation Study.

Inflamm Bowel Dis 2020 Mar 10. Epub 2020 Mar 10.

Inflammatory Bowel Disease Center, University of Chicago Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1093/ibd/izaa047DOI Listing
March 2020

Contributions of Myosin Light Chain Kinase to Regulation of Epithelial Paracellular Permeability and Mucosal Homeostasis.

Int J Mol Sci 2020 Feb 3;21(3). Epub 2020 Feb 3.

Laboratory of Mucosal Barrier Pathobiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.3390/ijms21030993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037368PMC
February 2020

Cadmium ingestion exacerbates Salmonella infection, with a loss of goblet cells through activation of Notch signaling pathways by ROS in the intestine.

J Hazard Mater 2020 Feb 9;391:122262. Epub 2020 Feb 9.

MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Weigang 1, Nanjing, Jiangsu, 210095, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.jhazmat.2020.122262DOI Listing
February 2020

Rigor, Reproducibility, and Responsibility: A Quantum of Solace.

Authors:
Jerrold R Turner

Cell Mol Gastroenterol Hepatol 2019 9;7(4):869-871. Epub 2019 Apr 9.

Brigham and Women's Hospital and Harvard Medical School. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S2352345X193003
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http://dx.doi.org/10.1016/j.jcmgh.2019.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522661PMC
January 2020

Quantification of Proliferative and Dead Cells in Enteroids.

J Vis Exp 2020 Jan 31(155). Epub 2020 Jan 31.

Jiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Suda (CAM-SU) Genomic Resource Center, Medical College of Soochow University, Department of Oncology, The First Affiliated Hospital of Soochow University;

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http://dx.doi.org/10.3791/60501DOI Listing
January 2020

Histologic Healing Is More Strongly Associated with Clinical Outcomes in Ileal Crohn's Disease than Endoscopic Healing.

Clin Gastroenterol Hepatol 2019 Dec 5. Epub 2019 Dec 5.

Inflammatory Bowel Disease Center, University of Chicago Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1016/j.cgh.2019.11.056DOI Listing
December 2019

Inflammation-induced Occludin Downregulation Limits Epithelial Apoptosis by Suppressing Caspase-3 Expression.

Gastroenterology 2019 11 8;157(5):1323-1337. Epub 2019 Aug 8.

Laboratory of Mucosal Barrier Pathobiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; Department of Pathology, The University of Chicago, Chicago, Illinois. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.07.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815722PMC
November 2019

Slowed gastric emptying and improved oral glucose tolerance produced by a nanomolar-potency inhibitor of calcium-activated chloride channel TMEM16A.

FASEB J 2019 Oct 12;33(10):11247-11257. Epub 2019 Jul 12.

Department of Medicine and Physiology, University of California, San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1096/fj.201900858RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766656PMC
October 2019

Reducing IRF5 expression attenuates colitis in mice, but impairs the clearance of intestinal pathogens.

Mucosal Immunol 2019 07 3;12(4):874-887. Epub 2019 May 3.

Department of Internal Medicine, Yale University, New Haven, CT, 06510, USA.

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http://www.nature.com/articles/s41385-019-0165-1
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http://dx.doi.org/10.1038/s41385-019-0165-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688861PMC
July 2019

Correction to: Reducing IRF5 expression attenuates colitis in mice, but impairs the clearance of intestinal pathogens.

Mucosal Immunol 2019 Jul;12(4):1065

Department of Internal Medicine, Yale University, New Haven, CT, 06510, USA.

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http://dx.doi.org/10.1038/s41385-019-0179-8DOI Listing
July 2019

cAMP Stimulates SLC26A3 Activity in Human Colon by a CFTR-Dependent Mechanism That Does Not Require CFTR Activity.

Cell Mol Gastroenterol Hepatol 2019 17;7(3):641-653. Epub 2019 Jan 17.

Department of Medicine, Division of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.jcmgh.2019.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438990PMC
June 2019

Occludin knockdown is not sufficient to induce transepithelial macromolecule passage.

Tissue Barriers 2019 4;7(2):1612661. Epub 2019 Jun 4.

e Institute of Biochemistry II , Jena University Hospital , Jena , Germany.

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http://dx.doi.org/10.1080/21688370.2019.1608759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619991PMC
June 2019

Interleukin 22 Expands Transit-Amplifying Cells While Depleting Lgr5 Stem Cells via Inhibition of Wnt and Notch Signaling.

Cell Mol Gastroenterol Hepatol 2019 18;7(2):255-274. Epub 2018 Sep 18.

Jiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Suda (CAM-SU) Genome Resource Center, Soochow University, and Department of Oncology, First Affiliated Hospital of Soochow University, Suzhou, China; Department of Pathology, University of Chicago, Chicago, Illinois. Electronic address:

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http://dx.doi.org/10.1016/j.jcmgh.2018.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352747PMC
May 2019

On the Genesis of CMGH.

Authors:
Jerrold R Turner

Cell Mol Gastroenterol Hepatol 2019 10;8(1):143-144. Epub 2019 May 10.

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http://dx.doi.org/10.1016/j.jcmgh.2019.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599096PMC
May 2019

An intestinal paracellular pathway biased toward positively-charged macromolecules.

J Control Release 2018 10 6;288:111-125. Epub 2018 Sep 6.

Department of Pharmacy and Pharmacology, University of Bath, Bath BA2 7AY, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2018.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219475PMC
October 2018

Cell injury triggers actin polymerization to initiate epithelial restitution.

J Cell Sci 2018 08 20;131(16). Epub 2018 Aug 20.

Department of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, OH 45267, USA

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http://dx.doi.org/10.1242/jcs.216317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127731PMC
August 2018

Epithelial IL-15 Is a Critical Regulator of γδ Intraepithelial Lymphocyte Motility within the Intestinal Mucosa.

J Immunol 2018 07 8;201(2):747-756. Epub 2018 Jun 8.

Department of Pathology and Laboratory Medicine, Center for Immunity and Inflammation, Rutgers New Jersey Medical School, Newark, NJ 07103;

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http://dx.doi.org/10.4049/jimmunol.1701603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075741PMC
July 2018

An algorithm for the classification of mRNA patterns in eosinophilic esophagitis: Integration of machine learning.

J Allergy Clin Immunol 2018 04 19;141(4):1354-1364.e9. Epub 2017 Dec 19.

Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, Mass; Department of Medicine, Harvard Medical School, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.11.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425755PMC
April 2018

Listeria Adhesion Protein Induces Intestinal Epithelial Barrier Dysfunction for Bacterial Translocation.

Cell Host Microbe 2018 04 5;23(4):470-484.e7. Epub 2018 Apr 5.

Molecular Food Microbiology Laboratory, Department of Food Science, Purdue University, West Lafayette, IN 47907, USA; Department of Comparative Pathobiology, Purdue University, West Lafayette, IN 47907, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19313128183013
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http://dx.doi.org/10.1016/j.chom.2018.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750208PMC
April 2018

Attaching-and-Effacing Pathogens Exploit Junction Regulatory Activities of N-WASP and SNX9 to Disrupt the Intestinal Barrier.

Cell Mol Gastroenterol Hepatol 2018 Mar 15;5(3):273-288. Epub 2017 Dec 15.

Division of Gastroenterology/Nutrition and Center for Inflammatory Bowel Disease Treatment and Research, Boston Children's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jcmgh.2017.11.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904039PMC
March 2018

State of the Journal: CMGH's Progress, Prospects, and Impact Factor.

Gastroenterology 2018 Feb;154(3):460-461

Cellular and Molecular Gastroenterology and Hepatology.

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http://dx.doi.org/10.1053/j.gastro.2018.01.008DOI Listing
February 2018

Mesenteric Adipose-derived Stromal Cells From Crohn's Disease Patients Induce Protective Effects in Colonic Epithelial Cells and Mice With Colitis.

Cell Mol Gastroenterol Hepatol 2018 8;6(1):1-16. Epub 2018 Feb 8.

Center for Inflammatory Bowel Diseases, Division of Digestive Diseases, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California.

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http://dx.doi.org/10.1016/j.jcmgh.2018.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008259PMC
February 2018

Cell Biology of Tight Junction Barrier Regulation and Mucosal Disease.

Cold Spring Harb Perspect Biol 2018 01 2;10(1). Epub 2018 Jan 2.

Departments of Pathology and Medicine (Gastroenterology), Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115.

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http://dx.doi.org/10.1101/cshperspect.a029314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749156PMC
January 2018

State of the Journal: 's Progress, Prospects, and Impact Factor.

Cell Mol Gastroenterol Hepatol 2018 18;5(2):157-158. Epub 2017 Dec 18.

Cellular and Molecular Gastroenterology and Hepatology.

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http://dx.doi.org/10.1016/j.jcmgh.2017.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904048PMC
December 2017

Histologic Normalization Occurs in Ulcerative Colitis and Is Associated With Improved Clinical Outcomes.

Clin Gastroenterol Hepatol 2017 Oct 24;15(10):1557-1564.e1. Epub 2017 Feb 24.

Inflammatory Bowel Disease Center, University of Chicago Medicine, Chicago, Illinois. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2017.02.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618439PMC
October 2017

Contributions of intestinal epithelial barriers to health and disease.

Exp Cell Res 2017 09 23;358(1):71-77. Epub 2017 Mar 23.

Departments of Pathology and Medicine (Division of Gastroenterology, Hepatology, and Endoscopy), Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2017.03.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958612PMC
September 2017

Epithelial Organization: The Gut and Beyond.

Compr Physiol 2017 Sep 12;7(4):1497-1518. Epub 2017 Sep 12.

Division of Gastroenterology, Hepatology, and Endoscopy, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/cphy.c170003DOI Listing
September 2017

Impaired Barrier Function and Autoantibody Generation in Malnutrition Enteropathy in Zambia.

EBioMedicine 2017 Aug 19;22:191-199. Epub 2017 Jul 19.

Tropical Gastroenterology and Nutrition Group, University of Zambia School of Medicine, Nationalist Road, Lusaka, Zambia; Blizard Institute, Barts & The London School of Medicine, Queen Mary University of London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552244PMC
August 2017

Dynamic modeling of the tight junction pore pathway.

Ann N Y Acad Sci 2017 06 12;1397(1):209-218. Epub 2017 Jun 12.

Department of Pathology, The University of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1111/nyas.13374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488723PMC
June 2017

IL-22 Upregulates Epithelial Claudin-2 to Drive Diarrhea and Enteric Pathogen Clearance.

Cell Host Microbe 2017 Jun;21(6):671-681.e4

Department of Pathology, The University of Chicago, 5841 South Maryland, Chicago, IL 60637, USA; Departments of Pathology and Medicine (Gastroenterology), Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2017.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541253PMC
June 2017

Neisseria gonorrhoeae infects the human endocervix by activating non-muscle myosin II-mediated epithelial exfoliation.

PLoS Pathog 2017 Apr 13;13(4):e1006269. Epub 2017 Apr 13.

Department of Cell Biology & Molecular Genetics, University of Maryland, College Park, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1006269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391109PMC
April 2017

The Awards.

Authors:
Jerrold R Turner

Cell Mol Gastroenterol Hepatol 2017 Mar 3;3(2):129-130. Epub 2017 Feb 3.

Cellular and Molecular Gastroenterology and Hepatology.

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http://dx.doi.org/10.1016/j.jcmgh.2017.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331835PMC
March 2017

A Role for cAMP and Protein Kinase A in Experimental Necrotizing Enterocolitis.

Am J Pathol 2017 Feb 8;187(2):401-417. Epub 2016 Dec 8.

Division of Pediatric Surgery, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois; Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2016.10.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389366PMC
February 2017

The intestinal epithelial barrier: a therapeutic target?

Nat Rev Gastroenterol Hepatol 2017 Jan 16;14(1):9-21. Epub 2016 Nov 16.

Department of Pathology, The University of Chicago, 5841 South Maryland, Chicago, Illinois 60637, USA.

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http://www.nature.com/articles/nrgastro.2016.169
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http://dx.doi.org/10.1038/nrgastro.2016.169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554468PMC
January 2017

The mucosal barrier at a glance.

J Cell Sci 2017 01 6;130(2):307-314. Epub 2017 Jan 6.

Department of Medicine (Gastroenterology, Hepatology, and Endoscopy), Brigham and Women's Hospital and Harvard Medical School, 20 Shattuck St, TH1428, Boston, MA 02115, USA

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http://dx.doi.org/10.1242/jcs.193482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278669PMC
January 2017

A Picture Is Worth a Thousand Words.

Authors:
Jerrold R Turner

Cell Mol Gastroenterol Hepatol 2017 Jan 8;3(1). Epub 2016 Dec 8.

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https://linkinghub.elsevier.com/retrieve/pii/S2352345X163013
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http://dx.doi.org/10.1016/j.jcmgh.2016.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247416PMC
January 2017

The serine protease-mediated increase in intestinal epithelial barrier function is dependent on occludin and requires an intact tight junction.

Am J Physiol Gastrointest Liver Physiol 2016 09 4;311(3):G466-79. Epub 2016 Aug 4.

Department of Physiology and Pharmacology and Calvin, Phoebe and Joan Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; and

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http://dx.doi.org/10.1152/ajpgi.00441.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076006PMC
September 2016

PubMed, PubMed Central, and Impact Factor.

Authors:
Jerrold R Turner

Cell Mol Gastroenterol Hepatol 2016 Sep 9;2(5):537. Epub 2016 Sep 9.

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http://dx.doi.org/10.1016/j.jcmgh.2016.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042885PMC
September 2016

Not All Mice Are the Same: Standardization of Animal Research Data Presentation.

Gastroenterology 2016 06 8;150(7):1503-1504. Epub 2016 Apr 8.

Cellular and Molecular Gastroenterology and Hepatology.

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http://dx.doi.org/10.1053/j.gastro.2016.03.034DOI Listing
June 2016

Beyond Ussing's chambers: contemporary thoughts on integration of transepithelial transport.

Am J Physiol Cell Physiol 2016 Mar 23;310(6):C423-31. Epub 2015 Dec 23.

Department of Pathology, The University of Chicago, Chicago, Illinois; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts; and Department of Medicine, Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, Boston, Massachusetts

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http://dx.doi.org/10.1152/ajpcell.00348.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796286PMC
March 2016

Looking Back; Looking Forward!

Authors:
Jerrold R Turner

Cell Mol Gastroenterol Hepatol 2016 Jan 26;2(1). Epub 2015 Nov 26.

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https://linkinghub.elsevier.com/retrieve/pii/S2352345X150017
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http://dx.doi.org/10.1016/j.jcmgh.2015.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980711PMC
January 2016

Is Growing!

Authors:
Jerrold R Turner

Cell Mol Gastroenterol Hepatol 2015 Sep 15;1(5):453. Epub 2015 Aug 15.

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http://dx.doi.org/10.1016/j.jcmgh.2015.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301405PMC
September 2015

Prion protein functions as a ferrireductase partner for ZIP14 and DMT1.

Free Radic Biol Med 2015 Jul 8;84:322-330. Epub 2015 Apr 8.

Department of Pathology, Case Western Reserve University/University Hospitals Case Medical Center, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1016/j.freeradbiomed.2015.03.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476631PMC
July 2015

Substance P mediates pro-inflammatory cytokine release form mesenteric adipocytes in Inflammatory Bowel Disease patients.

Cell Mol Gastroenterol Hepatol 2015 Jul;1(4):420-432

Inflammatory Bowel Disease Center, and Neuroendocrine Assay Core, Division of Digestive Diseases, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1016/j.jcmgh.2015.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629258PMC
July 2015

γδ Intraepithelial Lymphocyte Migration Limits Transepithelial Pathogen Invasion and Systemic Disease in Mice.

Gastroenterology 2015 Jun 4;148(7):1417-26. Epub 2015 Mar 4.

Department of Pathology, The University of Chicago, Chicago, Illinois; Department of Medicine, The University of Chicago, Chicago, Illinois. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2015.02.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685713PMC
June 2015

Conceptual barriers to understanding physical barriers.

Semin Cell Dev Biol 2015 Jun 21;42:13-21. Epub 2015 May 21.

Department of Pathology, The University of Chicago, United States. Electronic address:

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http://dx.doi.org/10.1016/j.semcdb.2015.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562871PMC
June 2015

Synergistic Action of Staphylococcus aureus α-Toxin on Platelets and Myeloid Lineage Cells Contributes to Lethal Sepsis.

Cell Host Microbe 2015 Jun;17(6):775-87

Department of Microbiology, University of Chicago, Chicago, IL 60637, USA; Department of Pediatrics, University of Chicago, Chicago, IL 60637, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2015.05.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642999PMC
June 2015

Effects of obesity on severity of colitis and cytokine expression in mouse mesenteric fat. Potential role of adiponectin receptor 1.

Am J Physiol Gastrointest Liver Physiol 2015 Apr 15;308(7):G591-604. Epub 2015 Jan 15.

Inflammatory Bowel Disease Center, and Neuroendocrine Assay Core, Division of Digestive Diseases, David Geffen School of Medicine at UCLA, Los Angeles, California;

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http://dx.doi.org/10.1152/ajpgi.00269.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385897PMC
April 2015

Expression of human decay-accelerating factor on intestinal epithelium of transgenic mice does not facilitate infection by the enteral route.

J Virol 2015 Apr 4;89(8):4311-8. Epub 2015 Feb 4.

Division of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA

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http://dx.doi.org/10.1128/JVI.03468-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442383PMC
April 2015

Dysbiosis-induced intestinal inflammation activates tumor necrosis factor receptor I and mediates alcoholic liver disease in mice.

Hepatology 2015 Mar 30;61(3):883-94. Epub 2015 Jan 30.

Department of Medicine, University of California San Diego, La Jolla, CA.

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http://dx.doi.org/10.1002/hep.27489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340725PMC
March 2015

A Journey of a Thousand Miles Begins With a Single Step, and Then Another . . .

Authors:
Jerrold R Turner

Cell Mol Gastroenterol Hepatol 2015 Mar 4;1(2):121-122. Epub 2015 Feb 4.

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http://dx.doi.org/10.1016/j.jcmgh.2015.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301140PMC
March 2015

: The Revolution Starts Now.

Cell Mol Gastroenterol Hepatol 2015 Jan 10;1(1). Epub 2015 Jan 10.

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http://dx.doi.org/10.1016/j.jcmgh.2014.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301188PMC
January 2015

Overactivation of intestinal SREBP2 in mice increases serum cholesterol.

PLoS One 2014 20;9(1):e84221. Epub 2014 Jan 20.

Research and Development, Jesse Brown VA Medical Center, Chicago, Illinois, United States of America ; Division of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0084221PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896331PMC
December 2014

The role of molecular remodeling in differential regulation of tight junction permeability.

Semin Cell Dev Biol 2014 Dec 28;36:204-12. Epub 2014 Sep 28.

Department of Pathology, The University of Chicago, 5841 South Maryland, MC1089, Chicago, IL 60637, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253049PMC
December 2014

An alteration of the gut-liver axis drives pulmonary inflammation after intoxication and burn injury in mice.

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Department of Surgery, Loyola University Medical Center, Maywood, Illinois; Burn and Shock Trauma Research Institute, Loyola University Medical Center, Maywood, Illinois; Alcohol Research Program, Loyola University Medical Center, Maywood, Illinois; Loyola University Chicago Stritch School of Medicine, Maywood, Illinois; and

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October 2014

Optical biopsy approaches in Barrett's esophagus with next-generation optical coherence tomography.

Gastrointest Endosc 2014 Sep;80(3):516-7

Center for Endoscopic Research and Therapeutics, University of Chicago, Chicago, Illinois, USA.

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September 2014

Commensal bacterial endocytosis in epithelial cells is dependent on myosin light chain kinase-activated brush border fanning by interferon-γ.

Am J Pathol 2014 Aug 7;184(8):2260-74. Epub 2014 Jun 7.

Graduate Institute of Physiology, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188866PMC
August 2014

Inflammation is an independent risk factor for colonic neoplasia in patients with ulcerative colitis: a case-control study.

Clin Gastroenterol Hepatol 2013 Dec 17;11(12):1601-8.e1-4. Epub 2013 Jul 17.

Department of Medicine, University of Chicago Medical Center, Chicago, Illinois. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840031PMC
December 2013

Intestinal permeability defects: is it time to treat?

Clin Gastroenterol Hepatol 2013 Sep 12;11(9):1075-83. Epub 2013 Jul 12.

Department of Pathology, The University of Chicago, Chicago, Illinois, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758766PMC
September 2013

Expanding the Lauren classification: a new gastric cancer subtype?

Gastroenterology 2013 Sep 25;145(3):505-8. Epub 2013 Jul 25.

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September 2013

TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis.

Gastroenterology 2013 Aug 22;145(2):407-15. Epub 2013 Apr 22.

Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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August 2013

Bifidobacteria stabilize claudins at tight junctions and prevent intestinal barrier dysfunction in mouse necrotizing enterocolitis.

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Division of Neonatology, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago Research Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

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May 2013

Endothelial and epithelial barriers in graft-versus-host disease.

Adv Exp Med Biol 2012 ;763:105-31

Department of Pathology, The University of Chicago, Chicago, Illinois, USA.

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April 2013

Reply to Skarupski and Keshavarzian.

Authors:
Jerrold R Turner

Gastroenterology 2013 Apr 26;144(4):e22-3. Epub 2013 Feb 26.

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April 2013

Capsaicin induces NKCC1 internalization and inhibits chloride secretion in colonic epithelial cells independently of TRPV1.

Am J Physiol Gastrointest Liver Physiol 2013 Jan 8;304(2):G142-56. Epub 2012 Nov 8.

Department of Surgery, The University of Chicago, Chicago, IL 60637, USA.

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January 2013

Inhibition of long myosin light-chain kinase activation alleviates intestinal damage after binge ethanol exposure and burn injury.

Am J Physiol Gastrointest Liver Physiol 2012 Sep 12;303(6):G705-12. Epub 2012 Jul 12.

Molecular and Cellular Biochemistry Program, Loyola University, Medical Center, Maywood, Illinois, USA.

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September 2012

Continuing attrition of physician-scientists (CAPS): a preventable syndrome?

Authors:
Jerrold R Turner

Gastroenterology 2012 Sep 21;143(3):511-515.e1. Epub 2012 Jul 21.

Department of Pathology, The University of Chicago, Chicago, Illinois.

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September 2012

Myosin light chain kinase: pulling the strings of epithelial tight junction function.

Ann N Y Acad Sci 2012 Jul;1258:34-42

Department of Pathology, University of Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2012.06526.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384706PMC
July 2012

Cyclic AMP dysregulates intestinal epithelial cell restitution through PKA and RhoA.

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Microbiology and Molecular Genetics, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA.

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June 2012

E-cadherin is critical for collective sheet migration and is regulated by the chemokine CXCL12 protein during restitution.

J Biol Chem 2012 Jun 1;287(26):22227-40. Epub 2012 May 1.

Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA.

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June 2012

Dynamic migration of γδ intraepithelial lymphocytes requires occludin.

Proc Natl Acad Sci U S A 2012 May 17;109(18):7097-102. Epub 2012 Apr 17.

Department of Pathology, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1073/pnas.1112519109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345021PMC
May 2012

Bundle-forming pilus retraction enhances enteropathogenic Escherichia coli infectivity.

Mol Biol Cell 2011 Jul 25;22(14):2436-47. Epub 2011 May 25.

Department of Cell and Developmental Biology, Institute of Life Sciences, Hebrew University of Jerusalem, Jerusalem 91904, Israel.

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July 2011