Publications by authors named "Jeroen D Langereis"

50Publications

Antibody Binding and Complement-Mediated Killing of Invasive Haemophilus influenzae Isolates from Spain, Portugal, and the Netherlands.

Infect Immun 2020 Sep 18;88(10). Epub 2020 Sep 18.

Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands

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http://dx.doi.org/10.1128/IAI.00454-20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504965PMC
September 2020

Viral-bacterial (co-)occurrence in the upper airways and the risk of childhood pneumonia in resource-limited settings.

J Infect 2020 Aug 10;81(2):213-220. Epub 2020 Jun 10.

Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1016/j.jinf.2020.06.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392802PMC
August 2020

Unraveling Haemophilus influenzae virulence mechanisms enable discovery of new targets for antimicrobials and vaccines.

Curr Opin Infect Dis 2020 06;33(3):231-237

Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences.

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http://dx.doi.org/10.1097/QCO.0000000000000645DOI Listing
June 2020

Common Genetic Variants in the Complement System and their Potential Link with Disease Susceptibility and Outcome of Invasive Bacterial Infection.

J Innate Immun 2020 3;12(2):131-141. Epub 2019 Jul 3.

Section Paediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboudumc, Nijmegen, The Netherlands,

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http://dx.doi.org/10.1159/000500545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098274PMC
July 2019

Serum IgM and C-Reactive Protein Binding to Phosphorylcholine of Nontypeable Increases Complement-Mediated Killing.

Infect Immun 2019 08 23;87(8). Epub 2019 Jul 23.

Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1128/IAI.00299-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652778PMC
August 2019

Uptake of Sialic Acid by Nontypeable Haemophilus influenzae Increases Complement Resistance through Decreasing IgM-Dependent Complement Activation.

Infect Immun 2019 06 21;87(6). Epub 2019 May 21.

Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands

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http://dx.doi.org/10.1128/IAI.00077-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529651PMC
June 2019

Interacting, Nonspecific, Immunological Effects of Bacille Calmette-Guérin and Tetanus-diphtheria-pertussis Inactivated Polio Vaccinations: An Explorative, Randomized Trial.

Clin Infect Dis 2020 01;70(3):455-463

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/cid/ciz246DOI Listing
January 2020

Limited Innovations After More Than 65 Years of Immunoglobulin Replacement Therapy: Potential of IgA- and IgM-Enriched Formulations to Prevent Bacterial Respiratory Tract Infections.

Front Immunol 2018 23;9:1925. Epub 2018 Aug 23.

Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Nijmegen, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2018.01925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115500PMC
September 2019

Short-Term Hypoxia Dampens Inflammation in vivo via Enhanced Adenosine Release and Adenosine 2B Receptor Stimulation.

EBioMedicine 2018 Jul 4;33:144-156. Epub 2018 Jul 4.

Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, the Netherlands; Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.06.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085583PMC
July 2018

Selective Inhibition of Sialic Acid-Based Molecular Mimicry in Haemophilus influenzae Abrogates Serum Resistance.

Cell Chem Biol 2018 10 5;25(10):1279-1285.e8. Epub 2018 Jul 5.

Cluster of Molecular Chemistry, Institute for Molecules and Materials, Radboud University, Nijmegen 6525 AJ, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2018.05.018DOI Listing
October 2018

Streptococcus pneumoniae PspC Subgroup Prevalence in Invasive Disease and Differences in Contribution to Complement Evasion.

Infect Immun 2018 04 22;86(4). Epub 2018 Mar 22.

Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands

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http://dx.doi.org/10.1128/IAI.00010-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865030PMC
April 2018

IgM Augments Complement Bactericidal Activity with Serum from a Patient with a Novel CD79a Mutation.

J Clin Immunol 2018 02 15;38(2):185-192. Epub 2018 Jan 15.

Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s10875-017-0474-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840230PMC
February 2018

Spleen-derived IFN-γ induces generation of PD-L1-suppressive neutrophils during endotoxemia.

J Leukoc Biol 2017 12 3;102(6):1401-1409. Epub 2017 Oct 3.

Radboud Center for Infectious Diseases (RCI), Nijmegen, The Netherlands; and

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http://doi.wiley.com/10.1189/jlb.3A0217-051RR
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http://dx.doi.org/10.1189/jlb.3A0217-051RRDOI Listing
December 2017

Genetic background impacts vaccine-induced reduction of pneumococcal colonization.

Vaccine 2017 09 17;35(39):5235-5241. Epub 2017 Aug 17.

Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud University Medical Center, Radboud Center for Infectious Diseases, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2017.08.023DOI Listing
September 2017

Metabolic Oligosaccharide Engineering with Alkyne Sialic Acids Confers Neuraminidase Resistance and Inhibits Influenza Reproduction.

Bioconjug Chem 2017 07 27;28(7):1811-1815. Epub 2017 Jun 27.

Laboratory of Pediatric Infectious Diseases, Radboud Center for Infectious Diseases, Radboudumc , Geert Grooteplein Zuid 32, 6525 GA Nijmegen, The Netherlands.

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http://dx.doi.org/10.1021/acs.bioconjchem.7b00224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520103PMC
July 2017

A versatile assay to determine bacterial and host factors contributing to opsonophagocytotic killing in hirudin-anticoagulated whole blood.

Sci Rep 2017 02 8;7:42137. Epub 2017 Feb 8.

Laboratory of Pediatric Infectious Diseases, Radboud Center for Infectious Diseases, Radboud university medical center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/srep42137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296863PMC
February 2017

Bacterial Lysis through Interference with Peptidoglycan Synthesis Increases Biofilm Formation by Nontypeable .

mSphere 2017 Jan-Feb;2(1). Epub 2017 Jan 18.

Laboratory of Pediatric Infectious Diseases, Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1128/mSphere.00329-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244263PMC
January 2017

Alternative pathway regulation by factor H modulates Streptococcus pneumoniae induced proinflammatory cytokine responses by decreasing C5a receptor crosstalk.

Cytokine 2016 12 6;88:281-286. Epub 2016 Oct 6.

Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud Institute for Molecular Life Sciences, Radboudumc, 6525 GA Nijmegen, The Netherlands; Pediatric Infectious Diseases and Immunology, Department of Pediatrics, Radboudumc, 6525 GA Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2016.09.025DOI Listing
December 2016

Complement Factor H Serum Levels Determine Resistance to Pneumococcal Invasive Disease.

J Infect Dis 2016 06 21;213(11):1820-7. Epub 2016 Jan 21.

Laboratory of Pediatric Infectious Diseases Division of Pediatric Infectious Diseases and Immunology, Department of Pediatrics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/infdis/jiw029DOI Listing
June 2016

From microbial gene essentiality to novel antimicrobial drug targets.

BMC Genomics 2014 Nov 5;15:958. Epub 2014 Nov 5.

Radboud Institute for Molecular Life Sciences, Laboratory of Paediatric Infectious Diseases, Radboud University Medical Centre, Nijmegen 6500 HB, The Netherlands.

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http://dx.doi.org/10.1186/1471-2164-15-958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233050PMC
November 2014

Increased biofilm formation by nontypeable Haemophilus influenzae isolates from patients with invasive disease or otitis media versus strains recovered from cases of respiratory infections.

Appl Environ Microbiol 2014 Nov 5;80(22):7088-95. Epub 2014 Sep 5.

Microbiology Department, Hospital Universitari Bellvitge, IDIBELL-Universitat de Barcelona, Barcelona, Spain Research Network for Respiratory Diseases (CIBERES), ISCIII, Madrid, Spain

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http://dx.doi.org/10.1128/AEM.02544-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249015PMC
November 2014

Variable processing of the IgA protease autotransporter at the cell surface of Neisseria meningitidis.

Microbiology (Reading) 2014 Nov 26;160(Pt 11):2421-2431. Epub 2014 Aug 26.

Department of Molecular Microbiology, Institute of Molecular Cell Biology, VU University, 1081 HV Amsterdam, The Netherlands.

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http://dx.doi.org/10.1099/mic.0.082511-0DOI Listing
November 2014

Binding of human factor H to outer membrane protein P5 of non-typeable Haemophilus influenzae contributes to complement resistance.

Mol Microbiol 2014 Oct 18;94(1):89-106. Epub 2014 Aug 18.

Department of Microbiology, University of Pennsylvania, Philadelphia, PA, USA; Department of Pediatrics, Laboratory of Pediatric Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1111/mmi.12741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497536PMC
October 2014

Shielding of a lipooligosaccharide IgM epitope allows evasion of neutrophil-mediated killing of an invasive strain of nontypeable Haemophilus influenzae.

mBio 2014 Jul 22;5(4):e01478-14. Epub 2014 Jul 22.

Department of Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1128/mBio.01478-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120200PMC
July 2014

Neutrophil integrin affinity regulation in adhesion, migration, and bacterial clearance.

Cell Adh Migr 2013 Nov-Dec;7(6):476-81. Epub 2013 Dec 2.

Department of Microbiology; University of Pennsylvania; Philadelphia, PA USA.

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http://dx.doi.org/10.4161/cam.27293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916351PMC
September 2014

Physiological concentrations of leptin do not affect human neutrophils.

PLoS One 2013 16;8(9):e73170. Epub 2013 Sep 16.

Department of Respiratory Medicine, University Medical Centre Utrecht, Utrecht, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0073170PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774682PMC
May 2014

Novel concepts in nontypeable Haemophilus influenzae biofilm formation.

FEMS Microbiol Lett 2013 Sep 15;346(2):81-9. Epub 2013 Jul 15.

Laboratory of Pediatric Infectious Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1111/1574-6968.12203DOI Listing
September 2013

Modulation of granulocyte kinetics by GM-CSF/IFN-γ in a human LPS rechallenge model.

J Leukoc Biol 2013 Sep 21;94(3):513-20. Epub 2013 Jun 21.

Department of Respiratory Medicine, University Medical Centre Utrecht, The Netherlands.

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http://dx.doi.org/10.1189/jlb.0213066DOI Listing
September 2013

Resistance to complement-mediated killing and IgM binding to non-typeable Haemophilus influenzae is not altered when ascending from the nasopharynx to the middle ears in children with otitis media.

Med Microbiol Immunol 2013 Dec 18;202(6):407-15. Epub 2013 Jun 18.

Laboratory of Pediatric Infectious Diseases, Radboud University Medical Centre, Internal Post 224, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands,

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http://dx.doi.org/10.1007/s00430-013-0302-5DOI Listing
December 2013

Gelsolin expression increases β1 -integrin affinity and L1210 cell adhesion.

Cytoskeleton (Hoboken) 2013 Jul 10;70(7):385-93. Epub 2013 May 10.

Department of Respiratory Medicine, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1002/cm.21112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074084PMC
July 2013

Nontypeable Haemophilus influenzae carbonic anhydrase is important for environmental and intracellular survival.

J Bacteriol 2013 Jun 5;195(12):2737-46. Epub 2013 Apr 5.

Laboratory of Pediatric Infectious Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1128/JB.01870-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697255PMC
June 2013

Genetic requirements for Moraxella catarrhalis growth under iron-limiting conditions.

Mol Microbiol 2013 Jan 19;87(1):14-29. Epub 2012 Nov 19.

Laboratory of Pediatric Infectious Diseases, Radboud University Medical Centre, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1111/mmi.12081DOI Listing
January 2013

A unique protein profile of peripheral neutrophils from COPD patients does not reflect cytokine-induced protein profiles of neutrophils in vitro.

BMC Pulm Med 2011 Sep 6;11:44. Epub 2011 Sep 6.

Department of Respiratory Medicine, University Medical Center, Heidelberglaan 100, 3584 CX Utrecht, the Netherlands.

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http://dx.doi.org/10.1186/1471-2466-11-44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176249PMC
September 2011

GM-CSF and TNFα modulate protein expression of human neutrophils visualized by fluorescence two-dimensional difference gel electrophoresis.

Cytokine 2011 Nov 27;56(2):422-9. Epub 2011 Aug 27.

Department of Respiratory Medicine, University Medical Center Utrecht, Heidelberglaan 100, 3584CX Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.cyto.2011.06.025DOI Listing
November 2011

Abrogation of NF-κB signaling in human neutrophils induces neutrophil survival through sustained p38-MAPK activation.

J Leukoc Biol 2010 Oct 23;88(4):655-64. Epub 2010 Jun 23.

Department of Respiratory Medicine, University Medical Center, Utrecht, The Netherlands.

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http://dx.doi.org/10.1189/jlb.0809544DOI Listing
October 2010

A 2D-DIGE approach to identify proteins involved in inside-out control of integrins.

J Proteome Res 2009 Aug;8(8):3824-33

Department of Respiratory Medicine, University Medical Center, Utrecht, The Netherlands.

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http://dx.doi.org/10.1021/pr8010815DOI Listing
August 2009

Functional antagonism by GM-CSF on TNF-alpha-induced CD83 expression in human neutrophils.

Mol Immunol 2008 Nov 27;46(1):91-6. Epub 2008 Aug 27.

Department of Respiratory Medicine, University Medical Center Utrecht (UMCU), Heidelberglaan 100, 3584CX Utrecht, Netherlands.

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http://dx.doi.org/10.1016/j.molimm.2008.07.006DOI Listing
November 2008