Jeremy Sanderson

Jeremy Sanderson

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Jeremy Sanderson

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Streptococcus Salivarius: A Potential Salivary Biomarker for Orofacial Granulomatosis and Crohn's Disease?

Inflamm Bowel Dis 2019 Jul;25(8):1367-1374

Department of Medical and Molecular Genetics, Faculty of Life Science and Medicine, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1093/ibd/izz022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635823PMC
July 2019

Correction of Defective T-Regulatory Cells From Patients With Crohn's Disease by Ex Vivo Ligation of Retinoic Acid Receptor-α.

Gastroenterology 2019 05 30;156(6):1775-1787. Epub 2019 Jan 30.

School of Immunology and Microbial Sciences, King's College London, London, UK; National Institute for Health Research Biomedical Research Centre, Guy's and St Thomas' NHS Trust and King's College London, London, UK. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.01.025DOI Listing
May 2019

A Case of Unusual Ileal Discoloration.

Gastroenterology 2018 07 6;155(1):e1-e2. Epub 2017 Oct 6.

Gastroenterology, Guy's and St Thomas' NHS Foundation Trust, London, UK.

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http://dx.doi.org/10.1053/j.gastro.2017.09.043DOI Listing
July 2018

Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota.

Microbiome 2018 04 20;6(1):73. Epub 2018 Apr 20.

Integrative Systems Medicine and Digestive Disease, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Exhibition Road, London, SW7 2AZ, UK.

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http://dx.doi.org/10.1186/s40168-018-0461-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909246PMC
April 2018

A practical guide to thiopurine prescribing and monitoring in IBD.

Frontline Gastroenterol 2018 Jan 29;9(1):10-15. Epub 2016 Aug 29.

Department of Gastroenterology, Guy's and St Thomas' NHS Foundation Trust, London, UK.

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http://dx.doi.org/10.1136/flgastro-2016-100738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824765PMC
January 2018

Thiopurines Dosed to a Therapeutic 6-Thioguanine Level in Combination with Adalimumab Are More Effective Than Subtherapeutic Thiopurine-based Combination Therapy or Adalimumab Monotherapy During Induction and Maintenance in Patients with Long-standing Crohn's Disease.

Inflamm Bowel Dis 2017 09;23(9):1555-1565

*Department of Gastroenterology, Guy's and St Thomas' Hospital NHS Foundation Trust, London, United Kingdom; and †Western Sydney University, Blacktown Clinical School, Blacktown, Australia.

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http://dx.doi.org/10.1097/MIB.0000000000001183DOI Listing
September 2017

Thioguanine in inflammatory bowel disease: Long-term efficacy and safety.

United European Gastroenterol J 2017 Jun 1;5(4):563-570. Epub 2016 Aug 1.

Department of Gastroenterology, Guy's and St. Thomas' Hospital, NHS Foundation Trust, London, UK.

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http://dx.doi.org/10.1177/2050640616663438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446138PMC
June 2017

Patient optimization for surgery relating to Crohn's disease.

Nat Rev Gastroenterol Hepatol 2016 Dec 26;13(12):707-719. Epub 2016 Oct 26.

IBD Centre, Department of Gastroenterology, First Floor College House, St Thomas' Hospital, Westminster Bridge Road, London, SE1 7EH, UK.

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http://dx.doi.org/10.1038/nrgastro.2016.158DOI Listing
December 2016

Light and Electron Microscopy Methods for Examination of Cochlear Morphology in Mouse Models of Deafness.

Curr Protoc Mouse Biol 2016 Sep 1;6(3):272-306. Epub 2016 Sep 1.

Mammalian Genetics Unit, MRC Harwell, Oxfordshire, United Kingdom.

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http://dx.doi.org/10.1002/cpmo.10DOI Listing
September 2016

Genetic Association Analysis Reveals Differences in the Contribution of NOD2 Variants to the Clinical Phenotypes of Orofacial Granulomatosis.

Inflamm Bowel Dis 2016 07;22(7):1552-8

*Department of Gastroenterology, Guy's and St. Thomas' NHS Foundation Trust and King's College London, London, United Kingdom; †Department of Medical and Molecular Genetics, Faculty of Life Science and Medicine, King's College London, Guy's Hospital, London, United Kingdom; ‡Oral Medicine, Guy's and St. Thomas' NHS Foundation Trust and King's College London, London, United Kingdom; §Diabetes and Nutritional Sciences Division, King's College London, London, United Kingdom; ‖Faculty of Health and Environmental Sciences, AUT University, Auckland, New Zealand; ¶Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom; and **Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of Witwatersrand, South Africa.

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http://dx.doi.org/10.1097/MIB.0000000000000844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912233PMC
July 2016

Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease.

Gut 2016 Apr 24;65(4):584-94. Epub 2015 Feb 24.

Medical Research Council Centre for Transplantation, King's College London, London, UK Department of Experimental Immunobiology, King's College London, London, UK National Institute for Health Research Biomedical Research Centre at Guy's and St. Thomas' NHS Foundation Trust and King's College London, London, UK.

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http://dx.doi.org/10.1136/gutjnl-2014-306919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819603PMC
April 2016

Prevalence and Risk Factors for Functional Vitamin B12 Deficiency in Patients with Crohn's Disease.

Inflamm Bowel Dis 2015 Dec;21(12):2839-47

*Department of Gastroenterology, Guy's and St Thomas' Hospital NHS Foundation Trust, London, United Kingdom; †The Nutristasis Unit, Viapath, St Thomas' Hospital, London, United Kingdom; ‡Department of Radiology, Guy's and St Thomas' Hospital NHS Foundation Trust, London, United Kingdom; and §Diabetes and Nutritional Sciences Division, School of Medicine, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1097/MIB.0000000000000559DOI Listing
December 2015

Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data.

Lancet Oncol 2015 Dec 23;16(16):1639-50. Epub 2015 Oct 23.

Department of Clinical Pharmacology, Netherlands Cancer Institute, Amsterdam, Netherlands; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, Netherlands; Division of Pharmacoepidemiology and Clinical Pharmacology, Department of Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, Netherlands. Electronic address:

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http://www.thelancet.com/pdfs/journals/lanonc/PIIS1470-2045(
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http://linkinghub.elsevier.com/retrieve/pii/S147020451500286
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http://dx.doi.org/10.1016/S1470-2045(15)00286-7DOI Listing
December 2015

TPMT Testing Before Starting Azathioprine or Mercaptopurine: Surely Just Do It?

Gastroenterology 2015 Oct 24;149(4):850-3. Epub 2015 Aug 24.

Department of Gastroenterology, Guy's & St. Thomas' Hospitals NHS Foundation Trust, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2015.08.040DOI Listing
October 2015

Getting the best out of thiopurine therapy: thiopurine S-methyltransferase and beyond.

Biomark Med 2015 ;9(1):51-65

Department of Gastroenterology, St Thomas Hospital, Westminster Bridge Road, London, UK.

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http://dx.doi.org/10.2217/bmm.14.97DOI Listing
September 2015

Interleukin 6 Increases Production of Cytokines by Colonic Innate Lymphoid Cells in Mice and Patients With Chronic Intestinal Inflammation.

Gastroenterology 2015 Aug 25;149(2):456-67.e15. Epub 2015 Apr 25.

Department of Experimental Immunobiology, Division of Transplantation Immunology and Mucosal Biology, King's College London, London, United Kingdom; National Institute for Health Research Biomedical Research Centre, Guy's and St Thomas' National Health Service Foundation Trust, London, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085150057
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http://dx.doi.org/10.1053/j.gastro.2015.04.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539618PMC
August 2015

A guide to oral ulceration for the medical physician.

Br J Hosp Med (Lond) 2015 Jun;76(6):337-42

Reader in Oral Medicine at King's College London Dental Institute and Honorary Consultant in Oral Medicine in the Oral Medicine Unit, Guy's, King's & St Thomas' Hospitals, London SE1 7EH.

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http://dx.doi.org/10.12968/hmed.2015.76.6.337DOI Listing
June 2015

Optimizing the use of thiopurines in inflammatory bowel disease.

Ther Adv Chronic Dis 2015 May;6(3):138-46

Guy's & St Thomas' Hospitals - Gastroenterology, London, UK.

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http://dx.doi.org/10.1177/2040622315579063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416969PMC
May 2015

Characterization of virus-like particles associated with the human faecal and caecal microbiota.

Res Microbiol 2014 Dec 22;165(10):803-12. Epub 2014 Oct 22.

School of Microbiology, University College Cork, Western Road, Cork, Ireland; Alimentary Pharmabiotic Centre, Biosciences Institute, National University of Ireland, Western Road, Cork, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.resmic.2014.10.006DOI Listing
December 2014

Hidradenitis suppurativa: MRI features in anogenital disease.

Dis Colon Rectum 2014 Jun;57(6):762-71

1Department of Radiology, Guy's and St Thomas' National Health Service Foundation Trust, London, United Kingdom 2Department of General Surgery, Guy's and St Thomas' National Health Service Foundation Trust, London, United Kingdom 3Department of Gastroenterology, Guy's and St Thomas' National Health Service Foundation Trust, London, United Kingdom 4Department of Dermatology, Guy's and St Thomas' National Health Service Foundation Trust, London, United Kingdom 5Division of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1097/DCR.0000000000000131DOI Listing
June 2014

Reply to Dr. Marques do Santos' letter - should we treat asymptomatic patients with mildly ulcerated terminal ileum?

J Crohns Colitis 2014 May 4;8(5):438. Epub 2013 Dec 4.

Department of Gastroenterology, Guy's and St Thomas' NHS Foundation Trust, London, UK.

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http://dx.doi.org/10.1016/j.crohns.2013.11.012DOI Listing
May 2014

Oesophageal Crohn's disease: a novel approach to managing iatrogenic perforation of an oesophageal Crohn's stricture.

J Crohns Colitis 2014 Apr 20;8(4):332-3. Epub 2013 Nov 20.

Guy's and St Thomas' NHS Foundation Trust, London, UK.

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http://ecco-jcc.oxfordjournals.org/content/eccojc/8/4/332.fu
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http://dx.doi.org/10.1016/j.crohns.2013.11.002DOI Listing
April 2014

Alopecia areata: a possible extraintestinal manifestation of Crohn's disease.

J Crohns Colitis 2013 Nov 3;7(10):e503. Epub 2013 Jun 3.

Department of Gastroenterology, Guy's and St Thomas' NHS Foundation Trust, London, UK.

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http://dx.doi.org/10.1016/j.crohns.2013.05.004DOI Listing
November 2013

Quantification and characterization of mucosa-associated and intracellular Escherichia coli in inflammatory bowel disease.

Inflamm Bowel Dis 2013 Oct;19(11):2326-38

*Diabetes and Nutritional Sciences Division, King's College London, London, United Kingdom; †Department of Gastroenterology, Guy's and St. Thomas' NHS Foundation Trust, St Thomas' Hospital, London, United Kingdom; ‡Department of Medicine, University of Melbourne, Melbourne, Australia; §Animal Health and Veterinary Laboratories Agency, Surrey, United Kingdom; and ‖US Department of Agriculture, Agricultural Research Service, Western Regional Research Center, Produce Safety and Microbiology Research Unit, Albany, California.

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http://pdfs.journals.lww.com/ibdjournal/2013/10000/Quantific
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MIB.0b013e3182a38a92DOI Listing
October 2013

Rehabilitation of a parotidectomy patient--a systematic approach.

Head Neck 2013 Sep 21;35(9):1349-61. Epub 2012 Aug 21.

Department of Otolaryngology, Division of Head and Neck Surgery, University of Nebraska Medical Center and Nebraska Methodist Hospital, Omaha, Nebraska, USA.

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http://dx.doi.org/10.1002/hed.23095DOI Listing
September 2013

A role for gut-associated lymphoid tissue in shaping the human B cell repertoire.

J Exp Med 2013 Aug 12;210(9):1665-74. Epub 2013 Aug 12.

Blizard Institute and 2 Digestive Diseases Clinical Academic Unit, Barts and the London School of Medicine and Dentistry, Whitechapel, London, England, UK.

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http://dx.doi.org/10.1084/jem.20122465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754866PMC
August 2013

Hair loss in patients with inflammatory bowel disease.

Inflamm Bowel Dis 2013 Jul;19(8):1753-63

Department of Gastroenterology, Guy's and St Thomas' Hospital, London, United Kingdom.

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http://dx.doi.org/10.1097/MIB.0b013e31828132deDOI Listing
July 2013

Let's get personal: predicting thiopurine and fluoropyrimidine toxicity.

Per Med 2012 Nov;9(8):859-870

Purine Research Laboratory, GSTS Pathology, Guy's & St Thomas' Hospital, Westminster Bridge Road, London SE1 7EH, UK.

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http://dx.doi.org/10.2217/pme.12.91DOI Listing
November 2012

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

Authors:
Luke Jostins Stephan Ripke Rinse K Weersma Richard H Duerr Dermot P McGovern Ken Y Hui James C Lee L Philip Schumm Yashoda Sharma Carl A Anderson Jonah Essers Mitja Mitrovic Kaida Ning Isabelle Cleynen Emilie Theatre Sarah L Spain Soumya Raychaudhuri Philippe Goyette Zhi Wei Clara Abraham Jean-Paul Achkar Tariq Ahmad Leila Amininejad Ashwin N Ananthakrishnan Vibeke Andersen Jane M Andrews Leonard Baidoo Tobias Balschun Peter A Bampton Alain Bitton Gabrielle Boucher Stephan Brand Carsten Büning Ariella Cohain Sven Cichon Mauro D'Amato Dirk De Jong Kathy L Devaney Marla Dubinsky Cathryn Edwards David Ellinghaus Lynnette R Ferguson Denis Franchimont Karin Fransen Richard Gearry Michel Georges Christian Gieger Jürgen Glas Talin Haritunians Ailsa Hart Chris Hawkey Matija Hedl Xinli Hu Tom H Karlsen Limas Kupcinskas Subra Kugathasan Anna Latiano Debby Laukens Ian C Lawrance Charlie W Lees Edouard Louis Gillian Mahy John Mansfield Angharad R Morgan Craig Mowat William Newman Orazio Palmieri Cyriel Y Ponsioen Uros Potocnik Natalie J Prescott Miguel Regueiro Jerome I Rotter Richard K Russell Jeremy D Sanderson Miquel Sans Jack Satsangi Stefan Schreiber Lisa A Simms Jurgita Sventoraityte Stephan R Targan Kent D Taylor Mark Tremelling Hein W Verspaget Martine De Vos Cisca Wijmenga David C Wilson Juliane Winkelmann Ramnik J Xavier Sebastian Zeissig Bin Zhang Clarence K Zhang Hongyu Zhao Mark S Silverberg Vito Annese Hakon Hakonarson Steven R Brant Graham Radford-Smith Christopher G Mathew John D Rioux Eric E Schadt Mark J Daly Andre Franke Miles Parkes Severine Vermeire Jeffrey C Barrett Judy H Cho

Nature 2012 Nov;491(7422):119-24

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK.

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http://dx.doi.org/10.1038/nature11582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491803PMC
November 2012

Optimising outcome on thiopurines in inflammatory bowel disease by co-prescription of allopurinol.

J Crohns Colitis 2012 Oct 3;6(9):905-12. Epub 2012 Mar 3.

Department of Gastroenterology, Guy's & St. Thomas' NHS Foundation Trust, London, UK.

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http://dx.doi.org/10.1016/j.crohns.2012.02.007DOI Listing
October 2012

Anti-infliximab antibodies in inflammatory bowel disease: prevalence, infusion reactions, immunosuppression and response, a meta-analysis.

Eur J Gastroenterol Hepatol 2012 Sep;24(9):1078-85

Department of Gastroenterology, Guy's and St Thomas' NHS Foundation Trust, London, UK.

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https://insights.ovid.com/crossref?an=00042737-201209000-000
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http://dx.doi.org/10.1097/MEG.0b013e32835558cfDOI Listing
September 2012

The pharmacogenetic basis of individual variation in thiopurine metabolism.

Per Med 2012 Sep;9(7):707-725

Department of Gastroenterology, 1st Floor College House, St Thomas' Hospital, Westminster Bridge Road, London, SE1 7EH, London, UK.

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http://dx.doi.org/10.2217/pme.12.85DOI Listing
September 2012

Small bowel MR enterography: problem solving in Crohn's disease.

Insights Imaging 2012 Jun 17;3(3):251-63. Epub 2012 Mar 17.

Department of Radiology, Guy's & St Thomas' Hospital, Westminster Bridge Road, London, SE1 7EH, UK,

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http://dx.doi.org/10.1007/s13244-012-0154-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369125PMC
June 2012

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

Authors:
Carl A Anderson Gabrielle Boucher Charlie W Lees Andre Franke Mauro D'Amato Kent D Taylor James C Lee Philippe Goyette Marcin Imielinski Anna Latiano Caroline Lagacé Regan Scott Leila Amininejad Suzannah Bumpstead Leonard Baidoo Robert N Baldassano Murray Barclay Theodore M Bayless Stephan Brand Carsten Büning Jean-Frédéric Colombel Lee A Denson Martine De Vos Marla Dubinsky Cathryn Edwards David Ellinghaus Rudolf S N Fehrmann James A B Floyd Timothy Florin Denis Franchimont Lude Franke Michel Georges Jürgen Glas Nicole L Glazer Stephen L Guthery Talin Haritunians Nicholas K Hayward Jean-Pierre Hugot Gilles Jobin Debby Laukens Ian Lawrance Marc Lémann Arie Levine Cecile Libioulle Edouard Louis Dermot P McGovern Monica Milla Grant W Montgomery Katherine I Morley Craig Mowat Aylwin Ng William Newman Roel A Ophoff Laura Papi Orazio Palmieri Laurent Peyrin-Biroulet Julián Panés Anne Phillips Natalie J Prescott Deborah D Proctor Rebecca Roberts Richard Russell Paul Rutgeerts Jeremy Sanderson Miquel Sans Philip Schumm Frank Seibold Yashoda Sharma Lisa A Simms Mark Seielstad A Hillary Steinhart Stephan R Targan Leonard H van den Berg Morten Vatn Hein Verspaget Thomas Walters Cisca Wijmenga David C Wilson Harm-Jan Westra Ramnik J Xavier Zhen Z Zhao Cyriel Y Ponsioen Vibeke Andersen Leif Torkvist Maria Gazouli Nicholas P Anagnou Tom H Karlsen Limas Kupcinskas Jurgita Sventoraityte John C Mansfield Subra Kugathasan Mark S Silverberg Jonas Halfvarson Jerome I Rotter Christopher G Mathew Anne M Griffiths Richard Gearry Tariq Ahmad Steven R Brant Mathias Chamaillard Jack Satsangi Judy H Cho Stefan Schreiber Mark J Daly Jeffrey C Barrett Miles Parkes Vito Annese Hakon Hakonarson Graham Radford-Smith Richard H Duerr Séverine Vermeire Rinse K Weersma John D Rioux

Nat Genet 2011 Mar 6;43(3):246-52. Epub 2011 Feb 6.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084597PMC
March 2011

Experience with anti-TNF-α therapy for orofacial granulomatosis.

J Oral Pathol Med 2011 Jan;40(1):14-9

Department of Gastroenterology, Guy's and St. Thomas' NHS Foundation Trust and King's College London, London, UK.

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http://dx.doi.org/10.1111/j.1600-0714.2010.00976.xDOI Listing
January 2011

Colocalization analysis in fluorescence micrographs: verification of a more accurate calculation of pearson's correlation coefficient.

Microsc Microanal 2010 Dec 15;16(6):710-24. Epub 2010 Oct 15.

PerkinElmer, Viscount Centre II, Millburn Hill Road, Warwick University Science Park, Coventry CV4 7HS, UK.

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http://dx.doi.org/10.1017/S143192761009389XDOI Listing
December 2010

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.

Nat Genet 2010 Dec;42(12):1118-25

Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel, Kiel, Germany.

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http://dx.doi.org/10.1038/ng.717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299551PMC
December 2010

Subepithelial dendritic B cells in orofacial granulomatosis.

Inflamm Bowel Dis 2010 Jun;16(6):1051-60

Department of Gastroenterology at Guy's & St. Thomas NHS Foundation Trust, London, UK.

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http://dx.doi.org/10.1002/ibd.21169DOI Listing
June 2010

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls.

Authors:
Nick Craddock Matthew E Hurles Niall Cardin Richard D Pearson Vincent Plagnol Samuel Robson Damjan Vukcevic Chris Barnes Donald F Conrad Eleni Giannoulatou Chris Holmes Jonathan L Marchini Kathy Stirrups Martin D Tobin Louise V Wain Chris Yau Jan Aerts Tariq Ahmad T Daniel Andrews Hazel Arbury Anthony Attwood Adam Auton Stephen G Ball Anthony J Balmforth Jeffrey C Barrett Inês Barroso Anne Barton Amanda J Bennett Sanjeev Bhaskar Katarzyna Blaszczyk John Bowes Oliver J Brand Peter S Braund Francesca Bredin Gerome Breen Morris J Brown Ian N Bruce Jaswinder Bull Oliver S Burren John Burton Jake Byrnes Sian Caesar Chris M Clee Alison J Coffey John M C Connell Jason D Cooper Anna F Dominiczak Kate Downes Hazel E Drummond Darshna Dudakia Andrew Dunham Bernadette Ebbs Diana Eccles Sarah Edkins Cathryn Edwards Anna Elliot Paul Emery David M Evans Gareth Evans Steve Eyre Anne Farmer I Nicol Ferrier Lars Feuk Tomas Fitzgerald Edward Flynn Alistair Forbes Liz Forty Jayne A Franklyn Rachel M Freathy Polly Gibbs Paul Gilbert Omer Gokumen Katherine Gordon-Smith Emma Gray Elaine Green Chris J Groves Detelina Grozeva Rhian Gwilliam Anita Hall Naomi Hammond Matt Hardy Pile Harrison Neelam Hassanali Husam Hebaishi Sarah Hines Anne Hinks Graham A Hitman Lynne Hocking Eleanor Howard Philip Howard Joanna M M Howson Debbie Hughes Sarah Hunt John D Isaacs Mahim Jain Derek P Jewell Toby Johnson Jennifer D Jolley Ian R Jones Lisa A Jones George Kirov Cordelia F Langford Hana Lango-Allen G Mark Lathrop James Lee Kate L Lee Charlie Lees Kevin Lewis Cecilia M Lindgren Meeta Maisuria-Armer Julian Maller John Mansfield Paul Martin Dunecan C O Massey Wendy L McArdle Peter McGuffin Kirsten E McLay Alex Mentzer Michael L Mimmack Ann E Morgan Andrew P Morris Craig Mowat Simon Myers William Newman Elaine R Nimmo Michael C O'Donovan Abiodun Onipinla Ifejinelo Onyiah Nigel R Ovington Michael J Owen Kimmo Palin Kirstie Parnell David Pernet John R B Perry Anne Phillips Dalila Pinto Natalie J Prescott Inga Prokopenko Michael A Quail Suzanne Rafelt Nigel W Rayner Richard Redon David M Reid Renwick Susan M Ring Neil Robertson Ellie Russell David St Clair Jennifer G Sambrook Jeremy D Sanderson Helen Schuilenburg Carol E Scott Richard Scott Sheila Seal Sue Shaw-Hawkins Beverley M Shields Matthew J Simmonds Debbie J Smyth Elilan Somaskantharajah Katarina Spanova Sophia Steer Jonathan Stephens Helen E Stevens Millicent A Stone Zhan Su Deborah P M Symmons John R Thompson Wendy Thomson Mary E Travers Clare Turnbull Armand Valsesia Mark Walker Neil M Walker Chris Wallace Margaret Warren-Perry Nicholas A Watkins John Webster Michael N Weedon Anthony G Wilson Matthew Woodburn B Paul Wordsworth Allan H Young Eleftheria Zeggini Nigel P Carter Timothy M Frayling Charles Lee Gil McVean Patricia B Munroe Aarno Palotie Stephen J Sawcer Stephen W Scherer David P Strachan Chris Tyler-Smith Matthew A Brown Paul R Burton Mark J Caulfield Alastair Compston Martin Farrall Stephen C L Gough Alistair S Hall Andrew T Hattersley Adrian V S Hill Christopher G Mathew Marcus Pembrey Jack Satsangi Michael R Stratton Jane Worthington Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem Ouwehand Miles Parkes Nazneen Rahman John A Todd Nilesh J Samani Peter Donnelly

Nature 2010 Apr;464(7289):713-20

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http://dx.doi.org/10.1038/nature08979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892339PMC
April 2010

Pharmacogenomics in the treatment of inflammatory bowel disease.

Pharmacogenomics 2010 Mar;11(3):421-37

Department of Gastroenterology, 1st Floor, College House, St Thomas' Hospital, Lambeth Palace Road, London, SE1 7EH, UK.

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http://dx.doi.org/10.2217/pgs.10.4DOI Listing
March 2010

The contribution of deleterious DPYD gene sequence variants to fluoropyrimidine toxicity in British cancer patients.

Cancer Chemother Pharmacol 2010 Jan 1;65(2):403-6. Epub 2009 Oct 1.

Department of Gastroenterology, Guy's and St Thomas' Hospital NHS Foundation Trust, College House, St Thomas' Hospital, London, UK.

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http://dx.doi.org/10.1007/s00280-009-1147-xDOI Listing
January 2010

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.

Nat Genet 2009 Dec 15;41(12):1330-4. Epub 2009 Nov 15.

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http://dx.doi.org/10.1038/ng.483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812019PMC
December 2009

The mechanisms and efficacy of probiotics in the prevention of Clostridium difficile-associated diarrhoea.

Lancet Infect Dis 2009 Apr;9(4):237-44

Nutritional Sciences Division, King's College London, London, UK.

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http://dx.doi.org/10.1016/S1473-3099(09)70059-3DOI Listing
April 2009

Further experience with the use of 6-thioguanine in patients with Crohn's disease.

Inflamm Bowel Dis 2008 Oct;14(10):1399-405

Department of Gastroenterology, Guy's & St. Thomas' Hospitals NHS Foundation Trust, London SE1 7EH, United Kingdom.

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http://dx.doi.org/10.1002/ibd.20492DOI Listing
October 2008

Gastrointestinal microbiota in irritable bowel syndrome: their role in its pathogenesis and treatment.

Am J Gastroenterol 2008 Jun 29;103(6):1557-67. Epub 2008 May 29.

Diet and Gastrointestinal Health, Nutritional Sciences Division, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1111/j.1572-0241.2008.01869.xDOI Listing
June 2008

Mycobacterium avium subspecies paratuberculosis infection in cases of irritable bowel syndrome and comparison with Crohn's disease and Johne's disease: common neural and immune pathogenicities.

J Clin Microbiol 2007 Dec 3;45(12):3883-90. Epub 2007 Oct 3.

Instituto di Clinica Chirurgica Generale, Sezione di Microbiologia Sperimentale e Clinica, Universita degli Studi di Sassari, Sassari, Italy.

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http://dx.doi.org/10.1128/JCM.01371-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2168579PMC
December 2007

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.

Authors:
Paul R Burton David G Clayton Lon R Cardon Nick Craddock Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem H Ouwehand Nilesh J Samani John A Todd Peter Donnelly Jeffrey C Barrett Dan Davison Doug Easton David M Evans Hin-Tak Leung Jonathan L Marchini Andrew P Morris Chris C A Spencer Martin D Tobin Antony P Attwood James P Boorman Barbara Cant Ursula Everson Judith M Hussey Jennifer D Jolley Alexandra S Knight Kerstin Koch Elizabeth Meech Sarah Nutland Christopher V Prowse Helen E Stevens Niall C Taylor Graham R Walters Neil M Walker Nicholas A Watkins Thilo Winzer Richard W Jones Wendy L McArdle Susan M Ring David P Strachan Marcus Pembrey Gerome Breen David St Clair Sian Caesar Katharine Gordon-Smith Lisa Jones Christine Fraser Elaine K Green Detelina Grozeva Marian L Hamshere Peter A Holmans Ian R Jones George Kirov Valentina Moskivina Ivan Nikolov Michael C O'Donovan Michael J Owen David A Collier Amanda Elkin Anne Farmer Richard Williamson Peter McGuffin Allan H Young I Nicol Ferrier Stephen G Ball Anthony J Balmforth Jennifer H Barrett Timothy D Bishop Mark M Iles Azhar Maqbool Nadira Yuldasheva Alistair S Hall Peter S Braund Richard J Dixon Massimo Mangino Suzanne Stevens John R Thompson Francesca Bredin Mark Tremelling Miles Parkes Hazel Drummond Charles W Lees Elaine R Nimmo Jack Satsangi Sheila A Fisher Alastair Forbes Cathryn M Lewis Clive M Onnie Natalie J Prescott Jeremy Sanderson Christopher G Matthew Jamie Barbour M Khalid Mohiuddin Catherine E Todhunter John C Mansfield Tariq Ahmad Fraser R Cummings Derek P Jewell John Webster Morris J Brown Mark G Lathrop John Connell Anna Dominiczak Carolina A Braga Marcano Beverley Burke Richard Dobson Johannie Gungadoo Kate L Lee Patricia B Munroe Stephen J Newhouse Abiodun Onipinla Chris Wallace Mingzhan Xue Mark Caulfield Martin Farrall Anne Barton Ian N Bruce Hannah Donovan Steve Eyre Paul D Gilbert Samantha L Hilder Anne M Hinks Sally L John Catherine Potter Alan J Silman Deborah P M Symmons Wendy Thomson Jane Worthington David B Dunger Barry Widmer Timothy M Frayling Rachel M Freathy Hana Lango John R B Perry Beverley M Shields Michael N Weedon Andrew T Hattersley Graham A Hitman Mark Walker Kate S Elliott Christopher J Groves Cecilia M Lindgren Nigel W Rayner Nicolas J Timpson Eleftheria Zeggini Melanie Newport Giorgio Sirugo Emily Lyons Fredrik Vannberg Adrian V S Hill Linda A Bradbury Claire Farrar Jennifer J Pointon Paul Wordsworth Matthew A Brown Jayne A Franklyn Joanne M Heward Matthew J Simmonds Stephen C L Gough Sheila Seal Michael R Stratton Nazneen Rahman Maria Ban An Goris Stephen J Sawcer Alastair Compston David Conway Muminatou Jallow Melanie Newport Giorgio Sirugo Kirk A Rockett Suzannah J Bumpstead Amy Chaney Kate Downes Mohammed J R Ghori Rhian Gwilliam Sarah E Hunt Michael Inouye Andrew Keniry Emma King Ralph McGinnis Simon Potter Rathi Ravindrarajah Pamela Whittaker Claire Widden David Withers Niall J Cardin Dan Davison Teresa Ferreira Joanne Pereira-Gale Ingeleif B Hallgrimsdo'ttir Bryan N Howie Zhan Su Yik Ying Teo Damjan Vukcevic David Bentley Matthew A Brown Alastair Compston Martin Farrall Alistair S Hall Andrew T Hattersley Adrian V S Hill Miles Parkes Marcus Pembrey Michael R Stratton Sarah L Mitchell Paul R Newby Oliver J Brand Jackie Carr-Smith Simon H S Pearce R McGinnis A Keniry P Deloukas John D Reveille Xiaodong Zhou Anne-Marie Sims Alison Dowling Jacqueline Taylor Tracy Doan John C Davis Laurie Savage Michael M Ward Thomas L Learch Michael H Weisman Mathew Brown

Nat Genet 2007 Nov 21;39(11):1329-37. Epub 2007 Oct 21.

Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Adrian Building, University Road, Leicester LE1 7RH, UK.

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http://dx.doi.org/10.1038/ng.2007.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680141PMC
November 2007

A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5.

Gastroenterology 2007 May 24;132(5):1665-71. Epub 2007 Mar 24.

Department of Medical and Molecular Genetics, King's College London School of Medicine, Guy's Hospital, London, UK.

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http://dx.doi.org/10.1053/j.gastro.2007.03.034DOI Listing
May 2007

The ITPA c.94C>A and g.IVS2+21A>C sequence variants contribute to missplicing of the ITPA gene.

Biochim Biophys Acta 2007 Jan 18;1772(1):96-102. Epub 2006 Oct 18.

Purine Research Laboratory, Department of Chemical Pathology, Guy's Hospital, London, SE1 9RT, UK, and Department of Paediatrics, Neonatology and Congenital Disorders, Nagoya City University, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S092544390600198
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http://dx.doi.org/10.1016/j.bbadis.2006.10.006DOI Listing
January 2007

A new configuration of the Zeiss LSM 510 for simultaneous optical separation of green and red fluorescent protein pairs.

Cytometry A 2006 Aug;69(8):920-9

Beatson Institute for Cancer Research, Glasgow, UK.

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http://dx.doi.org/10.1002/cyto.a.20323DOI Listing
August 2006