Jernej Ule

Jernej Ule

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Jernej Ule

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Author Correction: Regulatory feedback from nascent RNA to chromatin and transcription.

Nat Rev Mol Cell Biol 2019 Sep 10. Epub 2019 Sep 10.

UCL Cancer Institute, University College London, 72 Huntley Street, London, WC1E 6BT, UK.

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http://dx.doi.org/10.1038/s41580-019-0174-7DOI Listing
September 2019

FICC-Seq: a method for enzyme-specified profiling of methyl-5-uridine in cellular RNA.

Nucleic Acids Res 2019 Jul 30. Epub 2019 Jul 30.

Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK.

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http://dx.doi.org/10.1093/nar/gkz658DOI Listing
July 2019

The Transcriptome-wide Landscape and Modalities of EJC Binding in Adult Drosophila.

Cell Rep 2019 Jul;28(5):1219-1236.e11

European Molecular Biology Laboratory, 69117 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.06.088DOI Listing
July 2019

Charting DENR-dependent translation reinitiation uncovers predictive uORF features and links to circadian timekeeping via Clock.

Nucleic Acids Res 2019 Jun;47(10):5193-5209

Center for Integrative Genomics, University of Lausanne, Genopode, 1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1093/nar/gkz261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547434PMC
June 2019

Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition.

Mol Cell 2019 Jun 29;74(5):951-965.e13. Epub 2019 Apr 29.

Institute of Stem Cell Research, Helmholtz Zentrum München, 85764 Neuherberg, Germany; Comprehensive Pneumology Center (CPC-M), Ludwig-Maximilians-Universität München, Asklepios Fachkliniken München-Gauting und Helmholtz Zentrum München, Max-Lebsche-Platz 31, 81377 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.03.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561722PMC
June 2019

The origin of neural microexons.

Nat Ecol Evol 2019 04;3(4):526-527

The Francis Crick Institute, London, UK.

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http://dx.doi.org/10.1038/s41559-019-0818-1DOI Listing
April 2019

Genomic Accumulation of Retrotransposons Was Facilitated by Repressive RNA-Binding Proteins: A Hypothesis.

Bioessays 2019 02 1;41(2):e1800132. Epub 2019 Feb 1.

Dr. J. Attig, Prof. J. Ule, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.

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http://dx.doi.org/10.1002/bies.201800132DOI Listing
February 2019

Exon Junction Complex Shapes the Transcriptome by Repressing Recursive Splicing.

Mol Cell 2018 11;72(3):496-509.e9

Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10972765183083
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http://dx.doi.org/10.1016/j.molcel.2018.09.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224609PMC
November 2018

The Future of Cross-Linking and Immunoprecipitation (CLIP).

Cold Spring Harb Perspect Biol 2018 08 1;10(8). Epub 2018 Aug 1.

Laboratory of Molecular Neuro-Oncology, The Rockefeller University, New York, New York 10065.

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http://dx.doi.org/10.1101/cshperspect.a032243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071486PMC
August 2018

Heteromeric RNP Assembly at LINEs Controls Lineage-Specific RNA Processing.

Cell 2018 08 2;174(5):1067-1081.e17. Epub 2018 Aug 2.

The Francis Crick Institute, Midland Road 1, Kings Cross, London NW1 1AT, UK; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108849PMC
August 2018

'Read-through marking' reveals differential nucleotide composition of read-through and truncated cDNAs in iCLIP.

Wellcome Open Res 2018 22;3:77. Epub 2018 Jun 22.

Department of Molecular Neuroscience, UCL Institute of Neurology, London, WC1N 3BG, UK.

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http://dx.doi.org/10.12688/wellcomeopenres.14663.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051193PMC
June 2018

No way out: when RNA elements promote nuclear retention.

EMBO J 2018 03 27;37(6). Epub 2018 Feb 27.

The Francis Crick Institute, London, UK.

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http://dx.doi.org/10.15252/embj.201899123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852650PMC
March 2018

Illustrating the Epitranscriptome at Nucleotide Resolution Using Methylation-iCLIP (miCLIP).

Methods Mol Biol 2017 ;1562:91-106

Department of Biology and Biochemistry, University of Bath, Bath, BA2 7AY, UK.

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http://dx.doi.org/10.1007/978-1-4939-6807-7_7DOI Listing
February 2018

Advances in CLIP Technologies for Studies of Protein-RNA Interactions.

Mol Cell 2018 02;69(3):354-369

Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2018.01.005DOI Listing
February 2018

Tia1 dependent regulation of mRNA subcellular location and translation controls p53 expression in B cells.

Nat Commun 2017 09 13;8(1):530. Epub 2017 Sep 13.

Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge, CB22 3AT, UK.

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http://dx.doi.org/10.1038/s41467-017-00454-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597594PMC
September 2017

Regulatory feedback from nascent RNA to chromatin and transcription.

Nat Rev Mol Cell Biol 2017 05 8;18(5):331-337. Epub 2017 Mar 8.

UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6BT, UK.

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http://www.nature.com/articles/nrm.2017.12
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http://dx.doi.org/10.1038/nrm.2017.12DOI Listing
May 2017

High-Resolution RNA Maps Suggest Common Principles of Splicing and Polyadenylation Regulation by TDP-43.

Cell Rep 2017 05;19(5):1056-1067

MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK; UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.04.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437728PMC
May 2017

Using hiCLIP to identify RNA duplexes that interact with a specific RNA-binding protein.

Nat Protoc 2017 03 23;12(3):611-637. Epub 2017 Feb 23.

Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1038/nprot.2016.188DOI Listing
March 2017

Major Shifts in Glial Regional Identity Are a Transcriptional Hallmark of Human Brain Aging.

Cell Rep 2017 01;18(2):557-570

Institute of Neurology, University College London, London WC1N 3BG, UK; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.12.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5263238PMC
January 2017

Insights into the design and interpretation of iCLIP experiments.

Genome Biol 2017 01 16;18(1). Epub 2017 Jan 16.

Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1186/s13059-016-1130-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240381PMC
January 2017

Splicing repression allows the gradual emergence of new Alu-exons in primate evolution.

Elife 2016 11 18;5. Epub 2016 Nov 18.

Department of Molecular Neuroscience, UCL Institute of Neurology, London, United Kingdom.

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http://dx.doi.org/10.7554/eLife.19545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115870PMC
November 2016

Lessons from non-canonical splicing.

Nat Rev Genet 2016 07 31;17(7):407-421. Epub 2016 May 31.

Department of Molecular Neuroscience, UCL Institute of Neurology, Russell Square House, Russell Square, London, WC1B 5EH, UK.

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http://dx.doi.org/10.1038/nrg.2016.46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154377PMC
July 2016

Orthogonal matrix factorization enables integrative analysis of multiple RNA binding proteins.

Bioinformatics 2016 05 18;32(10):1527-35. Epub 2016 Jan 18.

University of Ljubljana, Faculty of Computer and Information Science, Ljubljana, SI 1000, Slovenia.

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http://dx.doi.org/10.1093/bioinformatics/btw003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894278PMC
May 2016

Matrin3: connecting gene expression with the nuclear matrix.

Wiley Interdiscip Rev RNA 2016 05 26;7(3):303-15. Epub 2016 Jan 26.

Department of Biochemistry, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1002/wrna.1336DOI Listing
May 2016

Intergenic Alu exonisation facilitates the evolution of tissue-specific transcript ends.

Nucleic Acids Res 2015 Dec 22;43(21):10492-505. Epub 2015 Sep 22.

MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK Institute of Molecular Biology (IMB) gGmbH, Ackermannweg 4, 55128 Mainz, Germany Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK

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http://dx.doi.org/10.1093/nar/gkv956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666398PMC
December 2015

iCLIP identifies novel roles for SAFB1 in regulating RNA processing and neuronal function.

BMC Biol 2015 Dec 22;13:111. Epub 2015 Dec 22.

Regenerative Medicine Laboratories, School of Clinical Sciences, Cellular & Molecular Medicine, Medical Sciences Building, University Walk, University of Bristol, Bristol, BS8 1TD, UK.

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http://dx.doi.org/10.1186/s12915-015-0220-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689037PMC
December 2015

RNA-Binding Protein Musashi1 Is a Central Regulator of Adhesion Pathways in Glioblastoma.

Mol Cell Biol 2015 Sep 22;35(17):2965-78. Epub 2015 Jun 22.

Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA

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http://dx.doi.org/10.1128/MCB.00410-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525321PMC
September 2015

Recursive splicing in long vertebrate genes.

Nature 2015 May 13;521(7552):371-375. Epub 2015 May 13.

Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1038/nature14466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471124PMC
May 2015

Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.

Genes Dev 2015 Mar;29(5):501-12

Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA; Division of Newborn Medicine, Boston Children's Hospital, Boston, Massachusetts 02115, USA;

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http://dx.doi.org/10.1101/gad.258483.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358403PMC
March 2015

hiCLIP reveals the in vivo atlas of mRNA secondary structures recognized by Staufen 1.

Nature 2015 Mar 18;519(7544):491-4. Epub 2015 Mar 18.

1] MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK [2] Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.

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http://www.nature.com/articles/nature14280
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http://dx.doi.org/10.1038/nature14280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376666PMC
March 2015

Promiscuous RNA binding ensures effective encapsidation of APOBEC3 proteins by HIV-1.

PLoS Pathog 2015 Jan 15;11(1):e1004609. Epub 2015 Jan 15.

Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom.

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http://dx.doi.org/10.1371/journal.ppat.1004609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295846PMC
January 2015

CPSF30 and Wdr33 directly bind to AAUAAA in mammalian mRNA 3' processing.

Genes Dev 2014 Nov 9;28(21):2370-80. Epub 2014 Oct 9.

Department of Microbiology and Molecular Genetics, School of Medicine, University of California at Irvine, Irvine, California 92697, USA;

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http://dx.doi.org/10.1101/gad.250993.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215182PMC
November 2014

The coilin interactome identifies hundreds of small noncoding RNAs that traffic through Cajal bodies.

Mol Cell 2014 Nov 6;56(3):389-99. Epub 2014 Nov 6.

Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany; Department of Molecular Biophysics & Biochemistry, Yale University, 333 Cedar Street, New Haven, CT 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2014.10.004DOI Listing
November 2014

A global regulatory mechanism for activating an exon network required for neurogenesis.

Mol Cell 2014 Oct 11;56(1):90-103. Epub 2014 Sep 11.

Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2014.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608043PMC
October 2014

3' UTR length and messenger ribonucleoprotein composition determine endocleavage efficiencies at termination codons.

Cell Rep 2014 Oct 9;9(2):555-68. Epub 2014 Oct 9.

Institute for Genetics, University of Cologne, 50674 Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.09.012DOI Listing
October 2014

iCLIP: protein-RNA interactions at nucleotide resolution.

Methods 2014 Feb 25;65(3):274-87. Epub 2013 Oct 25.

Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2013.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988997PMC
February 2014

'Oming in on RNA-protein interactions.

Genome Biol 2014 Jan 31;15(1):401. Epub 2014 Jan 31.

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http://dx.doi.org/10.1186/gb4158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053986PMC
January 2014

Molecular basis of UG-rich RNA recognition by the human splicing factor TDP-43.

Nat Struct Mol Biol 2013 Dec 17;20(12):1443-9. Epub 2013 Nov 17.

1] Central European Institute of Technology, Masaryk University, Brno, Czech Republic. [2] Institute of Molecular Biology and Biophysics, Eidgenössische Technische Hochschule Hönggerberg, Zürich, Switzerland.

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http://dx.doi.org/10.1038/nsmb.2698DOI Listing
December 2013

What, where, and when: the importance of post-transcriptional regulation in the brain.

Front Neurosci 2013 29;7:192. Epub 2013 Oct 29.

Department for Anatomy and Cell Biology, Ludwig Maximilian University Munich, Germany.

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http://journal.frontiersin.org/article/10.3389/fnins.2013.00
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http://dx.doi.org/10.3389/fnins.2013.00192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810603PMC
November 2013

Requirement of heterogeneous nuclear ribonucleoprotein C for BRCA gene expression and homologous recombination.

PLoS One 2013 9;8(4):e61368. Epub 2013 Apr 9.

Department of Radiation Oncology, The Cancer Institute of New Jersey and Robert Wood Johnson Medical School, New Brunswick, New Jersey, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0061368PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621867PMC
October 2013

CLIPing the brain: studies of protein-RNA interactions important for neurodegenerative disorders.

Mol Cell Neurosci 2013 Sep 10;56:429-35. Epub 2013 Apr 10.

MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 0QH, UK; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Feodor-Lynen-Strasse 25, 81377 Munich, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S10447431130005
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http://dx.doi.org/10.1016/j.mcn.2013.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793874PMC
September 2013

NSun2-mediated cytosine-5 methylation of vault noncoding RNA determines its processing into regulatory small RNAs.

Cell Rep 2013 Jul 18;4(2):255-61. Epub 2013 Jul 18.

Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QR, UK.

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http://dx.doi.org/10.1016/j.celrep.2013.06.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730056PMC
July 2013

Perturbation of chromatin structure globally affects localization and recruitment of splicing factors.

PLoS One 2012 12;7(11):e48084. Epub 2012 Nov 12.

Laboratorio de Fisiología y Biología Molecular, Departamento de Fisiología, Biología Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Instituto de Fisiología, Biología Molecular y Neurociencias, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0048084PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495951PMC
May 2013

Aberrant sodium channel activity in the complex seizure disorder of Celf4 mutant mice.

J Physiol 2013 Jan 22;591(1):241-55. Epub 2012 Oct 22.

The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609-1500, USA.

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http://doi.wiley.com/10.1113/jphysiol.2012.240168
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http://dx.doi.org/10.1113/jphysiol.2012.240168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630783PMC
January 2013

Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing.

PLoS Genet 2012 17;8(5):e1002717. Epub 2012 May 17.

MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.plos.org/10.1371/journal.pgen.1002717
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http://dx.doi.org/10.1371/journal.pgen.1002717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355077PMC
September 2012

Using human pluripotent stem cells to study post-transcriptional mechanisms of neurodegenerative diseases.

Brain Res 2012 Jun 5;1462:129-38. Epub 2012 Jan 5.

Anne McLaren Laboratory for Regenerative Medicine, University of Cambridge, Forvie Site, Robinson Way, Cambridge, UK.

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http://dx.doi.org/10.1016/j.brainres.2011.12.057DOI Listing
June 2012

Protein-RNA interactions: new genomic technologies and perspectives.

Nat Rev Genet 2012 Jan 18;13(2):77-83. Epub 2012 Jan 18.

Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK.

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http://dx.doi.org/10.1038/nrg3141DOI Listing
January 2012

The RNA-binding protein Rrm4 is essential for efficient secretion of endochitinase Cts1.

Mol Cell Proteomics 2011 Dec 1;10(12):M111.011213. Epub 2011 Aug 1.

Heinrich-Heine University Düsseldorf, Institute for Microbiology, Düsseldorf, Germany.

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http://dx.doi.org/10.1074/mcp.M111.011213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237082PMC
December 2011

The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes.

Genes Dev 2011 Oct;25(20):2158-72

Department of Medicine, Microbiology, and Immunology, Rosalind Russell Medical Research Center, University of California at San Francisco (UCSF), USA.

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http://dx.doi.org/10.1101/gad.16962311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205586PMC
October 2011

The Neuronal Splicing Factor Nova Co-Localizes with Target RNAs in the Dendrite.

Front Neural Circuits 2010 3;4. Epub 2010 Mar 3.

Biologie Cellulaire de la Synapse Normale et Pathologique, Institut National de la Santé et de la Recherche Médicale, Ecole Normale Supérieure Paris, France.

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http://dx.doi.org/10.3389/neuro.04.005.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856630PMC
July 2011

Understanding splicing regulation through RNA splicing maps.

Trends Genet 2011 Mar 12;27(3):89-97. Epub 2011 Jan 12.

MRC Laboratory of Molecular Biology, Hills Road, Cambridge, UK, CB2 0QH.

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http://linkinghub.elsevier.com/retrieve/pii/S016895251000228
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http://dx.doi.org/10.1016/j.tig.2010.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165201PMC
March 2011

TDP-43 regulates its mRNA levels through a negative feedback loop.

EMBO J 2011 Jan 3;30(2):277-88. Epub 2010 Dec 3.

Department of Molecular Pathology, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy.

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http://dx.doi.org/10.1038/emboj.2010.310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025456PMC
January 2011

iCLIP predicts the dual splicing effects of TIA-RNA interactions.

PLoS Biol 2010 Oct 26;8(10):e1000530. Epub 2010 Oct 26.

Medical Research Council - Laboratory of Molecular Biology, Hills Road, Cambridge, United Kingdom.

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http://dx.doi.org/10.1371/journal.pbio.1000530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964331PMC
October 2010

High-throughput sequencing methods to study neuronal RNA-protein interactions.

Authors:
Jernej Ule

Biochem Soc Trans 2009 Dec;37(Pt 6):1278-80

MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK.

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http://biochemsoctrans.org/lookup/doi/10.1042/BST0371278
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http://dx.doi.org/10.1042/BST0371278DOI Listing
December 2009

CLIP: construction of cDNA libraries for high-throughput sequencing from RNAs cross-linked to proteins in vivo.

Methods 2009 Jul 9;48(3):287-93. Epub 2009 Mar 9.

MRC-Laboratory of Molecular Biology, Hills Road, Cambridge CB20QH, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S104620230900043
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http://dx.doi.org/10.1016/j.ymeth.2009.02.021DOI Listing
July 2009

HITS-CLIP yields genome-wide insights into brain alternative RNA processing.

Nature 2008 Nov 2;456(7221):464-9. Epub 2008 Nov 2.

Laboratory of Molecular Neuro-Oncology and Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/nature07488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597294PMC
November 2008

Ribonucleoprotein complexes in neurologic diseases.

Authors:
Jernej Ule

Curr Opin Neurobiol 2008 Oct 27;18(5):516-23. Epub 2008 Oct 27.

MRC Laboratory of Molecular Biology, Cambridge, UK.

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http://dx.doi.org/10.1016/j.conb.2008.09.018DOI Listing
October 2008

Functional and mechanistic insights from genome-wide studies of splicing regulation in the brain.

Adv Exp Med Biol 2007 ;623:148-60

MRC Laboratory of Molecular Biology, Cambridge, England.

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http://dx.doi.org/10.1007/978-0-387-77374-2_9DOI Listing
April 2008

Evolution of Nova-dependent splicing regulation in the brain.

PLoS Genet 2007 Oct 27;3(10):1838-47. Epub 2007 Aug 27.

Laboratory of Molecular Neuro-Oncology, The Rockefeller University, New York, New York, USA.

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http://dx.plos.org/10.1371/journal.pgen.0030173
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http://dx.doi.org/10.1371/journal.pgen.0030173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2014790PMC
October 2007