Jeroen A A Demmers

Jeroen A A Demmers

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Jeroen A A Demmers

Jeroen A A Demmers

Publications by authors named "Jeroen A A Demmers"

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Global Proteome and Ubiquitinome Changes in the Soluble and Insoluble Fractions of Q175 Huntington Mice Brains.

Mol Cell Proteomics 2019 Sep 28;18(9):1705-1720. Epub 2019 May 28.

‡Department of Medical Biology, Amsterdam UMC, location AMC, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands

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http://dx.doi.org/10.1074/mcp.RA119.001486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731087PMC
September 2019

Myosin V regulates synaptopodin clustering and localization in the dendrites of hippocampal neurons.

J Cell Sci 2019 Aug 22;132(16). Epub 2019 Aug 22.

DFG Emmy Noether Group 'Neuronal Protein Transport', Center for Molecular Neurobiology, ZMNH, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany

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http://dx.doi.org/10.1242/jcs.230177DOI Listing
August 2019

FACT subunit Spt16 controls UVSSA recruitment to lesion-stalled RNA Pol II and stimulates TC-NER.

Nucleic Acids Res 2019 May;47(8):4011-4025

Department of Molecular Genetics, Oncode Institute, Erasmus MC, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands.

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http://dx.doi.org/10.1093/nar/gkz055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486547PMC
May 2019

Identifying cystogenic paracrine signaling molecules in cyst fluid of patients with polycystic kidney disease.

Am J Physiol Renal Physiol 2019 Jan 7;316(1):F204-F213. Epub 2018 Nov 7.

Department of Internal Medicine, Division of Nephrology and Transplantation, Erasmus Medical Center, Rotterdam , The Netherlands.

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https://www.physiology.org/doi/10.1152/ajprenal.00470.2018
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http://dx.doi.org/10.1152/ajprenal.00470.2018DOI Listing
January 2019

Improvement of ubiquitylation site detection by Orbitrap mass spectrometry.

J Proteomics 2018 02 6;172:49-56. Epub 2017 Nov 6.

Proteomics Center, Erasmus University Medical Center, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2017.10.014DOI Listing
February 2018

Quantitative Proteomics Reveals Extensive Changes in the Ubiquitinome after Perturbation of the Proteasome by Targeted dsRNA-Mediated Subunit Knockdown in Drosophila.

J Proteome Res 2017 08 11;16(8):2848-2862. Epub 2017 Jul 11.

Proteomics Center, ‡Netherlands Proteomics Center, and §Department of Biochemistry, Erasmus University Medical Center , Wytemaweg 80, 3015 CN Rotterdam, The Netherlands.

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http://dx.doi.org/10.1021/acs.jproteome.7b00156DOI Listing
August 2017

Proteomic profiling of the spinal cord in ALS: decreased ATP5D levels suggest synaptic dysfunction in ALS pathogenesis.

Amyotroph Lateral Scler Frontotemporal Degener 2017 05 29;18(3-4):210-220. Epub 2016 Nov 29.

h Department of Neurology and Neurosurgery , Brain Centre Rudolf Magnus, University Medical Centre Utrecht , Utrecht , The Netherlands.

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http://dx.doi.org/10.1080/21678421.2016.1245757DOI Listing
May 2017

Combgap contributes to recruitment of Polycomb group proteins in Drosophila.

Proc Natl Acad Sci U S A 2016 Apr 21;113(14):3826-31. Epub 2016 Mar 21.

Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892;

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http://dx.doi.org/10.1073/pnas.1520926113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833261PMC
April 2016

Elevated Plasma Cardiac Troponin T Levels Caused by Skeletal Muscle Damage in Pompe Disease.

Circ Cardiovasc Genet 2016 Feb 19;9(1):6-13. Epub 2016 Jan 19.

From the Department of Neurology (S.C.A.W., E.B., P.A.v.D.), Center for Lysosomal and Metabolic Diseases (S.C.A.W., G.J.S., M.E.K., T.J.M.v.G., S.G., J.P., E.B., A.T.v.d.P., P.A.v.D., W.W.M.P.P.), Molecular Stem Cell Biology, Department of Clinical Genetics (G.J.S., T.J.M.v.G., S.G., J.P., W.W.M.P.P.), Department of Cardiology (M.M.), Department of Clinical Chemistry (R.H.N.v.S.), Erasmus MC University Medical Center, Rotterdam, The Netherlands; Division of Metabolic Diseases and Genetics, Department of Pediatrics, Erasmus MC-Sophia, Rotterdam, The Netherlands (G.J.S., T.J.M.v.G., S.G., J.P., A.T.v.d.P., W.W.M.P.P.); Proteomics Center, Erasmus MC University Medical Center, Rotterdam, The Netherlands (D.H.W.D., J.A.A.D.); Netherlands Proteomics Center, Rotterdam, The Netherlands (D.H.W.D., J.A.A.D.); and NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands (L.B.V.).

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http://dx.doi.org/10.1161/CIRCGENETICS.115.001322DOI Listing
February 2016

Identification of the (Pro)renin Receptor as a Novel Regulator of Low-Density Lipoprotein Metabolism.

Circ Res 2016 Jan 18;118(2):222-9. Epub 2015 Nov 18.

From the Astra Zeneca-Shenzhen University Joint Institute of Nephrology, Shenzhen University Medical Center, Shenzhen University, Shenzhen, China (X.L.); Division of Pharmacology and Vascular Medicine, Department of Internal Medicine (X.L., M.E.M., M.T.M., A.H.J.D.) and Proteomics Center (D.H.W.D., J.A.A.D.), Erasmus Medical Center, Rotterdam, The Netherlands; and Department of Medical Biochemistry (X.L., J.K.N., V.S., A.L., S.S., N.Z.) and Laboratory of Experimental Vascular Medicine (G.M.D-.T.), Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1161/CIRCRESAHA.115.306799DOI Listing
January 2016

Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases.

Dev Cell 2015 Dec;35(5):537-552

Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, 3584 CG Utrecht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2015.11.008DOI Listing
December 2015

Identification of protein receptors for coronaviruses by mass spectrometry.

Methods Mol Biol 2015 ;1282:165-82

Department of Viroscience, Erasmus Medical Center, 2040, Rotterdam, CA, 3000, The Netherlands.

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http://dx.doi.org/10.1007/978-1-4939-2438-7_15DOI Listing
November 2015

Integrative analysis of genomics and proteomics data on clinical breast cancer tissue specimens extracted with acid guanidinium thiocyanate-phenol-chloroform.

J Proteome Res 2015 Mar 2;14(3):1627-36. Epub 2015 Feb 2.

Department of Medical Oncology, Erasmus MC Cancer Institute, University Medical Center Rotterdam , Be401, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1021/acs.jproteome.5b00046DOI Listing
March 2015

Global quantitative proteomics reveals novel factors in the ecdysone signaling pathway in Drosophila melanogaster.

Proteomics 2015 Feb 14;15(4):725-38. Epub 2015 Jan 14.

Proteomics Center, Erasmus University Medical Center, Rotterdam, The Netherlands; Netherlands Proteomics Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/pmic.201400308DOI Listing
February 2015

Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.

FASEB J 2015 Jan 30;29(1):274-85. Epub 2014 Oct 30.

Department of Internal Medicine and Erasmus MC Stem Cell and Regenerative Medicine Institute,

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http://dx.doi.org/10.1096/fj.14-261404DOI Listing
January 2015

NLS-tagging: an alternative strategy to tag nuclear proteins.

Nucleic Acids Res 2014 Dec 26;42(21). Epub 2014 Sep 26.

Department of Cell Biology, Erasmus Medical Center, Faculty building, PO Box 2040, 3000 CA Rotterdam, The Netherlands Center for Biomedical Genetics and Medical Epigenetics Consortium, Erasmus Medical Center, Faculty building, PO Box 2040, 3000 CA Rotterdam, The Netherlands Center for Biomedical Genetics, Erasmus Medical Center, Faculty building, PO Box 2040, 3000 CA Rotterdam, The Netherlands

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http://dx.doi.org/10.1093/nar/gku869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245968PMC
December 2014

Nucleotide biosynthetic enzyme GMP synthase is a TRIM21-controlled relay of p53 stabilization.

Mol Cell 2014 Feb 23;53(3):458-70. Epub 2014 Jan 23.

Department of Biochemistry and Centre for Biomedical Genetics, Erasmus University Medical Centre, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2013.12.017DOI Listing
February 2014

ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN.

Hum Mol Genet 2013 Sep 15;22(18):3690-704. Epub 2013 May 15.

Department of Neuroscience and Pharmacology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/hmg/ddt222DOI Listing
September 2013

An immunoaffinity purification method for the proteomic analysis of ubiquitinated protein complexes.

Anal Biochem 2013 Sep 3;440(2):227-36. Epub 2013 Jun 3.

Department of Genetics and Netherlands Proteomics Centre, Centre for Biomedical Genetics, Erasmus University Medical Centre, 3015 GE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ab.2013.05.020DOI Listing
September 2013

Subunits of the histone chaperone CAF1 also mediate assembly of protamine-based chromatin.

Cell Rep 2013 Jul 27;4(1):59-65. Epub 2013 Jun 27.

Department of Biochemistry, Erasmus University Medical Centre, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.celrep.2013.06.002DOI Listing
July 2013

Identification of fibrin clot-bound plasma proteins.

PLoS One 2012 3;7(8):e41966. Epub 2012 Aug 3.

Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0041966PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411686PMC
February 2013

UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair.

Nat Genet 2012 May;44(5):598-602

Department of Genetics and Netherlands Proteomics Centre, Centre for Biomedical Genetics, Erasmus Medical Centre, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/ng.2230DOI Listing
May 2012

Transcription-independent function of Polycomb group protein PSC in cell cycle control.

Science 2012 May 5;336(6082):744-7. Epub 2012 Apr 5.

Department of Biochemistry and Centre for Biomedical Genetics, Erasmus University Medical Centre, Post Office Box 1738, 3000 DR, Rotterdam, Netherlands.

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http://dx.doi.org/10.1126/science.1215927DOI Listing
May 2012

Proteomic analysis of the microenvironment of developing oocytes.

Proteomics 2012 May;12(9):1463-71

Department of Obstetrics and Gynecology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/pmic.201100240DOI Listing
May 2012

VEGFR2 translocates to the nucleus to regulate its own transcription.

PLoS One 2011 28;6(9):e25668. Epub 2011 Sep 28.

Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0025668PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182252PMC
January 2012

Unraveling the human bone microenvironment beyond the classical extracellular matrix proteins: a human bone protein library.

J Proteome Res 2011 Oct 21;10(10):4725-33. Epub 2011 Sep 21.

Department of Internal Medicine, Erasmus Medical Centre, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1021/pr200522nDOI Listing
October 2011

Drosophila transcription factor Tramtrack69 binds MEP1 to recruit the chromatin remodeler NuRD.

Mol Cell Biol 2010 Nov 23;30(21):5234-44. Epub 2010 Aug 23.

Department of Biochemistry, Center for Biomedical Genetics, Erasmus University Medical Center, Rotterdam, Netherlands.

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http://dx.doi.org/10.1128/MCB.00266-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953047PMC
November 2010

Differential proteomics based on 18O labeling to determine the cyclin dependent kinase 9 interactome.

J Proteome Res 2010 Sep;9(9):4464-75

Proteomics Center and Department of Cell Biology, Erasmus University Medical Center, Dr. Molewaterplein 50, 3015 GE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1021/pr100217dDOI Listing
September 2010

Histone chaperones ASF1 and NAP1 differentially modulate removal of active histone marks by LID-RPD3 complexes during NOTCH silencing.

Mol Cell 2009 Sep;35(6):782-93

Department of Biochemistry, Center for Biomedical Genetics, Erasmus University Medical Center, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S109727650900516
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http://dx.doi.org/10.1016/j.molcel.2009.07.020DOI Listing
September 2009

DNA dependent recruitment of DDX17 and other interacting proteins by the human androgen receptor.

Biochim Biophys Acta 2009 Feb 14;1794(2):193-8. Epub 2008 Nov 14.

Department of Reproduction and Development, Erasmus MC, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.bbapap.2008.11.001DOI Listing
February 2009

dKDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing.

Genes Dev 2008 Oct;22(20):2799-810

Department of Biochemistry, Center for Biomedical Genetics, Erasmus University Medical Center, 3000 DR Rotterdam, The Netherlands.

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http://dx.doi.org/10.1101/gad.484208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569881PMC
October 2008

The transcriptional coactivator SAYP is a trithorax group signature subunit of the PBAP chromatin remodeling complex.

Mol Cell Biol 2008 May 25;28(9):2920-9. Epub 2008 Feb 25.

Department of Biochemistry, Center for Biomedical Genetics, Erasmus University Medical Center, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands.

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http://dx.doi.org/10.1128/MCB.02217-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2293093PMC
May 2008

Deubiquitylating enzyme UBP64 controls cell fate through stabilization of the transcriptional repressor tramtrack.

Mol Cell Biol 2008 Mar 26;28(5):1606-15. Epub 2007 Dec 26.

Department of Biochemistry, Erasmus University Medical Center, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands.

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http://dx.doi.org/10.1128/MCB.01567-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258761PMC
March 2008

Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor.

Mol Cell Proteomics 2007 May 11;6(5):820-34. Epub 2007 Feb 11.

Department of Developmental and Cell Biology, Centro de Investigaciones Biológicas (CSIC), Ramiro de Maeztu 9, 28040 Madrid, Spain.

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http://dx.doi.org/10.1074/mcp.M600275-MCP200DOI Listing
May 2007

Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4.

Proc Natl Acad Sci U S A 2006 Dec 21;103(49):18597-602. Epub 2006 Nov 21.

Department of Biochemistry, Center for Biomics, Erasmus MC, University Medical Center, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1073/pnas.0609061103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1693708PMC
December 2006

Mass spectrometric identification of human prostate cancer-derived proteins in serum of xenograft-bearing mice.

Mol Cell Proteomics 2006 Oct 19;5(10):1830-9. Epub 2006 May 19.

Department of Urology, Josephine Nefkens Institute, Erasmus MC, 3000 DR, Rotterdam, The Netherlands.

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http://www.mcponline.org/lookup/doi/10.1074/mcp.M500371-MCP2
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http://dx.doi.org/10.1074/mcp.M500371-MCP200DOI Listing
October 2006

Photo-crosslinking analysis of preferential interactions between a transmembrane peptide and matching lipids.

Biochemistry 2004 Apr;43(15):4482-9

Department of Biochemistry of Membranes, Center for Biomembranes and Lipid Enzymology, Institute of Biomembranes, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.

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http://dx.doi.org/10.1021/bi049899dDOI Listing
April 2004

Interfacial anchor properties of tryptophan residues in transmembrane peptides can dominate over hydrophobic matching effects in peptide-lipid interactions.

Biochemistry 2003 May;42(18):5341-8

Department of Biochemistry of Membranes, Center for Biomembranes and Lipid Enzymology, Institute of Biomembranes, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.

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http://dx.doi.org/10.1021/bi027000rDOI Listing
May 2003

Interaction of the K+ channel KcsA with membrane phospholipids as studied by ESI mass spectrometry.

FEBS Lett 2003 Apr;541(1-3):28-32

Department of Biochemistry of Membranes, Center for Biomembranes and Lipid Enzymology, Institute of Biomembranes, Utrecht University, The Netherlands.

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http://dx.doi.org/10.1016/s0014-5793(03)00282-5DOI Listing
April 2003

Factors affecting gas-phase deuterium scrambling in peptide ions and their implications for protein structure determination.

J Am Chem Soc 2002 Sep;124(37):11191-8

Contribution from the Department of Biomolecular Mass Spectrometry, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Sorbonnelaan 16, 3584 CA Utrecht, The Netherlands.

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http://dx.doi.org/10.1021/ja0125927DOI Listing
September 2002