Publications by authors named "Jeroen H F de Baaij"

48Publications

Genetics of renovascular hypertension in children.

J Hypertens 2020 Oct;38(10):1964-1970

Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Foundation Trust.

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http://dx.doi.org/10.1097/HJH.0000000000002491DOI Listing
October 2020

Mechanisms coupling sodium and magnesium reabsorption in the distal convoluted tubule of the kidney.

Acta Physiol (Oxf) 2020 Jun 30:e13528. Epub 2020 Jun 30.

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1111/apha.13528DOI Listing
June 2020

Genetics of renovascular hypertension in children.

J Hypertens 2020 Jun 12. Epub 2020 Jun 12.

Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Foundation Trust.

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http://dx.doi.org/10.1097/HJH.0000000000002491DOI Listing
June 2020

Low serum magnesium as a risk factor for peripheral artery disease in chronic kidney disease: an open verdict.

Nephrol Dial Transplant 2020 Jun 3. Epub 2020 Jun 3.

Department of Physiology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/ndt/gfaa115DOI Listing
June 2020

Metformin regulates TRPM6, a potential explanation for magnesium imbalance in type 2 diabetes patients.

Can J Physiol Pharmacol 2020 Jun 4;98(6):400-411. Epub 2020 Feb 4.

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1139/cjpp-2019-0570DOI Listing
June 2020

Magnesium prevents vascular calcification in Klotho deficiency.

Kidney Int 2020 03 2;97(3):487-501. Epub 2019 Nov 2.

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2019.09.034DOI Listing
March 2020

Calciprotein particle inhibition explains magnesium-mediated protection against vascular calcification.

Nephrol Dial Transplant 2020 05;35(5):765-773

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/ndt/gfz190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203562PMC
May 2020

Development of a villi-like micropatterned porous membrane for intestinal magnesium and calcium uptake studies.

Acta Biomater 2019 11 26;99:110-120. Epub 2019 Aug 26.

Department of Physiology, Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center (Radboudumc), Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2019.08.041DOI Listing
November 2019

Low gut microbiota diversity and dietary magnesium intake are associated with the development of PPI-induced hypomagnesemia.

FASEB J 2019 10 12;33(10):11235-11246. Epub 2019 Jul 12.

Department of Physiology, Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center (RADBOUDUMC), Nijmegen, The Netherlands.

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http://dx.doi.org/10.1096/fj.201900839RDOI Listing
October 2019

Low extracellular magnesium does not impair glucose-stimulated insulin secretion.

PLoS One 2019 4;14(6):e0217925. Epub 2019 Jun 4.

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0217925PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548430PMC
February 2020

Magnesium and calciprotein particles in vascular calcification: the good cop and the bad cop.

Curr Opin Nephrol Hypertens 2019 07;28(4):368-374

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1097/MNH.0000000000000509DOI Listing
July 2019

Renal phospholipidosis and impaired magnesium handling in high-fat-diet-fed mice.

FASEB J 2019 06 8;33(6):7192-7201. Epub 2019 Mar 8.

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1096/fj.201801778RRDOI Listing
June 2019

Effect of Dapagliflozin Treatment on the Expression of Renal Sodium Transporters/Channels on High-Fat Diet Diabetic Mice.

Nephron 2019 22;142(1):51-60. Epub 2019 Feb 22.

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands,

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http://dx.doi.org/10.1159/000496617DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530118PMC
December 2019

Diabetes-induced hypomagnesemia is not modulated by metformin treatment in mice.

Sci Rep 2019 02 11;9(1):1770. Epub 2019 Feb 11.

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud university medical center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/s41598-018-38351-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370757PMC
February 2019

SLC41A1 is essential for magnesium homeostasis in vivo.

Pflugers Arch 2019 06 12;471(6):845-860. Epub 2018 Nov 12.

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s00424-018-2234-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533229PMC
June 2019

Magnesium deficiency prevents high-fat-diet-induced obesity in mice.

Diabetologia 2018 09 9;61(9):2030-2042. Epub 2018 Jul 9.

Department of Physiology (286), Radboud Institute for Molecular Life Sciences, Radboud university medical center, P. O. Box 9101, 6500 HB, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1007/s00125-018-4680-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096631PMC
September 2018

A de novo KCNA1 Mutation in a Patient with Tetany and Hypomagnesemia.

Nephron 2018 23;139(4):359-366. Epub 2018 May 23.

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1159/000488954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492638PMC
September 2019

Transcription factor HNF1β regulates expression of the calcium-sensing receptor in the thick ascending limb of the kidney.

Am J Physiol Renal Physiol 2018 07 21;315(1):F27-F35. Epub 2018 Mar 21.

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center , Nijmegen , The Netherlands.

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http://dx.doi.org/10.1152/ajprenal.00601.2017DOI Listing
July 2018

The rise and fall of novel renal magnesium transporters.

Am J Physiol Renal Physiol 2018 06 7;314(6):F1027-F1033. Epub 2018 Feb 7.

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center , Nijmegen , The Netherlands.

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http://dx.doi.org/10.1152/ajprenal.00634.2017DOI Listing
June 2018

Magnesium prevents vascular calcification in vitro by inhibition of hydroxyapatite crystal formation.

Sci Rep 2018 02 1;8(1):2069. Epub 2018 Feb 1.

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud university medical center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/s41598-018-20241-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794996PMC
February 2018

Rebuttal from Francisco J. Arjona and Jeroen H. F. de Baaij.

J Physiol 2018 03 31;596(5):753-754. Epub 2018 Jan 31.

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1113/JP275705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830431PMC
March 2018

CrossTalk opposing view: CNNM proteins are not Na /Mg exchangers but Mg transport regulators playing a central role in transepithelial Mg (re)absorption.

J Physiol 2018 03 31;596(5):747-750. Epub 2018 Jan 31.

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1113/JP275249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830416PMC
March 2018

Magnesium Counteracts Vascular Calcification: Passive Interference or Active Modulation?

Arterioscler Thromb Vasc Biol 2017 08 29;37(8):1431-1445. Epub 2017 Jun 29.

From the Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands (A.D.t.B., J.H.F.d.B.); Cardiovascular Division, BHF Centre of Research Excellence, James Black Centre, King's College, London, United Kingdom (C.M.S.); and Department of Physiology, Anatomy and Genetics, University of Oxford, United Kingdom (J.H.F.d.B.).

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http://dx.doi.org/10.1161/ATVBAHA.117.309182DOI Listing
August 2017

Loss of transcriptional activation of the potassium channel Kir5.1 by HNF1β drives autosomal dominant tubulointerstitial kidney disease.

Kidney Int 2017 11 31;92(5):1145-1156. Epub 2017 May 31.

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2017.03.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903269PMC
November 2017

Serum magnesium and the risk of prediabetes: a population-based cohort study.

Diabetologia 2017 05 21;60(5):843-853. Epub 2017 Feb 21.

Department of Internal Medicine, Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1007/s00125-017-4224-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518103PMC
May 2017

Common single nucleotide polymorphisms in transient receptor potential melastatin type 6 increase the risk for proton pump inhibitor-induced hypomagnesemia: a case-control study.

Pharmacogenet Genomics 2017 03;27(3):83-88

Departments of aPhysiology bGastroenterology and Hepatology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen cDepartment of Gastroenterology, Bernhoven Hospital, Uden dDepartment of Gastroenterology, Canisius-Wilhelmina-Hospital, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1097/FPC.0000000000000259DOI Listing
March 2017

Determinants of hypomagnesemia in patients with type 2 diabetes mellitus.

Eur J Endocrinol 2017 Jan 5;176(1):11-19. Epub 2016 Oct 5.

Departments of Physiology

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http://dx.doi.org/10.1530/EJE-16-0517DOI Listing
January 2017

Identification of SLC41A3 as a novel player in magnesium homeostasis.

Sci Rep 2016 06 28;6:28565. Epub 2016 Jun 28.

Department of Physiology Radboud Institute for Molecular Life Sciences, Radboud university medical center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/srep28565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923877PMC
June 2016

P2X6 Knockout Mice Exhibit Normal Electrolyte Homeostasis.

PLoS One 2016 2;11(6):e0156803. Epub 2016 Jun 2.

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0156803PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890750PMC
July 2017

Genetic causes of hypomagnesemia, a clinical overview.

Pediatr Nephrol 2017 Jul 27;32(7):1123-1135. Epub 2016 May 27.

Centre for Nephrology, University College London, London, UK.

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http://dx.doi.org/10.1007/s00467-016-3416-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440500PMC
July 2017

Hypomagnesemia in Type 2 Diabetes: A Vicious Circle?

Diabetes 2016 Jan;65(1):3-13

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, U.K.

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http://diabetes.diabetesjournals.org/content/65/1/3.full.pdf
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http://diabetes.diabetesjournals.org/lookup/doi/10.2337/db15
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http://dx.doi.org/10.2337/db15-1028DOI Listing
January 2016

The art of magnesium transport.

Magnes Res 2015 Jul-Sep;28(3):85-91

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud university medical center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1684/mrh.2015.0388DOI Listing
August 2016

Dietary Inulin Fibers Prevent Proton-Pump Inhibitor (PPI)-Induced Hypocalcemia in Mice.

PLoS One 2015 23;10(9):e0138881. Epub 2015 Sep 23.

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud university medical center, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0138881PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580428PMC
May 2016

Flavaglines Stimulate Transient Receptor Potential Melastatin Type 6 (TRPM6) Channel Activity.

PLoS One 2015 16;10(3):e0119028. Epub 2015 Mar 16.

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0119028PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361557PMC
January 2016

Recurrent FXYD2 p.Gly41Arg mutation in patients with isolated dominant hypomagnesaemia.

Nephrol Dial Transplant 2015 Jun 11;30(6):952-7. Epub 2015 Mar 11.

Department of Medical Genetics, University Medical Centre Utrecht, Utrecht 3508 AB, The Netherlands.

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http://dx.doi.org/10.1093/ndt/gfv014DOI Listing
June 2015

Magnesium in man: implications for health and disease.

Physiol Rev 2015 Jan;95(1):1-46

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://www.physiology.org/doi/10.1152/physrev.00012.2014
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http://dx.doi.org/10.1152/physrev.00012.2014DOI Listing
January 2015

P2X4 receptor regulation of transient receptor potential melastatin type 6 (TRPM6) Mg2+ channels.

Pflugers Arch 2014 Oct 12;466(10):1941-52. Epub 2014 Jan 12.

Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, P.O. Box 9101, 6500, HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s00424-014-1440-3DOI Listing
October 2014

Elucidation of the distal convoluted tubule transcriptome identifies new candidate genes involved in renal Mg(2+) handling.

Am J Physiol Renal Physiol 2013 Dec 2;305(11):F1563-73. Epub 2013 Oct 2.

Dept. of Physiology (286 Radboud Univ. Nijmegen Medical Centre, Nijmegen Centre for Molecular Life Sciences, PO Box 9101, Nijmegen 6500 HB, The Netherlands.

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http://www.physiology.org/doi/10.1152/ajprenal.00322.2013
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http://dx.doi.org/10.1152/ajprenal.00322.2013DOI Listing
December 2013

Membrane topology and intracellular processing of cyclin M2 (CNNM2).

J Biol Chem 2012 Apr 7;287(17):13644-55. Epub 2012 Mar 7.

Department of Physiology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1074/jbc.M112.342204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340180PMC
April 2012

Regulation of magnesium balance: lessons learned from human genetic disease.

Clin Kidney J 2012 Feb;5(Suppl 1):i15-i24

Department of Physiology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/ndtplus/sfr164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455826PMC
February 2012