Jeroen Korving

Jeroen Korving

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Jeroen Korving

Jeroen Korving

Publications by authors named "Jeroen Korving"

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34Publications

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Mouse and human urothelial cancer organoids: A tool for bladder cancer research.

Proc Natl Acad Sci U S A 2019 Feb 20. Epub 2019 Feb 20.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, 3584 CT Utrecht, The Netherlands;

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http://dx.doi.org/10.1073/pnas.1803595116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410883PMC
February 2019

Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids.

Cell 2018 11;175(6):1591-1606.e19

Oncode Institute, Hubrecht Institute, KNAW (Royal Netherlands Academy of Arts and Sciences), Utrecht, the Netherlands; University Medical Center Utrecht, Cancer Genomics Netherlands, 3584CX Utrecht, the Netherlands; The Princess Maxima Center for Pediatric Oncology, Utrecht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.11.013DOI Listing
November 2018

Blastocyst-like structures generated solely from stem cells.

Nature 2018 05 2;557(7703):106-111. Epub 2018 May 2.

Hubrecht Institute for Developmental Biology and Stem Cell Research, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/s41586-018-0051-0DOI Listing
May 2018

Generation of an inducible colon-specific Cre enzyme mouse line for colon cancer research.

Proc Natl Acad Sci U S A 2016 10 5;113(42):11859-11864. Epub 2016 Oct 5.

Hubrecht Institute for Developmental Biology and Stem Cell Research, Royal Netherlands Academy of Arts and Sciences (KNAW), 3584 CT Utrecht, The Netherlands; University Medical Centre Utrecht, 3584 CT Utrecht, The Netherlands;

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http://dx.doi.org/10.1073/pnas.1614057113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081651PMC
October 2016

Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters.

Cell Stem Cell 2016 Feb 28;18(2):203-13. Epub 2016 Jan 28.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center, Utrecht, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2016.01.001DOI Listing
February 2016

Visualization of a short-range Wnt gradient in the intestinal stem-cell niche.

Nature 2016 Feb 10;530(7590):340-3. Epub 2016 Feb 10.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht, 3584CT Utrecht, the Netherlands.

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http://dx.doi.org/10.1038/nature16937DOI Listing
February 2016

Sequential cancer mutations in cultured human intestinal stem cells.

Nature 2015 May 29;521(7550):43-7. Epub 2015 Apr 29.

1] Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, 3584CT Utrecht, The Netherlands [2] Cancer Genomics Netherlands, UMC Utrecht, 3584CG Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/nature14415DOI Listing
May 2015

Large-scale identification of coregulated enhancer networks in the adult human brain.

Cell Rep 2014 Oct 16;9(2):767-79. Epub 2014 Oct 16.

Hubrecht Institute-KNAW & University Medical Center Utrecht, Uppsalalaan 8, 3584CT, Utrecht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.09.023DOI Listing
October 2014

Mapping early fate determination in Lgr5+ crypt stem cells using a novel Ki67-RFP allele.

EMBO J 2014 Sep 4;33(18):2057-68. Epub 2014 Aug 4.

Hubrecht Institute - KNAW and University Medical Centre Utrecht, Utrecht, The Netherlands

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http://dx.doi.org/10.15252/embj.201488017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195772PMC
September 2014

Dll1+ secretory progenitor cells revert to stem cells upon crypt damage.

Nat Cell Biol 2012 10 23;14(10):1099-1104. Epub 2012 Sep 23.

Hubrecht Institute for Developmental Biology and Stem Cell Research & University Medical Centre Utrecht, Uppsalalaan 8, 3584CT Utrecht, Netherlands.

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http://dx.doi.org/10.1038/ncb2581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789123PMC
October 2012

A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal.

Mol Cell Biol 2012 May 5;32(10):1918-27. Epub 2012 Mar 5.

Hubrecht Institute for Developmental Biology and Stem Cell Research & University Medical Centre Utrecht, Utrecht, Netherlands.

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http://dx.doi.org/10.1128/MCB.06288-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347420PMC
May 2012

von Hippel-Lindau tumor suppressor mutants faithfully model pathological hypoxia-driven angiogenesis and vascular retinopathies in zebrafish.

Dis Model Mech 2010 May-Jun;3(5-6):343-53. Epub 2010 Mar 24.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1242/dmm.004036DOI Listing
September 2010

T-cell factor 4 (tcf7l2) is the main effector of Wnt signaling during zebrafish intestine organogenesis.

Zebrafish 2009 Mar;6(1):59-68

Hubrecht Institute for Developmental Biology and Stem Cell Research, Utrecht, The Netherlands.

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http://dx.doi.org/10.1089/zeb.2009.0580DOI Listing
March 2009

Zebrafish with mutations in mismatch repair genes develop neurofibromas and other tumors.

Cancer Res 2008 Jul;68(13):5059-66

Hubrecht Institute for Developmental Biology and Stem Cell Research, Cancer Genomics Center, Utrecht University, Utrecht, the Netherlands.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-0019DOI Listing
July 2008

Lack of DNA mismatch repair protein MSH6 in the rat results in hereditary non-polyposis colorectal cancer-like tumorigenesis.

Carcinogenesis 2008 Jun 15;29(6):1290-7. Epub 2008 Apr 15.

Hubrecht Institute for Developmental Biology and Stem Cell Research, Cancer Genomics Center, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/carcin/bgn094DOI Listing
June 2008

T-cell factor 4 (Tcf7l2) maintains proliferative compartments in zebrafish intestine.

EMBO Rep 2007 Oct 7;8(10):966-73. Epub 2007 Sep 7.

Netherlands Institute for Developmental Biology, Center for Biomedical Research, Hubrecht Institute, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/sj.embor.7401071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2002560PMC
October 2007

Identification of stem cells in small intestine and colon by marker gene Lgr5.

Nature 2007 Oct 14;449(7165):1003-7. Epub 2007 Oct 14.

Hubrecht Institute, Uppsalalaan 8, 3584CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/nature06196DOI Listing
October 2007

Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE.

Development 2007 Feb;134(3):535-44

Department of Molecular Biology and Pharmacology and the Department of Medicine, Division of Dermatology, Washington University Medical School, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1242/dev.02733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583343PMC
February 2007

Function and regulation of Alx4 in limb development: complex genetic interactions with Gli3 and Shh.

Dev Biol 2005 Sep 21;285(2):533-44. Epub 2005 Jul 21.

Hubrecht Laboratory, The Netherlands Institute for Developmental Biology, Uppsalalaan 8, 3584CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.ydbio.2005.06.017DOI Listing
September 2005

The Wnt/beta-catenin pathway regulates cardiac valve formation.

Nature 2003 Oct;425(6958):633-7

Netherlands Institute for Developmental Biology, Hubrecht Laboratory and Centre for Biomedical Genetics, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/nature02028DOI Listing
October 2003