Jeroen L A Pennings

Jeroen L A Pennings

UNVERIFIED PROFILE

Are you Jeroen L A Pennings?   Register this Author

Register author
Jeroen L A Pennings

Jeroen L A Pennings

Publications by authors named "Jeroen L A Pennings"

Are you Jeroen L A Pennings?   Register this Author

100Publications

1537Reads

14Profile Views

Differential effects of fluoxetine and venlafaxine in the neural embryonic stem cell test (ESTn) revealed by a cell lineage map.

Neurotoxicology 2019 Oct 5. Epub 2019 Oct 5.

Center for Health Protection, National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720BA Bilthoven, the Netherlands; Institute for Risk Assessment Sciences (IRAS), Utrecht University, Yalelaan 2, 3584CM Utrecht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuro.2019.09.014DOI Listing
October 2019

Sensory evaluation of e-liquid flavors by smelling and vaping yields similar results.

Nicotine Tob Res 2019 Aug 22. Epub 2019 Aug 22.

Division of Human Nutrition and Health, Wageningen University, Stippeneng, WE Wageningen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ntr/ntz155DOI Listing
August 2019

The transcriptomic response to irinotecan in colon carcinoma bearing mice preconditioned by fasting.

Oncotarget 2019 Mar 15;10(22):2224-2234. Epub 2019 Mar 15.

Department of Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.26776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481335PMC
March 2019

Application of the comparison approach to open TG-GATEs: A useful toxicogenomics tool for detecting modes of action in chemical risk assessment.

Food Chem Toxicol 2018 Nov 8;121:115-123. Epub 2018 Aug 8.

Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fct.2018.08.007DOI Listing
November 2018

Cigarette Filter Ventilation and Smoking Protocol Influence Aldehyde Smoke Yields.

Chem Res Toxicol 2018 06 17;31(6):462-471. Epub 2018 May 17.

Centre for Health Protection , National Institute for Public Health and the Environment (RIVM) , P.O. Box 1, 3720 BA Bilthoven , The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.chemrestox.7b00342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008735PMC
June 2018

A transcriptomic approach for evaluating the relative potency and mechanism of action of azoles in the rat Whole Embryo Culture.

Toxicology 2017 12 29;392:96-105. Epub 2017 Sep 29.

National Institute of Public Health and the Environment (RIVM), 3720BA Bilthoven, the Netherlands; Institute for Risk Assessment Sciences (IRAS), Utrecht University, 3584CM Utrecht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tox.2017.09.014DOI Listing
December 2017

Embryotoxic and pharmacologic potency ranking of six azoles in the rat whole embryo culture by morphological and transcriptomic analysis.

Toxicol Appl Pharmacol 2017 05 3;322:15-26. Epub 2017 Mar 3.

National Institute of Public Health and the Environment (RIVM), Bilthoven, The Netherlands; Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.taap.2017.03.001DOI Listing
May 2017

Validation of precision-cut liver slices to study drug-induced cholestasis: a transcriptomics approach.

Arch Toxicol 2017 Mar 25;91(3):1401-1412. Epub 2016 Jun 25.

Division of Pharmacokinetics, Toxicology and Targeting, Groningen Research Institute for Pharmacy, University of Groningen, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00204-016-1778-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316400PMC
March 2017

Metabolic profiling of presymptomatic Huntington's disease sheep reveals novel biomarkers.

Sci Rep 2017 02 22;7:43030. Epub 2017 Feb 22.

Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep43030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320451PMC
February 2017

Cord blood gene expression supports that prenatal exposure to perfluoroalkyl substances causes depressed immune functionality in early childhood.

J Immunotoxicol 2016 27;13(2):173-80. Epub 2015 Mar 27.

c Division of Environmental Medicine , Norwegian Institute of Public Health (NIPH) , Oslo , Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/1547691X.2015.1029147DOI Listing
September 2016

Males are from Mars, and females are from Venus: sex-specific fetal brain gene expression signatures in a mouse model of maternal diet-induced obesity.

Am J Obstet Gynecol 2016 05 3;214(5):623.e1-623.e10. Epub 2016 Mar 3.

Division of Genetics, Department of Pediatrics, Floating Hospital for Children, Boston, MA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajog.2016.02.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851594PMC
May 2016

Biomarkers for circadian rhythm disruption independent of time of day.

PLoS One 2015 18;10(5):e0127075. Epub 2015 May 18.

Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127075PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436131PMC
April 2016

Transcriptome signature for dampened Th2 dominance in acellular pertussis vaccine-induced CD4(+) T cell responses through TLR4 ligation.

Sci Rep 2016 04 27;6:25064. Epub 2016 Apr 27.

Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep25064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846868PMC
April 2016

Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices.

Chem Res Toxicol 2016 Mar 9;29(3):342-51. Epub 2016 Mar 9.

National Institute for Public Health and the Environment , Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.chemrestox.5b00491DOI Listing
March 2016

First-Trimester Serum Acylcarnitine Levels to Predict Preeclampsia: A Metabolomics Approach.

Dis Markers 2015 4;2015:857108. Epub 2015 Jun 4.

Centre for Health Protection (GZB), National Institute for Public Health and the Environment (RIVM), 3720 BA Bilthoven, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2015/857108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471382PMC
February 2016

Zebrafish embryos as a screen for DNA methylation modifications after compound exposure.

Toxicol Appl Pharmacol 2016 Jan 19;291:84-96. Epub 2015 Dec 19.

Center for Health Protection, National Institute for Public Health and the Environment (RIVM), PO Box 1, 3720 BA Bilthoven, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.taap.2015.12.012DOI Listing
January 2016

Predictive performance of a seven-plex antibody array in prenatal screening for Down Syndrome.

Dis Markers 2015 23;2015:519851. Epub 2015 Apr 23.

Centre for Health Protection (GZB), National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720 BA Bilthoven, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2015/519851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423028PMC
December 2015

Development of an in vitro test to identify respiratory sensitizers in bronchial epithelial cells using gene expression profiling.

Toxicol In Vitro 2015 Dec 28;30(1 Pt B):274-80. Epub 2015 Oct 28.

Centre for Health Protection, National Institute for Public Health and the Environment, 3720 BA Bilthoven, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tiv.2015.10.010DOI Listing
December 2015

The fetal brain transcriptome and neonatal behavioral phenotype in the Ts1Cje mouse model of Down syndrome.

Am J Med Genet A 2015 Sep 14;167A(9):1993-2008. Epub 2015 May 14.

Mother Infant Research Institute, Tufts Medical Center and the Floating Hospital for Children, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajmg.a.37156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844354PMC
September 2015

An adverse outcome pathway framework for neural tube and axial defects mediated by modulation of retinoic acid homeostasis.

Reprod Toxicol 2015 Aug 16;55:104-13. Epub 2014 Oct 16.

Center for Health Protection, National Institute for Public Health and The Environment (RIVM), P.O. Box 1, 3720BA Bilthoven, The Netherlands; Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08906238140026
Publisher Site
http://dx.doi.org/10.1016/j.reprotox.2014.10.008DOI Listing
August 2015

Gene Expression Regulation and Pathway Analysis After Valproic Acid and Carbamazepine Exposure in a Human Embryonic Stem Cell-Based Neurodevelopmental Toxicity Assay.

Toxicol Sci 2015 Aug 15;146(2):311-20. Epub 2015 May 15.

*Laboratory for Health Protection Research, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands and Institute for Risk Assessment Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/toxsci/kfv094DOI Listing
August 2015

Comparison of gene expression regulation in mouse- and human embryonic stem cell assays during neural differentiation and in response to valproic acid exposure.

Reprod Toxicol 2015 Aug 11;56:77-86. Epub 2015 Jun 11.

Laboratory for Health Protection Research, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands; Institute for Risk Assessment Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.reprotox.2015.06.043DOI Listing
August 2015

Chronically Alternating Light Cycles Increase Breast Cancer Risk in Mice.

Curr Biol 2015 Jul;25(14):1932-7

Department of Genetics, Center for Biomedical Genetics, Erasmus University Medical Center, Rotterdam 3000 CA, the Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cub.2015.06.012DOI Listing
July 2015

Comparison of different blood collection, sample matrix, and immunoassay methods in a prenatal screening setting.

Dis Markers 2014 15;2014:509821. Epub 2014 Jul 15.

Centre for Health Protection (GZB), National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720 BA Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://www.hindawi.com/journals/dm/2014/509821/
Publisher Site
http://dx.doi.org/10.1155/2014/509821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123521PMC
April 2015

Metabolomics profiling for identification of novel potential markers in early prediction of preeclampsia.

PLoS One 2014 29;9(5):e98540. Epub 2014 May 29.

Leiden Academic Center for Drug Research, Division of Analytical Biosciences, Leiden University, Leiden, The Netherlands; The Netherlands Metabolomics Centre, Leiden University, Leiden, the Netherlands.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0098540PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038585PMC
January 2015

Analysis of adult cerebral cortex and hippocampus transcriptomes reveals unique molecular changes in the Ts1Cje mouse model of down syndrome.

Brain Pathol 2015 Jan 25;25(1):11-23. Epub 2014 Jul 25.

Mother Infant Research Institute, Floating Hospital for Children, Tufts Medical Center, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bpa.12151DOI Listing
January 2015

A transcriptomics-based hepatotoxicity comparison between the zebrafish embryo and established human and rodent in vitro and in vivo models using cyclosporine A, amiodarone and acetaminophen.

Toxicol Lett 2015 Jan 24;232(2):403-12. Epub 2014 Nov 24.

Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720 BA Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03784274140147
Publisher Site
http://dx.doi.org/10.1016/j.toxlet.2014.11.020DOI Listing
January 2015

Gene expression markers in the zebrafish embryo reflect a hepatotoxic response in animal models and humans.

Toxicol Lett 2014 Oct 24;230(1):48-56. Epub 2014 Jul 24.

Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720 BA Bilthoven, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03784274140109
Publisher Site
http://dx.doi.org/10.1016/j.toxlet.2014.06.844DOI Listing
October 2014

Comparison of the molecular topologies of stress-activated transcription factors HSF1, AP-1, NRF2, and NF-κB in their induction kinetics of HMOX1.

Biosystems 2014 Oct 6;124:75-85. Epub 2014 Sep 6.

Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), P.O. Box 1, NL-3720BA Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03032647140012
Publisher Site
http://dx.doi.org/10.1016/j.biosystems.2014.09.005DOI Listing
October 2014

A statistical approach towards the derivation of predictive gene sets for potency ranking of chemicals in the mouse embryonic stem cell test.

Toxicol Lett 2014 Mar 27;225(3):342-9. Epub 2014 Jan 27.

Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands; Institute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.toxlet.2014.01.017DOI Listing
March 2014

Unraveling toxicological mechanisms and predicting toxicity classes with gene dysregulation networks.

J Appl Toxicol 2013 Dec 10;33(12):1407-15. Epub 2012 Aug 10.

Laboratory for Health Protection Research, National Institute for Public Health and the Environment, PO Box 1, NL-3720, BA, Bilthoven, the Netherlands; Department of Toxicogenomics, Maastricht University, PO Box 616, NL-6200, MD, Maastricht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jat.2800DOI Listing
December 2013

Identification of interleukin-1 beta, but no other inflammatory proteins, as an early onset pre-eclampsia biomarker in first trimester serum by bead-based multiplexed immunoassays.

Prenat Diagn 2013 Dec 31;33(12):1183-8. Epub 2013 Aug 31.

Centre for Infectious Disease Research, Diagnostics and Screening (IDS), National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pd.4219DOI Listing
December 2013

Slow accumulation of mutations in Xpc-/- mice upon induction of oxidative stress.

DNA Repair (Amst) 2013 Dec 29;12(12):1081-6. Epub 2013 Sep 29.

National Institute for Public Health and the Environment, Center for Health Protection, Bilthoven 3721 MA, The Netherlands; Leiden University Medical Center, Department of Toxicogenetics, Leiden 2300 RC, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.dnarep.2013.08.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847164PMC
December 2013

Valproic acid-induced gene expression responses in rat whole embryo culture and comparison across in vitro developmental and non-developmental models.

Reprod Toxicol 2013 Nov 28;41:57-66. Epub 2013 Jun 28.

Centre for Health Protection, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.reprotox.2013.06.069DOI Listing
November 2013

Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis.

Toxicol Lett 2013 Aug 3;221(3):225-36. Epub 2013 Jul 3.

Center for Health Protection, National Institute for Public Health and the Environment-RIVM, 3720 BA, Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.toxlet.2013.06.236DOI Listing
August 2013

Quantitative proteomics reveals distinct differences in the protein content of outer membrane vesicle vaccines.

J Proteome Res 2013 Apr 25;12(4):1898-908. Epub 2013 Feb 25.

Institute for Translational Vaccinology (Intravacc) , Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/pr301208gDOI Listing
April 2013

In vitro effects of aldehydes present in tobacco smoke on gene expression in human lung alveolar epithelial cells.

Toxicol In Vitro 2013 Apr 14;27(3):1072-81. Epub 2013 Feb 14.

Department of Toxicology, NUTRIM School for Nutrition, Toxicology & Metabolism, Maastricht University, Maastricht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tiv.2013.02.003DOI Listing
April 2013

Complementary detection of embryotoxic properties of substances in the neural and cardiac embryonic stem cell tests.

Toxicol Sci 2013 Mar 13;132(1):118-30. Epub 2012 Dec 13.

National Institute for Public Health and the Environment, Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
https://academic.oup.com/toxsci/article-lookup/doi/10.1093/t
Publisher Site
http://dx.doi.org/10.1093/toxsci/kfs333DOI Listing
March 2013

Dose response analysis of monophthalates in the murine embryonic stem cell test assessed by cardiomyocyte differentiation and gene expression.

Reprod Toxicol 2013 Jan 17;35:81-8. Epub 2012 Jul 17.

Laboratory for Health Protection Research, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.reprotox.2012.07.002DOI Listing
January 2013

Host response to mechanical ventilation for viral respiratory tract infection.

Eur Respir J 2012 Dec 10;40(6):1508-15. Epub 2012 Apr 10.

Dept of Pediatric Intensive Care, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1183/09031936.00177111DOI Listing
December 2012

An optimized gene set for transcriptomics based neurodevelopmental toxicity prediction in the neural embryonic stem cell test.

Toxicology 2012 Oct 1;300(3):158-67. Epub 2012 Jul 1.

Laboratory for Health Protection Research (GBO), National Institute for Public Health and the Environment, (RIVM), Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tox.2012.06.016DOI Listing
October 2012

Dose-response analysis of phthalate effects on gene expression in rat whole embryo culture.

Toxicol Appl Pharmacol 2012 Oct 24;264(1):32-41. Epub 2012 Jul 24.

National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.taap.2012.07.015DOI Listing
October 2012

A bead-based multiplexed immunoassay to evaluate breast cancer biomarkers for early detection in pre-diagnostic serum.

Int J Mol Sci 2012 Oct 22;13(10):13587-604. Epub 2012 Oct 22.

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms131013587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497343PMC
October 2012

A review of toxicogenomic approaches in developmental toxicology.

Methods Mol Biol 2012 ;889:347-71

National Institute for Public Health and the Environment-RIVM, Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-61779-867-2_22DOI Listing
September 2012

Biomarker discovery using a comparative omics approach in a mouse model developing heterogeneous mammary cancer subtypes.

Proteomics 2012 Jul;12(13):2149-57

Laboratory for Health Protection Research (GBO), National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pmic.201100497DOI Listing
July 2012

A comparison of gene expression responses in rat whole embryo culture and in vivo: time-dependent retinoic acid-induced teratogenic response.

Toxicol Sci 2012 Mar 18;126(1):242-54. Epub 2012 Jan 18.

Laboratory for Health Protection Research, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/toxsci/kfr342DOI Listing
March 2012

Transcriptomic concentration-response evaluation of valproic acid, cyproconazole, and hexaconazole in the neural embryonic stem cell test (ESTn).

Toxicol Sci 2012 Feb 1;125(2):430-8. Epub 2011 Nov 1.

Laboratory for Health Protection Research, National Institute for Public Health and the Environment (RIVM), 3720 BA Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
https://academic.oup.com/toxsci/article-lookup/doi/10.1093/t
Publisher Site
http://dx.doi.org/10.1093/toxsci/kfr293DOI Listing
February 2012

Effects of pooling RNA from samples treated with different compounds for determining class specific biomarkers and processes in toxicogenomics.

Toxicol In Vitro 2011 Dec 19;25(8):1841-7. Epub 2011 May 19.

Health Protection Research, National Institute for Public Health and the Environment (GBO, RIVM), Antonie van Leeuwenhoeklaan 9, 3721 MA Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tiv.2011.05.012DOI Listing
December 2011

Integrative data mining to identify novel candidate serum biomarkers for pre-eclampsia screening.

Prenat Diagn 2011 Dec 22;31(12):1153-9. Epub 2011 Sep 22.

Laboratory for Health Protection Research, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pd.2850DOI Listing
December 2011

Quantitative performance of antibody array technology in a prenatal screening setting.

Clin Chem Lab Med 2011 Oct 28;50(2):325-32. Epub 2011 Oct 28.

Laboratory for Health Protection Research, National Institute of Public Health and the Environment, Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1515/CCLM.2011.767DOI Listing
October 2011

Deregulation of cancer-related pathways in primary hepatocytes derived from DNA repair-deficient Xpa-/-p53+/- mice upon exposure to benzo[a]pyrene.

Toxicol Sci 2011 Sep 29;123(1):123-32. Epub 2011 Jun 29.

Laboratory for Health Protection Research, National Institute for Public Health and the Environment, 3720 BA Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
https://academic.oup.com/toxsci/article-lookup/doi/10.1093/t
Publisher Site
http://dx.doi.org/10.1093/toxsci/kfr169DOI Listing
September 2011

Time-response evaluation by transcriptomics of methylmercury effects on neural differentiation of murine embryonic stem cells.

Toxicol Sci 2011 Aug 25;122(2):437-47. Epub 2011 May 25.

Laboratory for Health Protection Research, National Institute for Public Health and the Environment (RIVM), 3720 BA Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/toxsci/kfr134DOI Listing
August 2011

Gene set assembly for quantitative prediction of developmental toxicity in the embryonic stem cell test.

Toxicology 2011 Jun 5;284(1-3):63-71. Epub 2011 Apr 5.

Laboratory for Health Protection Research, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tox.2011.03.017DOI Listing
June 2011

Gene expression profiles induced by Salmonella infection in resistant and susceptible mice.

Microbes Infect 2011 Apr 20;13(4):383-93. Epub 2011 Jan 20.

Department of Bacteriology, Veterinary Laboratories Agency (Weybridge), Woodham Lane, Addlestone, Surrey KT15 3NB, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.micinf.2011.01.001DOI Listing
April 2011

Concentration-dependent gene expression responses to flusilazole in embryonic stem cell differentiation cultures.

Toxicol Appl Pharmacol 2011 Mar 28;251(2):110-8. Epub 2010 Dec 28.

Laboratory for Health Protection Research, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.taap.2010.12.008DOI Listing
March 2011

Discriminating classes of developmental toxicants using gene expression profiling in the embryonic stem cell test.

Toxicol Lett 2011 Mar 30;201(2):143-51. Epub 2010 Dec 30.

Laboratory for Health Protection Research, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S037842741001814
Publisher Site
http://dx.doi.org/10.1016/j.toxlet.2010.12.019DOI Listing
March 2011

Protein expression profiling of mouse thymoma cells upon exposure to the trichothecene deoxynivalenol (DON): implications for its mechanism of action.

J Immunotoxicol 2010 Jul-Sep;7(3):147-56

National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
February 2011

Identification by gene coregulation mapping of novel genes involved in embryonic stem cell differentiation.

Stem Cells Dev 2011 Jan 18;20(1):115-26. Epub 2010 Aug 18.

Laboratory for Health Protection Research, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/scd.2010.0181DOI Listing
January 2011

Evaluation of developmental toxicant identification using gene expression profiling in embryonic stem cell differentiation cultures.

Toxicol Sci 2011 Jan 8;119(1):126-34. Epub 2010 Oct 8.

Laboratory for Health Protection Research, National Institute for Public Health and the Environment, 3720 BA Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
https://academic.oup.com/toxsci/article/1635540/Evaluation
Publisher Site
http://dx.doi.org/10.1093/toxsci/kfq291DOI Listing
January 2011

Application of toxicogenomics in hepatic systems toxicology for risk assessment: acetaminophen as a case study.

Toxicol Appl Pharmacol 2011 Jan 21;250(2):96-107. Epub 2010 Oct 21.

Laboratory for Health Protection Research, National Institute of Public Health and the Environment (RIVM), PO Box 1, 3720 BA Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.taap.2010.10.013DOI Listing
January 2011

Embryotoxicant-specific transcriptomic responses in rat postimplantation whole-embryo culture.

Toxicol Sci 2010 Dec 23;118(2):675-85. Epub 2010 Sep 23.

Laboratory for Health Protection Research, National Institute for Public Health and the Environment (RIVM), 3720 BA Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/toxsci/kfq292DOI Listing
December 2010

Transcriptomics analysis of retinoic acid embryotoxicity in rat postimplantation whole embryo culture.

Reprod Toxicol 2010 Sep 19;30(2):333-40. Epub 2010 May 19.

Laboratory for Health Protection Research, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.reprotox.2010.05.013DOI Listing
September 2010

Proteome profiling of mouse embryonic stem cells to define markers for cell differentiation and embryotoxicity.

Reprod Toxicol 2010 Sep 27;30(2):322-32. Epub 2010 May 27.

Laboratory for Health Protection Research, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S089062381000193
Publisher Site
http://dx.doi.org/10.1016/j.reprotox.2010.05.084DOI Listing
September 2010

Keratinocyte gene expression profiles discriminate sensitizing and irritating compounds.

Toxicol Sci 2010 Sep 20;117(1):81-9. Epub 2010 Jun 20.

Laboratory for Health Protection Research, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/toxsci/kfq182DOI Listing
September 2010

Monitoring developmental toxicity in the embryonic stem cell test using differential gene expression of differentiation-related genes.

Toxicol Sci 2010 Jul 26;116(1):130-9. Epub 2010 Apr 26.

Laboratory for Health Protection Research, National Institute for Public Health and the Environment (RIVM), 3720 BA Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/toxsci/kfq127DOI Listing
July 2010

Identification of breast cancer biomarkers in transgenic mouse models: A proteomics approach.

Proteomics Clin Appl 2010 Jul 24;4(6-7):603-12. Epub 2010 Mar 24.

Laboratory for Health Protection Research, National Institute of Public Health and the Environment, Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/prca.200900175DOI Listing
July 2010

Down syndrome screening: imagining the screening test of the future.

Expert Rev Mol Diagn 2010 May;10(4):445-57

National Institute for Public Health and the Environment (RIVM), PO Box 1, NL-3720BA Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1586/erm.10.32DOI Listing
May 2010

Benzo(a)pyrene induces similar gene expression changes in testis of DNA repair proficient and deficient mice.

BMC Genomics 2010 May 26;11:333. Epub 2010 May 26.

Department of Health Risk Analysis and Toxicology, School for Nutrition, Toxicology and Metabolism, Maastricht University, PO box 616, 6200 MD Maastricht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2164-11-333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887421PMC
May 2010

Transcriptomics-based identification of developmental toxicants through their interference with cardiomyocyte differentiation of embryonic stem cells.

Toxicol Appl Pharmacol 2010 Mar 28;243(3):420-8. Epub 2009 Dec 28.

Laboratory for Health Protection Research, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.taap.2009.12.021DOI Listing
March 2010

Transcriptional profiling of the acute pulmonary inflammatory response induced by LPS: role of neutrophils.

Respir Res 2010 Feb 25;11:24. Epub 2010 Feb 25.

Department of Health Risk Analysis and Toxicology, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University, PO box 616, 6200 MD, Maastricht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1465-9921-11-24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838834PMC
February 2010

Comparison of clastogen-induced gene expression profiles in wild-type and DNA repair-deficient Rad54/Rad54B cells.

BMC Genomics 2010 Jan 12;11:24. Epub 2010 Jan 12.

National Institute for Public Health and the Environment (RIVM), Laboratory for Health Protection Research (GBO), NL-3720 BA Bilthoven, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2164-11-24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824718PMC
January 2010

Chemokine induction by all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia: triggering the differentiation syndrome.

Blood 2009 Dec 14;114(27):5512-21. Epub 2009 Oct 14.

Central Hematology Laboratory and Department of Hematology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2009-02-204834DOI Listing
December 2009

Discovery of novel serum biomarkers for prenatal Down syndrome screening by integrative data mining.

PLoS One 2009 Nov 24;4(11):e8010. Epub 2009 Nov 24.

Laboratory for Health Protection Research (GBO), National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0008010PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777317PMC
November 2009

Proteomic analysis of mouse thymoma EL4 cells treated with bis(tri-n-butyltin)oxide (TBTO).

J Immunotoxicol 2009 Sep;6(3):174-83

National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/15476910903496691DOI Listing
September 2009

Gene expression changes in the mesenteric lymph nodes of rats after oral peanut extract exposure.

J Immunotoxicol 2008 Oct;5(4):385-94

University Maastricht, Nutrition and Toxicology Research Institute Maastricht, Department of Health Risk Analysis and Toxicology, Maastricht, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15476910802586126DOI Listing
October 2008

Gene expression profiling of Bis(tri-n-butyltin)oxide (TBTO)-induced immunotoxicity in mice and rats.

J Immunotoxicol 2006 Dec;3(4):227-44

Department of Health Risk Analysis and Toxicology (GRAT), Nutrition and Toxicology Research Institute Maastricht (NUTRIM), Maastricht University, Maastricht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15476910601023602DOI Listing
December 2006