Publications by authors named "Jeremy Sanderson"

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Clin Gastroenterol Hepatol 2020 Jul 21. Epub 2020 Jul 21.

Department of Gastroenterology, Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom.

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July 2020

Pyoderma gangrenosum of the tongue.

Br J Hosp Med (Lond) 2020 Jun;81(6):1-4

Department of Oral Medicine, Dental Institute, Guy's and St Thomas' NHS Foundation Trust, London, UK.

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June 2020

Fundamentals of Microscopy.

Authors:
Jeremy Sanderson

Curr Protoc Mouse Biol 2020 Jun;10(2):e76

Bioimaging Facility Manager, MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Oxfordshire, UK.

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June 2020

Streptococcus Salivarius: A Potential Salivary Biomarker for Orofacial Granulomatosis and Crohn's Disease?

Inflamm Bowel Dis 2019 07;25(8):1367-1374

Department of Medical and Molecular Genetics, Faculty of Life Science and Medicine, King's College London, London, United Kingdom.

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July 2019

Correction of Defective T-Regulatory Cells From Patients With Crohn's Disease by Ex Vivo Ligation of Retinoic Acid Receptor-α.

Gastroenterology 2019 05 30;156(6):1775-1787. Epub 2019 Jan 30.

School of Immunology and Microbial Sciences, King's College London, London, UK; National Institute for Health Research Biomedical Research Centre, Guy's and St Thomas' NHS Trust and King's College London, London, UK. Electronic address:

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May 2019

Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota.

Microbiome 2018 04 20;6(1):73. Epub 2018 Apr 20.

Integrative Systems Medicine and Digestive Disease, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Exhibition Road, London, SW7 2AZ, UK.

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April 2018

A practical guide to thiopurine prescribing and monitoring in IBD.

Frontline Gastroenterol 2018 Jan 29;9(1):10-15. Epub 2016 Aug 29.

Department of Gastroenterology, Guy's and St Thomas' NHS Foundation Trust, London, UK.

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January 2018

A Case of Unusual Ileal Discoloration.

Gastroenterology 2018 07 6;155(1):e1-e2. Epub 2017 Oct 6.

Gastroenterology, Guy's and St Thomas' NHS Foundation Trust, London, UK.

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July 2018

Thioguanine in inflammatory bowel disease: Long-term efficacy and safety.

United European Gastroenterol J 2017 Jun 1;5(4):563-570. Epub 2016 Aug 1.

Department of Gastroenterology, Guy's and St. Thomas' Hospital, NHS Foundation Trust, London, UK.

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June 2017

Patient optimization for surgery relating to Crohn's disease.

Nat Rev Gastroenterol Hepatol 2016 Dec 26;13(12):707-719. Epub 2016 Oct 26.

IBD Centre, Department of Gastroenterology, First Floor College House, St Thomas' Hospital, Westminster Bridge Road, London, SE1 7EH, UK.

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December 2016

Light and Electron Microscopy Methods for Examination of Cochlear Morphology in Mouse Models of Deafness.

Curr Protoc Mouse Biol 2016 Sep 1;6(3):272-306. Epub 2016 Sep 1.

Mammalian Genetics Unit, MRC Harwell, Oxfordshire, United Kingdom.

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September 2016

Genetic Association Analysis Reveals Differences in the Contribution of NOD2 Variants to the Clinical Phenotypes of Orofacial Granulomatosis.

Inflamm Bowel Dis 2016 07;22(7):1552-8

*Department of Gastroenterology, Guy's and St. Thomas' NHS Foundation Trust and King's College London, London, United Kingdom; †Department of Medical and Molecular Genetics, Faculty of Life Science and Medicine, King's College London, Guy's Hospital, London, United Kingdom; ‡Oral Medicine, Guy's and St. Thomas' NHS Foundation Trust and King's College London, London, United Kingdom; §Diabetes and Nutritional Sciences Division, King's College London, London, United Kingdom; ‖Faculty of Health and Environmental Sciences, AUT University, Auckland, New Zealand; ¶Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom; and **Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of Witwatersrand, South Africa.

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July 2016

Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data.

Lancet Oncol 2015 Dec 23;16(16):1639-50. Epub 2015 Oct 23.

Department of Clinical Pharmacology, Netherlands Cancer Institute, Amsterdam, Netherlands; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, Netherlands; Division of Pharmacoepidemiology and Clinical Pharmacology, Department of Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, Netherlands. Electronic address:

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December 2015

TPMT Testing Before Starting Azathioprine or Mercaptopurine: Surely Just Do It?

Gastroenterology 2015 Oct 24;149(4):850-3. Epub 2015 Aug 24.

Department of Gastroenterology, Guy's & St. Thomas' Hospitals NHS Foundation Trust, London, United Kingdom. Electronic address:

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October 2015

Prevalence and Risk Factors for Functional Vitamin B12 Deficiency in Patients with Crohn's Disease.

Inflamm Bowel Dis 2015 Dec;21(12):2839-47

*Department of Gastroenterology, Guy's and St Thomas' Hospital NHS Foundation Trust, London, United Kingdom; †The Nutristasis Unit, Viapath, St Thomas' Hospital, London, United Kingdom; ‡Department of Radiology, Guy's and St Thomas' Hospital NHS Foundation Trust, London, United Kingdom; and §Diabetes and Nutritional Sciences Division, School of Medicine, King's College London, London, United Kingdom.

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December 2015

A guide to oral ulceration for the medical physician.

Br J Hosp Med (Lond) 2015 Jun;76(6):337-42

Reader in Oral Medicine at King's College London Dental Institute and Honorary Consultant in Oral Medicine in the Oral Medicine Unit, Guy's, King's & St Thomas' Hospitals, London SE1 7EH.

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June 2015

Optimizing the use of thiopurines in inflammatory bowel disease.

Ther Adv Chronic Dis 2015 May;6(3):138-46

Guy's & St Thomas' Hospitals - Gastroenterology, London, UK.

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May 2015

Interleukin 6 Increases Production of Cytokines by Colonic Innate Lymphoid Cells in Mice and Patients With Chronic Intestinal Inflammation.

Gastroenterology 2015 Aug 25;149(2):456-67.e15. Epub 2015 Apr 25.

Department of Experimental Immunobiology, Division of Transplantation Immunology and Mucosal Biology, King's College London, London, United Kingdom; National Institute for Health Research Biomedical Research Centre, Guy's and St Thomas' National Health Service Foundation Trust, London, United Kingdom. Electronic address:

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August 2015

Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease.

Gut 2016 Apr 24;65(4):584-94. Epub 2015 Feb 24.

Medical Research Council Centre for Transplantation, King's College London, London, UK Department of Experimental Immunobiology, King's College London, London, UK National Institute for Health Research Biomedical Research Centre at Guy's and St. Thomas' NHS Foundation Trust and King's College London, London, UK.

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April 2016

Characterization of virus-like particles associated with the human faecal and caecal microbiota.

Res Microbiol 2014 Dec 22;165(10):803-12. Epub 2014 Oct 22.

School of Microbiology, University College Cork, Western Road, Cork, Ireland; Alimentary Pharmabiotic Centre, Biosciences Institute, National University of Ireland, Western Road, Cork, Ireland. Electronic address:

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December 2014

Hidradenitis suppurativa: MRI features in anogenital disease.

Dis Colon Rectum 2014 Jun;57(6):762-71

1Department of Radiology, Guy's and St Thomas' National Health Service Foundation Trust, London, United Kingdom 2Department of General Surgery, Guy's and St Thomas' National Health Service Foundation Trust, London, United Kingdom 3Department of Gastroenterology, Guy's and St Thomas' National Health Service Foundation Trust, London, United Kingdom 4Department of Dermatology, Guy's and St Thomas' National Health Service Foundation Trust, London, United Kingdom 5Division of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom.

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June 2014

Reply to Dr. Marques do Santos' letter - should we treat asymptomatic patients with mildly ulcerated terminal ileum?

J Crohns Colitis 2014 May 4;8(5):438. Epub 2013 Dec 4.

Department of Gastroenterology, Guy's and St Thomas' NHS Foundation Trust, London, UK.

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May 2014

Oesophageal Crohn's disease: a novel approach to managing iatrogenic perforation of an oesophageal Crohn's stricture.

J Crohns Colitis 2014 Apr 20;8(4):332-3. Epub 2013 Nov 20.

Guy's and St Thomas' NHS Foundation Trust, London, UK.

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April 2014

Quantification and characterization of mucosa-associated and intracellular Escherichia coli in inflammatory bowel disease.

Inflamm Bowel Dis 2013 Oct;19(11):2326-38

*Diabetes and Nutritional Sciences Division, King's College London, London, United Kingdom; †Department of Gastroenterology, Guy's and St. Thomas' NHS Foundation Trust, St Thomas' Hospital, London, United Kingdom; ‡Department of Medicine, University of Melbourne, Melbourne, Australia; §Animal Health and Veterinary Laboratories Agency, Surrey, United Kingdom; and ‖US Department of Agriculture, Agricultural Research Service, Western Regional Research Center, Produce Safety and Microbiology Research Unit, Albany, California.

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October 2013

A role for gut-associated lymphoid tissue in shaping the human B cell repertoire.

J Exp Med 2013 Aug 12;210(9):1665-74. Epub 2013 Aug 12.

Blizard Institute and 2 Digestive Diseases Clinical Academic Unit, Barts and the London School of Medicine and Dentistry, Whitechapel, London, England, UK.

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August 2013

Alopecia areata: a possible extraintestinal manifestation of Crohn's disease.

J Crohns Colitis 2013 Nov 3;7(10):e503. Epub 2013 Jun 3.

Department of Gastroenterology, Guy's and St Thomas' NHS Foundation Trust, London, UK.

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November 2013

Hair loss in patients with inflammatory bowel disease.

Inflamm Bowel Dis 2013 Jul;19(8):1753-63

Department of Gastroenterology, Guy's and St Thomas' Hospital, London, United Kingdom.

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July 2013

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

Authors:
Luke Jostins Stephan Ripke Rinse K Weersma Richard H Duerr Dermot P McGovern Ken Y Hui James C Lee L Philip Schumm Yashoda Sharma Carl A Anderson Jonah Essers Mitja Mitrovic Kaida Ning Isabelle Cleynen Emilie Theatre Sarah L Spain Soumya Raychaudhuri Philippe Goyette Zhi Wei Clara Abraham Jean-Paul Achkar Tariq Ahmad Leila Amininejad Ashwin N Ananthakrishnan Vibeke Andersen Jane M Andrews Leonard Baidoo Tobias Balschun Peter A Bampton Alain Bitton Gabrielle Boucher Stephan Brand Carsten Büning Ariella Cohain Sven Cichon Mauro D'Amato Dirk De Jong Kathy L Devaney Marla Dubinsky Cathryn Edwards David Ellinghaus Lynnette R Ferguson Denis Franchimont Karin Fransen Richard Gearry Michel Georges Christian Gieger Jürgen Glas Talin Haritunians Ailsa Hart Chris Hawkey Matija Hedl Xinli Hu Tom H Karlsen Limas Kupcinskas Subra Kugathasan Anna Latiano Debby Laukens Ian C Lawrance Charlie W Lees Edouard Louis Gillian Mahy John Mansfield Angharad R Morgan Craig Mowat William Newman Orazio Palmieri Cyriel Y Ponsioen Uros Potocnik Natalie J Prescott Miguel Regueiro Jerome I Rotter Richard K Russell Jeremy D Sanderson Miquel Sans Jack Satsangi Stefan Schreiber Lisa A Simms Jurgita Sventoraityte Stephan R Targan Kent D Taylor Mark Tremelling Hein W Verspaget Martine De Vos Cisca Wijmenga David C Wilson Juliane Winkelmann Ramnik J Xavier Sebastian Zeissig Bin Zhang Clarence K Zhang Hongyu Zhao Mark S Silverberg Vito Annese Hakon Hakonarson Steven R Brant Graham Radford-Smith Christopher G Mathew John D Rioux Eric E Schadt Mark J Daly Andre Franke Miles Parkes Severine Vermeire Jeffrey C Barrett Judy H Cho

Nature 2012 Nov;491(7422):119-24

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK.

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November 2012

Let's get personal: predicting thiopurine and fluoropyrimidine toxicity.

Per Med 2012 Nov;9(8):859-870

Purine Research Laboratory, GSTS Pathology, Guy's & St Thomas' Hospital, Westminster Bridge Road, London SE1 7EH, UK.

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November 2012

The pharmacogenetic basis of individual variation in thiopurine metabolism.

Per Med 2012 Sep;9(7):707-725

Department of Gastroenterology, 1st Floor College House, St Thomas' Hospital, Westminster Bridge Road, London, SE1 7EH, London, UK.

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September 2012

Rehabilitation of a parotidectomy patient--a systematic approach.

Head Neck 2013 Sep 21;35(9):1349-61. Epub 2012 Aug 21.

Department of Otolaryngology, Division of Head and Neck Surgery, University of Nebraska Medical Center and Nebraska Methodist Hospital, Omaha, Nebraska, USA.

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September 2013

Small bowel MR enterography: problem solving in Crohn's disease.

Insights Imaging 2012 Jun 17;3(3):251-63. Epub 2012 Mar 17.

Department of Radiology, Guy's & St Thomas' Hospital, Westminster Bridge Road, London, SE1 7EH, UK,

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June 2012

Anti-infliximab antibodies in inflammatory bowel disease: prevalence, infusion reactions, immunosuppression and response, a meta-analysis.

Eur J Gastroenterol Hepatol 2012 Sep;24(9):1078-85

Department of Gastroenterology, Guy's and St Thomas' NHS Foundation Trust, London, UK.

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September 2012

Optimising outcome on thiopurines in inflammatory bowel disease by co-prescription of allopurinol.

J Crohns Colitis 2012 Oct 3;6(9):905-12. Epub 2012 Mar 3.

Department of Gastroenterology, Guy's & St. Thomas' NHS Foundation Trust, London, UK.

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October 2012

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

Authors:
Carl A Anderson Gabrielle Boucher Charlie W Lees Andre Franke Mauro D'Amato Kent D Taylor James C Lee Philippe Goyette Marcin Imielinski Anna Latiano Caroline Lagacé Regan Scott Leila Amininejad Suzannah Bumpstead Leonard Baidoo Robert N Baldassano Murray Barclay Theodore M Bayless Stephan Brand Carsten Büning Jean-Frédéric Colombel Lee A Denson Martine De Vos Marla Dubinsky Cathryn Edwards David Ellinghaus Rudolf S N Fehrmann James A B Floyd Timothy Florin Denis Franchimont Lude Franke Michel Georges Jürgen Glas Nicole L Glazer Stephen L Guthery Talin Haritunians Nicholas K Hayward Jean-Pierre Hugot Gilles Jobin Debby Laukens Ian Lawrance Marc Lémann Arie Levine Cecile Libioulle Edouard Louis Dermot P McGovern Monica Milla Grant W Montgomery Katherine I Morley Craig Mowat Aylwin Ng William Newman Roel A Ophoff Laura Papi Orazio Palmieri Laurent Peyrin-Biroulet Julián Panés Anne Phillips Natalie J Prescott Deborah D Proctor Rebecca Roberts Richard Russell Paul Rutgeerts Jeremy Sanderson Miquel Sans Philip Schumm Frank Seibold Yashoda Sharma Lisa A Simms Mark Seielstad A Hillary Steinhart Stephan R Targan Leonard H van den Berg Morten Vatn Hein Verspaget Thomas Walters Cisca Wijmenga David C Wilson Harm-Jan Westra Ramnik J Xavier Zhen Z Zhao Cyriel Y Ponsioen Vibeke Andersen Leif Torkvist Maria Gazouli Nicholas P Anagnou Tom H Karlsen Limas Kupcinskas Jurgita Sventoraityte John C Mansfield Subra Kugathasan Mark S Silverberg Jonas Halfvarson Jerome I Rotter Christopher G Mathew Anne M Griffiths Richard Gearry Tariq Ahmad Steven R Brant Mathias Chamaillard Jack Satsangi Judy H Cho Stefan Schreiber Mark J Daly Jeffrey C Barrett Miles Parkes Vito Annese Hakon Hakonarson Graham Radford-Smith Richard H Duerr Séverine Vermeire Rinse K Weersma John D Rioux

Nat Genet 2011 Mar 6;43(3):246-52. Epub 2011 Feb 6.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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March 2011

Experience with anti-TNF-α therapy for orofacial granulomatosis.

J Oral Pathol Med 2011 Jan;40(1):14-9

Department of Gastroenterology, Guy's and St. Thomas' NHS Foundation Trust and King's College London, London, UK.

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January 2011

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.

Nat Genet 2010 Dec;42(12):1118-25

Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel, Kiel, Germany.

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December 2010

Colocalization analysis in fluorescence micrographs: verification of a more accurate calculation of pearson's correlation coefficient.

Microsc Microanal 2010 Dec 15;16(6):710-24. Epub 2010 Oct 15.

PerkinElmer, Viscount Centre II, Millburn Hill Road, Warwick University Science Park, Coventry CV4 7HS, UK.

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December 2010

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls.

Authors:
Nick Craddock Matthew E Hurles Niall Cardin Richard D Pearson Vincent Plagnol Samuel Robson Damjan Vukcevic Chris Barnes Donald F Conrad Eleni Giannoulatou Chris Holmes Jonathan L Marchini Kathy Stirrups Martin D Tobin Louise V Wain Chris Yau Jan Aerts Tariq Ahmad T Daniel Andrews Hazel Arbury Anthony Attwood Adam Auton Stephen G Ball Anthony J Balmforth Jeffrey C Barrett Inês Barroso Anne Barton Amanda J Bennett Sanjeev Bhaskar Katarzyna Blaszczyk John Bowes Oliver J Brand Peter S Braund Francesca Bredin Gerome Breen Morris J Brown Ian N Bruce Jaswinder Bull Oliver S Burren John Burton Jake Byrnes Sian Caesar Chris M Clee Alison J Coffey John M C Connell Jason D Cooper Anna F Dominiczak Kate Downes Hazel E Drummond Darshna Dudakia Andrew Dunham Bernadette Ebbs Diana Eccles Sarah Edkins Cathryn Edwards Anna Elliot Paul Emery David M Evans Gareth Evans Steve Eyre Anne Farmer I Nicol Ferrier Lars Feuk Tomas Fitzgerald Edward Flynn Alistair Forbes Liz Forty Jayne A Franklyn Rachel M Freathy Polly Gibbs Paul Gilbert Omer Gokumen Katherine Gordon-Smith Emma Gray Elaine Green Chris J Groves Detelina Grozeva Rhian Gwilliam Anita Hall Naomi Hammond Matt Hardy Pile Harrison Neelam Hassanali Husam Hebaishi Sarah Hines Anne Hinks Graham A Hitman Lynne Hocking Eleanor Howard Philip Howard Joanna M M Howson Debbie Hughes Sarah Hunt John D Isaacs Mahim Jain Derek P Jewell Toby Johnson Jennifer D Jolley Ian R Jones Lisa A Jones George Kirov Cordelia F Langford Hana Lango-Allen G Mark Lathrop James Lee Kate L Lee Charlie Lees Kevin Lewis Cecilia M Lindgren Meeta Maisuria-Armer Julian Maller John Mansfield Paul Martin Dunecan C O Massey Wendy L McArdle Peter McGuffin Kirsten E McLay Alex Mentzer Michael L Mimmack Ann E Morgan Andrew P Morris Craig Mowat Simon Myers William Newman Elaine R Nimmo Michael C O'Donovan Abiodun Onipinla Ifejinelo Onyiah Nigel R Ovington Michael J Owen Kimmo Palin Kirstie Parnell David Pernet John R B Perry Anne Phillips Dalila Pinto Natalie J Prescott Inga Prokopenko Michael A Quail Suzanne Rafelt Nigel W Rayner Richard Redon David M Reid Renwick Susan M Ring Neil Robertson Ellie Russell David St Clair Jennifer G Sambrook Jeremy D Sanderson Helen Schuilenburg Carol E Scott Richard Scott Sheila Seal Sue Shaw-Hawkins Beverley M Shields Matthew J Simmonds Debbie J Smyth Elilan Somaskantharajah Katarina Spanova Sophia Steer Jonathan Stephens Helen E Stevens Millicent A Stone Zhan Su Deborah P M Symmons John R Thompson Wendy Thomson Mary E Travers Clare Turnbull Armand Valsesia Mark Walker Neil M Walker Chris Wallace Margaret Warren-Perry Nicholas A Watkins John Webster Michael N Weedon Anthony G Wilson Matthew Woodburn B Paul Wordsworth Allan H Young Eleftheria Zeggini Nigel P Carter Timothy M Frayling Charles Lee Gil McVean Patricia B Munroe Aarno Palotie Stephen J Sawcer Stephen W Scherer David P Strachan Chris Tyler-Smith Matthew A Brown Paul R Burton Mark J Caulfield Alastair Compston Martin Farrall Stephen C L Gough Alistair S Hall Andrew T Hattersley Adrian V S Hill Christopher G Mathew Marcus Pembrey Jack Satsangi Michael R Stratton Jane Worthington Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem Ouwehand Miles Parkes Nazneen Rahman John A Todd Nilesh J Samani Peter Donnelly

Nature 2010 Apr;464(7289):713-20

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April 2010

Pharmacogenomics in the treatment of inflammatory bowel disease.

Pharmacogenomics 2010 Mar;11(3):421-37

Department of Gastroenterology, 1st Floor, College House, St Thomas' Hospital, Lambeth Palace Road, London, SE1 7EH, UK.

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March 2010

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.

Nat Genet 2009 Dec 15;41(12):1330-4. Epub 2009 Nov 15.

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December 2009

The contribution of deleterious DPYD gene sequence variants to fluoropyrimidine toxicity in British cancer patients.

Cancer Chemother Pharmacol 2010 Jan 1;65(2):403-6. Epub 2009 Oct 1.

Department of Gastroenterology, Guy's and St Thomas' Hospital NHS Foundation Trust, College House, St Thomas' Hospital, London, UK.

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January 2010

The mechanisms and efficacy of probiotics in the prevention of Clostridium difficile-associated diarrhoea.

Lancet Infect Dis 2009 Apr;9(4):237-44

Nutritional Sciences Division, King's College London, London, UK.

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April 2009

Further experience with the use of 6-thioguanine in patients with Crohn's disease.

Inflamm Bowel Dis 2008 Oct;14(10):1399-405

Department of Gastroenterology, Guy's & St. Thomas' Hospitals NHS Foundation Trust, London SE1 7EH, United Kingdom.

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October 2008

Gastrointestinal microbiota in irritable bowel syndrome: their role in its pathogenesis and treatment.

Am J Gastroenterol 2008 Jun 29;103(6):1557-67. Epub 2008 May 29.

Diet and Gastrointestinal Health, Nutritional Sciences Division, King's College London, London, United Kingdom.

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June 2008

Diverse effects of the CARD15 and IBD5 loci on clinical phenotype in 630 patients with Crohn's disease.

Eur J Gastroenterol Hepatol 2008 Jan;20(1):37-45

Division of Genetics and Molecular Medicine, King's College London School of Medicine, Guy's Hospital, London, UK.

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January 2008